CN106345054A - Programmable functional electrical stimulator with real-time feedback function - Google Patents
Programmable functional electrical stimulator with real-time feedback function Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
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Abstract
The invention provides a programmable functional electrical stimulator with a real-time feedback function to solve the problem that the existing functional electrical stimulator fails to meet the requirements for diversity. The programmable functional electrical stimulator comprises a main controller, a power supply module and an analog constant-current output module. The main controller outputs a control signal to the analog constant-current output module according to the instruction of the host computer, and also corrects the control signal which has been outputted to the analog constant-current output module according to the current outputted by the analog constant-current output module. The constant-current output module outputs the current of the corresponding waveform according to the control signal. The power supply module provides the working voltage for the main controller and the analog constant-current output module. The functional electrical stimulator of the invention can receive the control instruction issued by the upper computer in real time to change the electrical stimulation waveform, receive the feedback signal, and provide a plurality of stimulation modes and stimulation pulses to meet the requirements for diversity.
Description
Technical field
The present invention relates to a kind of functional electrical stimulato, particularly to a kind of programmable functions with Real-time Feedback function
Property electrostimulator.
Background technology
Functional electrical stimulato is a kind of equipment acting on human body, can be to human body delivered charge, to reach stimulation
Human nerve or the purpose of muscle, and then reach required such as treatment, correct, suppress pathologic to tremble and other effects.Simultaneously it
Very big effect can be played in scientific research with experiment, the scope that it is applied is wider, has various ways.
Existing functional electrical stimulato, how in the form of open loop, stimulus waveform is fixed it is impossible to enough closed in real time
Ring controls, and not being suitable for trembling etc. as suppression pathologic needs the purposes of Real-time Feedback, has individually the feature of feedback function
The feedback model of electrostimulator and feedback signal more single it is impossible to meet multifarious requirement in scientific experimentss；And it is existing
The stimulus waveform substantially constant of functional electrical stimulato is it is impossible to be modified by program it is impossible to meet multifarious requirement.
Content of the invention
The invention aims to solving existing capability electrostimulator cannot meet multifarious problem, the present invention carries
For a kind of programmable functions electrostimulator with Real-time Feedback function.
The programmable functions electrostimulator with Real-time Feedback function of the present invention, described functional electrical stimulato includes
Master controller, power module and simulation constant current output module；
Master controller, according to the instruction of host computer, to simulation constant current output module output control signal, is additionally operable to according to mould
Intend the electric current of constant current output module output, revise to simulation constant current output module output control signal；
Simulation constant current output module, according to control signal, exports the electric current of respective waveforms；
Power module, is master controller and simulation constant current output module provides running voltage.
Preferably, described master controller, according to the instruction of host computer, to simulation constant current output module output control signal
Including:
According to the instruction of host computer, carry out amplitude modulation, the control signal of output amplitude modulated sinusoid；
According to the instruction of host computer, carry out pulsewidth modulation, the control signal of output pulse width modulated sinusoid；
According to the instruction of host computer, export the control signal of accordingly free waveform.
Preferably, described master controller, according to the instruction of host computer, carries out amplitude modulation, output amplitude modulation is sinusoidal
The control signal of ripple:
Receive basic waveform instruction and the amplitude modulation instruction that host computer sends；
According to the pulsewidth of basic waveform, frequency and amplitude, setting intervalometer and dac transducer in basic waveform instruction；Root
According to current amplitude modulation instruction, it is modulated, obtains modulation amplitude, according to the amplitude obtaining, change dac transducer, according to
Intervalometer and dac transducer, the control signal of output amplitude modulated sinusoid.
Preferably, described master controller, according to the instruction of host computer, carries out pulsewidth modulation, output pulse width modulation is sinusoidal
The control signal of ripple:
According to the pulsewidth of basic waveform, frequency and amplitude, setting intervalometer and dac transducer in basic waveform instruction；Root
According to current pulsewidth modulation instruction, it is modulated, obtains modulation pulsewidth, according to the modulation pulsewidth obtaining, change intervalometer, according to
Intervalometer and dac transducer, the control signal of output pulse width modulated sinusoid.
Preferably, described master controller, according to the instruction of host computer, the control signal of the corresponding free waveform of output:
Receive the free waveform instruction of host computer；
Instructed according to free waveform, determine the waveform of control signal, true according to the frequency of upper transmission free waveform instruction
Determine the frequency of control signal, according to the control signal of the waveform determining and the free waveform of rate-adaptive pacemaker.
