CN106580543A - Conformal body surface treatment system based on liquid metal - Google Patents
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Abstract
本发明公开一种基于液态金属的适形化体表治疗系统，能够根据受治疗者的待治疗体表区域形貌进行适形化的治疗。所述系统包括：三维体表形貌数据采集装置、液态金属三维柔性电路印制装置和体表治疗控制装置；其中，所述三维体表形貌数据采集装置，用于采集待治疗区域的三维体表形貌数据；所述液态金属三维柔性电路印制装置，用于根据所述三维体表形貌数据，利用液态金属材料打印三维柔性电路，其中，所述三维柔性电路适形化且适形化附着于所述待治疗区域；所述三维柔性电路，由所述体表治疗控制装置控制对所述待治疗区域进行物理刺激治疗。本发明具有适形化、定制化、适用范围广、便于功能扩展升级等优点。
The invention discloses a liquid metal-based conformal body surface treatment system, which can perform conformal treatment according to the topography of a subject's body surface area to be treated. The system includes: a three-dimensional body surface topography data acquisition device, a liquid metal three-dimensional flexible circuit printing device, and a body surface treatment control device; wherein, the three-dimensional body surface topography data acquisition device is used to collect three-dimensional Body surface topography data; the liquid metal three-dimensional flexible circuit printing device is used to print three-dimensional flexible circuits using liquid metal materials according to the three-dimensional body surface topography data, wherein the three-dimensional flexible circuit is conformal and adaptable The three-dimensional flexible circuit is controlled by the body surface treatment control device to perform physical stimulation therapy on the area to be treated. The invention has the advantages of conformability, customization, wide application range, convenient function expansion and upgrading, and the like.
Description
技术领域technical field
本发明涉及电子医疗设备技术领域，具体涉及一种基于液态金属的适形化体表治疗系统。The invention relates to the technical field of electronic medical equipment, in particular to a liquid metal-based conformal body surface treatment system.
背景技术Background technique
体表是人体与外界环节接触、作用及进行物质交换的面积最大的器官和组织，一方面是反映人体健康状态的重要表征，另一方面，对位于体表组织、器官(如皮肤)的保养本身同样具有现实意义并被广为关注，更为重要的是的，通过体表对人体健康进行干预和治疗，也往往是针对诸多疾病或健康隐患的最为直接、有效的手段。The body surface is the organ and tissue with the largest area of contact, action and material exchange between the human body and the outside world. On the one hand, it is an important indicator of the health status of the human body. It also has practical significance and has been widely concerned. More importantly, the intervention and treatment of human health through the body surface is often the most direct and effective means for many diseases or health risks.
在医疗领域中，通过对体表进行加热、光照、电磁脉冲刺激或是贴附药剂，都可以针对各类不同的病症、损伤或健康隐患起到治疗疾病、消除肿胀、缓解疼痛等效用；即使在健康人群中，对于美容、护理等皮肤表面的保养，也经常会采用激光照射、护肤品涂抹等方式对皮肤表面进行直接的理化作用。In the medical field, by heating the body surface, lighting, electromagnetic pulse stimulation or attaching drugs, it can treat various diseases, injuries or health risks, such as treating diseases, eliminating swelling, and relieving pain; even In healthy people, for the maintenance of skin surface such as beauty treatment and nursing, laser irradiation and application of skin care products are often used to have direct physical and chemical effects on the skin surface.
然而，现有的体表治疗大多需要使用特定的仪器或装置，一方面往往只具有单一或有限功能，另一方面仪器不能够根据用户体表的形貌进行专门的适应，从而可能造成对部分区域的作用不足或过度。However, most of the existing body surface treatments require the use of specific instruments or devices. On the one hand, they often only have a single or limited function. On the other hand, the instruments cannot be specially adapted to the topography of the user's body surface, which may cause partial Regions are under- or over-active.
发明内容Contents of the invention
本发明的目的在于，提供一种应用范围更加广泛的基于液态金属的适形化体表治疗系统，能够根据受治疗者的待治疗体表区域形貌进行适形化的治疗。The purpose of the present invention is to provide a liquid metal-based conformal body surface treatment system with a wider application range, which can perform conformal treatment according to the shape of the subject's body surface area to be treated.
