CN106389917A - Traditional Chinese medicine composition for skin ulcer, and preparation method thereof - Google Patents
Traditional Chinese medicine composition for skin ulcer, and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a traditional Chinese medicine composition for skin ulcer in the field of a traditional Chinese medicine preparation. The traditional Chinese medicine composition is prepared from the following ingredients in proportion by weight: 20 to 30g of fresh rhizoma bletillae, 15 to 25g of bamboo leaves, 35 to 45g of raw gypsum, 10 to 20g of rhizoma coptidis, 10 to 20g of indigo naturalis, 20 to 30g of cuttlebone and 3 to 6g of amoxicillin. The medicine composition provided by the invention has the advantages that all medicine is matched; necrotic tissues or foreign matters in the wound can be thoroughly cleared away; the deep clean and bacteriostasis effects are achieved on the skin healing environment; the skin regenerating tissue growth is promoted; the self-healing effect of the skin is accelerated and enhanced; the beneficial effects of quick medical efficacy and long-time recurrence prevention capability are achieved.
Description
Technical field
The present invention relates to field of traditional Chinese is and in particular to a kind of Chinese medicine composition for skin ulcer and its preparation side
Method.
Background technology
Ulcer be skin or mucous membrane surface tissue limit office property defect, fester, its surface is often coated with puss, slough
Or crust.Ulcer is a kind of frequently-occurring disease, commonly encountered diseases, typically can not effect a radical cure.
The reason cause skin ulcer mainly has：First, treatment of wounds is improper.As inadequate drainage, dressing mistake, do not have in time
And thoroughly remove slough or foreign body in wound etc.；2nd, blood fortune in local is bad.Inside 1/3 under shank, soft tissue is few, blood
Fortune is poor, and healing ability is weak, skin ulcer, does not often only heal long, easily forms Chronic leg ulcer；3rd, local specific infection；
4th, malignant tumor；5th, neural malnutrition.
Treat the medicine of skin ulcer, either Chinese medicine composition or Western medicine, on the one hand, the stimulation all to skin at present
Property strong, carry on the skin of ulcer in script, the pain of skin can be increased；On the other hand, the medicine of existing treatment skin ulcer
Thing can only be of short duration play therapeutic effect, the cycle is short of recurrence, will recur within usual 2～3 months, the therapeutic effect therefore reaching
Not good.
Content of the invention
The present invention is directed to above-mentioned technical problem, provides one kind to be used for skin ulcer, and controls difficulty in relapse after healing
Chinese medicine composition.
In order to solve above-mentioned technical problem, the present invention provides following technical scheme：A kind of Chinese medicine group for skin ulcer
Compound, including component and component consumption be fresh Pseudobulbus Bletillae (Rhizoma Bletillae) 20～30g, Folium Bambusae 15～25g, Gypsum Fibrosum 35～45g, Rhizoma Coptidis 10～
20g, Indigo Naturaliss 10～20g, Endoconcha Sepiae 20～30g, amoxicillin 3～6g.
Add Pseudobulbus Bletillae (Rhizoma Bletillae) in this programme, the skin at ulcer is reached with convergence, the effect of hemostasis, promotes the life of skin histology
Long, contribute to skin healing；It is equipped with the Endoconcha Sepiae with the effect of removing dampness sore again, the skin at ulcer is reached with dehumidifying, suppression
The effect suppurated, and then strengthen Pseudobulbus Bletillae (Rhizoma Bletillae) convergence, the effect of granulation promoting.Add Rhizoma Coptidis, Folium Bambusae and Gypsum Fibrosum, three's cooperation has preferably
Heat clearing away, Detoxication, to having fungistatic effect at ulcer, the cooperation of Rhizoma Coptidis, Folium Bambusae and Gypsum Fibrosum three can promote Pseudobulbus Bletillae (Rhizoma Bletillae) and
The performance of effect of Endoconcha Sepiae, strengthens the effect of Pseudobulbus Bletillae (Rhizoma Bletillae) and Endoconcha Sepiae healing skin.It is equipped with and there is removing heat from blood, the green grass or young crops of pathogenic fire purging effect
Black pigment used by women in ancient times to paint their eyebrows, promotes the heat clearing and damp drying of Rhizoma Coptidis, effect of eliminating fire and detoxication, and then makes Rhizoma Coptidis, Indigo Naturaliss and Endoconcha Sepiae three cooperation lifting dampness
And bacteriostasis efficacy, promote the healing of ulcer.Folium Bambusae, Gypsum Fibrosum cooperation have functions that clearing away heat to alleviate pain, blood cooling and ecchymoses removing, using this
During Chinese medicine composition, mitigate the zest of pharmaceutical through skin, weaken the pain of skin, also there is promotion skin histology life simultaneously
Long, accelerate the effect of granulation promoting.This programme is finally also added into amoxicillin, mainly uses its cooperation Rhizoma Coptidis, Folium Bambusae and calculogenesis
Cream, strengthens bacteria growing inhibiting, and for the benefit of the environment of skin healing provides safeguard, and then promotes the effect of wound healing, effectively
Prevention subinfection again.
