CN106551737B - A kind of load medicine equipment protection cover that can disintegrate in vivo - Google Patents
A kind of load medicine equipment protection cover that can disintegrate in vivo Download PDFInfo
- Publication number
- CN106551737B CN106551737B CN201610984596.2A CN201610984596A CN106551737B CN 106551737 B CN106551737 B CN 106551737B CN 201610984596 A CN201610984596 A CN 201610984596A CN 106551737 B CN106551737 B CN 106551737B
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- CN
- China
- Prior art keywords
- distal component
- vivo
- load medicine
- protection cover
- equipment protection
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/04—General characteristics of the apparatus implanted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/12—Blood circulatory system
Abstract
The invention discloses the load medicine equipment protection covers that one kind can disintegrate in vivo comprising the tail end of proximal piece, the proximal piece is connected with distal component, and the tear line of preprocessing is equipped in the distal component.Since the distal component provided by the invention for carrying medicine equipment protection cover is equipped with the tear line of preprocessing, it can be made to swell by Filled Balloon conduit to burst tear line distal component is caused to disintegrate in vivo, so that the load medicine instrument of the load medicine equipment protection cover and carrying is realized quick separating in vivo and is withdrawn from, therefore, the present invention can be used for carrying protection when medicine instrument conveys in vivo, it is fallen off with solving to carry incident drug when medicine instrument conveys in vivo, instrument, which takes off, to be carried and to vascular wall the problems such as scratching damage, and the configuration of the present invention is simple, it is easy to operate, with extremely strong practical value.
Description
Technical field
The present invention is to be related to a kind of load medicine equipment protection cover that can disintegrate in vivo, belongs to the field of medical instrument technology.
Background technique
In recent years, percutaneous coronary intervention (pci) (percutaneous coronary intervention, PCI) takes
Quick development was obtained, but needs for the load medicine instrument such as medicinal balloon, drug stent to be delivered to definitely in interventional procedure
Lesion locations.
Since medicinal balloon is by medication coat in balloon surface, when sacculus reaches diseased region vascular wall be softened,
Expansion, when being contacted with vascular wall inner membrance, the technology of drug quick release, diversion medicaments in local vessel wall, but medicinal balloon
Medication coat loss in crossing process in the blood vessels is still the main problem that current medicinal balloon technology faces.From the number of announcement
According to display, the drug of the prior art passes through loss late all 20% or more, and the design of medicinal balloon is not can avoid to wear at present
It more loses, because of drug and contacting blood that medicinal balloon is exposed, is in addition necessarily caused in crossing process with the friction of blood vessel
Drug is lost.So how medication coat to be protected during transportation, when medicinal balloon being made to reach diseased region work
The problem of being released effectively again, being urgent need to resolve.
In addition, drug stent itself is nonelastic, it is to be delivered to bracket by foley's tube by being mounted on sacculus in advance
At vascular lesion, when balloon expandable is to relying on vascular wall retraction force to be attached at vascular wall after drafting diameter, great advantage is release
When registration, radial support power is stronger, and vascular wall can be close to after expansion, be not easy bounce back and shift.Transportational process in order to prevent
It is middle to destroy, it is required to protection sleeve pipe during the packaging process, drug stent is protected, which is first by drug
Support body compression packs molding then by the protection sleeve pipe of the support body insertion certain specification internal diameter of compression after thermal finalization.But
It is the method has the following shortcomings: medication coat can be because the reason of rubbing, causes drug during installing protection sleeve pipe
Loss, it is this loss it is usually uncontrollable, the stability of technique can be impacted；This friction is for bracket simultaneously
It is also a kind of damage, bracket is caused to be destroyed, the final using effect for influencing product；Furthermore this friction will lead to bracket and ball
The binding ability of capsule itself weakens, and results in bracket and easily slides in transmission process in vivo, the positioning of bracket is caused to be not allowed
Even bracket is wandered causes serious malpractice in vivo.
