CN106539820A - A kind of marine organisms ionic liquid - Google Patents

A kind of marine organisms ionic liquid Download PDF

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Publication number
CN106539820A
CN106539820A CN201611058248.9A CN201611058248A CN106539820A CN 106539820 A CN106539820 A CN 106539820A CN 201611058248 A CN201611058248 A CN 201611058248A CN 106539820 A CN106539820 A CN 106539820A
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China
Prior art keywords
ionic liquid
marine organisms
sodium
algal polysaccharides
marine
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Pending
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CN201611058248.9A
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Chinese (zh)
Inventor
迟桂丽
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Weihai Blue Ocean Biotechnology Co Ltd
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Weihai Blue Ocean Biotechnology Co Ltd
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Priority to CN201611058248.9A priority Critical patent/CN106539820A/en
Publication of CN106539820A publication Critical patent/CN106539820A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/22Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/32Manganese; Compounds thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a kind of marine organisms ionic liquid, belongs to technical field of bioengineering.The present invention includes algal polysaccharides extract, sodium carbonate, potassium chloride, sodium metasilicate, borax, zinc sulfate, manganese sulfate, medical stone, alum, sodium selenite, white sugar and water.Marine organisms ionic liquid disclosed by the invention can adjust human nutrition balance, enhance immunity, promote the endocrine of " enzyme " needed by human, increase the negative electricity potential difference inside and outside human body cell, make the oxygen-enriched ion nutrient solution of the more effective organism-absorbing of cell, exclude intracellular toxin, oxygen-enriched environment is provided for internal cell, auxiliary improves faintly acid physique, suppresses the internal storage of toxin and pathogenic factor, clears up internal system, pore refining, detoxicating, relieving inflammation, activation face and cortex cell, keep life power, promote longevity.

