CN106389992A - Traditional Chinese medicine preparation for treating frequent micturition and urgent micturition and preparation method of traditional Chinese medicine preparation for treating frequent micturition and urgent micturition - Google Patents
Traditional Chinese medicine preparation for treating frequent micturition and urgent micturition and preparation method of traditional Chinese medicine preparation for treating frequent micturition and urgent micturition Download PDFInfo
- Publication number
- CN106389992A CN106389992A CN201610992111.4A CN201610992111A CN106389992A CN 106389992 A CN106389992 A CN 106389992A CN 201610992111 A CN201610992111 A CN 201610992111A CN 106389992 A CN106389992 A CN 106389992A
- Authority
- CN
- China
- Prior art keywords
- parts
- raw material
- chinese medicine
- medicine preparation
- chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 53
- 239000003814 drug Substances 0.000 title claims abstract description 48
- 230000027939 micturition Effects 0.000 title abstract description 30
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 26
- 108010011485 Aspartame Proteins 0.000 claims abstract description 24
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims abstract description 24
- 229960003438 aspartame Drugs 0.000 claims abstract description 24
- 235000010357 aspartame Nutrition 0.000 claims abstract description 24
- 239000000605 aspartame Substances 0.000 claims abstract description 24
- 210000000582 semen Anatomy 0.000 claims abstract description 20
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims abstract description 19
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 18
- 241000218236 Cannabis Species 0.000 claims abstract description 18
- 239000009636 Huang Qi Substances 0.000 claims abstract description 18
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract description 18
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract description 18
- 235000010234 sodium benzoate Nutrition 0.000 claims abstract description 17
- 239000004299 sodium benzoate Substances 0.000 claims abstract description 17
- 239000002994 raw material Substances 0.000 claims description 85
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 49
- 210000002700 urine Anatomy 0.000 claims description 44
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 35
- 239000000843 powder Substances 0.000 claims description 35
- 235000013399 edible fruits Nutrition 0.000 claims description 34
- 239000007788 liquid Substances 0.000 claims description 22
- 239000000706 filtrate Substances 0.000 claims description 21
- 235000002722 Dioscorea batatas Nutrition 0.000 claims description 17
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims description 17
- 240000001811 Dioscorea oppositifolia Species 0.000 claims description 17
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims description 17
- 241001465251 Ephedra sinica Species 0.000 claims description 17
- 241000488974 Loranthus Species 0.000 claims description 17
- 244000241872 Lycium chinense Species 0.000 claims description 17
- 235000015468 Lycium chinense Nutrition 0.000 claims description 17
- 241000258241 Mantis Species 0.000 claims description 17
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims description 17
- 241001278833 Rosa laevigata Species 0.000 claims description 17
- 235000000661 Rosa laevigata Nutrition 0.000 claims description 17
- 235000011034 Rubus glaucus Nutrition 0.000 claims description 17
- 244000235659 Rubus idaeus Species 0.000 claims description 17
- 235000009122 Rubus idaeus Nutrition 0.000 claims description 17
- 230000003071 parasitic effect Effects 0.000 claims description 17
- 241000205407 Polygonum Species 0.000 claims description 16
- 244000292697 Polygonum aviculare Species 0.000 claims description 16
- 235000006386 Polygonum aviculare Nutrition 0.000 claims description 16
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims description 15
- 238000001914 filtration Methods 0.000 claims description 12
- 241000237502 Ostreidae Species 0.000 claims description 8
- 235000020636 oyster Nutrition 0.000 claims description 8
- 238000009835 boiling Methods 0.000 claims description 7
- 239000006071 cream Substances 0.000 claims description 7
- 230000006837 decompression Effects 0.000 claims description 7
- -1 filters Substances 0.000 claims description 7
- 239000012467 final product Substances 0.000 claims description 7
- 238000004064 recycling Methods 0.000 claims description 7
- 238000005057 refrigeration Methods 0.000 claims description 7
- 238000007789 sealing Methods 0.000 claims description 7
- 230000001954 sterilising effect Effects 0.000 claims description 7
- 238000003756 stirring Methods 0.000 claims description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 238000004806 packaging method and process Methods 0.000 claims description 5
- 229910052708 sodium Inorganic materials 0.000 claims description 5
- 239000011734 sodium Substances 0.000 claims description 5
- 210000003734 kidney Anatomy 0.000 abstract description 22
- 230000007774 longterm Effects 0.000 abstract description 2
- 210000005036 nerve Anatomy 0.000 abstract description 2
- 230000003014 reinforcing effect Effects 0.000 abstract description 2
- 208000004880 Polyuria Diseases 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 description 16
- 235000019634 flavors Nutrition 0.000 description 16
- 208000024891 symptom Diseases 0.000 description 16
- 235000009508 confectionery Nutrition 0.000 description 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 14
- 210000000952 spleen Anatomy 0.000 description 14
- 201000010099 disease Diseases 0.000 description 13
- 230000007812 deficiency Effects 0.000 description 12
- 238000009826 distribution Methods 0.000 description 11
- 210000004185 liver Anatomy 0.000 description 10
- 210000004072 lung Anatomy 0.000 description 9
- 206010011224 Cough Diseases 0.000 description 6
- 206010012735 Diarrhoea Diseases 0.000 description 6
- 210000002784 stomach Anatomy 0.000 description 6
- 230000035900 sweating Effects 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 208000002173 dizziness Diseases 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 208000008967 Enuresis Diseases 0.000 description 4
- 206010030113 Oedema Diseases 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 4
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 4
- 206010046788 Uterine haemorrhage Diseases 0.000 description 4
- 210000001015 abdomen Anatomy 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 206010022437 insomnia Diseases 0.000 description 4
- 230000002269 spontaneous effect Effects 0.000 description 4
- 208000000059 Dyspnea Diseases 0.000 description 3
- 206010013975 Dyspnoeas Diseases 0.000 description 3
- 206010041497 Spermatorrhoea Diseases 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 206010012601 diabetes mellitus Diseases 0.000 description 3
- 208000001848 dysentery Diseases 0.000 description 3
- 206010013990 dysuria Diseases 0.000 description 3
- 210000000936 intestine Anatomy 0.000 description 3
- 210000002429 large intestine Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 201000007094 prostatitis Diseases 0.000 description 3
- 210000003296 saliva Anatomy 0.000 description 3
- 208000013220 shortness of breath Diseases 0.000 description 3
