CN106581341A - Narcotic drug - Google Patents

Narcotic drug Download PDF

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Publication number
CN106581341A
CN106581341A CN201510683266.5A CN201510683266A CN106581341A CN 106581341 A CN106581341 A CN 106581341A CN 201510683266 A CN201510683266 A CN 201510683266A CN 106581341 A CN106581341 A CN 106581341A
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CN
China
Prior art keywords
parts
narcotic drug
anesthesia
herba
radix
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Pending
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CN201510683266.5A
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Chinese (zh)
Inventor
陈修仕
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GUIZHOU RUNSHENG PHARMACEUTICAL Co Ltd
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GUIZHOU RUNSHENG PHARMACEUTICAL Co Ltd
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Priority to CN201510683266.5A priority Critical patent/CN106581341A/en
Publication of CN106581341A publication Critical patent/CN106581341A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a narcotic drug, which is prepared from the following raw materials in parts by weight: 8-10 parts of herba houttuyniae, 11-16 parts of herba menthae, 2-3 parts of toad venom, 2-3 parts of pepper, 8-10 parts of herba asari cum radice, 8-10 parts of raw kusnezoff monkshood root, 11-16 parts of flos daturae, 8-12 parts of white peony root, 8-10 parts of total herb of radix angelicae sinensis, 8-10 parts of fried arisaema cum bile, 8-10 parts of pericarpium papaveris, 11-16 parts of radix aconiti kusenzoffii and 8-14 parts of radix zanthoxyli. The narcotic drug provided by the invention, which is a traditional Chinese medicinal preparation, is low in toxic and side effects and is quite suitable for local anesthesia and surface anesthesia, and meanwhile, the narcotic drug is convenient to use. The narcotic drug is applicable to local anesthesia and surface skin anesthesia, and the narcotic drug has an anti-shock effect. Results on 100 clinical cases show that the effective rate of the narcotic drug for operative anesthesia reaches 97.7% or above (local skin is painless and the feeling of being painful is avoided in an operative process) and and the ineffective rate of the narcotic drug is just 2.3% or less (local skin is anesthetized and is painless, and light feeling of being painful is caused in the operative process).