Preferably, described master controller, is additionally operable to the electric current according to simulation constant current output module output, to simulation constant current
Output module output control signal is:
According to the electric current of simulation constant current output module output, compared with default theoretical current, change control signal.
Preferably, described controller, is additionally operable to determine whether excessively stream according to the electric current of simulation constant current output module output,
When excessively stream occurs, send alarm signal to host computer, control power module to carry out power-off.
Preferably, described simulation constant current output module includes operational amplifier u1a, n-channel mosfet pipe q1, resistance
R1, resistance r2, resistance r3, resistance r4, resistance r5, resistance r7, resistance r8, electric capacity c2, self- recoverage insurance f1 and controlled commutation electricity
Road；
One end of resistance r3 is used for inputting the control signal of master controller, the other end of resistance r3 and operational amplifier u1a
Signal input part in the same direction connect, one end of resistance r5 is connected with the non-inverting signal input thereof of operational amplifier u1a, resistance r5's
The other end is connected with one end of resistance r7, the source electrode of one end of electric capacity c2, one end of resistance r8 and n-channel mosfet pipe q1 simultaneously
Connect, the other end of the other end of electric capacity c2 and resistance r8 connects simulation ground simultaneously；
Master controller obtains the electric current of simulation constant current output module output according to the other end of resistance r7；
The signal output part of operational amplifier u1a is connected with one end of resistance r4, the other end of resistance r4 and n-channel
The grid of mosfet pipe q1 connects, and one end that the drain electrode of n-channel mosfet pipe q1 insures f1 with self- recoverage is connected, and self- recoverage insures
The other end of f1 is connected with the outfan of controlled commutating circuit；
The sense of current control signal of master controller output inputs to controlled commutating circuit through resistance r1 or through resistance r2, can
Export to human body after the electric current low-pass filtered device filtering of control commutating circuit output.
Preferably, described controlled commutating circuit is the h bridge circuit realized using high pressure optocoupler.
The beneficial effects of the present invention is, the functional electrical stimulato of the present invention can receive what host computer sent in real time
Control instruction is changing electrical stimulation waveforms, and can receive feedback signal；And multiple stimulus modelities and boost pulse are provided
Select, disclosure satisfy that multifarious requirement.
Brief description
Fig. 1 is the principle schematic of the programmable functions electrostimulator with Real-time Feedback function of the present invention.
Fig. 2 is the work process schematic diagram of master controller in specific embodiment.
Fig. 3 is the principle schematic of simulation constant current output module.
Specific embodiment
As shown in figure 1, the programmable functions electrostimulator with Real-time Feedback function of present embodiment, including bluetooth
Communication module, master controller, power module and simulation constant current output module；
Bluetooth communication module, for being responsible for the communication of host computer and master controller；
Master controller, according to the instruction of host computer, to simulation constant current output module output control signal, is additionally operable to according to mould
Intend the electric current of constant current output module output, revise the control signal to simulation constant current output module output；
Simulation constant current output module, according to control signal, exports the electric current of respective waveforms；
Power module, is master controller and simulation constant current output module provides running voltage.
Electrostimulator from stimulus modelity for be broadly divided into two kinds: constant pressure source stimulate and constant-current source stimulate.Constant pressure source pierces
Sharp benefit is in response to speed soon, can regard no regulating time as, stimulus signal can be loaded on human body in time, and in circuit
Voltage stabilization during access failure, can play the protective effect to circuit；But the complexity due to human body impedance, constant pressure source stimulates
Output it is impossible to ensure that electric current stablizing in inside of human body.Constant-current source reaches stabling current and needs certain regulating time, but
Constant-current source effect of stimulation is stable, it is possible to reduce the requirement to electrode slice, and is difficult to cause there is damage to human body on human body
Charge accumulated.Present embodiment selects constant-current source to stimulate the stimulus modelity as functional electrical stimulato.
In present embodiment, simulation constant current output module be functional electrical stimulato function implement part, permissible
Control voltage signal is changed into constant current stimulates output to tissue；Master controller can receive host computer in real time and send
Control instruction changing electrical stimulation waveforms, and feedback signal can be received；And multiple stimulus modelities and boost pulse are provided
Selection, disclosure satisfy that multifarious requirement.Total DC source boosting of input and blood pressure lowering can be separated multichannel by power module
Different constant voltage DC sources, is that each several part is powered.