Also, clinically 70% coronary stenosis Disease has different degrees of Coronary Calcification, blood vessel tortuous and diffusivity
The complex lesions such as lesion, medicinal balloon in transmission process, can rub in vivo with conduit, vascular wall and complex lesions region
So that medication coat falls off, and medication coat fall off certainly will influence therapeutic effect and will lead to intravascular acute embolic and its
The generation of his disease；And drug stent is easy to happen cradling piece and scratches caused blood to vascular wall in vivo in transmission process
Pipe damage, and there is the de- load phenomenon of bracket, and the bracket after de- load is fallen into blood vessel, it will lead to fatal risk.
But it is using the external protection being heat-shrinked before protection sleeve pipe mainly performs the operation to the protection of sacculus or bracket at present
For protection during logistics transportation of sacculus or bracket and the protection of personnel misoperation is prevented, such as: patent
Medicine disclosed in the balloon protective sleeve and CN201520518264 of balloon catheter for expanding vertebra disclosed in CN200920173162
Object FirebirdTM；In surgical procedure, needs first artificial removal protection sleeve pipe and then conveyed in vivo, be can not achieve to internal
The protection of transmission process can not solve drug stent, medicinal balloon etc. and carry the drug that medicine instrument occurs in transmission process in vivo
It falls off, damage and various other security risk problems to blood vessel, becomes intervention operator's urgent need to solve the problem.
Summary of the invention
In view of the above-mentioned problems existing in the prior art, the object of the present invention is to provide the load medicine devices that one kind can disintegrate in vivo
Tool protective case carries protection problem of the medicine instrument in vivo in transmission process to solve drug stent, medicinal balloon etc..
To achieve the above object, the present invention adopts the following technical scheme:
A kind of load medicine equipment protection cover that can disintegrate in vivo, including proximal piece, the tail end connection of the proximal piece
There is distal component, the tear line of preprocessing is equipped in the distal component.
Preferably, the tear line is along the longitudinally disposed of the distal component.
Preferably, the tear line at least one.
As further preferred scheme, the tear line at least two, it is symmetrically arranged in distal component.
Preferably, the distal component is the pipe fitting made of one or more layers high molecular material.
As further preferred scheme, the distal component is elasticity or non-resilient pipe fitting.
As further preferred scheme, the high molecular material be selected from silicon rubber, polyurethane, polytetrafluoroethylene (PTFE), polypropylene,
At least one of polyethylene, nylon, nylon elastomer, polyethylene terephthalate, polyethers.
As further preferred scheme, the outer surface of the distal component is coated with lubricity silicon coating or hydrophilic painting
Layer.
Preferably, the proximal piece is equipped with one or more Marking rings.
Preferably, the load medicine equipment protection cover further includes handle, the head of the handle and the proximal piece
End is connected.
Preferably, the load medicine instrument is that ball expands formula drug stent or medicinal balloon.
Compared to the prior art, the beneficial technical effect of the present invention lies in:
It, can be by filling since the distal component provided by the invention for carrying medicine equipment protection cover is equipped with the tear line of preprocessing
It is full of that foley's tube makes it swell and bursting tear line causes distal component to disintegrate in vivo, so that the load medicine instrument is protected
Sheath and the load medicine instrument of carrying realize quick separating in vivo and withdraw from that therefore, the present invention can be used for carrying medicine instrument in vivo
Protection when conveying, to solve to carry, incident drug falls off, instrument takes off and carries and to vascular wall when medicine instrument conveys in vivo
The problems such as scratching damage, and it is the configuration of the present invention is simple, easy to operate, there is extremely strong practical value, compared with the existing technology
With conspicuousness progress.
Detailed description of the invention
Fig. 1 is the structural schematic diagram for the load medicine equipment protection cover that one kind that embodiment provides can disintegrate in vivo.
Figure label is schematically as follows: 1, handle；2, proximal piece；3, distal component；4, tear line；5, Marking ring.
Specific embodiment
Technical solution of the present invention is done below with reference to drawings and examples and is further clearly and completely described.
Embodiment
The load medicine equipment protection cover that one kind provided in this embodiment can disintegrate in vivo as shown in Figure 1:, including it is handle 1, close
End pieces 2 and distal component 3, the handle 1 are connected with the head end of the proximal piece 2, the tail end of the proximal piece 2 with
Distal component 3 is connected；The tear line 4 of preprocessing is equipped in the distal component 3.
