CN106389806A - Radix angelicae sinensis containing health care medicine for preventing and treating pneumoconiosis - Google Patents

Radix angelicae sinensis containing health care medicine for preventing and treating pneumoconiosis Download PDF

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Publication number
CN106389806A
CN106389806A CN201511013259.0A CN201511013259A CN106389806A CN 106389806 A CN106389806 A CN 106389806A CN 201511013259 A CN201511013259 A CN 201511013259A CN 106389806 A CN106389806 A CN 106389806A
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angelicae sinensis
radix angelicae
preventing
grams
raw material
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张文举
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Dingxi Huaqingyuan Engineering Research And Development Center Of Traditional Chinese Medicine
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Dingxi Huaqingyuan Engineering Research And Development Center Of Traditional Chinese Medicine
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/062Ascomycota
    • A61K36/066Clavicipitaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • General Health & Medical Sciences (AREA)
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Abstract

The invention provides a radix angelicae sinensis containing health care medicine for preventing and treating pneumoconiosis. The health care medicine mainly consists of the following raw materials: radix angelicae sinensis, radix scutellariae, spica prunellae, bulbus fritillariae cirrhosae, isaria cicadae miquel and trichosanthes peel. The health care medicine provided by the invention conforms to the principle of clearing lung and removing calculus and is assisted by effects of tonifying qi and nourishing yin, softening hard mass and reducing phlegm, removing stasis and dredging collaterals, and the health care medicine has a function of preventing the pneumoconiosis.

