CN106539695A - A kind of toothpaste without preservative - Google Patents
A kind of toothpaste without preservative Download PDFInfo
- Publication number
- CN106539695A CN106539695A CN201610940717.3A CN201610940717A CN106539695A CN 106539695 A CN106539695 A CN 106539695A CN 201610940717 A CN201610940717 A CN 201610940717A CN 106539695 A CN106539695 A CN 106539695A
- Authority
- CN
- China
- Prior art keywords
- toothpaste
- agent
- preservative
- preservative according
- sodium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to a kind of toothpaste without preservative, in the formulation of tooth-paste, each raw materials by weight is composed of the following components：Abrasivuss 20%～60%, electrolyte 5%～50%, wetting agent 1%～30%, foaming agent 0.1%～5%, thickening agent 0.1%～5%, sweeting agent 0～3%, essence 0～3%, pigment 0～1%, other functional components 0～10%, balance of water.The present invention provides a kind of healthy toothpaste without preservative and with natural disinfection anti-inflammatory effect.
Description
Technical field
The present invention relates to a kind of toothpaste without preservative, belongs to cosmetics of everyday use technical field.
Background technology
Under conditions of high concentration electrolyte is present, the osmotic pressure of the intracellular protein solution of microorganism and antibacterial is far little
In the osmotic pressure of extracellular electrolyte, now, the intracellular hydrone of microorganism and antibacterial then can be by cell membrane from infiltration
The little side of pressure penetrates into the big side of osmotic pressure, that is, penetrates into outside cell membrane from cell membrane, so that cell dehydration
It is lethal, so as to reach antiseptical purpose.Our common Sal meat curings are exactly that the Sodium Chloride that make use of high concentration can press down
The effect of antibacterial processed.
With the improvement of people's living standards, to personal cleanliness and the requirement more and more higher of nursing, and oral cavity is used as human body
Gate, people to oral cavity cleaning and nursing safety especially pay close attention to.But all add in current almost all of formulation of tooth-paste
Preservative, the effect of preservative are to prevent growing for microorganism, the rational storage life for extending product, it is ensured that product is being used
Period will not go bad because of germ contamination.Many nutritional labelings in formulation of tooth-paste, probably belong to natural organic substance such as
Aminoacid, protein, saccharide, vitamin etc., none is not the excellent environment of antibacterial, microbial growth, so in this kind of toothpaste
In formula, the addition of preservative also must increase therewith.But why preservative can kill antibacterial, it is because that preservative can be with
There is chemical reaction in some of microorganism, bacterial cell composition, so that microorganism and bacterial cell death.Numerous experiment cards
Bright, more or less there is zest in preservative to human body, or even some also have carcinogenesis, if entering people by oral cavity
Body, its harm are bigger.
The electrolyte of high concentration is added in toothpaste, growing for microorganism and antibacterial can be effectively prevented, so as to no longer need
Preservative to be added, completely eliminates the negative effect brought by preservative.Meanwhile, during these electrolyte also can suppress oral cavity
Antibacterial grows, for auxiliary treatment periodontal salt, pharyngolaryngitis etc. have preferable effect, the light salt brine side of gargling recommended with doctor
Method has identical effect.
The content of the invention
It is an object of the present invention to provide a kind of toothpaste without preservative.
Technical scheme：In a kind of formulation of tooth-paste without preservative, by weight percentage by following components group
Into：
Abrasivuss 20%～60%,
Electrolyte 5%～50%,
Wetting agent 1%～30%,
Foaming agent 0.1%～5%,
Thickening agent 0.1%～5%,
Sweeting agent 0～3%,
Essence 0～3%,
Pigment 0～1%,
Other functional components 0～10%,
Balance of water.
Abrasivuss of the present invention are by Calcium Carbonate, calcium phosphate dibasic dihydrate, calcium phosphate dibasic anhydrouses, silicon dioxide, hydration
One or more composition in silicic acid, calcium pyrophosphate, sodium aluminosilicate, aluminium hydroxide, thermoplastic resin.
Electrolyte of the present invention is by Sodium Chloride, potassium chloride, sodium nitrate, potassium nitrate, sodium sulfate and potassium sulfate
Plant or various compositions.
Wetting agent of the present invention is by glycerol, Sorbitol, Polyethylene Glycol, Propylene Glycol, butanediol, pentanediol, xylose
One or more composition in alcohol, trehalose, polyglycereol and 2-pyrrolidone-5-carboxylic acid.
Foaming agent of the present invention is made up of surfactant.
Thickening agent of the present invention includes cellulose thickener, acrylic acid and methacrylic acid derivative class, starch
Class, melon glue and its derivant, vegetalitas colloid class, one or more of Polyethylene oxide apoplexy due to endogenous wind.
Sweeting agent of the present invention is made up of one or more in saccharin sodium, sweetener, acesulfame potassium, xylitol.
Other functional components of the present invention include fluoride, plant extract, polyphosphate, menthol, dimension
Raw element, desensitizer, teeth whitening, oral odor, constitute for one or more in sterilizing oral agent.