This programme Chinese medicine composition, all medicine cooperations, with the thorough slough removed in wound or foreign body, to skin healing
Environment reach deep clean, antibacterial effect, increase the growth of skin revitalization tissue, accelerate, strengthen the spontaneous recovery effect of skin,
There is the beneficial effect that fast, the permanent prevention of drug effect is recurred again.
Further, as the prioritization scheme one to base case, the present invention is used for the Chinese medicine composition of skin ulcer, including
Component and component consumption be fresh Pseudobulbus Bletillae (Rhizoma Bletillae) 30g, Folium Bambusae 20g, Gypsum Fibrosum 45g, Rhizoma Coptidis 10g, Indigo Naturaliss 15g, Endoconcha Sepiae 25g, Ah
Amdinocillin 3g.In this programme the consumption of Pseudobulbus Bletillae (Rhizoma Bletillae) and Gypsum Fibrosum relatively many it is adaptable to the skin that causes of ulcer seriously rotten to the corn hence it is evident that
Bleeding the skin ulcer of phenomenon occur, removing dampness, hemostasis, removing pathogenic heat from blood and toxic substance from the body effect strong, accelerate the healing of erosion skin.
Further, as the prioritization scheme two to base case, the present invention is used for the Chinese medicine composition of skin ulcer, including
Component and component consumption be fresh Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Folium Bambusae 25g, Gypsum Fibrosum 35g, Rhizoma Coptidis 15g, Indigo Naturaliss 10g, Endoconcha Sepiae 30g, Ah
Amdinocillin 6g.The consumption of this programme Folium Bambusae and Endoconcha Sepiae is relatively many it is adaptable to ulcer is also with the skin of abscess, heat clearing away, disappears
Skin ulcer, evacuation of pus effect all good, and then promote puss discharge, accelerate wound healing.
Further, as the prioritization scheme three to base case, the present invention is used for the Chinese medicine composition of skin ulcer, including
Component and component consumption be fresh Pseudobulbus Bletillae (Rhizoma Bletillae) 25g, Folium Bambusae 15g, Gypsum Fibrosum 40g, Rhizoma Coptidis 20g, Indigo Naturaliss 20g, Endoconcha Sepiae 20g, Ah
Amdinocillin 5g.The consumption of this programme Gypsum Fibrosum and fresh Pseudobulbus Bletillae (Rhizoma Bletillae) is greatly it is adaptable to ulcer is with skin ulceration, and the feelings of sharp ache
Condition, strengthens the effect of removing heat from blood analgesic.
Further, as the further optimization to each scheme above, the present invention is used for the Chinese medicine composition of skin ulcer
Component also include Herba Lobeliae Chinensis 10～20g.After adding Herba Lobeliae Chinensis, may also suppress the growth of mycete, strengthen suppression pathogen growth
Effect.Increased this Chinese medicine composition and the impetigo around the lip of oral cavity is reached with therapeutical effect, accelerate skin at impetigo
Healing.
In order that each component can efficiently utilize in this programme, the waste of less effective ingredient, strengthen each drug component
Amalgamation, present invention also offers this is used for the preparation method of the Chinese medicine composition of skin ulcer, comprise the following steps：
Step one, weigh each component according to quantity, standby；The mixing of Folium Bambusae, Rhizoma Coptidis, Gypsum Fibrosum and Endoconcha Sepiae is put in container, adds
400～600g clear water, after decocting 60～80min, filters to take decoction liquor；
Step 2, fresh Pseudobulbus Bletillae (Rhizoma Bletillae) is smashed taking juice, juice is mixed with decoction liquor, after adding Indigo Naturaliss, stir, boil 8～
12min becomes sticky paste, prepared Traditional Chinese drug mixture；
Step 3, in the Traditional Chinese drug mixture of step 2 add amoxicillin, stir.
