CN106421945B - Automatic blood cell seperator system - Google Patents
Automatic blood cell seperator system Download PDFInfo
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- CN106421945B CN106421945B CN201610788102.3A CN201610788102A CN106421945B CN 106421945 B CN106421945 B CN 106421945B CN 201610788102 A CN201610788102 A CN 201610788102A CN 106421945 B CN106421945 B CN 106421945B
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- Prior art keywords
- bag
- blood
- separation
- outlet
- blood cell
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0272—Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/12—Centrifuges in which rotors other than bowls generate centrifugal effects in stationary containers
Abstract
The present invention relates to a kind of automatic blood cell seperator systems, belong to medical blood collection separation equipment technical field.Include: concentrator bowl, rotor is equipped in concentrator bowl, rotor connects centrifugal driving device through concentrator bowl bottom；Rotor is equipped with blood separating mechanism.Structure of the invention is simple, and conveniently moving has a wide range of application.
Description
Technical field
The present invention relates to a kind of automatic blood cell seperator systems, belong to medical blood collection separation equipment technology neck
Domain.
Background technique
Component blood infusion is a kind of effective measures of Modern medical therapy, in recent years clinically using more prevalent.At
Dividing blood includes red blood cell, blood platelet and blood plasma, and various composition blood is because preservation condition requires height, and the holding time is short, acquisition condition
It is required that harsher.The acquisition mode of component blood is divided into two kinds at present: machine list is adopted and collected by hand.Machine list adopt be using into
The automatic blood cell seperator of mouth is acquired, and purity is high can once acquire the component blood of single part or double part, but
Since the donor's quantity for contributing component blood merely is few, and import equipment is expensive, many blood stations because condition limits,
It can not be equipped with, therefore component blood collecting quantity is far from satisfying clinical Treatment need.And collected by hand mode low efficiency, at
Point blood purity and collection rate be not high, bulky for the centrifuge that acquires, and the acquisition time limit of component blood require it is relatively high,
Qualified component blood must can be just prepared in 4~6 hours after whole blood acquires, if exceeding time limit, red blood cell and blood
The quality of slurry is not able to satisfy the requirement of relevant national standard, and the limitation based on equipment and acquisition condition, the acquisition of component blood can only
It is carried out inside blood station.
Both the above acquisition mode is all only limitted to carry out inside blood station.And 90% or more the supply of China's blood used in clinic comes
It is enterprising can not to be placed in blood-collecting car since the equipment volume for being used to carry out blood separation is excessively huge derived from street corner voluntary blood donation
The separation of promoting circulation of blood liquid, most of blood exceed the acquisition time limit of certain component bloods, lead to the significant wastage of component blood, in turn result in and face
The bed wretched insufficiency of component blood.
Summary of the invention
The object of the present invention is to provide a kind of automatic blood cell seperator systems, and structure is simple, conveniently moving, Neng Gouying
For blood-collecting car, the acquisition time limit of component blood ensure that.
Automatic blood cell seperator system of the present invention, comprising: concentrator bowl, concentrator bowl is interior to be equipped with rotor, rotor
Centrifugal driving device is connected through concentrator bowl bottom；Rotor is equipped with blood separating mechanism.
Centrifugal driving device drives rotor rotation, and blood separation is completed in blood separating mechanism work on rotor.
Preferably, blood separating mechanism includes the first separator, and the first separator includes first on rotor
Peristaltic pump, the first peristaltic pump first end are connected to whole blood bag outlet, and it further includes red that the first peristaltic pump second end, which is connected to separation bag entrance,
Cell storage bag, red cell preservation bag entrance are connected to separation bag first outlet；Rotor center be equipped with blood accommodate storehouse, whole blood bag and
Red cell preservation bag, which is placed in, to be accommodated in storehouse；Rotor side is equipped with plate component, and separation bag is placed in plate component.
Preferably, blood separating mechanism further includes the second separator, and the second separator includes collecting bag, and collecting bag enters
Mouth passes through second wriggling this connection separation bag second outlet, collecting bag outlet blood plasma storage bag.
Preferably, separation bag first outlet is located at separation bag side, corresponding separation bag first outlet, and the is equipped in separation bag
One blocks wall wall, and the first blocking wall and separation bag side surround red blood cell transfer passage.
Preferably, first wall is blocked to block wall for bending first.
Preferably, separation bag entrance is between separation bag first outlet and second outlet, separation bag entrance and separation bag
It is equipped with second between second outlet and blocks wall.