In preferred embodiment, master controller according to the instruction of host computer, to simulation constant current output module output control signal
Including Three models: amplitude modulation pattern, PWM mode and free waveform pattern；
Amplitude modulation pattern: according to the instruction of host computer, carry out amplitude modulation, the control letter of output amplitude modulated sinusoid
Number；
PWM mode: according to the instruction of host computer, carry out pulsewidth modulation, the control letter of output pulse width modulated sinusoid
Number；
Free waveform pattern: according to the instruction of host computer, export corresponding control signal.
The output of functional electrical stimulato is by the modulation to impulse waveform, obtains corresponding stimulus waveform, acts on
On human body, present embodiment provides three kinds of mode of operations, meets various modulation demands.
As shown in Fig. 2 in preferred embodiment, the work process of amplitude modulation pattern:
Armed state is entered, sending initialization directive by host computer makes stimulator enter after electricity on functional electrical stimulato
Corresponding mode of operation, simultaneously functional electrical stimulato the instruction of host computer is responded, mode initialisation；
Enter under amplitude modulation pattern, be now in two grades of armed states, receive the basic waveform instruction that host computer sends
With amplitude modulation instruction；
According to the pulsewidth of basic waveform, frequency and amplitude, setting intervalometer and dac transducer in basic waveform instruction；Root
According to current amplitude modulation instruction, it is modulated, obtains modulation amplitude, according to the amplitude obtaining, change dac transducer, according to
Intervalometer and dac transducer, the control signal of output amplitude modulated sinusoid；
Meanwhile, simulation constant current output module output current can be converted into sampled voltage by sampling resistor, and by master control
The adc sampling of device processed, the sample rate of adc is fixed by program, and the output current data obtaining has the effect of two aspects: first
Electrical stimulation circuit output state can be monitored, by the contrast to actual current value and theoretical output valve, form two grades of closed loop systems
System, the control signal of change amplitude modulation sine wave, the hardware closed-loop compensating system to continuous current, thus realize more smart
True electrical stimulation waveforms；In addition, current monitoring can also realize safeguard protection, and circuit once occurs excessively stream, directly forbids
The Enable Pin of power module, and host computer is reported to the police it is achieved that overcurrent protection.
As shown in Fig. 2 in preferred embodiment, the work process of PWM mode:
Armed state is entered, sending initialization directive by host computer makes stimulator enter after electricity on functional electrical stimulato
Corresponding mode of operation, simultaneously functional electrical stimulato the instruction of host computer is responded, mode initialisation；
Enter under PWM mode, be now in two grades of armed states, receive the basic waveform instruction that host computer sends
With pulsewidth modulation instruction；
According to the pulsewidth of basic waveform, frequency and amplitude, setting intervalometer and dac transducer in basic waveform instruction；Root
According to current pulsewidth modulation instruction, it is modulated, obtains modulation pulsewidth, according to the modulation pulsewidth obtaining, change intervalometer, according to
Intervalometer and dac transducer, the control signal of output pulse width modulated sinusoid.
Meanwhile, simulation constant current output module output current can be converted into sampled voltage by sampling resistor, and by master control
The adc sampling of device processed, the sample rate of adc is fixed by program, and the output current data obtaining has the effect of two aspects: first
Electrical stimulation circuit output state can be monitored, by the contrast to actual current value and theoretical output valve, form two grades of closed loop systems
System, the control signal of change pulsewidth modulation sine wave, the hardware closed-loop compensating system to continuous current, thus realize more smart
True electrical stimulation waveforms；In addition, current monitoring can also realize safeguard protection, and circuit once occurs excessively stream, directly forbids
The Enable Pin of power module, and host computer is reported to the police it is achieved that overcurrent protection.
As shown in Fig. 2 in preferred embodiment, the work process of free waveform pattern:
Armed state is entered, sending initialization directive by host computer makes stimulator enter after electricity on functional electrical stimulato
Corresponding mode of operation, simultaneously functional electrical stimulato the instruction of host computer is responded, mode initialisation；
Under freedom of entry waveform pattern, it is now in two grades of armed states, receive freely instructing of host computer transmission；
According to free instruction, determine the waveform of control signal, control letter is determined according to the upper frequency freely instructing that sends
Number frequency, according to determine waveform and rate-adaptive pacemaker control signal.
Meanwhile, simulation constant current output module output current can be converted into sampled voltage by sampling resistor, and by master control
The adc sampling of device processed, the sample rate of adc is fixed by program, and the output current data obtaining has the effect of two aspects: first
Electrical stimulation circuit output state can be monitored, by the contrast to actual current value and theoretical output valve, form two grades of closed loop systems
System, changes the control signal of free waveform, the hardware closed-loop compensating system to continuous current, thus realizing more accurately electricity
Stimulus waveform；In addition, current monitoring can also realize safeguard protection, and circuit once occurs excessively stream, direct power module
Enable Pin, and host computer is reported to the police it is achieved that overcurrent protection.
