CN106539089A - A kind of complex prebiotics and its application - Google Patents

A kind of complex prebiotics and its application Download PDF

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Publication number
CN106539089A
CN106539089A CN201610982930.0A CN201610982930A CN106539089A CN 106539089 A CN106539089 A CN 106539089A CN 201610982930 A CN201610982930 A CN 201610982930A CN 106539089 A CN106539089 A CN 106539089A
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China
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product
inulin
stachyose
prebioticses
complex prebiotics
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CN201610982930.0A
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易军如
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Individual
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38Other non-alcoholic beverages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/733Fructosans, e.g. inulin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A kind of complex prebiotics, the complex prebiotics are made up of 1 100 parts of 10 parts of stachyose and inulin by weight.This product take stachyose as leading, compatibility inulin, with the obvious advantage, makes the fermentation position of compositionss extend to whole large intestine, solves other prebioticses only the drawbacks of ascending colon ferments, can the big enteral of comprehensive propagation probiotic bacteria;Product function is very comprehensive, and existing flora optimizes function, can promote bacterial metabolism again, solves the deficiency that current prebioticses product is present on market;Also, after stachyose compatibility inulin, the physiological function of compositionss adjusts blood fat as reduced blood glucose and blood pressure, improves immunity of organisms, adjunct antineoplastic etc. and generates great synergistic function.This product can be used as the raw material or dispensing of beverage, bread and cheese, health food, special medicine purposes formula food and medicine.

