CN106563047A - Traditional Chinese medicinal feed additive for preventing and treating viral diseases in livestock and preparation method of traditional Chinese medicinal feed additive - Google Patents
Traditional Chinese medicinal feed additive for preventing and treating viral diseases in livestock and preparation method of traditional Chinese medicinal feed additive Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry
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Abstract
The invention belongs to the technical field of research and development of feed additives, and in particular relates to a traditional Chinese medicinal feed additive for preventing and treating viral diseases in livestock and a preparation method of the traditional Chinese medicinal feed additive. The traditional Chinese medicinal feed additive for preventing and treating the viral diseases in the livestock is prepared from the following raw materials in parts by weight: 15-30 parts of cortex fraxini, 15-30 parts of flos chrysanthemi indici, 18-55 parts of herba ephedrae, 10-25 parts of semen ziziphi spinosae, 10-20 parts of radix isatidis, 15-30 parts of fruit of Chinese wolfberry, 10-25 parts of cornus officinalis, 5-12 parts of radix linderae, 9-20 parts of liquorice root and 20-50 parts of rhizoma pinelliae. The traditional Chinese medicinal feed additive for preventing and treating the viral diseases in the livestock provided by the invention, which is prepared by various traditional Chinese medicinal components and makes use of pure traditional Chinese medicinal ingredients, is free from toxic and side effects; and for the viral diseases in the livestock, the traditional Chinese medicinal feed additive can take an effect of inhibiting or killing viruses, and the traditional Chinese medicinal feed additive has good preventing and treating effects.
Description
Technical field
The invention belongs to feed additive research and development technology field, more particularly to a kind of Chinese medicine of preventing and treating animal viral disease
Feed additive and preparation method thereof.
Background technology
Animal viral disease not only serious harm husbandry sector, and some zoonosiss also threaten the mankind and are good for
Health.Because virus is in strict cytozoicus, the disease of intracellular (outward) must optionally be destroyed or suppressed to antiviral drugs
Poison, and to cell, at least cell to being uninfected by does not produce fatal injury.The application of any antiviral chemotherapeutant and
Any method for preventing virus infection, it is necessary to mutually coordinate with the defence function of body itself.
The principle of China's Chinese medicine medical science " righting is got rid of evils ", has correctly pointed out the therapy approach of viral infection, and Chinese herbal medicine is
The powerful mean of motherland's Chinese medicine medical science disease preventing and treating, research has shown that, there is some Chinese herbal medicine suppression to kill the virus or/and adjust body
The effect of immunologic function, can reach the effect for effectively preventing and treating some viral diseases.
The information for being disclosed in the background section is merely intended to increase the understanding of the general background to the present invention, and should not
When the prior art for being considered to recognize or imply in any form the information structure well known to persons skilled in the art.
The content of the invention
For above-mentioned deficiency present in prior art, the present invention provides a kind of Chinese medicine of preventing and treating animal viral disease and raises
Feed additives and preparation method thereof, the feed additive has no toxic side effect, and being added in feedstuff can prevent and treat animal viral disease,
Strengthen the Abwehrkraft des Koepers of poultry.
To achieve these goals, the present invention is to employ the following technical solutions realization：
A kind of Chinese medicine feed additive of preventing and treating animal viral disease, is made up of following raw material by weight：The Qin
Skin 15-30 parts, Flos Chrysanthemi Indici 15-30 parts, Herba Ephedrae 18-55 parts, Semen Ziziphi Spinosae 10-25 parts, Radix Isatidis 10-20 parts, Fructus Lycii 15-30 parts,
Fructus Corni 10-25 parts, Radix Linderae 5-12 parts, Radix Glycyrrhizae 9-20 parts and Rhizoma Pinelliae 20-50 parts.
Preferably, the Chinese medicine feed additive of described preventing and treating animal viral disease, below by weight
Raw material is made：23 parts of Cortex Fraxini, 33 parts of Flos Chrysanthemi Indici, 50 parts of Herba Ephedrae, 18 parts of Semen Ziziphi Spinosae, 18 parts of Radix Isatidis, 28 parts of Fructus Lycii, Fructus Corni 20
45 parts of part, 11 parts of the Radix Linderae, 18 parts of Radix Glycyrrhizae and the Rhizoma Pinelliae.
