CN106530923B - One kind being based on the adjustable simulated eye of spatial light modulator aberration and its aberration adjusting method - Google Patents

One kind being based on the adjustable simulated eye of spatial light modulator aberration and its aberration adjusting method Download PDF

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CN106530923B
CN106530923B CN201610907657.5A CN201610907657A CN106530923B CN 106530923 B CN106530923 B CN 106530923B CN 201610907657 A CN201610907657 A CN 201610907657A CN 106530923 B CN106530923 B CN 106530923B
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aberration
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emulation
eye
spatial light
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江慧绿
李超宏
廖娜
厉以宇
陈浩
王勤美
黄锦海
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Wenzhou Medical University
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Abstract

One kind being based on the adjustable simulated eye of spatial light modulator aberration and its aberration adjusting method, including emulates cornea component, emulation iris component, emulates crystalline body component, simulated retinal component, shell, transparency liquid and computer;The emulation is crystalline, and spatial light modulator can be used in body component, the change of human eye aberration is realized by changing spatial light modulator, uniqueness ingenious in design, various human eyes can be replaced in any ophthalmological instrument equipment, facilitate ophthalmology department teaching, provide reliable true human-eye model for Ophthalmologic apparatus, and has the characteristics that easy to operate, efficient, precision is high, authenticity is good, adjustable range is wide, can real-time observing eye bottom imaging.

Description

One kind being based on the adjustable simulated eye of spatial light modulator aberration and its aberration adjusting method
Technical field
The present invention relates to the adjustable simulated eye technical fields of the aberration for being related to combining adaptive optical technology, and in particular to one Kind is based on the adjustable simulated eye of spatial light modulator aberration and its aberration adjusting method.
Background technology
Many ophthalmological instruments or the ophthalmic system of research and development will use subject in ophthalmology department teaching either process of scientific research It is unstable etc. due to inevitably there is the system of student's improper use or research and development in teaching either process of scientific research as check object Factor, phenomena such as so as to cause subject's human eye injured;Meanwhile the subject of interim urgent need or cooperation for a long time is more difficult It finds, these situations all can bring inconvenience to scientific research or teaching person;In addition, everyone has different human eyes structures, It is most typical to have myopia, farsightedness etc., different human eye aberrations will be generated when observing object, to checking that it is different that equipment generates Effect, thus design a kind of human eye aberration it is adjustable can the simulated eye of real simulation human eye there is very important research significance. In addition, different human eye difference viewing angles will produce different human eye aberrations, to which eyeground will present out difference when observing object Conjugate image, realtime dynamic observation human eye is ametropia, and adjusting causes the variation of eyeground conjugate image to have human eye aberration regulative mode Certain research significance, so being highly desirable to design a kind of device of energy real time dynamic simulation human eye aberration variation.
The simulated eye occurred currently on the market is essentially all static simulation eye, and many ophthalmological instrument calibration or test are all Using static simulation eye, intraocular structure can not be simulated by change to realize that dioptric is adjustable(Human eye aberration is adjustable), can not meet Function needed for teaching or scientific research, can only simulate various ametropia situations by using the simulated eye of different diopters, Realize observation of use instrument and the test of different human eyes, disadvantage is inconvenient for operation, and efficiency is low, and authenticity is poor, and precision is low, cannot be real-time The features such as dynamic observation.In addition, also occurring having few part in the market with the adjustable simulated eye of simple dioptric, although can mould Quasi- long sight or myopia, but be all deterministic simulation, various human eye aberrations accurately can not be simulated or be designed, also can not really be reflected Go out the image formed by eyeground by human eye, precision is low, and regulating power is weak, and authenticity is poor(It is true human eye cannot to be simulated completely Aberration), the shortcomings of being unable to realtime dynamic observation.
In Chinese invention patent CN201210132443, a kind of adjustable simulated eye of diopter is described, people can only be changed The individual aberrations of eye, can not real simulation human eye, also can not really reflect that ametropia human eye is schemed by human eye formed by eyeground As situation, the visible patent CN201210132443 of particular content.Similar patent also has patent CN201610051712 etc., about base Do not saw substantially in the adjustable simulated eye of spatial light modulator aberration and its real time dynamic simulation device patent.
