CN106310517B - Wearable brain function regulator control system - Google Patents
Wearable brain function regulator control system Download PDFInfo
- Publication number
- CN106310517B CN106310517B CN201610716300.9A CN201610716300A CN106310517B CN 106310517 B CN106310517 B CN 106310517B CN 201610716300 A CN201610716300 A CN 201610716300A CN 106310517 B CN106310517 B CN 106310517B
- Authority
- CN
- China
- Prior art keywords
- electrode
- wearable
- stimulation
- control system
- potential change
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36082—Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Radiology & Medical Imaging (AREA)
- Psychology (AREA)
- Biophysics (AREA)
- Developmental Disabilities (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Social Psychology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
A kind of wearable brain function regulator control system, comprising: multichannel brain electric recording electrode, galvanic current stimulation electrode, data acquisition and control module, wireless communication module, the wearable support device in head, cloud platform database and mobile terminal;Multichannel brain electric recording electrode acquires potential change signal from scalp;Galvanic current stimulation electrode stimulates scalp;Data acquisition and control module connecting multi-channel eeg recording electrode and galvanic current stimulation electrode, generate user's physiological status data according to potential change signal, module is exported to cloud platform database by wireless communication;Module receives the stimulation instructions that mobile terminal is sent by wireless communication, exports stimulated current to galvanic current stimulation electrode according to stimulation instructions;Cloud platform database purchase potential change signal and user's physiological status data;Mobile terminal analysis storage and display user's physiological status data, and export stimulation instructions.Regulator control system of the invention is easy to carry, and can give control accurate to brain activity state.
Description
Technical field
The present invention relates to electroencephalogram detection and brain function control techniques, and in particular, to a kind of wearable brain function tune
Control system.
Background technique
With the improvement of living condition, the sub-health state of body also increasingly causes to pay close attention to, insomnia, amnesia, attention
Not collecting the relevant sub-health state of medium brain function will affect normal work and life, and long-term sub-health state can be sent out
It transforms into as the cerebral function defects such as depression, schizophrenia and neurological disease.Including schizophrenia, senile dementia,
Cerebral function defect and neurological disease including epilepsy, depression, autism etc. seriously affect people's lives, and with society
Process that can be aging accelerates and the reasons such as environmental problem aggravation, the quantity of these patients is growing, with autism
(Autism) for, by the end of 2014, data were shown, just there is 1 autism spectrum disorder, and boy in every 68 children
(disease incidence: 1/42) than girl, (disease incidence: 1/189) height, male to female ratio, in China, push away between 4:1 to 5:1 when disease incidence
It surveys self-closing disease patient and reaches 10,000,000, this brings great financial burden to family, society.
Caused by mental disease or brain function inferior health are intrinsically the exception due to cerebral nerve loop.Brain
It is an organ by being formed at hundred billion neurons, these neurons form a neural network being interweaved, nerve net
The transmitting and integration of information are carried out between network by the film potential granting of neuron, therefore, the exception of neural circuitry can also recognize
For the disorder for being cerebral nerve network electrical activity.In order to regulate and control to the neural circuitry of electrical activity disorder, scientist utilizes light
Hereditary (Optogenetics) technology, expressed photaesthesia albumen color neuron for the light stimulus of specific wavelength in advance, can make
The ion channel activation of neuron or closing influence small white mouse with this method to regulate and control the electrical activity of neural circuitry
Brain, allow the small white mouse with parkinsonism to stand up again, even walk again.
Although light genetic technique mentioned above can precisely arrive individual cells and carry out neururgic regulation, thing is needed
First expression virus, and need to be implanted into optical fiber, this is restricted application of the light genetic technique on human body.Currently, can
Include nature stimulation, pharmaceutical intervention, electricity, magnetic, power stimulation etc. with the technology regulated and controled for neural circuitry, is inherently to change mind
Electrical activity through network.Among this, stimulation is easiest to receive patient naturally, few side effect, but has little effect;Drug is dry
It is pre- most widely used, but its mode for influencing neural circuitry is indirect, and larger with side effect;Electricity, magnetic, power stimulation are made
With more directly, stimulates and intervene especially by the application of external non-intrusion type, can reduce the pain of patient.
Currently, noninvasive through cranium galvanic current stimulation (transcranial Direct Current Stimulation, tDCS)
In conjunction with neuroimaging such as functional mri (fMRI), (PET) is imaged in position emissron tomography, electroencephalogram (EEG), brain
The development of magnetic chart (MEG), allows electro photoluminescence combination brain function neural analysis simple before, and tDCS also becomes cognition neural
Science, brain science research, one of the main means of mental disease treatment.Clinically, EEG and tDCS is combined, can be used for changing
Kind sleep quality analyzes sleep stage locating for user while real-time monitoring user EEG, when detecting that user is in deep
When spending sleep state, apply faint galvanic current stimulation using tDCS stimulator, so that the slow wave brain wave in θ and δ frequency band increases,
To achieve the effect that improve sleep quality.
The method and apparatus clinically used is more professional, but equipment is expensive, and not readily portable, cannot achieve household.
