CN106580740A - Transparent polymer film for skin wrinkle removal, beautifying and modification and use method thereof - Google Patents
Transparent polymer film for skin wrinkle removal, beautifying and modification and use method thereof Download PDFInfo
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- CN106580740A CN106580740A CN201710014327.8A CN201710014327A CN106580740A CN 106580740 A CN106580740 A CN 106580740A CN 201710014327 A CN201710014327 A CN 201710014327A CN 106580740 A CN106580740 A CN 106580740A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/895—Polysiloxanes containing silicon bound to unsaturated aliphatic groups, e.g. vinyl dimethicone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
- C08G77/04—Polysiloxanes
- C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups
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- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a transparent polymer film for skin wrinkle removal, beautifying and modification and a use method thereof. The method comprises preparing gel containing olefin siloxane, hydrosiloxane, toner and a sun-screening agent, preparing special gel containing a platinum component, uniformly smearing skin with the gel containing olefin siloxane and hydrosiloxane, and then uniformly smearing the skin with the special gel containing the platinum component, wherein the olefin siloxane and hydrosiloxane undergo a cross-linked polymerization reaction to produce the transparent polymer film and the reaction is mild and safe to the skin surface. The transparent polymer film has good air permeability, good elasticity, good adhesion and good tensile strength, is used for facial skin, can effectively cover pouches and wrinkles, can modify the skin defects and correct skin color, can make the skin fine, tender, ruddy and glossy, has a skin water locking function, and can prevent skin moisture loss. The sun-screening agent in the film can effectively prevent UV-caused damage to skin.
Description
Technical field
The invention belongs to synthesize high molecular technical field of biological materials, and in particular to one kind for skin wrinkle, beauty,
The transparent polymer film and its using method of modification.
Background technology
Wrinkle:With advancing age, Skin Cell activity is gradually lowered, and metabolic capacity weakens, and causes regenerative cell number
Mesh speedup is less than cell senescence speed, and aged cells hydratability is low and light aging effect strengthens, cause skin shrinkage with
Moisture retention declines, and increases fibrous tissue deterioration, and wrinkle occurs in skin.The product for smoothing away wrinkles at present and technology mainly include injection
Smoothing wrinkle and crease-resistant class skin care item etc..Injection smoothing wrinkle technology wrinkle improvement effect is held time short, is held time usual 6-9 month;Simultaneously
Adverse reaction rate is high, and only less part people selects injection smoothing wrinkle, especially middle-aged and elderly people to be even more and hold reservation state to injecting smoothing wrinkle
Degree.And nominally the crease-resistant skin care item of energy smoothing wrinkle are more a kind of psychological comforts, from the point of view of Clinical practice effect statistics, real energy
Accomplish that the crease-resistant statistically significant product of smoothing wrinkle does not have substantially.So, people are to safety, the easily demand of smoothing wrinkle product
Urgent.
Skin of face:Skin of face most of time is externally exposed, by extreme temperature, toxin, microorganism, adolescence skin
Adipose gland secretion, ultraviolet radiation and mechanical wounding etc. affect, and make the skin flaws such as skin of face chromogenesises calmness.Solve at present
The product and technology of skin flaw mainly includes hiding flaw class color make-up product, speckle dispelling class skin care item and laser speckle dispelling etc..Hide flaw class color
Adornment product is most to hide the flaw for physics, smears too thin can not reaching and hides flaw effect, smears too thick aobvious grain weight, and skin is unnatural, and skin
Skin breathability is deteriorated, and blocks pore.At present, also the good breathability of skin and naturalness can be kept without a on market,
The good product for hiding flaw effect is played again.In addition, the performance of speckle dispelling class skin care item is also very unsatisfactory, majority can only achieve certain journey
The light speckle effect of degree, effect type product of real energy dispelling stain does not also obtain basic breakthrough.Laser speckle dispelling is shallow for skin
Layer pigmentation has certain curative effect, but can excite color on the contrary not only without therapeutic effect to the deep layer such as chloasma pigmentation
Plain calmness degree increases.The technology and product for solving the skin flaws such as cutaneous pigmentation still has before wide market
Scape.
The content of the invention
In order to overcome the shortcoming and defect of above-mentioned existing product and technology, the present invention innovatively employ it is a kind of have remove
Wrinkle, the screening flaw, and ventilative, beautifying skin conveniently, safely, the transparent polymer film of modification and its using method.
Thin polymer film good permeability involved in the present invention, with good elasticity, adhesive force and tensile strength, uses
In face skin, eye pouch and wrinkle can be effectively covered, while skin flaw and correction skin color can be modified, skin is become at once
Obtain delicate, ruddy and glossy;In addition, the thin film has water lock function to skin, the loss of skin moisture content is prevented;It is anti-in thin film
Shining agent can effectively prevent damage of the ultraviolet to skin.