Therefore, there is an urgent need to a kind of dress based on the adjustable simulated eye of spatial light modulator aberration and its real time dynamic simulation It sets, according to different human eye aberrations, simulates true human eye aberration, realize observation and test, observe the eye in the case of various aberrations Bottom institute can replace various human eyes at image in any ophthalmological instrument equipment, and have it is easy to operate, efficient, Precision is high, authenticity is good, adjustable range is wide, can real-time observing eye bottom imaging the features such as.
Invention content
The purpose of the present invention is overcome it is above-mentioned in the prior art the shortcomings that, the present invention, which provides, a kind of being based on space light modulation The human eye aberration of the adjustable simulated eye of device aberration and its aberration adjusting method, the simulated eye can continuously arbitrary face type be adjusted, energy Various human eye aberrations, including higher order aberratons and low order aberration are simulated, facilitates ophthalmology department teaching, provided reliably really for Ophthalmologic apparatus Human-eye model, have it is easy to operate, efficient, precision is high, authenticity is good, adjustable range is wide, can in real time observing eye bottom at Picture the features such as.
The technical solution that the present invention uses is:One kind being based on the adjustable simulated eye of spatial light modulator aberration, including Shell and computer, the housing rear are in indent dome shape, and the front end of the shell is equipped with emulation successively from outside to inside Cornea component, emulation iris component, emulation is crystalline body component, the emulation cornea component spherical protrusion outward are described It emulates iridial part of retina and is located at emulation cornea component rear portion and against the crystalline body component of emulation, the rear portion of the crystalline body component of emulation It is additionally provided with simulated retinal component, the simulated retinal component is mounted on the rear wall of shell, and the shell is simulated Crystalline body component is separated into ante-chamber and back cavity, and the ante-chamber and back cavity are described respectively filled with immiscible transparency liquid Emulation cornea component, emulates the front that crystalline body component is installed in ante-chamber, the computer and emulation at emulation iris component Crystalline body component and simulated retinal component are respectively connected with.
The emulation is crystalline, and body component includes lens, polarizing film, transmission liquid crystal spatial modulator, the lens position In the front side or rear side of polarizing film or transmission liquid crystal spatial modulator, the polarizing film is located at transmission liquid crystal space tune Device front end processed.
The transmission liquid crystal spatial modulator is made of many small liquid crystal cells and corresponding liquid crystal cells electrode.
The emulation is crystalline, and body component further includes controller and control software, and the controller is installed on shell, The control software installation is on computers.
The emulation cornea component is the thin transparent material of negative meniscus, and the emulation cornea component is that negative meniscus is thin One kind in lens or artificial cornea.
The emulation iris component is variable light hole.
The emulation is crystalline, and body component is spatial light modulator.
The simulated retinal component is photoelectric sensor.
A kind of aberration adjusting method based on the adjustable simulated eye of spatial light modulator aberration, the adjusting method include Following steps:
(1)Crystalline body component and simulated retinal component will be emulated to link together with the computer, described is imitative Very crystalline body component is spatial light modulator;
(2)Wave front aberration relevant parameter that known human eye is calculated by wave front aberration detector artificial is appointed The given wave front aberration relevant parameter of meaning, is manually entered into the control software of computer;
(3)Control software is according to the pass between driving voltage vector V needed for wave front aberration parameter vector A and spatial light modulator It is formula, it is shown as the following formula, each unit electrode drive voltage value is calculated by wave front aberration parameter and aberration response matrix,
Wherein D is aberration response matrix, and aberration response matrix can obtain in the following way:Build one adaptive System M, the Adaptable System include Shack-Hartmann wavefront sensor M2 and simulated eye M1 and light source M3, described Beam splitting chip M8, the light source M3 and beam splitting are additionally provided between Shack-Hartmann wavefront sensor M2 and the line of simulated eye M1 The line of piece M8 and the line of Shack-Hartmann wavefront sensor M2 and simulated eye M1 are mutually perpendicular to, the light source M3 with point It is additionally provided with collimation lens M9 between beam piece M8;
The dot chart of optical system wavefront division is obtained by Shack-Hartmann wavefront sensor M2, calculates human eye aberration Slope vector on dot chart detaches in slope vector and the zeroth orders aberration such as tilts, translates, to eliminate aberration in optical system Then integral inclined or translation by the independent test to spatial light modulator cell electrode, obtains aberration correction spatial light tune The aberration response matrix of device processed;
(4)Voltage value signal will be calculated and be sent to the controller, control the unit electricity of liquid crystal spatial modulator Pole driving voltage, by changing the driving voltage value being added on liquid crystal cells electrode, so that it may the phase of point-by-point control incident light, into And realize the variation of human eyes wave-front optical aberration.
The beneficial effects of the invention are as follows:The present invention provides one kind being based on the adjustable simulated eye of spatial light modulator aberration, Including emulation cornea component, emulation iris component, emulate crystalline body component, simulated retinal component, shell, transparency liquid and meter Calculation machine;The emulation is crystalline, and spatial light modulator can be used in body component, and human eye picture is realized by changing spatial light modulator The change of difference, uniqueness ingenious in design can replace various human eyes in any ophthalmological instrument equipment, ophthalmology facilitated to teach It learns, reliable true human-eye model is provided for Ophthalmologic apparatus, and with easy to operate, efficient, precision is high, authenticity is good, adjusts Adjusting range is wide, can in real time observing eye bottom imaging the features such as.
Description of the drawings
Fig. 1 is the structure sectional view of the simulated eye specific embodiment of the present invention.
Fig. 2 is the structure sectional view of specific embodiment simulation myopia shown in FIG. 1.
Fig. 3 is the structure sectional view of specific embodiment simulation farsightedness shown in FIG. 1.
Fig. 4 is the Adaptable System Experimental equipment that aberration response matrix is calculated in simulated eye of the present invention.
Fig. 5 is the structural schematic diagram of the real time dynamic simulation human eye aberration changeable device specific embodiment of the present invention.
1- emulates cornea component in figure, and 2- emulates iris component, and 3- emulates crystalline body component, 4- simulated retinal components, 5- shells, 6- transparency liquids, 7- computers, 8- ante-chambers, 9- back cavities, 31- lens, 32- polarizing films, 33- transmission liquid crystals space Modulator, 34- controllers, 35- control softwares.
Specific implementation mode
As shown in Figure 1, a kind of being based on the adjustable simulated eye of spatial light modulator aberration, including shell(5)With computer (7), the shell(5)Rear wall is in indent dome shape, the shell(5)Front end from outside to inside successively be equipped with emulation cornea Component(1), emulation iris component(2), the crystalline body component of emulation(3), the emulation cornea component(1)It is spherical convex outward Go out, the emulation cornea component(1)For the thin transparent material of negative meniscus, the emulation cornea component(1)For negative meniscus One kind in thin lens or artificial cornea.The emulation iris component(2)To can be changed light hole.The emulation crystalline lens portion Part(3)For spatial light modulator.The change of human eye aberration, the emulation crystalline lens are realized by changing spatial light modulator Component(3)It further include controller(34)And control software(35), the controller(34)It is installed to shell(5)On, it is described Control software(35)Mounted on computer(7)On.The emulation iris component 2 is located at emulation cornea component(1)Rear portion and tight By emulating crystalline body component(3), the emulation is crystalline body component(3)Rear portion be additionally provided with simulated retinal component 4, it is described Simulated retinal component 4 is photoelectric sensor.The photoelectric sensor can be ccd sensor or cmos sensor etc..It is described Simulated retinal component 4 be mounted on shell(5)Rear wall on, the shell(5)It is simulated crystalline body component(3)It is separated into Ante-chamber(8)And back cavity(9), the ante-chamber(8)And back cavity(9)Respectively filled with immiscible transparency liquid(6), described is saturating Prescribed liquid(6)Can be oil or water etc..The emulation cornea component(1), emulation iris component(2), the crystalline body component of emulation (3)It is installed in ante-chamber(8)Front, the computer(7)With the crystalline body component of emulation(3)With simulated retinal component (4)It is respectively connected with.
The emulation is crystalline body component(3)Including lens(31), polarizing film(32), transmission liquid crystal spatial modulator (33), the lens(31)Positioned at polarizing film(32)Or transmission liquid crystal spatial modulator(33)Front side or rear side, Main purpose be give simulated eye M1 mono- initial diopter, and aberration adjust by the transmission liquid crystal spatial modulator 33 It realizes, positive negative direction adjusting is carried out on the basis of given initial diopter;The polarizing film(32)Positioned at transmission liquid crystal Spatial modulator(33)Front end, for incident natural light to be converted into polarised light, the transmission liquid crystal spatial modulator It is made of many small liquid crystal cells and corresponding liquid crystal cells electrode.Required people is inputted by the control software 35 Wavefront aberration surface equation(Zernike polynomial can be used)Relevant parameter, according to wave front aberration and liquid crystal spatial modulator Relationship between driving voltage needed for 33 calculates each unit electrode drive voltage value, and voltage value signal is sent to the control Device controls the cell electrode driving voltage of liquid crystal spatial modulator, by changing the driving voltage being added on liquid crystal cells electrode Value, so that it may the phase of point-by-point control incident light, and then realize the variation of human eyes wave-front optical aberration.
The present invention can simulate human eye under different refractive status, for example, myopia state as shown in Figure 2, as shown in Figure 3 Farsightedness state, facilitate ophthalmology department teaching and system scientific research.
In order to realize that simulated eye system aberration is adjustable, in a specific embodiment of the present invention, one kind being based on space light modulation The aberration adjusting method of the adjustable simulated eye of device aberration, the adjusting method include the following steps:
(1)Crystalline body component will be emulated(Spatial light modulator)With simulated retinal component(Photoelectric sensor)With it is described Computer links together;
(2)The wave front aberration relevant parameter that known human eye is calculated by wave front aberration detector(Such as Ze Nike System of polynomials numerical value)Or artificial any given wave front aberration relevant parameter, it is manually entered into the control mounted on computer In software;
(3)Control software is according to the pass between driving voltage vector V needed for wave front aberration parameter vector A and spatial light modulator It is formula, as shown in formula 1, each unit electrode drive voltage value is calculated by wave front aberration parameter and aberration response matrix,
(1)
Wherein D is aberration response matrix, and aberration response matrix can obtain in the following way:Build one adaptive System M, as shown in figure 4, the Adaptable System includes Shack-Hartmann wavefront sensor M2 and simulated eye M1 and light source M3 is additionally provided with beam splitting chip M8, the light source between the Shack-Hartmann wavefront sensor M2 and the line of simulated eye M1 The line of the line and Shack-Hartmann wavefront sensor M2 and simulated eye M1 of M3 and beam splitting chip M8 is mutually perpendicular to, the light Collimation lens M9 is additionally provided between source M3 and beam splitting chip M8;
The dot chart of optical system wavefront division is obtained by Shack-Hartmann wavefront sensor M2, calculates human eye aberration Slope vector on dot chart detaches in slope vector and the zeroth orders aberration such as tilts, translates, to eliminate aberration in optical system Then integral inclined or translation by the independent test to spatial light modulator cell electrode, obtains aberration correction spatial light tune The aberration response matrix of device processed;
(4)Voltage value signal will be calculated and be sent to the controller, control the unit electricity of liquid crystal spatial modulator Pole driving voltage, by changing the driving voltage value being added on liquid crystal cells electrode, so that it may the phase of point-by-point control incident light, into And realize the variation of human eyes wave-front optical aberration.
Eyeground institute caused by order to realize the variation of realtime dynamic observation human eye aberration has at image change situation in the present invention In body embodiment, as shown in figure 5, a kind of real time dynamic simulation device based on the adjustable simulated eye of spatial light modulator aberration, Including wave front detector M2 and simulated eye M1 and light source M3 and head rest and human eye M4, the front of the head rest and human eye M4 It is additionally provided with moving stage and object M5, the head rest and human eye M4 are passed with the line of moving stage and object M5 and wavefront The line of sensor M2 and simulated eye M1 are mutually perpendicular to, and the simulated eye M1 is set respectively with the front end of moving stage and object M5 There is visible band pass filter M6, the visible band pass filter M6 main purposes are to filter off other than visible light Other stray lights are detected for observing object, near infrared light for aberration using visible light, and observation and aberration detection separation have Conducive to the realization of function, the front end of the light source M3 is additionally provided with collimation lens M9, the light source M3 and Wavefront sensor M2 Between the line of simulated eye M1 and head rest and human eye M4 and the line of moving stage and object M5 and Wavefront sensor M2 It is respectively equipped between beam splitting chip M8, described two beam splitting chip M8 with the intersection of the line of simulated eye M1 and is additionally provided with near-infrared band Pass filter M7.The near-infrared bandpass filter M7 main purposes are to filter the visible light sent out by object M5 through people The visible light that eye M4 and simulated eye M1 is reflected back reduces influence of the stray light to wavefront sensing accuracy.
The wave front detector M2 can be Shack-Hartmann wave front detector.
The light source M3 is super-radiance light emitting diode or laser, and wavelength selects near infrared band.Reduce eyes pair The sensitivity of light causes lenticular adjusting, to influence observation of the human eye to object.
A kind of the step of real time dynamic simulation method of real time dynamic simulation device, specific implementation and method are as follows:
(1)Human eye M4 observes object M5, and the light that object M5 is sent out enters human eye M4 through optical filter M6 and beam splitting chip M8, Cause crystalline lens to adjust, sees object clearly to reach, meanwhile, the collimated lens M9 of light sent out by light source M3 is collimated, and is incident on Human eye M4, the light to be come by human eye M4 fundus reflexes, then entered in wave front detector M2 through beam splitting chip M8 and optical filter M7, The dot chart that optical system wavefront division is obtained by Wavefront sensor M2, is sent on computer, human eye is calculated by software Slope vector of the aberration on dot chart obtains human eye aberration parameter value so as to reconstruct wave front equation;
(2)Each unit electrode voltage value is calculated according to aberration parameter vector, voltage value signal will be calculated and be sent to The simulated eye M1 controls the cell electrode voltage of liquid crystal spatial modulator 33, makes simulated eye M1 system aberrations and people at this time Eye M4 aberrations are consistent, to accurately simulate human eye;
(3)By mobile object M5, human eye can adjust crystalline honorable type to see object M5 clearly, to change human eye picture Difference, image formed by eyeground become clear by fuzzy, and simulated eye M1 can simulate people in real time by feeding back the dynamic aberration to come Aberration, image formed by eyeground are shown on computers by photoelectric sensor 4, to realize realtime dynamic observation Eyeground institute is at image change situation caused by human eye aberration variation.
The present invention's is ingenious in design based on the adjustable simulated eye of spatial light modulator aberration and its real time dynamic simulation device Uniqueness can replace various human eyes in any ophthalmological instrument equipment, facilitate that ophthalmology department teaching, provided for Ophthalmologic apparatus can By true human-eye model, and with easy to operate, efficient, precision is high, authenticity is good, adjustable range is wide, can observe in real time The features such as eyeground imaging, is suitable for large-scale promotion application.
The above is only a preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-mentioned implementation Example, all technical solutions belonged under thinking of the present invention all belong to the scope of protection of the present invention.It should be pointed out that for the art Those of ordinary skill for, several improvements and modifications without departing from the principles of the present invention, these improvements and modifications It should be regarded as protection scope of the present invention.

Claims (8)

1. one kind being based on the adjustable simulated eye of spatial light modulator aberration, including shell (5) and computer (7), the shell (5) rear wall is in indent dome shape, which is characterized in that the front end of the shell (5) is equipped with emulation cornea portion successively from outside to inside Part (1) emulates iris component (2), emulates crystalline body component (3), the outside spherical protrusion of the emulation cornea component (1), The emulation iris component (2) is located at emulation cornea component (1) rear portion and against crystalline body component (3) is emulated, and described is imitative The rear portion of very crystalline body component (3) is additionally provided with simulated retinal component (4), and the simulated retinal component (4) is mounted on shell On the rear wall of body (5), the shell (5) is simulated crystalline body component (3) and is separated into ante-chamber (8) and back cavity (9), before described Chamber (8) and back cavity (9) are respectively filled with immiscible transparency liquid (6), the emulation cornea component (1), emulation iridial part of retina Part (2) emulates the front that crystalline body component (3) is installed in ante-chamber (8), the computer (7) and the crystalline body component of emulation (3) it is respectively connected with simulated retinal component (4), the emulation is crystalline, and body component (3) includes lens (31), polarizing film (32), transmission liquid crystal spatial modulator (33), the lens (31) are located at polarizing film (32) or transmission liquid crystal space tune The front side of device (33) processed or rear side, the polarizing film (32) are located at transmission liquid crystal spatial modulator (33) front end.
2. according to claim 1 a kind of based on the adjustable simulated eye of spatial light modulator aberration, which is characterized in that described Transmission liquid crystal spatial modulator be made of many small liquid crystal cells and corresponding liquid crystal cells electrode.
3. according to claim 1 a kind of based on the adjustable simulated eye of spatial light modulator aberration, which is characterized in that described The crystalline body component of emulation (3) further include controller (34) and control software (35), the controller (34) is installed to shell (5) on, the control software (35) is mounted on computer (7).
4. according to claim 1 a kind of based on the adjustable simulated eye of spatial light modulator aberration, which is characterized in that described Emulation cornea component (1) be the thin transparent material of negative meniscus, the emulation cornea component (1) be negative meniscus thin lens or One kind in artificial cornea.
5. according to claim 1 a kind of based on the adjustable simulated eye of spatial light modulator aberration, which is characterized in that described Emulation iris component (2) be variable light hole.
6. according to claim 1 a kind of based on the adjustable simulated eye of spatial light modulator aberration, which is characterized in that described The crystalline body component of emulation (3) be spatial light modulator.
7. according to claim 1 a kind of based on the adjustable simulated eye of spatial light modulator aberration, which is characterized in that described Simulated retinal component (4) be photoelectric sensor.
8. a kind of aberration adjusting method described in claim 1 based on the adjustable simulated eye of spatial light modulator aberration, special Sign is that the adjusting method includes the following steps:
(1) crystalline body component and simulated retinal component will be emulated to link together with the computer, the emulation is brilliant Shape body component is spatial light modulator;
(2) the wave front aberration relevant parameter that known human eye is calculated by wave front aberration detector or it is artificial arbitrarily to Fixed wave front aberration relevant parameter, is manually entered into the control software of computer;
(3) control software is according to the relationship between driving voltage vector V needed for wave front aberration parameter vector A and spatial light modulator Formula, it is shown as the following formula, each unit electrode drive voltage value is calculated by wave front aberration parameter and aberration response matrix,
A=D × V
Wherein D is aberration response matrix, and aberration response matrix can obtain in the following way:Build one Adaptable System M, the Adaptable System include Shack-Hartmann wavefront sensor M2 and simulated eye M1 and light source M3, the Shack- Beam splitting chip M8, the light source M3 and beam splitting chip M8 are additionally provided between Hartmann wave front sensor M2 and the line of simulated eye M1 The line of line and Shack-Hartmann wavefront sensor M2 and simulated eye M1 is mutually perpendicular to, the light source M3 and beam splitting chip M8 Between be additionally provided with collimation lens M9;The dot chart of optical system wavefront division is obtained by Shack-Hartmann wavefront sensor M2, Slope vector of the human eye aberration on dot chart is calculated, detaches in slope vector and the zeroth orders aberration such as tilts, translates, to eliminate optics In system then the integral inclined or translation of aberration by the independent test to spatial light modulator cell electrode, obtains aberration The aberration response matrix of correction space optical modulator;
(4) voltage value signal will be calculated and is sent to the controller, the cell electrode for controlling liquid crystal spatial modulator is driven Dynamic voltage, by changing the driving voltage value being added on liquid crystal cells electrode, so that it may the phase of point-by-point control incident light, Jin Ershi The variation of existing human eyes wave-front optical aberration.
CN201610907657.5A 2016-10-18 2016-10-18 One kind being based on the adjustable simulated eye of spatial light modulator aberration and its aberration adjusting method Active CN106530923B (en)

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