Description

A kind of marine organisms ionic liquid
Technical field
The present invention relates to technical field of bioengineering, more particularly to a kind of marine organisms ionic liquid.
Background technology
Edible marine alga is one of halobiontic valuable source, and which is not only a healthy pollution-free food source of the mankind, And be the life killers such as mankind's prevention " three high diseases ", cardiovascular and cerebrovascular disease and cancer infringement, pursue long-lived alkaline health care food Product, common marine alga have sea-tangle, sea sedge dish, undaria pinnitafida, asparagus, sargassum, spirulina etc.
International nutritionist's prediction marine alga will become the healthy food of 21 century.The current domestic important nutritive value to marine alga is still Understanding is inadequate, also only resides within cool Hot dishes on dry seaweed product and dining table etc. first (thick) is processed, the low level stage.Make sea Algae is abundant and the alimentary health-care function of uniqueness and huge economic worth fail to be dug well and lifted.
Marine alga belongs to low cryptogam, and in sea-plant, shared quantity and kind are at most most extensively main point For-blue-green algae, green alga, four big class of red algae and brown alga, the microalgaes such as diatom, dinoflagellate, chrysophyceae are additionally included.Containing abundant in marine alga Polysaccharide, account for more than the 50% of marine alga dry weight.
Algal polysaccharides are important component parts in marine alga, belong to the one kind in plant polyose, are a kind of natural active matters, The HMW carbohydrate being connected to form by glycosidic bond by multiple identical or different monosaccharide groups, is between alginic cell With the general name of intracellular contained various polymeric carbohydrates.
The algal polysaccharides of separate sources, the Monomer containing sugar moiety for constituting polysaccharide are also differed.It is a kind of multi-component mixture.By The nonreducing sugar being made up of special disaccharide molecule in trehalose, property is highly stable, can high temperature, it is high and cold, be dried and lose Special diaphragm is formed in cell surface under conditions of water etc. is severe, biomolecular structure is effectively protected and is not destroyed, from And the life process and biological characteristic of the body that sustains life.Therefore trehalose has the good reputation of the sugar of life.
In recent years, trehalose is had a sudden rise in social status, as NMF, the stabilizer of bioactivator and protective agent, can be extensive For industry-by-industries such as biologic product, medicine, food, cosmetics and agricultural sciences.
Ionic liquid (or claiming ionic liquid) refers to the liquid being composed entirely of ions, the such as KCI under high temperature, and KOH is in Liquid condition, now they are exactly ionic liquid.The material being made up of ion being in a liquid state at a temperature of room temperature or near room temperature, Referred to as (ionic liquid at room temperature is often accompanied by the presence of hydrogen bond, is defined as room temperature molten salt a little for ionic liquid at room temperature, room temperature molten salt Reluctantly), organic ion liquid etc., there is no unified title at present, but tends to abbreviation ionic liquid.
The exploitation of ionic liquid in recent years develops a kind of ionic liquid meaning for strengthening body immunity with using more and more Justice is great.
The content of the invention
It is not enough in order to make up the above, the invention provides one kind can effectively adjust human nutrition balance, enhance immunity Marine organisms ionic liquid.
The technical scheme is that:
A kind of marine organisms ionic liquid, including algal polysaccharides extract, sodium carbonate, potassium chloride, sodium metasilicate, borax, zinc sulfate, sulphur Sour manganese, medical stone, alum, sodium selenite, white sugar and water.
Preferably, algal polysaccharides extract of the algal polysaccharides extract for opotism, sargassum or spirulina.
Preferably, in the algal polysaccharides extract, the mass fraction of algal polysaccharides is 70-90%.
Further, in parts by weight, including 1-35 part algal polysaccharides extracts, 1-25 part sodium carbonate, 1-15 parts Potassium chloride, 1-14 part sodium metasilicate, 1-23 part boraxs, 1-12 part zinc sulfate, 0.5-10 part manganese sulfates, 5-20 part medical stones, 0.5- 12 parts of alum, 0.01-10 part sodium selenites, 1-25 parts white sugar and 80-200 part water.
Further, in parts by weight, including 10-20 part algal polysaccharides extracts, 6-17 part sodium carbonate, 3-12 parts Potassium chloride, 3-12 part sodium metasilicate, 6-16 part boraxs, 3-9 part zinc sulfate, 2-7 part manganese sulfates, 8-15 part medical stones, 3-8 parts are bright Alum, 0.5-3 part sodium selenites, 5-20 parts white sugar and 100-180 part water.
Preferably, in the medical stone, the content of strontium carbonate is 0.00001%-0.00005%, Germania content For 0.0001-0.0003%.
The preparation method of the marine organisms ionic liquid, including step:
1) by sodium carbonate, potassium chloride, sodium metasilicate, borax, zinc sulfate, manganese sulfate, medical stone, alum, sodium selenite, white sugar and water Mixing, and 90-120 DEG C is heated to, stir, obtain mixed liquor;
2) above-mentioned mixed liquor stands, and is subsequently cooled to room temperature, filters solid slag, obtains mixing clear liquid;
3) the mixing stillness of night is well mixed with algal polysaccharides extract, it is canned after oxygen oxygen dissolver dissolved oxygen processed.
Preferably, step 2) time of repose be 20-40 hours.
Preferably, medical stone powder is broken to 10-200 mesh.By links such as Crushing of Ultrafine, heatings, in making medical stone Trace element strontium, germanium, are cemented out by potassium, sodium.
Wherein, algal polysaccharides extract:
It is purchased from Shaanxi Bo Lin Bioisystech Co., Ltd, product specification:Algal polysaccharides 80%, take off turquois fine powder. Pharmacologically active:There is to cell immunoregulation effect, antitumor action, antimutagenic effect, Cell differentiation inducing activity, antiviral, resist The multiple efficacies such as oxidation;Endemicgoiter can be prevented and treated, cholesterol is significantly reduced;Increase the absorption of calcium;To hypertension, artery Hardening and liposis have certain prevention and auxiliary therapeutic action;Clinical research has antifatigue effect, lipidemia, blood coagulation Effect and its application in cardiovascular and cerebrovascular disease and hypoglycemic activity and radioactive protection effect etc..
