CN106421032A - Pharmaceutical composition for treating rheumatoid arthritis and preparation method thereof - Google Patents
Pharmaceutical composition for treating rheumatoid arthritis and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a pharmaceutical composition for treating rheumatoid arthritis, prepared from Radix Saposhnikoviae, Ramulus Cinnamomi, Radix Clematidis, Herba Siegesbeckiae, Radix Aconiti Sinensis, Radix Aconiti Kusnezoffii, Caulis Piperis Futokasurae, Rhizoma Chuanxiong, Radix Angelicae Dahuricae, Herba Hedyotidis Diffusae, Herba seu Herba Aristolochiae Mollissimae, and Semen Momordicae at a proper ratio; the above medicinal materials are synergistic such that the finally prepared pharmaceutical composition is suitable for moxibustion therapy and Dunhuang health moxibustion, Dunhuang health moxibustion is also referred to as Yin-Yang health moxibustion, the pharmaceutical composition may act for reinforcing yang, resolving dampness, dispelling cold, arresting pain and balancing yin-yang during Dunhuang health moxibustion, the pharmaceutical composition has good and fast effect in treating rheumatic and rheumatoid arthritis, and the problem that the prior art moxa-moxibustion has poor effect and low acting speed is effectively solved.
Description
Technical field
The invention belongs to technical field of pharmaceuticals is and in particular to a kind of pharmaceutical composition treating rheumatic arthritis and its preparation
Method.
Background technology
Rheumatic arthritis are a kind of common acute or chronic ICT, can recurrent exerbation involve heart.
Clinical be characterized with the migrans miserable, pain in joint and muscle, belong to allergic disease, be rheumatic fever main performance it
One, how with febris acuta and arthralgia onset, typical performance is slight or moderate heating, migratory polyarthritis, and involvement is closed
Section mostly is the large joint such as knee joint ankle, shoulder, elbow wrist, common another joint is transferred to by a joint, pathological changes local assumes redness, bright
Heat, severe pain.Some patients also have several joints to fall ill simultaneously, and atypical patient only has arthralgia and no other inflammation tables
Existing, acute inflammation typically disappears in 2-4 week, does not stay sequela, but normal recurrent exerbation.If active rheumatism affects heart, can occur
Myocarditiss even leave valve disorder.
On therapeutic treatment, detumescence, antiinflammatory and analgesic are only rested on to the treatment aspect of rheumatoid diseases at present
Stage, and most of Western medicine is NSAIDS (nonsteroidal anti-inflammatory drugs), antirheumatic and hormone medicine；Chinese medicine is mostly Aconitum carmichjaelii Debx.
The medicines such as pain relieving soup, Radix Tripterygii Wilfordii, patient's such as long-term taking can lead to endocrine regulation, or even it is dirty to damage gastropathy, hepatopathy, nephropathy etc.
The function of device；A lot of patients have been absorbed in the awkward situation of " rheumatism is not also cured, and suffers from the diseases such as serious gastropathy, hepatopathy, nephropathy again ".
For female patient, the medicine such as hormone and Radix Tripterygii Wilfordii also can cause oophoropathy, amenorrhea, impact fertility, also can accelerate to decline simultaneously
Always, effect is extremely limited.
Moxa-moxibustion is a kind of traditional medical therapy of China, the medicine such as the moxa roll of burning or Ai Zhu can make telangiectasis and
Blood flow accelerates, thus blood circulation promoting, makes inflammation absorption, tissue repair.The traditional Chinese medical science thinks that moxa-moxibustion has dispelling cold by warming the meridian, promoting blood circulationization
The stasis of blood, soothing the channels and quicking the network vessels, the function of promoting the circulation of QI to relieve pain.However, the curative effect that existing moxa-moxibustion is used for treating rheumatic arthritis is unsatisfactory,
And onset is slow.
Content of the invention
In order to solve the problems referred to above of prior art presence, the invention provides a kind of good, the rapid-action use of therapeutic effect
Chinese medicine composition in treatment rheumatic arthritis and preparation method thereof.