为此目的，本发明提出一种基于液态金属的适形化体表治疗系统，包括：For this purpose, the present invention proposes a conformal body surface treatment system based on liquid metal, comprising:
三维体表形貌数据采集装置、液态金属三维柔性电路印制装置和体表治疗控制装置；其中，Three-dimensional body surface topography data acquisition device, liquid metal three-dimensional flexible circuit printing device and body surface treatment control device; among them,
所述三维体表形貌数据采集装置，用于采集待治疗区域的三维体表形貌数据；The three-dimensional body surface topography data acquisition device is used to collect three-dimensional body surface topography data of the area to be treated;
所述液态金属三维柔性电路印制装置，用于根据所述三维体表形貌数据，利用液态金属材料打印三维柔性电路，其中，所述三维柔性电路适形化且适形化附着于所述待治疗区域；The liquid metal three-dimensional flexible circuit printing device is used to print a three-dimensional flexible circuit using a liquid metal material according to the three-dimensional body surface topography data, wherein the three-dimensional flexible circuit is conformal and conformally attached to the the area to be treated;
所述三维柔性电路，由所述体表治疗控制装置控制对所述待治疗区域进行物理刺激治疗。The three-dimensional flexible circuit is controlled by the body surface treatment control device to perform physical stimulation treatment on the area to be treated.
本发明实施例所述的基于液态金属的适形化体表治疗系统，通过液态金属三维柔性电路印制装置，根据待治疗区域的三维体表形貌数据，利用液态金属材料打印适形化且适形化附着于所述待治疗区域的三维柔性电路对所述待治疗区域进行物理刺激治疗，因而，相较于具有有限功能、不能够根据用户体表的形貌进行专门的适应的现有技术，本发明能够根据受治疗者的待治疗体表区域形貌进行适形化的治疗，应用范围更广。In the liquid metal-based conformal body surface treatment system described in the embodiment of the present invention, the liquid metal three-dimensional flexible circuit printing device is used to print conformal and The three-dimensional flexible circuit conformally attached to the area to be treated performs physical stimulation therapy on the area to be treated. Therefore, compared with the existing technology, the present invention can perform conformal treatment according to the topography of the subject's body surface area to be treated, and has a wider application range.
附图说明Description of drawings
图1为本发明基于液态金属的适形化体表治疗系统一实施例的结构示意图；Fig. 1 is a schematic structural view of an embodiment of the liquid metal-based conformal body surface treatment system of the present invention;
图2为本发明基于液态金属的适形化体表治疗系统另一实施例的结构示意图；Fig. 2 is a structural schematic diagram of another embodiment of the liquid metal-based conformal body surface treatment system of the present invention;
图3为本发明基于液态金属的适形化体表治疗系统又一实施例的结构示意图；Fig. 3 is a structural schematic diagram of another embodiment of the liquid metal-based conformal body surface treatment system of the present invention;
图4为本发明基于液态金属的适形化体表治疗系统又一实施例的结构示意图。Fig. 4 is a structural schematic diagram of another embodiment of the liquid metal-based conformal body surface treatment system of the present invention.