The using method of marine organisms ionic liquid of the present invention:
1st, the marine organisms ionic liquid to being biological ionic liquid and water with 1 with method:200 ratio face or cortex local Spray.
2nd, the marine organisms ionic liquid to being for oral administration with method, take above-mentioned marine organisms ionic liquid and water with 1:2000 Dilution proportion after take orally.
Beneficial effects of the present invention are:
The adjustable human nutrition balance of the marine organisms ionic liquid of the present invention, enhance immunity promote the interior of " enzyme " needed by human Secretion, increases the negative electricity potential difference inside and outside human body cell, makes the oxygen-enriched ion nutrient solution of the more effective organism-absorbing of human body cell, excludes Intracellular toxin, provides oxygen-enriched environment for internal cell, and auxiliary improves faintly acid physique, suppresses toxin internal with pathogenic factor Storage, clears up internal system, pore refining, detoxicating, relieving inflammation, activation face and cortex cell, keeps life power, macrobiosis benefit Longevity.Clinical testing proves that take the people of the marine organisms ionic liquid of the present invention, resistance against diseases is substantially better than does not take sea of the invention The people of foreign biological ion liquid, the crowd's hematologic disease after taking are reduced with the incidence of disease of virosis.The present invention marine organisms from Sub- liquid, has functions that fabulous strengthen immunity, is suitable to promote.
Specific embodiment
In following examples, algal polysaccharides extract is purchased for Shaanxi Bo Lin Bioisystech Co., Ltd, algal polysaccharides Mass fraction is the algal polysaccharides extract of 80% sea-tangle or sargassum or spirulina.
Embodiment 1
A kind of marine organisms ionic liquid, including 15g algal polysaccharides extracts, 12g sodium carbonate, 8g potassium chloride, 7g sodium metasilicate, 11g (in medical stone, the content of strontium carbonate is that 0.00003%, Germania content is for borax, 6g zinc sulfate, 4g manganese sulfates, 12g medical stones 0.0002%), 5g alum, 1g sodium selenites, 12g white sugar and 140g water.
The preparation method of marine organisms ionic liquid, including step:
1) by sodium carbonate, potassium chloride, sodium metasilicate, borax, zinc sulfate, manganese sulfate, medical stone (being crushed to 50 mesh), alum, sub- selenium The mixing of sour sodium, white sugar and water, and 100 DEG C are heated to, stir, obtain mixed liquor;
2) above-mentioned mixed liquor insulation stands 24 hours, is subsequently cooled to room temperature, filters solid slag, obtains mixing clear liquid;
3) the mixing stillness of night is well mixed with the algal polysaccharides extract of sea-tangle, it is fully molten by oxygen oxygen dissolver 30min processed It is canned after oxygen.
Embodiment 2
A kind of marine organisms ionic liquid, including 20g algal polysaccharides extracts, 6g sodium carbonate, 12g potassium chloride, 3g sodium metasilicate, 16g (in medical stone, the content of strontium carbonate is that 0.00005%, Germania content is for borax, 3g zinc sulfate, 7g manganese sulfates, 8g medical stones 0.0001%), 8g alum, 0.5g sodium selenites, 20g white sugar and 120g water.
The preparation method of marine organisms ionic liquid, including step:
1) by sodium carbonate, potassium chloride, sodium metasilicate, borax, zinc sulfate, manganese sulfate, medical stone (being crushed to 100 mesh), alum, sub- selenium The mixing of sour sodium, white sugar and water, and 110 DEG C are heated to, stir, obtain mixed liquor;
2) above-mentioned mixed liquor insulation stands 30 hours, is subsequently cooled to room temperature, filters solid slag, obtains mixing clear liquid;
3) the mixing stillness of night is well mixed with the algal polysaccharides extract of sargassum, it is abundant by oxygen oxygen dissolver 30min processed It is canned after dissolved oxygen.
Embodiment 3
A kind of marine organisms ionic liquid, including 10g algal polysaccharides extracts, 12g sodium carbonate, 3g potassium chloride, 12g sodium metasilicate, 6g (in medical stone, the content of strontium carbonate is that 0.00002%, Germania content is for borax, 9g zinc sulfate, 2g manganese sulfates, 15g medical stones 0.0002%), 3g alum, 3g sodium selenites, 5g white sugar and 170g water.
The preparation method of marine organisms ionic liquid, including step:
1) by sodium carbonate, potassium chloride, sodium metasilicate, borax, zinc sulfate, manganese sulfate, medical stone (being crushed to 100 mesh), alum, sub- selenium The mixing of sour sodium, white sugar and water, and 90 DEG C are heated to, stir, obtain mixed liquor;
2) above-mentioned mixed liquor insulation stands 40 hours, is subsequently cooled to room temperature, filters solid slag, obtains mixing clear liquid;
3) the mixing stillness of night is well mixed with the algal polysaccharides extract of spirulina, it is abundant by oxygen oxygen dissolver 30min processed It is canned after dissolved oxygen.
Embodiment 4
A kind of marine organisms ionic liquid, including 17g algal polysaccharides extracts, 15g sodium carbonate, 4g potassium chloride, 4g sodium metasilicate, 12g (in medical stone, the content of strontium carbonate is that 0.00003%, Germania content is for borax, 4g zinc sulfate, 6g manganese sulfates, 11g medical stones 0.0003%), 7g alum, 1g sodium selenites, 8g white sugar and 150g water.
The preparation method of marine organisms ionic liquid, including step:
1) by sodium carbonate, potassium chloride, sodium metasilicate, borax, zinc sulfate, manganese sulfate, medical stone (being crushed to 80 mesh), alum, sub- selenium The mixing of sour sodium, white sugar and water, and 120 DEG C are heated to, stir, obtain mixed liquor;
2) above-mentioned mixed liquor insulation stands 20 hours, is subsequently cooled to room temperature, filters solid slag, obtains mixing clear liquid;
3) the mixing stillness of night is well mixed with the algal polysaccharides extract of sargassum, it is abundant by oxygen oxygen dissolver 30min processed It is canned after dissolved oxygen.

