CN106362055A - 一种抗肿瘤的组合物及其制备方法 - Google Patents
一种抗肿瘤的组合物及其制备方法 Download PDFInfo
- Publication number
- CN106362055A CN106362055A CN201610928553.2A CN201610928553A CN106362055A CN 106362055 A CN106362055 A CN 106362055A CN 201610928553 A CN201610928553 A CN 201610928553A CN 106362055 A CN106362055 A CN 106362055A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- chinese medicine
- compositionss
- raw material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 9
- 230000000259 anti-tumor effect Effects 0.000 title claims abstract description 6
- 238000002360 preparation method Methods 0.000 title claims description 6
- 241001265525 Edgeworthia chrysantha Species 0.000 claims abstract description 11
- 241001070941 Castanea Species 0.000 claims abstract description 3
- 235000014036 Castanea Nutrition 0.000 claims abstract 2
- 239000007788 liquid Substances 0.000 claims description 23
- 239000003814 drug Substances 0.000 claims description 18
- 239000002994 raw material Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 230000000118 anti-neoplastic effect Effects 0.000 claims description 12
- 244000025254 Cannabis sativa Species 0.000 claims description 10
- 241001428166 Eucheuma Species 0.000 claims description 10
- 241000628997 Flos Species 0.000 claims description 10
- 241000212906 Aeschynomene Species 0.000 claims description 9
- 241000220317 Rosa Species 0.000 claims description 9
- 241001656875 Sarcococca ruscifolia Species 0.000 claims description 8
- 238000001914 filtration Methods 0.000 claims description 6
- 206010004542 Bezoar Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 abstract description 13
- 210000004185 liver Anatomy 0.000 abstract description 11
- 239000008280 blood Substances 0.000 abstract description 10
- 210000004369 blood Anatomy 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 9
- 238000011282 treatment Methods 0.000 abstract description 9
- 231100000331 toxic Toxicity 0.000 abstract description 6
- 230000002588 toxic effect Effects 0.000 abstract description 6
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 5
- 238000002512 chemotherapy Methods 0.000 abstract description 5
- 208000026435 phlegm Diseases 0.000 abstract description 5
- 235000013399 edible fruits Nutrition 0.000 abstract description 4
- 230000001737 promoting effect Effects 0.000 abstract description 4
- 238000001959 radiotherapy Methods 0.000 abstract description 4
- 230000017531 blood circulation Effects 0.000 abstract description 3
