CN106540062A - A kind of external washout with traditional Chinese herbs agent and preparation method thereof - Google Patents

A kind of external washout with traditional Chinese herbs agent and preparation method thereof Download PDF

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Publication number
CN106540062A
CN106540062A CN201611037289.XA CN201611037289A CN106540062A CN 106540062 A CN106540062 A CN 106540062A CN 201611037289 A CN201611037289 A CN 201611037289A CN 106540062 A CN106540062 A CN 106540062A
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parts
traditional chinese
chinese herbs
external washout
herbs agent
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朱柳林
张华芬
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Xuanwei City Hao Yang Agro-Ecology Science And Technology Development Co Ltd
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Xuanwei City Hao Yang Agro-Ecology Science And Technology Development Co Ltd
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/43Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The invention discloses a kind of external washout with traditional Chinese herbs agent and preparation method thereof, the infantile eczema traditional Chinese medical science is referred to as infantile eczema, is called infantile eczema;Primary disease it is many because natural disposition intolerant to, bear a pretty, delicate skin, transporting and transforming function of the spleen and stomach dereliction of duty inside has tire fire damp and hot, is invaded by rheumatic fever heresy outward, and the two accumulates to hinder and causes in skin, and the external washout with traditional Chinese herbs agent according to the component of weight portion is:15 25 parts of Flos Lonicerae, 10 20 parts of Cortex Cinnamomi, 8 14 parts of Pericarpium Citri tangerinae, 7 13 parts of Semen Cuscutae, 10 15 parts of Spica Prunellae, 10 20 parts of Bulbus Fritillariae Thunbergii, 79 parts of Radix Arnebiae (Radix Lithospermi), 31 35 parts of Herba Abri, 10 18 parts of Lignum Sappan, 48 parts of Fructus Canarii, 24 parts of Semen Strychni.External washout with traditional Chinese herbs agent prepared by the present invention, no side effectses are easily absorbed by the body, process is simple, easy to make, and according to clinical verification, total effective rate is up to 100%.