When freedom of entry waveform state, no fix output mode, output current value size be by host computer send from
Determined by the value instructing, frequency is to be sent the frequency freely instructing to determine, that is, functional electrical stimulato can lead to by host computer
Any waveform is simulated in the output crossing " step ", and precision sends the numerical value of instruction by host computer and frequency determines.This pattern is
In order to meet what special requirement of experiment set, the application of functional electrical stimulato is made to have popularity and motility.
Present embodiment selects bi-directional symmetrical square wave as the stimulus waveform of functional electrical stimulato.Two-way square wave is
Two direction of stimulation adopt that amplitude is identical, time identical boost pulse, and electric charge release is fast, bidirectional waveform structure identical it is easy to
Control, do not easily cause charge accumulated, and the charge residue time is short, little to muscle injury.Stimulus waveform is functional electric stimulation
The fundamental wave of device, the principle of functional electrical stimulato is by base wave modulation, to reach corresponding effect of stimulation.
The contraction of human muscle needs to provide constant contractility, the holding of this contractility, is by adjacent motion list
Information transmission between unit completes.When remaining retracted when being upset, moving cell can pass to adjacent moving cell
Pass stimulation, frequency is 6-8hz so that the moving cell of surrounding receives new contraction pulse before a pulse before releasing,
Thus macroscopically keeping the contraction state of muscle, this mode is referred to as asynchronous recruitment method.And functional electrical stimulato electricity irritation is no
Method reaches asynchronously to transmit to each moving cell to stimulate, therefore its principle is to activate all of moving cell so that it is protected simultaneously
Hold contraction, referred to as synchronous recruitment method.In synchronous recruitment method, all moving cells are consistent action, therefore need higher
Stimulus frequency, to maintain its contraction state, typically adopts 20-40hz as stimulus frequency, present embodiment selects 24hz as thorn
The frequency of sharp pulse.But what high stimulus frequency brought is the fatigue of muscle, therefore need to reduce stimulation pulsewidth, general pulsewidth exists
200-500us, present embodiment selects 400us as the stimulation pulsewidth of functional electrical stimulato.The thorn of functional electrical stimulato
Sharp current limit highest must not exceed 100ma, and normal extreme value scope selects in 30-50ma.Generally stimulating current is normal in 5ma
People is sensigenouses, and 10ma-15ma produces significant reaction, and electricity irritation is initially slight sensation of pricking most, with the increase of electric current
Muscle occurs shake, the phenomenon such as tremble, and tremor amplitude becomes positive correlation with size of current.Present embodiment selection function electricity
The carrying current of stimulator is 40ma, and the limiting voltage of selection function electrostimulator is 65v.
In preferred embodiment, as shown in figure 3, simulation constant current output module includes operational amplifier u1a, n-channel
Mosfet pipe q1, resistance r1, resistance r2, resistance r3, resistance r4, resistance r5, resistance r7, resistance r8, electric capacity c2, self- recoverage insurance
F1 and controlled commutating circuit；
One end of resistance r3 is used for inputting the control signal of master controller, the other end of resistance r3 and operational amplifier u1a
Signal input part in the same direction connect, one end of resistance r5 is connected with the non-inverting signal input thereof of operational amplifier u1a, resistance r5's
The other end is connected with one end of resistance r7, the source electrode of one end of electric capacity c2, one end of resistance r8 and n-channel mosfet pipe q1 simultaneously
Connect, the other end of the other end of electric capacity c2 and resistance r8 connects simulation ground simultaneously；
Master controller obtains the electric current of simulation constant current output module output according to the other end of resistance r7；
Master controller utilizes adc to gather the voltage of the other end of resistance r7, then the voltage of collection is carried out analog-to-digital conversion, turns
It is changed to the output current of simulation constant current output module；
The signal output part of operational amplifier u1a is connected with one end of resistance r4, the other end of resistance r4 and n-channel
The grid of mosfet pipe q1 connects, and one end that the drain electrode of n-channel mosfet pipe q1 insures f1 with self- recoverage is connected, and self- recoverage insures
The other end of f1 is connected with the outfan of controlled commutating circuit；
The sense of current control signal of master controller output inputs to controlled commutating circuit through resistance r1 or through resistance r2, can
Export to human body after the electric current low-pass filtered device filtering of control commutating circuit output.
