CN106579364A - Health food with functions of enhancing immunity and relieving physical fatigue and preparation method of health food - Google Patents

Health food with functions of enhancing immunity and relieving physical fatigue and preparation method of health food Download PDF

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Publication number
CN106579364A
CN106579364A CN201611196837.3A CN201611196837A CN106579364A CN 106579364 A CN106579364 A CN 106579364A CN 201611196837 A CN201611196837 A CN 201611196837A CN 106579364 A CN106579364 A CN 106579364A
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China
Prior art keywords
fermented cordyceps
weight portion
oviductus ranae
health food
cordyceps powder
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Application number
CN201611196837.3A
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Chinese (zh)
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CN106579364B (en
Inventor
郭伟
余宣
杨明
何平清
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Jiangxi Jinshuibao Pharmaceutical Co.,Ltd.
Jiangxi Jimin Kexin Pharmaceutical Co Ltd
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JIANGXI JIMIN KEXIN JINSHUIBAO PHARMACEUTICAL CO Ltd
Jiangxi Jimin Kexin Pharmaceutical Co Ltd
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Priority to CN201611196837.3A priority Critical patent/CN106579364B/en
Publication of CN106579364A publication Critical patent/CN106579364A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
    • A61K36/068Cordyceps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/65Amphibians, e.g. toads, frogs, salamanders or newts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to the field of pharmaceutical science and particularly relates to health food with functions of enhancing immunity and relieving physical fatigue and a preparation method of the health food. A capsule is prepared from following active pharmaceutical ingredients: 328-333 g of fermented cordyceps sinensis powder, 85-90 g of rana japonica oil, 33-38 g of dextrin and 2-4 g of magnesium stearate.