- 238000002562 urinalysis Methods 0.000 description 3
- 210000003932 urinary bladder Anatomy 0.000 description 3
- 230000002485 urinary effect Effects 0.000 description 3
- 230000008673 vomiting Effects 0.000 description 3
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 2
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 description 2
- 206010018612 Gonorrhoea Diseases 0.000 description 2
- 206010059013 Nocturnal emission Diseases 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 206010036790 Productive cough Diseases 0.000 description 2
- 208000012287 Prolapse Diseases 0.000 description 2
- 208000009205 Tinnitus Diseases 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 210000000436 anus Anatomy 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 206010015037 epilepsy Diseases 0.000 description 2
- 210000003414 extremity Anatomy 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 208000035861 hematochezia Diseases 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 210000000629 knee joint Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 208000024794 sputum Diseases 0.000 description 2
- 210000003802 sputum Anatomy 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 231100000886 tinnitus Toxicity 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 208000000143 urethritis Diseases 0.000 description 2
- 239000011800 void material Substances 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 206010000242 Abortion threatened Diseases 0.000 description 1
- 206010006784 Burning sensation Diseases 0.000 description 1
- 241000345998 Calamus manan Species 0.000 description 1
- 208000031868 Calculus ureteric Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 206010018498 Goitre Diseases 0.000 description 1
- 208000004044 Hypesthesia Diseases 0.000 description 1
- 208000006083 Hypokinesia Diseases 0.000 description 1
- 206010021118 Hypotonia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000030852 Parasitic disease Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 208000005985 Threatened Abortion Diseases 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 206010044565 Tremor Diseases 0.000 description 1
- 208000000014 Ureteral Calculi Diseases 0.000 description 1
- 206010046543 Urinary incontinence Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000003356 anti-rheumatic effect Effects 0.000 description 1
- 239000003435 antirheumatic agent Substances 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000013507 chronic prostatitis Diseases 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 208000017561 flaccidity Diseases 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 201000003872 goiter Diseases 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 210000001624 hip Anatomy 0.000 description 1
- 208000006278 hypochromic anemia Diseases 0.000 description 1
- 208000034783 hypoesthesia Diseases 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 201000005630 leukorrhea Diseases 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000001114 myogenic effect Effects 0.000 description 1
- 230000000422 nocturnal effect Effects 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 229940071462 oralone Drugs 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 210000003899 penis Anatomy 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 206010036596 premature ejaculation Diseases 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000012950 rattan cane Nutrition 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000009291 secondary effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 210000003905 vulva Anatomy 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine preparation for treating frequent micturition and urgent micturition and a preparation method of the traditional Chinese medicine preparation for treating frequent micturition and urgent micturition. The traditional Chinese medicine preparation is prepared from, by weight, 300-500 parts of Radix Astragali, 170-230 parts of Fructus Rosae Laevigatae, 170-230 parts of Rhizoma Dioscoreae, 170-230 parts of Nelumbo nucifera Gaerth, 170-230 parts of Fructus Alpiniae Oxyphyllae, 170-230 parts of roasted Semen Ziziphi Spinosae, 50-110 parts of Ootheca Mantidis, 200-400 parts of Caulis et Folium Polygoni Multiflori, 200-400 parts of Herba Taxilli, 200-400 parts of calcined dragon's bones, 120-180 parts of Stamen Nelumbinis, 120-180 parts of Fructus Rubi, 120-180 parts of Fructus Lycii, 10-50 parts of Herba Ephedrae, 10-50 parts of Herba Ephedrae, 300-500 parts of calcined oyster shell, 40-100 parts of Radix Glycyrrhizae, 120-180 parts of Semen Cannabis, 0.001-0.002 part of aspartame and 0.001-0.002 part of sodium benzoate. The traditional Chinese medicine preparation is capable of reinforcing the kidney to strengthen essence and arresting polyuria to calm the nerves, is remarkably effective, can be taken for a long term and is easily accepted by patients.
Description
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of Chinese medicine preparation treating urine urgency-frequency and preparation method.
Background technology
Frequent micturition is two different concepts from urgent urination in Chinese western medicine universities, and frequent micturition is a kind of symptom, not disease
Disease, because many reasons can cause total urination time to increase, but without pain, also known as more the reason frequent urination, frequent micturition, including god
Through mental element, body void after being ill, parasitic disease etc., urinary tract infections, vulva or penis local inflammation etc. except frequent micturition infant is needed,
Urgent urination refers to that patient one has urine to imply that too impatient needs are urinated it is difficult to control；Urine urgency-frequency typically can cause following one
A little harm：1. hyperplasia of prostate：Hyperplasia of prostate is one of common disease of middle-aging male, and dysuria and urine urgency-frequency are
Its common performance symptom；2. urethritis：Urethritis can damage the urethra of the male sex, causes the symptoms such as dysuria, urine urgency-frequency；
3. urinary system infection contamination：Male sex's urine urgency-frequency odynuria is likely to urinary system infection contamination cause of disease complexity, and species is many, uropoiesis sense
Dye is easily sent out crowd and is noted with greater need for more；4. prostatitis：Prostatitis is the common inflammatory disease of male urinary system, is apt to occur in
Lipid on Young-middle Male, patient drips white, urine retention, urine thin, dysuria of line etc., chronic prostatitis after may occur in which frequent micturition, urgent urination, urine
Treatment have certain difficulty, and easy recur；At present, Chinese medicine urine urgency-frequency research report is increasing, because it is secondary
Effect is little to be accepted by vast urine urgency-frequency patient, hence with modern science and technology equipment and method, inquires into the urine urgency-frequency cause of disease
The interpretation of the cause, onset and process of an illness, screening verification active drug, develop Chinese medicine preparation with strong points, that curative effect affirmative, formulation are easy, be currently urgently to be resolved hurrily
Key issue.