The gel carrier for being significantly characterized in that olefin-containing siloxanes and hydrogen-based siloxanes of the present invention and containing catalyst component
Gel carrier, this carrier includes but is not limited only to gel.
The purpose of the present invention is realized by below scheme.
It is a kind of for skin wrinkle, beauty, modification transparent polymer film and its using method, comprise the following steps.
(1)The preparation of Blank gel:With carbomer, HANSHENGJIAO, hydroxypropyl methylcellulose, glycerol, Propylene Glycol, water, ethanol,
Triethanolamine is gel prepared by raw material.
(2)The preparation of the gel of olefin-containing siloxanes and hydrogen-based siloxanes:Olefinic siloxane and hydrogen-based siloxanes are dissolved in
Blank gel.
(3)The preparation of the special gel containing catalyst component:Catalyst solution is mixed homogeneously with Blank gel.
(4)Using method:By the gel uniform application of olefinic siloxane and hydrogen-based siloxanes in skin, then uniformly apply
Smear the special gel of catalyst component.
Further.
The preparation of the Blank gel described in step (1):Gel matrix material is not limited to carbomer, HANSHENGJIAO, hydroxypropyl first
Base cellulose;The wetting agent of gel is not limited to glycerol, Propylene Glycol;The solvent of gel is not limited to water, ethanol;The pH adjusting agent of gel
It is not limited to triethanolamine.
Gel described in step (1) contains 0.1~10% gel matrix material, 0.1~20% wetting agent, and 10~95%
Solvent, the pH value of gel is 4.0~8.0.
Toner, sunscreen can be added in gel described in step (1).
Olefinic siloxane described in step (2), preferential vinylsiloxane, comprising but be not limited only to vinylsiloxane.
Olefinic siloxane and hydrogen-based siloxanes ratio described in step (2):Olefinic siloxane and hydrogen-based siloxanes ratio(1
~100):1.
Weight ratio of the olefinic siloxane and hydrogen-based siloxanes described in step (2) in gel:10~70%.
The unsaturated alkyl content 0.1~5% of the olefinic siloxane described in step (2).
The hydrogen-based content 0.1~5% of the hydrogen-based siloxanes described in step (2).
Catalyst described in step (3) is not limited to the catalyst containing platinum, preferred platinum catalyst, containing 0.1~100%
Catalyst solution, the solution concentration of catalyst is 0.001mol/L~10mol/L.
Thin film is formed after smearing described in step (4) can be fitted tightly over more than 20 hours on skin, with good
Elasticity, good breathability, adhesive force and tensile strength.
The present invention mechanism be:Platinum catalysis unsaturated alkyl hydrosilylation, platinum catalyst has high activity and Gao Xuan
Selecting property, olefinic siloxane and hydrogen-based siloxanes are in transparent, the ventilative polymer of platinum catalysis polymerization, and reaction condition is gentle.It is solidifying
Glue is conveniently smeared.
The present invention has the following advantages and beneficial effect relative to prior art:The product that smoothes away wrinkles at present and
Technology mainly includes injection smoothing wrinkle and crease-resistant class skin care item etc., and injection smoothing wrinkle is held time short, and adverse reaction rate is high, resists
Wrinkle class skin care item using effect is little;And current speckle dispelling hides flaw product and technology has certain deficiency, DeGrain.
The transparent polymer film of the present invention, using conveniently, safely, effect substantially, the thin polymer film good permeability, with good
Elasticity, adhesive force and tensile strength, can well cover wrinkle;Meanwhile, toner and sunscreen, thin polymer film are added in gel
The close human body skin of color, can effectively modify the colour of skin, cover skin blemishes, and with water lock sun-proof function.
Description of the drawings
Fig. 1 is the mechanism chemical reaction route map of the present invention.
Specific embodiment
With reference to case study on implementation and accompanying drawing, the present invention is described in further detail, but embodiment of the present invention is not
It is limited to this.
As shown in figure 1, the reagent used by the present invention, material is commercially available the chemical reaction route map of the present invention.
Embodiment 1:It is a kind of for skin wrinkle, beauty, modification transparent polymer film preparation.
(1)The preparation of Blank gel:Be placed in 80% purified water with the carbomer for weighing 1.0% be dipped to complete swelling into
Colloid, the glycerol for adding 17.2%, the triethanolamine of the lower addition 1.8% of stirring, stirring obtains final product Blank gel, determines pH value
5.30。
(2)The preparation of the gel of olefin-containing siloxanes and hydrogen-based siloxanes:By 40% vinylsiloxane and 10% hydrogen
Radical siloxane is dissolved in Blank gel.