In addition, present invention also offers the preparation side of the Chinese medicine feed additive of described preventing and treating animal viral disease
Method, comprises the following steps：
(1) each taste medicine is weighed by weight, by Cortex Fraxini, Herba Ephedrae, Radix Isatidis, Fructus Lycii, Fructus Corni, the Radix Linderae, Radix Glycyrrhizae, the Rhizoma Pinelliae
Totally 8 kinds of raw material of Chinese medicine mixing, adds tap water, boiled with high heat after immersion 1-3h, then with slow fire infusion 30-60min after,
Medicinal liquid is poured out, and obtains decocting for Chinese herbal medicine liquid；
(2) powder will be ground into after Flos Chrysanthemi Indici, 2 kinds of raw material of Chinese medicine drying of Semen Ziziphi Spinosae, crosses 60-120 mesh sieves, obtain Chinese medicine powder
End；
(3) by the Chinese medicinal powder mixing obtained by step (1) gained decocting for Chinese herbal medicine liquid and step (2), stir, pass through
Expanded, pelletize is obtained Chinese medicinal granule；
(4) Chinese medicinal granule is pressed into 100g/ bag subpackages, obtains final product the Chinese medicine feed additive of preventing and treating animal viral disease.
Preferably, the addition of tap water is 6-10 times of 12 kinds of raw material of Chinese medicine weight in step (1).
Present invention also offers the using method of the Chinese medicine feed additive of the preventing and treating animal viral disease, is using
When, its addition is the 6-10% of feedstuff gross weight.
Compared with prior art, the present invention has the advantages that：
(1) Chinese medicine feed additive of preventing and treating animal viral disease of the invention compounded by plurality of Chinese component and
Into using pure Chinese medicine composition, having no toxic side effect.
(2) Chinese medicine feed additive of preventing and treating animal viral disease of the invention, for animal viral disease, there is suppression
System kills viral effect, with good prevention and treatment effect.
(3) the Chinese medicine feed additive raw material of preventing and treating animal viral disease of the invention is easy to get, and medicine source is wide, the side of drawing materials
Just, can promote the use of.
Specific embodiment
The specific embodiment of the present invention is described in detail with reference to specific embodiment, it is to be understood that of the invention
Protection domain do not limited by specific embodiment.
Embodiment 1：
A kind of Chinese medicine feed additive of preventing and treating animal viral disease, is made up of following raw material by weight：The Qin
15 parts of skin, 15 parts of Flos Chrysanthemi Indici, 18 parts of Herba Ephedrae, 10 parts of Semen Ziziphi Spinosae, 10 parts of Radix Isatidis, 15 parts of Fructus Lycii, 10 parts of Fructus Corni, 5 parts of the Radix Linderae,
20 parts of 9 parts of Radix Glycyrrhizae and the Rhizoma Pinelliae.
In addition, the preparation method of the Chinese medicine feed additive of described preventing and treating animal viral disease, comprises the following steps：
(1) each taste medicine is weighed by weight, by Cortex Fraxini, Herba Ephedrae, Radix Isatidis, Fructus Lycii, Fructus Corni, the Radix Linderae, Radix Glycyrrhizae, the Rhizoma Pinelliae
Totally 8 kinds of raw material of Chinese medicine mixing, adds tap water, boiled with high heat after immersion 1h, then with slow fire infusion 30min after, medicinal liquid is fallen
Go out, obtain decocting for Chinese herbal medicine liquid；The addition of tap water is 6 times of 12 kinds of raw material of Chinese medicine weight；
(2) powder will be ground into after Flos Chrysanthemi Indici, 2 kinds of raw material of Chinese medicine drying of Semen Ziziphi Spinosae, crosses 60 mesh sieves, obtain Chinese medicinal powder；
(3) by the Chinese medicinal powder mixing obtained by step (1) gained decocting for Chinese herbal medicine liquid and step (2), stir, pass through
Expanded, pelletize is obtained Chinese medicinal granule；
(4) Chinese medicinal granule is pressed into 100g/ bag subpackages, obtains final product the Chinese medicine feed additive of preventing and treating animal viral disease.
Embodiment 2：
A kind of Chinese medicine feed additive of preventing and treating animal viral disease, is made up of following raw material by weight：The Qin
30 parts of skin, 30 parts of Flos Chrysanthemi Indici, 55 parts of Herba Ephedrae, 25 parts of Semen Ziziphi Spinosae, 20 parts of Radix Isatidis, 30 parts of Fructus Lycii, 25 parts of Fructus Corni, the Radix Linderae 12
50 parts of part, 20 parts of Radix Glycyrrhizae and the Rhizoma Pinelliae.
In addition, the preparation method of the Chinese medicine feed additive of described preventing and treating animal viral disease, comprises the following steps：
(1) each taste medicine is weighed by weight, by Cortex Fraxini, Herba Ephedrae, Radix Isatidis, Fructus Lycii, Fructus Corni, the Radix Linderae, Radix Glycyrrhizae, the Rhizoma Pinelliae
Totally 8 kinds of raw material of Chinese medicine mixing, adds tap water, boiled with high heat after immersion 3h, then with slow fire infusion 60min after, medicinal liquid is fallen
Go out, obtain decocting for Chinese herbal medicine liquid；The addition of tap water is 10 times of 12 kinds of raw material of Chinese medicine weight；
(2) powder will be ground into after Flos Chrysanthemi Indici, 2 kinds of raw material of Chinese medicine drying of Semen Ziziphi Spinosae, crosses 120 mesh sieves, obtain Chinese medicinal powder；
(3) by the Chinese medicinal powder mixing obtained by step (1) gained decocting for Chinese herbal medicine liquid and step (2), stir, pass through
Expanded, pelletize is obtained Chinese medicinal granule；
(4) Chinese medicinal granule is pressed into 100g/ bag subpackages, obtains final product the Chinese medicine feed additive of preventing and treating animal viral disease.
