CN106389629A - Traditional Chinese medicine composition for treating eczema pruritus and preparing method thereof - Google Patents

Traditional Chinese medicine composition for treating eczema pruritus and preparing method thereof Download PDF

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CN106389629A
CN106389629A CN201610943380.1A CN201610943380A CN106389629A CN 106389629 A CN106389629 A CN 106389629A CN 201610943380 A CN201610943380 A CN 201610943380A CN 106389629 A CN106389629 A CN 106389629A
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chinese medicine
medicine composition
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eczema
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杨均初
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/754Evodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The invention relates to a traditional Chinese medicine composition for treating eczema pruritus and a preparing method thereof. The traditional Chinese medicine composition is prepared from persicaria perfoliata, clerodendrum fortunatum, rubus parvifolius, fructus evodiae, thymifoious euphorbia herbs, folium artemisiae argyi and the like. The invention also provides the preparing method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is mainly used for treating eczema pruritus.

Description

A kind of Chinese medicine composition treating eczema itching over the body and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines is and in particular to a kind of Chinese medicine composition treating eczema itching over the body and preparation method thereof.
Background technology
Eczema is a kind of allergic skin disease of common easy recurrence, is apt to occur in head, extremity bend side and perineum etc. Position, is in often general or symmetry distribution.Eczema is multi-cause disease it is considered that closely related with allergy.Part with Endocrine dysfunction, autonomic nervous dysfunction is relevant;Inherited genetic factorss are also one of primary disease factor.Cause of disease complexity is controlled to primary disease Treat and bring certain difficulty.
The name of disease of ancient Chinese medicine document no " eczema ", according to its Clinical symptoms, Master Home in " acute eczema ", " noxious dampness " it Category, but according to its site of pathological change difference, title is different.It is " ecthyma " as be born in shank, be born in the fossa cubitalis or muscular prominence fossa part " four Curved wind ", is born in scrotum no less than 10 kinds of titles such as " eczema of scrotum ".Earliest record to primary disease, sees《Huang di's Canon of Medicine》.As 《Plain Questions the most pure virginity will be discussed greatly》In touch upon and say in nineteen items of pathogenesis:" all sufferings skin ulcers, come under the heart." Han dynasty Zhang Zhongjing exists《Gold is deficient Outline》In point out:" acute eczema, Rhizoma Coptidis powder master it." first propose Chinese traditional treatment primary disease side's medicine.Afterwards, ancient Chinese medicine doctor is to this The understanding of disease is constantly deepened, and such as Sui Dynasty Chao Yuanfang (550-630 A.D.) exists《The General Treatise on the Cause and Symptoms of Diseases》Described in:" all long skin ulcer person ¨ ¨ are taken advantage of by rheumatism, damp and hot Xiang Bo, therefore head body all gives birth to skin ulcer." explicitly point out wind, wet, hot three evil be main pathogenic, tentatively established the disease of primary disease Because of pathogenesis basis.Ming Dynasty's Chen Shigong exists《Waike Zhengzong, Orthodox Manual of External Diseases》Supplement improper diet, the damp and hot cause of disease of interior life, and propose to be dissipated with Pulvis concha Mactrae Outer treating method.Qing Dynasty Wu Qian exists《Yizong Jinjian》Description:" this disease is come into being as scabies, prurituss no when, spread more than, grab Tianjin yellow fluid, wet Excessive in blocks, formed by the wet wind-engaging of heart-fire spleen." narration of not only clinical symptoms of primary disease having been made in greater detail, and by endogenous cause of ill and Exopathogenic factor organically combines.Discussed above show, ancient medicine treatment primary disease have accumulated more rich experience.
Modern Chinese medicine treats the clinical report of eczema, sees nineteen fifty-three earliest.From the sixties, clinical article gradually increases Many, there is case to report, also have the large sample observationses of more than hundred, advocate to combine with external treatment with for oral administration more, also have application The report of acupuncture and moxibustion therapy primary disease.Enter eight, after the nineties, on the basis of a large amount of practice, to sides such as the etiology and pathogenesis of primary disease Face has carried out deep people's investigation.As the cause of disease to eczema, always thinking doctor more with wind, wet, hot, malicious based on, by Long-term clinical Observe, find that blood-deficiency and wind-dry is also that the pathology machine of primary disease one of turns.Differentiation of symptoms and signs for classification of syndrome aspect is just progressively tending to unification.Treatment aspect, On the basis of Chinese medicine for oral administration is laid equal stress on external treatment, excavate out acupuncture, magnetic therapy, folk prescription proved recipe therapy again, so that curative effect is carried further High.
