CN106419982A

CN106419982A - Biological absorbable suturing assembly

Info

Publication number: CN106419982A
Application number: CN201510482521.XA
Authority: CN
Inventors: 李胜文; 宋志强; 沈海山
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-08-10
Filing date: 2015-08-10
Publication date: 2017-02-22

Abstract

The invention designs an absorbable suturing assembly capable of suturing a human tissue and organ. The suturing assembly is formed by an absorbable suturing line with line joints and a fixing member, wherein the contour of the absorbable line is similar to a continuously arrayed staples; line joints are arranged on a nail tail end and the nail body corners; the degradable fixing member is in a round disc shape; a groove recessed toward the center is arranged on the fixing member; and the bottom of the groove is in a crack structure. During the use, with a help of a guiding device, after the absorbable suturing line with the line joints passes through the human tissue and the fixing member, the line joints are clamped into the fixing member groove, so the human tissue can be sewed. The suturing assembly can be simply operated and requires less time during the operation and has reliable connection; the biological absorbable suturing assembly has great biological compatibility, causes little damage to tissues, and is suitable for tissue suture of various demands.

Description

A kind of biological absorbable suturing assembly

Technical field

The present invention relates to being used for the biological absorbable suture group that tissue is sutured during a kind of surgical operation Part.

Background technology

In surgical procedures, to stomach, intestinal, urinary system, muscle, blood vessel, esophaguses and subcutaneous tissue When carrying out coincideing Deng histoorgan, often carry out seam using stitching thread or anastomosis staple and coincide.Tradition stitching thread enters Row manual suture, in complex operation, especially laparoscopically surgical operation, under mirror, knot tying techniques difficulty is big, operation Time-consuming, patient's intraoperative hemorrhage and damage chance many, and if suture after knotting not firm, knot get loose after hold Easily cause patient's massive hemorrhage or even threat to life.

Anastomosis staple anastomosed tissue organ has some superiority, and this kind of methods of anastomosis has operation simply, and otch is put down Whole, the advantages of time-consuming short.At present, anastomosis staple is broadly divided into nonabsorable and absorbable anastomosis staple.

How nonabsorable anastomosis staple is obtained by materials such as rustless steel, titanium or titanium alloy, and such material is inertia material Material, such anastomosis staple resides in non-degradable in vivo for a long time or is absorbed by the body, and easily produces foreign body reaction, Cause anastomosed tissue to produce inflammatory reaction or foreign material repulsion reaction, affect patient's post-operative recovery, have one to human body Fixed endanger, separately because such anastomosis staple retains in vivo, carry out after also limit operation in patients special examined such as CT, The demand of MRI etc..

Absorbable anastomosis staple is frequently with macromolecule polymeric material, magnesium and magnesium alloy etc. as raw material.Polyphosphazene polymer Condensation material anastomosis staple degradable in vivo, degraded end-product is usually carbon dioxide and water, to tissue no Evil, has good biocompatibility, but because such material is extremely difficult to intensity and the toughness of metal material, It is to ensure that enough intensity and toughness supply clinical practice, the anastomosis staple nail foot diameter of design at present is all relatively thick, stays It is stored in impact organization healing between tissue.Magnesium and magnesium alloy anastomosis staple are metal class anastomosis staple, can drop in human body Solution, but for controlling such anastomosis staple vivo degradation speed, need to add the materials such as aluminum, rare earth element, by It is recognized with neurotoxicity in aluminium element, rare earth element gathers in vivo and can produce around toxic reaction causes Lesion tissue, therefore the bio-toxicity of such anastomosis staple, carcinogenecity and genetoxic letter are treated to study further.

Content of the invention

Not enough for making up traditional suturing thread and anastomosis staple, the present invention provides a kind of seriality to can absorb suturing assembly, This suturing assembly is simple to operate, simplifies stitching thread knot tying techniques, can shorten operating time, sewing effect is more Firm, beneficial to organization healing after suture and ensure successful surgery, stitching thread and the equal degradable of fixture material, Good biocompatibility, no sequel it is adaptable to straight line stitching instrument, curve suture and ring-type suture etc. all kinds Suture.

Total technology design of the present invention is：Using the absorbable suture of current wide clinical application with can drop Solution macromolecule polymeric material makes suturing assembly, after when using, band knot stitching thread passes through tissue, continues Continue through fixture, blocked after knot by fixture, formed by the class " U " of absorbable thread and fixture self-locking Shape ring road, thus realize the suture of tissue.

The technical solution adopted in the present invention is：This suturing assembly includes absorbable suture and degradable is fixed Part；It is structurally characterized in that stitching thread is furnished with knot by suture needle distance, its profile similar to anastomosis staple side by side outside Shape (corner and head end all have knot)；Degradable fixture is provided with the card matching with stitching thread knot size Groove.

Described stitching thread is absorbable suture, its material and now clinical widely used absorbable suture one Cause.It is similar to continuous staple, two " nail " lower limb tip is knot structure, and size is about outside described stitching thread 0.5mm～1.5mm, nail leg root " followed closely " by two stitching thread also has knot to fix.