The technical solution adopted in the present invention is：
A kind of pharmaceutical composition treating rheumatic arthritis, raw material components include：
The careless 40-80 weight portion of Radix Saposhnikoviae 40-80 weight portion, Ramulus Cinnamomi 40-80 weight portion, Radix Clematidis 40-80 weight portion, label,
Radix Aconiti 40-80 weight portion, Radix Aconiti Kusnezoffii 40-80 weight portion, Caulis Piperis Kadsurae 40-80 weight portion, Rhizoma Chuanxiong 40-80 weight portion, Radix Angelicae Dahuricae 40-80 weight
Amount part, Herba Hedyotidis Diffusae 40-80 weight portion, Herba Aristolochiae Mollissimae 40-80 weight portion, Semen Momordicae 10-40 weight portion.
The raw material components of the further preferably described pharmaceutical composition for the treatment of rheumatic arthritis include：Radix Saposhnikoviae 45-55 weight
Amount part, Ramulus Cinnamomi 45-55 weight portion, Radix Clematidis 45-55 weight portion, the careless 45-55 weight portion of label, Radix Aconiti 45-55 weight portion, Radix Aconiti Kusnezoffii
45-55 weight portion, Caulis Piperis Kadsurae 45-55 weight portion, Rhizoma Chuanxiong 45-55 weight portion, Radix Angelicae Dahuricae 45-55 weight portion, Herba Hedyotidis Diffusae 45-55
Weight portion, Herba Aristolochiae Mollissimae 45-55 weight portion, Semen Momordicae 15-25 weight portion.
The raw material components of the further preferably described pharmaceutical composition for the treatment of rheumatic arthritis include：Radix Saposhnikoviae 50 weight
Part, Ramulus Cinnamomi 50 weight portion, Radix Clematidis 50 weight portion, careless 50 weight portions of label, Radix Aconiti 50 weight portion, Radix Aconiti Kusnezoffii 50 weight portion, Caulis Piperis Kadsurae
Rattan 50 weight portion, Rhizoma Chuanxiong 50 weight portion, the Radix Angelicae Dahuricae 50 weight portion, Herba Hedyotidis Diffusae 50 weight portion, Herba Aristolochiae Mollissimae 50 weight portion, Semen Momordicae
20 weight portions.
The raw material components of the further preferably described pharmaceutical composition for the treatment of rheumatic arthritis also include：Rhizoma Atractylodis 20-50
Weight portion, Radix Angelicae Sinensis 20-50 weight portion, Stigma Croci 20-50 weight portion, Semen Strychni 20-50 weight portion, Olibanum 20-50 weight portion, do not have
Medicine 20-50 weight portion.
Further preferably described Rhizoma Atractylodis are 35 weight portions, and described when being classified as 35 weight portions, described Stigma Croci is 40 weight portions,
Described Semen Strychni is 40 weight portions, and described Olibanum is 40 weight portions, and described Myrrha is 40 weight portions.
A kind of preparation method of the described pharmaceutical composition for the treatment of rheumatic arthritis, comprises the steps：
(1) weigh each raw material components, be dried respectively, after pulverization process, obtain each raw material fine powder；
(2) described each raw material fine powder is carried out being sufficiently mixed uniformly, obtain final product the medicine group of described treatment rheumatic arthritis
Compound.
In step (1), the temperature carrying out described drying is 60-90 DEG C, and the time carrying out described drying is 4-6h.
Further preferably, the temperature carrying out described drying is 75 DEG C, and the time carrying out described drying is 5h.
In step (1), the particle diameter of described each raw material fine powder is no more than 200 mesh.
The particle diameter of further preferably described each raw material fine powder is 300 mesh.
For the ease of understanding the present invention, below the raw material in the present invention and drug effect are further elaborated.
Radix Saposhnikoviae, acrid in the mouth, sweet, warm in nature.Inducing diaphoresis to dispel wind, wins wet, relieving convulsion.For headache due to common cold, rheumatic arthralgia, rubella itch,
Tetanus.
