CN106309751A - Preparation method for traditional Chinese medicine composition for treating conglobata acne - Google Patents
Preparation method for traditional Chinese medicine composition for treating conglobata acne Download PDFInfo
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- CN106309751A CN106309751A CN201610995422.6A CN201610995422A CN106309751A CN 106309751 A CN106309751 A CN 106309751A CN 201610995422 A CN201610995422 A CN 201610995422A CN 106309751 A CN106309751 A CN 106309751A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/84—Valerianaceae (Valerian family), e.g. valerian
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention discloses a preparation method for a traditional Chinese medicine composition for treating conglobata acne. The method comprises the following steps: 1) weighting platycodon grandiflorum, patrinia, honeysuckle flowers, elephantopus scaber, borneol, saxifraga stolonifera, ephedra, tetrapanax papyriferus and plantain herb by weight part; 2) cleaning the traditional Chinese medicine raw materials, and then putting into clean water or pure water and soaking for 1 hour; 3) transferring the traditional Chinese medicine raw materials and the soaking solution into a decocting pot, covering and decocting; 4) while decocting, utilizing strong fire to boil the solution in the decocting pot and then decocting with slow fire; 5) adding water for secondarily decocting, boiling with strong fire and decocting with slow fire; 6) filtering the solution in the decocting pot, thereby acquiring the filtrate, namely, the orally taken medicine. According to the preparation method provided by the invention, the effective constituents in the traditional Chinese medicine raw materials can be effectively extracted and can more effectively exert the effect, the preparation method is suitable for industrial production and the medicinal property of the raw materials is not damaged as far as possible.
Description
Technical field
The present invention relates to tcm field, specifically refer to the preparation of a kind of Chinese medicine composition for treating Acne conglobata
Method.
Background technology
Acne is that a kind of chronic inflammatory skin of pilosebaceous unit is sick, and the generation of acne is main and sebum secretion mistake
The factors such as many, pilosebaceous duct blocking, antibacterial infection and inflammatory reaction are closely related.Adolesce and male in descendant's body swash
The level of element particularly testosterone raises rapidly, promotes that sebaceous gland is grown and produces a large amount of sebum.Pilosebaceous duct simultaneously
Dyskeratosis causes catheter blockage, dyssebacia, forms horn plug i.e. micropowder thorn.Multiple-microorganism especially Cuo in hair follicle
Skin ulcer propionibacterium amount reproduction, the lipase that propionibacterium acnes produces decomposes sebum and generates free fatty, simultaneously chemotactic inflammation
Cell and medium, finally induce and increase the weight of inflammatory reaction.And Acne conglobata is one the most serious in acne type, it is one
Kind of multifactor property disease, main generation with sebum increase, and follicular orifice epithelium keratinization is hyperfunction and in hair follicle, propanoic acid Propiobacterium breeds
Relevant, also there is certain inherited genetic factors simultaneously.Acne conglobata is more common in youth, is apt to occur in the sebaceous gland such as buccal, forehead, thoracic dorsal
Relatively enrich position.
Acne is often sent out in juvenile era, and its cause of disease includes again many factors, although is the common disease of adolescence, but has
Easily there is the most serious clinical manifestation in a little people, may leave permanent cicatrix without treatment timely, for
Later democratic meeting affects.And there are currently no a kind of medicine the most effectively solving acne problems, greatly
Many is all the medicament smeared based on antibiotic medicine and external, is merely able to alleviate symptom for the moment, and taking stopgap measures of namely often saying is not controlled
This.
Summary of the invention
It is an object of the invention to provide a kind of Chinese drug-treated group that can the most effectively solve Acne conglobata
The preparation method of compound.
