Background technology
Bladder cancer is China's Urology Surgery clinically one of modal tumor, is a kind of disease of direct threat survival of patients
Disease, sickness rate is presented growth trend year by year, and radical cystectomy is recurrent, multiple and invasive bladder cancer mark
Quasi- treatment;And radical prostatectomy is to cure one of localized prostate cancer most efficient method, the key of operation and
Difficult point be all be lower urinary tract reconstruction, i.e. the identical key technical problem of vesicourethral.At present more using the sides of manual suture
Method, but because anastomotic stoma is located at pelvic cavity bottom, position depth, working place is narrow and small, there is suturing skill difficulty greatly, and operation is time-consuming
Long, match result is difficult to ensure that, is susceptible to a series of problem of complication such as urine fistula or anastomotic stricture.Many scholars are to wing
Guang-urethra anastomosis technology is improved and improved, but actual effect all can not be fully up to expectations, it is impossible to promoted completely and specification
Change.
As shown in figure 1, it is shown the structural representation of bladder and urethra link position, need in Fig. 1 during operation
The Partial Resection of bladder 10 and urethra 20 connection shown in circle.Bladder 10 and urethra 20 after excision, shown in circle
Connection this portion of tissue be in off-state, need by anastomosis operation by bladder 10 together with the apical stitch of urethra 20 until
It is allowed to heal.Shown in Figure 13, it is shown that bladder and urethra make arrangements for surgery the internal anatomy of connection.
At present, anastomat is had been widely used in gastrointestinal surgery, vascular surgery, with operating time is shortened, is reduced
Tissue injury, reduce bleeding, the characteristics of match result is good.But urethra tube chamber is little, urethra breaks because lower urinary tract reconstruction operations are present
Hold short, anastomotic stoma to there are problems that tension force, anastomosis staple may induce, up to the present, wing can not still be carried out both at home and abroad
The commercialization apparatus of Guang urethra anastomosis, existing patented technology is that per urethra inserts anastomat, but urethra internal diameter is elongated, to identical
The actual production of device and using high requirement is proposed, not yet has at present product to come out.
This section of urethra 20 of the lower section of bladder 10 is very short, and in basin bottom, position is very narrow, it is impossible to by the residual of urethra 20
End pulls up and is sutured with bladder 10.Need to pull down in bladder 10, bladder 10 is sewn on the stump of urethra 20.Operation technique
When, even bladder 10 is pulled down being sutured all highly difficult with the stump of urethra 20.
At present the anastomosis operation of bladder and urethra is to aid in what is carried out by way of bladder creating-fistula.As shown in Fig. 2 its
It is shown that a kind of operation chart of existing vesicourethral anastomosis operation.After excision, by a urethral catheterization with sacculus 31
Pipe 30 is inserted from urethral orifice, through urethra 20, into bladder 10.Then the opening stitching thread of bladder 10 is banded in into urethral catheterization
The lower end of inflatable or water-filling the sacculus 31 of pipe 30, inflates or water-filling to sacculus 31, struts sacculus 31.After strutting sacculus 31,
Catheter 30 is pulled down, drives bladder 10 to move downward, until the opening of bladder and the stump of urethra 20 are tightly fitted shape
Into matching surface, conventional anastomosis operation is can be carried out afterwards.After anastomosis operation, the holding inflated condition of sacculus 31 (or fill nothing
Bacterium water state), the state being close together by the holding bladder 10 of sacculus 31 and the stump drawing of urethra 20 makes anastomotic stoma naturally raw
It is long, just heal within about 2 weeks.Deng matching surface the healing of bladder end and urethral orifice end together with after, be evacuated (or drawing water) to sacculus 31,
Sacculus 31 shrinks, and then extracts catheter 30.Urination during this is completed by catheter 30.It is related in above-mentioned prior art
Catheter is routine techniquess, may refer to the existing knot of the B2 of US 8083804, the A of CN 1993083 and CN 102639069 A
Structure is understood.
The problem that above-mentioned existing vesicourethral anastomosis operation is present is after operation, to need the sacculus by catheter 30
31 holding bladders 10 and the stump drawing of urethra 20 are close together growth, and the straight cutting of client need one catheter 30 and hangs urinal
2 weeks, urinate and take action and be very inconvenient, be unfavorable for the recovery of patient's bladder and urinary tract organisms' function, also affect attractive in appearance.