Content of the invention
For solving the above problems, the present invention provides a kind of Chinese medicine preparation treating urine urgency-frequency, former by following weight portion
Material is made：Radix Astragali 300-500 part, fruit of Cherokee rose 170-230 part, Chinese yam 170-230 part, black lotus seed 170-230 part, fructus alpiniae oxyphyllae 170-
230 parts, stir-baked SEMEN ZIZIPHI SPINOSAE 170-230 part, mantis egg-case 50-110 part, Polygonum multiflower knotweed 200-400 part, parasitic loranthus 200-400 part, calcined Dragon's bone
200-400 part, stamen nelumbini 120-180 part, raspberry 120-180 part, fruit of Chinese wolfberry 120-180 part, Chinese ephedra 10-50 part, calcined oyster shell
300-500 part, Radix Glycyrrhizae 40-100 part, fructus cannabis 120-180 part, Aspartame 0.001-0.002 part, Sodium Benzoate 0.001-
0.002 part；
The present invention also provides a kind of preparation method of the Chinese medicine preparation treating urine urgency-frequency, and its preparation process is：
（1）The raw material Radix Astragali, the fruit of Cherokee rose, Chinese yam, stamen nelumbini, raspberry, the fruit of Chinese wolfberry, Chinese ephedra, Radix Glycyrrhizae, fructus cannabis is taken to put into pulverizer powder
Broken, cross 50-60 mesh sieve, obtain raw material powder, standby；
（2）Take raw material black lotus seed, fructus alpiniae oxyphyllae, stir-baked SEMEN ZIZIPHI SPINOSAE, mantis egg-case, Polygonum multiflower knotweed, parasitic loranthus to put into pulverizer to pulverize, cross 60-80
Mesh sieve, obtains raw material powder, standby；
（3）Raw material calcined Dragon's bone, calcined oyster shell is taken to be pulverized with pulverizer, smashing fineness is 100-120 mesh, standby；
（4）By step（1）Gained raw material powder and step（2）Gained raw material powder and step（3）Gained pulverize after calcined Dragon's bone, forge male
Oyster adds water to cook three times, adds the water of the 10-12 times amount of raw material weight for the first time, decocts 0.4-1 hour, pours out liquid, second
Plus the water of raw material weight 6-8 times amount, decoct 0.4-1 hour, pour out liquid, the water of third time plus raw material weight 6-8 times amount, decoct
0.4-1 hour, merges three liquids, filters, and filtrate is concentrated into 55-60 DEG C and surveys the clear cream that relative density is 1.08-1.15, plus
The appropriate amount of ethanol of 90-95%, during 5-10 DEG C of standing 24-48, filters, decompression filtrate recycling ethanol is concentrated into no alcohol taste, filtrate
Survey the thick paste that relative density is 1.25-1.35 for 55-60 DEG C, standby；
（5）Raw material Aspartame, Sodium Benzoate is taken to be dissolved into respectively in water, standby；
（6）By step（4）Gained thick paste adds the pure water of its weight 3-5 times amount, adds the Aspartame after dissolving, benzene first
Sour sodium, to being completely dissolved, with centrifugal filtration, revolution 10000-15000r/min, the time is 5-15s to stirring 5-10min, refrigeration,
Standing 24-48 when, then use centrifugal filtration, revolution 16000-20000r/min, the time be 5-15s, be finally packaged in 20ml bottle
Sealing, with the sterilizing of boiling water high temperature 10-15 minute, cooling, packaging, obtains final product the Chinese medicine preparation for the treatment of urine urgency-frequency.
Preferably in scheme, a kind of Chinese medicine preparation treating urine urgency-frequency, it is made up of the raw material of following weight portion：The Radix Astragali
400 parts, 200 parts of the fruit of Cherokee rose, 200 parts of Chinese yam, 200 parts of black lotus seed, 200 parts of fructus alpiniae oxyphyllae, 200 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 80 parts of mantis egg-case, night
Hand over 300 parts of rattan, 300 parts of parasitic loranthus, 300 parts of calcined Dragon's bone, 150 parts of stamen nelumbini, 150 parts of raspberry, 150 parts of the fruit of Chinese wolfberry, 30 parts of Chinese ephedra,
400 parts of calcined oyster shell, 70 parts of Radix Glycyrrhizae, 150 parts of fructus cannabis, 0.0015 part of Aspartame, 0.0015 part of Sodium Benzoate；
Its preparation process is：
（1）The raw material Radix Astragali, the fruit of Cherokee rose, Chinese yam, stamen nelumbini, raspberry, the fruit of Chinese wolfberry, Chinese ephedra, Radix Glycyrrhizae, fructus cannabis is taken to put into pulverizer powder
Broken, cross 50 mesh sieves, obtain raw material powder, standby；
（2）Take raw material black lotus seed, fructus alpiniae oxyphyllae, stir-baked SEMEN ZIZIPHI SPINOSAE, mantis egg-case, Polygonum multiflower knotweed, parasitic loranthus to put into pulverizer to pulverize, cross 60 mesh
Sieve, obtains raw material powder, standby；
（3）Raw material calcined Dragon's bone, calcined oyster shell is taken to be pulverized with pulverizer, smashing fineness is 100 mesh, standby；
（4）By step（1）Gained raw material powder and step（2）Gained raw material powder and step（3）Gained pulverize after calcined Dragon's bone, forge male
Oyster adds water to cook three times, adds the water of 10 times amount of raw material weight for the first time, decocts 0.8 hour, pours out liquid, second plus raw material
The water of weight 8 times amount, decocts 0.8 hour, pours out liquid, the water of third time plus raw material weight 8 times amount, decocts 0.8 hour, merges
Three liquids, filter, and filtrate is concentrated into 55 DEG C and surveys the clear cream that relative density is 1.08, the appropriate amount of ethanol plus 95%, 8 DEG C of standings 24
When, filter, to no alcohol taste, filtrate is concentrated into 60 DEG C and surveys the thick paste that relative density is 1.25 decompression filtrate recycling ethanol, standby；
（5）Raw material Aspartame, Sodium Benzoate is taken to be dissolved into respectively in water, standby；
（6）By step（4）Gained thick paste adds the pure water of its weight 3 times amount, adds the Aspartame after dissolving, benzoic acid
Sodium, 5min is to being completely dissolved for stirring, and with centrifugal filtration, revolution 10000r/min, the time is 5s, refrigeration, during standing 24, then with from
The heart filters, revolution 16000r/min, and the time is 5s, is finally packaged in sealing in 20ml bottle, with the sterilizing in 15 minutes of boiling water high temperature, cold
But, pack, obtain final product the Chinese medicine preparation for the treatment of urine urgency-frequency.
Used by the present invention, the pharmacology of Chinese medicine material medicine is as follows：
The Radix Astragali：Meridian distribution of property and flavor：Sweet, temperature, return lung, the spleen channel；Indication：Invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation；With
In treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, long
Burst and do not hold back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes；Chronic rephrilis protinuria, diabetes.
The fruit of Cherokee rose：Meridian distribution of property and flavor：Sour, sweet, puckery, put down, return kidney, bladder, large intestine channel；Indication：Astringent sperm contracting urine, puckery intestines stop
Rush down；For emission and spermatorrhea, enuresis frequent micturition, uterine bleeding under band, protracted dysentery and diarrhea.