Described fixture is generally discoid, has a groove to extend from disk mediad side, in the middle of groove is One crack.Fixture cross-sectional diameter is 4～5mm, and highly for 2mm, fixture groove is triangular pyramid, Base is located at fixture center, and width is 0.5～1.5mm, depth about 1mm, and in groove, crack is by fixture Center extends to disk border, blocks knot after passing through for band knot absorbable suture.

The present invention has positive effect：(1) fixture of the present invention adopts Poly(D,L-lactide-co-glycolide (PLGA) it is prepared for material, the final catabolite of this material is lactic acid and hydroxyacetic acid, to human body no Toxic and side effects, can adjust its vivo degradation speed of each copolymer burden control in material simultaneously, thus according to facing Bed needs to adjust fixture degradation time, to ensure that suturing organization healing needs and do not affect tissue growth.(2) Absorbable thread of the present invention adopts clinical at present widely used absorbable thread, safe and reliable and nontoxic to human body Side effect.(3) fixture of the present invention is mated with stitching thread knot, realizes group by both tight fits The reliability suture knitted.After inventive suture knot passes through and organizes and pass through fixture crack, by fixture Knot is blocked in crack, and knot is stayed in fixture groove, has auto-lock function, can prevent stitching thread with Fixture disengages, and effectively ensures the firm suture of tissue.(4) after using suturing assembly of the present invention, fixing Part is located at outside tissue, and only absorbable suture resides in tissue, greatly reduces absorbable material degraded The impact to organization healing of product and residual；Because absorbable suture is thinner compared with other anastomosis staples nail foot, make Also more reduce the damage to tissue with the present invention.(5) after using suturing assembly suture of the present invention, finally can shape Becoming class " U " type, class "O" ring road constraint loop inner tissue will not being formed it is ensured that suturing histotrophic nutrition blood The good micro-environmental state of the unobstructed and suture mouth of pipe, is more beneficial for suturing the healing of tissue.(6) present invention The continuous of stitching thread suture can not only be had according to the suturing assembly needing composition random length of suture tissue Property, have the certainty that anastomosis staple coincide concurrently simultaneously.(7) agent structure of the present invention is stitching thread, can carry out straight Linear slit conjunction, curve suture and tubular stitch etc., therefore present invention can be suitably applied to any type of tissue apposition.

Brief description

Fig. 1 is band knot absorbable suture

Fig. 2 is absorbable fixture

Fig. 3 is that stitching thread knot top view fixed by fixture

Fig. 4 is that stitching thread knot side view fixed by fixture

Fig. 5 is that band knot absorbable suture and fixture complete to suture schematic diagram through after tissue

In each accompanying drawing：1st, stitching thread knot；2nd, absorbable suture；3rd, fixture；4th, fixture groove；5、 Tissue.

Specific implementation method

In FIG, absorbable suture can adopt the material preparation of present wide clinical application, and its knot can In stitching thread preparation process, it is obtained by weaving.Wherein knot 1 diameter about 0.5mm～1.5mm, Absorbable suture 2 forms " stapler pin structure " by knot, and its " nail foot " length is about 3.5mm～5.5mm, Between two " nail feet ", suture length is about 6.0mm～10.0mm.

In fig. 2, fixture adopts PLGA material to prepare, shown in mold shape wherein used and Fig. 2 Fixture shape corresponding, during concrete operations, can using injection method, will PLGA heating melting Afterwards, using the injecting method with certain pressure, the raw material melting is added in mould, then wait PLGA Curing and demolding obtains, and the crack in fixture groove can be cut by cutting knife.

Still see Fig. 2, fixture generally disc-shaped structure 3, there is a groove 4 to extend from disk mediad side, It is a crack in the middle of groove.Fixture cross-sectional diameter is 4～5mm, highly for 2mm, fixture groove For triangular pyramid, base is 0.5～1.5mm positioned at fixture center, width, and depth about 1mm, in groove Crack extends to disk border by fixture center.

In Fig. 3, Fig. 4, Fig. 5, dot spacing is penetrated from selection different length according to tissue thickness and two Band knot absorbable thread, help it to pass through anastomosed tissue 5 and fixture groove by particular pilot device, and After withdraw from guide, because of tissue elasticity, to returning tractive, absorbable thread knot is stuck in solid absorbable suture Determine can not return in part groove, thus reaching self-locking state, simultaneously because anchor designs are fluted, knot Landing to fixture center is difficult (Fig. 4), thus completing tissue apposition, now absorbable suture line Knot and fixture are located at tissue side, and only absorbable suture is located in tissue (Fig. 5).

Claims

1. a kind of absorbability suturing assembly, has the fixture of the absorbable suture with knot and degradable, its Feature is：Absorbable suture is furnished with knot by suture needle distance, and its profile is similar to anastomosis staple profile side by side (corner and head end all have knot)；Fixture is discoid, and disk has a groove to central concave, recessed Trench bottom has a crack to pass through for stitching thread knot.

2. absorbable suturing assembly according to claim 1, is characterized in that：Absorbable suture outward appearance is similar to " staple " structure, at " nail foot " and " nail body ", all there is knot in corner.

3. absorbable suturing assembly according to claim 1, is characterized in that：Fixture is disc-shaped structure, Disk has a groove to central concave, and bottom portion of groove is fissured structure.

4. absorbable suturing assembly according to claims 1 to 3, is characterized in that：1 band knot can absorb seam Zygonema and 2 fixtures are a suturing assembly unit.