Description

A kind of complex prebiotics and its application
Technical field
The present invention relates to prebioticses, and in particular to a kind of complex prebiotics by stachyose compatibility inulin, while also It is related to effect of the complex prebiotics in terms of blood sugar lowering and blood pressure, regulation blood fat, enhance immunity.
Background technology
Prebioticses be lost in a kind of modern diet, the dietary fiber beneficial to health, be that one kind can be selected Selecting property is fermented and changes constituting and active composition of food to host health profitable strain in gastrointestinal tract.Prebioticses must are fulfilled for Three conditions:1st, acidproof and hydrolytic enzyme, is not digested and assimilated with small intestinal by stomach;2nd, can be fermented by intestinal microbial population;3rd, can be optionally The growth of the intestinal beneficial bacterium such as stimulation of bifidobacteria and lactobacilluss.
It is mainly oligosaccharide substance using more prebioticses at present, such as oligomeric galactose, inulin, oligofructose, low Xylan, oligomeric isomaltose, soybean oligo saccharide, shitosan etc..The prebioticses product of those prebioticses compositions is mainly with following Three kinds of modes are present:1st, make an addition in baby milk powder as additive;2nd, with little or minimum dosage and probiotic bacteria compatibility into conjunction Raw unit's product;3rd, the prebioticses product of folk prescription abundance consumption.There is following defect in those prebioticses products:
1st, in symphysis unit product, prebioticses addition is too small, it is difficult to reach its minimum action consumption, it is more difficult to which playing prebioticses should The physiological function of the performance.
2nd, the product such as symphysis unit and probiotic bacteria is not suitable for life-time service.Medical research proves, human body life-time service probiotic bacteria, The ability that function of intestinal canal can be promoted progressively to lose self-reproduction probioticss, long human body intestinal canal will produce dependency, medically Referred to as " probiotic bacteria dependence syndrome ".And human body once suffers from " probiotic bacteria dependence syndrome ", throughout one's life all will be by probiotic oral product Come the health status for sustaining life.In addition, excessive use of probiotic bacteria is likely to become the new hotbed for breeding " superbug ".Due to Many lactic acid bacterias have a multiple drug resistance to antibiotic, through with the community life of pathogen, contact, it is likely that will be self-contained Drug resistance gene pass to pathogen, be allowed to obtain Drug resistance and become " superbug ", may can without medicine when causing infection Doctor.
3rd, folk prescription prebioticses product limitation is big.In due to various oligosaccharides prebioticses, various oligosaccharide have each Unique individual character, such as to the facilitation of various probiotic bacterias whether and strong and weak difference;To the rejection ability of various pernicious bacterias not Together;In identical colon ecological environment, the time length of fermentation is different;In fermentation, produced gas flow is different;Fermentation The species of the short-chain fatty acid produced during decomposition is different with amount;It is different in the Adhering capacity of big intestinal wall;In each region of big enteral Fermentation activity is not equal so that folk prescription prebioticses product limitation is big.And design and adopt the compound recipe prebioticses product can be preferably Solve the limitation of folk prescription prebioticses.
The content of the invention
The technical problem to be solved is:For above-mentioned the deficiencies in the prior art, there is provided a kind of formula is simplified, work( Energy is complete, safety is natural and has the complex prebiotics by stachyose compatibility inulin of Synergistic, while also providing the compound benefit Effect of the raw unit in terms of blood sugar lowering and blood pressure, regulation blood fat, enhance immunity.
In order to solve above-mentioned technical problem, the technical solution adopted in the present invention is:A kind of complex prebiotics, the compound benefit Raw unit is made up of 10 parts of stachyose and inulin 1-100 parts by weight.
Preferably, the complex prebiotics are made up of 10 parts of stachyose and inulin 1-50 parts by weight.
Preferably, the complex prebiotics are made up of 10 parts of stachyose and inulin 50-100 parts by weight.
The complex prebiotics of the present invention are water intaking threose and inulin, and mixing stirs, prepared.
This complex prebiotics product introduces natural oligosaccharide --- stachyose.Stachyose is naturally occurring a kind of four Sugar, belongs to oligomeric galactose, is not hydrolyzed by human digestive enzymes, can intactly enter colon, and by the zymolysis of intestinal bacteria institute, energy Bacillus bifiduss propagation is remarkably promoted, is the excellent bacillus bifiduss proliferation activity factor.Stachyose is oligomeric as rare pure natural Sugar substance. it is special with unique improvement the intestines and stomach, the liver protecting, reduction blood glucose blood pressure, regulation blood fat, auxiliary treatment chronic disease etc. Function.It is leading with stachyose in this composition product, to promoting China's oligosaccharide and prebioticses industry development or weight will be produced The strategic importance wanted.Also, another composition in compatibility is inulin, in inulin, it is more than 10 containing oligofructose and the degree of polymerization Long-chain inulin, its fermenting speed fall between, and fermentation site distribution, can comprehensive propagation large intestine in the regional of large intestine Interior probiotic bacteria.
The complex prebiotics product stachyose of the present invention is with the obvious advantage with inulin compatibility, expands the fermentation position of compositionss To whole large intestine, solve other prebioticses only the drawbacks of ascending colon ferments, can the big enteral of comprehensive propagation probiotic bacteria.Plus Stachyose there is unique improvement the intestines and stomach, the liver protecting, reduce blood glucose blood pressure, adjust the spies such as blood fat, auxiliary treatment chronic disease The good physiological function of distinguished service energy, makes product function very comprehensive, can ferment in regions such as ascending colon, descending colon;Existing bacterium Group's optimization function, can promote bacterial metabolism again, solve the deficiency that current prebioticses product is present on market.Also, stachyose After compatibility inulin, the physiological function of compositionss adjusts blood fat as reduced diabeticss fasting glucose, blood pressure, improves body and exempts from Epidemic disease power, adjunct antineoplastic etc. generate great synergistic function, make a concrete analysis of as follows:
1. the effect in terms of blood sugar lowering:
40 type 2 diabetes mellitus patients are recruited, after completing informed consent, is divided into matched group(10), inulin group(10), stachyose Group(10), stachyose+inulin group(10)Totally four groups, collective carries out a Knowledge About Diabetes Mellitus Among propaganda and education and diabetic diet Education, and measure patient's fasting glucose(FGB)Index, averages as A.Matched group only takes Frank diabetes mellitus diet, inulin Group takes Frank diabetes mellitus diet+12g inulin/day, stachyose group to take Frank diabetes mellitus diet+5g stachyose/day, this product Group takes Frank diabetes mellitus diet+10g this products(Stachyose+inulin)The intervention stratege in/day, measures patient on an empty stomach again when 8 weeks Blood glucose(FGB)Etc. index, average as B.Fasting glucose before and after calculating(FGB)Difference C, i.e. C=B-A, that is, each group is to sky The impact of abdomen blood glucose(Reduce)Ability, is shown in Fig. 1.As a result show, the patient of stachyose group, inulin group and product group of the present invention is on an empty stomach Blood glucose value decreases relative to matched group, and patient's fasting blood sugar of product group of the present invention significantly lower than stachyose group and Inulin group, shows, product of the present invention has synergistic function well to reducing patient's fasting glucose.
From the foregoing, it will be observed that product of the present invention makes product fermentation position expansion using with the obvious advantage after stachyose and inulin compatibility To whole large intestine;Simultaneously there is good coordination potentiation, powerful physiological function is brought, can reduce blood glucose and blood pressure, Adjust blood fat, enhance immunity, adjunct antineoplastic.This product can be used as beverage, bread and cheese, health food, special medicine The raw material or dispensing of way formula food and medicine is used.
Description of the drawings
Fig. 1 is product of the present invention to diabeticss fasting glucose index(FBG)Affect figure.
Specific embodiment
Embodiment 1
1 part of water intaking threose 10 and inulin, mixing, stir by weight, obtain final product the complex prebiotics product of the present invention.
Embodiment 2
30 parts of water intaking threose 10 and inulin, mixing, stir by weight, obtain final product the complex prebiotics product of the present invention.
Embodiment 3
50 parts of water intaking threose 10 and inulin, mixing, stir by weight, obtain final product the complex prebiotics product of the present invention.
Embodiment 4
70 parts of water intaking threose 10 and inulin, mixing, stir by weight, obtain final product the complex prebiotics product of the present invention.
Embodiment 5
100 parts of water intaking threose 10 and inulin, mixing, stir by weight, obtain final product the complex prebiotics product of the present invention.