Ramulus Cinnamomi, acrid in the mouth, sweet, warm in nature.Sweating expelling pathogenic factors from muscles and skin, promoting the flow of QI-blood by warming the meridian, helps yang transforming qi, flat gas that spins.For anemofrigid cold, gastral cavity
Abdomen cold type of pain, blood trembles with fear Amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Radix Clematidis, acrid in the mouth, salty, warm in nature.Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.For rheumatic arthralgia, numb limbs and tense tendons, muscle arteries and veins contraction,
Joint stuffiness, bone is choked with sobs larynx.
Sign careless, acrid in the mouth, hardship, cold in nature.Wind-damp dispelling, sharp joint, removing toxic substances.For rheumatic arthralgia, muscles and bones is powerless, waist and knee acid
Soft, quadriplegia, hemiplegia, rubella eczema.
Radix Aconiti, acrid in the mouth, hardship, property heat；Very toxic.Expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate
Cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Radix Aconiti Kusnezoffii, acrid in the mouth, hardship, property heat；Very toxic.Expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate
Cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Caulis Piperis Kadsurae, acrid in the mouth, hardship, slightly warm in nature.Wind-damp dispelling, the meridian dredging, stopping numbness pain.For anemofrigid-damp arthralgia, arthrodynia of extremities, tendon and vessel
Contracture, joint stuffiness.
Rhizoma Chuanxiong, acrid in the mouth, warm in nature.Blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, closed dysmenorrhea, lump in the abdomen is suffered from abdominal pain, chest side of body
Twinge, tumbling and swelling, headache, rheumatic arthralgia.
The Radix Angelicae Dahuricae, acrid in the mouth, warm in nature.Scattered wind dehumidifying, sensible pain relieving, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, have a stuffy nose,
Nasal sinusitis, toothache, leucorrhea, sore swell and ache curative.
Herba Hedyotidis Diffusae, sweet in the mouth, light, cool in nature.Heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For acute appendicitis (appendicitis),
Sore furuncle poison, jaundice due to damp-heat, the disease such as dysuria；Furuncle carbuncle, venom are controlled in external.
Herba Aristolochiae Mollissimae, acrid in the mouth, hardship, mild-natured.Dispelling wind and removing obstruction in the collateral, pain relieving.For rheumatic arthralgia, have a stomachache, ball swells and ache, traumatic injury is hindered
The diseases such as pain.
Semen Momordicae, bitter in the mouth, micro-sweet, cool in nature；Poisonous.Mass dissipating and swelling eliminating, counteracting toxic substances treat skin ulcer.For sore swollen toxin, acute mastitis, scrofula,
Anal fistula, chronic eczema, tinea alba.
Rhizoma Atractylodis, acrid in the mouth, hardship, warm in nature.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, tinea pedis
Flaccidity, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Radix Angelicae Sinensis, sweet in the mouth, pungent, warm in nature.Replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizziness palpitaition, the moon
Through uncomfortable, closed dysmenorrhea, asthenia cold abdominalgia, dry constipation of intestines, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.
For closed dysmenorrhea, rheumatic arthralgia, injury from falling down.
Stigma Croci, sweet in the mouth, mild-natured.Blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens.Control troubled thoughts pent-up, chest and diaphragm painful abdominal mass is vexed, spit blood, typhoid fever is gone mad,
Frightened fear in a trance, women's amenorrhea, postnatal blood stasis are suffered from abdominal pain, tumbling and swelling.
Semen Strychni, bitter in the mouth, warm in nature；Very toxic.Removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.For rheumatoid arthritis stubborn, paralysis and numbness, fall and flutter
Damage, ulcer sore pain；Poliomyelitis sequela, rheumatoid arthritis.
Olibanum, acrid in the mouth, hardship, warm in nature.Promoting blood circulation and stopping pain.For all pains of trusted subordinate, muscle arteries and veins contraction, traumatic injury, sore, carbuncle and painful swelling；Outward
Use detumescence and promoting granulation.
Myrrha, bitter in the mouth, mild-natured.Eliminating stasis to stop pain, externally used detumescence granulation promoting.For swell and ache for falling dozen extravasated blood, ulcer sore pain, chest and abdomen are all
Bitterly；External is controlled the open sore part and is not restrained long.