Chinese yam：Meridian distribution of property and flavor：Sweet, put down, returns spleen, lung, kidney channel；Indication：Tonifying spleen nourishing the stomach, engender liquid and benefic lung, the puckery essence of kidney tonifying；
For spleen eating less, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, under band, frequent micturition, and abnormal heat is quenched one's thirst；Rhizoma Dioscoreae (parched with bran) good efficacy to suffering from a deficiency of the kidney；
For spleen eating less, loose stool of having loose bowels, leukorrhea.
Black lotus seed：Nature and flavor：Sweet, puckery, slight bitter, tremble with fear, returns spleen, stomach, the heart, lung channel；Effect：Clearing away damp-heat, whet the appetite the food that spouts, and clears away heart-fire peaceful
God, puckery essence stopping leak；Cure mainly：Dysentery with vomiting, vomiting is not eaten, vexed insomnia, seminal emission, turbid urine, under band.
Fructus alpiniae oxyphyllae：Nature and flavor, taste is pungent, warm in nature, the thoughts of returning home, spleen；Kidney channel；Effect：Warm kidney astringent sperm contracting urine, saliva is taken the photograph in warm spleen appetizing；Main
Control：Deficiency-cold in spleen and stomach, vomiting, have loose bowels, cold in abdomen educate, the many salivas of mouth, enuresis with renal asthenia, frequent micturition, seminal emission, gonorrhoea, the disease such as many salivas.
Stir-baked SEMEN ZIZIPHI SPINOSAE：Meridian distribution of property and flavor：Sweet, sour, put down, Return liver, courage, the heart channel of Hang-Shaoyin；Indication：Tonifying liver, calming heart, arrest sweating, promotes the production of body fluid；With
In restlessness of asrhenia type and insomnia, horrified to much dream, body void hidrosis, injury thirst.
Mantis egg-case：Meridian distribution of property and flavor：Sweet, salty, put down, return liver and kidney channel；Indication：Supplementing the kidney to control the nocturnal, contracting urine, only turbid；For losing
Smart involuntary emission, enuresis frequent micturition, urine gonorrhoea.
Polygonum multiflower knotweed：Meridian distribution of property and flavor：Mild-natured, sweet, slight bitter, the thoughts of returning home, Liver Channel；Indication：Have mental-tranquilization, wind-dispelling,
The function of dredging collateral；Control the diseases such as insomnia and dreamful sleep, deficiency of blood bodily pain, numbness, arthralgia due to wind-dampness, rubella itch.
Parasitic loranthus：Meridian distribution of property and flavor：Bitter, sweet, flat, Return liver, kidney channel；Effect：Wines used as antirheumatic, filling liver kidney, strengthening the bones and muscles, antiabortive；Main
Control：For arthralgia due to wind-dampness, soreness of waist and knee joint, blood under threatened abortion, fetal irritability.
Calcined Dragon's bone：Nature and flavor：Sweet puckery, put down, thoughts of returning home warp, Liver Channel, kidney channel, large intestine channel；Indication：Tranquillizing the mind by relieving convulsion, arrest sweating is solid
Essence, stop blooding puckery intestines, myogenic sore；Control frightened epilepsy demented, palpitation is forgetful, insomnia and dreamful sleep, spontaneous sweating, stranguria with turbid discharge of passing out semen, tell nosebleed and have blood in stool,
Uterine bleeding under band, rush down dysentery prolapse of the anus, ulcer does not close up long.
Stamen nelumbini：Nature and flavor；Sweet, puckery, put down, the thoughts of returning home, kidney channel；Indication：Reinforcing the kidney and controlling noctural emission；For emission and spermatorrhea, under band, urine
Frequently.
Raspberry：Meridian distribution of property and flavor：Sweet, sour, temperature, return kidney, bladder warp；Indication：Kidney-nourishing, controlling nocturnal emission with astringent drugs, contracting urine；For kidney deficiency
The enuresis, frequent urination, impotence and premature ejaculation, emission and spermatorrhea.
The fruit of Chinese wolfberry：Meridian distribution of property and flavor：Sweet, put down, return liver and kidney channel；Indication：Nourishing liver and kidney, benefiting shrewd head；For consumptive disease essence
Lose, soreness of waist and knee joint, dizziness and tinnitus, Heat Diabetes, blood deficiency chlorosis, blurred vision.
Chinese ephedra：Meridian distribution of property and flavor：Pungent, slight bitter, temperature, return lung, bladder warp；Indication：Sweating dissipates cold, freeings lung and relieving asthma, Li Shui
Detumescence；For anemofrigid cold, uncomfortable in chest breath with cough, geomantic omen edema；Bronchial astehma；Herba ephedrae moistens the lung and relieve the cough；It is used for table disease to solve,
Asthma and cough.
Calcined oyster shell：Nature and flavor, taste is salty, cold nature, return liver warp, kidney channel：Indication：Hold back cloudy checking exuberance of yang, the puckery essence of hidroschesis, resolving sputum is soft
Hard；Control frightened epilepsy, spontaneous sweating, seminal emission, stranguria with turbid discharge, uterine bleeding, under band, scrofula, goiter and tumor, dizziness and tinnitus, lump in the abdomen lump in the abdomen, pantothenic acid of having a stomachache；Forge
Oyster convergence is astringent or styptic treatment for spontaneous sweating.
Radix Glycyrrhizae：Mild-natured, sweet, the thoughts of returning home, spleen, lung, stomach；Effect：Help；Indication：Invigorate the spleen and benefit qi, clearing heat and detoxicating,
Expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription；For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs
Contraction urgency pain, carbuncle sore tumefacting virus, alleviate drug toxicity, strong.
Fructus cannabis：Meridian distribution of property and flavor：Sweet, put down, returns spleen, stomach, large intestine channel；Indication：Relax bowel；For blood deficiency and depleted fluid,
Dry constipation of intestines.
Beneficial effects of the present invention：Have functions that to invigorate the kidney and stop nocturnal emission, contracting urine is calmed the nerves, drug effect is notable, can long-term taking, patient
It is easy to accept.
Specific embodiment
Describe technical scheme with reference to embodiment and experimental example in detail, but protection domain not limited to this.