Description

A kind of enhancing immunity, health food of alleviation muscle power and preparation method thereof
Technical field
The invention belongs to field of medicaments, is related to a kind of health food with enhancing immunity, the physical function of alleviation.
Background technology
With the progress of society, the quickening of people's rhythm of life, the change of living environment, and the pressure of each side are more next Bigger, immunity degradation, fatigable crowd are also more and more, considerably increase sub-health population quantity.World Health Organization (WHO) The prediction sex inventory announced recently is bright, and only the 5% of whole world true health, the population ratio of subhealth state is accounted for 75%, remaining is morbid state, and China's sub-health population is also above 70%, it is seen that hypoimmunity has seriously threatened the mankind's The problems such as health, the progress, expanding economy and the raising of national physique of its meeting remote-effects to society.So increasing Immunity of organisms, alleviating physical fatigue, it is healthy most important to safeguarding;Preventing and treating hypoimmunity is very urgent.
Cordyceps powder is that, from isolated mycelium in the fresh Cordyceps in Qinghai, fermented culture gained is mycelial dry Dry powder, has promotion metabolism, improves myocardial nutrition, strengthens the immunocompetence of human body.
Oviductus Ranae, is commonly called as Oviductus Ranae.Guangdong person " hasma ", is northeast Changbaishan area Rana temporaria chensinensis David (Rana.chensinensis) fallopian tube, with the title for medically having " soft gold ".Contain more thyroid in frog oil Element, trace element, multivitamin, aminoacid, simultaneously containing Oleic acid, linoleic acid, linolenic acid for having specific function to human body etc.. With slow down aging, resisting fatigue, YIN nourishing skin care, immunity of organisms function and anti-stress ability are improved, regulation improves coronary heart disease, mends Kidney benefit essence, nourishing lung-YIN, the effect of sexual function improving.
In order to improve the healthy of hypoimmunity and fatiguability crowd, applicant's exploitation is a while exempting from enhancing The health food of epidemic disease power and function of physical fatigue alleviation is had become needed for health-product market.
The content of the invention
It is an object of the invention to provide a kind of health care food with artifical fermentation cordyceps mycopowder and Oviductus Ranae as primary raw material Product or medicine, the health food or medicine have enhancing immunity, function of relieving physical fatigue.
Health food of the present invention or medicine, are processed into by following raw material and adjuvant:
The weight portion of 330 weight portion Oviductus Ranae of fermented Cordyceps powder 85
The weight portion magnesium stearate 1-4 weight portion of dextrin 33
Preferably, health food of the present invention or medicine, are processed into by following raw material and adjuvant:
The weight portion of 330 weight portion Oviductus Ranae of fermented Cordyceps powder 85
The weight portion magnesium stearate 1-3 weight portion of starch 33
Preferably, health food of the present invention or medicine, are processed into by following raw material and adjuvant:
The weight portion of 330 weight portion Oviductus Ranae of fermented Cordyceps powder 85
The weight portion magnesium stearate 1-3 weight portion of Icing Sugar 33
It is further preferred that health food of the present invention or medicine, are processed into by following raw material and adjuvant:
The weight portion of 330 weight portion Oviductus Ranae of fermented Cordyceps powder 85
The weight portion of 33 weight portion magnesium stearate of dextrin 2
Wherein,60Co sterilizings (5KGy) is referred to:For 60Coradiation sterilizing, irradiation dose is 5KGy, i.e., irradiation dose is 5,000 Gray(Gy) (equivalent to 5000 joules/kilogram).
Wherein, fermented Cordyceps powder is fermented Cordyceps powder Cs-4 or fermented Cordyceps powder Cn80.
Wherein, Oviductus Ranae is the mountain Oviductus Ranae of Changbai.
Health food of the present invention or medicine can be prepared into oral formulations, preferably capsule.
Further object is that providing the preparation method of the health food or medicine.
Preparation method of the present invention, comprises the following steps:
By fermented Cordyceps powder Cs-4, Oviductus Ranae elder generation60Co sterilizes (5KGy), then continues at clear production area, Rana amurensis ovary powder The mesh sieve of broken mistake 60, fermented Cordyceps powder Cs-4, dextrin, magnesium stearate cross respectively 60 mesh sieves, weigh by formula ratio, put mixer and mix 30 minutes conjunction time, mixed powder is obtained, mixed powder puts capsule filling machine filling capsule.