Claims (9)

1. a kind of marine organisms ionic liquid, it is characterised in that including algal polysaccharides extract, sodium carbonate, potassium chloride, sodium metasilicate, Borax, zinc sulfate, manganese sulfate, medical stone, alum, sodium selenite, white sugar and water.
2. marine organisms ionic liquid as claimed in claim 1, it is characterised in that:The algal polysaccharides extract is opotism, horse hair The algal polysaccharides extract of algae or spirulina.
3. marine organisms ionic liquid as claimed in claim 1 or 2, it is characterised in that:In the algal polysaccharides extract, marine alga is more The mass fraction of sugar is 70-90%.
4. marine organisms ionic liquid as claimed in claim 3, it is characterised in that:In parts by weight, including 1-35 part marine algas Polysaccharide extraction liquid, 1-25 part sodium carbonate, 1-15 part potassium chloride, 1-14 part sodium metasilicate, 1-23 part boraxs, 1-12 part zinc sulfate, 0.5-10 part manganese sulfates, 5-20 part medical stones, 0.5-12 part alum, 0.01-10 part sodium selenites, 1-25 parts white sugar and 80-200 Part water.
5. marine organisms ionic liquid as claimed in claim 4, it is characterised in that:In parts by weight, including 10-20 part marine algas Polysaccharide extraction liquid, 6-17 part sodium carbonate, 3-12 part potassium chloride, 3-12 part sodium metasilicate, 6-16 part boraxs, 3-9 part zinc sulfate, 2-7 Part manganese sulfate, 8-15 part medical stones, 3-8 part alum, 0.5-3 part sodium selenites, 5-20 parts white sugar and 100-180 part water.
6. marine organisms ionic liquid as claimed in claim 3, it is characterised in that:In the medical stone, the content of strontium carbonate is 0.00001%-0.00005%, Germania content are 0.0001-0.0003%.
7. the preparation method of marine organisms ionic liquid as claimed in claim 1, it is characterised in that including step:
1) by sodium carbonate, potassium chloride, sodium metasilicate, borax, zinc sulfate, manganese sulfate, medical stone, alum, sodium selenite, white sugar and water Mixing, and 90-120 DEG C is heated to, stir, obtain mixed liquor;
2) above-mentioned mixed liquor stands, and is subsequently cooled to room temperature, filters solid slag, obtains mixing clear liquid;
3) the mixing stillness of night is well mixed with algal polysaccharides extract, it is canned after oxygen oxygen dissolver dissolved oxygen processed.
8. the preparation method of marine organisms ionic liquid as claimed in claim 7, it is characterised in that:Step 2) time of repose be 20- 40 hours.
9. the preparation method of marine organisms ionic liquid as claimed in claim 7, it is characterised in that:Medical stone powder is broken to 10-200 Mesh.
CN201611058248.9A 2016-11-27 2016-11-27 A kind of marine organisms ionic liquid Pending CN106539820A (en)

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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110342976A (en) * 2018-04-04 2019-10-18 金仁哲 A kind of ion animals and plants nutrient solution
CN111838662A (en) * 2020-07-31 2020-10-30 广西天缘绿生物科技有限公司 High negative potential plantain fruit extract

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110342976A (en) * 2018-04-04 2019-10-18 金仁哲 A kind of ion animals and plants nutrient solution
CN111838662A (en) * 2020-07-31 2020-10-30 广西天缘绿生物科技有限公司 High negative potential plantain fruit extract

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Application publication date: 20170329