Embodiment 1
A kind of Chinese medicine preparation treating urine urgency-frequency, is made up of the raw material of following weight portion：500 parts of the Radix Astragali, 230 parts of the fruit of Cherokee rose,
230 parts of Chinese yam, 230 parts of black lotus seed, 230 parts of fructus alpiniae oxyphyllae, 230 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 110 parts of mantis egg-case, 400 parts of Polygonum multiflower knotweed, parasitic loranthus
400 parts, 400 parts of calcined Dragon's bone, 180 parts of stamen nelumbini, 180 parts of raspberry, 180 parts of the fruit of Chinese wolfberry, 50 parts of Chinese ephedra, 500 parts of calcined oyster shell, Radix Glycyrrhizae
100 parts, 180 parts of fructus cannabis, 0.002 part of Aspartame, 0.002 part of Sodium Benzoate；
Its preparation process is：
（1）The raw material Radix Astragali, the fruit of Cherokee rose, Chinese yam, stamen nelumbini, raspberry, the fruit of Chinese wolfberry, Chinese ephedra, Radix Glycyrrhizae, fructus cannabis is taken to put into pulverizer powder
Broken, cross 50-60 mesh sieve, obtain raw material powder, standby；
（2）Take raw material black lotus seed, fructus alpiniae oxyphyllae, stir-baked SEMEN ZIZIPHI SPINOSAE, mantis egg-case, Polygonum multiflower knotweed, parasitic loranthus to put into pulverizer to pulverize, cross 60-80
Mesh sieve, obtains raw material powder, standby；
（3）Raw material calcined Dragon's bone, calcined oyster shell is taken to be pulverized with pulverizer, smashing fineness is 100-120 mesh, standby；
（4）By step（1）Gained raw material powder and step（2）Gained raw material powder and step（3）Gained pulverize after calcined Dragon's bone, forge male
Oyster adds water to cook three times, adds the water of the 10-12 times amount of raw material weight for the first time, decocts 0.4-1 hour, pours out liquid, second
Plus the water of raw material weight 6-8 times amount, decoct 0.4-1 hour, pour out liquid, the water of third time plus raw material weight 6-8 times amount, decoct
0.4-1 hour, merges three liquids, filters, and filtrate is concentrated into 55-60 DEG C and surveys the clear cream that relative density is 1.08-1.15, plus
The appropriate amount of ethanol of 90-95%, during 5-10 DEG C of standing 24-48, filters, decompression filtrate recycling ethanol is concentrated into no alcohol taste, filtrate
Survey the thick paste that relative density is 1.25-1.35 for 55-60 DEG C, standby；
（5）Raw material Aspartame, Sodium Benzoate is taken to be dissolved into respectively in water, standby；
（6）By step（4）Gained thick paste adds the pure water of its weight 3-5 times amount, adds the Aspartame after dissolving, benzene first
Sour sodium, to being completely dissolved, with centrifugal filtration, revolution 10000-15000r/min, the time is 5-15s to stirring 5-10min, refrigeration,
Standing 24-48 when, then use centrifugal filtration, revolution 16000-20000r/min, the time be 5-15s, be finally packaged in 20ml bottle
Sealing, with the sterilizing of boiling water high temperature 10-15 minute, cooling, packaging, obtains final product the Chinese medicine preparation for the treatment of urine urgency-frequency.
Usage：Oral, 2 times a day, each 15ml.
Embodiment 2
A kind of Chinese medicine preparation treating urine urgency-frequency, is made up of the raw material of following weight portion：400 parts of the Radix Astragali, 200 parts of the fruit of Cherokee rose,
200 parts of Chinese yam, 200 parts of black lotus seed, 200 parts of fructus alpiniae oxyphyllae, 200 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 80 parts of mantis egg-case, 300 parts of Polygonum multiflower knotweed, parasitic loranthus
300 parts, 300 parts of calcined Dragon's bone, 150 parts of stamen nelumbini, 150 parts of raspberry, 150 parts of the fruit of Chinese wolfberry, 30 parts of Chinese ephedra, 400 parts of calcined oyster shell, Radix Glycyrrhizae
70 parts, 150 parts of fructus cannabis, 0.0015 part of Aspartame, 0.0015 part of Sodium Benzoate；
Its preparation process is：
（1）The raw material Radix Astragali, the fruit of Cherokee rose, Chinese yam, stamen nelumbini, raspberry, the fruit of Chinese wolfberry, Chinese ephedra, Radix Glycyrrhizae, fructus cannabis is taken to put into pulverizer powder
Broken, cross 50-60 mesh sieve, obtain raw material powder, standby；
（2）Take raw material black lotus seed, fructus alpiniae oxyphyllae, stir-baked SEMEN ZIZIPHI SPINOSAE, mantis egg-case, Polygonum multiflower knotweed, parasitic loranthus to put into pulverizer to pulverize, cross 60-80
Mesh sieve, obtains raw material powder, standby；
（3）Raw material calcined Dragon's bone, calcined oyster shell is taken to be pulverized with pulverizer, smashing fineness is 100-120 mesh, standby；
（4）By step（1）Gained raw material powder and step（2）Gained raw material powder and step（3）Gained pulverize after calcined Dragon's bone, forge male
Oyster adds water to cook three times, adds the water of the 10-12 times amount of raw material weight for the first time, decocts 0.4-1 hour, pours out liquid, second
Plus the water of raw material weight 6-8 times amount, decoct 0.4-1 hour, pour out liquid, the water of third time plus raw material weight 6-8 times amount, decoct
0.4-1 hour, merges three liquids, filters, and filtrate is concentrated into 55-60 DEG C and surveys the clear cream that relative density is 1.08-1.15, plus
The appropriate amount of ethanol of 90-95%, during 5-10 DEG C of standing 24-48, filters, decompression filtrate recycling ethanol is concentrated into no alcohol taste, filtrate
Survey the thick paste that relative density is 1.25-1.35 for 55-60 DEG C, standby；
（5）Raw material Aspartame, Sodium Benzoate is taken to be dissolved into respectively in water, standby；
（6）By step（4）Gained thick paste adds the pure water of its weight 3-5 times amount, adds the Aspartame after dissolving, benzene first
Sour sodium, to being completely dissolved, with centrifugal filtration, revolution 10000-15000r/min, the time is 5-15s to stirring 5-10min, refrigeration,
Standing 24-48 when, then use centrifugal filtration, revolution 16000-20000r/min, the time be 5-15s, be finally packaged in 20ml bottle
Sealing, with the sterilizing of boiling water high temperature 10-15 minute, cooling, packaging, obtains final product the Chinese medicine preparation for the treatment of urine urgency-frequency.