In the present inventor's medical practice, summarize a set of brand-new characteristic moxibustion therapy-Dunhuang healthful moxibustion extracting, Dunhuang health care
The maximum feature of moxibustion is：Spread deposited medicated powder of the present invention in moxibustion area skin, form medicated powder layer, cover on described medicated powder layer afterwards
Gingerbread, medicated powder layer and both gingerbread complement each other, and jointly play a role, and health care effect is good.
Beneficial effects of the present invention are：
The pharmaceutical composition for the treatment of rheumatic arthritis of the present invention, by using Radix Saposhnikoviae, Ramulus Cinnamomi, Radix Clematidis, label
Grass, Radix Aconiti, Radix Aconiti Kusnezoffii, Caulis Piperis Kadsurae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Herba Hedyotidis Diffusae, Herba Aristolochiae Mollissimae and Semen Momordicae are raw material and carry out suitable proportioning,
Above-mentioned all medicines are worked in coordination with and are played a role so that the pharmaceutical composition finally preparing can be used in moxibustion -- Dunhuang healthful moxibustion
In, Dunhuang healthful moxibustion is also referred to as health moxibustion, and in the therapeutic process of Dunhuang healthful moxibustion, described pharmaceutical composition can play
Shake sun, removing dampness, the effect except cold, pain relieving and YIN and YANG balance regulating, for treating rheumatism and rheumatoid arthritiss, good effect, onset
Hurry up, effectively solving moxibustion treatment of the prior art has that weak curative effect, onset are slow；Using treatment of the present invention
The concrete operations that the pharmaceutical composition of rheumatic arthritis carries out moxibustion-Dunhuang healthful moxibustion are：First take drug regimen of the present invention
Thing, adds 8 times of volume Chinese liquor, forms drug immersion liquid, immerses Rhizoma Zingiberis Recenss afterwards and carries out in said medicine soak soaking 48h,
Prepare medicine Rhizoma Zingiberis Recens, then medicine processed with Rhizoma Zingiberis Recens become gingerbread, carry out Dunhuang healthful moxibustion process when, take appropriate described pharmaceutical composition equal
In moxibustion position, spreading thickness is about 0.5-1mm to even spreading, forms medicine layer；Again described gingerbread is placed on medicine layer, it
After take a Ai Zhu to be placed on gingerbread, and Ai Zhu is lighted, when Ai Zhu spontaneous firing to patient has burning sensation cannot stand, separately
A continuous new Ai Zhu, according to state of an illness needs, the number of increase and decrease burning Ai Zhu, until after moxibustion terminates, clean out moxibustion portion
Position, finally plays the sun that shakes, removing dampness, the effect except cold, pain relieving and YIN and YANG balance regulating, for treating rheumatism and rheumatoid joint
Inflammation, good effect, rapid-action.
Specific embodiment
For making the object, technical solutions and advantages of the present invention clearer, technical scheme will be carried out below
Detailed description.Obviously, described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art's obtained owning on the premise of not making creative work
Other embodiment, broadly falls into the scope that the present invention is protected.
In example below, 1g is represented with 1 weight portion.
Embodiment 1
The present embodiment provides a kind of pharmaceutical composition treating rheumatic arthritis, and raw material components include：
Radix Saposhnikoviae 40 weight portion, Ramulus Cinnamomi 80 weight portion, Radix Clematidis 40 weight portion, sign careless 80 weight portions, Radix Aconiti 40 weight portion,
Radix Aconiti Kusnezoffii 80 weight portion, Caulis Piperis Kadsurae 40 weight portion, Rhizoma Chuanxiong 80 weight portion, the Radix Angelicae Dahuricae 40 weight portion, Herba Hedyotidis Diffusae 80 weight portion, seek bone
Wind 40 weight portion, Semen Momordicae 40 weight portion.