Description

A kind of external washout with traditional Chinese herbs agent and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, specifically a kind of external washout with traditional Chinese herbs agent and preparation method thereof.
Background technology
Eczema is the common inflammatory skin diseases of infant, often shows skin rubefaction, if not when incipient Treated, infant eczema will spread intensive appearance quickly, cause to occur herpess sepage, erosion, the dry and hard yellow crusts of liquid and show As prurituss unbearably, affect larger to the healthy and daily life of infant, there is no specificity therapeutic method at present.It is clinical Antihistaminic and corticosteroid hormone etc. are adopted treatment doctor trained in Western medicine more, though controllable symptom, easily recurs.Adopting Chinese traditional treatment more Dialectical therapy for oral administration, dialectical and prescription are more complicated, and children's oral drugs are difficult, not easy to operate and popularization.
For this purpose, inventor is in clinical practice for many years, infantile eczema is treated using external washout with traditional Chinese herbs, not only achieve compared with Good curative effect, and processing ease, are adapted to medication in children feature, Small side effects.
The content of the invention
It is an object of the invention to provide a kind of external washout with traditional Chinese herbs agent and preparation method thereof, reaches human body effect good absorbing, nothing Toxic and side effects.
For achieving the above object, the present invention provides following technical scheme:
A kind of external washout with traditional Chinese herbs agent, the Chinese medicine are made up of following raw material, in parts by weight for:Flos Lonicerae 15-25 parts, meat Osmanthus 10-20 parts, Pericarpium Citri tangerinae 8-14 parts, Semen Cuscutae 7-13 parts, Spica Prunellae 10-15 parts, Bulbus Fritillariae Thunbergii 10-20 parts, Radix Arnebiae (Radix Lithospermi) 7-9 parts, Os Gallus domesticus Careless 31-35 parts, Lignum Sappan 10-18 parts, Fructus Canarii 4-8 parts, Semen Strychni 2-4 parts.
As further scheme of the invention:Component according to weight portion is:Flos Lonicerae 18-22 parts, Cortex Cinnamomi 12-18 parts, Pericarpium Citri tangerinae 10-14 parts, Semen Cuscutae 9-11 parts, Spica Prunellae 12-14 parts, Bulbus Fritillariae Thunbergii 14-18 parts, Radix Arnebiae (Radix Lithospermi) 7-9 parts, Herba Abri 31-35 parts, Lignum Sappan 12-18 parts, Fructus Canarii 4-8 parts, Semen Strychni 2-4 parts.
As further scheme of the invention:Component according to weight portion is:20 parts of Flos Lonicerae, 15 parts of Cortex Cinnamomi, Pericarpium Citri tangerinae 12 Part, 10 parts of Semen Cuscutae, 13 parts of Spica Prunellae, 16 parts of Bulbus Fritillariae Thunbergii, 8 parts of Radix Arnebiae (Radix Lithospermi), 34 parts of Herba Abri, 15 parts of Lignum Sappan, 6 parts of Fructus Canarii, Semen Strychni 3 parts of son.
A kind of preparation method of external washout with traditional Chinese herbs agent, is made as follows:
First, Flos Lonicerae, Cortex Cinnamomi, Pericarpium Citri tangerinae, Semen Cuscutae, Spica Prunellae, Bulbus Fritillariae Thunbergii, Radix Arnebiae (Radix Lithospermi), chicken are weighed according to the weight portion GUCAO, Lignum Sappan, Fructus Canarii, Semen Strychni, subsequently carry out micronizing, cross 2000-3000 mesh sieves, be then used by ethanol after micronizing Immersion 1-2h, soaking temperature is 20-30 DEG C, and distillation extraction is carried out after immersion, in triplicate, merges distillate, aseptic after filtration Fill is obtained final product.
As further scheme of the invention:In step, soaking temperature is 25 DEG C.
Compared with prior art, the invention has the beneficial effects as follows:
External washout with traditional Chinese herbs agent prepared by the present invention, no side effectses are easily absorbed by the body, process is simple, easy to make, Jing Clinical verification, total effective rate is up to 100%.
Specific embodiment
The technical scheme of this patent is described in more detail with reference to specific embodiment.
Embodiment 1
A kind of external washout with traditional Chinese herbs agent, the Chinese medicine are made up of following raw material, in parts by weight for:15 parts of Flos Lonicerae, Cortex Cinnamomi 10 parts, 8 parts of Pericarpium Citri tangerinae, 7 parts of Semen Cuscutae, 10 parts of Spica Prunellae, 10 parts of Bulbus Fritillariae Thunbergii, 7 parts of Radix Arnebiae (Radix Lithospermi), 31 parts of Herba Abri, 10 parts of Lignum Sappan, Fructus Canarii 4 parts, 2 parts of Semen Strychni.
A kind of preparation method of external washout with traditional Chinese herbs agent, is made as follows:
First, Flos Lonicerae, Cortex Cinnamomi, Pericarpium Citri tangerinae, Semen Cuscutae, Spica Prunellae, Bulbus Fritillariae Thunbergii, Radix Arnebiae (Radix Lithospermi), chicken are weighed according to the weight portion GUCAO, Lignum Sappan, Fructus Canarii, Semen Strychni, subsequently carry out micronizing, and 2000 mesh sieves are crossed after micronizing, are then used by ethanol immersion 1h, soaking temperature are 20 DEG C, and distillation extraction is carried out after immersion, in triplicate, merge distillate, and after filtration, sterile filling is obtained final product.
Embodiment 2
A kind of external washout with traditional Chinese herbs agent, the Chinese medicine are made up of following raw material, in parts by weight for:18 parts of Flos Lonicerae, Cortex Cinnamomi 12 parts, it is 10 parts of Pericarpium Citri tangerinae, 9 parts of Semen Cuscutae, 12 parts of Spica Prunellae, 14 parts of Bulbus Fritillariae Thunbergii, 7 parts of Radix Arnebiae (Radix Lithospermi), 31 parts of Herba Abri, 12 parts of Lignum Sappan, blue or green Really 4 parts, 2 parts of Semen Strychni.
A kind of preparation method of external washout with traditional Chinese herbs agent, is made as follows:
First, Flos Lonicerae, Cortex Cinnamomi, Pericarpium Citri tangerinae, Semen Cuscutae, Spica Prunellae, Bulbus Fritillariae Thunbergii, Radix Arnebiae (Radix Lithospermi), chicken are weighed according to the weight portion GUCAO, Lignum Sappan, Fructus Canarii, Semen Strychni, subsequently carry out micronizing, and 2000 mesh sieves are crossed after micronizing, are then used by ethanol immersion 1h, soaking temperature are 20 DEG C, and distillation extraction is carried out after immersion, in triplicate, merge distillate, and after filtration, sterile filling is obtained final product.