Usage：Oral, 2 times a day, each 15ml.
Embodiment 3
A kind of Chinese medicine preparation treating urine urgency-frequency, is made up of the raw material of following weight portion：300 parts of the Radix Astragali, 170 parts of the fruit of Cherokee rose,
170 parts of Chinese yam, 170 parts of black lotus seed, 170 parts of fructus alpiniae oxyphyllae, 170 parts of stir-baked SEMEN ZIZIPHI SPINOSAE, 50 parts of mantis egg-case, 200 parts of Polygonum multiflower knotweed, parasitic loranthus
200 parts, 200 parts of calcined Dragon's bone, 120 parts of stamen nelumbini, 120 parts of raspberry, 120 parts of the fruit of Chinese wolfberry, 10 parts of Chinese ephedra, 300 parts of calcined oyster shell, Radix Glycyrrhizae
40 parts, 120 parts of fructus cannabis, 0.001 part of Aspartame, 0.001 part of Sodium Benzoate；
Its preparation process is：
（1）The raw material Radix Astragali, the fruit of Cherokee rose, Chinese yam, stamen nelumbini, raspberry, the fruit of Chinese wolfberry, Chinese ephedra, Radix Glycyrrhizae, fructus cannabis is taken to put into pulverizer powder
Broken, cross 50-60 mesh sieve, obtain raw material powder, standby；
（2）Take raw material black lotus seed, fructus alpiniae oxyphyllae, stir-baked SEMEN ZIZIPHI SPINOSAE, mantis egg-case, Polygonum multiflower knotweed, parasitic loranthus to put into pulverizer to pulverize, cross 60-80
Mesh sieve, obtains raw material powder, standby；
（3）Raw material calcined Dragon's bone, calcined oyster shell is taken to be pulverized with pulverizer, smashing fineness is 100-120 mesh, standby；
（4）By step（1）Gained raw material powder and step（2）Gained raw material powder and step（3）Gained pulverize after calcined Dragon's bone, forge male
Oyster adds water to cook three times, adds the water of the 10-12 times amount of raw material weight for the first time, decocts 0.4-1 hour, pours out liquid, second
Plus the water of raw material weight 6-8 times amount, decoct 0.4-1 hour, pour out liquid, the water of third time plus raw material weight 6-8 times amount, decoct
0.4-1 hour, merges three liquids, filters, and filtrate is concentrated into 55-60 DEG C and surveys the clear cream that relative density is 1.08-1.15, plus
The appropriate amount of ethanol of 90-95%, during 5-10 DEG C of standing 24-48, filters, decompression filtrate recycling ethanol is concentrated into no alcohol taste, filtrate
Survey the thick paste that relative density is 1.25-1.35 for 55-60 DEG C, standby；
（5）Raw material Aspartame, Sodium Benzoate is taken to be dissolved into respectively in water, standby；
（6）By step（4）Gained thick paste adds the pure water of its weight 3-5 times amount, adds the Aspartame after dissolving, benzene first
Sour sodium, to being completely dissolved, with centrifugal filtration, revolution 10000-15000r/min, the time is 5-15s to stirring 5-10min, refrigeration,
Standing 24-48 when, then use centrifugal filtration, revolution 16000-20000r/min, the time be 5-15s, be finally packaged in 20ml bottle
Sealing, with the sterilizing of boiling water high temperature 10-15 minute, cooling, packaging, obtains final product the Chinese medicine preparation for the treatment of urine urgency-frequency.
Usage：Oral, 2 times a day, each 15ml.
Chinese medicine preparation Ureteral Calculus urine urgency-frequency patient of the present invention 45, clinical report is as follows：
1st, physical data
Clinical observation urine urgency-frequency patient 45, wherein man 30, female 15, age 34-65 year, average age 50.5 years old.
2nd, diagnostic criteria
Cardinal symptom：Frequent micturition, urgent urination.Minor symptom：Burning sensation during urination, the sound of rain pattering not to the utmost, the urinary incontinence, spiritlessness and weakness, soreness and weakness of waist and knees, feelings
Will is not easypro etc..This disease is dialectical, mainly distinguishes the length of the course of disease, the actual situation of syndrome, and the course of disease is short, and fall ill urgency person, mostly damp invasion of lower energizer,
True card；The course of disease is long, and disease comes slow person, mostly spleen kidney qi deficiency, belongs to asthenic symptoms.
3rd, treatment method
Using Chinese medicine preparation of the present invention treatment, oral Chinese medicine preparation of the present invention, 2 times a day, each 15ml, is within 7 days a course for the treatment of.
4th, efficacy evaluation
Cure：Symptom, sign disappear, and routine urinalysis is normal；
Take a turn for the better：Symptom mitigation, sign and routine urinalysis have improvement；
Invalid：Symptom and routine urinalysis are all unchanged.
5th, treatment results
In clinical treatment urine urgency-frequency patient 45, cure 30 and account for 66.7%, taking a turn for the better 15 accounts for 33.3%, invalid 0, always effectively
Rate is 100%.
6th, model case
Case 1：Man, 34 years old, happened suddenly urine urgency-frequency symptom, and with the soreness of waist, weak, shortness of breath is dizzy, oral Chinese medicine preparation of the present invention
One course for the treatment of, patient symptom substantially mitigates, and one course for the treatment of of oral traditional Chinese medicine preparation, and symptom is clearly better, and is administered orally in the present invention again
One course for the treatment of of medicine preparation, clinical cure.
Case 2：Female, 40 years old, main frequent micturition, urgent urination 1 year, increase 5 days, with the soreness of waist, weak, shortness of breath, dizzy, edema, mouth
Take one course for the treatment of of Chinese medicine preparation of the present invention, patient symptom substantially mitigates, and one course for the treatment of of oral traditional Chinese medicine preparation, symptom is substantially good
Turn, of the present invention Chinese medicine preparation one course for the treatment of, clinical cure are administered orally again.
Case 3：Man, 53 years old, before three months, no frequent micturition, urgent urination, odynuria in inducement, with the soreness of waist, weak, shortness of breath, head
Dizzy, edema, become thin, oral one course for the treatment of of Chinese medicine preparation of the present invention, patient symptom substantially mitigates, and one treatment of oral traditional Chinese medicine preparation
Journey, symptom is clearly better, and of the present invention Chinese medicine preparation one course for the treatment of, clinical cure are administered orally again.