Content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition treating eczema itching over the body;
It is a further object of the present invention to provide a kind of preparation method of the Chinese medicine composition treating eczema itching over the body.
The purpose of the present invention is to be realized by following technical scheme:
The Chinese medicine composition for the treatment of eczema itching over the body of the present invention, is to be prepared from by the raw material of Chinese medicine of following weight portion:
Herba Polygoni Perfoliati 15-35 part, triangle bubble 25-45 part, Rubus Parvifolius L. 15-35 part, Fructus Evodiae 5-25 part, Herba Euphorbiae Thymifoliae 15-35 part, Folium Artemisiae Argyi 5-25 part.
Preferably, it is to be prepared from by the raw material of Chinese medicine of following weight portion:
Herba Polygoni Perfoliati 20-30 part, triangle bubble 30-40 part, Rubus Parvifolius L. 20-30 part, Fructus Evodiae 10-20 part, Herba Euphorbiae Thymifoliae 20-30 part, Chinese mugwort Leaf 10-20 part.
The following is the crude drug source of Chinese medicine preparation of the present invention:
Herba Polygoni Perfoliati, is the herb of polygonaceae plant Herba Polygoni Perfoliati.【Nature and flavor】Bitter, put down.【Indication】Inducing diuresis to remove edema, heat clearing away, promoting blood circulation, Removing toxic substances.Control edema, jaundice, have loose bowels, malaria, dysentery, pertussis, stranguria with turbid discharge, erysipelas, scrofula, eczema, scabies.
Triangle steeps, and is herb or the fruit of sapindaceous plant Cardiospermum halicacabum.【Nature and flavor】Bitter;Pungent;Cold【Indication】Heat clearing away Dampness removing;Removing pathogenic heat from blood and toxic substance from the body.Main jaundice;Stranguria;Eczema;Furuncle swelling toxin;Venom;Traumatic injury.
Rubus Parvifolius L., rose family rubus plant Rubus Parvifolius L. Rubus parvifolius., is used as medicine with root or stem, leaf.【Nature and flavor】 Bitter, puckery, cool.【Indication】Clearing away heat and cooling blood, eliminating stagnation, pain relieving, inducing diuresis to remove edema.For cold, fever, laryngopharynx swelling and pain, spitting of blood, tell Blood, dysentery, enteritis, hepatitis, hepatosplenomegaly, oedema due to nephritis, urinary system infection, calculus, menoxenia, leucorrhea, rheumatic ostalgia, falls Beat and swell and ache;Eczema, dermatitis are controlled in external.
Fructus Evodiae, is rutaceae Fructus Evodiae Evodia rutaecarpa(Juss.)Benth., Shi Hu Evodia rutaecarpa(Juss.)Benth. var. officinalis (Dode)Huang or thin hair Fructus Evodiae Evodia rutaecarpa (Juss.)Benth. var. bodinieri (Dode)Huang is dried almost ripe fruit.【Nature and flavor】Pungent, Hardship, heat;Slightly poisonous.【Return through】Return liver, spleen, stomach, kidney channel.【Indication】Dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For Headache due to JUE YIN disorder, cold hernia stomachache, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, abdominal distention, vomit acid regurgitation, Diarrhoea, external treatment aphtha;High blood Pressure.
Herba Euphorbiae Thymifoliae, is Euphorbiaceae euphorbia Euphorbia thymifolia Euphorbia thymifolia L., with all herbal medicine. 【Nature and flavor】Micro- sour, puckery, micro- cool.【Indication】Clearing away heat-damp and promoting diuresis, convergence is antipruritic.Bacillary dysentery, enteritis, diarrhea, bleeding hemorrhoidss; Eczema, allergic dermatitises, skin pruritus are controlled in external.