The content of the invention
The technical problem to be solved in the present invention is to provide a kind of disintegratable vesicourethral anastomat, before being reduced or avoided
The problem being previously mentioned, particularly shortens the use time of catheter.
Specifically, the invention provides a kind of disintegratable vesicourethral anastomat, in bladder and urethra anastomosis handss
During art, bladder is grown together with the tension of urethra stump, solution pelvic cavity working place is narrow and small, coincideing, difficulty is big to ask
Topic, shortens operating time, shortens the use time of catheter, mitigates the painful and inconvenience of patient, preferably recovers urinary function.
To solve above-mentioned technical problem, the present invention proposes a kind of disintegratable vesicourethral anastomat, for vesicourethral
Bladder and urethra stump are tensed in anastomosing surgical procedure is coincide, wherein, the anastomat is connected including one with the bladder
Annulus, the annulus is provided with multiple hook feet for extending downwardly being connected with the urethra, the end of each hook foot
End is provided with an agnail upwards for hooking the urethra.
Preferably, the anastomat is processed into by Biodegradable material or the material modified of Biodegradable material.
Preferably, the annulus periphery is provided with multiple spikes for hooking the bladder downwards.
Preferably, each described hook foot includes bend inwards section and the bent outward trisection being connected with each other, described inside
Bending segment top is connected with the annulus, and bottom is connected with the bent outward trisection, the bottom of the bent outward trisection with it is described
Agnail connects.
Preferably, the annulus is formed by connecting by the different thick rod of diameter and thin rod interval, the spike and the hook foot
It is connected with the thick rod.Preferably, the annulus is surrounded by the consistent solid barred body of diameter.
Preferably, there is the breach of a disconnection on the annulus.
Preferably, the breach is located between two adjacent thick rods.
Preferably, it is connected with reinforcing connector between the hook foot.
Preferably, from the annulus, downwards outside extends the spike, the folder of the spike and the plane of the annulus
Angle α is 0-90 degree.
Preferably, the angle β bent inwards between section and bent outward trisection is 90-180 degree.
The above-mentioned anastomat of the present invention can respectively hook bladder and urethra stump, by wing by anastomat annulus and agnail
Guang shortens the use time of catheter together with tensing and coincide with urethra stump, alleviates the painful and inconvenience of patient, improves
The quality of anastomotic stoma and recover the urinary function of bladder and urethra as early as possible.
Specific embodiment
In order to be more clearly understood to the technical characteristic of the present invention, purpose and effect, now control illustrates this
Bright specific embodiment.Wherein, identical part adopts identical label.
The just defect of prior art as described in the background section, the invention provides a kind of disintegratable vesicourethral coincide
Device, in the operation process of bladder or prostatosis etc, by bladder tense with urethra stump together with grow, it is and existing
Some reconstruction of urethra are compared, and greatly reduce the labor intensity of suture difficulty and doctor, shorten the use time of catheter, are subtracted
The painful and inconvenience of hypopathia people, is more beneficial for patient and recovers urinary function.
Concrete operative process may refer to shown in Fig. 3-4, wherein, Fig. 3 is shown a tool of the invention
The operation chart of the vesicourethral anastomosis operation of body embodiment;Fig. 4 is shown the urinary urine bladder after anastomosis operation shown in Fig. 3
Pipeline connecting structure schematic diagram.As illustrated, the operating process of the vesicourethral anastomosis operation of the present invention is as follows:
It is same as the prior art, first or the part that the bladder 10 and urethra 20 in Fig. 1 shown in circle connects is cut
Remove.After excision, it is still desirable to using the catheter 30 with sacculus.The per urethra 20 of catheter 30 is entered into bladder 10.
Afterwards, at the stomach wall opening from operation process, using laparoscopic instrument by the present invention a disintegratable bladder
Urethral anastomotic tool 40 (concrete structure is subsequently illustrated) sends into bladder 10.
Then anastomat 40 is enclosed within catheter 30, lower section of the anastomat 40 in sacculus 31, as shown in Figure 3.By wing
The opening stitching thread of Guang 10 is banded in the upper end outside of anastomat 40, and the opening for making bladder 10 wraps anastomat 40
Upper end.
