CN106467891A - A kind of gas supply device being applied to instrument for extracting nucleic acid and instrument for extracting nucleic acid - Google Patents

A kind of gas supply device being applied to instrument for extracting nucleic acid and instrument for extracting nucleic acid Download PDF

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Publication number
CN106467891A
CN106467891A CN201610841516.8A CN201610841516A CN106467891A CN 106467891 A CN106467891 A CN 106467891A CN 201610841516 A CN201610841516 A CN 201610841516A CN 106467891 A CN106467891 A CN 106467891A
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gas
nucleic acid
instrument
pipeline
supply device
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车团结
徐进章
沈颂东
李琳
李亚鹏
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Suzhou Baiyuan Gene Technology Co Ltd
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Suzhou Baiyuan Gene Technology Co Ltd
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor

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  • General Health & Medical Sciences (AREA)
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Abstract

The present invention provides a kind of gas supply device being applied to instrument for extracting nucleic acid and instrument for extracting nucleic acid, and gas supply device includes gas drive, pipeline, heating arrangements, pressure texture, nozzle and controller.Heating arrangements are connected with gas drive by pipeline, for the gas heating in suction heating arrangements;Pressure texture is connected to heating arrangements by pipeline, for will enter pressure texture in gas compression to required air pressure;Nozzle is connected with pressure texture by pipeline;Controller, according to the gas temperature in heating arrangements, to control being turned on and off of heating arrangements.Instrument for extracting nucleic acid includes this gas supply device.Gas is introduced into be heated in heating arrangements and is compressed, gas after compression is injected in extraction column with certain heat, gas heats to extraction column and nucleic acid as thermal source, accelerate extraction column and be heated to temperature required speed, make the temperature in extraction column be in uniform state, reduce the heat needed for heating extraction post.

Description

A kind of gas supply device being applied to instrument for extracting nucleic acid and instrument for extracting nucleic acid
Technical field
The present invention relates to technical field of medical equipment is and in particular to a kind of gas supply device being applied to instrument for extracting nucleic acid And instrument for extracting nucleic acid.
Background technology
The biomacromolecule compound that nucleic acid is become by many nucleotide polymerization, is one of most basic material of life, nucleic acid Be widely present in animal and plant cellss, in microbial body, biological nucleic acid in vivo is often and protein combines to form nucleoprotein.Prior art In to the extracting method of nucleic acid and nucleic acid-extracting apparatus, nucleic acid extraction as disclosed in Chinese patent literature CN101886037A mostly Method and nucleic acid-extracting apparatus.The injection of sample solution containing nucleic acid is mainly located at the top of waste fluid container by extracting method In extraction column, in compressed air injection extraction column, pressure is applied to sample solution, so that sample solution is adsorbed by porous Film, and then adsorb on porous adsorbed film;Afterwards cleaning mixture is injected in extraction column, compressed air is introduced in extraction column, core Acid is retained on the porous adsorbed film of extraction column, for removing other impurity;Again recovered liquid is injected in extraction column, compression is empty Gas is introduced in extraction column, and to apply pressure so that porous adsorbed film and separate nucleic acid, nucleic acid is reclaimed by recovered liquid.With When, to the gas supply device providing compressed air in extraction column, mainly include air pump, the slip-on head being connected with air pump, mobile Setting pressurization mouth on head, the gas of air pump conveying enters pressurization mouth through slip-on head, and finally pressurized mouth is injected in extraction column.