具体实施方式detailed description
为使本发明实施例的目的、技术方案和优点更加清楚，下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚地描述，显然，所描述的实施例是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are the Some, but not all, embodiments are invented. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
如图1所示，本实施例公开一种基于液态金属的适形化体表治疗系统，包括：As shown in Figure 1, this embodiment discloses a conformal body surface treatment system based on liquid metal, including:
三维体表形貌数据采集装置1、液态金属三维柔性电路印制装置2和体表治疗控制装置3；其中，Three-dimensional body surface topography data acquisition device 1, liquid metal three-dimensional flexible circuit printing device 2 and body surface treatment control device 3; wherein,
所述三维体表形貌数据采集装置1，用于采集待治疗区域的三维体表形貌数据；The three-dimensional body surface topography data acquisition device 1 is used to collect three-dimensional body surface topography data of an area to be treated;
所述液态金属三维柔性电路印制装置2，用于根据所述三维体表形貌数据，利用液态金属材料打印三维柔性电路4，其中，所述三维柔性电路4适形化且适形化附着于所述待治疗区域；The liquid metal three-dimensional flexible circuit printing device 2 is used to print a three-dimensional flexible circuit 4 using a liquid metal material according to the three-dimensional body surface topography data, wherein the three-dimensional flexible circuit 4 is conformal and conformally attached in the area to be treated;
所述三维柔性电路4，由所述体表治疗控制装置3控制对所述待治疗区域进行物理刺激治疗。The three-dimensional flexible circuit 4 is controlled by the body surface treatment control device 3 to perform physical stimulation treatment on the area to be treated.
本发明实施例中，所述待治疗区域包括全身各处的身体表面、附着其上或覆盖于其下的脂肪、软组织、韧带、关节、肌肉、内脏等组织和器官，待治疗对象为可通过体表治疗的生理状态或病变，包括细菌、真菌、寄生虫等微生物感染造成的体表疾病，外部物理(日晒、高温、低温、灼烧、电离辐射)、化学(酸、碱、毒素)、机械(碰撞、刮擦、扭、挫、割、刺)、自身免疫等因素造成的皮肤或软组织损伤，皱纹、色斑、松弛等皮肤变性，以及位于皮肤或体内组织器官的穴位、血管、脂肪、肿瘤等；所述三维体表形貌数据采集装置包括数据采集单元和数据重建单元，所述数据采集单元，用于采集待治疗区域的体表数据，其采集体表数据的方式包括多角度可见光或红外光拍照、可见光或红外光阵列扫描、超声波反射、射频或雷达波反射、磁共振断层扫描、X线断层扫描、电阻抗/电容/电感式断层扫描、接触式光学或磁场空间位置传感器扫描或阵列扫描、接触式距离传感器扫描或阵列扫描等，所述数据重建单元，用于对所述数据采集单元采集的数据进行重建，得到待治疗区域的三维体表形貌数据(包括待治疗区域体表不同位置处的三维坐标以及生理状态)；所述液态金属三维柔性电路印制装置是具有以直写、喷墨、喷涂、涂抹、灌注、转印、化学沉积或置换等方式进行三维柔性电路打印、元器件自动放置等功能的仪器的组合或集成，所述液态金属三维柔性电路印制装置根据所述三维体表形貌数据，利用液态金属材料打印适形化所述待治疗区域几何形状以及生理状态的三维柔性电路；所述三维柔性电路可以嵌入各类检测单元及治疗单元，从而能够在体表治疗控制装置的控制下对待治疗区域进行电、磁、声、光、热等形式的体表治疗。In the embodiment of the present invention, the area to be treated includes the body surface everywhere in the whole body, fat attached to or covered under it, soft tissue, ligament, joint, muscle, viscera and other tissues and organs. Physiological states or lesions of body surface treatment, including body surface diseases caused by microbial infections such as bacteria, fungi, and parasites, external physical (sun exposure, high temperature, low temperature, burning, ionizing radiation), chemical (acid, alkali, toxin) , mechanical (collision, scraping, twisting, frustrating, cutting, stabbing), autoimmune and other factors caused skin or soft tissue damage, skin degeneration such as wrinkles, stains, and relaxation, as well as acupuncture points, blood vessels, Fat, tumor, etc.; the three-dimensional body surface topography data collection device includes a data collection unit and a data reconstruction unit, the data collection unit is used to collect body surface data of the area to be treated, and the way of collecting body surface data includes multiple Angle visible light or infrared light photography, visible light or infrared light array scanning, ultrasonic reflection, radio frequency or radar wave reflection, magnetic resonance tomography, X-ray tomography, electrical impedance/capacitance/inductance tomography, contact optical or magnetic field spatial position Sensor scanning or array scanning, contact distance sensor scanning or array scanning, etc., the data reconstruction unit is used to reconstruct the data collected by the data acquisition unit to obtain the three-dimensional body surface topography data of the area to be treated (including three-dimensional coordinates and physiological states at different positions on the body surface of the treatment area); the liquid metal three-dimensional flexible circuit printing device has the functions of direct writing, inkjet, spraying, smearing, perfusion, transfer printing, chemical deposition or replacement, etc. Combination or integration of instruments with functions such as three-dimensional flexible circuit printing and automatic component placement, the liquid metal three-dimensional flexible circuit printing device uses liquid metal materials to print conformal to the treatment The three-dimensional flexible circuit of the geometric shape of the region and the physiological state; the three-dimensional flexible circuit can be embedded in various detection units and treatment units, so that under the control of the body surface treatment control device, the area to be treated can be controlled by electricity, magnetism, sound, light, heat, etc. and other forms of body surface treatment.
