CN106551737A - A kind of load medicine equipment protection cover that can disintegrate in vivo - Google Patents

A kind of load medicine equipment protection cover that can disintegrate in vivo Download PDF

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Publication number
CN106551737A
CN106551737A CN201610984596.2A CN201610984596A CN106551737A CN 106551737 A CN106551737 A CN 106551737A CN 201610984596 A CN201610984596 A CN 201610984596A CN 106551737 A CN106551737 A CN 106551737A
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CN
China
Prior art keywords
protection cover
equipment protection
medicine equipment
distal component
vivo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201610984596.2A
Other languages
Chinese (zh)
Other versions
CN106551737B (en
Inventor
徐荣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sano Shenchang Medical Technology Co.,Ltd.
Original Assignee
Grace Pulse (shanghai) Medical Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grace Pulse (shanghai) Medical Technology Co Ltd filed Critical Grace Pulse (shanghai) Medical Technology Co Ltd
Priority to CN201610984596.2A priority Critical patent/CN106551737B/en
Publication of CN106551737A publication Critical patent/CN106551737A/en
Application granted granted Critical
Publication of CN106551737B publication Critical patent/CN106551737B/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/105Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/04General characteristics of the apparatus implanted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/12Blood circulatory system

Abstract

The invention discloses a kind of load medicine equipment protection cover that can disintegrate in vivo, which includes proximal piece, and the tail end of the proximal piece is connected with distal component, and the tear line of preprocessing is provided with the distal component.As the distal component for carrying medicine equipment protection cover that the present invention is provided is provided with the tear line of preprocessing, which can be made to swell by Filled Balloon conduit and burst tear line and cause distal component to be disintegrated in vivo, so that described load medicine equipment protection cover is realized sharp separation in vivo with the load medicine apparatus for carrying and is withdrawn from, therefore, the present invention can be used to carry protection when medicine apparatus is conveyed in vivo, come off with solving incident medicine when load medicine apparatus is conveyed in vivo, apparatus take off carry and to blood vessel wall the problems such as scratching damage, and present configuration is simple, it is easy to operate, with extremely strong practical value.