With the development of technology, there is more and more wearable portable obtain for brain EEG signal or neural circuitry
Electro photoluminescence adjusting device.Such as: the application publication number of U.S. Sai Enke is to be related to one in the Chinese patent of CN 105457158A
The wearable transcutaneous nerve stimulator of kind, equipment is light wearable, and is configured to be worn on the temple of subject, and with
Electrode combination, which combines, is securely and comfortably suitable for different head sizes.These equipment may be configured to which kind of is uniquely identified
Electrode has been coupled to nerve electric stimulation device, and be configured to transmission may the synthetic waveform containing capacitive discharge component to enhance
The comfort of user.
In the patent of invention of the application publication number CN 105492067A of HaloNeuro company, introduce a kind of for electro photoluminescence
The system of user and/or detection bioelectrical signals from the user, which includes: infiltration volume array, is electrically coupled solution, shell
Deng.The system mainly solves insufficient contact between the electrode (multiple) including study subject and system, in study subject
It is steadily contacted very much between the electrode of system.
Application publication number is the Chinese patent of CN 102512159B, describes a kind of Portable wireless electroencephalogramacquisition acquisition device,
Including the multiple scalp electrodes for eeg signal acquisition being connected with brain wave acquisition module input, scalp electrode output end with
EEG signals extraction module is connected, logical through EEG signals extraction module treated EEG signals input EEG Processing module
It crosses and is transmitted wire-lessly to EEG signals receiving end.The volume of traditional eeg collection system front-end circuit is reduced, thus is had
Good portability, the mode of wireless transmission relieve wired eeg collection system to the limitation on subject spatial position.
In the professional brain wave acquisition equipment and tDCS stimulator that use clinically mentioned above, although having fine
Using effect, but can what is considered when purchasing equipment due to hospital be have multi-functional, in multiple departments, is directed to a variety of
Diagnosis, treatment can use, and for the volume of equipment, the cost consideration of the complexity of operation, equipment is less.Therefore, it is in
With in environment, just in the more single usage scenario of user, equipment of these professions cannot achieve portable operation, and at
Originally it is difficult to bear.
The application publication number of U.S. Sai Enke is the Chinese patent of 105457158 A of CN and the application of HaloNeuro company
In the patent of invention of 105492067 A of publication No. CN, although having good portability and comfort, it can only realize
One-side nerve electric stimulation, but the current active state of brain can not be obtained.The active state of brain be it is fast changing, only
Have and know current active state, could targetedly adjust stimulation parameter, gives optimal stimulation.
Application publication number is to reduce traditional eeg collection system front-end circuit in the Chinese patent of 102512159 B of CN
Volume, be capable of the acquisition EEG signals of portable wireless, and then by analyzing the current nervous activity section of available brain
Rule and cognitive state.But it can only also realize one-side signal-obtaining, stimulation regulation can not be applied.
Summary of the invention
The present invention provides a kind of wearable brain function regulator control system, to touch while carrying out potential change signal acquisition
The galvanic current stimulation for sending out faint accurately regulates and controls for specific brain activity state.
To achieve the goals above, the present invention provides a kind of wearable brain function regulator control system, the wearable brain function
Energy regulator control system includes: multichannel brain electric recording electrode, galvanic current stimulation electrode, data acquisition and control module, wireless communication
Module, the wearable support device in head, cloud platform database and mobile terminal;The eeg recording electrode, galvanic current stimulation electricity
Pole, data acquisition are set in the wearable support device in the head with control module and wireless communication module;
The multiple electrodes of the multichannel brain electric recording electrode are distributed in the different zones of scalp respectively, for adopting from scalp
Collect current potential variable signal;
The galvanic current stimulation electrode is for stimulating the scalp;
The data acquisition connect the multichannel brain electric recording electrode and galvanic current stimulation electrode, a side with control module
Face receives the potential change signal of the multichannel brain electric recording electrode acquisition, and it is raw to generate user according to the potential change signal
Status data is managed, and is exported by the wireless communication module to the cloud platform database;On the other hand by described wireless
Communication module receives the stimulation instructions that the mobile terminal is sent, defeated to the galvanic current stimulation electrode according to the stimulation instructions
Stimulated current out, to trigger galvanic current stimulation while acquiring potential change signal;
The cloud platform database is for storing the potential change signal and user's physiological status data;
The mobile terminal connects the cloud platform database, for analyzing storage and showing user's physiological status number
According to, and export the stimulation instructions.
In one embodiment, the data acquisition includes: with control module
Electroencephalogram Acquisition Circuit receives the potential change signal of the multichannel brain electric recording electrode transmission, to the electricity
Position variable signal amplifies, filter and analog-to-digital conversion after generate user's physiological status data and export;
Microcontroller connects the electroencephalogram Acquisition Circuit, receives at user's physiological status data and by described
Wireless communication module output, and receive the stimulation instructions of the mobile terminal;
Galvanic current stimulation circuit connects the microcontroller, generates stimulation after carrying out digital-to-analogue conversion to the stimulation instructions
Electric current, and the stimulated current is exported to the galvanic current stimulation electrode.