- 230000001105 regulatory effect Effects 0.000 abstract description 3
- 241001547453 Sarcococca Species 0.000 abstract description 2
- 235000008240 Abelmoschus moschatus subsp tuberosus Nutrition 0.000 abstract 1
- 241000904515 Abelmoschus sagittifolius Species 0.000 abstract 1
- 235000004051 Aeschynomene indica Nutrition 0.000 abstract 1
- 241000483908 Aeschynomene sensitiva Species 0.000 abstract 1
- 241001061906 Caragana Species 0.000 abstract 1
- 241000206671 Gelidium amansii Species 0.000 abstract 1
- 241000608847 Gnaphalium Species 0.000 abstract 1
- 240000007049 Juglans regia Species 0.000 abstract 1
- 235000009496 Juglans regia Nutrition 0.000 abstract 1
- 244000022370 Symplocos paniculata Species 0.000 abstract 1
- 235000003337 Symplocos paniculata Nutrition 0.000 abstract 1
- 235000017537 Vaccinium myrtillus Nutrition 0.000 abstract 1
- 244000078534 Vaccinium myrtillus Species 0.000 abstract 1
- 241000278700 Wikstroemia canescens Species 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 235000020234 walnut Nutrition 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 description 7
- 210000000952 spleen Anatomy 0.000 description 7
- 206010011224 Cough Diseases 0.000 description 6
- 208000002193 Pain Diseases 0.000 description 5
- 235000009508 confectionery Nutrition 0.000 description 5
- 239000006071 cream Substances 0.000 description 5
- 238000005453 pelletization Methods 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 206010012735 Diarrhoea Diseases 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 208000001848 dysentery Diseases 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- 208000003251 Pruritus Diseases 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 208000004396 mastitis Diseases 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- 208000004998 Abdominal Pain Diseases 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 208000005171 Dysmenorrhea Diseases 0.000 description 2
- 206010013935 Dysmenorrhoea Diseases 0.000 description 2
- 206010017553 Furuncle Diseases 0.000 description 2
- 208000007882 Gastritis Diseases 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 208000015817 Infant Nutrition disease Diseases 0.000 description 2
- 235000019082 Osmanthus Nutrition 0.000 description 2
- 241000333181 Osmanthus Species 0.000 description 2
- 206010036790 Productive cough Diseases 0.000 description 2
- 241000914162 Rosa bella Species 0.000 description 2