The nucleic acid-extracting apparatus of said structure, during extracting nucleic acid, need extraction column is constantly heated so that core Acid is extracted under preset temperature environment, but, the existing heating arrangement to extraction column, main inclusion opens up several installations The gripper shoe in hole, extraction column is plugged on installation in the hole correspondingly, the bottom of gripper shoe arranges heating plate, heating plate is by heat Amount is transferred to gripper shoe, and gripper shoe transfers heat to extraction column again, and the speed of this heat transfer mode is slowly it is impossible to reach in time Extraction column is heated to temperature required, and, close the gripper shoe side heated temperature height of extraction column by ground, away from gripper shoe The heated temperature in side is low so that the internal temperature of extraction column is uneven, along with the compressed air meeting in injection extraction column Take away a part of heat of extraction column, when extraction column reaches temperature required, institute's calorific requirement, the matter of impact nucleic acid extraction can be increased Amount.
Content of the invention
Therefore, the technical problem to be solved is extraction column heating in nucleic acid-extracting apparatus of the prior art Uneven, and institute's calorific requirement is big.
For this reason, the present invention provides a kind of gas supply device being applied to instrument for extracting nucleic acid, including
Gas drive and some pipelines:
Heating arrangements, have the first air inlet and the first gas outlet, described first air inlet pass through described pipeline with described Gas drive connects, for the gas in heating arrangements described in described gas drive suction is heated to required default temperature Degree;
Pressure texture, its air inlet is connected to the first gas outlet of described heating arrangements by described pipeline, for entering Enter the gas in described pressure texture, be compressed to required air pressure;
Nozzle, is connected with the gas outlet of described pressure texture by described pipeline;And
Controller, according to the gas temperature information in described heating arrangements, to control unlatching or the pass of described heating arrangements Close.
Preferably, the above-mentioned gas supply device being applied to instrument for extracting nucleic acid, also includes reflux pipe, described return duct The one end on road is connected to the described pipeline between described heating arrangements and described pressure texture, and the other end is connected to described heating knot Described first air inlet of structure;And
Temperature sensor, is arranged on the described pipeline between described heating arrangements and described pressure texture, for detecting Gas temperature in this described pipeline;
Valve, is two, be separately positioned on described reflux pipe and, between described heating arrangements and described pressure texture Described pipeline on;
Described controller, according to the detection information of described temperature sensor, controls being turned on and off of two described valves.
Preferably, the above-mentioned gas supply device being applied to instrument for extracting nucleic acid, described heating arrangements include casing, described Open up described first air inlet on the side wall of casing, opposite side wall opens up described first gas outlet;
Heating assembly, is arranged on described box house, for the air heating in described casing.
Preferably, the above-mentioned gas supply device being applied to instrument for extracting nucleic acid, described heating assembly includes
First heated sheet, at least one, opens up several the first pores, is vertically fixed on the interior of described casing Portion, to form several gas passages in the horizontal direction;
Heater element, is laid in the both side surface of described first heated sheet, and avoids described first pore setting.
It is further preferred that the above-mentioned gas supply device being applied to instrument for extracting nucleic acid, also include at least one second Heated sheet, described second heated sheet is fixed on two medial walls of described casing in the horizontal direction, and opens up several the second gas Hole;
Described heater element is also laid in the both side surface of described second heated sheet, and described first heated sheet is along vertically side It is fixed on described casing to through described second heated sheet.
More preferably preferably, the above-mentioned gas supply device being applied to instrument for extracting nucleic acid, described cabinet wall face is laid Heating element heater, and/or
One layer of heat preservation layer is arranged on the outside wall surface of described casing.
It is further preferred that the above-mentioned gas supply device being applied to instrument for extracting nucleic acid, described first heated sheet be to Few two, the second heated sheet is at least two;
In the horizontal direction, it is separated by preset pitch setting between two neighboring described first heated sheet;Vertically, arbitrarily It is separated by prepsetting gap setting between two neighboring described second heated sheet.
Preferably, the above-mentioned gas supply device being applied to instrument for extracting nucleic acid, also includes electromagnetic valve and flow controller, It is arranged on the described pipeline between described pressure texture and described nozzle, described flow controller is used for controlling described electromagnetism The flow of gas in valve.