Folium Artemisiae Argyi, is the dried leaves of feverfew Chinese mugwort Artemisia argyi Levl. et Vant..【Nature and flavor】It is pungent, bitter, Temperature;Slightly poisonous.【Return through】Return liver, spleen, kidney channel.【Indication】Dispersing cold for relieving pain, warming the meridian for stopping bleeding.For few abdomen crymodynia, through trembling with fear not Adjust, uterus cold infertile, spit blood, epistaxis, metrorrhagia is through many, gestation hemorrhage;External treatment skin pruritus.Vinegar Chinese mugwort charcoal warming the meridian for stopping bleeding.For deficiency and coldness Property bleeding.
Another aspect of the present invention there is provided the preparation method of the active component of Chinese medicine composition of the present invention, and the method is Ethanol extraction using water extraction or 40-80% concentration expressed in percentage by volume is prepared from.Concrete preparation method is as follows:
Scheme one:Take whole medical materials, extracting in water 2-3 time after mixing, each amount of water is equivalent to 6-12 times of medical material gross weight, Extraction time is 1-3 hour every time, united extraction liquid, filtration, and it is 1.15-1.20 that filtrate is concentrated into relative density when 70-80 DEG C Clear paste, obtain final product active component.
Scheme two:Take whole medical materials, after mixing, use 40-80% alcohol reflux 2-3 time, each ethanol consumption is medical material total amount 4-10 times, extraction time is 1-4 hour, and united extraction liquid filters, filtrate is concentrated into relative density when 70-80 DEG C and is The clear paste of 1.15-1.20, obtains final product active component.
Scheme three:Take whole medical materials, extracting in water 2-3 time after mixing, each amount of water is equivalent to the 6- of medical material gross weight 12 times, each extraction time is 1-3 hour, united extraction liquid, filtration, and filtrate is concentrated into relative density when 70-80 DEG C and is The clear paste of 1.15-1.20, adds ethanol, makes alcohol content be 40-70%, stands 12-24 hour, filtration, filtrate is concentrated into 70-80 DEG C when relative density be 1.10-1.25 extractum, obtain final product active component.
The Chinese medicine composition for the treatment of eczema itching over the body of the present invention, can also be joined with pharmaceutically acceptable carrier Close, make various oral formulations, such as pill, tablet, capsule, oral liquid, syrup, mixture etc..
The pharmaceutically acceptable carrier of the present invention is including but not limited to following:
Oral formulations:
Diluent:Starch, Icing Sugar, Lactose, dextrin, Microcrystalline Cellulose, inorganic salt, sugar alcohols etc..
Wetting agent and binding agent:Purified water, ethanol, gelatin, Polyethylene Glycol, cellulose derivative etc..
Disintegrating agent:Starch, carboxymethyl starch sodium, cellulose derivative, Crospovidone etc..
Lubricant:Magnesium stearate, micropowder silica gel, Pulvis Talci, Polyethylene Glycol etc..
Cosolvent:Water, ethanol, glycerol, propylene glycol, liquid Paraffin, vegetable oil etc..
Correctivess:Sucrose, monosaccharide, aromatic etc..
Preservative:Benzoic acid, sorbic acid, methyl ester, ethyl ester, propyl ester etc..
Method 1:Tablet
Take scheme one one of to scheme three gained active component, add tablet to commonly use adjuvant, routinely production method is prepared into this Invention tablet.
Above-mentioned tablet is commonly used adjuvant and is included one of diluent, wetting agent, binding agent, disintegrating agent, lubricant or whole.
Method 2:Capsule
Take scheme one one of to scheme three gained active component, add capsule to commonly use adjuvant, routinely production method is prepared into Capsule of the present invention.
Above-mentioned capsule is commonly used adjuvant and is included one of diluent, wetting agent, binding agent, disintegrating agent, lubricant or whole.
Method 3:Syrup
Take scheme one one of to scheme three gained active component, add syrup to commonly use adjuvant, routinely production method is prepared into Syrup of the present invention.
Above-mentioned syrup is commonly used adjuvant and is included one of correctivess, preservative, cosolvent or whole.
Method 4:Mixture
Take scheme one one of to scheme three gained active component, add mixture to commonly use adjuvant, routinely production method is prepared into this Invention mixture.
Above-mentioned mixture is commonly used adjuvant and is included one of correctivess, preservative or whole.
Method 5:Oral liquid
Take scheme one one of to scheme three gained active component, dissolving after-purification, concentration, add oral liquid to commonly use adjuvant, by normal Rule production method is prepared into oral liquid of the present invention.