- 208000007107 Stomach Ulcer Diseases 0.000 description 2
- 241001534930 Thymelaeaceae Species 0.000 description 2
- 206010044565 Tremor Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 208000035269 cancer or benign tumor Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 201000006549 dyspepsia Diseases 0.000 description 2
- 206010016256 fatigue Diseases 0.000 description 2
- 201000005917 gastric ulcer Diseases 0.000 description 2
- 208000035861 hematochezia Diseases 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 201000003265 lymphadenitis Diseases 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 230000003340 mental effect Effects 0.000 description 2
- 208000024794 sputum Diseases 0.000 description 2
- 210000003802 sputum Anatomy 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 230000008736 traumatic injury Effects 0.000 description 2
- 210000003932 urinary bladder Anatomy 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 241001075517 Abelmoschus Species 0.000 description 1
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 201000000736 Amenorrhea Diseases 0.000 description 1
- 206010001928 Amenorrhoea Diseases 0.000 description 1
- 206010002953 Aphonia Diseases 0.000 description 1
- 206010003011 Appendicitis Diseases 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 241000223019 Caragana korshinskii Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 208000005623 Carcinogenesis Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 241000758791 Juglandaceae Species 0.000 description 1
- 241000219071 Malvaceae Species 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010034038 Parotitis Diseases 0.000 description 1
- 201000005702 Pertussis Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 235000016607 Rosa bella Nutrition 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 206010067868 Skin mass Diseases 0.000 description 1
- 241000828356 Solieria <tachinid fly> Species 0.000 description 1
- 206010041660 Splenomegaly Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 241001060368 Symplocaceae Species 0.000 description 1
- 241000233945 Typhaceae Species 0.000 description 1
- 208000024780 Urticaria Diseases 0.000 description 1
- 206010046788 Uterine haemorrhage Diseases 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 208000005946 Xerostomia Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 201000007201 aphasia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000621 bronchi Anatomy 0.000 description 1