Further, the present embodiment provides a kind of preparation method of the pharmaceutical composition of described treatment rheumatic arthritis, including
Following steps：
(1) weigh each raw material components, after being dried 6h at 60 DEG C respectively, carry out pulverization process respectively, obtain particle diameter equal
For each raw material fine powder of 200 purposes；
(2) described each raw material fine powder is carried out being sufficiently mixed uniformly, obtain final product the medicine group of described treatment rheumatic arthritis
Compound.
Embodiment 2
The present embodiment provides a kind of pharmaceutical composition treating rheumatic arthritis, and raw material components include：
Radix Saposhnikoviae 80 weight portion, Ramulus Cinnamomi 40 weight portion, Radix Clematidis 80 weight portion, sign careless 40 weight portions, Radix Aconiti 80 weight portion,
Radix Aconiti Kusnezoffii 40 weight portion, Caulis Piperis Kadsurae 80 weight portion, Rhizoma Chuanxiong 40 weight portion, the Radix Angelicae Dahuricae 80 weight portion, Herba Hedyotidis Diffusae 40 weight portion, seek bone
Wind 80 weight portion, Semen Momordicae 10 weight portion.
Further, the present embodiment provides a kind of preparation method of the pharmaceutical composition of described treatment rheumatic arthritis, including
Following steps：
(1) weigh each raw material components, after being dried 4h at 90 DEG C respectively, carry out pulverization process respectively, obtain particle diameter equal
For each raw material fine powder of 250 purposes；
(2) described each raw material fine powder is carried out being sufficiently mixed uniformly, obtain final product the medicine group of described treatment rheumatic arthritis
Compound.
Embodiment 3
The present embodiment provides a kind of pharmaceutical composition treating rheumatic arthritis, and raw material components include：
Radix Saposhnikoviae 45 weight portion, Ramulus Cinnamomi 55 weight portion, Radix Clematidis 45 weight portion, sign careless 55 weight portions, Radix Aconiti 45 weight portion,
Radix Aconiti Kusnezoffii 55 weight portion, Caulis Piperis Kadsurae 45 weight portion, Rhizoma Chuanxiong 55 weight portion, the Radix Angelicae Dahuricae 45 weight portion, Herba Hedyotidis Diffusae 55 weight portion, seek bone
Wind 45 weight portion, Semen Momordicae 25 weight portion, Rhizoma Atractylodis 20 weight portion, Radix Angelicae Sinensis 50 weight portion, Stigma Croci 20 weight portion, Semen Strychni 50 weight
Amount part, Olibanum 20 weight portion, Myrrha 50 weight portion.
Further, the present embodiment provides a kind of preparation method of the pharmaceutical composition of described treatment rheumatic arthritis, including
Following steps：
(1) weigh each raw material components, after being dried 5h at 75 DEG C respectively, carry out pulverization process respectively, obtain particle diameter equal
For each raw material fine powder of 300 purposes；
(2) described each raw material fine powder is carried out being sufficiently mixed uniformly, obtain final product the medicine group of described treatment rheumatic arthritis
Compound.
Embodiment 4
The present embodiment provides a kind of pharmaceutical composition treating rheumatic arthritis, and raw material components include：
Radix Saposhnikoviae 55 weight portion, Ramulus Cinnamomi 45 weight portion, Radix Clematidis 55 weight portion, sign careless 45 weight portions, Radix Aconiti 55 weight portion,
Radix Aconiti Kusnezoffii 45 weight portion, Caulis Piperis Kadsurae 55 weight portion, Rhizoma Chuanxiong 45 weight portion, the Radix Angelicae Dahuricae 55 weight portion, Herba Hedyotidis Diffusae 45 weight portion, seek bone
Wind 55 weight portion, Semen Momordicae 15 weight portion, Rhizoma Atractylodis 50 weight portion, Radix Angelicae Sinensis 20 weight portion, Stigma Croci 50 weight portion, Semen Strychni 20 weight
Amount part, Olibanum 50 weight portion, Myrrha 20 weight portion.