Present embodiment selects the psmn012-100yl of nxp company as n-channel mosfet pipe q1, has high withstand voltage,
Source electrode and drain electrode maximum voltage are 100v, and have good thermal diffusivity, and peak power reaches 238w, and the linearity is good and has
There is high-speed response, its rise time is ns level with the turn-off time, can fully meet the rate request of functional electrical stimulato.
The operational amplifier of present embodiment selects the ada4084-2 of adi company.Two computings of ada4084-2 intension are put
Big device unit, disclosure satisfy that the requirement of functional electrical stimulato two-way output；It is high voltage supply simultaneously, and maximum supply power voltage reaches
To 30v, the voltage range of whole mosfet grid can be covered；Ada4084-2 is track to track input/output, voltage output range
No dead band, can be accurate to and supply voltage, meet precise control to mosfet；It has high cmrr, can
Effectively opposing common mode input noise；It has high slew rate again simultaneously, short between regulation, can greatly meet feature
Electrostimulator circuit is for the requirement of speed.
Because stimulus waveform is bi-directional symmetrical square wave, therefore need to introduce controlled commutating circuit in major loop, to output
Stimulating current on human muscle is commutated.Present embodiment adopts h bridge-type commutation circuit, by four control port controls
The conducting of the different brachium pontis of system and shutoff, thus realize the switching of current direction.
In addition, series connection 50ma self- recoverage insurance in major loop, plays the overcurrent protection effect on hardware；Electric current exports
End adopts single order rc low pass filter, filters out high frequency spurs it is ensured that being input to the pure of the upper waveform of human muscle.Select electricity
Resistance, electric capacity, filter cutoff frequency can be obtained and be about 1447hz.
In preferred embodiment, controlled commutating circuit is the h bridge circuit realized using high pressure optocoupler.
In order to realize the electrical isolation of control circuit and analog circuit, present embodiment will be conventional in h bridge circuit
Mosfet is substituted for 4 high pressure optocouplers it is achieved that Phototube Coupling is it is ensured that the reliability and stability of circuit.Select
The h11d1 optocoupler of fairchild semiconductor company, its withstanding voltage is up to 300v, and maximum is 100ma, Neng Gouman by electric current
Sufficient functional electrical stimulato is for the requirement of voltage and current；It opens and shuts off the time and is 5us, meets functional electric thorn
The rate request of sharp device.
In preferred embodiment, master controller adopts stm32f100c8t6 chip to realize.
The work such as the master controller primary communications of functional electrical stimulato, control, daily management and monitoring.Can receive
From the instruction of host computer, analysis instruction output control voltage；It is capable of current detecting, by software view to stimulus waveform
Carry out feedback regulation and correction；It is capable of whole work of the daily managements such as software overcurrent protection, warning.
In order to meet above-mentioned requirements, present embodiment have selected the stm32f100c8t6 Series of MCU of st company, this
Money microcontroller is based on arm cortex-m3 kernel, has powerful function integration and management and control ability.
Stm32f100c8t6 has 48 pins, contains 37 gpio ports, is capable of the control of h bridge commutating circuit, and refers to
Show the control of lamp alarm lamp auxiliary equipment；Its dominant frequency clock can reach 48mhz, and disposal ability can reach 1.25dmips/
Mhz, and embedded the flash memory of 128kb and the sram internal memory of 8k；It is integrated with powerful peripheral hardware resource, communication
Interface aspect, has embedded 2 spi interfaces, 2 i2c interfaces, 3 usart interfaces, in addition, it contains 2 12-bit's
Dac, the highest speed of response is 1us, the digital control amount of functional electrical stimulato can be converted to two-way analog control voltage
Output, and output accuracy and the speed of response are also satisfied by requirement, and it further comprises the 10 passage adc of 1 10-bit, can be right
Main circuit current is effectively monitored, and in addition, it further comprises 7 intervalometers and powerful interrupt manager
Nvic, disclosure satisfy that the needs such as the daily management of functional electrical stimulato master controller.Additionally, it has the little chi of 9 × 9mm
Very little, it is advantageously implemented miniaturization and the portability of functional electrical stimulato equipment.
Total power supply of the power module of present embodiment is 24v direct-flow voltage regulation source, through power module, is divided into
3.3v, 12v, 65v tri- road D.C. regulated power supply, powers to respectively the different piece of functional electrical stimulato system.