As a preferred solution:
The tear line 4 is longitudinally disposed along the distal component 3；
4 at least one of tear line, preferably at least two；Also, it is best when the tear line 4 at least two
It is symmetricly set in distal component 3；
The distal component 3 is the elasticity made of one or more layers high molecular material or non-resilient pipe fitting.
Above-mentioned design is conducive to the tear line 4 and is smoothly burst in vivo.
The proximal piece 2 can be solid rod piece or hollow pipe fitting, and the material can be metal, alloy or high score
Sub- material.The high molecular material can be selected from silicon rubber, polyurethane, polytetrafluoroethylene (PTFE), polypropylene, polyethylene, nylon, nylon bullet
At least one of property body, polyethylene terephthalate, polyethers.
In addition, the proximal piece 2 is equipped with one or more Marking rings 5, judged during operation in order to doctor described in
Whether the relative position of conveying protective device enters patient's body in vivo specific location and protective case and foley's tube changes.
The outer surface of the distal component 3 can be coated with lubricity silicon coating or hydrophilic coating, to reduce the load
Coefficient of friction of the medicine equipment protection cover in guiding catheter and blood vessel avoids generating damage to blood vessel.
The load medicine instrument can expand formula drug stent or medicinal balloon for ball.
The load medicine equipment protection cover may also include handle 1, and the handle 1 is connected with the head end of the proximal piece 2,
In favor of operation.
It is then close by push by the way that first drug stent or medicinal balloon are packed into the distal component 3 in vitro
End pieces 2 make distal component 3 reach lesions position, then (drug stent is covered on foley's tube by Filled Balloon conduit
Conveying, and medicinal balloon is that only foley's tube does not have bracket), so that foley's tube is swollen to burst and be arranged in distal component 3
On tear line 4, thus cause distal component 3 to disintegrate in vivo and with carry medicine instrument (drug stent or medicinal balloon) mutually separate
And it withdraws from.
In summary as it can be seen that since the distal component provided by the invention for carrying medicine equipment protection cover is equipped with tearing for preprocessing
Line is split, it can be made to swell by Filled Balloon conduit and burst tear line distal component is caused to disintegrate in vivo, so that institute
The load medicine equipment protection cover stated and the load medicine instrument of carrying realize quick separating in vivo and withdraw from that therefore, the present invention can be used for
Protection when medicine instrument conveys in vivo is carried, incident drug falls off, instrument takes off when medicine instrument conveys in vivo to solve to carry
It carries and to vascular wall the problems such as scratching damage, and the configuration of the present invention is simple, easy to operate, there is extremely strong practical value,
There is conspicuousness progress compared with the existing technology.
It is last it is necessarily pointed out that: the foregoing is merely the preferable specific embodiment of the present invention, but the present invention
Protection scope be not limited thereto, anyone skilled in the art in the technical scope disclosed by the present invention,
Any changes or substitutions that can be easily thought of, should be covered by the protection scope of the present invention.
Claims (6)
1. the load medicine equipment protection cover that one kind can disintegrate in vivo, the load medicine instrument is that ball expands formula drug stent or drug ball
Capsule；It is characterized by: the load medicine equipment protection cover is made of handle, proximal piece and distal component, the handle with
The head end of the proximal piece is connected, and the tail end of the proximal piece is connected with distal component, and the proximal piece is real
The rod piece of the heart or hollow pipe fitting, the distal component are the pipe fittings made of one or more layers high molecular material, described remote
End pieces are equipped with the tear line of preprocessing, and the tear line is longitudinally disposed along the distal component；By first will in vitro
Ball expands formula drug stent or medicinal balloon is packed into the distal component, then arrives distal component by pushing proximal piece
Up to lesions position, then by Filled Balloon conduit, foley's tube is set to swell to burst the tear line being arranged in distal component, from
And causes distal component to disintegrate in vivo and mutually separate and withdraw from load medicine instrument.
2. load medicine equipment protection cover according to claim 1, it is characterised in that: the tear line at least one.
3. load medicine equipment protection cover according to claim 2, it is characterised in that: the tear line at least two, right respectively
Claim to be arranged in distal component.
4. load medicine equipment protection cover according to claim 1, it is characterised in that: the distal component is elasticity or non-resilient
Pipe fitting.