本发明实施例所述的基于液态金属的适形化体表治疗系统，通过液态金属三维柔性电路印制装置，根据待治疗区域的三维体表形貌数据，利用液态金属材料打印适形化且适形化附着于所述待治疗区域的三维柔性电路对所述待治疗区域进行物理刺激治疗，因而，相较于具有有限功能、不能够根据用户体表的形貌进行专门的适应的现有技术，本发明能够根据受治疗者的待治疗体表区域形貌进行适形化的治疗，应用范围更广。In the liquid metal-based conformal body surface treatment system described in the embodiment of the present invention, the liquid metal three-dimensional flexible circuit printing device is used to print conformal and The three-dimensional flexible circuit conformally attached to the area to be treated performs physical stimulation therapy on the area to be treated. Therefore, compared with the existing technology, the present invention can perform conformal treatment according to the topography of the subject's body surface area to be treated, and has a wider application range.
可选地，在本发明基于液态金属的适形化体表治疗系统的另一实施例中，所述液态金属三维柔性电路印制装置，用于将所述三维柔性电路直接印制于所述待治疗区域相应的体表或者先将所述三维柔性电路封装于柔性基底，后将所述柔性基底侧覆盖于所述待治疗区域相应的体表。Optionally, in another embodiment of the liquid metal-based conformal body surface treatment system of the present invention, the liquid metal three-dimensional flexible circuit printing device is used to directly print the three-dimensional flexible circuit on the The body surface corresponding to the area to be treated or the three-dimensional flexible circuit is packaged on a flexible base first, and then the flexible base side is covered on the body surface corresponding to the area to be treated.
可选地，在本发明基于液态金属的适形化体表治疗系统的另一实施例中，所述三维柔性电路包括检测单元和治疗单元，所述体表治疗控制装置包括控制单元；其中，Optionally, in another embodiment of the liquid metal-based conformal body surface treatment system of the present invention, the three-dimensional flexible circuit includes a detection unit and a treatment unit, and the body surface treatment control device includes a control unit; wherein,
所述检测单元，用于采集所述待治疗区域相应的体表处的人体数据，并传输给所述控制单元以及与其连接的终端；The detection unit is used to collect the human body data at the corresponding body surface of the area to be treated, and transmit it to the control unit and the terminal connected thereto;
所述终端通过向所述控制单元发送指令控制所述治疗单元对所述待治疗区域进行物理刺激治疗；The terminal controls the treatment unit to perform physical stimulation treatment on the area to be treated by sending an instruction to the control unit;
所述控制单元根据所述检测单元传输的数据对所述治疗单元的治疗进行调控。The control unit regulates the treatment of the treatment unit according to the data transmitted by the detection unit.