In one embodiment, the electroencephalogram Acquisition Circuit includes:
Signal amplification circuit amplifies processing to the potential change signal;
Analogue filter circuit connects the signal amplification circuit, is filtered to the potential change signal after enhanced processing
Processing;
Analog-digital converter connects the analogue filter circuit, and the potential change signal after filtering processing is converted to number
Signal simultaneously exports.
In one embodiment, the galvanic current stimulation circuit includes:
Digital analog converter connects the microcontroller, for the stimulation instructions to be converted to analog signal;
Micro-current control unit connects the digital analog converter, for generating the stimulation electricity according to the analog signal
Stream;
Pulse output unit connects the micro-current control unit, for exporting the stimulated current to the direct current
Electric stimulation electrode.
In one embodiment, the wearable support device in head includes:
The head of annular support part, inner surface and user fit;
An at least lug boss is arranged above the annular support part, fits at the top of inner surface and the head;
The lower section of the annular support part is arranged in circuit board fixed part, for carrying the data acquisition and control mould
Block and wireless communication module.
In one embodiment, the multiple electrodes of the multichannel brain electric recording electrode are uniformly arranged on the annular support part
Inner surface.
In one embodiment, the galvanic current stimulation electrode is disposed therein the inner surface of a lug boss.
In one embodiment, the galvanic current stimulation electrode includes an anode and four cathodes, and four cathodes are located at
On one round circumference, the anode is located at the center of the circle.
In one embodiment, the wearable brain function regulator control system further include: reference electrode is attached to user's ear-lobe position,
And the signal amplification circuit is connected, the reference as the multichannel brain electric recording electrode.
In one embodiment, the wearable brain function regulator control system further include: power supply module, setting are solid in the circuit board
Determine in portion, for data acquisition and control module and wireless communication module power supply.
The beneficial effect of the embodiment of the present invention is, utilizes wearable brain function regulator control system of the invention, Ke Yi
It carries out triggering faint galvanic current stimulation while potential change signal acquisition, give accurately for specific brain activity state
Regulation.And wearable brain function regulator control system of the invention is easy to carry.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with
It obtains other drawings based on these drawings.
Fig. 1 is the structural schematic diagram of the wearable brain function regulator control system of the embodiment of the present invention;
Fig. 2 is the structural schematic diagram of the wearable support device in head of the embodiment of the present invention;
Fig. 3 is the multichannel brain electric recording electrode some of the embodiment of the present invention according to position view;
Fig. 4 is the structural schematic diagram of the data acquisition and control module of one embodiment of the invention;
Fig. 5 is the structural schematic diagram of the data acquisition and control module of another embodiment of the present invention;
Fig. 6 A is the software main interface schematic diagram of the embodiment of the present invention;
Fig. 6 B is that schematic diagram is arranged in the system of the embodiment of the present invention;
Fig. 6 C is the interface schematic diagram that the EEG data of the embodiment of the present invention is shown;
Fig. 6 D is the parameters of electrical stimulation set interface schematic diagram of the embodiment of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Fig. 1 is the structural schematic diagram of the wearable brain function regulator control system of the embodiment of the present invention, as shown in Figure 1, this can
Wearable brain function controlling system includes: multichannel brain electric recording electrode 101, galvanic current stimulation electrode 102, data acquisition and control
Molding block 103, wireless communication module 104, the wearable support device 106 in head, cloud platform database 107 and mobile terminal 108.
Wherein, eeg recording electrode 101, galvanic current stimulation electrode 102, data acquisition and control module 103 and channel radio
Letter module 104 is set in the wearable support device 106 in head.
The multiple electrodes of multichannel brain electric recording electrode 101 are distributed in the different zones of scalp respectively, for adopting from scalp
Collect current potential variable signal;
Galvanic current stimulation electrode 102 for stimulating scalp, the material of galvanic current stimulation electrode 102 can be Ag,
One kind of the materials such as AgCl, stainless steel, gold.
Data acquisition and 103 connecting multi-channel eeg recording electrode of control module and galvanic current stimulation electrode, on the one hand connect
The potential change signal that multichannel brain electric recording electrode 101 acquires is received, user's physiological status number is generated according to potential change signal
According to, and module 104 is exported to cloud platform database 107 by wireless communication;On the other hand module 105 receives by wireless communication
Mobile terminal 108 passes through the stimulation instructions sent of cloud platform database 107, according to stimulation instructions to galvanic current stimulation electrode 102
Stimulated current is exported, to trigger galvanic current stimulation while acquiring potential change signal.
In one embodiment, wireless communication module 104 includes low-power consumption bluetooth communication module and Wi-Fi communication module.One is real
It applies in example, Bluetooth communication uses the CC2540 low-power consumption bluetooth SoC of TI company, is based on 4.0 core specification of bluetooth, adopts
With the short-distance wireless communication technology of 2.4GHz, the mobile devices such as IOS, Android are supported extensively, and there is very low function
Consumption realizes that primary charging is able to use the long period.In Wi-Fi communication, using TI CC3200 low-power consumption Wi-Fi communication chip,
The safe encryption mode of WEP WPA/WPA2 is supported to send data to platform data via router by onboard antenna
Library.
