CN106455996B - 用于无创地监测和识别药物效应和相互作用的方法和设备 - Google Patents

用于无创地监测和识别药物效应和相互作用的方法和设备 Download PDF

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Publication number
CN106455996B
CN106455996B CN201580028470.1A CN201580028470A CN106455996B CN 106455996 B CN106455996 B CN 106455996B CN 201580028470 A CN201580028470 A CN 201580028470A CN 106455996 B CN106455996 B CN 106455996B
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drug
substance
diff
subject
marker
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Chinese (zh)
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CN106455996A (zh
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K·H·J·德利莫雷
M·布卢特
R·M·阿尔特斯
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Koninklijke Philips NV
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Koninklijke Philips NV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0015—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by features of the telemetry system
    • A61B5/0022—Monitoring a patient using a global network, e.g. telephone networks, internet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4833—Assessment of subject's compliance to treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6887—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
    • A61B5/6898—Portable consumer electronic devices, e.g. music players, telephones, tablet computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0076—Medicament distribution means
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/13—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
    • G16Z99/00—Subject matter not provided for in other main groups of this subclass
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Physiology (AREA)
  • Multimedia (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
CN201580028470.1A 2014-03-31 2015-03-18 用于无创地监测和识别药物效应和相互作用的方法和设备 Expired - Fee Related CN106455996B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14162834 2014-03-31
EP14162834.7 2014-03-31
PCT/EP2015/055602 WO2015150069A1 (en) 2014-03-31 2015-03-18 Method and device for the non-invasive monitoring and identification of drug effects and interactions

Publications (2)

Publication Number Publication Date
CN106455996A CN106455996A (zh) 2017-02-22
CN106455996B true CN106455996B (zh) 2020-09-29

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Country Status (5)

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US (1) US10555699B2 (enExample)
EP (1) EP3125744A1 (enExample)
JP (1) JP2017516510A (enExample)
CN (1) CN106455996B (enExample)
WO (1) WO2015150069A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105678111B (zh) * 2016-02-01 2018-09-14 西安理工大学 基于植物电信号的作物耐盐性评价方法
US11404147B2 (en) 2017-05-05 2022-08-02 International Business Machines Corporation Treatment recommendations based on drug-to-drug interactions
US10839961B2 (en) * 2017-05-05 2020-11-17 International Business Machines Corporation Identifying drug-to-drug interactions in medical content and applying interactions to treatment recommendations
EP3415137A1 (en) * 2017-06-16 2018-12-19 Koninklijke Philips N.V. Harvesting energy during compression of a pill pack
US20200368531A1 (en) * 2017-07-28 2020-11-26 Galvani Bioelectronics Limited Treatment of eye disorders
WO2019023652A1 (en) * 2017-07-28 2019-01-31 Galvani Bioelectronics Limited TREATMENT OF OCULAR DISORDERS
US10902943B2 (en) 2018-05-17 2021-01-26 International Business Machines Corporation Predicting interactions between drugs and foods
CN110767270A (zh) * 2019-11-01 2020-02-07 南京未来医院研究院有限公司 一种虚拟药物试验系统
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003053503A1 (en) * 2001-12-06 2003-07-03 Alaris Medical Systems, Inc. Co2 monitored drug infusion system
CN101772769A (zh) * 2007-08-02 2010-07-07 诺沃-诺迪斯克有限公司 用于辅助胰岛素给药的营养参数估计
US8150509B2 (en) * 2004-10-21 2012-04-03 Cardiac Pacemakers, Inc. Systems and methods for drug therapy enhancement using expected pharmacodynamic models
CN102737165A (zh) * 2012-06-07 2012-10-17 北京太元通软件科技有限公司 临床用药决策支持系统
US8388530B2 (en) * 2000-05-30 2013-03-05 Vladimir Shusterman Personalized monitoring and healthcare information management using physiological basis functions