Followed by, inflation struts the sacculus 31 of catheter 30, pulls downward on catheter 30, and bladder and urethra stump are close to
Conventional anastomosis operation is carried out on matching surface, meanwhile, make together with anastomat 40 respectively links up with bladder 10 with urethra 20, to pass through
Anastomat 40 grows bladder together with the tension of urethra stump.Operation can just extract catheter 30 after 3 days, allow anastomat 40
Remain there and play the effect for tensing bladder 10 and urethra 20, allow anastomotic stoma to grow naturally, heal after about 2 weeks, such as Fig. 4 institutes
Show.In a specific embodiment, anastomat 40 can be processed into by Biodegradable material, using rear voluntarily disintegrate in 2 weeks
Into fritter, excreted with urine by urethra.The material can be Biodegradable material, including but not limited to dioxy
The blending of Ketohexamethylene, Acetic acid, hydroxy-, bimol. cyclic ester, lactide, caprolactone, the homopolymer of trimethylene carbonate, copolymer or more polymer
Thing, certainly the material can also be the material modified etc. of Biodegradable material.
Can be seen that from the above-mentioned operative process of the present invention by the present invention in that with anastomat 40, although in operation
Upper still needing uses catheter 30, but for patient, catheter 30 only needs to holding 3 days just can be with the time of 3 days
Acted on downwards using the gravity of catheter 30, anastomat 40 is firmly hooked into bladder 10 and urethra 20, the task of catheter 30 is just
Complete, then can just extract catheter 30.Under the fixation of anastomat 40, meeting nature is healed for bladder 10 and urethra 20
Close.The internal channel of anastomat 40 can allow patient's normal voiding, it is not required that the negative pressure of catheter 30.Shorten catheter 30
Use time, alleviates the painful and inconvenience of patient.Certainly sometimes for insurance for the sake of, postoperative retention catheterization pipe always is played
Drainage of urine is acted on, and until anastomotic healing, so can also.Do so does not mutually conflict with advantages of the present invention.
The concrete structure of the vesicourethral anastomat of the present invention is described in detail with reference to the accompanying drawings, as shown in figure 5, its display
Be a specific embodiment of the invention vesicourethral anastomat 40 side view, the vesicourethral anastomat 40
Can be used to tense the stump of bladder 10 and urethra 20 in vesicourethral anastomosing surgical procedure and coincide.
As illustrated, the overall structure of vesicourethral anastomat 40 of the present invention looks like " stool " of a tubular, last week
It is an annulus 41, here is the barbed connector 42 arranged around annulus.It is described in the illustrated embodiment of Fig. 5-9,11,12
Barbed connector 42 for multiple " stool foot " shapes hook foot, in the embodiment shown in fig. 10, the barbed connector 42 is to downward
The tubular structure stretched.
Fig. 5 is the side view of symmetrical structure, and wherein the sum of the hook foot of barbed connector 42 is six, the complete phase of structure
It is same and symmetrical.I.e., in the embodiment shown in fig. 5, anastomat 40 includes an annulus 41 being connected with bladder 10, around circle
Ring 41 is provided with the barbed connector 42 for extending downwardly, and the end of barbed connector 42 is provided with the falling upwards for hooking urethra 20
Thorn 421.Barbed connector 42 in embodiment illustrated in fig. 5 be multiple hook feet for extending downwardly being connected with urethra 20, each hook
The end of foot is provided with the agnail 421 upwards of a hook urethra 20.
In a preferred embodiment, corresponding to the position of six hook feet, it is provided with around the periphery of annulus 41 multiple downward
Hook the spike 411 of bladder 10.The quantity of spike 411 is also six i.e. shown in Fig. 5, identical and symmetrical point of structure
Cloth.From annulus 41, downwards outside extends the spike 411, the angle α of the plane of spike 411 and annulus 41 be 0-90 degree (
In embodiment illustrated in fig. 7, spike 411 is in same plane with annulus 41, then angle α is 0 degree).
The use of above-mentioned anastomat 40 i.e. of the invention, actually replaces the effect of catheter sacculus.With identical
Spike 411 and agnail 421 on device annulus 41, hooks respectively bladder and urethra.Spike 411 is responsible for hooking bladder, and agnail 421 is negative
Duty hooks urethra, is acted on by the hook lock of spike 411 and agnail 421, by bladder together with urethra tension, is kept for 2 weeks, bladder
After finishing with urethra healing, anastomat disintegrate is excreted with urine.
