CN106421057A - Preparation method of sterculialychnophora throat-smoothing fermentation lozenge and product thereof - Google Patents

Preparation method of sterculialychnophora throat-smoothing fermentation lozenge and product thereof Download PDF

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Publication number
CN106421057A
CN106421057A CN201611209358.0A CN201611209358A CN106421057A CN 106421057 A CN106421057 A CN 106421057A CN 201611209358 A CN201611209358 A CN 201611209358A CN 106421057 A CN106421057 A CN 106421057A
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fermentation
sterculialychnophora
lozenge
throat
makings
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张超
贾婕
姜岷
方诩
武道吉
马江锋
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Shandong Jianzhu University
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Shandong Jianzhu University
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    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
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    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
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    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
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    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention provides a preparation method of sterculialychnophora throat-smoothing fermentation lozenge and a product thereof. The method comprises the steps that the products are mainly prepared from sterculialychnophora, siraitiagrosvenorii, mint, honeysuckle flower, Chinese olive, licorice, American ginseng, chrysanthemum and dried orange peel. The raw materials are mixed as the fermentation makings after making heating sterilization. And then lactobacillus bulgaricus, streptococcus thermophilus, cordycepsmilitaris and mixed bacteria of beer yeast are inoculated into the fermentation makings according to 3 % -5% of inoculation quantity. Let the fermentation makings ferment for 60 hours at 30 DEG C. After finishing the fermentation and making filtration, add aroma-producing yeast into the fermentation makings according to 1 % -2% of inoculation quantity. And then let the fermentation makings ferment for 48 hours under the same temperature. After finishing the fermentation, filter the fermented liquid. The extract powder can be received after being dried. After being tablet compressed and packed, the lozenge can be received. The preparation method of sterculialychnophora throat-smoothing fermentation lozenge is unique, the quality of the lozenge is stable. The lozenge contains a variety of Chinese herbal medicinal ingredients which are beneficial to human body, among which, sterculialychnophora has the efficacy of clearing heat and moistening lung, and sterculialychnophora has excellent curative effects on lung fire, cough due to dryness and aphonia due to sore throat and so on. Siraitiagrosvenorii, mint and dried orange peel have all excellent curative effects on acute bronchitis and sphagitis.