The applicant reads document at all times extensive, with Traditional Chinese medical theory, in conjunction with modern diagnosis and treatment experience, finds one kind The Chinese medicine composition for the treatment of eczema itching over the body disease.Square intermediate cam bubble clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body;Herba Polygoni Perfoliati heat-clearing and toxic substances removing, dampness removing, For monarch drug in side;Rubus Parvifolius L. clearing away heat and cooling blood, Herba Euphorbiae Thymifoliae clearing away heat-damp and promoting diuresis are antipruritic and are minister;Fructus Evodiae, Folium Artemisiae Argyi cold expelling dampness removing, and be Assistant.Take a broad view of full side, there is the effect of heat-clearing and toxic substances removing, blood-cooling itch-relieving, cold expelling dampness removing.Treatment for eczema itching over the body.
A kind of Chinese medicine composition treating eczema itching over the body that the present invention provides has advantages below:
1st, the composite preparation that the present invention provides safely and effectively, has the effect of heat-clearing and toxic substances removing, blood-cooling itch-relieving, cold expelling dampness removing.With Treatment in eczema itching over the body.
2nd, the Chinese medicinal composition preparation that the present invention provides, scientific formulation is reasonable, process is simple, in good taste, low cost.
Specific embodiment
Further illustrate the present invention below by embodiment.It should be understood that embodiments of the invention are for illustrating The present invention rather than limitation of the present invention.Broadly fall into the present invention according to the simple modifications that the essence of the present invention is carried out to the present invention Claimed scope.Unless otherwise stated, the percent of the amount of alcohol in the present invention is percentage by volume, and v/v represents solution Volume ratio.
Embodiment 1 granule
Weigh Herba Polygoni Perfoliati 15g, triangle bubble 25g, Rubus Parvifolius L. 15g, Fructus Evodiae 5g, Herba Euphorbiae Thymifoliae 15g, Folium Artemisiae Argyi 5g.Extracting in water 3 times, Three amount of water are respectively 12 times, 8 times, 6 times of medical material gross weight, and three extraction times are respectively 3 hours, 2 hours, 1 hour, United extraction liquid, filtration, when filtrate is concentrated into 70 DEG C, relative density is 1.25 clear paste, adds starch, dextrin, pelletize, be dried, Granulate obtains final product.
Embodiment 2 tablet
Weigh Herba Polygoni Perfoliati 35g, triangle bubble 45g, Rubus Parvifolius L. 35g, Fructus Evodiae 25g, Herba Euphorbiae Thymifoliae 35g, Folium Artemisiae Argyi 25g.Use alcohol reflux Extract 2 times, each concentration of alcohol is respectively 80%, 60%, each ethanol consumption is respectively 10 times, 8 times of medical material total amount, during extraction Between be respectively 4 hours, 3 hours, united extraction liquid, filter, when filtrate is concentrated into 80 DEG C, relative density is 1.10 extractum, add Supplementary product starch, ethanol, Pulvis Talci, prepared tablet.
Embodiment 3 tablet
Weigh Herba Polygoni Perfoliati 20g, triangle bubble 30g, Rubus Parvifolius L. 20g, Fructus Evodiae 10g, Herba Euphorbiae Thymifoliae 20g, Folium Artemisiae Argyi 10g.Extracting in water 3 Secondary, three times amount of water is respectively equivalent to 12 times of medical material gross weight, 8 times, 6 times, 3 hours respectively each extraction time, 2 hours, 1 Hour, united extraction liquid, filtration, when filtrate is concentrated into 70 DEG C, relative density is 1.20 clear paste, adds ethanol, makes the alcohol content be 40%, stand 24 hours, filtration, filtrate is concentrated into the extractum that relative density when filtrate is concentrated into 70 DEG C is 1.10, adds adjuvant to form sediment Powder, ethanol, Pulvis Talci, prepared tablet.
Embodiment 4 capsule
Weigh Herba Polygoni Perfoliati 30g, triangle bubble 40g, Rubus Parvifolius L. 30g, Fructus Evodiae 20g, Herba Euphorbiae Thymifoliae 30g, Folium Artemisiae Argyi 20g.Returned with 40% ethanol Stream extracts 3 times, and each ethanol consumption is respectively 10 times, 8 times, 4 times of medical material total amount, 3 hours respectively extraction time, 2 hours, 1 Hour, united extraction liquid, filter, filtrate concentrate 60 DEG C when relative density be 1.25 extractum, in extractum add supplementary product starch, Ethanol, dextrin, magnesium stearate, make capsule according to a conventional method.