Further object is that providing the health food or medicine in enhancing immunity, alleviating physical fatigue side Application in face.
The solution of the present invention is proposed based on following four aspect reason.
Be first fermented Cordyceps powder be, using artificial fermentation method gained, to have formed industrialized production, steady sources, its Chemical composition and pharmacological action are similar to natural cses, will not destroy China's natural resources of Chinese medicinal materials.Another primary raw material of the present invention Using Oviductus Ranae, the effect of with the kidney invigorating and essence nourishing, nourishing YIN and moistening the lung, cough hemoptysis etc. for spiritlessness and weakness, palpitation and insomnia, night sweat, consumptive disease Disease, applicable crowd is wider, is more suitable for health food, more advantage.This formula work(and vital essence replenishing and marrow benifiting, the work(for protecting lung QI invigorating Effect, Jing animal experiments show human peripheral blood as, liver function, renal function and each important organ it is free of toxic effects.
It is an advantage of the current invention that raw material sources economy, stable, formula is reasonable in design, determined curative effect, safe and reliable, has A very wide range of market prospect, input and output are high, and dimensions of market is big, high financial profit.The present invention is with artifical fermentation cordyceps mycopowder and woods Frog oil is primary raw material, and the two produces extraordinary synergy, and effective enhancing immunity, alleviating physical fatigue are obtained non- Normal significant curative effect.
The synergistic function of the present invention is illustrated below by way of experimental data:
Fermented Cordyceps powder Cs-4 (330mg) is irrigated respectively using Kunming mouse;Oviductus Ranae (85mg);Fermentation worm Grass volvatus powder Cs-4 (330mg), Oviductus Ranae (85mg);Test walking weight load, hepatic glycogen content, allergy, carbon are wide within 30 days Data below is drawn clearly:
Data above illustrates that mice perfusion fermented Cordyceps powder Cs-4 (330mg) and Oviductus Ranae (85mg) are significantly stronger than filling Note independent composition fermented Cordyceps powder Cs-4 (330mg), Oviductus Ranae (85mg), draw fermented Cordyceps powder Cs-4 (330mg) and Oviductus Ranae (85mg) drug combination is more efficient, reasonable.
Specific embodiment
By specific examples below, the present invention is further illustrated, but not as the restriction of the present invention.
Embodiment 1:
Raw material (gram) is weighed by following recipe ratios
The Oviductus Ranae 84 of fermented Cordyceps powder Cs-4 331
The magnesium stearate 3 of dextrin 35
Production method is as follows:
First assort supplementary material fermented Cordyceps powder Cs-4, Oviductus Ranae, dextrin, magnesium stearate, by fermented Cordyceps powder Cs-4, Oviductus Ranae elder generation60Co sterilizes (5KGy), and all supplementary materials are proceeded to into clear production area, and Oviductus Ranae crushed 60 mesh sieves, ferment cordyceps sinensis Mycopowder Cs-4, dextrin, magnesium stearate cross respectively 60 mesh sieves, weigh by formula ratio, put mixer incorporation time 30 minutes, must mix Powder, mixed powder puts capsule filling machine filling capsule.
Embodiment 2:
Raw material (kilogram) is weighed by following recipe ratios
The Oviductus Ranae 85 of fermented Cordyceps powder Cn80 332
The magnesium stearate 3 of dextrin 34
Production method is as follows:
First assort supplementary material fermented Cordyceps powder Cn80, Oviductus Ranae, dextrin, magnesium stearate, by fermented Cordyceps powder Cn80, Oviductus Ranae elder generation60Co sterilizes (5KGy), and all supplementary materials are proceeded to into clear production area, and Oviductus Ranae crushed 60 mesh sieves, ferment cordyceps sinensis Mycopowder Cs-4, dextrin, magnesium stearate cross respectively 60 mesh sieves, weigh by formula ratio, put mixer incorporation time 30 minutes, must mix Powder, mixed powder puts capsule filling machine filling capsule.
The recipe determination of embodiment 3, the present invention
(1) carry out from Icing Sugar, starch, three adjuvants of dextrin preferably;
(2) magnesium stearate lubricant consumption is carried out preferably;
Through testing twice preferably, it is determined that the optimum formula of the present invention:
The weight portion of 331 weight portion Oviductus Ranae of fermented Cordyceps powder Cs-4 84
The weight portion of 35 weight portion magnesium stearate of dextrin 2.