In a preferred embodiment, as seen in figs. 5-6, each hook foot may each comprise the section that bends inwards being connected with each other
422 and bent outward trisection 423, the top of the section that bends inwards 422 is connected with annulus 41, and bottom is connected with bent outward trisection 423, to
The bottom of outer bending segment 423 is connected with agnail 421.Wherein, the angle β between the section that bends inwards 422 and bent outward trisection 423 is
90-180 degree.Angle β is actually a kind of special circumstances for 180 degree, i.e., there is no the situation of inflection, as shown in fig. 7, each hook
Foot is all straight no inflection.
In above preferred embodiment, the hook foot of anastomat 40 is by bending inwards section 422 and bent outward trisection 423 is formed
The concave inward structure of " 7 " font, can will be bundled in " 7 " font of anastomat by stitching thread in operation process at bladder opening
At recessed structure.Concave inward structure one be facilitate suture tie up positioning;Two is the lower part of the body of the vesicourethral in human body, by gravity shadow
Ring, tissue here has inside stress, will inwardly extrude naturally when being organized in growth, and concave inward structure is conducive to group
Knitting nature inward growth prevents anastomat to shrivel.
Certainly, in the structure of the hook foot without inflection shown in Fig. 7, the coupling part of hook foot and annulus 41 there is also one
Concave inward structure, in the barbed connector 42 of the tubular structure shown in Figure 10 and the coupling part of annulus 41 indent is equally existed
Structure, it is also possible to the effect that the concave inward structure shown in Fig. 5 is similar to is reached, certainly, it will be appreciated by those skilled in the art that Fig. 5 institutes
Show by bending inwards section 422 and bent outward trisection 423 forms the concave inward structure of " 7 " font, indent scope is bigger, " 7 " word
The concave inward structure of shape causes the diameter of indent less than the internal diameter of annulus 41, advantageously in suture tie up and organize nature to
Interior growth prevents anastomat to shrivel.
Fig. 6 is shown that the stereochemical structure of the vesicourethral anastomat of another specific embodiment of the invention is illustrated
Figure.Anastomat structure in the embodiment is substantially the same with Fig. 5, from fig. 6 it can be seen that with a disconnection on annulus 41
Breach 414.The annulus 41 of anastomat 40 is designed to the structure for disconnecting, and effect has at 2 points:One is anastomat 40 is had necessarily
Elasticity, slightly radially firmly compression anastomosis device annulus 41, makes anastomat 40 shrink a little, it is convenient from stomach wall it is minimally invasive be open into
Enter, the opening of such stomach wall can also be as far as possible little;Two when be that inflated is strutted, and annulus 41 can be supportted into larger, can
So that the spike 411 on annulus is followed closely more firmly bladder.
The embodiment of the anastomat 40 of the same design with similar breach 414 also has aobvious in Fig. 7,8,10,11,12
Show.For example, in the embodiment shown in fig. 8, breach 414 is designed as the inclined-plane for cooperating, and its advantage is 414 one-tenth inclinations of breach
Shape, when annulus 41 is connected with bladder, bladder is difficult to clamp-on breach 414 from skewed breach 414 so that breach 414
The identical growth of position is smoothed naturally, it is to avoid the generation of mouth leakage, is conducive to quick healing.For another example, in embodiment illustrated in fig. 11
In, breach 414 is designed as the structure that mutually slip is fastened, and after anastomat 40 is installed in place in operation, can be made by extruding
The slip fastening of breach 414 is integral, and breach can be made to close completely, is similar to that after its fastening shown in Fig. 9 without scarce
The form of mouth, can improve structural strength, eliminate anastomotic stoma and clamp-on the hidden danger that breach affects to heal, while the presence of breach can
To facilitate the minimally invasive opening from stomach wall to be squeezed into, the size of minimally invasive opening can be reduced, be conducive to the healing being open, be mitigated and suffer from
Person's pain.
Certainly, in another specific embodiment, the annulus 41 of anastomat 40 can also be configured without the form of breach,
As shown in figure 9, it is shown that the stereochemical structure of the vesicourethral anastomat of another specific embodiment of the invention is shown
It is intended to.Do not have structural strength jaggy better, it is not easy to fracture.