(3)The preparation of the special gel containing catalyst component:By the platinum catalyst solution of 1% 0.1mol/L and sky
White gel mix homogeneously.
(4)Using method:By the gel uniform application of vinylsiloxane and hydrogen-based siloxanes in skin, then uniformly apply
The special gel of platinum catalyst composition is smeared, transparent polymer film is produced immediately and is covered in skin.
Embodiment 2:It is a kind of for skin wrinkle, beauty, modification transparent polymer film preparation.
(1)The preparation of Blank gel:It is placed in 85% purified water with the HANSHENGJIAO for weighing 1.2% and is dipped to complete swelling
Into colloid, add 12.3% Propylene Glycol, stir the triethanolamine of lower addition 1.5%, stirring obtains final product Blank gel, determines pH
Value 5.10.
(2)The preparation of the gel of olefin-containing siloxanes and hydrogen-based siloxanes:By 40% vinylsiloxane, 10% hydrogen
Radical siloxane is dissolved in Blank gel, by 6% titanium dioxide, 0.4% red ferric oxide, 0.2% yellow ferric oxide, 0.2% black oxygen
Change ferrum and be scattered in above-mentioned gel.
(3)The preparation of the special gel containing catalyst component:By the platinum catalyst solution of 2% 0.1mol/L and sky
White gel mix homogeneously.
(4)Using method:By the gel uniform application of vinylsiloxane and hydrogen-based siloxanes in skin, then uniformly apply
The special gel of platinum catalyst composition is smeared, transparent polymer film is produced immediately and is covered in skin.
Embodiment 3:It is a kind of for skin wrinkle, beauty, modification transparent polymer film preparation.
(1)The preparation of Blank gel:It is placed in 75% purified water with the hydroxypropyl methylcellulose for weighing 2% and has been dipped to
Colloid being swelled into entirely, 21% glycerol being added, is stirred the triethanolamine of lower addition 2%, stirring obtains final product Blank gel, determines pH
Value 5.30.
(2)The preparation of the gel of olefin-containing siloxanes and hydrogen-based siloxanes:By 30% vinylsiloxane, 5% hydrogen-based
Siloxanes is dissolved in Blank gel, 6% titanium dioxide, 2% Muscovitum, 4% octyl methoxycinnamate is dispersed in above-mentioned
Gel.
(3)The preparation of the special gel containing catalyst component:By the platinum catalyst solution of 1% 0.5mol/L and sky
White gel mix homogeneously.
(4)Using method:By the gel uniform application of vinylsiloxane and hydrogen-based siloxanes in skin, then uniformly
The special gel of platinum catalyst composition is smeared, transparent polymer film is produced immediately and is covered in skin.
Above-described embodiment is the present invention preferably embodiment, but embodiments of the present invention not by above-described embodiment
Limit, it is other it is any without departing from essence of the invention and the change made under raw material, modification, replacement, combine, simplify, all should
For equivalent substitute mode, it is included within protection scope of the present invention.
Claims (2)
1. it is a kind of for skin wrinkle, beauty, the transparent polymer film of modification and its using method, it is characterised in that to include
Following steps:
(1)The preparation of Blank gel:With carbomer, HANSHENGJIAO, hydroxypropyl methylcellulose, glycerol, Propylene Glycol, water, ethanol, three second
Hydramine is gel prepared by raw material;
(2)The preparation of the gel of olefin-containing siloxanes and hydrogen-based siloxanes:Olefinic siloxane and hydrogen-based siloxanes are dissolved in into blank
Gel;
(3)The preparation of the special gel containing catalyst component:Catalyst component is mixed homogeneously with Blank gel;
(4)Using method:By the gel uniform application of olefinic siloxane and hydrogen-based siloxanes in skin, then uniform application catalysis
The special gel of agent composition.