The present invention is achieved through the following technical solutions: the preparation side of a kind of Chinese medicine composition for treating Acne conglobata
Method, comprises the following steps:
(1) represent with weight portion, weigh Radix Platycodonis 4 ~ 8 parts, Herba Patriniae 5 ~ 10 parts, Flos Lonicerae 3 ~ 7 parts, Herba Elephantopi scaberis 3 ~ 8 parts, Borneolum Syntheticum 4 ~ 9
Part, Herba Saxifragae 2 ~ 6 parts, 4 ~ 11 parts of Herba Ephedrae, Medulla Tetrapanacis 2 ~ 7 parts, Herba Plantaginis 3 ~ 9 parts；
(2) Chinese herb after first weighing cleans up, and is put into by Chinese herb in clear water or pure water and soak after cleaning
Steeping one hour, soaking institute's water requirement is 1.7 ~ 2.3L；
(3) Chinese herb and soak thereof after then soaking are transferred in medicine decocting tank together, add a cover and decoct；
(4) when decocting, before not boiling the most with high heat, after the solution in medicine decocting tank seethes with excitement, lid is taken off, and use slow fire instead again
Decoct 30 ~ 60 minutes, need to stir 5 ~ 6 times during whole boiling medicine；
(5) second time decocts Chinese herb 2 ~ 5cm that need to add water no, then or first boils with high heat, then decocts with slow fire
Boil 15 ~ 23 minutes；
(6) being filtered by the solution in Decocting pot, filtrate is endo-medicine.
For optimizing the effect of drugs of medicine, further determining that, the soaking container employed in described step (2) is uncovered glass
Glass tank.
For optimizing the effect of drugs of medicine, further determining that, the medicine decocting tank in described step (3) is marmite or ceramic sand
Pot.
For optimizing the effect of drugs of medicine, further determining that, Chinese herb and soak thereof are turned in (3) by described step
Move past journey method particularly includes: Chinese herb and soak thereof after soaking are poured in the medicine decocting tank being inserted with funnel, and
With clear water or pure water cleaning and dipping container, and cleanout fluid is poured in medicine decocting tank along funnel.
For optimizing the effect of drugs of medicine, further determine that, in described step (3) before adding a cover decoction also with clear water or
Pure water did not had Chinese herb 3 ~ 6cm.
The crude drug pharmacology of a kind of Chinese medicine composition for treating Acne conglobata of the present invention:
Radix Platycodonis: bitter in the mouth, pungent, property is put down.Return lung meridian.Lung qi dispersing eliminates the phlegm, sore-throat relieving evacuation of pus.Belong to Qinghua heat of classification under expectorants, antitussives and anti-asthmatics medicine
Expectorant medicine.
Herba Patriniae: cool in nature, acrid in the mouth, hardship.Return stomach warp, large intestine channel, Liver Channel.Heat-clearing and toxic substances removing, removing blood stasis and expelling pus.Belong to antipyretic subordinate
The heat and toxic materials clearing away medicine of classification.
Flos Lonicerae: cold in nature, sweet in the mouth.Return lung meridian, heart channel, stomach warp.Heat-clearing and toxic substances removing, wind-heat dissipating.Belong to antipyretic subordinate classification
Heat and toxic materials clearing away medicine.
Herba Elephantopi scaberis: cold in nature, bitter in the mouth, micro-pungent.Return lung meridian, Liver Channel, kidney channel.Heat-clearing and toxic substances removing, inducing diuresis to remove edema.Belong to lower point of antipyretic
The heat and toxic materials clearing away medicine of class.
Borneolum Syntheticum: cold, acrid in the mouth, hardship.GUIXIN warp, spleen channel, lung meridian.Have one's ideas straightened out refreshment, clearing away heat to alleviate pain.Belong to awaking drug.
Herba Saxifragae: cold in nature, mildly bitter flavor.Return lung meridian, stomach warp.Dispel the wind, heat clearing away, blood-cleaning detoxifying.Belong to antipyretic subordinate classification
Heat removing and blood cooling medicine.
Herba Ephedrae: warm in nature, acrid in the mouth, micro-hardship.Return lung meridian, bladder warp.Diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.Belong to diaphoretic medicine
The pungent and warm medicine for relieving the exterior syndrome of subordinate's classification.