Further, the present embodiment provides a kind of preparation method of the pharmaceutical composition of described treatment rheumatic arthritis, including
Following steps：
(1) weigh each raw material components, after being dried 5h at 75 DEG C respectively, carry out pulverization process respectively, obtain particle diameter equal
For each raw material fine powder of 350 purposes；
(2) described each raw material fine powder is carried out being sufficiently mixed uniformly, obtain final product the medicine group of described treatment rheumatic arthritis
Compound.
Embodiment 5
The present embodiment provides a kind of pharmaceutical composition treating rheumatic arthritis, and raw material components include：
Radix Saposhnikoviae 50 weight portion, Ramulus Cinnamomi 50 weight portion, Radix Clematidis 50 weight portion, sign careless 50 weight portions, Radix Aconiti 50 weight portion,
Radix Aconiti Kusnezoffii 50 weight portion, Caulis Piperis Kadsurae 50 weight portion, Rhizoma Chuanxiong 50 weight portion, the Radix Angelicae Dahuricae 50 weight portion, Herba Hedyotidis Diffusae 50 weight portion, seek bone
Wind 50 weight portion, Semen Momordicae 20 weight portion, Rhizoma Atractylodis 35 weight portion, Radix Angelicae Sinensis 35 weight portion, Stigma Croci 40 weight portion, Semen Strychni 40 weight
Amount part, Olibanum 40 weight portion, Myrrha 40 weight portion.
Further, the present embodiment provides a kind of preparation method of the pharmaceutical composition of described treatment rheumatic arthritis, including
Following steps：
(1) weigh each raw material components, after being dried 5h at 75 DEG C respectively, carry out pulverization process respectively, obtain particle diameter equal
For each raw material fine powder of 400 purposes；
(2) described each raw material fine powder is carried out being sufficiently mixed uniformly, obtain final product the medicine group of described treatment rheumatic arthritis
Compound.
Pharmaceutical composition using the treatment rheumatic arthritis described in the above embodiment of the present invention 1-5 carries out moxibustion-Dunhuang
Healthful moxibustion, concrete operations are：First take pharmaceutical composition of the present invention, add 8 times of volume Chinese liquor, form drug immersion liquid, it
Afterwards Rhizoma Zingiberis Recenss are immersed and carry out in said medicine soak soaking 48h, prepare medicine Rhizoma Zingiberis Recens, then medicine processed with Rhizoma Zingiberis Recens is become gingerbread, carry out honest
During the process of bright healthful moxibustion, take the uniform spreading of appropriate described pharmaceutical composition in moxibustion position, spreading thickness is about 0.5-
1mm, forms medicine layer；Again described gingerbread is placed on medicine layer, takes a Ai Zhu to be placed on gingerbread afterwards, and by Ai Zhudian
Combustion, when Ai Zhu spontaneous firing to patient has burning sensation cannot stand, separately continues a new Ai Zhu, according to state of an illness needs, increases and decreases
The number of burning Ai Zhu, until after moxibustion terminates, clean out moxibustion position can such that it is able to play the sun that shakes, removing dampness,
Except the effect of cold, pain relieving and YIN and YANG balance regulating, for treating rheumatism and rheumatoid arthritiss, good effect, rapid-action.
Experimental example
The present inventor by applying the observation of this pharmaceutical composition, wherein male to clinical 100 rheumatic arthritis patients
50, women 50, minimum 49 years old of age, maximum 81 years old.
Application process：Moxibustion.
Efficacy assessment standard：
Cure：Clinical efficacy is notable, and symptom is wholly absent, 72.
Effectively：Clinical symptoms are controlled, and symptom is obviously improved, 28.
Total effective rate 100%.
Typical clinical case：
Sun, female, 53 years old, patient articular's pain was more acute, localized pain, pain increase in intensity under coldness, pain alleviated while getting warmth, and local color of the leather is not
Not hot, white and thin fur that is red, touching, stringy and tense pulse, hospital diagnosis are rheumatic and rheumatoid arthritiss arthralgia aggravated by cold disease.Real using the present invention
Apply after the pharmaceutical composition described in example 1 carries out 2 courses for the treatment of of moxibustion, remission, after 3 courses for the treatment of of treatment, symptom is clearly better.