Embodiment 3
A kind of external washout with traditional Chinese herbs agent, the Chinese medicine are made up of following raw material, in parts by weight for:20 parts of Flos Lonicerae, Cortex Cinnamomi 15 parts, it is 12 parts of Pericarpium Citri tangerinae, 10 parts of Semen Cuscutae, 13 parts of Spica Prunellae, 16 parts of Bulbus Fritillariae Thunbergii, 8 parts of Radix Arnebiae (Radix Lithospermi), 34 parts of Herba Abri, 15 parts of Lignum Sappan, blue or green Really 6 parts, 3 parts of Semen Strychni.
A kind of preparation method of external washout with traditional Chinese herbs agent, is made as follows:
First, Flos Lonicerae, Cortex Cinnamomi, Pericarpium Citri tangerinae, Semen Cuscutae, Spica Prunellae, Bulbus Fritillariae Thunbergii, Radix Arnebiae (Radix Lithospermi), chicken are weighed according to the weight portion GUCAO, Lignum Sappan, Fructus Canarii, Semen Strychni, subsequently carry out micronizing, and 3000 mesh sieves are crossed after micronizing, are then used by ethanol immersion 2h, soaking temperature are 25 DEG C, and distillation extraction is carried out after immersion, in triplicate, merge distillate, and after filtration, sterile filling is obtained final product.
Embodiment 4
A kind of external washout with traditional Chinese herbs agent, the Chinese medicine are made up of following raw material, in parts by weight for:22 parts of Flos Lonicerae, Cortex Cinnamomi 18 parts, it is 14 parts of Pericarpium Citri tangerinae, 11 parts of Semen Cuscutae, 14 parts of Spica Prunellae, 18 parts of Bulbus Fritillariae Thunbergii, 9 parts of Radix Arnebiae (Radix Lithospermi), 35 parts of Herba Abri, 18 parts of Lignum Sappan, blue or green Really 8 parts, 4 parts of Semen Strychni.
A kind of preparation method of external washout with traditional Chinese herbs agent, is made as follows:
First, Flos Lonicerae, Cortex Cinnamomi, Pericarpium Citri tangerinae, Semen Cuscutae, Spica Prunellae, Bulbus Fritillariae Thunbergii, Radix Arnebiae (Radix Lithospermi), chicken are weighed according to the weight portion GUCAO, Lignum Sappan, Fructus Canarii, Semen Strychni, subsequently carry out micronizing, and 3000 mesh sieves are crossed after micronizing, are then used by ethanol immersion 2h, soaking temperature are 30 DEG C, and distillation extraction is carried out after immersion, in triplicate, merge distillate, and after filtration, sterile filling is obtained final product.
Embodiment 5
A kind of external washout with traditional Chinese herbs agent, the Chinese medicine are made up of following raw material, in parts by weight for:25 parts of Flos Lonicerae, Cortex Cinnamomi 20 parts, it is 14 parts of Pericarpium Citri tangerinae, 13 parts of Semen Cuscutae, 15 parts of Spica Prunellae, 20 parts of Bulbus Fritillariae Thunbergii, 9 parts of Radix Arnebiae (Radix Lithospermi), 35 parts of Herba Abri, 18 parts of Lignum Sappan, blue or green Really 8 parts, 4 parts of Semen Strychni.
A kind of preparation method of external washout with traditional Chinese herbs agent, is made as follows:
First, Flos Lonicerae, Cortex Cinnamomi, Pericarpium Citri tangerinae, Semen Cuscutae, Spica Prunellae, Bulbus Fritillariae Thunbergii, Radix Arnebiae (Radix Lithospermi), chicken are weighed according to the weight portion GUCAO, Lignum Sappan, Fructus Canarii, Semen Strychni, subsequently carry out micronizing, and 3000 mesh sieves are crossed after micronizing, are then used by ethanol immersion 2h, soaking temperature are 30 DEG C, and distillation extraction is carried out after immersion, in triplicate, merge distillate, and after filtration, sterile filling is obtained final product.
Clinical data
1st, physical data case chooses 200 that in July, 2015 to the Jinan, Shandong Province of in July, 2016 area hospital outpatient is accepted for medical treatment Eczema infant meets infant eczema diagnostic criteria as object of study, 0.5 to 3 year old age, all infants, by selected infant It is randomly divided into treatment group 100 and matched group 100.Two groups not statistically significant in sex, age, course of disease difference.
2nd, affected part is cleaned using external washout with traditional Chinese herbs agent prepared by the embodiment of the present invention 3 by Therapeutic Method treatment group, daily 1 dose, wipes Affected part is washed, 2 times a day.Matched group adopts triamcinolone acetonide econazole cream (Xian-Janssen Pharmaceutical Ltd.) affected part of exterior coating, often Day 2 times, two groups with 7d as 1 course for the treatment of.
3rd, curative effect determinate standard is formulated according to the Chinese State Administration of Traditional Chinese Medicines《Chinese medical disease Standardization of diagnosis and curative effect》Middle correlation Standard gives efficacy evaluation.(1) fully recover:Clinical symptoms all disappear, and skin lesion disappears completely.(2) it is effective:Clinical symptom remission is bright It is aobvious, skin lesion regression >=70%.(3) effectively:Clinical symptoms part is alleviated, skin lesion regression >=30%.(4) it is invalid:Clinical symptoms are not Change, skin lesion regression < 30%.
4th, in therapeutic outcome treatment group 100, fully recover 91, effective 7, effective 2, invalid 0, total effective rate is 100%;Fully recover 42 in 100 patients of matched group, effective 15, effective 23, invalid 20, total effective rate is 80%.Two Group difference is statistically significant, and the therapeutic effect for the treatment of group is significantly better than matched group.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of spirit or essential attributes without departing substantially from the present invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling Change is included in the present invention.
Moreover, it will be appreciated that although this specification is been described by according to embodiment, not each embodiment is only wrapped Containing an independent technical scheme, this narrating mode of description is only that those skilled in the art should for clarity Using description as an entirety, the technical scheme in each embodiment can also Jing it is appropriately combined, form those skilled in the art Understandable other embodiment.