The digital circuit that DC voltage-stabilizing 3.3v power supply supplies master controller uses, the ginseng of the dac being simultaneously also embedded into and adc
Examine voltage, therefore need to meet good precision.Have selected the tps62177 line style regulated power supply chip of ti company, its principle is
Ldo line style mu balanced circuit, in 4.75v-28v, output voltage stabilizing is 3.3v to input voltage range, high precision, error within 2%,
Output maximum current is 1200ma, disclosure satisfy that functional electrical stimulato system requirements.
DC voltage-stabilizing 12v power supply is the power supply of operational amplifier.Select the lmr16006 power supply chip of ti company, its
Operation principle is buck reduction voltage circuit, carries out the setting of output voltage values, input voltage range by external reference resistance and exists
4v-60v, maximum output current is 1200ma.
DC voltage-stabilizing 65v power supply is the power supply of master controller, as the major power power supply of electrostimulator, by 24v
Total input power boosting obtains.Select the tps40210 booster power chip of ti company, its operation principle rises piezoelectricity for boost
Road, input voltage range 4.5v-52v, chip carries powerpad, has good heat dissipation characteristics, disclosure satisfy that functional electric
Stimulator system requirements.
Claims (10)
1. a kind of programmable functions electrostimulator with Real-time Feedback function is it is characterised in that described functional electric stimulation
Device includes master controller, power module and simulation constant current output module；
Master controller, according to the instruction of host computer, to simulation constant current output module output control signal, is additionally operable to permanent according to simulation
The electric current of stream output module output, revises to simulation constant current output module output control signal；
Simulation constant current output module, according to control signal, exports the electric current of respective waveforms；
Power module, is master controller and simulation constant current output module provides running voltage.
2. the programmable functions electrostimulator with Real-time Feedback function according to claim 1 is it is characterised in that institute
State master controller, according to the instruction of host computer, include to simulation constant current output module output control signal:
According to the instruction of host computer, carry out amplitude modulation, the control signal of output amplitude modulated sinusoid；
According to the instruction of host computer, carry out pulsewidth modulation, the control signal of output pulse width modulated sinusoid；
According to the instruction of host computer, export the control signal of accordingly free waveform.
3. the programmable functions electrostimulator with Real-time Feedback function according to claim 2 is it is characterised in that institute
State master controller, according to the instruction of host computer, carry out amplitude modulation, the control signal of output amplitude modulated sinusoid:
Receive basic waveform instruction and the amplitude modulation instruction that host computer sends；
According to the pulsewidth of basic waveform, frequency and amplitude, setting intervalometer and dac transducer in basic waveform instruction；According to work as
Front amplitude modulation instruction, is modulated, obtains modulation amplitude, according to the amplitude obtaining, changes dac transducer, according to timing
Device and dac transducer, the control signal of output amplitude modulated sinusoid.
4. the programmable functions electrostimulator with Real-time Feedback function according to claim 2 is it is characterised in that institute
State master controller, according to the instruction of host computer, carry out pulsewidth modulation, the control signal of output pulse width modulated sinusoid:
According to the pulsewidth of basic waveform, frequency and amplitude, setting intervalometer and dac transducer in basic waveform instruction；According to work as
Front pulsewidth modulation instruction, is modulated, and obtains modulation pulsewidth, according to the modulation pulsewidth obtaining, changes intervalometer, according to timing
Device and dac transducer, the control signal of output pulse width modulated sinusoid.
5. the programmable functions electrostimulator with Real-time Feedback function according to claim 2 is it is characterised in that institute
State master controller, according to the instruction of host computer, the control signal of the corresponding free waveform of output:
Receive the free waveform instruction of host computer；
Instructed according to free waveform, determine the waveform of control signal, control is determined according to the upper frequency sending free waveform instruction
The frequency of signal processed, according to the control signal of the waveform determining and the free waveform of rate-adaptive pacemaker.
6. the programmable functions electrostimulator with Real-time Feedback function according to claim 3,4 or 5, its feature exists
In, described master controller, it is additionally operable to the electric current according to simulation constant current output module output, to simulation constant current output module output control
Signal processed is:
According to the electric current of simulation constant current output module output, compared with default theoretical current, change control signal.
7. the programmable functions electrostimulator with Real-time Feedback function according to claim 6 it is characterised in that
Described controller, is additionally operable to determine whether excessively stream according to the electric current of simulation constant current output module output, when excessively stream occurs, to
Host computer sends alarm signal, controls power module to carry out power-off.
8. the programmable functions electrostimulator with Real-time Feedback function according to claim 7 is it is characterised in that institute
State controller, be additionally operable to determine whether excessively stream according to the electric current of simulation constant current output module output, when excessively stream occurs, to host computer
Send alarm signal, control power module to carry out power-off.