本发明实施例中，可以通过将三维柔性电路依体表形貌适形化布线，将特定的检测与治疗单元准确分布于针对特定作用目标的特定位置，以发挥治疗效用，在三维柔性电路适形化覆盖于所述待治疗体表区域后，对于所述控制单元，可以根据治疗方案设定算法序列，以调控治疗单元的开关、强度、时长、节律等作用参数，并可根据所述的检测单元的反馈实时调整，以实现对所述待治疗对象病变的缓解、治疗或生理状态的改变，所述检测单元与治疗单元，既可以是独立的元器件，也可以是在三维柔性电路中直接印制得到的线圈、射频天线、电极、电热丝、半导体发光器、热电偶、应力传感器、电阻抗传感器等；控制单元可嵌入柔性电路，所述体表治疗控制装置除包括柔性电路上已经设定好治疗方案的嵌入式控制单元之外，在其它实施方式中也可以包括与之相连的计算机设备、智能手机、平板电脑以及智能手表、智能头盔等可穿戴智能终端设备。In the embodiment of the present invention, the specific detection and treatment units can be accurately distributed at specific positions for specific targets by conformal wiring of the three-dimensional flexible circuit according to the body surface topography, so as to exert therapeutic effects. After the body surface area to be treated is covered in shape, for the control unit, an algorithm sequence can be set according to the treatment plan to regulate the treatment unit's switch, intensity, duration, rhythm and other action parameters, and according to the described The feedback of the detection unit is adjusted in real time to achieve the alleviation of the lesion of the object to be treated, the treatment or the change of the physiological state. The detection unit and the treatment unit can be independent components or in a three-dimensional flexible circuit Directly printed coils, radio frequency antennas, electrodes, heating wires, semiconductor light emitters, thermocouples, stress sensors, electrical impedance sensors, etc.; the control unit can be embedded in a flexible circuit, and the body surface treatment control device includes In addition to the embedded control unit that sets the treatment plan, other embodiments may also include connected computer equipment, smart phones, tablet computers, and wearable smart terminal devices such as smart watches and smart helmets.
可选地，在本发明基于液态金属的适形化体表治疗系统的另一实施例中，所述检测单元包括温度传感器、湿度传感器、电化学传感器、电阻抗传感器、分子传感器、声音传感器或应力传感器，所述治疗单元包括能够施加电刺激、磁刺激、光刺激、热刺激、超声刺激或机械振动刺激的电子器件。Optionally, in another embodiment of the liquid metal-based conformal body surface treatment system of the present invention, the detection unit includes a temperature sensor, a humidity sensor, an electrochemical sensor, an electrical impedance sensor, a molecular sensor, an acoustic sensor or A stress sensor, the treatment unit includes electronics capable of applying electrical, magnetic, optical, thermal, ultrasonic or mechanical vibration stimuli.
可选地，在本发明基于液态金属的适形化体表治疗系统的另一实施例中，还包括三维模具打印装置，用于根据所述三维体表形貌数据打印出辅助模具。Optionally, in another embodiment of the liquid metal-based conformal body surface treatment system of the present invention, it further includes a three-dimensional mold printing device for printing out an auxiliary mold according to the three-dimensional body surface topography data.
本发明实施例中，所述三维模具打印装置，还能够通过使用不同材质，对打印出的模具的透明度、硬度、伸缩性等性能参数进行调整，还可以对其进行裁剪、开孔、表面粗糙度处理等。所述辅助模具用途包括为封装或未封装的三维柔性电路提供附着、对所述待治疗区域进行固定、搭载各类外源敏感或靶向类药物等，其整体形态可以是面、头、颈、臂、腿、胸、腰、腹、背、臀、手、足、指、趾、肩、肘、腕、髋、膝、踝、脊柱、骨盆、外生殖器等处的套具、罩具或固定器具，以满足体表治疗的辅助需求。所述外源敏感或靶向类药物包括体表覆盖、涂抹、注射、吸入或口服类药物，能够对覆盖于所述待治疗区域的治疗单元的作用做出响应，以调节其渗透性、吸收性、聚集性、药物活性或对特定作用目标的靶向性。通过结合适形化辅助模具及各类外源敏感或靶向类药物能够对治疗进行调控。In the embodiment of the present invention, the three-dimensional mold printing device can also adjust the performance parameters of the printed mold such as transparency, hardness, and stretchability by using different materials, and can also cut, open holes, and roughen the surface. processing etc. The use of the auxiliary mold includes providing attachment for packaged or unpackaged three-dimensional flexible circuits, fixing the area to be treated, carrying various exogenous sensitive or targeted drugs, etc., and its overall shape can be face, head, neck, etc. , arms, legs, chest, waist, abdomen, back, buttocks, hands, feet, fingers, toes, shoulders, elbows, wrists, hips, knees, ankles, spine, pelvis, external genitalia, etc. Fixed appliances to meet the auxiliary needs of surface treatment. The exogenous sensitive or targeted drugs include body surface covering, smearing, injection, inhalation or oral drugs, which can respond to the action of the treatment unit covering the area to be treated to adjust its permeability, absorption sex, aggregation, drug activity, or targeting to a specific target of action. The treatment can be regulated by combining conformal auxiliary molds and various exogenous sensitive or targeted drugs.