Description

A kind of load medicine equipment protection cover that can disintegrate in vivo
Technical field
The present invention is to be related to a kind of load medicine equipment protection cover that can disintegrate in vivo, belongs to technical field of medical instruments.
Background technology
In recent years, percutaneous coronary intervention (pci) (percutaneous coronary intervention, PCI) takes Quick development was obtained, but needs to be delivered to definitely the load medicine apparatus such as medicinal balloon, drug stent in interventional procedure Lesion locations.
Due to medicinal balloon be by medication coat in balloon surface, when sacculus reaches diseased region blood vessel wall it is softened, Expansion, when contacting with blood vessel wall inner membrance, the technology of medicine quick release, diversion medicaments in local vessel wall, but medicinal balloon Medication coat loss in crossing process in intravascular is still the subject matter that current medicinal balloon technology faces.From the number announced According to display, the medicine of prior art passes through loss rate all more than 20%, and the design of medicinal balloon is cannot to avoid wearing at present More lose, because the exposed medicine of medicinal balloon and contacting blood, the friction in crossing process with blood vessel, necessarily causes in addition Medicine is lost.So how medication coat to be protected in course of conveying, when making medicinal balloon reach diseased region work Effectively discharged again, be the problem of urgent need to resolve.
In addition, drug stent itself is nonelastic, which is by being mounted on sacculus in advance, being delivered to support by foley's tube At vascular lesion, when balloon expandable to draft diameter after be attached at blood vessel wall by blood vessel wall retraction force, great advantage is release When registration, radial support power is stronger, can be close to blood vessel wall, be difficult to bounce back and shift after expansion.In order to prevent transportation It is middle that destruction occurs, it is required to protect sleeve pipe to protect drug stent in packaging process, the guard method is first by medicine Stake body compresses, and then by the protection sleeve pipe of the stake body insertion certain specification internal diameter of compression, molding is packed after thermal finalization.But It is that the method has the disadvantage that:Medication coat can be because the reason for rubbing, causes medicine during protection sleeve pipe is installed Loss, this loss is typically uncontrollable, and the stability of technique can be impacted;This friction is for support simultaneously And a kind of damage, cause support to be destroyed, the final using effect for affecting product;In addition this friction can cause support and ball The binding ability of capsule itself weakens, and result in support and easily occurs to slide in course of conveying in vivo, causes the positioning of support to be forbidden Even support is wandered and causes serious malpractice in vivo.
Also, clinically 70% coronary stenosis Disease has different degrees of Coronary Calcification, blood vessel tortuous and diffusivity The complex lesions such as pathological changes, medicinal balloon in course of conveying, can occur to rub with conduit, blood vessel wall and complex lesions region in vivo So that medication coat comes off, and medication coat come off certainly will affect therapeutic effect and can cause Ink vessel transfusing acute embolic and its The generation of his disease;And drug stent is in vivo in course of conveying, it is susceptible to cradling piece and caused blood is scratched to blood vessel wall Pipe is damaged, and the de- load phenomenon of support occurs, and the support after de- load is fallen in blood vessel, it will cause fatal risk.
But the external protection before protecting protection of the sleeve pipe to sacculus or support mainly to perform the operation using thermal contraction at present, be Protection for sacculus or support during logistics transportation and the protection of personnel's maloperation is prevented, for example:Patent Medicine disclosed in the balloon protective sleeve and CN201520518264 of the balloon catheter for expanding vertebra disclosed in CN200920173162 Thing FirebirdTM;In operation technique, need first manually to remove protection sleeve pipe and then conveyed in vivo, it is impossible to realize to internal The protection of course of conveying, it is impossible to solve drug stent, medicinal balloon etc. and carry the medicine that medicine apparatus occurs in course of conveying in vivo Come off, the damage to blood vessel and other various security risk problems, become intervention operator's urgent need to solve the problem.
The content of the invention
For the problems referred to above that prior art is present, it is an object of the invention to provide a kind of load medicine device that can disintegrate in vivo Tool protective case, carries the protection problem of medicine apparatus in vivo in course of conveying to solve drug stent, medicinal balloon etc..
For achieving the above object, the present invention is adopted the following technical scheme that:
A kind of load medicine equipment protection cover that can disintegrate in vivo, including proximal piece, the tail end connection of the proximal piece There is distal component, the tear line of preprocessing is provided with the distal component.
Preferably, the tear line is along the longitudinally disposed of the distal component.
Preferably, the tear line at least one.
Used as further preferred scheme, the tear line at least two is symmetrically arranged in distal component.
Preferably, the distal component is the pipe fitting by made by one or more layers macromolecular material.
Used as further preferred scheme, the distal component is elastic or non-resilient pipe fitting.
As further preferred scheme, the macromolecular material selected from silicone rubber, polyurethane, politef, polypropylene, At least one in polyethylene, nylon, nylon elastomer, polyethylene terephthalate, polyethers.
Used as further preferred scheme, the outer surface of the distal component is coated with lubricity silicon coating or hydrophilic painting Layer.
Preferably, the proximal piece is provided with one or more Marking rings.
Preferably, the load medicine equipment protection cover also includes handle, the head of the handle and the proximal piece End is connected.
Preferably, the load medicine apparatus is that ball expands formula drug stent or medicinal balloon.
Compared to prior art, the Advantageous Effects of the present invention are:
As the distal component for carrying medicine equipment protection cover that the present invention is provided is provided with the tear line of preprocessing, can be by filling The foley's tube that is full of makes which swell and bursts tear line and cause distal component to be disintegrated in vivo, so that described load medicine apparatus is protected Sheath realizes sharp separation in vivo and withdraws from the load medicine apparatus for carrying, therefore, the present invention can be used to carry medicine apparatus in vivo Protection during conveying, to solve when load medicine apparatus is conveyed in vivo, incident medicine comes off, apparatus takes off and carries and to blood vessel wall The problems such as scratching damage, and present configuration is simple and convenient to operate, with extremely strong practical value, relative to prior art With significance progress.
Description of the drawings
Fig. 1 is a kind of structural representation of load medicine equipment protection cover that can disintegrate in vivo that embodiment is provided.
In figure, label is schematically as follows:1st, handle;2nd, proximal piece;3rd, distal component;4th, tear line;5th, Marking ring.
Specific embodiment
Technical scheme is done below with reference to drawings and Examples and further clearly and completely describe.
Embodiment
As shown in Figure 1:A kind of load medicine equipment protection cover that can disintegrate in vivo that the present embodiment is provided, including it is handle 1, near End pieces 2 and distal component 3, the handle 1 are connected with the head end of the proximal piece 2, the tail end of the proximal piece 2 with Distal component 3 is connected;The tear line 4 of preprocessing is provided with the distal component 3.
Preferably:
The tear line 4 is longitudinally disposed along the distal component 3;
The tear line 4 at least one, with least two preferably;Also, it is when the tear line 4 at least two, best It is symmetricly set in distal component 3;
The distal component 3 is elastic by made by one or more layers macromolecular material or non-resilient pipe fitting.
Above-mentioned design is conducive to the tear line 4 smoothly to be burst in vivo.
The proximal piece 2 can be solid rod member or hollow pipe fitting, and the material can be metal, alloy or high score Sub- material.The macromolecular material may be selected from silicone rubber, polyurethane, politef, polypropylene, polyethylene, nylon, nylon bullet At least one in gonosome, polyethylene terephthalate, polyethers.
In addition, the proximal piece 2 is provided with one or more Marking rings 5, judge described in operation in order to doctor Whether the particular location and the relative position of protective case and foley's tube that conveying protection device is entered in patient's body in vivo changes.
The outer surface of the distal component 3 can be coated with lubricity silicon coating or hydrophilic coating, to reduce described load Coefficient of friction of the medicine equipment protection cover in guiding catheter and blood vessel, it is to avoid damage is produced to blood vessel.
The load medicine apparatus can expand formula drug stent or medicinal balloon for ball.
The load medicine equipment protection cover may also include handle 1, and the handle 1 is connected with the head end of the proximal piece 2, It is beneficial to operation.
It is by first loading drug stent or medicinal balloon in described distal component 3 in vitro, then near by pushing End pieces 2 make distal component 3 reach lesions position, then (drug stent is enclosed within foley's tube by Filled Balloon conduit Conveying, and medicinal balloon is that only foley's tube does not have support), make foley's tube swell distal component 3 is arranged on to burst On tear line 4, so as to cause distal component 3 to be disintegrated in vivo and with carry medicine apparatus (drug stent or medicinal balloon) be separated And withdraw from.
It is visible in sum, as the distal component for carrying medicine equipment protection cover that the present invention is provided is provided with tearing for preprocessing Line is split, which can be made to swell by Filled Balloon conduit and be burst tear line and cause distal component to be disintegrated in vivo, so that institute The load medicine apparatus for carrying medicine equipment protection cover and carrying stated realizes sharp separation in vivo and withdraws from, therefore, the present invention can be used for Protection when medicine apparatus is conveyed in vivo is carried, incident medicine comes off, apparatus takes off to solve when load medicine apparatus is conveyed in vivo Carry and to blood vessel wall the problems such as scratching damage, and present configuration is simple and convenient to operate, with extremely strong practical value, There is significance progress relative to prior art.
Finally be necessary it is pointed out here that be:The foregoing is only the present invention preferably specific embodiment, but the present invention Protection domain be not limited thereto, any those familiar with the art the invention discloses technical scope in, The change or replacement that can be readily occurred in, should all be included within the scope of the present invention.