Preferably, the separation bag side wall of corresponding separation bag second outlet side and second blocks between wall, is arranged on built-in inserted plate
First training dyke.
Preferably, it is equipped with third between collecting bag entrance and exit and blocks wall.
Preferably, the collecting bag side wall of corresponding collecting bag outlet side and third block wall, and built-in inserted plate is equipped with the second water conservancy diversion
Dam.
Preferably, the pipeline being connected between collecting bag and blood plasma storage bag is connected to transfering bag by three-way connection.
Preferably, blood separating mechanism is symmetrical arranged two groups.
Preferably, plate component includes outer plate and built-in inserted plate, and built-in inserted plate is equipped with plug, is correspondingly arranged on outer plate slotting
Hole, outer plate two sides are equipped with snap-gauge, and corresponding snap-gauge, card slot is arranged in rotor side.
Compared with prior art, the beneficial effects of the present invention are:
(1) by setting rotor, the first peristaltic pump and the second peristaltic pump and separation bag and collecting bag, secondary centrifuging is carried out
Movement realizes being performed fully automatic for whole blood acquisition blood platelet process, avoids the possible pollution of collected by hand, safer,
Collecting efficiency is high, reduces the manipulation strength of staff；
(2) equipment is simple, can be onboard, can be used in blood-collecting car, ensure that acquisition time limit, acquisition behaviour
Make more flexible；
(3) consumables cost is cheap, can be received by most of blood stations.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of one embodiment of the invention,
Fig. 2 is the top view of Fig. 1,
Fig. 3 is that blood flows to schematic diagram in blood separation in Fig. 2,
Fig. 4 is the structural schematic diagram of the plate component of one embodiment of the invention,
Fig. 5 is Fig. 4 centerboard component assembled state figure,
Fig. 6 is the first training dyke working state schematic representation in first time centrifugal action,
Fig. 7 is the second training dyke working state schematic representation in second of centrifugal action,
Fig. 8 is blood separation principle schematic diagram,
Fig. 9 is blood separation consumptive material schematic diagram,
Figure 10 is first time centrifugal action flow chart,
Figure 11 is second of centrifugal action flow chart.
In figure: 11, upper cover 13, concentrator bowl 15, rotor 17, centrifugation motor 18, fixing seat 19, adjustable bottom feet 21,
Pipe valve 29, plate component 31, the wriggling of whole blood storehouse 32, second, the first peristaltic pump 27, are cut at red blood cell storehouse 25 in blood plasma storehouse 23
Pump 33, collecting bag 34, the second training dyke 35, separation bag 36, the first training dyke 37, transfering bag 39, blood plasma storage bag
41, whole blood bag 43, red cell preservation bag 53, three-way connection 55, flow-stopping clip；
29.1, built-in inserted plate 29.2, plug 29.3, snap-gauge 29.4, outer plate；
33.1, collecting bag entrance 33.2, collecting bag outlet 33.3, third block wall；
35.1, separation bag second outlet 35.2, separation bag entrance 35.3, separation bag first outlet 35.4, first block
Wall 35.5, second blocks wall；
39.1, blood plasma storage bag entrance；
41.1, whole blood bag exports；
43.1, red cell preservation bag entrance.
Arrow indicates the flow direction of whole blood and each component blood in Fig. 3；
Arrow in Fig. 6 indicates the flow direction of Platelet-rich plasm in first time centrifugal action；
Arrow in Fig. 7 indicates the flow direction of poor thrombocyte plasma in the second centrifugal action,
Arrow in Fig. 8 indicates the flow direction of whole blood and a component blood.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
As shown in Fig. 1~Figure 11, automatic blood cell seperator system of the present invention characterized by comprising from
Heart cylinder 13, concentrator bowl 13 is interior to be equipped with rotor 15, and rotor 15 connects centrifugal driving device through 13 bottom of concentrator bowl；It is set on rotor 15
There is a blood separating mechanism, 13 upper buckle of concentrator bowl closes lid 11, in the inner cavity that rotor 15 is located at concentrator bowl 13 and upper cover 11 surrounds.
Centrifugal driving device is mounted in fixing seat 18, and 18 bottom of fixing seat is equipped with adjustable bottom feet 19.Centrifugal driving device can for from
Electrocardiograph 17.
