CN106474531A - A kind of suture containing antiseptic and preparation method - Google Patents
A kind of suture containing antiseptic and preparation method Download PDFInfo
- Publication number
- CN106474531A CN106474531A CN201610985759.9A CN201610985759A CN106474531A CN 106474531 A CN106474531 A CN 106474531A CN 201610985759 A CN201610985759 A CN 201610985759A CN 106474531 A CN106474531 A CN 106474531A
- Authority
- CN
- China
- Prior art keywords
- suture
- antiseptic
- solution
- preparation
- silver
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/08—At least partially resorbable materials of animal origin, e.g. catgut, collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/106—Halogens or compounds thereof, e.g. iodine, chlorite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Abstract
A kind of suture containing antiseptic, including：Suture and the antiseptic of antibacterial functions；The antiseptic is the silver-colored one of which such as simple substance and Ag-containing compound, PVP-I, tribromophenol bismuth or several compositions；It is an advantage of the present invention to provide a kind of linear slit zygonema containing antiseptic and preparation method thereof so that the anti-microbial property of operation suture thread can reach long-acting stable effect, so as to reach the purpose for preventing wound infection.The described suture containing antiseptic to achieve these goals, including the antiseptic with long acting antibiotic function and braided suture, as antiseptic is contained on the suture surface of the present invention, therefore has sterilized and antibacterial effect.
Description
Technical field
The invention belongs to medical product technical field, and in particular to a kind of suture containing antiseptic and preparation method.
Background technology
With the development of medical research technology and the summary of experience of clinical practice, although have been set up the anti-of system
Raw element precautionary measures, but surgical site infection (SSIs) is still the complication of great challenge.It is reported that understanding, operative site
Infection (SSIs) probability be usually 2-5%, but the surgical operation of such as colorectum but can above Infection probability rise to
25%.Once wound produces infection, injury generally requires the time delay hospitalization up to 10 days.Therefore, the infection of operative site
Just higher treatment consumption and the loss of excessive medical resource are meaned.In recent years, confirm operative site sense through clinical
Dye (SSIs) is closely relevant with suture, thus the suture with antibacterial effect has been developed that, to reduce bacterium in suture
The adhesion on surface and field planting.Business-like antibacterial suture has Vicryl Plus, Monocryl Plus and PDS at present
The absorbable antibacterial suture such as Plus, these sutures are nontoxic, nonirritant, will not produce unfavorable shadow to wound healing process
Ring, the antibacterial effect with long-acting slow-release, but as price is of a relatively high, therefore should in the extensive of the suture market of China
With also with certain difficulty.For traditional nonabsorable suture, also there is not the antibacterial seam of the marketization
Zygonema.
Specification
For solve above-mentioned technical problem, the present invention frequently with technical scheme as follows：
A kind of suture containing antiseptic, including：Suture and the antiseptic of antibacterial functions.
The antiseptic is one or more in silver-colored or silver ion solution, PVP-I, tribromophenol bismuth.
A kind of preparation method of the suture containing antiseptic, including：
(1) antiseptic is mixed by a certain percentage with water, obtains solution；
(2) suture is impregnated in the solution after mixing, soaks 0.1-24 hour；
（3）Suture after immersion is dehydrated, is dry；
(4) different length specification requirement is pressed, argentiferous suture is carried out cutting, is packed, seals, ethylene oxide sterilizing or irradiation
Sterilization treatment.
It is an advantage of the present invention to provide a kind of linear slit zygonema containing antiseptic and preparation method thereof so that operation stitching
The anti-microbial property of line can reach long-acting stable effect, so as to reach the purpose for preventing wound infection.Described contains antibacterial
The suture of agent to achieve these goals, including the antiseptic with long acting antibiotic function and braided suture, due to this
Antiseptic is contained on bright suture surface, therefore has sterilized and antibacterial effect.
Specific embodiment
A kind of suture containing antiseptic, including：Suture and the antiseptic of antibacterial functions.
The antiseptic is one or more in silver-colored or silver ion solution, PVP-I, tribromophenol bismuth..
A kind of preparation method of the suture containing antiseptic, including：
(1) antiseptic is mixed by a certain percentage with water, solution is obtained, solution is silver or silver ion solution, PVP-I, tribromo
One or more in phenol bismuth；
(2) by suture be impregnated into mix after solution in, soak 0.1-24 hour, suture be silk, cotton thread, linen thread,
A kind of synthetic thread composition therein；
（3）Suture after immersion is dehydrated, is dry；
(4) different length specification requirement is pressed, argentiferous suture is carried out cutting, is packed, seals, ethylene oxide sterilizing or irradiation
Sterilization treatment.