Lee, man, 56 years old, limbs of patient joint aches weighed and do not move, or had swelling, and numbness of the skin is meciless, overcast and rainy plus
Weight or outbreak, tongue is greasy in vain, relaxed and soft pulse, and hospital diagnosis are rheumatic and rheumatoid arthritiss arthralgia aggravated by cold disease, are implemented using the present invention
After pharmaceutical composition described in example 2 carries out 1 course for the treatment of of moxibustion, remission, after 4 courses for the treatment of of treatment, it is almost recovered.
Zhang, man, 63 years old, arthralgia, locally scorching hot redness, bitterly can not touch, joint motion is unfavorable, multiple passes can be involved
Save with fever and aversion to wind, thirsty unhappiness, dry, rough and yellow fur, slippery and rapid pulse, hospital diagnosis are rheumatic and rheumatoid arthritiss pyretic arthralgia disease,
Carried out after 3 courses for the treatment of of moxibustion using the pharmaceutical composition described in the embodiment of the present invention 3, symptom is clearly better.
Liu, female, 64 years old, patient's both legs more than ten years of gonalgia swelling, walking disorder, because of work aggravation, cure
Institute is diagnosed as rheumatism, carries out after 3 courses for the treatment of of moxibustion using the pharmaceutical composition described in the embodiment of the present invention 4, and basic recovery is just
Often.
Beam, man, 63 years old, has a pain during patient's ankle joint, has slight swelling, activity is unfavorable, using the embodiment of the present invention 5
After described pharmaceutical composition carries out moxibustion 3 days, pain relief, after 4 courses for the treatment of of continual cure, recovery from illness.
The above, the only specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, and any
Those familiar with the art the invention discloses technical scope in, change or replacement can be readily occurred in, all should contain
Cover within protection scope of the present invention.Therefore, protection scope of the present invention should be defined by described scope of the claims.
Claims (10)
1. a kind of pharmaceutical composition treating rheumatic arthritis is it is characterised in that raw material components include：
The careless 40-80 weight portion of Radix Saposhnikoviae 40-80 weight portion, Ramulus Cinnamomi 40-80 weight portion, Radix Clematidis 40-80 weight portion, label, Radix Aconiti
40-80 weight portion, Radix Aconiti Kusnezoffii 40-80 weight portion, Caulis Piperis Kadsurae 40-80 weight portion, Rhizoma Chuanxiong 40-80 weight portion, Radix Angelicae Dahuricae 40-80 weight
Part, Herba Hedyotidis Diffusae 40-80 weight portion, Herba Aristolochiae Mollissimae 40-80 weight portion, Semen Momordicae 10-40 weight portion.
2. the pharmaceutical composition for the treatment of rheumatic arthritis according to claim 1 is it is characterised in that raw material components include：
The careless 45-55 weight portion of Radix Saposhnikoviae 45-55 weight portion, Ramulus Cinnamomi 45-55 weight portion, Radix Clematidis 45-55 weight portion, label, Radix Aconiti 45-55
Weight portion, Radix Aconiti Kusnezoffii 45-55 weight portion, Caulis Piperis Kadsurae 45-55 weight portion, Rhizoma Chuanxiong 45-55 weight portion, Radix Angelicae Dahuricae 45-55 weight portion, spend in vain
Herba Hedyotidis Diffusae 45-55 weight portion, Herba Aristolochiae Mollissimae 45-55 weight portion, Semen Momordicae 15-25 weight portion.
3. the pharmaceutical composition for the treatment of rheumatic arthritis according to claim 1 is it is characterised in that raw material components include：
Radix Saposhnikoviae 50 weight portion, Ramulus Cinnamomi 50 weight portion, Radix Clematidis 50 weight portion, careless 50 weight portions of label, Radix Aconiti 50 weight portion, Radix Aconiti Kusnezoffii 50 weight
Amount part, Caulis Piperis Kadsurae 50 weight portion, Rhizoma Chuanxiong 50 weight portion, the Radix Angelicae Dahuricae 50 weight portion, Herba Hedyotidis Diffusae 50 weight portion, Herba Aristolochiae Mollissimae 50 weight
Part, Semen Momordicae 20 weight portion.