Claims (10)

1. a kind of load medicine equipment protection cover that can disintegrate in vivo, it is characterised in that:Including proximal piece, the proximal piece Tail end is connected with distal component, and the tear line of preprocessing is provided with the distal component.
It is 2. according to claim 1 to carry medicine equipment protection cover, it is characterised in that:The tear line is along the distal component It is longitudinally disposed.
It is 3. according to claim 1 to carry medicine equipment protection cover, it is characterised in that:The tear line at least one.
It is 4. according to claim 3 to carry medicine equipment protection cover, it is characterised in that:The tear line at least two, it is right respectively Title is arranged in distal component.
It is 5. according to claim 1 to carry medicine equipment protection cover, it is characterised in that:The distal component is by one or more layers Pipe fitting made by macromolecular material.
It is 6. according to claim 5 to carry medicine equipment protection cover, it is characterised in that:The distal component is elastic or non-resilient Pipe fitting.
It is 7. according to claim 5 to carry medicine equipment protection cover, it is characterised in that:The outer surface of the distal component is coated with Lubricity silicon coating or hydrophilic coating.
It is 8. according to claim 1 to carry medicine equipment protection cover, it is characterised in that:The proximal piece is provided with one or many Individual Marking ring.
It is 9. according to any one of claim 1 to 8 to carry medicine equipment protection cover, it is characterised in that:The load medicine apparatus is protected Sheath also includes handle, and the handle is connected with the head end of the proximal piece.
It is 10. according to any one of claim 1 to 8 to carry medicine equipment protection cover, it is characterised in that:It is described load medicine apparatus be Ball expands formula drug stent or medicinal balloon.
CN201610984596.2A 2016-11-09 2016-11-09 A kind of load medicine equipment protection cover that can disintegrate in vivo Active CN106551737B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610984596.2A CN106551737B (en) 2016-11-09 2016-11-09 A kind of load medicine equipment protection cover that can disintegrate in vivo