可选地，在本发明基于液态金属的适形化体表治疗系统的另一实施例中，所述液态金属三维柔性电路印制装置，用于先将所述三维柔性电路印制于所述辅助模具，后将所述辅助模具附着于所述待治疗区域相应的体表或者先将所述三维柔性电路封装于柔性基底，然后将所述柔性基底侧附着于所述辅助模具，最后将所述辅助模具附着于所述待治疗区域相应的体表。Optionally, in another embodiment of the liquid metal-based conformal body surface treatment system of the present invention, the liquid metal three-dimensional flexible circuit printing device is used to first print the three-dimensional flexible circuit on the Auxiliary mold, then attach the auxiliary mold to the corresponding body surface of the area to be treated or first package the three-dimensional flexible circuit in a flexible substrate, then attach the flexible substrate side to the auxiliary mold, and finally place the The auxiliary mold is attached to the corresponding body surface of the area to be treated.
可选地，在本发明基于液态金属的适形化体表治疗系统的另一实施例中，所述液态金属材料包括镓或铟、锡、锌、铋、银、铝中的至少一种金属与镓组成的合金。Optionally, in another embodiment of the liquid metal-based conformal body surface treatment system of the present invention, the liquid metal material includes gallium or at least one metal among indium, tin, zinc, bismuth, silver, and aluminum Alloys with gallium.
可选地，在本发明基于液态金属的适形化体表治疗系统的另一实施例中，所述打印方式包括直写、喷墨、喷涂、涂抹、灌注、转印、化学沉积或置换。Optionally, in another embodiment of the liquid metal-based conformal body surface treatment system of the present invention, the printing method includes direct writing, inkjet, spraying, smearing, perfusion, transfer printing, chemical deposition or replacement.
下面对本发明的具体实施例进行详细说明。Specific embodiments of the present invention will be described in detail below.
图2所示为基于液态金属的适形化体表治疗系统在膝关节热疗方面的应用实施例，其中201为患有风湿或运动损伤的膝关节待治疗区域，202为封装有三维柔性电路的护膝，203为治疗电路中的电热丝加热模块，204为治疗电路中由液态金属直接印制的射频加热线圈模块，205为治疗电路中的热电偶温度监测模块，206为治疗电路中的无线通信模块，207为作为体表三维形貌数据采集和治疗电路控制单元的平板电脑。利用平板电脑207的摄像头，可以对其表面进行多角度扫描，进而通过数据重建，得到膝关节的三维体表形貌数据，并利用液态金属三维柔性电路印制装置和三维模具打印装置，直接打印出具有柔性并封装有三维柔性电路的护膝202；为了对膝关节待治疗区域201进行热疗，护膝202的三维柔性电路中包含有电热丝加热模块203和由液态金属直接印制的射频加热线圈模块204，以实现透过体表对膝关节多个深度层面的热疗，为了监测和调控治疗过程中的组织温度变化，三维柔性电路中还有热电偶温度监测模块205、无线通信模块206，以及同时作为治疗电路控制单元和三维体表形貌数据采集装置的平板电脑，从而实现对膝关节的适形化体表热疗，还可以通过平板电脑监测治疗进度或效果，并及时调整温度设置或加热区域、深度。Fig. 2 shows the application example of the conformable body surface treatment system based on liquid metal in knee joint hyperthermia, wherein 201 is the area to be treated of the knee joint suffering from rheumatism or sports injury, and 202 is the packaged three-dimensional flexible circuit Knee pad, 203 is the heating wire heating module in the treatment circuit, 204 is the radio frequency heating coil module directly printed by liquid metal in the treatment circuit, 205 is the thermocouple temperature monitoring module in the treatment circuit, 206 is the wireless communication in the treatment circuit Module 207 is a tablet computer as a control unit for body surface three-dimensional topography data collection and treatment circuits. Using the camera of the tablet computer 207, the surface can be scanned from multiple angles, and then through data reconstruction, the three-dimensional body surface topography data of the knee joint can be obtained, and the liquid metal three-dimensional flexible circuit printing device and the three-dimensional mold printing device can be used to directly print A knee pad 202 that is flexible and encapsulated with a three-dimensional flexible