Description

A kind of preparation method of Semen Sterculiae Lychnophorae cleaning throat and moistening larynx fermentation buccal tablet and products obtained therefrom
Technical field
The present invention relates to a kind of Semen Sterculiae Lychnophorae cleaning throat and moistening larynx ferments, the preparation method of buccal tablet and products obtained therefrom, belong to health product system Standby technical field.
Background technology
Semen Sterculiae Lychnophorae, also known as big hole fruit, SEMEN STERCULIAE LYCHNOPHORAE, sea；Sweet in the mouth, light, cold in nature, there are removing heat from the lung and dissipating phlegm, relieving sore throat to recover voice, intestine moistening to lead to Just function；Cure mainly dry cough without phlegm, pharyngalgia hoarseness, chronic pharyngitiss, the disease such as constipation with heat retention.
Fructus Momordicae sweet in the mouth is cool in nature, return lung, large intestine channel, has functions that nourishing the lung to arrest cough, promoting the production of body fluid to quench thirst, is applied to lung-heat or the dryness of the lung Cough, pertussis and summer-heat fluid deficiency and thirsty etc., in addition with effect of loosening bowel to relieve constipation.Pericarpium Citri Reticulatae acrid in the mouth is bitter, warm in nature, has stomach warming and dissipates Cold, effect of regulating qi-flowing for strengthening spleen, the people of the symptom such as suitable stomach distension, dyspepsia, inappetence, cough ant phlegm eats.Fructus Canarii, Also known as " Fructus Canarii albi ", cause and effect is available for eating raw and gains the name when being in still dark green in fact, mild-natured, sweet in the mouth, puckery, sour, heat clearing away, and sore-throat relieving promotes the production of body fluid, Removing toxic substances, for laryngopharynx swelling and pain, cough, excessive thirst etc..The primary efficacy of Radix Glycyrrhizae has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, emergency Pain relieving, coordinating the actions of various ingredients in a prescription.Peppermint stem and leaf has peat-reek, has dispelling wind and heat pathogens, the sharp clearly head, sore-throat relieving, rash, the work(of dispersing the stagnated live-QI to relieve the stagnation of QI Effect.
Cordyceps militaris (L.) Link., also known as Cordyceps militaris (L.) Link., northern Cordyceps militaris (L.) Link., Cordycepses etc., it is rich in cordycepic acid, cordycepin, Cordyceps polysaccharide etc. Composition；Modern science proves that Cordyceps militaris (L.) Link. not only has special nutritive value, and has obvious medical value, has tonifying the lung and puts down Breathe heavily, improve respiratory system, invigorating the lung and the kidney, enhance immunity, effect of memory.
The presently commercially available product that wets one's whistle, composition is simple, and health-care effect can not meet the needs of consumer's cleaning throat and moistening larynx, with When, its local flavor, mouthfeel often can not meet consumer's needs because Chinese medicine ingredients local flavor is incongruous.
For prior art existing problems, it is an object of the invention to provide a kind of Semen Sterculiae Lychnophorae cleaning throat and moistening larynx fermentation buccal tablet, contain Semen Sterculiae Lychnophorae composition, is aided with other raw material of Chinese medicine and adjuvant is made, and cleaning throat and moistening larynx effect is good, and meanwhile, this product has the gas of mediation Taste and good mouthfeel.
Content of the invention
The preparation method of buccal tablet and products obtained therefrom, gained it is an object of the invention to provide a kind of Semen Sterculiae Lychnophorae cleaning throat and moistening larynx ferments Buccal tablet steady quality, cleaning throat and moistening larynx effect good, meet consumer demand.
Concrete technical scheme is as follows：
（1）, press 5-6：1-2：1-2：The mass ratio of 0.5-1, weighs Semen Sterculiae Lychnophorae, Fructus Momordicae, Herba Menthae, Flos Lonicerae, cleans chopping and uses Gauze wrapped, with the water of gross mass 4-5 times, 90 DEG C are heated decoction 2-3 time, each 0.5-1 hour, obtain decoction liquor；
（2）, in the water of every 1000 mass parts, add following mass parts raw material：Fructus Canarii 40-50, Radix Glycyrrhizae 45-50, Radix Panacis Quinquefolii 15-20, Flos Chrysanthemi 12-15, Pericarpium Citri Reticulatae 10-12,80 DEG C of heating decoct 2-3 time, and each 1-2 hour obtains decoction liquor；
（3）, by step（1）The decoction liquor that obtains, step（2）The decoction liquor obtaining is by 1：1 volume ratio mixing, by mixed liquor The 7-9% of quality adds crystal sugar, in 90 DEG C of heat sterilization 30min, as fermentation base material, then according to the inoculum concentration of 3-5% is to sending out Access Lactobacillus bulgaricus, the mixed vaccine of streptococcus thermophiluss, Cordyceps militaris (L.) Link. fungus and beer yeast in ferment base material, ferment at 30 DEG C 60h, the inoculum concentration according still further to 1-2% after completing to filter of fermenting adds SHENGXIANG yeast in fermentation base material, more at that same temperature Fermentation 48h, by fermentation liquid with 8 layers of filtered through gauze after the completion of fermentation, obtains fermentation liquid；Crystal sugar, lemon is added in above-mentioned fermentation liquid Lemon acid and malic acid, mix homogeneously, wherein, in every 100ml fermentation liquid, add 5-12g crystal sugar, 0.1-0.5g citric acid, 0.01- 0.05g malic acid；Mixed fermentation liquid concentrating under reduced pressure, stands 24 hours, takes supernatant, with 8 layers of filtered through gauze, filtrate concentration Become thick paste, extractum is vacuum dried under conditions of 50～60 DEG C of temperature, vacuum -0.07～-0.09MPa, prepared dry powder；
（4）, tabletting：By step（3）Prepared dry powder is tabletted, and must wet one's whistle buccal tablet；
（5）, packaging：By step（4）The prepared buccal tablet that wets one's whistle is packed, and must wet one's whistle buccal tablet finished product.
In said method, step（3）In, the matter of Lactobacillus bulgaricus, streptococcus thermophiluss, Cordyceps militaris (L.) Link. fungus and beer yeast Amount ratio is 2：2：4：2.
The present invention has advantages below：
（1）The inventive method is unique, and technological process is simple, easy to operate, low cost, the pure sky of gained Semen Sterculiae Lychnophorae buccal tablet for clearing and moistening throat So, green product, does not have any toxic and side effects to human body.