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610984596.2A CN106551737B (en) 2016-11-09 2016-11-09 A kind of load medicine equipment protection cover that can disintegrate in vivo

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CN106551737A true CN106551737A (en) 2017-04-05
CN106551737B CN106551737B (en) 2019-01-04

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109846583A (en) * 2019-03-27 2019-06-07 吴忠隐 A kind of aortic stents window controlling system
CN110623779A (en) * 2018-06-21 2019-12-31 连新龙 Intervene and use lag
CN110681033A (en) * 2019-10-18 2020-01-14 四川海汇药业有限公司 Balloon protective sleeve and mounting method thereof

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196024A (en) * 1990-07-03 1993-03-23 Cedars-Sinai Medical Center Balloon catheter with cutting edge
CN101420913A (en) * 2006-02-24 2009-04-29 高尔韦爱尔兰国立大学 Minimally invasive intravascular treatment device
US20140052104A1 (en) * 2011-07-25 2014-02-20 Terumo Kabushiki Kaisha Treatment device
CN104382677A (en) * 2014-11-10 2015-03-04 哈尔滨医科大学 Separable bracket pushing system
CN204995980U (en) * 2015-07-16 2016-01-27 浙江巴泰医疗科技有限公司 Drug balloon catheter
CN105307716A (en) * 2013-05-03 2016-02-03 C·R·巴德公司 Peelable protective sheath
CN105338928A (en) * 2013-06-21 2016-02-17 艾博特心血管系统公司 Protective sheath assembly for a polymer scaffold
US9387101B2 (en) * 2007-10-17 2016-07-12 C.R. Bard, Inc. Delivery system for a self-expanding device for placement in a bodily lumen

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196024A (en) * 1990-07-03 1993-03-23 Cedars-Sinai Medical Center Balloon catheter with cutting edge
CN101420913A (en) * 2006-02-24 2009-04-29 高尔韦爱尔兰国立大学 Minimally invasive intravascular treatment device
US9387101B2 (en) * 2007-10-17 2016-07-12 C.R. Bard, Inc. Delivery system for a self-expanding device for placement in a bodily lumen
US20140052104A1 (en) * 2011-07-25 2014-02-20 Terumo Kabushiki Kaisha Treatment device
CN105307716A (en) * 2013-05-03 2016-02-03 C·R·巴德公司 Peelable protective sheath
CN105338928A (en) * 2013-06-21 2016-02-17 艾博特心血管系统公司 Protective sheath assembly for a polymer scaffold
CN104382677A (en) * 2014-11-10 2015-03-04 哈尔滨医科大学 Separable bracket pushing system
CN204995980U (en) * 2015-07-16 2016-01-27 浙江巴泰医疗科技有限公司 Drug balloon catheter

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110623779A (en) * 2018-06-21 2019-12-31 连新龙 Intervene and use lag
CN110623779B (en) * 2018-06-21 2023-07-25 连新龙 Protective sleeve for intervention
CN109846583A (en) * 2019-03-27 2019-06-07 吴忠隐 A kind of aortic stents window controlling system
CN110681033A (en) * 2019-10-18 2020-01-14 四川海汇药业有限公司 Balloon protective sleeve and mounting method thereof

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Effective date of registration: 20210805

Address after: 215128 plant 3, Shicheng science and Technology Park, 1566 Yinzhong South Road, Wuzhong Economic Development Zone, Suzhou City, Jiangsu Province

Patentee after: Sano Shenchang Medical Technology Co.,Ltd.

Address before: 201613 3rd floor, building 11, 68 Zhongchuang Road, Songjiang District, Shanghai

Patentee before: ENMAI (SHANGHAI) MEDICAL TECHNOLOGY Co.,Ltd.