Embodiment 5 granule
Weigh Herba Polygoni Perfoliati 25g, triangle bubble 35g, Rubus Parvifolius L. 25g, Fructus Evodiae 15g, Herba Euphorbiae Thymifoliae 25g, Folium Artemisiae Argyi 15g.Extracting in water 2 Secondary, each amount of water is respectively equivalent to 12 times of medical material gross weight, 10 times, and each extraction time is respectively 3 hours, 2 hours, closes And extracting solution, filtration, filtrate is concentrated into the clear paste that relative density at 80 DEG C is 1.05, adds ethanol, makes alcohol content be 70%, quiet Put 12 hours, filtration, when filtrate is concentrated into 70 DEG C, relative density is 1.25 extractum, add starch, dextrin, pelletize, dry, whole Grain obtains final product.
Embodiment 6 syrup
Weigh Herba Polygoni Perfoliati 18g, triangle bubble 28g, Rubus Parvifolius L. 18g, Fructus Evodiae 8g, Herba Euphorbiae Thymifoliae 18g, Folium Artemisiae Argyi 8g.Extracting in water 2 times, Amount of water is respectively 10 times, 8 times of medical material gross weight twice, twice extraction time respectively 2 hours, 1 hour, united extraction Liquid, filtration, when filtrate is concentrated into 80 DEG C, relative density is 1.10 extractum.Syrup adjuvant sucrose, Pyrusussuriensiss are added in extractum Acid, water stir, prepared syrup.
Embodiment 7 oral liquid
Weigh Herba Polygoni Perfoliati 23g, triangle bubble 32g, Rubus Parvifolius L. 23g, Fructus Evodiae 12g, Herba Euphorbiae Thymifoliae 23g, Folium Artemisiae Argyi 12g.Extracting in water 2 Secondary, amount of water is respectively 10 times, 8 times of medical material gross weight twice, twice extraction time respectively 2 hours, 1 hour, and merging carries Take liquid, filtration, when filtrate is concentrated into 80 DEG C, relative density is 1.10 extractum, in extractum add adjuvant Mannitol, sorbic acid, Water stirs, subpackage, prepared oral liquid.
Embodiment 8 mixture
Weigh Herba Polygoni Perfoliati 28g, triangle bubble 38g, Rubus Parvifolius L. 28g, Fructus Evodiae 18g, Herba Euphorbiae Thymifoliae 28g, Folium Artemisiae Argyi 18g.Extracting in water 3 Secondary, three times amount of water is respectively equivalent to 12 times of medical material gross weight, 8 times, 6 times, 3 hours respectively each extraction time, 2 hours, 1 Hour, united extraction liquid, filtration, filtrate concentration ad pond om is 3 times of medical material gross weight, fill, addition mixture adjuvant sucrose, Ethyl ester, water, sorbic acid stir, prepared mixture.
Embodiment 9 powder
Weigh Herba Polygoni Perfoliati 32g, triangle bubble 42g, Rubus Parvifolius L. 32g, Fructus Evodiae 23g, Herba Euphorbiae Thymifoliae 32g, Folium Artemisiae Argyi 23g.Pulverize, sieve, Obtain final product.
Model case
1st, multitude XX, man, 38 years old.Suffer from eczema 4 years, meet winter to disappear, often send out to spring.Can not go out for every to work, misery is very. Endo-medicine or medication washout affected part effect be not all good.Examine meeting portion and two handss forearms, huckle are abound with cerise erythema, mound Rash, but no blister, substantially, prurituss are very acute for edema, and burning sensation substantially, has thirsty, dry stool, pale tongue, white and thin fur, moderate pulse concurrently.Card Belong to dysfunction of the spleen in transportation, retention of damp-heat in the interior, diseases caused by exogenous pathogenic factor rheumatic fever.Give the embodiment of the present invention 4 to treat, take medicine 3 days, rash disappear itch flat.Take 7 space-baseds This recovery from illness.Subsequently take 5 days, pertinacious disease is cured.