Blood separating mechanism includes the first separator, and the first separator includes the first peristaltic pump on rotor 15
25,25 first end of the first peristaltic pump is connected to whole blood bag outlet 41.1, and 25 second end of the first peristaltic pump is connected to separation bag entrance 35.2,
It further include red cell preservation bag 43, red cell preservation bag entrance 43.1 is connected to separation bag first outlet 35.3；15 center of rotor is set
There is blood to accommodate storehouse, whole blood bag 41 and red cell preservation bag 43, which are placed in, to be accommodated in storehouse；Blood plasma storehouse 21, red can be divided by accommodating storehouse
Cell storehouse 23 and whole blood storehouse 31；In the course of work, whole blood bag 41 is placed into whole blood storehouse 31, and blood plasma storage bag 39 is placed into blood plasma
In storehouse 21, red cell preservation bag 43 is placed into red blood cell storehouse 23.
15 side of rotor is equipped with plate component 29, and separation bag 35 is placed in plate component 29.
Blood separating mechanism further includes the second separator, and the second separator includes collecting bag 33, collecting bag entrance
33.1 are connected to separation bag second outlet 35.1,33.2 connection blood plasma storage bag entrance of collecting bag outlet by the second peristaltic pump 32
39.1.Separation bag first outlet 35.3 is located at 35 side of separation bag, corresponds to separation bag first outlet 35.3, is equipped in separation bag 35
First blocks wall 35.4, and the first blocking wall 35.4 and 35 side of separation bag surround red blood cell transfer passage.First blocks wall 35.4
Wall is blocked for bending first.Separation bag entrance 35.2 be located at separation bag first outlet 35.3 and separation bag second outlet 35.1 it
Between, it is equipped with second between separation bag entrance 35.2 and separation bag second outlet 35.1 and blocks wall 35.5.Corresponding separation bag second goes out
35 side wall of separation bag of 35.1 sides of mouth and second blocks between wall 35.5, and the first training dyke 36 is arranged on built-in inserted plate 29.1.It collects
Third, which is equipped with, between bag entrance 33.1 and collecting bag outlet 33.2 blocks wall 33.3.Corresponding collecting bag exports the collecting bag of 33.2 sides
33 side walls and third block wall 33.3, and built-in inserted plate 29.1 is equipped with the second training dyke 34.Collecting bag 33 and blood plasma storage bag 39 it
Between the pipeline that is connected to transfering bag 37 is connected to by three-way connection 53.
Blood separating mechanism is symmetrical arranged two groups.
Plate component 29 includes outer plate 29.4 and built-in inserted plate 29.1, and built-in inserted plate 29.1 is equipped with plug 29.2, outer plate
Jack is correspondingly arranged on 29.4, outer 29.4 two sides of plate are equipped with snap-gauge 29.3, corresponding snap-gauge 29.3, and the setting of 15 side of rotor is inserted
Slot.Centrifugal driving device can be centrifugation motor 17.
The configuration of the present invention is simple is light and handy, can be placed on vehicle and apply, and can be applied directly on blood-collecting car, can want
Whole blood is separated in the time limit asked, ensure that the acquisition time limit of component blood.
Working principle:
(1) centrifugal process acquires component blood: basic principle is centrifugation technique.Centrifugation technique is production when being rotated using objects at high speed
Raw powerful centrifugal force makes the suspended particulate being placed in rotary body that sedimentation or floating occur, thus make certain particulate condensations or with
The separation of other particles.
(2) secondary centrifuging method acquires blood platelet: blood is mainly made of red blood cell, leucocyte, blood platelet and blood plasma, wherein
Red blood cell, leucocyte and blood platelet etc. are suspended in blood plasma, and under the influence of centrifugal force, the different haemocyte of specific gravity can generate point
Layer.
The course of work:
For whole blood after being centrifuged for the first time, heavy red blood cell can be affixed to outer layer, and then sink, and light specific gravity is rich in blood platelet
Blood plasma PRP can be affixed to internal layer, and then float.Similarly, in second of centrifugal process, heavy blood platelet can be affixed to outer layer,
The poor blood plasma PPP of light specific gravity can be affixed to internal layer.