The present invention also provides a kind of instrument for extracting nucleic acid, including
Gas supply device described in any of the above-described;
Extraction column;
Fixed mechanism, has several installing holes, and described extraction column is plugged on described installation in the hole correspondingly;
Injecting mechanism, for injecting cleaning mixture or recovered liquid in described extraction column;
Heater, is arranged on described fixed mechanism, for heating to described extraction column.
The technical scheme that the present invention provides, has the advantage that:
1. the present invention provide the gas supply device being applied to instrument for extracting nucleic acid, including gas drive, some pipelines, Heating arrangements, pressure texture, nozzle and controller.Wherein, heating arrangements have the first air inlet and the first gas outlet, and first Air inlet is connected with gas drive by pipeline, required for being heated to the gas in gas drive suction heating arrangements Preset temperature;The air inlet of pressure texture is connected to the first gas outlet of heating arrangements by pipeline, for entering compression knot Gas in structure, is compressed to required air pressure;Nozzle is connected with the gas outlet of pressure texture by pipeline;Controller is according to heater Gas temperature information in structure, to control being turned on and off of heating arrangements.
The gas supply device of this structure, during nucleic acid extraction, before gas enters pressure texture, gas is advanced Enter heated in heating arrangements, then the gas of this temperature is compressed, the gas after compression just carries certain heat through spray In mouth injection extraction column, gas heats to the nucleic acid in extraction column and extraction column as thermal source, on the one hand can accelerate to carry Take post to be heated to temperature required speed, on the other hand it is also possible that the temperature in extraction column is in uniform state, reduce Heat needed for heating extraction post.
2. the gas supply device being applied to instrument for extracting nucleic acid that the present invention provides, also includes reflux pipe, temperature sensing Device and two valves, one end of reflux pipe is connected to the pipeline between heating arrangements and described pressure texture, and the other end is even It is connected to the first air inlet of heating arrangement;Temperature sensor is arranged on the pipeline between heating arrangements and pressure texture, is used for Detect the gas temperature in this pipeline;Two valves be separately positioned on reflux pipe and, between heating arrangements and pressure texture Pipeline on;Controller, according to the detection information of temperature sensor, controls being turned on and off of two valves.
The gas supply device of this structure, if temperature sensor detects in the pipeline between heating arrangements and pressure texture The temperature of gas when being not up to preset temperature, controller according to this temperature information, controls the valve on reflux pipe to open, place Valve closing on the pipeline between heating arrangements and pressure texture, the gas in this pipeline enters back into heating through reflux pipe Carry out post bake, until temperature detector detects the gas in the pipeline between heating arrangements and pressure texture in mechanism Till temperature reaches preset temperature, controller turns off the valve on reflux pipe, opens between heating arrangements and pressure texture Pipeline on valve, further ensure that the temperature entering the gas in pressure texture is consistent, enter in extraction column after compression The temperature of gas be consistent, improve the heated uniformity of extraction column.
3. the instrument for extracting nucleic acid that the present invention provides, including above-mentioned any one gas supply device, extraction column, fixing machine Structure, injecting mechanism and heater.Fixed mechanism has several installing holes, and extraction column is plugged on installing hole correspondingly Interior;Injecting mechanism is used in cleaning mixture or recovered liquid injection extraction column;Heater is arranged on fixed mechanism, for institute State extraction column heating.
The extraction apparatus of this structure, the gas supply device using said structure carries so that injecting the gas in extraction column A certain amount of heat, this heat is directly passed to the nucleic acid in extraction column and extraction column, thus accelerating extraction column and nucleic acid It is heated to temperature required speed so that the temperature in extraction column is in uniform state, reduce the heat needed for heating extraction post, Improve the quality of nucleic acid extraction.