Description

A kind of narcotics
Technical field
The present invention relates to a kind of narcotics, belong to narcotics technical field.
Background technology
From for medical angle, anesthesia is meant that and make patient overall by medicine or other methods or locally lose sensibility, and to reach painless purpose, is that operative treatment or other medical examinations treatments provide condition.In clinical operation, especially in local anesthesia operation, it is required for using anesthetis.At present, generally anaesthetized or topical anesthesia is carried out by pad pasting using the method for the injection anesthetis such as procaine and lignocaine or conduction block.Existing anesthesia method operation is comparatively laborious, while also having the risk of anesthesia.Accordingly, it would be desirable to a kind of new Chinese medicinal narcotic is preferably implementing local anesthesia.
The content of the invention
It is an object of the present invention to provide a kind of narcotics.The narcotics have good local anaesthetic effect, and easy to use and safe.
Technical scheme:A kind of narcotics, by the raw material of following composition by weight ratio:8 one 10 parts of Herba Houttuyniae, 11 1 16 parts of Herba Menthae, 2 one 3 parts of Venenum Bufonis, 2 one 3 parts of Fructus Piperiss, 8 one 10 parts of Herba Asari, 8 one 10 parts of SHENGCAO bird, 11 1 16 parts of Flos Daturae, 8 one 12 parts of CHUANSHAO, 8 one 10 parts of Radix Angelicae Sinensis, 8 one 10 parts of Rhizoma Arisaematis of stir-fry, 8 one 10 parts of Pericarpium Papaveris, 11-16 parts of Radix Aconiti, 8-14 parts of Radix Zanthoxyli are made.
Aforesaid narcotics, by the raw material of following composition by weight ratio:8 one 10 parts of Herba Houttuyniae, 11 1 13 parts of Herba Menthae, 2 one 3 parts of Venenum Bufonis, 2 one 3 parts of Fructus Piperiss, 8 one 10 parts of Herba Asari, 8 one 10 parts of SHENGCAO bird, 11 1 13 parts of Flos Daturae, 8 one 12 parts of CHUANSHAO, 8 one 10 parts of Radix Angelicae Sinensis, 8 one 10 parts of Rhizoma Arisaematis of stir-fry, 8 one 10 parts of Pericarpium Papaveris, 12-14 parts of Radix Aconiti, 10-12 parts of Radix Zanthoxyli are made.
Aforesaid narcotics, by the raw material of following composition by weight ratio:9 parts of Herba Houttuyniae, 12 parts of Herba Menthae, 2 parts of Venenum Bufonis, 3 parts of Fructus Piperiss, 9 parts of Herba Asari, 9 parts of SHENGCAO bird, 12 parts of Flos Daturae, 10 parts of CHUANSHAO, 9 parts of Radix Angelicae Sinensis, 9 parts of Rhizoma Arisaematis of stir-fry, 9 parts of Pericarpium Papaveris, 13 parts of Radix Aconiti, 11 parts of Radix Zanthoxyli are made.
In the present invention, Flos Daturae:Containing alkaloid, also containing atropine;With the effect that narcotic analgesic, spasmolytic are only jerked.
Herba Menthae:Pungent, cool, return lung, Liver Channel have a diverging wind heat, dispersing the stagnated live-QI to relieve the stagnation of QI and it is antipruritic the effects such as.
Venenum Bufonis:Venenum Bufonis and ingredient have 80 Venenum Bufonis ethanol extract of local anesthetic action to have surface anesthetic effect, in rabbit corneal and people's tongue test, act on slower and lasting than Anethaine, big compared with cocaine 30-60 times, and have no stimulation.
Fructus Piperiss:There is sedation and strengthen the central inhibitory action of other central nervous system's pharmacy.
Herba Asari:Its volatile oil has an obvious central inhibitory action, and low dose can make that animal is quiet, taming, autonomic activitieses are reduced;Heavy dose can make animal sleep, and have obvious anticonvulsant action.Herba Asari decoct is gavaged.
SHENGCAO bird:Bird head alkali to Mucocutaneous sensory nerve ending produce stimulation, have itch, thermal sensation, then suppress and be in local anesthesia effect.Clinically ingredients is made for topical anesthesia with SHENGCAO bird and his medicine;Or crude drug is fitted over into external in plaster, there is narcotic analgesic to act on.
CHUANSHAO:Blood-activating and qi-promoting, wind-expelling pain-stopping, for pacifying nerve.
Radix Angelicae Sinensis:Radix Angelicae Sinensis volatile oil has calmness, hypnosis, analgesia, anesthesia etc. to act on.
Fry Rhizoma Arisaematis:Micro- have pungent gas, the peppery and numb tongue of taste, with scattered wind, eliminating the phlegm, relieving convulsion, pain relieving work(.
Pericarpium Papaveriss:Containing various alkaloids, morphine, codeine and thebaine, Central nervous have excitement, analgesia, antitussive and syngignoscism;Opium poppy alkali, narcotine etc. have obvious spasmolysises to smooth muscle.
Radix Aconiti:Acrid in the mouth, hardship, property heat, cure mainly anemofrigid-damp arthralgia, arthralgia, trusted subordinate's crymodynia, colic of cold type and have a pain.
Radix Zanthoxyli:It is bitter in the mouth, pungent, it is mild-natured, cure mainly traumatic injury, rheumatic arthralgia, stomachache, toothache that qi depression to blood stasis causes, venom;The burning hot wound of external treatment soup.