Module 105 is connected to data acquisition and control module 103 to cloud platform database 107 by wireless communication, for depositing
Storage position variable signal and user's physiological status data are used for hospital, scientific research institution etc. by the access of interconnection web form.
Mobile terminal 108 connects cloud platform database 107, for analyzing storage and display user's physiological status data, and
Export stimulation instructions.Mobile terminal 108 can be the mobile devices such as mobile phone, tablet computer.
The structure of the wearable support device 106 in head is as shown in Figure 2, comprising: annular support part 201, lug boss 207 and electricity
Road plate fixed part 206.
In one embodiment, the wearable support device 106 in head is made of TPE-X material, and this material has comfortable touching
Sense, soft hardness.The wearable support device 106 in head can make for multichannel brain electric recording electrode 101 (EEG electrode) to be close to
In the surface of scalp, and it is unlikely to the constriction for having too strong.
As shown in Fig. 2, annular support part 201 is designed according to user's head profile, the inner surface and use of annular support part 201
The head at family fits.A portion electrode of multichannel brain electric recording electrode is uniformly arranged on the interior of the annular support part
Surface, such as 203 positions in Fig. 2.The electrode material of multichannel brain electric recording electrode can be Ag, AgCl, stainless steel, Jin Dengcai
One kind of material can be directly connected to the stem grafting contact of scalp, not need to smear conducting resinl on scalp.
Lug boss 207 is arranged above the annular support part, fits at the top of inner surface and the head.Multi-pass
The inner surface in lug boss 207 can be set in the remainder electrode of road eeg recording electrode.Galvanic current stimulation electrode is set to
The inner surface of one of lug boss, galvanic current stimulation electrode include an anode and four cathodes, wherein four cathodes are located at
On one round circumference, anode is located at the center of the circle, as shown in the position of 204 marks in Fig. 2.
In one embodiment, multichannel brain electric recording electrode has 16, according to the 10-20 lead method of international standard, is distributed in
The position of scalp, as shown in Figure 3.
The lower section of annular support part is arranged in circuit board fixed part 206, by the shell packet of the wearable support device 106 in head
It is wrapped in wherein, so that circuit board fixed part 206 is not exposed to outside, for carrying data acquisition and control module 103 and channel radio
Believe module 104.
In one embodiment, the wearable brain function regulator control system of the embodiment of the present invention further include: power supply module 105, if
It sets on circuit board fixed part, can power for data acquisition with control module 103 and wireless communication module 104.Power supply module
105 can be rechargeable battery or radio frequency powered device, and rechargeable battery is lithium ion battery or lithium polymer battery, and head can
Wearing support device one of is produced electricl energy as being incuded by coil in vivo, can be entirely to wear
The DC voltage of device offer 3.3V.
In one embodiment, the wearable brain function regulator control system of the embodiment of the present invention further include: reference electrode is attached to use
Family ear-lobe position, and connection signal amplifying circuit, the reference as the multichannel brain electric recording electrode.
In one embodiment, as shown in figure 4, data acquisition and control module 103 include: electroencephalogram Acquisition Circuit, microcontroller
Device and galvanic current stimulation circuit.
Electroencephalogram Acquisition Circuit can receive the potential change signal of multichannel brain electric recording electrode transmission, to potential change
Signal amplifies, filter and analog-to-digital conversion after generate user's physiological status data and export to microcontroller;
Microcontroller connects electroencephalogram Acquisition Circuit, receives into user's physiological status data and module is defeated by wireless communication
Out to cloud platform database 107 and mobile terminal 108, and receive the stimulation instructions of mobile terminal 108.
Galvanic current stimulation circuit connection microcontroller generates stimulated current after carrying out digital-to-analogue conversion to stimulation instructions, and will
The stimulated current is exported to galvanic current stimulation electrode.
When it is implemented, as shown in figure 5, electroencephalogram Acquisition Circuit shown in Fig. 4 includes: signal amplification circuit, simulation filter
Wave circuit and analog-digital converter.
Signal amplification circuit, the multiple electrodes of connecting multi-channel eeg recording electrode 101, to the potential change of each electrode
Signal amplifies processing;
Analogue filter circuit connects the signal amplification circuit, is filtered to the potential change signal after enhanced processing
Processing, filters out interference signal therein.
Analog-digital converter connects the analogue filter circuit, and the potential change signal after filtering processing is converted to number
Signal simultaneously exports.
Galvanic current stimulation circuit shown in Fig. 4 includes: digital analog converter, micro-current control unit and pulse output unit.
Digital analog converter connects microcontroller, for the stimulation instructions to be converted to analog signal;Micro-current control is single
Member connects the digital analog converter, for generating the stimulated current according to the analog signal;Pulse output unit connects institute
Micro-current control unit is stated, for exporting stimulated current to the galvanic current stimulation electrode.