Further, in a further advantageous embodiment, from Fig. 5-6 as can be seen that the annulus 41 of the present invention can be by straight
The different thick rod 412 in footpath and the interval of thin rod 413 are formed by connecting, and the benefit of thickness spacing structure can be the volume for reducing material,
It is easy to the position disintegrate from the thin rod 413 of structural weak, and the small volume after disintegrate, it is easy to excrete.It is simultaneously guarantee
Structural strength, preferred spike 411 and hook foot 42 are connected with thick rod 412, i.e., the spike 411 and hook foot 42 of main stress are respectively provided with
On the larger thick rod 412 of structural strength, it is unlikely to that stress is excessive in operative process so that anastomat 40 fractures.Meanwhile,
From fig. 6, it can be seen that it is preferred that breach 414 be located at two adjacent thick rods 412 between, i.e., breach 414 disconnect thin rod be located
At position, breach so can be as far as possible reduced for the weakening of circular ring structure intensity.
In addition, from Fig. 9 it can also be seen that the annulus 41 of the present invention can also be that diameter identical circulus is (no thick
Rod and the structure of thin rod interval connection), can as shown in Figure without breach, it is also possible to which similar previous embodiment is arranged like that
Breach.
Further, Fig. 9 is shown the vertical of the vesicourethral anastomat of another specific embodiment of the invention
Body structural representation, the population structure design of anastomat 40 in figure is substantially the same as in the previous example, and difference is, in figure
Reinforcing connector 415 is connected between hook foot.Reinforce shown in Fig. 9 connector 415 in the latticed agnail 421 for being arranged on hook foot with
On part, effect is the structural strength reinforced between hook foot 42, and stress fractures when preventing that hook foot stress is excessive to be used.Certainly,
In a specific embodiment, described to reinforce the circle annulus that connector 415 be connecting hook foot bottom, its structure is similar to
In the anastomat annulus 41 on top.Anastomat annulus 41 is different by diameter as being as shown in the previous embodiment in figure
Thick rod and thin rod interval are formed by connecting, or diameter identical circulus, can not as shown in Figure have breach,
Previous embodiment can be similar to breach is set like that.
Further, if the latticed reinforcing connector 415 in Fig. 9 further encrypted so that grid
The grid of the reinforcing connector 415 of shape disappears, then embodiment illustrated in fig. 9 can just be formed like the structure shown in Figure 10, i.e.,
Tubular structure has been downwardly extending from the annulus 41 of anastomat 40.Certainly, embodiment illustrated in fig. 10 can also be on annulus 41
With breach 414, and for ease of compression, breach 414 is extended into along the length direction of the barbed connector 42 of tubular structure
Breach.
Further, the anastomat hook for the ease of the present invention is firmly difficult for drop-off, in the embodiment shown in fig. 12, can
To arrange multiple outside agnails 421 along the length direction of barbed connector 42, for example, can be along the tubular structure of Figure 10
The outer surface of barbed connector 42 be covered with agnail 421, it is also possible to along length on each the hook foot shown in Fig. 5,6,8,9,11
Multiple outside agnails 421 are arranged in direction.
In sum, the bladder for connection to be tensed to bladder and urethra in vesicourethral anastomosing surgical procedure of the invention
Urethral anastomotic tool, can have diameter identical annulus, it is possible to have the annulus of thickness interval connection;Can have on annulus
Breach, it is also possible to without breach;There can be latticed reinforcing connector between hook foot, it is possible to have positioned at the ring of bottom
The reinforcing connector of shape, it is also possible to without any reinforcing connector.The anastomat of the said structure of the present invention, can perform the operation
By anastomat annulus and agnail in journey, bladder and urethra are hooked respectively, by bladder together with urethra tension, shorten urethral catheterization
The use time of pipe, alleviates the painful and inconvenience of patient.
It will be appreciated by those skilled in the art that although the present invention is described according to the mode of multiple embodiments,
It is that not each embodiment only includes an independent technical scheme.For the sake of so narration is used for the purpose of understanding in description,
Those skilled in the art should be understood description as an entirety, and by technical scheme involved in each embodiment
Regarding as can be mutually combined into the mode of different embodiments to understand protection scope of the present invention.
Schematically specific embodiment of the invention is the foregoing is only, the scope of the present invention is not limited to.It is any
Those skilled in the art, the equivalent variations made on the premise of the design without departing from the present invention and principle, modification and combination,
The scope of protection of the invention all should be belonged to.