Description

A kind of health medicine of the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis
Technical field
The invention belongs to health products, the health medicine of particularly a kind of preventing and treating pneumoconiosis containing Radix Angelicae Sinensis.
Background technology
Pneumoconiosis or pneumoconiosis, also known as black lung disease, Hong Kong claims pneumoconiosis, China's Mainland and Taiwan to be commonly called as silicosis Disease, also known as pneumoconiosis, sand lung, is a kind of pulmonary fibrotic disease.Patient is generally chronically at dust-laden place, big because sucking Amount dust, leads to the alveolar under tip bronchus to accumulate dust, after a period of time, intrapulmonary changes, and forms fibrillatable stove.Silicon Lung disease is mainly human body and sucks caused by the dust of silicon metal, the main component of silicon metal mainly have soil, sand, granites and Other rock compositions.The cardinal symptom of silicosis is:Short of breath, fever, tired, no appetite, pectoralgia, dry cough, breathing decline, After be possible to lethal.Pathogenesis:Silica grit, or it is silicious dust, swallowed by pulmonary macrophage after sucking alveolar, i.e. dirt Cell, the phagosome containing silicious dust is merged with lysosome becomes secondary lysosome.Silica on Peritoneal Macrophages has obvious poison Property effect, the hydroxyl of quartz surfaces and the phosphatide of lysosome membrane or albumen form hydrogen bond, lead to phagocyte lysosome to be disintegrated, Cell membrane itself is also destroyed afterwards, and silicious dust disengages, and afterwards again by other macrophage phagocytics, is so repeated.Impaired or broken Bad macrophage release " fibrogenic factor ", and activate fibroblast, lead to collagen fiber hyperplasia.Macrophage is disintegrated When released antigen, i.e. silica, immune stimulating activity cell, produce antibody, antigen-antibody reaction produces compound and complement Together, form hyaline substance to be deposited on collagenous fibres, make the connective tissue transparent sample outward appearance newly being formed.In silicon tubercle In evolution, there is more thick liquid cell about.Silicon tubercle is the characteristic lesions of silicosis, and the gathering of dust cell is silicon tubercle The basis being formed.After dust cell group is formed, there is the appearance of fibroblast proliferation and reticular fibre about.The latter increases thick Become collagenous fibres with denaturation, eventually form collagen tubercle, hyalinization in its central authorities.
Pulmonary fibrosis general terms are it is simply that played many " calluses " on alveolar or between alveolar.Play callus, The elasticity of its alveolar, systolic and diastolic function decline or diffusion reduces, the respiratory function of this lung to be affected that is bound to.Respiratory function subtracts Low, affect blood oxygen function of exchange.Ming Dynasty Zhao Xianke is his《Thorough Knowledge of Medicine》" lid lung is empty clearly mansion, and a thing is not allowed, hair for middle theory Must cough, and lung being a delicate viscus, fear hot chilly." this doctor by this characteristic of lung say fully aware of clearly.Enter the dirt of alveolar Grain only has very small part by dust cell, i.e. phagocytosis has the phagocyte of dust, brings alveolar septum into, through lymph or blood circulation And reach its hetero-organization of lung and human body, cause physiological and pathological to act on.The pathology that silicosis easily causes includes lung cancer, bronchus Inflammation, chronic obstructive lung pathology, pulmonary tuberculosis, chorionitis, even can cause renal lesions.
Lung fibrosis are summarized its etiology and pathogenesis by traditional Chinese medicine:Inadequate natural endowment, natural endowment is weak, and the positive deficiency of vital energy declines, and that is, lung kidney qi is cloudy Two is empty, and multiple because of exopathogen criminal's lung, inside and outside conjunction is evil, hinders Tianjin gas consumption, the withered consumptive lung disease in Tianjin, with the passing of time leads to lung spleen kidney three dirty all empty and is formed.Its With nourishing lung and kidney, dissolving stasis resolving sputum as basic therapy.Because silica dust belongs to the dry strong heresy of metal and stone, and lung is the dirty of preferring moisture to dryness, silica dust Deposition is condensed in lung, can be strongly fragrant and change heat, and scorching refining Tianjin is phlegm, and phlegm stops up the stagnation of the circulation of vital energy, hematogenous blockage, then hemostasis stupid phlegm knot, blocks lung Key, causes lung qi obstruction the lung such as cough, syndrome characterized by dyspnea shortness of breath, cough up phlegm and hindering symptom;If protracted inflammation is with the passing of time, scorching, phlegm-blood stasis must consume Impairment of qi is cloudy, leads to the cloudy all wounds of lungs gas, even can affect other organs.Therefore it is directed to pneumoconiosis initial stage patient, therapy is arranged with clearing lung-heat Stone is principle, and often assistant is with supplementing qi and nourishing yin, softening and eliminating sputum, eliminating blood stasis and smoothing collaterals.
Content of the invention
It is an object of the invention to provide one kind is with clearing lung-heat row's stone as principle, assistant is led to supplementing qi and nourishing yin, softening and eliminating sputum, dissolving stasis The health medicine of the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis of network.
The technical scheme is that:
A kind of health medicine, raw material and the weight ratio of the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis:Radix Angelicae Sinensis 10 ~ 25%, the root of large-flowered skullcap 10 ~ 25%, the summer Withered grass 10 ~ 28%, golden cicada spends 10 ~ 25%, Bulbus Fritillariae Cirrhosae 10 ~ 28%, and each raw material is respectively prepared no less than 80 mesh PERICARPIUM TRICHOSANTHIS 10 ~ 20% Powdery, be pressed into tablet package after mixing.
As a kind of preferred version, each raw material is respectively prepared the powdery no less than 80 mesh, mixes, add mixture After the drinking water that 1.5 ~ 2.5 times of weight boils 20 ~ 35 minutes, pack.
As a kind of preferred version, each raw material organic extractant solution method is respectively prepared extract, mixes, system Become oral liquid to pack.
As a kind of preferred version, each raw material is respectively prepared the powdery no less than 80 mesh, mixes, be divided into parcel, Make fast tea bag packaging.
Primary raw material of the present invention is Radix Angelicae Sinensis, the root of large-flowered skullcap, selfheal, Bulbus Fritillariae Cirrhosae, and golden cicada is spent, PERICARPIUM TRICHOSANTHIS.Effect of each raw material is such as Under.
The effect of Radix Angelicae Sinensis and effect:Motherland's medical science thinks, Radix Angelicae Sinensis is sweet and weighs, therefore specially can enrich blood, and its gas is light and pungent, therefore again Energy promoting circulation of blood, bowl spares has, has benefit, be the key medicine in blood in row.Thus, it can be enriched blood, and can invigorate blood circulation, and both can stimulate the menstrual flow, and energy Active.
The effect of the root of large-flowered skullcap and effect:Cure mainly heat-clearing and damp-drying drug, purging intense heat and detonicating, stop blooding, antiabortive, hypotensive, for damp-warm syndrome, heat temperature Evil of vomitting uncomfortable in chest, damp and hot feeling of fullness, rush down dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus.