Processing intermediary of the microcontroller as input and output is controlled and is entirely worn using the MCU of STM32F103 model
Modules on device.In one embodiment, the important technological parameters of data acquisition and control module 103 are as follows: sample rate
1000Hz, 16 channel of port number, input range ± 15mV.
The present invention is when it is implemented, cloud platform database 107 is put down using MySQL foundation as third-party cloud is stored in
Platform supplier, such as Amazon Ali's cloud etc..By the original signal of acquisition and the user analyzed in cloud platform database 107
Physiological status data stores, and can be convenient user and accesses the data of oneself in the case where accessing internet, while passing through
In the case that user permits, used by the way that API is open to other users or mechanism.
108 mobile terminal softwares, including being run on mobile phone, tablet computer with data record, visualization display, being divided
The software of the functions such as analysis, storage, the platform of operation can be the Mobile operating platforms such as IOS, Android, WindowsPhone.Figure
6A to Fig. 6 D is 4 major design figures of mobile terminal software, and Fig. 6 A is the software main interface schematic diagram of the embodiment of the present invention, figure
6B is that schematic diagram is arranged in the system of the embodiment of the present invention, and Fig. 6 C is the interface schematic diagram that the EEG data of the embodiment of the present invention is shown,
Fig. 6 D is the parameters of electrical stimulation set interface schematic diagram of the embodiment of the present invention.Wherein, in Fig. 6 A, there are mainly three types of manipulation choosings by user
Select: the EEG data into Fig. 6 C checks interface, and boundary is arranged in the system of parameters of electrical stimulation set interface and Fig. 6 B into Fig. 6 D
Face.In the system set interface of Fig. 6 B, including bluetooth state switch, device name, data save switch, user's logging state
Button.It is checked in interface in Fig. 6 C EEG data, can check the EEG time-domain signal variation in multiple channels simultaneously, can also look into
See the distribution current by each frequency band of frequency-domain transform, these frequency bands include δ (1-3Hz, sleep state), θ (4-7Hz,
The states such as loosen, think deeply), Low α (8-9Hz is closed one's eyes, loosened), High α (10-12Hz), β (13-30Hz), γ (31-50Hz)
Deng.In the parameters of electrical stimulation set interface of Fig. 6 D, current strength, stimulation time, frequency of stimulation can be adjusted by dragging item
Etc. parameters.
Using wearable brain function regulator control system of the invention, can be touched while carrying out potential change signal acquisition
The galvanic current stimulation for sending out faint accurately regulates and controls for specific brain activity state.And wearable brain of the invention
Function controlling system is easy to carry.
It should be understood by those skilled in the art that, the embodiment of the present invention can provide as method, system or computer program
Product.Therefore, complete hardware embodiment, complete software embodiment or reality combining software and hardware aspects can be used in the present invention
Apply the form of example.Moreover, it wherein includes the computer of computer usable program code that the present invention, which can be used in one or more,
The computer program implemented in usable storage medium (including but not limited to magnetic disk storage, CD-ROM, optical memory etc.) produces
The form of product.
The present invention be referring to according to the method for the embodiment of the present invention, the process of equipment (system) and computer program product
Figure and/or block diagram describe.It should be understood that every one stream in flowchart and/or the block diagram can be realized by computer program instructions
The combination of process and/or box in journey and/or box and flowchart and/or the block diagram.It can provide these computer programs
Instruct the processor of general purpose computer, special purpose computer, Embedded Processor or other programmable data processing devices to produce
A raw machine, so that being generated by the instruction that computer or the processor of other programmable data processing devices execute for real
The device for the function of being specified in present one or more flows of the flowchart and/or one or more blocks of the block diagram.
These computer program instructions, which may also be stored in, is able to guide computer or other programmable data processing devices with spy
Determine in the computer-readable memory that mode works, so that it includes referring to that instruction stored in the computer readable memory, which generates,
Enable the manufacture of device, the command device realize in one box of one or more flows of the flowchart and/or block diagram or
The function of being specified in multiple boxes.
These computer program instructions also can be loaded onto a computer or other programmable data processing device, so that counting
Series of operation steps are executed on calculation machine or other programmable devices to generate computer implemented processing, thus in computer or
The instruction executed on other programmable devices is provided for realizing in one or more flows of the flowchart and/or block diagram one
The step of function of being specified in a box or multiple boxes.
Specific embodiment is applied in the present invention, and principle and implementation of the present invention are described, above embodiments
Explanation be merely used to help understand method and its core concept of the invention;At the same time, for those skilled in the art,
According to the thought of the present invention, there will be changes in the specific implementation manner and application range, in conclusion in this specification
Appearance should not be construed as limiting the invention.