Beneficial effects of the present invention：Preservative be instead of with the electrolyte of high concentration, it is therefore prevented that using with the addition of preservative
The negative effect to health that brought of toothpaste, have preferably simultaneously for auxiliary treatment periodontal salt, pharyngolaryngitis etc.
Effect.
Specific experiment mode
Do further detailed description, but embodiments of the present invention not limited to this in conjunction with the embodiments to the present invention.
Embodiment 1：
A kind of refrigerant toothpaste without preservative, it is composed of the following components：
Calcium Carbonate 35%,
Sodium Chloride 10%,
Glycerol 12%,
Sodium lauryl sulphate 1.5%,
Hydroxyethyl cellulose 0.3%,
Saccharin sodium 0.25%,
Essence 0.2%,
Menthol 0.3%,
Water surplus.
Embodiment 2：
A kind of whitening toothpaste without preservative, it is composed of the following components：
Calcium hydrogen phosphate 40%,
Sodium Chloride 12%,
Glycerol 12%,
Sodium lauryl sulphate 1.5%,
Hydroxyethyl cellulose 0.3%,
Saccharin sodium 0.25%,
Essence 0.3%,
Pentasodium triphosphate 5%,
Potassium nitrate 5%,
Water surplus.
Embodiment 3：
A kind of antiallergic toothpaste without preservative, it is composed of the following components：
Calcium hydrogen phosphate 40%,
Sodium Chloride 15%,
Glycerol 10%,
Sodium lauroyl sarcosine 2%,
Hydroxyethyl cellulose 0.2%,
Saccharin sodium 0.25%,
Essence 0.3%,
Potassium nitrate 5%,
Strontium chloride 2%,
Water surplus.
In order to verify the preservative efficacy of high concentration electrolyte, we adopt American Pharmacopeia USP32<51>To embodiment 1,2
Antimicrobial preservation efficacy test is carried out with 3, acquired results are as shown in table 1.
Table 1
American Pharmacopeia USP32<51>Judgment criteria be：1）Total number of bacteria is from initially to the bacterial population log reduction of 14 days
2.0 can not be less than, and from 14 days to 28 days, bacterial population can not increase；2）Mycete and yeast sum from initially by 14 days and
28 days, mycete can not increase with yeast.
According to American Pharmacopeia USP32<51>Judgment criteria, the experimental result in table 1 confirms the electrolyte of high concentration
All kinds of antibacterials can be effectively killed and be suppressed, can be used to substitute the preservative that individual is washed in shield formula.
Claims (8)
1. a kind of toothpaste without preservative, it is characterised in that composed of the following components by weight percentage：
Abrasivuss 20%～60%,
Electrolyte 5%～50%,
Wetting agent 1%～30%,
Foaming agent 0.1%～5%,
Thickening agent 0.1%～5%,
Sweeting agent 0～3%,
Essence 0～3%,
Pigment 0～1%,
Other functional components 0～10%,
Balance of water.
2. a kind of toothpaste without preservative according to claim 1, it is characterised in that the abrasivuss by Calcium Carbonate,
Calcium phosphate dibasic dihydrate, calcium phosphate dibasic anhydrouses, silicon dioxide, silicate hydrate, calcium pyrophosphate, sodium aluminosilicate, aluminium hydroxide, thermoplastic
Property resin in one or more composition.
3. a kind of toothpaste without preservative according to claim 1, it is characterised in that the electrolyte by Sodium Chloride,
One or more composition in potassium chloride, sodium nitrate, potassium nitrate, sodium sulfate and potassium sulfate.
4. a kind of toothpaste without preservative according to claim 1, it is characterised in that the wetting agent is by glycerol, mountain
In pears sugar alcohol, Polyethylene Glycol, Propylene Glycol, butanediol, pentanediol, xylitol, trehalose, polyglycereol and 2-pyrrolidone-5-carboxylic acid one
Plant or various compositions.
5. a kind of toothpaste without preservative according to claim 1, it is characterised in that the foaming agent is by surface activity
Agent is constituted.
6. a kind of toothpaste without preservative according to claim 1, it is characterised in that the thickening agent includes cellulose
Class thickening agent, acrylic acid and methacrylic acid derivative class, starch based, melon glue and its derivant, vegetalitas colloid class, polyoxy
One or more in vinyl.
7. a kind of toothpaste without preservative according to claim 1, it is characterised in that the sweeting agent by saccharin sodium,
One or more composition in sweetener, acesulfame potassium, xylitol.