circuit is produced; in order to perform thermal therapy on the area 201 of the knee joint to be treated, the three-dimensional flexible circuit of the knee pad 202 includes an electric heating wire heating module 203 and a radio frequency heating coil directly printed by liquid metal Module 204, in order to realize the hyperthermia of the knee joint at multiple depth levels through the body surface, in order to monitor and regulate tissue temperature changes during the treatment process, there are thermocouple temperature monitoring module 205 and wireless communication module 206 in the three-dimensional flexible circuit, As well as a tablet computer as a treatment circuit control unit and a three-dimensional body surface topography data acquisition device at the same time, so as to realize conformal body surface hyperthermia for the knee joint, and monitor the progress or effect of treatment through the tablet computer, and adjust the temperature setting in time Or heating area, depth.
图3所示为基于液态金属的适形化体表治疗系统在面部光疗及化学药物治疗方面的应用实施例，其中301为面部待治疗区域，302为单色可见光LED，并组成阵列，303为光敏感治疗药物，并组成阵列，304为由三维模具打印装置印制出的面部适形化柔性电路的整体，305为监测面部血流变化的传感器，306为设定好治疗方案的嵌入式控制单元，307智能手表，可以根据治疗方案定时通过无线通信向嵌入式控制单元306发送指令，启动治疗。针对患有色斑、老化或病原体感染等问题的面部待治疗区域301，经过扫描后由三维模具打印装置印制出面部适形化柔性电路的整体304，其中单色可见光LED302能够对皮肤表面损伤和病原进行光动力治疗，并组成阵列，光敏感治疗药物303则直接涂抹在整个治疗电路表面，可以在单色可见光LED302的照射加强或减少特定局部的吸收，提升治疗效果。为了评估治疗的效果，治疗电路中还嵌入了一个皮肤血液情况监测的传感器305，以及一个用于对整个电路的治疗行为进行调控的嵌入式控制单元306，其可以与智能手表307相连，这样就可以进行时间设置，使治疗在夜间睡眠等特定时间被自动启动。Fig. 3 shows the application example of the conformal body surface treatment system based on liquid metal in facial phototherapy and chemical drug treatment, wherein 301 is the area to be treated on the face, 302 is a monochromatic visible light LED, and forms an array, and 303 is Light-sensitive therapeutic drugs, and form an array, 304 is the whole of the facial conformal flexible circuit printed by the three-dimensional mold printing device, 305 is the sensor for monitoring the change of facial blood flow, 306 is the embedded control for setting the treatment plan The unit, 307 smart watch, can regularly send instructions to the embedded control unit 306 through wireless communication according to the treatment plan to start the treatment. Aiming at the area 301 of the face to be treated with problems such as pigmentation, aging or pathogen infection, after scanning, the whole face conformal flexible circuit 304 is printed by the three-dimensional mold printing device, in which the monochromatic visible light LED 302 can damage the skin surface Perform photodynamic therapy with pathogens and form an array, and the photosensitive therapeutic drug 303 is directly applied on the surface of the entire therapeutic circuit, which can enhance or reduce specific local absorption under the irradiation of monochromatic visible light LED 302 to improve the therapeutic effect. In order to evaluate the effect of treatment, a sensor 305 for monitoring skin and blood conditions is also embedded in the treatment circuit, and an embedded control unit 306 for regulating the treatment behavior of the entire circuit, which can be connected with a smart watch 307, so that The time can be set so that the treatment is automatically started at a specific time such as sleeping at night.