Folium Bambusae, Rhizoma Coptidis, Gypsum Fibrosum and Endoconcha Sepiae are decocted by this method, because the matter of Rhizoma Coptidis, Gypsum Fibrosum and Endoconcha Sepiae
Ground is comparatively dense, and by decocting, clear water penetrates into the inside of medicine, beneficial to by effective ingredient dissolution, and if Folium Bambusae passes through squeezing,
Then juice is few, is used together using the slag after usually requiring that and squeezing, such method is unsuitable for skin ulcer, can increase on the contrary
The sense of discomfort of Cortex Acanthopanacis Radicis skin, so extract its effective ingredient by decocting.It is primarily due to white after relatively dry using fresh Pseudobulbus Bletillae (Rhizoma Bletillae)
And for, the better efficacy of fresh Pseudobulbus Bletillae (Rhizoma Bletillae), by smashing squeeze juice, then coordinate the Indigo Naturaliss of script powder and decoct well-done medicine
Liquid, after being brewed into cream, the pro-skin function well of the Chinese medicine composition being finally obtained, be conducive to the contact that medicine is with wound, and then
Promote medicine to play effect, be eventually adding the amoxicillin of finished product, the comprehensive utilization rate improving each effective ingredient.
Specific embodiment
With reference to embodiment, technical solution of the present invention is further illustrated：
Embodiment 1：
A kind of Chinese medicine composition for skin ulcer it is characterised in that：Including component and component consumption be fresh Pseudobulbus Bletillae (Rhizoma Bletillae)
30g, Folium Bambusae 20g, Gypsum Fibrosum 45g, Rhizoma Coptidis 10g, Indigo Naturaliss 15g, Endoconcha Sepiae 25g, amoxicillin 3g, Herba Lobeliae Chinensis 15g.
Embodiment 2：
A kind of Chinese medicine composition for skin ulcer it is characterised in that：Including component and component consumption be fresh Pseudobulbus Bletillae (Rhizoma Bletillae)
20g, Folium Bambusae 25g, Gypsum Fibrosum 35g, Rhizoma Coptidis 15g, Indigo Naturaliss 10g, Endoconcha Sepiae 30g, amoxicillin 6g, Herba Lobeliae Chinensis 20g.
Embodiment 3：
A kind of Chinese medicine composition for skin ulcer it is characterised in that：Including component and component consumption be fresh Pseudobulbus Bletillae (Rhizoma Bletillae)
25g, Folium Bambusae 15g, Gypsum Fibrosum 40g, Rhizoma Coptidis 20g, Indigo Naturaliss 20g, Endoconcha Sepiae 20g, amoxicillin 5g, Herba Lobeliae Chinensis 10g.
Embodiment 4：
Taking embodiment 1 as a example, the preparation method of Chinese medicine composition for skin ulcer a kind of to the present invention, say in detailed below
Bright, it comprises the following steps：
Step one, weigh fresh Pseudobulbus Bletillae (Rhizoma Bletillae) 30g, Folium Bambusae 20g, Gypsum Fibrosum 45g, Rhizoma Coptidis 10g, Indigo Naturaliss 15g, Endoconcha Sepiae 25g, amoxicillin
3g, Herba Lobeliae Chinensis 15g, standby；Appearance is put in the mixing of 20g Folium Bambusae, 10g Rhizoma Coptidis, 45g Gypsum Fibrosum, 25g Endoconcha Sepiae and 15g Herba Lobeliae Chinensis
In device, add 400～600g（The preferred 500g of this programme）Clear water, decocts 60～80min（The preferred 60min of this programme）Afterwards, filter
Take decoction liquor；
Step 2, fresh for 30g Pseudobulbus Bletillae (Rhizoma Bletillae) is smashed taking juice, juice is mixed with decoction liquor, after adding 15g Indigo Naturaliss, stir, endure
System 8～12min becomes sticky paste, prepared Traditional Chinese drug mixture；
Step 3, in the Traditional Chinese drug mixture of step 2 add 3g amoxicillin, stir.
Comparative example 1：BINGPENG SAN.
Comparative example 2：Gold as one wishes dissipates.
Test：
It is usually used in the BINGPENG SAN for the treatment of ulcer using the Chinese medicine composition and market of present invention preparation and gold as one wishes dissipates, to hospital
The skin ulcer randomly drawed, with the patient of suppuration phenomenon, divides 5 groups, every group of 3 people, and every group respectively using in embodiment 1～3
Drug composition, BINGPENG SAN and gold as one wishes dissipate, and the pain that record patient uses is cured the cycle by with average, and average recurrence
In the cycle, the results are shown in Table 1.
Table 1：
Can draw, using traditional Chinese medicine composition for treating skin ulcer of the present invention, during use, there is refrigerant sense by above-mentioned table 1, and right
The zest of wound is weaker, and therefore the sensation of pain is slight, and BINGPENG SAN and gold as one wishes dissipate and all shows as no refrigerant sense, pain
Acutely.Relatively BINGPENG SAN and gold as one wishes dissipate, and the curative effect of Chinese medicine composition of the present invention is fast, and recur again after being placed in interval when
Between long, there is more preferable treatment and the effect of Control in recurring to skin ulcer.