（2）Clearing heat and moistening lung of the present invention, cough-relieving, sore-throat relieving, for lung-fire cough caused by dryness, pharyngalgia aphonia etc. has good curative effect.
（3）By the effect of microorganism, the effective ingredient in the Chinese medicines such as Semen Sterculiae Lychnophorae can be made preferably to discharge, more have Curative effect beneficial to buccal tablet for clearing and moistening throat.
（4）The buccal tablet that the present invention makes, by the effect of microorganism, improves the content of vitamin B group in product, has Health-care effect.
（5）The presently commercially available product that wets one's whistle, its local flavor, mouthfeel often can not meet because Chinese medicine ingredients local flavor is incongruous Consumer needs, and the present invention solves the inconsistent problem of local flavor, and product has the abnormal smells from the patient of mediation and good mouthfeel.
（6）The use of SHENGXIANG yeast, gives beverage and has a kind of fragrance of uniqueness, be conducive to strengthening the wants of consumer Hope and mouthfeel.
（7）Through the Fermentation of Cordyceps militaris (L.) Link., make to be rich in cordycepin, adenosine, cordycepic acid and Cordyceps polysaccharide in product, permissible Improve body immunity.
（8）Because in raw material, Chinese medicine ingredients are varied, some compositions are suitable for Lactobacillus bulgaricus effect, some one-tenth Divide and be suitable for Cordyceps militaris (L.) Link. fungus effect, by the way of mixed fermentation, being more beneficial in heterogeneity different effective ingredient has pin To property, efficiently discharge.
Specific embodiment
The present invention will be further elaborated below by specific embodiment it should be appreciated that, the description below is only In order to explain the present invention, and it is not limited thereof.
Embodiment 1
1st, 5 are pressed：1：1：0.5 mass ratio, weighs Semen Sterculiae Lychnophorae, Fructus Momordicae, Herba Menthae, Flos Lonicerae, clean chopping gauze wrapped, uses The water that 4 times of gross mass, 90 DEG C of heating decoct 2 times, 1 hour every time, obtain decoction liquor.
2nd, in the water of every 1000 mass parts, add the raw material of following mass parts：Fructus Canarii 40, Radix Glycyrrhizae 45, Radix Panacis Quinquefolii 15, chrysanthemum Spend 10, the 80 DEG C of heating of 12, Pericarpium Citri Reticulatae to decoct 2 times, 2 hours every time, obtain decoction liquor.
3rd, by step（1）The decoction liquor that obtains, step（2）The decoction liquor obtaining is by 1：1 volume ratio mixing, by mixed liquor Quality 7% addition crystal sugar, in 90 DEG C of heat sterilization 30min, as fermentation base material, then according to 3% inoculum concentration is to fermentation Lactobacillus bulgaricus, the mixed vaccine of streptococcus thermophiluss, Cordyceps militaris (L.) Link. fungus and beer yeast is accessed in base material, in 30 DEG C of 60h that ferment, The inoculum concentration according still further to 1% after completing to filter of fermenting adds SHENGXIANG yeast in fermentation base material, then ferments at that same temperature 48h, by fermentation liquid with 8 layers of filtered through gauze after the completion of fermentation, obtains fermentation liquid；Crystal sugar, citric acid is added in above-mentioned fermentation liquid And malic acid, mix homogeneously, wherein, in every 100ml fermentation liquid, add 5g crystal sugar, 0.1g citric acid, 0.01g malic acid；Mixing Fermentation liquid concentrating under reduced pressure afterwards, stands 24 hours, takes supernatant, and with 8 layers of filtered through gauze, filtrate is condensed into thick paste, extractum is existed It is vacuum dried under conditions of 50～60 DEG C of temperature, vacuum -0.07～-0.09MPa, prepared dry powder；Wherein, bulgarian milk bar The mass ratio of bacterium, streptococcus thermophiluss, Cordyceps militaris (L.) Link. fungus and beer yeast is 2：2：4：2.
4th, tabletting：By step（3）Prepared dry powder is tabletted, and must wet one's whistle buccal tablet.
5th, pack：By step（4）The prepared buccal tablet that wets one's whistle is packed, and must wet one's whistle buccal tablet finished product.
Embodiment 2
1st, 6 are pressed： 2： 2：1 mass ratio, weighs Semen Sterculiae Lychnophorae, Fructus Momordicae, Herba Menthae, Flos Lonicerae, clean chopping gauze wrapped, With 5 times of water of gross mass, 90 DEG C of heating decoct 3 times, 0.5 hour every time, obtain decoction liquor.
2nd, in the water of every 1000 mass parts, add the raw material of following mass parts：Fructus Canarii 50, Radix Glycyrrhizae 50, Radix Panacis Quinquefolii 20, chrysanthemum Spend 12, the 80 DEG C of heating of 15, Pericarpium Citri Reticulatae to decoct 3 times, 1 hour every time, obtain decoction liquor.
3rd, by step（1）The decoction liquor that obtains, step（2）The decoction liquor obtaining is by 1：1 volume ratio mixing, by mixed liquor Quality 9% addition crystal sugar, in 90 DEG C of heat sterilization 30min, as fermentation base material, then according to 5% inoculum concentration is to fermentation Lactobacillus bulgaricus, the mixed vaccine of streptococcus thermophiluss, Cordyceps militaris (L.) Link. fungus and beer yeast is accessed in base material, in 30 DEG C of 60h that ferment, The inoculum concentration according still further to 2% after completing to filter of fermenting adds SHENGXIANG yeast in fermentation base material, then ferments at that same temperature 48h, by fermentation liquid with 8 layers of filtered through gauze after the completion of fermentation, obtains fermentation liquid；Crystal sugar, citric acid is added in above-mentioned fermentation liquid And malic acid, mix homogeneously, wherein, in every 100ml fermentation liquid, add 12g crystal sugar, 0.5g citric acid, 0.05g malic acid；Mixed Fermentation liquid concentrating under reduced pressure after conjunction, stands 24 hours, takes supernatant, with 8 layers of filtered through gauze, filtrate is condensed into thick paste, by extractum It is vacuum dried under conditions of 50～60 DEG C of temperature, vacuum -0.07～-0.09MPa, prepared dry powder；Wherein, bulgarian milk The mass ratio of bacillus, streptococcus thermophiluss, Cordyceps militaris (L.) Link. fungus and beer yeast is 2：2：4：2.
4th, tabletting：By step（3）Prepared dry powder is tabletted, and must wet one's whistle buccal tablet.
5th, pack：By step（4）The prepared buccal tablet that wets one's whistle is packed, and must wet one's whistle buccal tablet finished product.