As shown in Figure 10, first time centrifugal action:
(1) all flow-stopping clips 55 are opened, the flow-stopping clip 55 on transfering bag 37 is closed, starting centrifugation motor 17, centrifugation
Motor 17 starts running；After reaching requirement revolving speed, cut pipe valve 27 open, then the first peristaltic pump 25 starts running, by whole blood from
Whole blood bag 41 is pumped into separation bag 35；
(2) under the influence of centrifugal force, whole blood is first layered along 17 radial direction of centrifugation motor, and internal layer, which is that specific gravity is small, to be rich in
Thrombocyte plasma PRP, outer layer are heavy leucocyte and red blood cell；
(3) centrifugal force continue effect under, red blood cell sinks along outer layer, and the conveying of red blood cell below separation bag 35 is logical
Road enters in red cell preservation bag 43；
As shown in figure 11, second of centrifugal action:
(4) Platelet-rich plasm PRP enters below the first training dyke 36 under the action of the second peristaltic pump 32 simultaneously
Into collecting bag 33, the second blocking wall 35.5 and the first training dyke 36 can prevent whole blood and red blood cell to be mixed into rich in blood platelet blood
It starches in PRP；
(5) the Platelet-rich plasm PRP in collecting bag 33 is entered, is layered under the influence of centrifugal force, internal layer
For the small poor thrombocyte plasma PPP of specific gravity, outer layer is heavy blood platelet；
(6) centrifugal force continue effect under, blood platelet sinks along outer layer, and poor thrombocyte plasma PPP is flowed into along pipeline
In blood plasma storage bag 39；
Wherein transfering bag 37 is the use of subsequent preparation cryoprecipitate；After preparation, all flow-stopping clips 55 are closed, are taken out primary
Property consumptive material, separation terminate.
As shown in figure 9, medical disposable material includes whole blood bag 41, red cell preservation bag 43, blood plasma storage bag 39, transfering bag
37, collecting bag 33, separation bag, connecting pipeline, flow-stopping clip, and it is set to whole blood bag 41, red cell preservation bag 43, blood plasma storage bag
39, the interface of transfering bag 37, collecting bag 33,35 entrance and exit of separation bag.
Term is explained: PPP refers to that poor thrombocyte plasma, PRP refer to Platelet-rich plasm.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
To the description in the direction of structure and relative positional relationship in the present invention, such as all around above and below description, not structure
At limitation of the present invention, only for convenience of description.
Claims (9)
1. a kind of automatic blood cell seperator system characterized by comprising concentrator bowl (13), concentrator bowl (13) is interior to be equipped with
Rotor (15), rotor (15) connect centrifugal driving device through concentrator bowl (13) bottom；Rotor (15) is equipped with blood separation dress
It sets；Blood separating mechanism includes the first separator, and the first separator includes the first peristaltic pump on rotor (15)
(25), the first peristaltic pump (25) first end connection whole blood bag outlet (41.1), the first peristaltic pump (25) second end are connected to separation bag
Entrance (35.2), further includes red cell preservation bag (43), and red cell preservation bag entrance (43.1) is connected to separation bag first outlet
(35.3)；Rotor (15) center is equipped with blood and accommodates storehouse, and whole blood bag (41) and red cell preservation bag (43), which are placed in, to be accommodated in storehouse；Turn
Sub (15) side is equipped with plate component (29), and separation bag (35) is placed in plate component (29)；Blood separating mechanism further includes
Two separators, the second separator include collecting bag (33), and collecting bag entrance (33.1) is connected to by the second peristaltic pump (32)
Separation bag second outlet (35.1), collecting bag export (33.2) connection blood plasma storage bag entrance (39.1)；Collecting bag (33) and blood
The pipeline being connected between slurry storage bag (39) passes through three-way connection (53) connection transfering bag (37)；Whole blood bag (41), red blood cell are protected
Depositing bag (43), blood plasma storage bag (39), transfering bag (37), collecting bag (33), separation bag (35) is medical disposable material；Described
Automatic blood cell seperator system, can be used in blood-collecting car, and the whole blood for handling blood-collecting car acquisition in time carries out ingredient point
From.
2. automatic blood cell seperator system according to claim 1, which is characterized in that separation bag first outlet
(35.3) it is located at separation bag (35) side, corresponding separation bag first outlet (35.3), separation bag (35) is interior to be equipped with the first blocking wall
(35.4), first blocking wall (35.4) and separation bag (35) side surrounds red blood cell transfer passage.
3. automatic blood cell seperator system according to claim 2, which is characterized in that first block wall (35.4) be
Bending first blocks wall.