Brief description
In order to be illustrated more clearly that the specific embodiment of the invention or technical scheme of the prior art, below will be to concrete In embodiment or description of the prior art the accompanying drawing of required use be briefly described it should be apparent that, below describe in Accompanying drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not paying creative work Put, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is the structural representation of the gas supply device being applied to instrument for extracting nucleic acid provided in the embodiment of the present invention 1 Figure (in figure arrow represents the flow direction of gas);
Fig. 2 is that being applied in the gas supply device of instrument for extracting nucleic acid provided in the embodiment of the present invention 1 first is heated Plate combine with the second heated sheet after structural representation;
Description of reference numerals:1- gas drive;2- pipeline;31- casing;32- first heated sheet;33- second heated sheet; 4- reflux pipe;5- valve;6- temperature sensor;7- controller;8- compressor;9- electromagnetic valve;10- flow controller;11- sprays Mouth.
Specific embodiment
Below in conjunction with accompanying drawing, technical scheme is clearly and completely described with the enforcement it is clear that described Example is a part of embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, ordinary skill The every other embodiment that personnel are obtained under the premise of not making creative work, broadly falls into the scope of protection of the invention.
In describing the invention, it should be noted that term " " center ", " on ", D score, "left", "right", " vertical ", The orientation of instruction such as " level ", " interior ", " outward " or position relationship are based on orientation shown in the drawings or position relationship, merely to Be easy to describe the present invention and simplify description, rather than instruction or the hint device of indication or element must have specific orientation, With specific azimuth configuration and operation, therefore it is not considered as limiting the invention.
As long as additionally, the non-structure each other of involved technical characteristic in invention described below different embodiments Become conflict just can be combined with each other.
Embodiment 1
The present embodiment 1 provides a kind of gas supply device being applied to instrument for extracting nucleic acid, as Fig. 1 and as shown in Fig. 2 inclusion
Air pump and several pipelines 2;
Heating arrangements include casing 32, two the second heated sheets 33 of 31, two the first heated sheets and heating element heater, casing 31 Side there is the first air inlet, opposite side has the first gas outlet, is connected to air pump by pipeline 2 first air inlet, first Gas outlet is connected to compressor 8 (mentioned below);Two the second heated sheets 33 are fixed on inside the two of casing 31 in the horizontal direction On wall, two the first heated sheets 32 vertically pass through two the second heated sheets 33 to be fixed on the inside of casing 31, two It is separated by preset pitch between first heated sheet 32, between two the second heated sheets 33, be separated by prepsetting gap, such as 5,7 or 8 Etc., the first heated sheet 32 and the second heated sheet 33 open up several first pores and the second pore, respectively with level Direction and vertical direction all form gas passage, the gas passage in grid type in whole casing 31;Heating element heater is then laid on In the both side surface of the first heated sheet 32 and the second heated sheet 33.Meanwhile, the internal face of casing 31 also lays heating element heater, And heat-insulation layer, such as foam are arranged on the outer surface of casing 31;
Compressor 8, its air inlet is connected to the first gas outlet of casing 31 by pipeline 2, for entering in compressor 8 Gas, be compressed to required air pressure;
Nozzle 11, is connected with the gas outlet of compressor 8 by pipeline 2;And
Reflux pipe 4, temperature sensor 6 and two valves 5, one end of reflux pipe 4 is connected to casing 31 and compressor 8 Between pipeline 2, the other end is connected to the first air inlet of casing 31;Temperature sensor 6 be arranged on casing 31 and compressor 8 it Between pipeline 2 on, for detecting the gas temperature in this pipeline 2;Two valves 5 are separately positioned on reflux pipe 4 and casing On pipeline 2 between 31 and compressor 8;Heating element heater is preferably resistive heater, or thermocouple, or of the prior art Other heating element heaters.Temperature sensor 6 is preferably infrared temperature sensor 6;
Controller 7, the on the one hand temperature information according to gas in casing 31, to control whether heating element heater in casing 31 is opened Open or close, the temperature of the gas on the pipeline 2 between casing 31 and compressor 8 is on the other hand detected according to temperature sensor 6 Degree information, to control being turned on and off of two valves 5, so that gas 2 enters in compressor 8 by the road, or through backflow Pipeline 4 is back in casing 31 and carries out post bake;
Nozzle 11, is connected with the gas outlet of compressor 8 by pipeline 2;And
Electromagnetic valve 9 and flow controller 10, are arranged on the pipeline 2 between compressor 8 and nozzle 11, flow controller 10 are used for controlling the flow of gas in electromagnetic valve 9.