9. the programmable functions electrostimulator with Real-time Feedback function according to claim 8 is it is characterised in that institute
State simulation constant current output module and include operational amplifier u1a, n-channel mosfet pipe q1, resistance r1, resistance r2, resistance r3, resistance
R4, resistance r5, resistance r7, resistance r8, electric capacity c2, self- recoverage insurance f1 and controlled commutating circuit；
One end of resistance r3 is used for inputting the control signal of master controller, and the other end of resistance r3 is same with operational amplifier u1a's
Connect to signal input part, one end of resistance r5 is connected with the non-inverting signal input thereof of operational amplifier u1a, and resistance r5's is another
End is connected with one end of resistance r7, the source electrode of one end of electric capacity c2, one end of resistance r8 and n-channel mosfet pipe q1 simultaneously, electricity
The other end of the other end and resistance r8 that hold c2 connects simulation ground simultaneously；
Master controller obtains the electric current of simulation constant current output module output according to the other end of resistance r7；
The signal output part of operational amplifier u1a is connected with one end of resistance r4, and the other end of resistance r4 is managed with n-channel mosfet
The grid of q1 connects, and one end that the drain electrode of n-channel mosfet pipe q1 insures f1 with self- recoverage is connected, and self- recoverage insures the another of f1
End is connected with the outfan of controlled commutating circuit；
The sense of current control signal of master controller output inputs to controlled commutating circuit through resistance r1 or through resistance r2, controlled changes
Export to human body to after the electric current low-pass filtered device filtering of circuit output.
10. the programmable functions electrostimulator with Real-time Feedback function according to claim 9 it is characterised in that
Described controlled commutating circuit is the h bridge circuit realized using high pressure optocoupler.
Priority Applications (1)
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107080894A (en) * | 2017-05-05 | 2017-08-22 | 广州市第人民医院 | A kind of portable multichannel acupoint stimulation system |
| CN109316661A (en) * | 2017-07-31 | 2019-02-12 | 香港大学 | It is a kind of for the portable through cranium galvanic current stimulation system of pain therapy |
| CN109875553A (en) * | 2019-03-27 | 2019-06-14 | 北京脑陆科技有限公司 | A kind of extensive epilepsy automatic detection early warning based on EEG equipment and treatment intelligence system |
| CN109954209A (en) * | 2019-03-14 | 2019-07-02 | 北京京一合符医药科技发展有限公司 | A kind of high-voltage driving circuit system for functional electrostimulation |
| CN109976199A (en) * | 2017-12-27 | 2019-07-05 | 高权 | A kind of signal generation apparatus and the equipment with signal generation apparatus |
| CN111323637A (en) * | 2020-03-23 | 2020-06-23 | 乐普医学电子仪器股份有限公司 | Current pulse amplitude calibration method and automatic calibration acquisition circuit applied to DBS |
| CN112675430A (en) * | 2021-02-03 | 2021-04-20 | 杭州睿笛生物科技有限公司 | Closed-loop control median nerve stimulator and use method thereof |
| CN114326902A (en) * | 2021-12-31 | 2022-04-12 | 浙江浙大西投脑机智能科技有限公司 | Voltage wide-range adjustable current stimulation system for nerve regulation |
| CN115378250A (en) * | 2022-08-30 | 2022-11-22 | 济南大学 | Parameter-configurable multi-path bidirectional constant current source circuit and control method |
| WO2023142360A1 (en) * | 2022-01-27 | 2023-08-03 | 上海神奕医疗科技有限公司 | Constant-current source circuit, constant-current control method and directional electrical stimulation forming method and system |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20050046957A (en) * | 2003-11-15 | 2005-05-19 | 모승기 | Electrical therapy apparatus for performing function interlocking method using real-time feedback control loop |
| CN1745857A (en) * | 2005-10-28 | 2006-03-15 | 清华大学 | Implant nervous electric pulse stimulus system |
| CN102949781A (en) * | 2011-08-23 | 2013-03-06 | 郎国生 | Cerebral nerve pulse therapeutic device |