5. load medicine equipment protection cover according to claim 1, it is characterised in that: the outer surface of the distal component is coated with
Lubricity silicon coating or hydrophilic coating.
6. load medicine equipment protection cover according to claim 1, it is characterised in that: the proximal piece is equipped with one or more
A Marking ring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610984596.2A CN106551737B (en) | 2016-11-09 | 2016-11-09 | A kind of load medicine equipment protection cover that can disintegrate in vivo |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610984596.2A CN106551737B (en) | 2016-11-09 | 2016-11-09 | A kind of load medicine equipment protection cover that can disintegrate in vivo |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106551737A CN106551737A (en) | 2017-04-05 |
| CN106551737B true CN106551737B (en) | 2019-01-04 |
Family
ID=58444819
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610984596.2A Active CN106551737B (en) | 2016-11-09 | 2016-11-09 | A kind of load medicine equipment protection cover that can disintegrate in vivo |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106551737B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110623779B (en) * | 2018-06-21 | 2023-07-25 | 连新龙 | Protective sleeve for intervention |
| CN109846583A (en) * | 2019-03-27 | 2019-06-07 | 吴忠隐 | A kind of aortic stents window controlling system |
| CN110681033A (en) * | 2019-10-18 | 2020-01-14 | 四川海汇药业有限公司 | Balloon protective sleeve and mounting method thereof |
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| US20140052104A1 (en) * | 2011-07-25 | 2014-02-20 | Terumo Kabushiki Kaisha | Treatment device |
| CN104382677A (en) * | 2014-11-10 | 2015-03-04 | 哈尔滨医科大学 | Separable bracket pushing system |
| CN204995980U (en) * | 2015-07-16 | 2016-01-27 | 浙江巴泰医疗科技有限公司 | Drug balloon catheter |
| CN105307716A (en) * | 2013-05-03 | 2016-02-03 | C·R·巴德公司 | Peelable protective sheath |
| CN105338928A (en) * | 2013-06-21 | 2016-02-17 | 艾博特心血管系统公司 | Protective sheath assembly for a polymer scaffold |
| US9387101B2 (en) * | 2007-10-17 | 2016-07-12 | C.R. Bard, Inc. | Delivery system for a self-expanding device for placement in a bodily lumen |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5196024A (en) * | 1990-07-03 | 1993-03-23 | Cedars-Sinai Medical Center | Balloon catheter with cutting edge |
| DE602006010171D1 (en) * | 2006-02-24 | 2009-12-17 | Nat Univ Ireland | Minimally invasive intravascular treatment device |
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2016
- 2016-11-09 CN CN201610984596.2A patent/CN106551737B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9387101B2 (en) * | 2007-10-17 | 2016-07-12 | C.R. Bard, Inc. | Delivery system for a self-expanding device for placement in a bodily lumen |
| US20140052104A1 (en) * | 2011-07-25 | 2014-02-20 | Terumo Kabushiki Kaisha | Treatment device |
| CN105307716A (en) * | 2013-05-03 | 2016-02-03 | C·R·巴德公司 | Peelable protective sheath |
| CN105338928A (en) * | 2013-06-21 | 2016-02-17 | 艾博特心血管系统公司 | Protective sheath assembly for a polymer scaffold |
| CN104382677A (en) * | 2014-11-10 | 2015-03-04 | 哈尔滨医科大学 | Separable bracket pushing system |
| CN204995980U (en) * | 2015-07-16 | 2016-01-27 | 浙江巴泰医疗科技有限公司 | Drug balloon catheter |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106551737A (en) | 2017-04-05 |
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| TR01 | Transfer of patent right |
Effective date of registration: 20210805 Address after: 215128 plant 3, Shicheng science and Technology Park, 1566 Yinzhong South Road, Wuzhong Economic Development Zone, Suzhou City, Jiangsu Province Patentee after: Sano Shenchang Medical Technology Co.,Ltd. Address before: 201613 3rd floor, building 11, 68 Zhongchuang Road, Songjiang District, Shanghai Patentee before: ENMAI (SHANGHAI) MEDICAL TECHNOLOGY Co.,Ltd. |
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| TR01 | Transfer of patent right |