The gas supply device of this structure, during nucleic acid extraction, air pump, by extraneous air suction casing 31, enters Enter the gas in casing 31 to circulate in the grid type gas passage that the first heated sheet 32 and the second heated sheet 33 are formed and added Heat, after being heated, the gas outlet through casing 31 for the gas is flowed out, and temperature sensor 6 detects the gas temperature in now pipeline 2, works as gas When the temperature of body reaches preset value, controller 7, by the valve 5 on the pipeline 2 between unlatching casing 31 and compressor 8, closes simultaneously Close the valve 5 on reflux pipe 4, then the gas after heating enters in compressor 8 and is compressed to required air pressure, then through its gas outlet Enter in nozzle 11 with pipeline 2, the gas with temperature is injected in extraction column by nozzle 11, to the core in extraction column and extraction column Acid is heated;If the temperature that temperature sensor 6 detects gas is less than preset temperature, controller 7 controls casing 31 and pressure The valve 5 on pipeline 2 between contracting machine 8 is in closing, and the valve 5 on reflux pipe 4 is in be opened, and now gas is through return duct Road 4 is again introduced in casing 31 carrying out post bake, reaches preset value until temperature sensor 6 detects the gas in pipeline 2 Till, then 2 entering in compressor 8 by the road, so circulation is gone down;In addition, when nozzle 11 does not need to inject gas into extraction column During body, or the gas temperature in casing 31 is higher than preset temperature, or when being maintained at preset temperature for a long time, then controller 7 closes Close heating element heater, then open heating element heater on the contrary, with reducing energy consumption.Meanwhile, electromagnetic valve 9 is controlled to open by flow controller 10 The degree opening, is easy to control the amount of compressed gas in injection extraction column at any time so that the gas flow injecting in each extraction column is most Possibly it is consistent.And, per se with heat, compressed gas are as thermal source to extraction for the compressed gas in entrance extraction column Nucleic acid in post and extraction column is heated, and on the one hand can accelerate extraction column and be heated to temperature required speed, the opposing party Face, it is also possible that the temperature in extraction column is in uniform state, reduces the heat needed for heating extraction post.
As the alternative embodiments of above-mentioned embodiment, flow controller 10 can be other gases in prior art Effusion meter.As deformation, can also be without arranging flow controller 10, only electromagnetic valve 9 need to be set, by above-mentioned total controller 7 To control the flow of electromagnetic valve 9.Or, as deformation, can also be without arranging above-mentioned electromagnetic valve 9 and flow controller 10.
As alternative embodiments, the number of the first heated sheet 32 can also be three, four, five, six etc., In the horizontal direction, preset pitch setting in interval between two neighboring first heated sheet 32, for example, be separated by 5,6,7 etc., Depending on the size of this preset pitch is according to specifically used situation, it is not especially limited.As deformation, the number of the first heated sheet 32 Can also be one.
Similarly, the number of the second heated sheet 33 can also be three, four, five, six etc., vertically, It is separated by prepsetting gap setting, the width of this prepsetting gap is not construed as limiting, according to reality between two the second heated sheets 33 of arbitrary neighborhood Depending on the service condition of border, as deformation, the number of the second heated sheet 33 can also be one.
As alternative embodiments, heat-insulation layer is except for foam, being other insulation materials of the prior art. For example, polyurethane thermal insulation board, or thermal insulation coatings etc..As deformation, above-mentioned heating can also be not provided with casing 31 Above-mentioned heat-insulation layer is not provided with element, and the outside wall surface of casing 31.