- 230000036952 cancer formation Effects 0.000 description 1
- 231100000504 carcinogenesis Toxicity 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000023652 chronic gastritis Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000000366 juvenile effect Effects 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 210000005075 mammary gland Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/52—Juglandaceae (Walnut family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/902—Sparganiaceae (Bur-reed family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明涉及一种抗肿瘤的组合物，由下述重量配比的中药原料组成：火炮草果3‑12份，清香桂5‑8份，南烛叶3‑7份，合萌根2‑5份，柠条根5‑8份，棒棒草3‑5份，结香花5‑10份，湿鼠曲草3‑10份，琼枝5‑12份，白檀3‑5份，黑三棱5‑10份，荛花根3‑5份，胡桃壳5‑8份，栗毛球7‑12份，刺玫果5‑15份。本发明的组合物具有活血化瘀、祛湿化痰、软坚散结、清热解毒、补气养阴、调心柔肝的功效，对肿瘤治疗疗效显著，可单独使用，也可与手术、放疗、化疗同时使用，无毒副作用。
Description
技术领域
本发明属于中药领域，具体涉及一种抗肿瘤的组合物及其制备方法。
背景技术
肿瘤是指机体在各种致瘤因子作用下，局部组织细胞增生所形成的新生物，因为这种新生物多呈占位性块状突起，也称赘生物。肿瘤是目前严重威胁人们生命安全的重大疾病之一，不论国内外，每年都有大量的病人因患肿瘤而死亡。在我国当前的肿瘤治疗有两种模式，即西医治疗与中医治疗。西医治疗目前主要包括手术治疗、放疗与化疗，这三种方法均不同程度的延长了肿瘤病人的生存时间，但是均具有副作用大、治疗不彻底的弊端，不管是手术、放疗或者化疗，对人体正常组织的伤害是也是明显的，都会增加病人的痛苦，并且并不能彻底治愈肿瘤。
发明内容
本发明的目的在于提供一种疗效显著，无毒副作用的抗肿瘤的组合物及其制备方法。
本发明解决其技术问题所采用的技术方案是：一种抗肿瘤的组合物，由下述重量配比的中药原料组成：火炮草果3-12份，清香桂5-8份，南烛叶3-7份，合萌根2-5份，柠条根5-8份，棒棒草3-5份，结香花5-10份，湿鼠曲草3-10份，琼枝5-12份，白檀3-5份，黑三棱5-10份，荛花根3-5份，胡桃壳5-8份，栗毛球7-12份，刺玫果5-15份。
优选的，一种抗肿瘤的组合物，由下述重量配比的中药原料组成：火炮草果5份，清香桂7份，南烛叶5份，合萌根5份，柠条根8份，棒棒草4份，结香花5份，湿鼠曲草8份，琼枝8份，白檀5份，黑三棱7份，荛花根4份，胡桃壳5份，栗毛球10份，刺玫果10份。
上述抗肿瘤组合物的制备方法如下：上述中药原料加水1000毫升，浸泡1小时，然后煎煮一小时取药液，再次加水1000毫升，继续煎煮40分钟，过滤取药液，合并两次药液，分早晚两次服用。也可将煎取的药液进一步制作成丸、膏或散剂。
本发明各中药原料的药理活性如下：
火炮草果，为锦葵科植物箭叶秋葵的果实，甘，淡，平，柔肝补肾；和胃止痛。主肾虚耳聋；胃痛；疳积；少年白发。
清香桂，为黄杨科野扇花属植物清香桂的根，辛、苦，平，理气止痛，祛风活络。用于急、慢性胃炎，胃溃疡，风湿关节痛，跌打损伤。
南烛叶，为杜鹃花科植物乌饭树的叶，酸，涩，性平，归心、脾、肾经，益肠胃；养肝肾。主脾胃气虚；久泻；少食；肝肾不足；腰膝乏力；须发早白。《本草汇言》：益气添精，凉血养筋。
合萌根，为豆科植物田皂角的根，甘苦，寒，归肺、胃、膀胱经，清热利湿，消积，解毒。主血淋，泄泻，痢疾，疳积，目昏，牙痛，疮疖。
柠条根，为豆科植物中间锦鸡儿的根，微辛，温，归心、肝经，益气养阴。主头晕，心悸，气短乏力，高血压病。
棒棒草，为石竹科植物短小孩儿参的干燥块根，甘，苦，微温，补肺；健脾；养阴生津。主肺虚咳嗽；脾虚食少；心悸自汗；疲惫乏力；口干。
结香花，为瑞香科植物结香的花蕾，性平，味淡，养阴安神，明目，祛障翳。用于青盲、翳障、多泪、梦遗、虚淋、失音。
湿鼠曲草，为菊科植物湿鼠曲草的全草，味甘，淡，性平，止咳化痰；调所和中；清热平肝。主支气管炎；胃溃疡；湿热痢疾；疮痈肿毒；高血压病。《东北常用中草药手册》："调中益气，止咳化痰。"
琼枝，为红翎菜科植物琼枝的藻体，甘，咸，寒，归肺、肝、大肠经，清肺化痰；软坚散结；解毒。主痰热咳嗽；瘿瘤痰核；痔疮肿痛或下血；肠炎。
白檀，为山矾科植物白檀的根、叶、花或种子，苦，性微寒，清热解毒，消炎软坚，调气散结，祛风止痒。主乳腺炎；淋巴腺炎；肠痈；疮疖；疝气；荨麻疹；皮肤瘙痒。
黑三棱，为黑三棱科植物黑三棱的干燥块茎，味辛，苦，性平，归肝、脾经，祛瘀通经；破血消症；行气消积。主血滞经闭；痛经；产后瘀阻腹痛；跌打瘀肿；腹中包块；食积腹痛。
荛花根，为瑞香科植物荛花的根，辛，温，舒筋活络；散结消肿。主跌打损伤；筋骨疼痛；腮腺炎；乳腺炎；淋巴腺炎。
胡桃壳，为胡桃科植物胡桃成熟果实的内果皮，苦，涩，性平，止血；止痢；散结消痈；杀虫止痒。主妇女崩漏；痛经；久痢；疟母；乳痈；疥癣；鹅掌风。
栗毛球，为壳斗科植物栗的总苞，甘，涩，性平，清热散结；化痰；止血。主丹毒；瘰疬痰核；百日咳；中风不语；便血；鼻衄。