8. a kind of toothpaste without preservative according to claim 1, it is characterised in that described other functional components bags
Fluoride, plant extract, polyphosphate, menthol, vitamin, desensitizer, teeth whitening, oral odor, mouth
One or more composition in the antibacterial of chamber.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610940717.3A CN106539695A (en) | 2016-10-25 | 2016-10-25 | A kind of toothpaste without preservative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610940717.3A CN106539695A (en) | 2016-10-25 | 2016-10-25 | A kind of toothpaste without preservative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106539695A true CN106539695A (en) | 2017-03-29 |
Family
ID=58393354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610940717.3A Pending CN106539695A (en) | 2016-10-25 | 2016-10-25 | A kind of toothpaste without preservative |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106539695A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108309815A (en) * | 2018-03-20 | 2018-07-24 | 绿映（上海）生物科技有限公司 | A kind of polyol blends and the preservative free toothpaste containing the polyol blends and preparation method |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1144083A (en) * | 1996-05-24 | 1997-03-05 | 李宏英 | Sodium chloride toothpaste |
| CN105792798A (en) * | 2013-12-11 | 2016-07-20 | 高露洁-棕榄公司 | High salt toothpaste with stable viscosity |
| CN105934238A (en) * | 2014-01-24 | 2016-09-07 | 高露洁-棕榄公司 | Toothpaste with alginate base rheology modifier |
| CN105992581A (en) * | 2013-12-11 | 2016-10-05 | 高露洁-棕榄公司 | Methods of treating gingivitis using high salt toothpaste |
-
2016
- 2016-10-25 CN CN201610940717.3A patent/CN106539695A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1144083A (en) * | 1996-05-24 | 1997-03-05 | 李宏英 | Sodium chloride toothpaste |
| CN105792798A (en) * | 2013-12-11 | 2016-07-20 | 高露洁-棕榄公司 | High salt toothpaste with stable viscosity |
| CN105992581A (en) * | 2013-12-11 | 2016-10-05 | 高露洁-棕榄公司 | Methods of treating gingivitis using high salt toothpaste |
| CN105934238A (en) * | 2014-01-24 | 2016-09-07 | 高露洁-棕榄公司 | Toothpaste with alginate base rheology modifier |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108309815A (en) * | 2018-03-20 | 2018-07-24 | 绿映（上海）生物科技有限公司 | A kind of polyol blends and the preservative free toothpaste containing the polyol blends and preparation method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102631304B (en) | Preparation method of shampoo salt emulsion | |
| CN106061485B (en) | Use the probiotic oral care method of carbohydrate | |
| CN104027260A (en) | Totarol-containing oral cavity nursing product | |
| CN102008399B (en) | Preparation method of antimicrobial mouthwash | |
| CN104207957A (en) | Fibroin care solution with functions of contracting genitals and whitening, and preparation method thereof | |
| CN105764479A (en) | Liquid mouthwash | |
| CN106539695A (en) | A kind of toothpaste without preservative | |
| JP2020059689A (en) | Oral composition | |
| CN106924096A (en) | A kind of ocean elite mouthwash | |
| CN106491414A (en) | A kind of collutory without preservative | |
| CN107007538A (en) | A kind of oral care composition and application containing marine element, and the toothpaste containing marine element | |
| CN111658560A (en) | Powerful private part killing lotion and preparation method thereof | |
| CN105381454B (en) | A kind of nasal cavity wetting agent containing trehalose | |
| CN106389144A (en) | Toothpaste containing antimicrobial component | |
| CN111041827A (en) | Antibacterial skin-friendly wet tissue | |
| CN111265440A (en) | Rosemary antibacterial and disinfectant wash-free hand sanitizer formula | |
| CN114983858B (en) | Ferment toothpaste and preparation method thereof | |
| CN105250181A (en) | Preparation method of cosmetic additive containing modified silk protein | |
| US20090185986A1 (en) | Application of natural mineral water with special qualities in prophylaxis, hygiene and treatment of teeth and paradontium | |
| RU2663591C2 (en) | Bleaching compositions for mouth cavity | |
| CN112587421A (en) | Washing-free hand disinfection gel containing plant extracts and preparation method and application thereof | |
| CN106727240A (en) | A kind of washing one's face without preservative, dual-purpose formula of taking a shower | |
| CN106727241A (en) | A kind of shampoo prescription containing ooze dissolved matter | |
| CN109077946A (en) | The purposes of astaxanthin | |
| KR100861806B1 (en) | Toothpaste |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wu Huabing Inventor after: Liang Yao Inventor after: Zhan Kai Inventor after: Zhao Yingxiang Inventor after: Yu Qi Inventor before: Dai Ying |
|
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180212 Address after: 410000 Changsha City, Hunan province high tech Development Zone, Yuelu Avenue West, No. 588, Changsha core city science and Technology Park, building 6, building 6 Applicant after: China Polytron Technologies Inc Address before: 410000 Hunan, Yuelu District orange Chau Street Xiaoxiang Road, the middle part of the University of science and Technology Park, Pegasus Village Building Applicant before: Changsha Huachen Biotechnology Co., Ltd. |
|
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180727 Address after: 410000 Xiaoxiang Road, Tianma Road, Tianma Road, Hunan, Changsha, Yuelu District, B4088 Applicant after: Changsha Huachen Biotechnology Co., Ltd. Address before: 410000 6, 6 Changsha road core technology park, 588 Yuelu Avenue West, Changsha high tech Development Zone, Hunan. Applicant before: China Polytron Technologies Inc |
|
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170329 |