The effect of selfheal and effect:Softening and resolving hard mass, controls scrofula and goes through tuberculosis.
The effect of PERICARPIUM TRICHOSANTHIS and effect:Nature and flavor are sweet, tremble with fear.Enter lung, stomach.Moistening lung for removing phlegm, sharp gas width chest.Control phlegm-heat cough, Pharyngalgia, pectoralgia, spit blood, bleeding from five sense organs or subcutaneous tissue, quench one's thirst, constipation, ulcerative carbuncle pyogenic infections.
①《Book on Chinese herbal medicine is just read》:" clearing lung-heat.”
②《Records of Tradition Chinese and Western Medicine in Combination》:" clearing lung-heat, astringes the lung, relieving coughing, Dingchuan.”
③《Medicine materical crude slice is newly joined》:" the wide obstruction of qi in the chest, changes hot phlegm, promoting production of body fluid and nourishing the lung.”
④《Chinese medicine shape sex experience differential method》:Moistening lung, only quenches one's thirst, sore of subsiding a swelling.
The effect of Bulbus Fritillariae Cirrhosae and effect:It is the rare traditional Chinese medicine moistening the lung and relieve the cough, applicating history is long, and curative effect is distinguished, be renown far and wide At home and abroad.Because Bulbus Fritillariae Cirrhosae not only has good relieving cough and reducing sputum effect, and can support lung yin, a surname lung, moistening lung and clearing lung-heat is hot, be one Taste treats the good medicine of chronic cough asthma due to excessive phlegm, therefore, in the prescription of the illnesss such as many treatment acute tracheitis, bronchitis, pulmonary tuberculosis There is tendril-leaved fritillary bulb in agent or Chinese patent medicine preparation.
The effect of golden cicada flower and effect:Fill blood, beneficial lung kidney, cough-relieving is coughed.Longhua hospital of Shanghai Univ. of Traditional Chinese Medicine, in kidney Have been surprisingly found that in disease, golden cicada is spent flat to raising function of human body, strengthening kidney toxin expelling, purification blood toxicity accumulation, regulation metabolism Scale has good effects.Golden cicada flower is by the toxin absorption such as blocking-up intestines and stomach, absorption blood vivotoxin, purified blood liquid liquid The impaired vital organs of the human body of environment, reparation human body, reconstruction five links of metabolic balance, are conducive to person in middle and old age's chronic disease such as glycosuria The rehabilitation of the diseases such as disease, hypertension, hyperlipidemia, cardiovascular and cerebrovascular disease, insomnia, constipation, osteoporosis, tumour;Due to purifying Blood, cell carries out metabolism in clean blood environment, vivo environment.
The effect medical knowledge of the present invention is:1. vital energy regualting and blood circulation-promoting promotes pulmonary microcirculation, suppresses glandular secretion, reduces sputum life Become, promote the histiocytic reply of pulmonary lesion and power of regeneration.2. cytothesis, improves alveolar physiological function, updates comprehensively Pneumonocyte, strengthens the ventilation capacity of PFT, so that the state of an illness is recovered.3. dredge the channels, removing blood stasis for promoting tissue regeneration, recuperating qi-blood, to disease Sick one outlet.Having induces sweat expels the heat-evil, dredging the channel, detoxicating, relieving inflammation, the effect of adjustment lung or even whole body internal organs qi and blood function. 4. play channels sootheing and network vessel quickening, invigorating the spleen righting, make the transportation capabilities of spleen normal, element culturing fixed folder, so that the airway dysfunction of receiving of kidney is recovered, solution Resolution, liver, kidney, lung, the excessively empty of spleen cross case of a physically strong patient running a high fever shape, reach the equilibrium between yin and yang relation of gentle the five internal organs.
Specific embodiment
Embodiment one:
Take 100 grams of Radix Angelicae Sinensis, 100 grams of the root of large-flowered skullcap, 280 grams of selfheal, golden cicada spends 140 grams, 280 grams of Bulbus Fritillariae Cirrhosae, 100 grams of PERICARPIUM TRICHOSANTHIS, will Each raw material is respectively prepared the powdery of 80 mesh, be pressed into after mixing tablet package containing Radix Angelicae Sinensis preventing and treating pneumoconiosis guarantor Strong medicine.
Embodiment two:
Take 250 grams of Radix Angelicae Sinensis, 250 grams of the root of large-flowered skullcap, 200 grams of selfheal, golden cicada spends 100 grams, 100 grams of Bulbus Fritillariae Cirrhosae, 100 grams of PERICARPIUM TRICHOSANTHIS, will Each raw material is respectively prepared the powdery of 100 mesh, be pressed into after mixing tablet package the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis Health medicine.
Embodiment three:
Take 150 grams of Radix Angelicae Sinensis, 150 grams of the root of large-flowered skullcap, 100 grams of selfheal, golden cicada spends 250 grams, 150 grams of Bulbus Fritillariae Cirrhosae, 200 grams of PERICARPIUM TRICHOSANTHIS, will Each raw material is respectively prepared the powdery of 180 mesh, be pressed into after mixing tablet package the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis Health medicine.
Example IV:
Take 150 grams of Radix Angelicae Sinensis, 150 grams of the root of large-flowered skullcap, 100 grams of selfheal, golden cicada spends 250 grams, 150 grams of Bulbus Fritillariae Cirrhosae, 200 grams of PERICARPIUM TRICHOSANTHIS, will Each raw material is respectively prepared the powdery of 80 mesh, mixes, and adds after 1500 grams of drinking water boil 20 minutes, pack contain There is the health medicine of the preventing and treating pneumoconiosis of Radix Angelicae Sinensis.
Embodiment five:
Take 170 grams of Radix Angelicae Sinensis, 180 grams of the root of large-flowered skullcap, 150 grams of selfheal, golden cicada spends 150 grams, 200 grams of Bulbus Fritillariae Cirrhosae, 150 grams of PERICARPIUM TRICHOSANTHIS, will Each raw material is respectively prepared the powdery of 180 mesh, mixes, after adding 2500 grams of drinking water to boil 35 minutes, pack The health medicine of the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis.
Embodiment six:
Take 200 grams of Radix Angelicae Sinensis, 200 grams of the root of large-flowered skullcap, 240 grams of selfheal, golden cicada spends 120 grams, 120 grams of Bulbus Fritillariae Cirrhosae, 120 grams of PERICARPIUM TRICHOSANTHIS, will Each raw material is respectively prepared the powdery of 120 mesh, mixes, after adding 2000 grams of drinking water to boil 30 minutes, pack The health medicine of the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis.
Embodiment seven:
Take 170 grams of Radix Angelicae Sinensis, 180 grams of the root of large-flowered skullcap, 150 grams of selfheal, golden cicada spends 150 grams, 200 grams of Bulbus Fritillariae Cirrhosae, 150 grams of PERICARPIUM TRICHOSANTHIS, will Each raw material organic extractant solution method is respectively prepared extract, mixes, make oral liquid pack containing work as The health medicine of the preventing and treating pneumoconiosis returned.
Embodiment eight:
Take 150 grams of Radix Angelicae Sinensis, 150 grams of the root of large-flowered skullcap, 100 grams of selfheal, golden cicada spends 250 grams, 150 grams of Bulbus Fritillariae Cirrhosae, 200 grams of PERICARPIUM TRICHOSANTHIS, will Each raw material is respectively prepared the powdery of 80 mesh, mixes, and is divided into parcel, make fast tea bag packaging the preventing and treating containing Radix Angelicae Sinensis The health medicine of pneumoconiosis.

Claims (4)

1. a kind of health medicine, raw material and the weight ratio of the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis:Radix Angelicae Sinensis 10 ~ 25%, the root of large-flowered skullcap 10 ~ 25%, Selfheal 10 ~ 28%, golden cicada spends 10 ~ 25%, Bulbus Fritillariae Cirrhosae 10 ~ 28%, and each raw material is respectively prepared no less than 80 PERICARPIUM TRICHOSANTHIS 10 ~ 20% Purpose powdery, is pressed into tablet package after mixing.
2. the health medicine of the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis as claimed in claim 1, each raw material is respectively prepared and is no less than The powdery of 80 mesh, mixes, and after adding the drinking water of 1.5 ~ 2.5 times of mixture weight to boil 20 ~ 35 minutes, packs i.e. Become.
3. the health medicine of the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis as claimed in claim 1, by each raw material organic extractant solution Method is respectively prepared extract, mix, and makes oral liquid and packs.
4. the health medicine of the preventing and treating pneumoconiosis containing Radix Angelicae Sinensis as claimed in claim 1, each raw material is respectively prepared and is no less than The powdery of 80 mesh, mixes, and is divided into parcel, makes fast tea bag packaging.
CN201511013259.0A 2015-12-31 2015-12-31 Radix angelicae sinensis containing health care medicine for preventing and treating pneumoconiosis Pending CN106389806A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103071120A (en) * 2013-01-31 2013-05-01 张玉康 Medicine for treating silicosis
CN103461605A (en) * 2013-09-24 2013-12-25 北京绿源求证科技发展有限责任公司 Food health maintenance tea granules for treating silicosis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103071120A (en) * 2013-01-31 2013-05-01 张玉康 Medicine for treating silicosis
CN103461605A (en) * 2013-09-24 2013-12-25 北京绿源求证科技发展有限责任公司 Food health maintenance tea granules for treating silicosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李开琴等: "矽肺的中医辨证浅析", 《内蒙古中医药》 *

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Application publication date: 20170215