Medulla Tetrapanacis: cold nature, sweet in the mouth, light.Return lung meridian, stomach warp.Clearing away heat and promoting diuresis, ventilation stimulating milk secretion.Belong to damp-clearing drug subordinate to divide
The stranguria-relieving diuretic of class.
Herba Plantaginis: cold in nature, sweet in the mouth.Return Liver Channel, kidney channel, lung meridian, small intestine meridian.Clearing away heat and promoting diuresis, eliminates the phlegm, removing heat from blood, removing toxic substances.Belong to profit
The stranguria-relieving diuretic of water eliminating dampness by diuresis medicine subordinate classification.
The present invention compared with prior art, has the following advantages and beneficial effect:
The present invention is by studying the pathogeny of Acne conglobata, thus is with prescription targetedly according to result of study, adopts
By directly oral mode, it is possible to play the effects such as heat-clearing and toxic substances removing, blood circulation promoting and dispersing pathogen accumulation, inducing diuresis to remove edema, evident in efficacy, and by certain
Time take the problem that acne takes place frequently that can fundamentally solve, and basic thing untoward reaction.
Detailed description of the invention
Embodiments of the invention are described below in detail.
Embodiment 1:
A kind of Chinese medicine composition for treating Acne conglobata of the present embodiment, represents with weight portion, including Radix Platycodonis 4 ~ 8 parts,
Herba Patriniae 5 ~ 10 parts, Flos Lonicerae 3 ~ 7 parts, Herba Elephantopi scaberis 3 ~ 8 parts, Borneolum Syntheticum 4 ~ 9 parts, Herba Saxifragae 2 ~ 6 parts, 4 ~ 11 parts of Herba Ephedrae, Medulla Tetrapanacis 2 ~ 7
Part, Herba Plantaginis 3 ~ 9 parts.
The preparation method of medicine of the present invention, comprises the following steps:
(1) represent with weight portion, weigh Radix Platycodonis 4 ~ 8 parts, Herba Patriniae 5 ~ 10 parts, Flos Lonicerae 3 ~ 7 parts, Herba Elephantopi scaberis 3 ~ 8 parts, Borneolum Syntheticum 4 ~ 9
Part, Herba Saxifragae 2 ~ 6 parts, 4 ~ 11 parts of Herba Ephedrae, Medulla Tetrapanacis 2 ~ 7 parts, Herba Plantaginis 3 ~ 9 parts；
(2) Chinese herb after first weighing cleans up, and is put into by Chinese herb in clear water or pure water and soak after cleaning
Steeping one hour, soaking institute's water requirement is 1.7 ~ 2.3L；
(3) Chinese herb and soak thereof after then soaking are transferred in medicine decocting tank together, add a cover and decoct；
(4) when decocting, before not boiling the most with high heat, after the solution in medicine decocting tank seethes with excitement, lid is taken off, and use slow fire instead again
Decoct 30 ~ 60 minutes, need to stir 5 ~ 6 times during whole boiling medicine；
(5) second time decocts Chinese herb 2 ~ 5cm that need to add water no, then or first boils with high heat, then decocts with slow fire
Boil 15 ~ 23 minutes；
(6) being filtered by the solution in Decocting pot, filtrate is endo-medicine.
Embodiment 2:
A kind of Chinese medicine composition for treating Acne conglobata of the present embodiment, represents with weight portion, described Radix Platycodonis 5 parts, Herba Patriniae
Grass 7 parts, Flos Lonicerae 5 parts, Herba Elephantopi scaberis 6 parts, Borneolum Syntheticum 4 parts, Herba Saxifragae 5 parts, 6 parts of Herba Ephedrae, Medulla Tetrapanacis 2 parts, Herba Plantaginis 5 parts..