Claims (2)

1. a kind of preparation method of Semen Sterculiae Lychnophorae cleaning throat and moistening larynx fermentation buccal tablet and products obtained therefrom, is characterized in that comprising the following steps：
（1）, press 5-6：1-2：1-2：The mass ratio of 0.5-1, weighs Semen Sterculiae Lychnophorae, Fructus Momordicae, Herba Menthae, Flos Lonicerae, cleans chopping and uses Gauze wrapped, with the water of gross mass 4-5 times, 90 DEG C are heated decoction 2-3 time, each 0.5-1 hour, obtain decoction liquor；
（2）, in the water of every 1000 mass parts, add following mass parts raw material：Fructus Canarii 40-50, Radix Glycyrrhizae 45-50, Radix Panacis Quinquefolii 15-20, Flos Chrysanthemi 12-15, Pericarpium Citri Reticulatae 10-12,80 DEG C of heating decoct 2-3 time, and each 1-2 hour obtains decoction liquor；
（3）, by step（1）The decoction liquor that obtains, step（2）The decoction liquor obtaining is by 1：1 volume ratio mixing, by mixed liquor The 7-9% of quality adds crystal sugar, in 90 DEG C of heat sterilization 30min, as fermentation base material, then according to the inoculum concentration of 3-5% is to sending out Access Lactobacillus bulgaricus, the mixed vaccine of streptococcus thermophiluss, Cordyceps militaris (L.) Link. fungus and beer yeast in ferment base material, ferment at 30 DEG C 60h, the inoculum concentration according still further to 1-2% after completing to filter of fermenting adds SHENGXIANG yeast in fermentation base material, more at that same temperature Fermentation 48h, by fermentation liquid with 8 layers of filtered through gauze after the completion of fermentation, obtains fermentation liquid；Crystal sugar, lemon is added in above-mentioned fermentation liquid Lemon acid and malic acid, mix homogeneously, wherein, in every 100ml fermentation liquid, add 5-12g crystal sugar, 0.1-0.5g citric acid, 0.01- 0.05g malic acid；Mixed fermentation liquid concentrating under reduced pressure, stands 24 hours, takes supernatant, with 8 layers of filtered through gauze, filtrate concentration Become thick paste, extractum is vacuum dried under conditions of 50～60 DEG C of temperature, vacuum -0.07～-0.09MPa, prepared dry powder；
（4）, tabletting：By step（3）Prepared dry powder is tabletted, and must wet one's whistle buccal tablet；
（5）, packaging：By step（4）The prepared buccal tablet that wets one's whistle is packed, and must wet one's whistle buccal tablet finished product.
2. preparation method according to claim 1, is characterized in that：Step（3）In, Lactobacillus bulgaricus, thermophilus The mass ratio of bacterium, Cordyceps militaris (L.) Link. fungus and beer yeast is 2：2：4：2.
CN201611209358.0A 2016-12-24 2016-12-24 Preparation method of sterculialychnophora throat-smoothing fermentation lozenge and product thereof Pending CN106421057A (en)

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CN108450929A (en) * 2017-12-04 2018-08-28 山东建筑大学 A kind of preparation method and products obtained therefrom of nourishing the liver eyeshield lozenge
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CN107048389A (en) * 2017-05-02 2017-08-18 青岛康迈臣生物科技有限责任公司 Lung-moistening and throat-clearing food and preparation method
CN108450929A (en) * 2017-12-04 2018-08-28 山东建筑大学 A kind of preparation method and products obtained therefrom of nourishing the liver eyeshield lozenge
CN110122650A (en) * 2019-04-25 2019-08-16 沈阳农业大学 A kind of the probiotics fermention cream ice cream lozenge and production method of clearing heat, relieving sore-throat

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