Further alternatively, can also be without arranging the second heated sheet 33, only setting the first heated sheet 32, or using existing The heating assembly of other structures in technology is had to replace the first heated sheet 32 and the second heated sheet 33, and heating element heater, it is right to come Air within casing 31 is heated.For example, directly resistive heater is set in casing 31, or is passed through hot water pipeline, Or electromagnetic wave heating element etc..Or, it is not provided with above-mentioned casing 31, and using other heating arrangements, this heater Structure has the first air inlet and the first gas outlet, can be heated to required default temperature to entering its interior gas through the first air inlet Spend.
As alternative embodiments, temperature sensor 6 can also be other temperature sensors 6 of the prior art, example As, microwave thermometric temperature sensor 6, or nuclear magnetic resonance, NMR temperature sensor 6 etc..As deformation, can also be without arranging temperature Sensor 6, valve 5 and reflux pipe 4, gas is put in compressor 8 after heating in casing 31 being compressed processing.
As alternative embodiments, compressor 8 can be replaced other pressure textures of the prior art, only need to will enter Its interior gas compression is to required air pressure.
As the alternative embodiments of air pump, air pump can be replaced other gas drives 1 of the prior art, only needs Extraneous gas is pumped in pipeline 2.
In addition, can adopt existing controller 7 of the prior art for controller 7, only need to realize above-mentioned function is Can, and setting temperature detector in heating arrangements, and the temperature signal detecting is passed to controller 7.
Embodiment 2
The present embodiment provides a kind of instrument for extracting nucleic acid, including any one of embodiment 1 gas supply device,
Extraction column;
Fixed mechanism, has several installing holes, and extraction column is plugged on installation in the hole correspondingly;
Injecting mechanism, for by cleaning mixture or recovered liquid injection extraction column;
Heater, is arranged on fixed mechanism, for heating to extraction column.
The instrument for extracting nucleic acid of this structure, because the gas supply device using offer in embodiment 1 is so that inject extraction column Interior gas carries a certain amount of heat, and this heat is directly passed to the nucleic acid in extraction column and extraction column, thus accelerating to carry Take post and nucleic acid is heated to temperature required speed so that the temperature in extraction column is in uniform state, reduce heating extraction post Required heat, improves the quality of nucleic acid extraction.
Obviously, above-described embodiment is only intended to clearly illustrate example, and the not restriction to embodiment.Right For those of ordinary skill in the art, can also make on the basis of the above description other multi-forms change or Change.There is no need to be exhaustive to all of embodiment.And the obvious change thus extended out or Change among still in the protection domain of the invention.

Claims (9)

1. a kind of gas supply device being applied to instrument for extracting nucleic acid is it is characterised in that include
Gas drive (1) and some pipelines (2):
Heating arrangements, have the first air inlet and the first gas outlet, and described first air inlet passes through described pipeline (2) and described gas Body driver (1) connects, required default for being heated to the gas in heating arrangements described in described gas drive (1) suction Temperature;
Pressure texture, its air inlet is connected to the first gas outlet of described heating arrangements by described pipeline (2), for entering Gas in described pressure texture, is compressed to required air pressure;
Nozzle (11), is connected with the gas outlet of described pressure texture by described pipeline (2);And
Controller (7), according to the gas temperature information in described heating arrangements, to control unlatching or the pass of described heating arrangements Close.
2. the gas supply device being applied to instrument for extracting nucleic acid according to claim 1 it is characterised in that:Also include flowing back Pipeline (4), one end of described reflux pipe (4) is connected to the described pipeline between described heating arrangements and described pressure texture (2), the other end is connected to described first air inlet of described heating arrangement;And
Temperature sensor (6), is arranged on the described pipeline (2) between described heating arrangements and described pressure texture, for examining Survey the gas temperature in this described pipeline (2);
Valve (5), is two, be separately positioned on described reflux pipe (4) upper and, described heating arrangements and described pressure texture it Between described pipeline (2) on;
Described controller (7) according to the detection information of described temperature sensor (6), control two described valves (5) unlatching or Close.