For a person skilled in the art, on the premise of without departing from present configuration, some changes can also be made
Shape and improvement, these also should be considered as protection scope of the present invention, and these are all without the effect affecting present invention enforcement and patent
Practicality.
Claims (6)
1. a kind of Chinese medicine composition for skin ulcer it is characterised in that:Including component and component consumption be fresh Pseudobulbus Bletillae (Rhizoma Bletillae)
20～30g, Folium Bambusae 15～25g, Gypsum Fibrosum 35～45g, Rhizoma Coptidis 10～20g, Indigo Naturaliss 10～20g, Endoconcha Sepiae 20～30g, A Mo
XiLin 3～6g.
2. as claimed in claim 1 a kind of Chinese medicine composition for skin ulcer it is characterised in that：Including component and group
The consumption dividing is fresh Pseudobulbus Bletillae (Rhizoma Bletillae) 30g, Folium Bambusae 20g, Gypsum Fibrosum 45g, Rhizoma Coptidis 10g, Indigo Naturaliss 15g, Endoconcha Sepiae 25g, amoxicillin 3g.
3. as claimed in claim 1 a kind of Chinese medicine composition for skin ulcer it is characterised in that：Including component and group
The consumption dividing is fresh Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Folium Bambusae 25g, Gypsum Fibrosum 35g, Rhizoma Coptidis 15g, Indigo Naturaliss 10g, Endoconcha Sepiae 30g, amoxicillin 6g.
4. as claimed in claim 1 a kind of Chinese medicine composition for skin ulcer it is characterised in that：Including component and group
The consumption dividing is fresh Pseudobulbus Bletillae (Rhizoma Bletillae) 25g, Folium Bambusae 15g, Gypsum Fibrosum 40g, Rhizoma Coptidis 20g, Indigo Naturaliss 20g, Endoconcha Sepiae 20g, amoxicillin 5g.
5. a kind of Chinese medicine composition for skin ulcer as any one of Claims 1-4 it is characterised in that：Its
Component also includes Herba Lobeliae Chinensis 10～20g.
6. a kind of Chinese medicine composition preparation method for skin ulcer as any one of Claims 1-4, its feature
It is：Comprise the following steps：
Step one, weigh each component according to quantity, standby；The mixing of Folium Bambusae, Rhizoma Coptidis, Gypsum Fibrosum and Endoconcha Sepiae is put in container, adds
400～600g clear water, after decocting 60～80min, filters to take decoction liquor；
Step 2, fresh Pseudobulbus Bletillae (Rhizoma Bletillae) is smashed taking juice, juice is mixed with decoction liquor, after adding Indigo Naturaliss, stir, boil 8～
12min becomes sticky paste, prepared Traditional Chinese drug mixture；
Step 3, in the Traditional Chinese drug mixture of step 2 add amoxicillin, stir.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611008878.5A CN106389917A (en) | 2016-11-16 | 2016-11-16 | Traditional Chinese medicine composition for skin ulcer, and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611008878.5A CN106389917A (en) | 2016-11-16 | 2016-11-16 | Traditional Chinese medicine composition for skin ulcer, and preparation method thereof |
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| CN106389917A true CN106389917A (en) | 2017-02-15 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1129132A (en) * | 1995-12-14 | 1996-08-21 | 王利亚 | Ulceromembrane of Chinese medicine and production technology thereof |
| CN102688383A (en) * | 2011-12-21 | 2012-09-26 | 河南科技大学 | Traditional Chinese medicine composite for treating body surface ulcer or fester |
| CN103055141A (en) * | 2011-10-19 | 2013-04-24 | 徐庆军 | Drug for treatment of gastric ulcer |
-
2016
- 2016-11-16 CN CN201611008878.5A patent/CN106389917A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1129132A (en) * | 1995-12-14 | 1996-08-21 | 王利亚 | Ulceromembrane of Chinese medicine and production technology thereof |
| CN103055141A (en) * | 2011-10-19 | 2013-04-24 | 徐庆军 | Drug for treatment of gastric ulcer |
| CN102688383A (en) * | 2011-12-21 | 2012-09-26 | 河南科技大学 | Traditional Chinese medicine composite for treating body surface ulcer or fester |
Non-Patent Citations (1)
| Title |
|---|
| 罗森亮等: "愈疡膏治疗静脉性小腿溃疡46例观察", 《实用中医药杂志》 * |
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Application publication date: 20170215 |
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