Claims (10)
1. a kind of wearable brain function regulator control system characterized by comprising multichannel brain electric recording electrode, direct current thorn
Swash electrode, data acquisition and control module, wireless communication module, the wearable support device in head, cloud platform database and movement
Terminal;The eeg recording electrode, galvanic current stimulation electrode, data acquisition are set to institute with control module and wireless communication module
It states in the wearable support device in head;
The multiple electrodes of the multichannel brain electric recording electrode are distributed in the different zones of scalp respectively, for acquiring electricity from scalp
Position variable signal;
The galvanic current stimulation electrode is for stimulating the scalp;
The data acquisition connect the multichannel brain electric recording electrode and galvanic current stimulation electrode with control module, on the one hand connects
The potential change signal for receiving the multichannel brain electric recording electrode acquisition, generates user's physiology shape according to the potential change signal
State data, and exported by the wireless communication module to the cloud platform database;On the other hand pass through the wireless communication
Module receives the stimulation instructions that the mobile terminal is sent, and is exported and is pierced to the galvanic current stimulation electrode according to the stimulation instructions
Electric current is swashed, to trigger galvanic current stimulation while acquiring potential change signal;
The cloud platform database is for storing the potential change signal and user's physiological status data;
The mobile terminal connects the cloud platform database, for analyzing storage and showing user's physiological status data,
And export the stimulation instructions;
The wearable support device in head includes:
The head of annular support part, inner surface and user fit;
Multiple lug bosses above the annular support part, and the top of the inner surface of the lug boss and the head are set
It fits, the partial electrode and galvanic current stimulation electrode in multichannel brain electric recording electrode are arranged at the interior table of the lug boss
Face.
2. wearable brain function regulator control system according to claim 1, which is characterized in that the data acquisition and control
Module includes:
Electroencephalogram Acquisition Circuit receives the potential change signal of the multichannel brain electric recording electrode transmission, becomes to the current potential
Change signal amplify, filter and analog-to-digital conversion after generate user's physiological status data and export;
Microcontroller connects the electroencephalogram Acquisition Circuit, receives at user's physiological status data and by described wireless
Communication module output, and receive the stimulation instructions of the mobile terminal;
Galvanic current stimulation circuit connects the microcontroller, generates stimulated current after carrying out digital-to-analogue conversion to the stimulation instructions,
And the stimulated current is exported to the galvanic current stimulation electrode.
3. wearable brain function regulator control system according to claim 2, which is characterized in that the electroencephalogram Acquisition Circuit
Include:
Signal amplification circuit amplifies processing to the potential change signal;
Analogue filter circuit connects the signal amplification circuit, is filtered to the potential change signal after enhanced processing;
Analog-digital converter connects the analogue filter circuit, and the potential change signal after filtering processing is converted to digital signal
And it exports.
4. wearable brain function regulator control system according to claim 2, which is characterized in that the galvanic current stimulation circuit
Include:
Digital analog converter connects the microcontroller, for the stimulation instructions to be converted to analog signal;
Micro-current control unit connects the digital analog converter, for generating the stimulated current according to the analog signal;
Pulse output unit connects the micro-current control unit, pierces for exporting the stimulated current to the direct current
Swash electrode.
5. wearable brain function regulator control system according to claim 1, which is characterized in that the wearable support in head
Device further include:
The lower section of the annular support part is arranged in circuit board fixed part, for carry data acquisition and control module and
Wireless communication module.
6. wearable brain function regulator control system according to claim 5, which is characterized in that the multichannel brain electrographic recording
The multiple electrodes of electrode are uniformly arranged on the inner surface of the annular support part.
7. wearable brain function regulator control system according to claim 1, which is characterized in that the galvanic current stimulation electrode
Including an anode and four cathodes, four cathodes are located on a round circumference, and the anode is located in the circle
The heart.
8. wearable brain function regulator control system according to claim 3, which is characterized in that further include: reference electrode, patch
In user's ear-lobe position, and the signal amplification circuit is connected, the reference as the multichannel brain electric recording electrode.
9. wearable brain function regulator control system according to claim 5, which is characterized in that further include: power supply module, if
It sets on the circuit board fixed part, for data acquisition and control module and wireless communication module power supply.