3. the gas supply device being applied to instrument for extracting nucleic acid according to claim 1 and 2 it is characterised in that:Described plus Heat engine structure includes
Casing (31), the side wall of described casing (31) opens up described first air inlet, opposite side wall opens up described First gas outlet;
Heating assembly, is arranged on described casing (31) inside, for the air heating in described casing (31).
4. the gas supply device being applied to instrument for extracting nucleic acid according to claim 3 it is characterised in that:Described heating group Part includes
First heated sheet (32), at least one, opens up several the first pores, is vertically fixed on described casing (31) Inside, to form several gas passages in the horizontal direction;
Heater element, is laid in the both side surface of described first heated sheet (32), and avoids described pore setting.
5. the gas supply device being applied to instrument for extracting nucleic acid according to claim 4 it is characterised in that:Also include at least One the second heated sheet (33), described second heated sheet (33) is fixed on two medial walls of described casing (31) in the horizontal direction On, and open up several the second pores;
Described heater element is also laid in the both side surface of described second heated sheet (33), and described first heated sheet (32) edge is perpendicular Nogata is fixed on described casing (31) to through described second heated sheet (33).
6. the gas supply device being applied to instrument for extracting nucleic acid according to claim 4 or 5 it is characterised in that:Described case Heating element heater is laid on body (31) internal face, and/or
One layer of heat preservation layer is arranged on the outside wall surface of described casing (31).
7. the gas supply device being applied to instrument for extracting nucleic acid according to claim 5 or 6 it is characterised in that:Described One heated sheet (32) is at least two, and the second heated sheet (33) is at least two;
In the horizontal direction, it is separated by preset pitch setting between two neighboring described first heated sheet (32);Vertically, arbitrarily It is separated by prepsetting gap setting between two neighboring described second heated sheet (33).
8. the gas supply device being applied to instrument for extracting nucleic acid according to any one of claim 1-7 it is characterised in that: Also include electromagnetic valve (9) and flow controller (10), be arranged at described between described pressure texture and described nozzle (11) On pipeline (2), described flow controller (10) is used for controlling the flow of the interior gas of described electromagnetic valve (9).
9. a kind of instrument for extracting nucleic acid is it is characterised in that include
Gas supply device as any one of claim 1-8;
Extraction column;
Fixed mechanism, has several installing holes, and described extraction column is plugged on described installation in the hole correspondingly;
Injecting mechanism, for injecting cleaning mixture or recovered liquid in described extraction column;
Heater, is arranged on described fixed mechanism, for heating to described extraction column.
CN201610841516.8A 2016-09-22 2016-09-22 A kind of gas supply device being applied to instrument for extracting nucleic acid and instrument for extracting nucleic acid Pending CN106467891A (en)

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CN112375679A (en) * 2020-11-17 2021-02-19 苏州大学附属第二医院 Cell periodic pressure electric applying device and applying method
CN114317252A (en) * 2021-12-30 2022-04-12 苏州百源基因技术有限公司 Heating device applied to nucleic acid extractor and nucleic acid extractor

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CN108926855A (en) * 2018-08-13 2018-12-04 杭州看啊贸易有限公司 A kind of novel atomizing drying machine
CN112375679A (en) * 2020-11-17 2021-02-19 苏州大学附属第二医院 Cell periodic pressure electric applying device and applying method
CN112375679B (en) * 2020-11-17 2024-04-09 苏州大学附属第二医院 Cell periodic pressure electric applying device and applying method
CN114317252A (en) * 2021-12-30 2022-04-12 苏州百源基因技术有限公司 Heating device applied to nucleic acid extractor and nucleic acid extractor

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