2. according to claim 1 a kind of for skin wrinkle, beauty, the transparent polymer film of modification and its user
Method, it is characterised in that:
The gel carrier for being significantly characterized in that olefin-containing siloxanes and hydrogen-based siloxanes of step (1) present invention and containing catalyst
The gel carrier of composition, this carrier includes but is not limited only to gel;
The preparation of the Blank gel described in step (1):Gel matrix material is not limited to carbomer, HANSHENGJIAO, hydroxypropyl methylcellulose
Element;The wetting agent of gel is not limited to glycerol, Propylene Glycol;The solvent of gel is not limited to water, ethanol;The pH adjusting agent of gel is not limited to
Triethanolamine;
Gel described in step (1) contain 0.1~10% gel matrix material, 0.1~20% wetting agent, 10~95% it is molten
Agent, the pH value of gel is 4.0~8.0;
Toner, sunscreen can be added in gel described in step (1);
Olefinic siloxane described in step (2), preferential vinylsiloxane, comprising but be not limited only to vinylsiloxane;
Olefinic siloxane and hydrogen-based siloxanes ratio described in step (2):Olefinic siloxane and hydrogen-based siloxanes ratio(1~
100):1;
Weight ratio of the olefinic siloxane and hydrogen-based siloxanes described in step (2) in gel:10~70%;
The unsaturated alkyl content 0.1~5% of the olefinic siloxane described in step (2);
The hydrogen-based content 0.1~5% of the hydrogen-based siloxanes described in step (2);
Catalyst described in step (3) is included but is not limited only to the catalyst containing platinum, containing 0.1~100% catalyst solution,
The solution concentration of catalyst is 0.001mol/L~10mol/L;
Thin film is formed after smearing described in step (4) can be fitted tightly over more than 20 hours on skin, with favorable elasticity,
Good breathability, adhesive force and tensile strength.
Priority Applications (1)
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CN201710014327.8A CN106580740A (en) | 2017-01-10 | 2017-01-10 | Transparent polymer film for skin wrinkle removal, beautifying and modification and use method thereof |
Applications Claiming Priority (1)
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CN201710014327.8A CN106580740A (en) | 2017-01-10 | 2017-01-10 | Transparent polymer film for skin wrinkle removal, beautifying and modification and use method thereof |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107362065A (en) * | 2017-09-17 | 2017-11-21 | 广东伊茗药业有限公司 | A kind of novel skin nursing gel |
WO2019098736A1 (en) * | 2017-11-17 | 2019-05-23 | (주)아모레퍼시픽 | Pack composition |
CN109966176A (en) * | 2017-12-28 | 2019-07-05 | 伊丽英 | Skin wrinkle-removing composition and application thereof |
CN110559212A (en) * | 2019-10-14 | 2019-12-13 | 南京医科大学 | Polysiloxane moisturizing and wrinkle removing mask and using method thereof |
CN110997025A (en) * | 2017-07-31 | 2020-04-10 | 美珂斯株式会社 | Composition for preparing artificial skin comprising fibrous polymer and method for preparing artificial skin using the same |
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CN101432340A (en) * | 2006-03-21 | 2009-05-13 | 陶氏康宁公司 | Silicone polyether elastomer gels |
CN101945950A (en) * | 2008-01-17 | 2011-01-12 | 陶氏康宁公司 | Film forming, silicone containing compositions |
CN103356402A (en) * | 2013-07-26 | 2013-10-23 | 联谊水处理技术(大连)有限公司 | Skin-care product additive modified by polysiloxane and dodecene |
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2017
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Publication number | Priority date | Publication date | Assignee | Title |
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CN101432340A (en) * | 2006-03-21 | 2009-05-13 | 陶氏康宁公司 | Silicone polyether elastomer gels |
CN101432341A (en) * | 2006-03-21 | 2009-05-13 | 陶氏康宁公司 | Silicone-organic elastomer gels |
CN101945950A (en) * | 2008-01-17 | 2011-01-12 | 陶氏康宁公司 | Film forming, silicone containing compositions |
CN103356402A (en) * | 2013-07-26 | 2013-10-23 | 联谊水处理技术(大连)有限公司 | Skin-care product additive modified by polysiloxane and dodecene |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110997025A (en) * | 2017-07-31 | 2020-04-10 | 美珂斯株式会社 | Composition for preparing artificial skin comprising fibrous polymer and method for preparing artificial skin using the same |
CN107362065A (en) * | 2017-09-17 | 2017-11-21 | 广东伊茗药业有限公司 | A kind of novel skin nursing gel |
WO2019098736A1 (en) * | 2017-11-17 | 2019-05-23 | (주)아모레퍼시픽 | Pack composition |
KR20190056772A (en) * | 2017-11-17 | 2019-05-27 | (주)아모레퍼시픽 | Composition for pack |
KR102429034B1 (en) | 2017-11-17 | 2022-08-04 | (주)아모레퍼시픽 | Composition for pack |
CN109966176A (en) * | 2017-12-28 | 2019-07-05 | 伊丽英 | Skin wrinkle-removing composition and application thereof |
CN110559212A (en) * | 2019-10-14 | 2019-12-13 | 南京医科大学 | Polysiloxane moisturizing and wrinkle removing mask and using method thereof |
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