Claims (9)

1. a kind of enhancing immunity, the health food of alleviation muscle power or medicine, are processed into by following raw material and adjuvant:
The weight portion of 330 weight portion Oviductus Ranae of fermented Cordyceps powder 85
The weight portion magnesium stearate 1-4 weight portion of dextrin 33.
2. health food according to claim 1 or medicine, are processed into by following raw material and adjuvant:
The weight portion of 330 weight portion Oviductus Ranae of fermented Cordyceps powder 85
The weight portion magnesium stearate 2-3 weight portion of starch 33.
3. health food according to claim 1 or medicine, are processed into by following raw material and adjuvant:
The weight portion of 330 weight portion Oviductus Ranae of fermented Cordyceps powder 85
The weight portion of 33 weight portion magnesium stearate of dextrin 2.
4. health food according to claim 1 or medicine, it is characterised in that fermented Cordyceps powder is fermented Cordyceps powder Cs-4 or fermented Cordyceps powder Cn80.
5. health food according to claim 1 or medicine, it is characterised in that Oviductus Ranae for Changbai the mountain forest frog Oil.
6. health food described in claim 1 or the preparation method of medicine, comprise the following steps:
By fermented Cordyceps powder Cs-4, Oviductus Ranae elder generation60Co sterilizes (5KGy), then continues at clear production area, and Oviductus Ranae was crushed 60 mesh sieves, fermented Cordyceps powder Cs-4, dextrin, magnesium stearate cross respectively 60 mesh sieves, weigh by formula ratio, when putting mixer mixing Between 30 minutes, obtain mixed powder, mixed powder puts capsule filling machine filling capsule.
7. preparation method according to claim 6, comprises the following steps:
Fermented Cordyceps powder Cs-4 331g Oviductus Ranae 84g
Dextrin 35g magnesium stearate 3g
Production method is as follows:
Supplementary material fermented Cordyceps powder Cs-4, Oviductus Ranae, dextrin, magnesium stearate are first assorted, by fermented Cordyceps powder Cs-4, wood frog It is oily first60Co sterilizes (5KGy), and all supplementary materials are proceeded to into clear production area, and Oviductus Ranae crushed 60 mesh sieves, fermented Cordyceps powder Cs-4, dextrin, magnesium stearate cross respectively 60 mesh sieves, weigh by formula ratio, put mixer incorporation time 30 minutes, obtain mixed powder, Mixed powder puts capsule filling machine filling capsule.
8. preparation method according to claim 6, comprises the following steps:
Raw material (kilogram) is weighed by following recipe ratios
The Oviductus Ranae 85 of fermented Cordyceps powder Cn80 332
The magnesium stearate 3 of dextrin 34
Production method is as follows:
Supplementary material fermented Cordyceps powder Cn80, Oviductus Ranae, dextrin, magnesium stearate are first assorted, by fermented Cordyceps powder Cn80, wood frog It is oily first60Co sterilizes (5KGy), and all supplementary materials are proceeded to into clear production area, and Oviductus Ranae crushed 60 mesh sieves, fermented Cordyceps powder Cs-4, dextrin, magnesium stearate cross respectively 60 mesh sieves, weigh by formula ratio, put mixer incorporation time 30 minutes, obtain mixed powder, Mixed powder puts capsule filling machine filling capsule.
9. the application during the health food or medicine described in claim 1 is in terms of enhancing immunity, alleviating physical fatigue.
CN201611196837.3A 2016-12-22 2016-12-22 A kind of strengthen immunity, the health food for alleviating physical strength and preparation method thereof Active CN106579364B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108851030A (en) * 2018-08-24 2018-11-23 江西济民可信药业有限公司 A kind of preparation method for the ergosterol and adenosine dissolution rate improving double capsules that escape

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CN1754557A (en) * 2004-09-29 2006-04-05 李义海 Chinese caterpillar fungus formulation preparation method
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CN105192712A (en) * 2015-09-10 2015-12-30 北京碧延堂生物科技有限公司 Rana japonica oil nutritional food and preparation method thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108851030A (en) * 2018-08-24 2018-11-23 江西济民可信药业有限公司 A kind of preparation method for the ergosterol and adenosine dissolution rate improving double capsules that escape
CN108851030B (en) * 2018-08-24 2021-12-14 江西济民可信药业有限公司 Preparation method for improving dissolution rates of ergosterol and adenosine of Shuangyi capsule

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Address after: 336000 Yuanzhou pharmaceutical industry park, Jiangxi, Yichun

Co-patentee after: Jiangxi Jinshuibao Pharmaceutical Co.,Ltd.

Patentee after: JIANGXI JIMINKEXIN PHARMACEUTICAL Co.,Ltd.

Address before: 336000 Yuanzhou pharmaceutical industry park, Jiangxi, Yichun

Co-patentee before: JIANGXI JIMINKEXIN JINSHUIBAO PHARMACEUTICAL Co.,Ltd.

Patentee before: JIANGXI JIMINKEXIN PHARMACEUTICAL Co.,Ltd.