It should be pointed out that the specific embodiment more representational example that is the present invention is it is clear that the skill of the present invention
Art scheme is not limited to above-described embodiment, can also have many variations；Those of ordinary skill in the art, clearly public with present invention institute
What what written description that open or according to file was undoubted obtained, all it is considered as this patent scope of the claimed.
Claims (6)
1. a kind of Chinese medicine preparation treating urine urgency-frequency and preparation method it is characterised in that：It is made up of the raw material of following weight portion：
Radix Astragali 300-500 part, fruit of Cherokee rose 170-230 part, Chinese yam 170-230 part, black lotus seed 170-230 part, fructus alpiniae oxyphyllae 170-230 part,
Stir-baked SEMEN ZIZIPHI SPINOSAE 170-230 part, mantis egg-case 50-110 part, Polygonum multiflower knotweed 200-400 part, parasitic loranthus 200-400 part, calcined Dragon's bone 200-400
Part, stamen nelumbini 120-180 part, raspberry 120-180 part, fruit of Chinese wolfberry 120-180 part, Chinese ephedra 10-50 part, calcined oyster shell 300-500 part,
Radix Glycyrrhizae 40-100 part, fructus cannabis 120-180 part, Aspartame 0.001-0.002 part, Sodium Benzoate 0.001-0.002 part.
2. a kind of Chinese medicine preparation treating urine urgency-frequency according to claim 1 preparation method it is characterised in that：Its system
For step it is：
（1）The raw material Radix Astragali, the fruit of Cherokee rose, Chinese yam, stamen nelumbini, raspberry, the fruit of Chinese wolfberry, Chinese ephedra, Radix Glycyrrhizae, fructus cannabis is taken to put into pulverizer powder
Broken, cross 50-60 mesh sieve, obtain raw material powder, standby；
（2）Take raw material black lotus seed, fructus alpiniae oxyphyllae, stir-baked SEMEN ZIZIPHI SPINOSAE, mantis egg-case, Polygonum multiflower knotweed, parasitic loranthus to put into pulverizer to pulverize, cross 60-80
Mesh sieve, obtains raw material powder, standby；
（3）Raw material calcined Dragon's bone, calcined oyster shell is taken to be pulverized with pulverizer, smashing fineness is 100-120 mesh, standby；
（4）By step（1）Gained raw material powder and step（2）Gained raw material powder and step（3）Gained pulverize after calcined Dragon's bone, forge male
Oyster adds water to cook three times, adds the water of the 10-12 times amount of raw material weight for the first time, decocts 0.4-1 hour, pours out liquid, second
Plus the water of raw material weight 6-8 times amount, decoct 0.4-1 hour, pour out liquid, the water of third time plus raw material weight 6-8 times amount, decoct
0.4-1 hour, merges three liquids, filters, and filtrate is concentrated into 55-60 DEG C and surveys the clear cream that relative density is 1.08-1.15, plus
The appropriate amount of ethanol of 90-95%, during 5-10 DEG C of standing 24-48, filters, decompression filtrate recycling ethanol is concentrated into no alcohol taste, filtrate
Survey the thick paste that relative density is 1.25-1.35 for 55-60 DEG C, standby；
（5）Raw material Aspartame, Sodium Benzoate is taken to be dissolved into respectively in water, standby；
（6）By step（4）Gained thick paste adds the pure water of its weight 3-5 times amount, adds the Aspartame after dissolving, benzene first
Sour sodium, to being completely dissolved, with centrifugal filtration, revolution 10000-15000r/min, the time is 5-15s to stirring 5-10min, refrigeration,
Standing 24-48 when, then use centrifugal filtration, revolution 16000-20000r/min, the time be 5-15s, be finally packaged in 20ml bottle
Sealing, with the sterilizing of boiling water high temperature 10-15 minute, cooling, packaging, obtains final product the Chinese medicine preparation for the treatment of urine urgency-frequency.
3. a kind of Chinese medicine preparation treating urine urgency-frequency according to claim 2 preparation method it is characterised in that：Its system
For step it is：
（1）The raw material Radix Astragali, the fruit of Cherokee rose, Chinese yam, stamen nelumbini, raspberry, the fruit of Chinese wolfberry, Chinese ephedra, Radix Glycyrrhizae, fructus cannabis is taken to put into pulverizer powder
Broken, cross 50 mesh sieves, obtain raw material powder, standby；
（2）Take raw material black lotus seed, fructus alpiniae oxyphyllae, stir-baked SEMEN ZIZIPHI SPINOSAE, mantis egg-case, Polygonum multiflower knotweed, parasitic loranthus to put into pulverizer to pulverize, cross 60 mesh
Sieve, obtains raw material powder, standby；
（3）Raw material calcined Dragon's bone, calcined oyster shell is taken to be pulverized with pulverizer, smashing fineness is 100 mesh, standby；
（4）By step（1）Gained raw material powder and step（2）Gained raw material powder and step（3）Gained pulverize after calcined Dragon's bone, forge male
Oyster adds water to cook three times, adds the water of 10 times amount of raw material weight for the first time, decocts 0.8 hour, pours out liquid, second plus raw material
The water of weight 8 times amount, decocts 0.8 hour, pours out liquid, the water of third time plus raw material weight 8 times amount, decocts 0.8 hour, merges
Three liquids, filter, and filtrate is concentrated into 55 DEG C and surveys the clear cream that relative density is 1.08, the appropriate amount of ethanol plus 95%, 8 DEG C of standings 24
When, filter, to no alcohol taste, filtrate is concentrated into 60 DEG C and surveys the thick paste that relative density is 1.25 decompression filtrate recycling ethanol, standby；
（5）Raw material Aspartame, Sodium Benzoate is taken to be dissolved into respectively in water, standby；
（6）By step（4）Gained thick paste adds the pure water of its weight 3 times amount, adds the Aspartame after dissolving, benzoic acid
Sodium, 5min is to being completely dissolved for stirring, and with centrifugal filtration, revolution 10000r/min, the time is 5s, refrigeration, during standing 24, then with from
The heart filters, revolution 16000r/min, and the time is 5s, is finally packaged in sealing in 20ml bottle, with the sterilizing in 15 minutes of boiling water high temperature, cold
But, pack, obtain final product the Chinese medicine preparation for the treatment of urine urgency-frequency.