10. wearable brain function regulator control system according to claim 5, which is characterized in that the wearable branch in head
Support arrangement further include: telescopic adjustment button is arranged on the annular support part, for adjusting the ring according to user's head size
Shape support portion.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610716300.9A CN106310517B (en) | 2016-08-24 | 2016-08-24 | Wearable brain function regulator control system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610716300.9A CN106310517B (en) | 2016-08-24 | 2016-08-24 | Wearable brain function regulator control system |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106310517A CN106310517A (en) | 2017-01-11 |
CN106310517B true CN106310517B (en) | 2019-09-27 |
Family
ID=57791213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610716300.9A Active CN106310517B (en) | 2016-08-24 | 2016-08-24 | Wearable brain function regulator control system |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106310517B (en) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106890396A (en) * | 2017-02-28 | 2017-06-27 | 深圳先进技术研究院 | A kind of negative-morality adjusting method and device for shaking electric current at random based on high frequency |
CN107019844A (en) * | 2017-02-28 | 2017-08-08 | 深圳先进技术研究院 | It is a kind of to be used to regulate and control method and its device that the concussion electric current of brain is produced |
CN107137078A (en) * | 2017-05-08 | 2017-09-08 | 京东方科技集团股份有限公司 | Brain wave detection device and equipment |
CN107174240A (en) * | 2017-06-02 | 2017-09-19 | 江苏博恩医疗科技有限公司 | A kind of portable multi-lead Electrodo cap for electroencephalogram |
CN107281635B (en) * | 2017-07-26 | 2024-01-16 | 江苏海莱新创医疗科技有限公司 | Electrode physiotherapy device and electrode positioning method |
CN108065932A (en) * | 2017-09-13 | 2018-05-25 | 中科搏锐(北京)科技有限公司 | Brain function activity detects and regulation and control integrated processes, apparatus and system |
CN107951486A (en) * | 2017-12-04 | 2018-04-24 | 深圳贝特莱电子科技股份有限公司 | A kind of dry electrode eeg signal acquisition device of wear-type |
CN108187226B (en) * | 2017-12-14 | 2022-06-17 | 深圳华蘅科技有限公司 | Stimulation system |
CN109925601A (en) * | 2017-12-18 | 2019-06-25 | 航天信息股份有限公司 | A kind of head-mount device |
CN108365647A (en) * | 2018-02-11 | 2018-08-03 | 广东欧珀移动通信有限公司 | Control charge mode method and relevant apparatus |
FR3077723B1 (en) * | 2018-02-15 | 2020-03-13 | Centre National De La Recherche Scientifique | PORTABLE ELECTROENCEPHALOGRAPHERS |
CN108607159A (en) * | 2018-03-21 | 2018-10-02 | 重庆邮电大学 | A kind of DBS system acquiring LFP data |
CN108498094B (en) * | 2018-03-29 | 2021-06-01 | Oppo广东移动通信有限公司 | Brain wave information transmission control method and related product |
CN108670275A (en) * | 2018-05-22 | 2018-10-19 | Oppo广东移动通信有限公司 | Signal processing method and related product |
CN109260591B (en) * | 2018-08-02 | 2022-08-19 | 深圳英智科技有限公司 | Transcranial stimulation method and device |
CN109199371A (en) * | 2018-09-29 | 2019-01-15 | 北京机械设备研究所 | A kind of wearable brain electricity acquisition device |
CN109800626A (en) * | 2018-11-28 | 2019-05-24 | 东莞理工学院 | A kind of acquiring brain waves analysis system and electric platforms control system and control method |
CN109308085B (en) * | 2018-12-13 | 2023-06-09 | 贝乐(广州)智能信息科技有限公司 | Wearable equipment control circuit and wearable equipment |
GB2579827A (en) * | 2018-12-14 | 2020-07-08 | Brainpatch Ltd | Brain interfacing apparatus and method |
CN109876292A (en) * | 2019-03-01 | 2019-06-14 | 上海库石医疗技术有限公司 | Micro-current electrotherapy circuit |
CN110368577A (en) * | 2019-07-03 | 2019-10-25 | 天津大学 | Programmable flexibility electrical transcranial stimulation and brain wave acquisition integrated system |
CN110403603B (en) * | 2019-08-07 | 2023-06-23 | 龙岩学院 | Monitoring equipment for assisting epileptic surgery |
CN110477917A (en) * | 2019-08-13 | 2019-11-22 | 深圳先进技术研究院 | Intracerebral lymphatic vessel stimulating system, method and control device |
CN110742604B (en) * | 2019-09-20 | 2022-04-01 | 复旦大学附属华山医院 | Cortical electroencephalogram-based brain function positioning method under electrical stimulation of median nerve |
CN110721401A (en) * | 2019-11-28 | 2020-01-24 | 中国科学院深圳先进技术研究院 | Neural regulation and control system and wearable neural regulation and control device |
CN111588630B (en) * | 2020-05-27 | 2022-07-12 | 深圳市安瑞国医科技有限公司 | Percutaneous nerve regulation and control strategy generation method and device |
CN111973880A (en) * | 2020-06-11 | 2020-11-24 | 天津工业大学 | Mental fatigue intervention equipment and intervention method |
CN111921101A (en) * | 2020-07-10 | 2020-11-13 | 深圳先进技术研究院 | Head-mounted ultrasonic nerve stimulation device and system |
CN112402792A (en) * | 2020-11-04 | 2021-02-26 | 深圳中科华意科技有限公司 | Nerve regulation and control device and method |
CN112402791A (en) * | 2020-11-04 | 2021-02-26 | 深圳中科华意科技有限公司 | Nerve regulation and control device and method |
CN112353396B (en) * | 2020-11-09 | 2023-10-13 | 北京大学深圳研究生院 | Health monitoring system based on human body surface electric signals |
CN113180702A (en) * | 2021-04-07 | 2021-07-30 | 北京脑陆科技有限公司 | Alzheimer's disease nerve regulation and control method and system based on EEG signal |
CN115120873B (en) * | 2022-08-30 | 2023-05-09 | 首都医科大学宣武医院 | Helmet type closed loop rhythmicity regulator |