4. automatic blood cell seperator system according to claim 1, which is characterized in that separation bag entrance (35.2) position
Between separation bag first outlet (35.3) and separation bag second outlet (35.1), separation bag entrance (35.2) and separation bag second
It exports and is equipped with the second blocking wall (35.5) between (35.1).
5. automatic blood cell seperator system according to claim 4, which is characterized in that corresponding separation bag second outlet
(35.1) separation bag (35) side wall of side and second blocks between wall (35.5), and the first training dyke is arranged on (29.1) in built-in inserted plate
(36)。
6. automatic blood cell seperator system according to claim 1, which is characterized in that collecting bag entrance (33.1) and
Collecting bag, which exports, is equipped with third blocking wall (33.3) between (33.2).
7. automatic blood cell seperator system according to claim 6, which is characterized in that corresponding collecting bag outlet
(33.2) collecting bag (33) side wall of side and third block wall (33.3), and built-in inserted plate (29.1) is equipped with the second training dyke (34).
8. automatic blood cell seperator system according to claim 1, which is characterized in that blood separating mechanism is symmetrically set
Set two groups.
9. automatic blood cell seperator system according to claim 1, which is characterized in that plate component (29) includes outer
Plate (29.4) and built-in inserted plate (29.1), built-in inserted plate (29.1) are equipped with plug (29.2), are correspondingly arranged on outer plate (29.4)
Jack, outer plate (29.4) two sides are equipped with snap-gauge (29.3), and card slot is arranged in corresponding snap-gauge (29.3) rotor (15) side.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610788102.3A CN106421945B (en) | 2016-08-31 | 2016-08-31 | Automatic blood cell seperator system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610788102.3A CN106421945B (en) | 2016-08-31 | 2016-08-31 | Automatic blood cell seperator system |
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| Publication Number | Publication Date |
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| CN106421945A CN106421945A (en) | 2017-02-22 |
| CN106421945B true CN106421945B (en) | 2019-08-09 |
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| CN201610788102.3A Active CN106421945B (en) | 2016-08-31 | 2016-08-31 | Automatic blood cell seperator system |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114110258B (en) * | 2021-11-19 | 2023-03-31 | 山东中保康医疗器具有限公司 | Blood pipeline attitude control device and blood separator with same |
| CN114289194A (en) * | 2021-12-30 | 2022-04-08 | 昕慕(江苏)生物医药科技有限公司 | Blood component separator and use method |
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| US4146172A (en) * | 1977-10-18 | 1979-03-27 | Baxter Travenol Laboratories, Inc. | Centrifugal liquid processing system |
| US5154716A (en) * | 1990-11-06 | 1992-10-13 | Miles Inc. | Bottom blood bag separation system |
| DE4326886A1 (en) * | 1993-08-11 | 1995-02-16 | Herbert Bock | Device and method for aspirating and processing blood from operating fields |
| CN101374560A (en) * | 2006-01-30 | 2009-02-25 | 甘布罗Bct公司 | Adjusting ph in a method of separating whole blood |
| CN206372330U (en) * | 2016-08-31 | 2017-08-04 | 山东中保康医疗器具有限公司 | Automatic blood cell seperator system |
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| US5370802A (en) * | 1987-01-30 | 1994-12-06 | Baxter International Inc. | Enhanced yield platelet collection systems and methods |
| JP2001252350A (en) * | 2000-03-08 | 2001-09-18 | Terumo Corp | Red blood cell apheresis apparatus |
| US20060226086A1 (en) * | 2005-04-08 | 2006-10-12 | Robinson Thomas C | Centrifuge for blood processing systems |
| EP2576073B1 (en) * | 2010-06-07 | 2018-06-13 | Terumo BCT, Inc. | Multi-unit blood processor with volume prediction |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4146172A (en) * | 1977-10-18 | 1979-03-27 | Baxter Travenol Laboratories, Inc. | Centrifugal liquid processing system |
| US5154716A (en) * | 1990-11-06 | 1992-10-13 | Miles Inc. | Bottom blood bag separation system |
| DE4326886A1 (en) * | 1993-08-11 | 1995-02-16 | Herbert Bock | Device and method for aspirating and processing blood from operating fields |
| CN101374560A (en) * | 2006-01-30 | 2009-02-25 | 甘布罗Bct公司 | Adjusting ph in a method of separating whole blood |
| CN206372330U (en) * | 2016-08-31 | 2017-08-04 | 山东中保康医疗器具有限公司 | Automatic blood cell seperator system |
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