Embodiment 3：
A kind of Chinese medicine feed additive of preventing and treating animal viral disease, is made up of following raw material by weight：The Qin
25 parts of skin, 20 parts of Flos Chrysanthemi Indici, 30 parts of Herba Ephedrae, 15 parts of Semen Ziziphi Spinosae, 15 parts of Radix Isatidis, 20 parts of Fructus Lycii, 20 parts of Fructus Corni, the Radix Linderae 10
40 parts of part, 10 parts of Radix Glycyrrhizae and the Rhizoma Pinelliae.
In addition, the preparation method of the Chinese medicine feed additive of described preventing and treating animal viral disease, comprises the following steps：
(1) each taste medicine is weighed by weight, by Cortex Fraxini, Herba Ephedrae, Radix Isatidis, Fructus Lycii, Fructus Corni, the Radix Linderae, Radix Glycyrrhizae, the Rhizoma Pinelliae
Totally 8 kinds of raw material of Chinese medicine mixing, adds tap water, boiled with high heat after immersion 2h, then with slow fire infusion 45min after, medicinal liquid is fallen
Go out, obtain decocting for Chinese herbal medicine liquid；The addition of tap water is 6-10 times of 12 kinds of raw material of Chinese medicine weight；
(2) powder will be ground into after Flos Chrysanthemi Indici, 2 kinds of raw material of Chinese medicine drying of Semen Ziziphi Spinosae, crosses 80 mesh sieves, obtain Chinese medicinal powder；
(3) by the Chinese medicinal powder mixing obtained by step (1) gained decocting for Chinese herbal medicine liquid and step (2), stir, pass through
Expanded, pelletize is obtained Chinese medicinal granule；
(4) Chinese medicinal granule is pressed into 100g/ bag subpackages, obtains final product the Chinese medicine feed additive of preventing and treating animal viral disease.
Embodiment 4：The Chinese medicine feed additive of the preventing and treating animal viral disease of the present invention is in preventing and treating animal viral disease
The test effect of disease
This experimental example detects the performance of embodiment 1-3 gained feed additive with the morbidity chicken of fowl cholera as experimental subject,
Concrete scheme is as follows：
4.1 for examination animal
Cultivation company 45 of Nanning City age in days osmanthus perfume common chicken, it is true through means such as clinical symptoms diagnosis, laboratory diagnosiss
Examine generation avian cholera viral disease.From random choose 250 in diseased chicken group, male and female has concurrently, the heavy and spiritual shape of the chicken individuals selected
State almost, is divided into five groups, 50 per group, average daily body weight, the Average weight increasing a day of every group of chicken is recorded respectively, observes the food of each group chicken
Desire, feed intake, mental status, motion and change of illness state situation are simultaneously recorded.
4.2 using method
Using the positive big shot feedstuff of city's mid-sales chicken, free choice feeding, free water, 6 times a day is fed matched group；Test group
1st, 2,3 implement the Chinese medicine fodder addition for animal viral disease of 1, embodiment 2, the gained of embodiment 3 the present invention respectively
The 8% of the positive big shot feed relative of Ji Ansuowei cities mid-sales chicken is added in the middle of feedstuff, mix homogeneously, by matched group method, i.e., often
Day 6 times, free choice feeding, free water is fed.Continuous feeding 2 months.
4.3 experimental result
Experimental result is as shown in table 1.
The Chinese medicine feed additive clinical trial situation of the preventing and treating animal viral disease of the present invention of table 1
| Group | Cure rate (﹪) | Mortality rate (﹪) | Average weight increasing a day (g) | Feedstuff-meat ratio |
| Matched group | 65 | 35 | 92±10 | 3.6：1 |
| 1 group of embodiment | 83 | 17 | 119±8 | 2.9：1 |
| 2 groups of embodiment | 85 | 15 | 116±8 | 3.0：1 |
| 3 groups of embodiment | 87 | 13 | 122±6 | 2.8：1 |
As shown in Table 1, test group and matched group difference on effect extremely significantly (the P ＜ in terms for the treatment of poultry cholera virus disease
0.01), feed additive of the invention to the cure rate of poultry cholera virus disease more than 80%；Test group recovers fast, appetite
Good, feed intake is big, recovering more afterwards with good facilitation to ill chicken, and the chicken feather color after healing is bright-coloured ruddy, snoozed,
Less physical activities；Test group reaches as high as 30g than matched group Average weight increasing a day, increase rate 32.6%, and difference is extremely notable；Test group 1,
2nd, 3 compared with matched group, and cure rate, Average weight increasing a day all increase significantly, and illustrates that, relative to matched group, test group can be notable
Epidemic disease is prevented and treated, improves poultry body performance, improve the Average weight increasing a day of poultry, improve the production capacity of poultry；Test group is than control
Group efficiency of feed utilization improves 22.2%, and difference is extremely notable, and the best feedstuff-meat ratio of test group reaches 2.8:1, the country has been reached
Advanced level.