4. the pharmaceutical composition of the treatment rheumatic arthritis according to any one of claim 1-3 is it is characterised in that raw material group
Divide and also include：Rhizoma Atractylodis 20-50 weight portion, Radix Angelicae Sinensis 20-50 weight portion, Stigma Croci 20-50 weight portion, Semen Strychni 20-50 weight portion,
Olibanum 20-50 weight portion, Myrrha 20-50 weight portion.
5. the pharmaceutical composition for the treatment of rheumatic arthritis according to claim 4 is it is characterised in that described Rhizoma Atractylodis are 35 weights
Amount part, described when being classified as 35 weight portions, described Stigma Croci is 40 weight portions, and described Semen Strychni is 40 weight portions, and described Olibanum is
40 weight portions, described Myrrha is 40 weight portions.
6. a kind of method of the pharmaceutical composition for the treatment of rheumatic arthritis prepared described in any one of claim 1-5, its feature
It is, comprise the steps：
(1) weigh each raw material components, be dried respectively, after pulverization process, obtain each raw material fine powder；
(2) described each raw material fine powder is carried out being sufficiently mixed uniformly, obtain final product the pharmaceutical composition of described treatment rheumatic arthritis.
7. the preparation method of the pharmaceutical composition for the treatment of rheumatic arthritis according to claim 6 is it is characterised in that step
(1) in, the temperature carrying out described drying is 60-90 DEG C, and the time carrying out described drying is 4-6h.
8. the preparation method of the pharmaceutical composition for the treatment of rheumatic arthritis according to claim 7 is it is characterised in that carry out
The temperature of described drying is 75 DEG C, and the time carrying out described drying is 5h.
9. the preparation method of the pharmaceutical composition for the treatment of rheumatic arthritis according to claim 6 is it is characterised in that step
(1), in, the particle diameter of described each raw material fine powder is no more than 200 mesh.
10. the preparation method of the pharmaceutical composition for the treatment of rheumatic arthritis according to claim 9 is it is characterised in that institute
The particle diameter stating each raw material fine powder is 300 mesh.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611044913.9A CN106421032A (en) | 2016-11-22 | 2016-11-22 | Pharmaceutical composition for treating rheumatoid arthritis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611044913.9A CN106421032A (en) | 2016-11-22 | 2016-11-22 | Pharmaceutical composition for treating rheumatoid arthritis and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101214328A (en) * | 2008-01-04 | 2008-07-09 | 刘会东 | Medicament for treating rheumatism wind-dampness pain and preparation thereof |
| CN101987123A (en) * | 2009-08-05 | 2011-03-23 | 吉林一正药业集团有限公司 | Medicament for easing pain of human body and preparation method thereof |
| CN103432558A (en) * | 2013-09-09 | 2013-12-11 | 王建忠 | Traditional Chinese medicine formula for treating rheumatic arthritis by traditional Chinese medicine fuming moxibustion therapy |
| CN105920610A (en) * | 2016-06-29 | 2016-09-07 | 李野 | Compress ointment matrix, hot compress ointment for treating arthralgia and preparation method of compress ointment matrix and hot compress ointment |
-
2016
- 2016-11-22 CN CN201611044913.9A patent/CN106421032A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101214328A (en) * | 2008-01-04 | 2008-07-09 | 刘会东 | Medicament for treating rheumatism wind-dampness pain and preparation thereof |
| CN101987123A (en) * | 2009-08-05 | 2011-03-23 | 吉林一正药业集团有限公司 | Medicament for easing pain of human body and preparation method thereof |
| CN103432558A (en) * | 2013-09-09 | 2013-12-11 | 王建忠 | Traditional Chinese medicine formula for treating rheumatic arthritis by traditional Chinese medicine fuming moxibustion therapy |
| CN105920610A (en) * | 2016-06-29 | 2016-09-07 | 李野 | Compress ointment matrix, hot compress ointment for treating arthralgia and preparation method of compress ointment matrix and hot compress ointment |
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Application publication date: 20170222 |