Claims (5)

1. a kind of external washout with traditional Chinese herbs agent, it is characterised in that the Chinese medicine is made up of following raw material, in parts by weight for:Flos Lonicerae 15-25 parts, Cortex Cinnamomi 10-20 parts, Pericarpium Citri tangerinae 8-14 parts, Semen Cuscutae 7-13 parts, Spica Prunellae 10-15 parts, Bulbus Fritillariae Thunbergii 10-20 parts, Radix Arnebiae (Radix Lithospermi) 7-9 parts, Herba Abri 31-35 parts, Lignum Sappan 10-18 parts, Fructus Canarii 4-8 parts, Semen Strychni 2-4 parts.
2. external washout with traditional Chinese herbs agent according to claim 1, it is characterised in that the component according to weight portion is:Flos Lonicerae 18-22 Part, Cortex Cinnamomi 12-18 parts, Pericarpium Citri tangerinae 10-14 parts, Semen Cuscutae 9-11 parts, Spica Prunellae 12-14 parts, Bulbus Fritillariae Thunbergii 14-18 parts, Radix Arnebiae (Radix Lithospermi) 7-9 Part, Herba Abri 31-35 parts, Lignum Sappan 12-18 parts, Fructus Canarii 4-8 parts, Semen Strychni 2-4 parts.
3. external washout with traditional Chinese herbs agent according to claim 1 and 2, it is characterised in that the component according to weight portion is:Flos Lonicerae 20 Part, 15 parts of Cortex Cinnamomi, 12 parts of Pericarpium Citri tangerinae, 10 parts of Semen Cuscutae, 13 parts of Spica Prunellae, 16 parts of Bulbus Fritillariae Thunbergii, 8 parts of Radix Arnebiae (Radix Lithospermi), 34 parts of Herba Abri, Lignum Sappan 15 parts, 6 parts of Fructus Canarii, 3 parts of Semen Strychni.
4. a kind of preparation method of the external washout with traditional Chinese herbs agent as described in claim 1-3 is arbitrary, it is characterised in that as follows It is made:
First, according to the weight portion weigh Flos Lonicerae, Cortex Cinnamomi, Pericarpium Citri tangerinae, Semen Cuscutae, Spica Prunellae, Bulbus Fritillariae Thunbergii, Radix Arnebiae (Radix Lithospermi), Herba Abri, Lignum Sappan, Fructus Canarii, Semen Strychni, subsequently carry out micronizing, and 2000-3000 mesh sieves are crossed after micronizing, are then used by ethanol immersion 1-2h, soaking temperature are 20-30 DEG C, and distillation extraction is carried out after immersion, in triplicate, merge distillate, sterile filling after filtration Obtain final product.
5. the preparation method of external washout with traditional Chinese herbs agent according to claim 4, it is characterised in that soaking temperature is 25 in step ℃。
CN201611037289.XA 2016-11-23 2016-11-23 A kind of external washout with traditional Chinese herbs agent and preparation method thereof Pending CN106540062A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142716A (en) * 2013-03-07 2013-06-12 邱忠亮 Chinese medicine external lotion for treating infantile eczema
CN105250760A (en) * 2015-10-15 2016-01-20 高艳丽 Traditional Chinese medicine external lotion for treating infant eczema
CN105902699A (en) * 2016-05-07 2016-08-31 刘茂花 Traditional Chinese medicine external lotion for treating infantile eczema

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142716A (en) * 2013-03-07 2013-06-12 邱忠亮 Chinese medicine external lotion for treating infantile eczema
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