刺玫果，为蔷薇科植物山刺玫、光叶山刺玫的果实，酸，苦，温，归肝、脾、胃、膀胱经，健脾消食；活血调经；敛肺止咳。主消化不良；食欲不振；脘腹胀痛；腹泻；月经不调；痛经；动脉粥样硬化；肺结咳嗽。《东北常用中草药手册》：健脾理气，养血调经。治消化不良，气滞腹泻，胃痛。
本发明具有以下有益效果：本发明的组合物具有活血化瘀、祛湿化痰、软坚散结、清热解毒、补气养阴、调心柔肝的功效，对肿瘤治疗疗效显著，可单独使用，也可与手术、放疗、化疗同时使用，无毒副作用。
具体实施方式
以下是本发明的具体实施例，对本发明的技术方案做进一步描述，但是本发明的保护范围并不限于这些实施例。凡是不背离本发明构思的改变或等同替代均包括在本发明的保护范围之内。
实施例1
一种抗肿瘤的组合物，由下述重量配比的中药原料组成：火炮草果5份，清香桂7份，南烛叶5份，合萌根5份，柠条根8份，棒棒草4份，结香花5份，湿鼠曲草8份，琼枝8份，白檀5份，黑三棱7份，荛花根4份，胡桃壳5份，栗毛球10份，刺玫果10份。
上述中药原料加水1000毫升，浸泡1小时，然后煎煮一小时取药液，再次加水1000毫升，继续煎煮40分钟，过滤取药液，合并两次药液，分早晚两次服用。也可将煎取的药液进一步制作成丸、膏或散剂。
实施例2
一种抗肿瘤的组合物，由下述重量配比的中药原料组成：火炮草果3份，清香桂8份，南烛叶3份，合萌根4份，柠条根7份，棒棒草5份，结香花8份，湿鼠曲草5份，琼枝5份，白檀4份，黑三棱10份，荛花根3份，胡桃壳7份，栗毛球12份，刺玫果5份。
上述中药原料加水1000毫升，浸泡1小时，然后煎煮一小时取药液，再次加水1000毫升，继续煎煮40分钟，过滤取药液，合并两次药液，分早晚两次服用。也可将煎取的药液进一步制作成丸、膏或散剂。
实施例3
一种抗肿瘤的组合物，由下述重量配比的中药原料组成：火炮草果8份，清香桂5份，南烛叶6份，合萌根3份，柠条根6份，棒棒草4份，结香花10份，湿鼠曲草3份，琼枝12份，白檀3份，黑三棱8份，荛花根5份，胡桃壳6份，栗毛球7份，刺玫果8份。
上述中药原料加水1000毫升，浸泡1小时，然后煎煮一小时取药液，再次加水1000毫升，继续煎煮40分钟，过滤取药液，合并两次药液，分早晚两次服用。也可将煎取的药液进一步制作成丸、膏或散剂。
实施例4
一种抗肿瘤的组合物，由下述重量配比的中药原料组成：火炮草果12份，清香桂6份，南烛叶7份，合萌根2份，柠条根5份，棒棒草3份，结香花7份，湿鼠曲草10份，琼枝10份，白檀3份，黑三棱5份，荛花根4份，胡桃壳8份，栗毛球8份，刺玫果15份。
上述中药原料加水1000毫升，浸泡1小时，然后煎煮一小时取药液，再次加水1000毫升，继续煎煮40分钟，过滤取药液，合并两次药液，分早晚两次服用。也可将煎取的药液进一步制作成丸、膏或散剂。
临床资料
一般资料：共收治肿瘤患者510例，其中男性261例，女性249例，年龄23-75岁，平均年龄50岁。
治疗方法：本发明中药组合物制成水煎剂，每日一剂，一日两次，早晚分服，一个月为一个疗程。
疗效判断标准：
显效：肿瘤减小，免疫力提高，精神饱满，无疼痛感；
有效：肿瘤基本得到抑制，免疫力有所提高，精神欠佳，疼痛减轻；
无效：肿瘤未减小，甚至继续生长，精神状况差，仍有疼痛，症状明显。
治疗结果：经3-6个疗程的治疗，结果统计如下：
| 肿瘤位置 | 例数 | 显效 | 有效 | 无效 | 显效率 | 总有效率 |
| 肺 | 105 | 78 | 22 | 5 | 74.3％ | 95.2％ |
| 肝 | 110 | 77 | 25 | 8 | 70.0％ | 92.7％ |
| 食道 | 98 | 72 | 18 | 8 | 73.5％ | 91.8％ |
| 胃 | 78 | 63 | 9 | 5 | 80.8％ | 92.3％ |
| 淋巴 | 59 | 42 | 11 | 6 | 71.2％ | 89.8％ |
| 乳腺 | 60 | 49 | 8 | 3 | 81.7％ | 95.0％ |
本发明的药物诸药配伍，能抑制肿瘤细胞生长，同时增强机体的免疫力，对肿瘤治疗疗效显著，可单独使用，也可与手术、放疗、化疗同时使用，无毒副作用。
Claims (3)
1.一种抗肿瘤的组合物，其特征在于，由下述重量配比的中药原料组成：火炮草果3-12份，清香桂5-8份，南烛叶3-7份，合萌根2-5份，柠条根5-8份，棒棒草3-5份，结香花5-10份，湿鼠曲草3-10份，琼枝5-12份，白檀3-5份，黑三棱5-10份，荛花根3-5份，胡桃壳5-8份，栗毛球7-12份，刺玫果5-15份。
2.如权利要求1所述的一种抗肿瘤的组合物，其特征在于，由下述重量配比的中药原料组成：火炮草果5份，清香桂7份，南烛叶5份，合萌根5份，柠条根8份，棒棒草4份，结香花5份，湿鼠曲草8份，琼枝8份，白檀5份，黑三棱7份，荛花根4份，胡桃壳5份，栗毛球10份，刺玫果10份。
3.如权利要求1或2所述的一种抗肿瘤的组合物，其特征在于，上述抗肿瘤组合物的制备方法如下：上述中药原料加水1000毫升，浸泡1小时，然后煎煮一小时取药液，再次加水1000毫升，继续煎煮40分钟，过滤取药液，合并两次药液，分早晚两次服用。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610928553.2A CN106362055A (zh) | 2016-10-31 | 2016-10-31 | 一种抗肿瘤的组合物及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610928553.2A CN106362055A (zh) | 2016-10-31 | 2016-10-31 | 一种抗肿瘤的组合物及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106362055A true CN106362055A (zh) | 2017-02-01 |
Family
ID=57896106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610928553.2A Pending CN106362055A (zh) | 2016-10-31 | 2016-10-31 | 一种抗肿瘤的组合物及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106362055A (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107050350A (zh) * | 2017-02-27 | 2017-08-18 | 张弛 | 一种治疗乳腺癌的中药汤剂 |
| CN107496742A (zh) * | 2017-09-14 | 2017-12-22 | 南通荣成医药化工有限公司 | 一种抗肿瘤药物 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101664536A (zh) * | 2009-10-15 | 2010-03-10 | 赵金忠 | 一种抗肿瘤的中药组合物 |
| CN102441137A (zh) * | 2011-11-12 | 2012-05-09 | 汤裕强 | 一种抗肿瘤的中药组合物 |
| CN104825783A (zh) * | 2015-05-18 | 2015-08-12 | 南京中医药大学 | 具有抗肿瘤活性的中药组合物及其制备方法和应用 |
-
2016
- 2016-10-31 CN CN201610928553.2A patent/CN106362055A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101664536A (zh) * | 2009-10-15 | 2010-03-10 | 赵金忠 | 一种抗肿瘤的中药组合物 |
| CN102441137A (zh) * | 2011-11-12 | 2012-05-09 | 汤裕强 | 一种抗肿瘤的中药组合物 |
| CN104825783A (zh) * | 2015-05-18 | 2015-08-12 | 南京中医药大学 | 具有抗肿瘤活性的中药组合物及其制备方法和应用 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107050350A (zh) * | 2017-02-27 | 2017-08-18 | 张弛 | 一种治疗乳腺癌的中药汤剂 |
| CN107496742A (zh) * | 2017-09-14 | 2017-12-22 | 南通荣成医药化工有限公司 | 一种抗肿瘤药物 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103520578B (zh) | 一种治疗口腔溃疡的中药组合物及其制备方法 | |
| CN106362055A (zh) | 一种抗肿瘤的组合物及其制备方法 | |
| CN102038924A (zh) | 一种去屑止痒的药物 | |
| CN103893063A (zh) | 一种减轻化疗后脱发的中药洗发水及其制备方法 | |
| CN107335019A (zh) | 一种用于治疗正、偏头痛的丸剂药物及其制备方法 | |
| CN104689240A (zh) | 一种治疗气滞血瘀型黄褐斑的药物及其制备方法 | |
| CN104587391A (zh) | 一种治疗肠癌的中药配方及其制备方法 | |
| CN104606336A (zh) | 防止外科手术后伤口感染的中药膏剂及其制备方法 | |
| CN103816450B (zh) | 一种治疗类风湿性关节炎的中药 | |
| CN107582791A (zh) | 一种治疗闭经的药物及其制备方法 | |
| CN108245611A (zh) | 一种治疗肺脾气虚咳嗽的灸粉及其制备方法和应用 | |
| CN106361904A (zh) | 用于缓解肿瘤病人化疗副反应的中药组合物 | |
| CN106075160A (zh) | 一种抗肿瘤的药物 | |
| CN106237249A (zh) | 一种用于治疗女性更年期失眠的中药胶囊 | |
| CN106110262A (zh) | 苦参黄柏中药酒 | |
| CN104547431A (zh) | 缓解脑梗塞后遗症的中药片剂及制备方法 | |
| CN114246924A (zh) | 松柏保健膏 | |
| CN104399038A (zh) | 一种治疗胃炎的药物及其制备方法 | |
| CN111249354A (zh) | 一种中药肚脐贴及其制备方法 | |
| CN109663091A (zh) | 一种治疗脾胃湿热型慢性肠炎的中药组合物 | |
| CN107596255A (zh) | 一种用于治疗肾阳衰惫型癃闭的中药组合物及制备方法 | |
| CN107789510A (zh) | 一种用于治疗老年人夜间多尿症的中药胶囊 | |
| CN107789507A (zh) | 一种用于治疗老年人夜间多尿症的中药汤剂 | |
| CN107789511A (zh) | 一种用于治疗夜多尿症的中药汤剂 | |
| CN107789512A (zh) | 一种用于治疗夜多尿症的中药胶囊 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170201 |