图4所示为基于液态金属的适形化体表治疗系统在颈、肩、背被电刺激治疗方面的应用实施例，其中401为颈、肩、背部待治疗体表区域，402为由三维模具打印装置印制出的适形化柔性电路的整体，403为液态金属印制的肌电信号采集的电极，404为脉冲刺激电极，405为控制单元，406为与控制单元405通过有线方式连接的计算机。针对患有疼痛、僵硬等问题的颈、背、肩待治疗区域401，经过体表扫描与辅助模具的三维打印，制作出三维柔性电路402，其中三维柔性电路402包括由液态金属直接印制的肌电采集电极403，以及治疗电极404，所述治疗电极404用以产生直流或交流电磁波或脉冲，实现对疼痛、僵硬等症状的缓解。电路的运行和通信都由控制单元405执行，并且可以通过有线的方式与控制电脑406相连，以获取更加全面的待治疗体表区域的信息，以及对电刺激治疗进行更精细的调控。Fig. 4 shows the application example of the conformal body surface treatment system based on liquid metal in the treatment of the neck, shoulders, and back by electric stimulation, wherein 401 is the body surface area to be treated on the neck, shoulders, and back, and 402 is the body surface area to be treated by the three-dimensional The whole conformable flexible circuit printed by the mold printing device, 403 is the electrode for collecting electromyographic signals printed by liquid metal, 404 is the pulse stimulation electrode, 405 is the control unit, 406 is connected with the control unit 405 by wire computer. For the neck, back, and shoulders to be treated 401 suffering from pain, stiffness, etc., after body surface scanning and 3D printing of auxiliary molds, a 3D flexible circuit 402 is produced, in which the 3D flexible circuit 402 includes a direct printed liquid metal The myoelectric collection electrode 403 and the treatment electrode 404 are used to generate DC or AC electromagnetic waves or pulses to relieve pain, stiffness and other symptoms. The operation and communication of the circuit are executed by the control unit 405, and can be connected with the control computer 406 by wire to obtain more comprehensive information on the body surface area to be treated and finer regulation of the electrical stimulation therapy.
本发明具有如下优点：The present invention has the following advantages:
1、可以根据受治疗者的待治疗体表区域形貌进行适形化的治疗，并且可以结合待治疗对象的特点，单独或组合使用合适的检测单元、治疗单元和药物，实现体表治疗的定制化和精细化；1. Conformal treatment can be carried out according to the appearance of the subject's body surface area to be treated, and in combination with the characteristics of the subject to be treated, appropriate detection units, treatment units and drugs can be used alone or in combination to achieve body surface treatment customization and refinement;
2、液态金属柔性三维电路的印制，几乎可以覆盖于全身各个体表区域，并且对身体运动具有适应能力，大大拓展了体表治疗的应用范围，提升了治疗的持续性；2. The printing of liquid metal flexible three-dimensional circuits can cover almost every body surface area of the whole body, and has the ability to adapt to body movements, which greatly expands the application range of body surface treatment and improves the continuity of treatment;
3、制作出的适形化三维柔性电路，在工作中可以通过多种设备进行远程监测和人工控制，同时还可以通过对控制算法的调整与改进实现应用的进一步扩展与升级。3. The produced conformal three-dimensional flexible circuit can be remotely monitored and manually controlled by various devices during work, and the application can be further expanded and upgraded by adjusting and improving the control algorithm.
虽然结合附图描述了本发明的实施方式，但是本领域技术人员可以在不脱离本发明的精神和范围的情况下做出各种修改和变型，这样的修改和变型均落入由所附权利要求所限定的范围之内。Although the embodiments of the present invention have been described in conjunction with the accompanying drawings, those skilled in the art can make various modifications and variations without departing from the spirit and scope of the present invention. within the bounds of the requirements.
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