4. a kind of Chinese medicine preparation treating urine urgency-frequency according to claim 1 it is characterised in that：By following weight portion
Raw material is made：400 parts of the Radix Astragali, 200 parts of the fruit of Cherokee rose, 200 parts of Chinese yam, 200 parts of black lotus seed, 200 parts of fructus alpiniae oxyphyllae, 200 parts of stir-baked SEMEN ZIZIPHI SPINOSAE,
80 parts of mantis egg-case, 300 parts of Polygonum multiflower knotweed, 300 parts of parasitic loranthus, 300 parts of calcined Dragon's bone, 150 parts of stamen nelumbini, 150 parts of raspberry, the fruit of Chinese wolfberry
150 parts, 30 parts of Chinese ephedra, 400 parts of calcined oyster shell, 70 parts of Radix Glycyrrhizae, 150 parts of fructus cannabis, 0.0015 part of Aspartame, Sodium Benzoate
0.0015 part.
5. a kind of Chinese medicine preparation treating urine urgency-frequency according to claim 1 it is characterised in that：By following weight portion
Raw material is made：500 parts of the Radix Astragali, 230 parts of the fruit of Cherokee rose, 230 parts of Chinese yam, 230 parts of black lotus seed, 230 parts of fructus alpiniae oxyphyllae, 230 parts of stir-baked SEMEN ZIZIPHI SPINOSAE,
110 parts of mantis egg-case, 400 parts of Polygonum multiflower knotweed, 400 parts of parasitic loranthus, 400 parts of calcined Dragon's bone, 180 parts of stamen nelumbini, 180 parts of raspberry, the fruit of Chinese wolfberry
180 parts, 50 parts of Chinese ephedra, 500 parts of calcined oyster shell, 100 parts of Radix Glycyrrhizae, 180 parts of fructus cannabis, 0.002 part of Aspartame, Sodium Benzoate
0.002 part.
6. a kind of Chinese medicine preparation treating urine urgency-frequency according to claim 1 it is characterised in that：By following weight portion
Raw material is made：300 parts of the Radix Astragali, 170 parts of the fruit of Cherokee rose, 170 parts of Chinese yam, 170 parts of black lotus seed, 170 parts of fructus alpiniae oxyphyllae, 170 parts of stir-baked SEMEN ZIZIPHI SPINOSAE,
50 parts of mantis egg-case, 200 parts of Polygonum multiflower knotweed, 200 parts of parasitic loranthus, 200 parts of calcined Dragon's bone, 120 parts of stamen nelumbini, 120 parts of raspberry, the fruit of Chinese wolfberry
120 parts, 10 parts of Chinese ephedra, 300 parts of calcined oyster shell, 40 parts of Radix Glycyrrhizae, 120 parts of fructus cannabis, 0.001 part of Aspartame, Sodium Benzoate 0.001
Part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610992111.4A CN106389992A (en) | 2016-11-11 | 2016-11-11 | Traditional Chinese medicine preparation for treating frequent micturition and urgent micturition and preparation method of traditional Chinese medicine preparation for treating frequent micturition and urgent micturition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610992111.4A CN106389992A (en) | 2016-11-11 | 2016-11-11 | Traditional Chinese medicine preparation for treating frequent micturition and urgent micturition and preparation method of traditional Chinese medicine preparation for treating frequent micturition and urgent micturition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106389992A true CN106389992A (en) | 2017-02-15 |
Family
ID=59229962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610992111.4A Pending CN106389992A (en) | 2016-11-11 | 2016-11-11 | Traditional Chinese medicine preparation for treating frequent micturition and urgent micturition and preparation method of traditional Chinese medicine preparation for treating frequent micturition and urgent micturition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106389992A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735972A (en) * | 2013-12-27 | 2014-04-23 | 苏海燕 | Medicine for treating senile urinary incontinence and preparation method thereof |
-
2016
- 2016-11-11 CN CN201610992111.4A patent/CN106389992A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103735972A (en) * | 2013-12-27 | 2014-04-23 | 苏海燕 | Medicine for treating senile urinary incontinence and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103349753B (en) | Traditional Chinese medicine composition for treating kidney deficiency | |
| CN108014289A (en) | For nursing one's health the Chinese herbal ointment formula and its processing method of yang-deficiency constitution | |
| CN103316284A (en) | Cholelithiasis treatment drug | |
| CN101879288A (en) | Chinese medicinal formula for treating hydronephrosis | |
| CN104740437A (en) | Traditional Chinese medicine composition for treating constipation and preparation method of traditional Chinese medicine composition | |
| CN103191347A (en) | Traditional Chinese medicine composition for treating gynecological inflammation | |
| CN105878574B (en) | It is a kind of to treat Chinese medicine composition of kidney deficiency and preparation method thereof | |
| CN106421585A (en) | Traditional Chinese medicine composition for treating kidney deficiency and preparation method | |
| CN103656365A (en) | Traditional Chinese medicine for treating heart and liver yin deficiency syndrome type hyperthyroidism | |
| CN103071076A (en) | Traditional Chinese medicament composition for promoting recovery after cesarean section by lavipeditum nursing and application | |
| CN103191303B (en) | Traditional Chinese medicine for treating night sweat | |
| CN106389992A (en) | Traditional Chinese medicine preparation for treating frequent micturition and urgent micturition and preparation method of traditional Chinese medicine preparation for treating frequent micturition and urgent micturition | |
| CN102935214B (en) | Traditional Chinese medicinal composition for treating uremia | |
| CN105267630A (en) | Traditional Chinese medicine for treating tinnitus | |
| CN105497738A (en) | Gastroptosis treating traditional Chinese medicine composition | |
| CN104474125A (en) | Oral traditional Chinese medicine liquor for treating Sheehan's syndrome and preparation method of oral traditional Chinese medicine liquor | |
| CN103301334B (en) | Traditional Chinese medicine for treating children cough | |
| CN108272999A (en) | A kind of Chinese medicine and preparation method thereof for treating impotence | |
| CN103623287B (en) | A kind ofly treat Chinese medicine lotion of vaginitis and cervical erosion and preparation method thereof | |
| CN107158157A (en) | A kind of pill medicine treated under women's kidney deficiency cold-dampness type band and preparation method thereof | |
| CN102988630A (en) | Pharmaceutical composition for treating gout disease, and preparation method thereof | |
| CN101869629B (en) | Traditional Chinese medicine for treating renal calculus | |
| CN105497546A (en) | Traditional Chinese medicine composition for treating internal hemorrhoids and preparation method | |
| CN104258200A (en) | Traditional Chinese medicine for treating constipation and preparation method thereof | |
| CN107260960A (en) | A kind of forgetful Chinese medicine composition treated caused by kidney deficiency and liver and deficiency of qi and blood |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170215 |