Embodiment 1
(1) silver-colored simple substance is pressed 1 with water:99 ratio is mixed, and obtains silver-colored solution；
(2) suture is impregnated in silver-colored solution, soaks 1 hour,；
（3）Suture after immersion is carried out being dehydrated, is dry；
(4) different length specification requirement is pressed, argentiferous suture is carried out cutting, is packed, seals, ethylene oxide sterilizing or irradiation
Sterilization treatment.
Embodiment 2
(1) 10 are pressed PVP-I with water:90 ratio is mixed, and obtains Betagen Solution；
(2) suture is impregnated in Betagen Solution, soaks 2 hours,；
（3）Suture after immersion is carried out being dehydrated, is dry；
(4) different length specification requirement is pressed, the suture containing PVP-I is carried out cutting, packs, seals, oxirane goes out
Bacterium or irradiation.
Claims (5)
1. a kind of suture containing antiseptic, it is characterised in that：Including：Suture and the antiseptic of antibacterial functions.
2. a kind of preparation method of the as claimed in claim 1 suture containing antiseptic, including：
(1) antiseptic is mixed by a certain percentage with water or other solvents, obtains solution；
(2) suture is impregnated in the solution after mixing, soaks 0.1-24 hour；
(3) suture after immersion is dehydrated, dries；
(4)By different length specification requirement, argentiferous suture is carried out cutting, packed, seal, ethylene oxide sterilizing or irradiation go out Bacterium is processed.
3. according to claim 2 in step (1) solution be silver or silver ion solution, PVP-I, tribromophenol bismuth in one
Plant or several.
4. in step (1), antiseptic with water or other solvents is according to claim 2：0.1:99.9 to 50:50.
5. suture according to claim 2 in step (2) be silk, cotton thread, linen thread, synthetic thread therein a kind of or
Several compositions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610985759.9A CN106474531A (en) | 2016-11-09 | 2016-11-09 | A kind of suture containing antiseptic and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610985759.9A CN106474531A (en) | 2016-11-09 | 2016-11-09 | A kind of suture containing antiseptic and preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106474531A true CN106474531A (en) | 2017-03-08 |
Family
ID=58272333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610985759.9A Pending CN106474531A (en) | 2016-11-09 | 2016-11-09 | A kind of suture containing antiseptic and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106474531A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1093004A (en) * | 1993-03-19 | 1994-10-05 | 蒋建华 | Long-acting broad-spectrum antibacterial medical suture |
| CN1612804A (en) * | 2001-12-03 | 2005-05-04 | C·R·巴德公司 | Microbe-resistant medical device, microbe-resistant polymeric coating and methods for producing same |
| CN2734238Y (en) * | 2004-08-25 | 2005-10-19 | 任晓艳 | Nano silver coated suture line |
| CN1940168A (en) * | 2005-09-29 | 2007-04-04 | 沈鹤柏 | Antibacterial nano-silver medical fibre, its production and use |
| CN101585088A (en) * | 2008-05-21 | 2009-11-25 | 任晓艳 | Method for preparing nano-silver thread |
| CN105251043A (en) * | 2015-10-28 | 2016-01-20 | 钊桂英 | Medical polylactic acid (PLA) suture line and manufacturing method |
-
2016
- 2016-11-09 CN CN201610985759.9A patent/CN106474531A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1093004A (en) * | 1993-03-19 | 1994-10-05 | 蒋建华 | Long-acting broad-spectrum antibacterial medical suture |
| CN1612804A (en) * | 2001-12-03 | 2005-05-04 | C·R·巴德公司 | Microbe-resistant medical device, microbe-resistant polymeric coating and methods for producing same |
| CN2734238Y (en) * | 2004-08-25 | 2005-10-19 | 任晓艳 | Nano silver coated suture line |
| CN1940168A (en) * | 2005-09-29 | 2007-04-04 | 沈鹤柏 | Antibacterial nano-silver medical fibre, its production and use |
| CN101585088A (en) * | 2008-05-21 | 2009-11-25 | 任晓艳 | Method for preparing nano-silver thread |
| CN105251043A (en) * | 2015-10-28 | 2016-01-20 | 钊桂英 | Medical polylactic acid (PLA) suture line and manufacturing method |
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| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170308 |