Claims (5)

1. a kind of complex prebiotics, it is characterised in that the complex prebiotics are by weight by 10 parts of stachyose and inulin 1-100 parts Composition.
2. complex prebiotics as claimed in claim 1, it is characterised in that the complex prebiotics are by weight by stachyose 10 Part and inulin 1-50 parts composition.
3. complex prebiotics as claimed in claim 1, it is characterised in that the complex prebiotics are by weight by stachyose 10 Part and inulin 50-100 parts composition.
4. application of the complex prebiotics described in claim 1 or 2 or 3 in diabeticss fasting glucose is reduced.
5. application of the complex prebiotics described in claim 1 or 2 or 3 in blood fat is adjusted.
CN201610982930.0A 2016-11-09 2016-11-09 A kind of complex prebiotics and its application Pending CN106539089A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107495383A (en) * 2017-08-14 2017-12-22 北京市营养源研究所 One kind relaxes bowel complex prebiotics and preparation method and application
CN107927789A (en) * 2017-12-01 2018-04-20 刘峰 A kind of prebiotics food and preparation method thereof
CN108719752A (en) * 2017-04-24 2018-11-02 鲁南制药集团股份有限公司 A kind of functional flour rich in nutritional ingredient
CN109006931A (en) * 2017-06-09 2018-12-18 鲁南制药集团股份有限公司 A kind of health-care moon cake
CN109007586A (en) * 2017-06-09 2018-12-18 鲁南制药集团股份有限公司 A kind of health nutritious noodle
CN109380635A (en) * 2017-08-10 2019-02-26 赵同利 A kind of inulin stachyose solid beverage
CN110432500A (en) * 2019-08-07 2019-11-12 武汉英纽林生物科技有限公司 A kind of prebiotic compositions and preparation method and purposes containing inulin

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104351786A (en) * 2014-11-18 2015-02-18 厦门百泉利康生物科技有限公司 Slimming food for changing lipophilic physique and processing method thereof
CN104783168A (en) * 2015-05-05 2015-07-22 南昌康泰利保健品有限公司 Compound nutritious powder for treating diarrhea
CN104855983A (en) * 2015-04-22 2015-08-26 劲膳美生物科技股份有限公司 Non-whole nutrient formula food for coronary heart disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104351786A (en) * 2014-11-18 2015-02-18 厦门百泉利康生物科技有限公司 Slimming food for changing lipophilic physique and processing method thereof
CN104855983A (en) * 2015-04-22 2015-08-26 劲膳美生物科技股份有限公司 Non-whole nutrient formula food for coronary heart disease
CN104783168A (en) * 2015-05-05 2015-07-22 南昌康泰利保健品有限公司 Compound nutritious powder for treating diarrhea

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108719752A (en) * 2017-04-24 2018-11-02 鲁南制药集团股份有限公司 A kind of functional flour rich in nutritional ingredient
CN109006931A (en) * 2017-06-09 2018-12-18 鲁南制药集团股份有限公司 A kind of health-care moon cake
CN109007586A (en) * 2017-06-09 2018-12-18 鲁南制药集团股份有限公司 A kind of health nutritious noodle
CN109380635A (en) * 2017-08-10 2019-02-26 赵同利 A kind of inulin stachyose solid beverage
CN107495383A (en) * 2017-08-14 2017-12-22 北京市营养源研究所 One kind relaxes bowel complex prebiotics and preparation method and application
CN107927789A (en) * 2017-12-01 2018-04-20 刘峰 A kind of prebiotics food and preparation method thereof
CN110432500A (en) * 2019-08-07 2019-11-12 武汉英纽林生物科技有限公司 A kind of prebiotic compositions and preparation method and purposes containing inulin

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Application publication date: 20170329