CN115568865B (en) * | 2022-10-18 | 2024-07-23 | 天津大学 | Multichannel brain response identification system based on brain electrical data driving |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8498717B2 (en) * | 2007-05-14 | 2013-07-30 | Gachon University Of Medicine & Science Industry-Academic Cooperation Foundation | Neural electronic interface device for motor and sensory controls of human body |
CN204411500U (en) * | 2014-12-23 | 2015-06-24 | 先進電子醫療工業有限公司 | Wear-type controlled in wireless electrical transcranial stimulation instrument |
CN104825153A (en) * | 2015-01-07 | 2015-08-12 | 湘潭大学 | Remote wearable synchronous detection system for multiplex medical electric signals based on cloud computing |
CN104922795A (en) * | 2015-05-27 | 2015-09-23 | 上海诺之嘉医疗器械有限公司 | Insomnia therapeutic method based on Android system |
CN204709648U (en) * | 2015-04-02 | 2015-10-21 | 中国科学院苏州生物医学工程技术研究所 | A kind of channel wireless radio multi closed loop brain deep nerve regulator control system |
CN206492111U (en) * | 2016-08-24 | 2017-09-15 | 中国科学院深圳先进技术研究院 | Wearable brain function regulator control system |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2015016183A (en) * | 2013-07-12 | 2015-01-29 | 鄭智隆 | Method for using brain part health management cap |
JP6720146B2 (en) * | 2014-09-17 | 2020-07-08 | ネウロリーフ リミテッド | Headset for nerve stimulation and sensing of physical parameters |
-
2016
- 2016-08-24 CN CN201610716300.9A patent/CN106310517B/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8498717B2 (en) * | 2007-05-14 | 2013-07-30 | Gachon University Of Medicine & Science Industry-Academic Cooperation Foundation | Neural electronic interface device for motor and sensory controls of human body |
CN204411500U (en) * | 2014-12-23 | 2015-06-24 | 先進電子醫療工業有限公司 | Wear-type controlled in wireless electrical transcranial stimulation instrument |
CN104825153A (en) * | 2015-01-07 | 2015-08-12 | 湘潭大学 | Remote wearable synchronous detection system for multiplex medical electric signals based on cloud computing |
CN204709648U (en) * | 2015-04-02 | 2015-10-21 | 中国科学院苏州生物医学工程技术研究所 | A kind of channel wireless radio multi closed loop brain deep nerve regulator control system |
CN104922795A (en) * | 2015-05-27 | 2015-09-23 | 上海诺之嘉医疗器械有限公司 | Insomnia therapeutic method based on Android system |
CN206492111U (en) * | 2016-08-24 | 2017-09-15 | 中国科学院深圳先进技术研究院 | Wearable brain function regulator control system |
Also Published As
Publication number | Publication date |
---|---|
CN106310517A (en) | 2017-01-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN106310517B (en) | Wearable brain function regulator control system | |
WO2021203719A1 (en) | Acoustic-electric stimulation neuromodulation therapy and apparatus combining electroencephalogram testing, analysis and control | |
KR102680648B1 (en) | Multifunctional closed loop neuro feedback stimulating device and methods thereof | |
CN107463792B (en) | Nerve feedback device, system and method | |
CN207071165U (en) | A kind of Intelligent Composite waveform electrical transcranial stimulation system | |
Lin et al. | An ultra-low power smart headband for real-time epileptic seizure detection | |
CN107684664A (en) | A kind of Intelligent Composite waveform electrical transcranial stimulation system | |
US20150105837A1 (en) | Brain therapy system and method using noninvasive brain stimulation | |
CN106377252A (en) | Biologic information feedback system based on virtual reality | |
US20170007173A1 (en) | System for polyphasic sleep management, method of its operation, device for sleep analysis, method of current sleep phase classification and use of the system and the device in polyphasic sleep management | |
CN112402792A (en) | Nerve regulation and control device and method | |
CN206492111U (en) | Wearable brain function regulator control system | |
JP3217412U (en) | Smart composite waveform transcranial electrical stimulation system | |
Zhan et al. | A resource-optimized VLSI implementation of a patient-specific seizure detection algorithm on a custom-made 2.2 cm $^ 2$ wireless device for ambulatory epilepsy diagnostics | |
CN106725455A (en) | It is used for the training system and method for brain ability training based on sensor feedback | |
CN105342606A (en) | Method for treating sleep disorder by regulating central nerves | |
CN114786640A (en) | Intelligent control device, control method thereof and intelligent wearable equipment | |
CN207503648U (en) | Neural feedback apparatus and system | |
CN104622468A (en) | Deep brain stimulation system with predication function | |
EP2166935B1 (en) | Methods and systems for controlling body parts and devices using ipsilateral motor cortex and motor related cortex | |
CN205988477U (en) | Physical and psychological rehabilitation feedback training device | |
CN110101366A (en) | A kind of sleep monitor system | |
CN113332560A (en) | Pillow with elastic pillow body | |
Zhang et al. | Recent progress in wearable brain–computer interface (BCI) devices based on electroencephalogram (EEG) for medical applications: a review | |
KR102538311B1 (en) | Integrated Transcranial Direct Current Stimulation (tDCS) and Near Infrared Spectroscopy (fNIRS) Based Wearable Portable Brain Function Activation Promotion and Monitoring System |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |