CN106488907B - O-烷基-苯亚甲基胍衍生物及其治疗与错误折叠蛋白质累积有关疾病的治疗用途 - Google Patents

O-烷基-苯亚甲基胍衍生物及其治疗与错误折叠蛋白质累积有关疾病的治疗用途 Download PDF

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CN106488907B
CN106488907B CN201580036468.9A CN201580036468A CN106488907B CN 106488907 B CN106488907 B CN 106488907B CN 201580036468 A CN201580036468 A CN 201580036468A CN 106488907 B CN106488907 B CN 106488907B
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CN106488907A (zh
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菲利普·古德特
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CN201580036468.9A 2014-07-02 2015-07-02 O-烷基-苯亚甲基胍衍生物及其治疗与错误折叠蛋白质累积有关疾病的治疗用途 Expired - Fee Related CN106488907B (zh)

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EP14306076 2014-07-02
EP14306076.2 2014-07-02
PCT/EP2015/065162 WO2016001390A1 (en) 2014-07-02 2015-07-02 O-alkyl-benzylideneguanidine derivatives and therapeutic use for the treatment of disorders associated an accumulation of misfolded proteins

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CN106488907B true CN106488907B (zh) 2021-01-29

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KR102572217B1 (ko) 2015-04-08 2023-08-28 유나이티드 킹덤 리서치 앤드 이노베이션 포스파타제 선택적 및 비 선택적 포스파타제 억제제의 선별 방법
US20180230105A1 (en) 2017-01-13 2018-08-16 Regents Of The University Of Minnesota Therapeutic compounds
US20210177814A1 (en) 2018-05-09 2021-06-17 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of guanabenz or derivates thereof for the treatment of type i ifn-dependent pathologies
WO2020012339A1 (en) * 2018-07-09 2020-01-16 Glaxosmithkline Intellectual Property Development Limited Chemical compounds
WO2024105168A1 (en) * 2022-11-18 2024-05-23 Inflectis Bioscience Novel combinations useful for the treatments of als
US20240293343A1 (en) 2023-02-13 2024-09-05 Inflectis Bioscience Benzylideneaminoguanidine derivatives as NR2B-selective NMDA receptor antagonists and their therapeutic applications

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