Clinical practice example of the present invention is as follows:
Example one, female, 36 years old, has a lump, need to be cut off on the inside of left breast.Using Traditional Chinese medicine tincture preparation of the present invention, lump region time is applied in repeatedly with swab stick, is performed the operation after 10 minutes, it is painless, recover pain after postoperative 5 hours.
Example two, man, 42 years old, have cacodontia 1, need operation to pull out in mouth.Using Traditional Chinese medicine tincture preparation of the present invention, periodontal is applied in repeatedly with swab stick, tooth pulling surgery is carried out after 5 minutes, it is painless.
Example three, man, 39 years old, lower limb were scratched, wound about 10cm, after carrying out primary haemostasis process, need to carry out further stitching processing.Using Traditional Chinese medicine tincture preparation of the present invention, sutured after being applied in repeatedly periwound skin 3,10 minutes, it is painless in art.
Beneficial effects of the present invention:The present invention adopts Chinese medicine preparation, and toxic and side effects are little, is very suitable for local anesthesia and topical anesthesia, meanwhile, it is easy to use.Suitable for local anesthesia and surface skin anesthesia, the effect with antibody gram.From the point of view of Jing 100 results for using of clinic, up to 97.7% (local skin is painless, without pain in operation process), inefficiency is 2.3% (local skin is benumbed, and without pain has slight pain in operation process) to surgery anesthesia effective percentage.
Specific embodiment
Invention is further described with reference to embodiment, but is not intended as the foundation limited to invention.
Embodiments of the invention 1:A kind of narcotics, by the raw material of following composition by weight ratio:8 parts of Herba Houttuyniae, 11 parts of Herba Menthae, 2 parts of Venenum Bufonis, 2 parts of Fructus Piperiss, 8 parts of Herba Asari, 8 parts of SHENGCAO bird, 11 parts of Flos Daturae, 12 parts of CHUANSHAO, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Arisaematis of stir-fry, 10 parts of Pericarpium Papaveris, 16 parts of Radix Aconiti, 14 parts of Radix Zanthoxyli are made.
Embodiments of the invention 2:A kind of narcotics, by the raw material of following composition by weight ratio:10 parts of Herba Houttuyniae, 16 parts of Herba Menthae, 3 parts of Venenum Bufonis, 3 parts of Fructus Piperiss, 10 parts of Herba Asari, 8 parts of SHENGCAO bird, 11 parts of Flos Daturae, 8 parts of CHUANSHAO, 10 parts of Radix Angelicae Sinensis, 8 parts of Rhizoma Arisaematis of stir-fry, 8 parts of Pericarpium Papaveris, 11 parts of Radix Aconiti, 8 parts of Radix Zanthoxyli are made.
Embodiments of the invention 3:A kind of narcotics, by the raw material of following composition by weight ratio:9 parts of Herba Houttuyniae, 13 parts of Herba Menthae, 3 parts of Venenum Bufonis, 3 parts of Fructus Piperiss, 9 parts of Herba Asari, 9 parts of SHENGCAO bird, 14 parts of Flos Daturae, 10 parts of CHUANSHAO, 9 parts of Radix Angelicae Sinensis, 9 parts of Rhizoma Arisaematis of stir-fry, 9 parts of Pericarpium Papaveris, 13 parts of Radix Aconiti, 11 parts of Radix Zanthoxyli are made.
Embodiments of the invention 4:A kind of narcotics, by the raw material of following composition by weight ratio:9 parts of Herba Houttuyniae, 12 parts of Herba Menthae, 2 parts of Venenum Bufonis, 3 parts of Fructus Piperiss, 9 parts of Herba Asari, 9 parts of SHENGCAO bird, 12 parts of Flos Daturae, 10 parts of CHUANSHAO, 9 parts of Radix Angelicae Sinensis, 9 parts of Rhizoma Arisaematis of stir-fry, 9 parts of Pericarpium Papaveris, 13 parts of Radix Aconiti, 11 parts of Radix Zanthoxyli are made.
The medicine manufacture method 1 of above-described embodiment, above each component is mixed in the ratio in embodiment, is directly soaked in the ethanol with 60% -80%, and soak time is 5-8 days, then filters and makes tincture.
The medicine manufacture method 2 of above-described embodiment, above each component is mixed in the ratio in embodiment, the powder of 130 mesh or so is then ground to, and is then soaked in the ethanol with 60% -80%, and soak time is 3-5 days, then filters and makes tincture.
Using usage:When carrying out local anesthesia, only said medicine need to be coated in anesthesia portion surface 15 minutes or so.
Above the specific descriptions of the present invention are intended to illustrate the implementation of specific embodiment, it is impossible to be not understood as limitation of the present invention.Those of ordinary skill in the art under the teachings of the present invention, can make various variants on the basis of the embodiment for describing in detail, and these variants are should be included within the design of the present invention.Scope of the present invention is only limited by described claims.