| CN103893914A (en) * | 2014-03-05 | 2014-07-02 | 复旦大学 | Program control multichannel electrophysiological stimulator |
| CN104027887A (en) * | 2014-06-30 | 2014-09-10 | 成都千里电子设备有限公司 | Power supply circuit suitable for medium-frequency electro-therapeutic instrument |
| CN104225790A (en) * | 2014-09-19 | 2014-12-24 | 清华大学 | Closed loop nerve stimulation system |
| CN204121597U (en) * | 2014-09-30 | 2015-01-28 | 华南理工大学 | A kind of portable electronic medical apparatus for treating menalgia |
| CN104740767A (en) * | 2015-04-16 | 2015-07-01 | 周基清 | Wearable and portable low-frequency pulse therapeutic device controlled by APP and application method of low-frequency pulse therapeutic device |
| CN104874102A (en) * | 2015-04-02 | 2015-09-02 | 中国科学院苏州生物医学工程技术研究所 | Multi-channel wireless closed loop deep brain neural sensing and control system |
| CN105536142A (en) * | 2016-01-22 | 2016-05-04 | 中国科学院微电子研究所 | Intelligent electric acupuncture apparatus |
-
2016
- 2016-08-23 CN CN201610710139.4A patent/CN106345054A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20050046957A (en) * | 2003-11-15 | 2005-05-19 | 모승기 | Electrical therapy apparatus for performing function interlocking method using real-time feedback control loop |
| CN1745857A (en) * | 2005-10-28 | 2006-03-15 | 清华大学 | Implant nervous electric pulse stimulus system |
| CN102949781A (en) * | 2011-08-23 | 2013-03-06 | 郎国生 | Cerebral nerve pulse therapeutic device |
| CN103893914A (en) * | 2014-03-05 | 2014-07-02 | 复旦大学 | Program control multichannel electrophysiological stimulator |
| CN104027887A (en) * | 2014-06-30 | 2014-09-10 | 成都千里电子设备有限公司 | Power supply circuit suitable for medium-frequency electro-therapeutic instrument |
| CN104225790A (en) * | 2014-09-19 | 2014-12-24 | 清华大学 | Closed loop nerve stimulation system |
| CN204121597U (en) * | 2014-09-30 | 2015-01-28 | 华南理工大学 | A kind of portable electronic medical apparatus for treating menalgia |
| CN104874102A (en) * | 2015-04-02 | 2015-09-02 | 中国科学院苏州生物医学工程技术研究所 | Multi-channel wireless closed loop deep brain neural sensing and control system |
| CN104740767A (en) * | 2015-04-16 | 2015-07-01 | 周基清 | Wearable and portable low-frequency pulse therapeutic device controlled by APP and application method of low-frequency pulse therapeutic device |
| CN105536142A (en) * | 2016-01-22 | 2016-05-04 | 中国科学院微电子研究所 | Intelligent electric acupuncture apparatus |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107080894A (en) * | 2017-05-05 | 2017-08-22 | 广州市第人民医院 | A kind of portable multichannel acupoint stimulation system |
| CN109316661A (en) * | 2017-07-31 | 2019-02-12 | 香港大学 | It is a kind of for the portable through cranium galvanic current stimulation system of pain therapy |
| CN109976199A (en) * | 2017-12-27 | 2019-07-05 | 高权 | A kind of signal generation apparatus and the equipment with signal generation apparatus |
| CN109976199B (en) * | 2017-12-27 | 2024-05-07 | 高权 | Signal generating device and equipment with same |
| CN109954209A (en) * | 2019-03-14 | 2019-07-02 | 北京京一合符医药科技发展有限公司 | A kind of high-voltage driving circuit system for functional electrostimulation |
| CN109954209B (en) * | 2019-03-14 | 2020-07-31 | 北京京一合符医药科技发展有限公司 | High-voltage driving circuit system for functional electrical stimulation |
| CN109875553A (en) * | 2019-03-27 | 2019-06-14 | 北京脑陆科技有限公司 | A kind of extensive epilepsy automatic detection early warning based on EEG equipment and treatment intelligence system |
| CN111323637A (en) * | 2020-03-23 | 2020-06-23 | 乐普医学电子仪器股份有限公司 | Current pulse amplitude calibration method and automatic calibration acquisition circuit applied to DBS |
| CN112675430A (en) * | 2021-02-03 | 2021-04-20 | 杭州睿笛生物科技有限公司 | Closed-loop control median nerve stimulator and use method thereof |
| CN114326902A (en) * | 2021-12-31 | 2022-04-12 | 浙江浙大西投脑机智能科技有限公司 | Voltage wide-range adjustable current stimulation system for nerve regulation |
| WO2023142360A1 (en) * | 2022-01-27 | 2023-08-03 | 上海神奕医疗科技有限公司 | Constant-current source circuit, constant-current control method and directional electrical stimulation forming method and system |
| CN115378250A (en) * | 2022-08-30 | 2022-11-22 | 济南大学 | Parameter-configurable multi-path bidirectional constant current source circuit and control method |
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