It is aforementioned to the present invention specific illustrative embodiment description be in order to illustrate and illustration purpose.These descriptions
It is not wishing to limit the invention to disclosed precise forms, and it will be apparent that according to above-mentioned teaching, can be much changed
And change.The purpose of selecting and describing the exemplary embodiment is that explaining that the certain principles and its reality of the present invention should
With so that those skilled in the art can realize and using the present invention a variety of exemplaries and
A variety of selections and change.The scope of the present invention is intended to be limited by claims and its equivalents.
Claims (4)
1. it is a kind of preventing and treating animal viral disease Chinese medicine feed additive, it is characterised in that by following original by weight
Material is made：Cortex Fraxini 15-30 parts, Flos Chrysanthemi Indici 15-30 parts, Herba Ephedrae 18-55 parts, Semen Ziziphi Spinosae 10-25 parts, Radix Isatidis 10-20 parts, Fructus Lycii
15-30 parts, Fructus Corni 10-25 parts, Radix Linderae 5-12 parts, Radix Glycyrrhizae 9-20 parts and Rhizoma Pinelliae 20-50 parts.
2. it is according to claim 1 preventing and treating animal viral disease Chinese medicine feed additive, it is characterised in that by by weight
The following raw material of amount part ratio is made：23 parts of Cortex Fraxini, 33 parts of Flos Chrysanthemi Indici, 50 parts of Herba Ephedrae, 18 parts of Semen Ziziphi Spinosae, 18 parts of Radix Isatidis, Fructus Lycii
45 parts of 28 parts, 20 parts of Fructus Corni, 11 parts of the Radix Linderae, 18 parts of Radix Glycyrrhizae and the Rhizoma Pinelliae.
3. the preparation method of the Chinese medicine feed additive of preventing and treating animal viral disease according to claim 1 and 2, it is special
Levy and be, comprise the following steps：
(1) each taste medicine is weighed by weight, by Cortex Fraxini, Herba Ephedrae, Radix Isatidis, Fructus Lycii, Fructus Corni, the Radix Linderae, Radix Glycyrrhizae, the Rhizoma Pinelliae totally 8
The mixing of kind of raw material of Chinese medicine, adds tap water, boiled with high heat after immersion 1-3h, then with slow fire infusion 30-60min after, medicinal liquid
Pour out, obtain decocting for Chinese herbal medicine liquid；
(2) powder will be ground into after Flos Chrysanthemi Indici, 2 kinds of raw material of Chinese medicine drying of Semen Ziziphi Spinosae, crosses 60-120 mesh sieves, obtain Chinese medicinal powder；
(3) by the Chinese medicinal powder mixing obtained by step (1) gained decocting for Chinese herbal medicine liquid and step (2), stir, through swollen
Change, pelletize, Chinese medicinal granule is obtained；
(4) Chinese medicinal granule is pressed into 100g/ bag subpackages, obtains final product the Chinese medicine feed additive of preventing and treating animal viral disease.
4. it is according to claim 3 preventing and treating animal viral disease Chinese medicine feed additive preparation method, its feature
It is that the addition of tap water is 6-10 times of 12 kinds of raw material of Chinese medicine weight in step (1).
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101406245A (en) * | 2007-10-10 | 2009-04-15 | 吕良 | Novel feed formula for laying hen containing Chinese medicine |
| CN101455736A (en) * | 2008-12-31 | 2009-06-17 | 中国农业大学 | Wild jujube seeds extract and preparation method and use thereof |
-
2016
- 2016-10-31 CN CN201610965236.8A patent/CN106563047A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101406245A (en) * | 2007-10-10 | 2009-04-15 | 吕良 | Novel feed formula for laying hen containing Chinese medicine |
| CN101455736A (en) * | 2008-12-31 | 2009-06-17 | 中国农业大学 | Wild jujube seeds extract and preparation method and use thereof |
Non-Patent Citations (1)
| Title |
|---|
| 赵凤柱等: "抗病毒中药及其活性成分研究进展", 《实用中医药杂志》 * |
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