Claims (3)

1. a kind of narcotics, it is characterised in that:By the raw material of following composition by weight ratio:Herba Houttuyniae 8 One 10 parts, 11 1 16 parts of Herba Menthae, 2 one 3 parts of Venenum Bufonis, 2 one 3 parts of Fructus Piperiss, 8 one 10 parts of Herba Asari, 8 one 10 parts of SHENGCAO bird, 11 1 16 parts of Flos Daturae, 8 one 12 parts of CHUANSHAO, 8 one 10 parts of Radix Angelicae Sinensis, Fry 8 one 10 parts of Rhizoma Arisaematis, 8 one 10 parts of Pericarpium Papaveris, 11-16 parts of Radix Aconiti, 8-14 parts of Radix Zanthoxyli Make.
2. narcotics according to claim 1, it is characterised in that:By following composition by weight ratio Raw material:8 one 10 parts of Herba Houttuyniae, 11 1 13 parts of Herba Menthae, 2 one 3 parts of Venenum Bufonis, Fructus Piperiss 2 one 3 Part, 8 one 10 parts of Herba Asari, 8 one 10 parts of SHENGCAO bird, 11 1 13 parts of Flos Daturae, CHUANSHAO 8 one 12 Part, 8 one 10 parts of Radix Angelicae Sinensis, 8 one 10 parts of Rhizoma Arisaematis, 8 one 10 parts of Pericarpium Papaveris are fried, Radix Aconiti 12- 14 parts, 10-12 parts of Radix Zanthoxyli is made.
3. narcotics according to claim 2, it is characterised in that:By following composition by weight ratio Raw material:9 parts of Herba Houttuyniae, 12 parts of Herba Menthae, 2 parts of Venenum Bufonis, 3 parts of Fructus Piperiss, 9 parts of Herba Asari, SHENGCAO 9 parts of bird, 12 parts of Flos Daturae, 10 parts of CHUANSHAO, 9 parts of Radix Angelicae Sinensis, 9 parts of Rhizoma Arisaematis of stir-fry, 9 parts of Pericarpium Papaveris, 13 parts of Radix Aconiti, 11 parts of Radix Zanthoxyli are made.
CN201510683266.5A 2015-10-20 2015-10-20 Narcotic drug Pending CN106581341A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510683266.5A CN106581341A (en) 2015-10-20 2015-10-20 Narcotic drug

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Application Number Priority Date Filing Date Title
CN201510683266.5A CN106581341A (en) 2015-10-20 2015-10-20 Narcotic drug

Publications (1)

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CN106581341A true CN106581341A (en) 2017-04-26

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108403886A (en) * 2018-05-10 2018-08-17 无锡市人民医院 A kind of Chinese medicine surgery anesthesia agent production method
CN111420021A (en) * 2020-05-26 2020-07-17 袁浩峥 Traditional Chinese medicine preparation for anesthesia and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108403886A (en) * 2018-05-10 2018-08-17 无锡市人民医院 A kind of Chinese medicine surgery anesthesia agent production method
CN111420021A (en) * 2020-05-26 2020-07-17 袁浩峥 Traditional Chinese medicine preparation for anesthesia and preparation method thereof

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Application publication date: 20170426