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6968375B1 (en) 1997-03-28 2005-11-22 Health Hero Network, Inc. Networked system for interactive communication and remote monitoring of individuals
US6063026A (en) 1995-12-07 2000-05-16 Carbon Based Corporation Medical diagnostic analysis system
US20020095313A1 (en) 2000-09-28 2002-07-18 Haq Mohamed M. Computer system for assisting a physician
US7269516B2 (en) 2001-05-15 2007-09-11 Psychogenics, Inc. Systems and methods for monitoring behavior informatics
US20040078218A1 (en) 2002-10-16 2004-04-22 Ellen Badinelli System and apparatus for a consumer to determine food/medicine interactions on a real-time basis
WO2004036182A2 (en) 2002-10-17 2004-04-29 Control Delivery Systems, Inc. Methods for monitoring treatment of disease
EP1419730A1 (en) 2002-11-18 2004-05-19 Industrial Technology Research Institute Non-invasive apparatus system for monitoring autonomic nervous system and uses thereof
EP1522257A1 (en) 2003-10-02 2005-04-13 Industrial Technology Research Institute Non-invasive apparatus system for monitoring drug hepatoxicity
US7983932B2 (en) * 2004-02-17 2011-07-19 BodyBio, Inc Network and methods for integrating individualized clinical test results and nutritional treatment
WO2008003049A2 (en) * 2006-06-28 2008-01-03 The University Of Utah Research Foundation Distinguishing different drug effects from the electroencephalogram
US8732188B2 (en) * 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US20080234322A1 (en) * 2007-03-20 2008-09-25 University Of Utah Methods and apparatus for drug modeling and displaying drug models
US8758245B2 (en) * 2007-03-20 2014-06-24 Lifescan, Inc. Systems and methods for pattern recognition in diabetes management
DE102007038975A1 (de) * 2007-06-30 2009-01-02 Dräger Medical AG & Co. KG Verfahren und Vorrichtung zum Überwachen eines Patienten während der Narkose und zum Bestimmen eines gemeinsamen Effekts mehrerer Anästhetika
US20100137786A1 (en) * 2008-02-12 2010-06-03 Alferness Clifton A System and method for actively managing type 1 diabetes mellitus on a personalized basis
AU2010217221A1 (en) * 2009-02-26 2011-08-25 Dreamed Diabetes Ltd. Method and system for automatic monitoring of diabetes related treatments
JP5317783B2 (ja) * 2009-03-25 2013-10-16 株式会社東芝 薬剤情報管理装置、薬剤情報管理方法、及び薬剤情報管理システム
WO2011112972A2 (en) 2010-03-11 2011-09-15 Philometron, Inc. Physiological monitor system for determining medication delivery and outcome
US20130179184A1 (en) 2012-01-06 2013-07-11 Katherine L. Hurst Individualized Dosing Technique With Multiple Variables
US9035777B2 (en) * 2012-08-24 2015-05-19 Elwha Llc Computational systems and methods for monitoring medication events including use of a camera and data comparison

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8388530B2 (en) * 2000-05-30 2013-03-05 Vladimir Shusterman Personalized monitoring and healthcare information management using physiological basis functions
WO2003053503A1 (en) * 2001-12-06 2003-07-03 Alaris Medical Systems, Inc. Co2 monitored drug infusion system
US8150509B2 (en) * 2004-10-21 2012-04-03 Cardiac Pacemakers, Inc. Systems and methods for drug therapy enhancement using expected pharmacodynamic models
CN101772769A (zh) * 2007-08-02 2010-07-07 诺沃-诺迪斯克有限公司 用于辅助胰岛素给药的营养参数估计
CN102737165A (zh) * 2012-06-07 2012-10-17 北京太元通软件科技有限公司 临床用药决策支持系统

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Publication number Publication date
US10555699B2 (en) 2020-02-11
WO2015150069A1 (en) 2015-10-08
EP3125744A1 (en) 2017-02-08
JP2017516510A (ja) 2017-06-22
CN106455996A (zh) 2017-02-22
WO2015150069A8 (en) 2016-04-21
US20170027505A1 (en) 2017-02-02

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