2nd, magnificent X, female, 47 years old.No obvious inducement appearance face, napex, back erythra before 5 days, prominent skin, pale red, Sparse distribution, slightly itches, and that grabs goes out pus point, and that grabs goes out a little muddy water thing like as pus, does not press from both sides blood.Give the embodiment of the present invention 8 to control Treat, have within 1 day pox of itching to see and subtract, after 3 days pox section itch several only;Continue 3 days, pox of itching section disappears, and so far there are no remakes.
Although, above used general explanation, specific embodiment and test, the present invention made retouch in detail State, but on the basis of the present invention, it can be made some modifications or improvements, this is apparent to those skilled in the art 's.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, belong to claimed Scope.

Claims (7)

1. a kind of Chinese medicine composition treating eczema itching over the body is it is characterised in that it is by the raw material of Chinese medicine preparation of following weight portion Become:
Herba Polygoni Perfoliati 15-35 part, triangle bubble 25-45 part, Rubus Parvifolius L. 15-35 part, Fructus Evodiae 5-25 part, Herba Euphorbiae Thymifoliae 15-35 part, Folium Artemisiae Argyi 5-25 part.
2. the Chinese medicine composition for the treatment of eczema itching over the body as claimed in claim 1 is it is characterised in that it is by the following weight of inclusion The raw material of Chinese medicine of part is prepared from:
Herba Polygoni Perfoliati 20-30 part, triangle bubble 30-40 part, Rubus Parvifolius L. 20-30 part, Fructus Evodiae 10-20 part, Herba Euphorbiae Thymifoliae 20-30 part, Chinese mugwort Leaf 10-20 part.
3. the Chinese medicine composition for the treatment of eczema itching over the body as claimed in claim 1 or 2 is it is characterised in that its active component is to adopt It is prepared from the ethanol extraction of water extraction or 40-80% concentration expressed in percentage by volume.
4. the Chinese medicine composition for the treatment of eczema itching over the body as claimed in claim 3 is it is characterised in that its active component is to pass through Following methods are prepared from:Take whole medical materials, extracting in water 2-3 time after mixing, each amount of water is equivalent to medical material gross weight 6-12 times, each extraction time is 1-3 hour, united extraction liquid, filtration, and filtrate is concentrated into relative density when 70-80 DEG C and is The clear paste of 1.15-1.20, obtains final product active component.
5. the Chinese medicine composition for the treatment of eczema itching over the body as claimed in claim 3 is it is characterised in that its active component is to pass through Following methods are prepared from:Take whole medical materials, after mixing, use 40-80% alcohol reflux 2-3 time, each ethanol consumption is 4-10 times of medical material total amount, extraction time is 1-4 hour, and united extraction liquid filters, filtrate is concentrated into relatively close when 70-80 DEG C Spend the clear paste for 1.15-1.20, obtain final product active component.
6. the Chinese medicine composition for the treatment of eczema itching over the body as claimed in claim 3 is it is characterised in that its active component is to pass through Following methods are prepared from:Take whole medical materials, extracting in water 2-3 time after mixing, each amount of water is equivalent to medical material gross weight 6-12 times, each extraction time is 1-3 hour, united extraction liquid, filtration, and filtrate is concentrated into relative density when 70-80 DEG C and is The clear paste of 1.15-1.20, adds ethanol, makes alcohol content be 40-70%, stands 12-24 hour, filtration, filtrate is concentrated into 70-80 DEG C when relative density be 1.10-1.25 extractum, obtain final product active component.
7. a kind of preparation treating eczema itching over the body, the Chinese medicine composition for the treatment of eczema itching over the body described in claim 1-6 and doctor Pharmaceutically acceptable carrier prepares and forms.
CN201610943380.1A 2016-11-02 2016-11-02 Traditional Chinese medicine composition for treating eczema pruritus and preparing method thereof Withdrawn CN106389629A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107715077A (en) * 2017-12-08 2018-02-23 叶盛清 A kind of Chinese medicine composition for treating palpitaition and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104383378A (en) * 2014-10-30 2015-03-04 梁春林 Traditional Chinese medicine composition for treating eczema pruritus and preparation method of traditional Chinese medicine composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104383378A (en) * 2014-10-30 2015-03-04 梁春林 Traditional Chinese medicine composition for treating eczema pruritus and preparation method of traditional Chinese medicine composition

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107715077A (en) * 2017-12-08 2018-02-23 叶盛清 A kind of Chinese medicine composition for treating palpitaition and preparation method thereof

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Application publication date: 20170215