CN106588696B - 一种反式α,β-不饱和腈类化合物的制备方法 - Google Patents
一种反式α,β-不饱和腈类化合物的制备方法 Download PDFInfo
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- CN106588696B CN106588696B CN201611123657.2A CN201611123657A CN106588696B CN 106588696 B CN106588696 B CN 106588696B CN 201611123657 A CN201611123657 A CN 201611123657A CN 106588696 B CN106588696 B CN 106588696B
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- benzyl alcohol
- methanol
- alcohol
- molar ratio
- acetonitrile
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Abstract
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Application Number | Priority Date | Filing Date | Title |
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CN201611123657.2A CN106588696B (zh) | 2016-12-08 | 2016-12-08 | 一种反式α,β-不饱和腈类化合物的制备方法 |
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CN201611123657.2A CN106588696B (zh) | 2016-12-08 | 2016-12-08 | 一种反式α,β-不饱和腈类化合物的制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN106588696A CN106588696A (zh) | 2017-04-26 |
CN106588696B true CN106588696B (zh) | 2018-12-25 |
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CN201611123657.2A Active CN106588696B (zh) | 2016-12-08 | 2016-12-08 | 一种反式α,β-不饱和腈类化合物的制备方法 |
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Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS61189272A (ja) * | 1985-02-15 | 1986-08-22 | Taisho Pharmaceut Co Ltd | イミダゾ−ル誘導体 |
JO3429B1 (ar) * | 2001-08-13 | 2019-10-20 | Janssen Pharmaceutica Nv | مشتقات برميدينات مثبطة فيروس الايدز |
US6919331B2 (en) * | 2001-12-10 | 2005-07-19 | Bristol-Myers Squibb Company | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents |
AR075196A1 (es) * | 2009-02-03 | 2011-03-16 | Otsuka Pharma Co Ltd | Un derivado de cianopirimidina para el tratamiento de una enfermedad ocular |
WO2013144191A1 (de) * | 2012-03-29 | 2013-10-03 | Bayer Intellectual Property Gmbh | Substituierte 2 -amino - 3 - cyanopyridine als inhibitoren des natrium calcium austausches und ihre verwendung bei kardiovaskulären erkrankungen |
CN103467481B (zh) * | 2012-06-07 | 2016-08-31 | 上海汇伦生命科技有限公司 | 二氢吡啶类化合物、其组合物、制备方法和用途 |
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2016
- 2016-12-08 CN CN201611123657.2A patent/CN106588696B/zh active Active
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TR01 | Transfer of patent right |
Effective date of registration: 20191213 Address after: No.58 Xinfu Road, Xinjie community, yonganzhou Town, Gaogang District, Taizhou City, Jiangsu Province Patentee after: Zhuo Houqiao Address before: 730070 Anning Road, Anning District, Gansu, Lanzhou, China, No. 967 Patentee before: Northwest Normal University |
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CP02 | Change in the address of a patent holder | ||
CP02 | Change in the address of a patent holder |
Address after: 311800 No.16 Anhua village, Anhua Town, Zhuji City, Shaoxing City, Zhejiang Province Patentee after: Zhuo Houqiao Address before: No.58 Xinfu Road, Xinjie community, yonganzhou Town, Gaogang District, Taizhou City, Jiangsu Province Patentee before: Zhuo Houqiao |
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Effective date of registration: 20211118 Address after: 264200 Tangshan road-19-3, Weihai City, Shandong Province Patentee after: WEIHAI YUANHANG TECHNOLOGY DEVELOPMENT CO.,LTD. Address before: 311800 No.16 Anhua village, Anhua Town, Zhuji City, Shaoxing City, Zhejiang Province Patentee before: Zhuo Houqiao |