Embodiment 3:
A kind of Chinese medicine composition for treating Acne conglobata of the present embodiment, represents with weight portion, described Radix Platycodonis 4 parts, Herba Patriniae
Grass 5 parts, Flos Lonicerae 4 parts, Herba Elephantopi scaberis 4 parts, Borneolum Syntheticum 6 parts, Herba Saxifragae 4 parts, 4 parts of Herba Ephedrae, Medulla Tetrapanacis 3 parts, Herba Plantaginis 3 parts..
Embodiment 4:
A kind of Chinese medicine composition for treating Acne conglobata of the present embodiment, represents with weight portion, described Radix Platycodonis 7 parts, Herba Patriniae
Grass 8 parts, Flos Lonicerae 5 parts, Herba Elephantopi scaberis 6 parts, Borneolum Syntheticum 5 parts, Herba Saxifragae 6 parts, 9 parts of Herba Ephedrae, Medulla Tetrapanacis 4 parts, Herba Plantaginis 8 parts.
Utilize medicine of the present invention for the clinical statistics data of various Acne conglobata patients:
Through the Clinical practice of 400 example patients, wherein man patient 274, female patient 126 example, medication age object 14 ~ 40 years old.Its
Middle minimum 16 years old, maximum 40 years old, 25 years old mean age；Slight Acne conglobata case 212 example, moderate Acne conglobata case
151 examples, severe Acne conglobata case 37 example.
Model case:
1, thank certain, female, 24 years old, school postgraduate, facial acne symptom originate with 2 years before, because of prepare for the postgraduate qualifying examination study often stay up late, lead
Causing self work and rest irregular, and stress is big, facial oil secretion increases the weight of, and starts the symptom such as acne and pimple occur, so
Between latter 2 years, face has the acne of new life always, and starts to increase the weight of at nearest one month, and pustule occurs, and sends out with face
Scorching symptom.Using prescription in the group of the embodiment of the present invention 2, and take 4 courses for the treatment of on time, face does not has secondary acne and mound
Rash, then sleep quality is improved.
2, slowly certain, man, 31 years old, just long on the face when of being educated in the university had acne, adds that the many learning pressures of lessons are big, on the face
Acne is the most serious.The cleanest overgrow with bronzing goose pimples, it appears the most dazzling on the face, impact image.The most partly
In year, Mr. Xu is once in some hospitalizes, but effect is unstable, bad during fashion, and it is the most multiple to stop liniment
Send out.Prescription after on time taking in the group of embodiment 1 in patient uses the present invention, whole face state is obviously improved, acne
Newly sending out, complexion is ruddy.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that: not
Depart from and these embodiments can be carried out multiple change under the principle of the present invention and objective, revise, replace and modification, the present invention's
Scope is limited by claim and equivalent thereof.
Claims (5)
1. the preparation method being used for treating the Chinese medicine composition of Acne conglobata, it is characterised in that: comprise the following steps:
(1) represent with weight portion, weigh Radix Platycodonis 4 ~ 8 parts, Herba Patriniae 5 ~ 10 parts, Flos Lonicerae 3 ~ 7 parts, Herba Elephantopi scaberis 3 ~ 8 parts, Borneolum Syntheticum 4 ~ 9
Part, Herba Saxifragae 2 ~ 6 parts, 4 ~ 11 parts of Herba Ephedrae, Medulla Tetrapanacis 2 ~ 7 parts, Herba Plantaginis 3 ~ 9 parts；
(2) Chinese herb after first weighing cleans up, and is put into by Chinese herb in clear water or pure water and soak after cleaning
Steeping one hour, soaking institute's water requirement is 1.7 ~ 2.3L；
(3) Chinese herb and soak thereof after then soaking are transferred in medicine decocting tank together, add a cover and decoct；
(4) when decocting, before not boiling the most with high heat, after the solution in medicine decocting tank seethes with excitement, lid is taken off, and use slow fire instead again
Decoct 30 ~ 60 minutes, need to stir 5 ~ 6 times during whole boiling medicine；
(5) second time decocts Chinese herb 2 ~ 5cm that need to add water no, then or first boils with high heat, then decocts with slow fire
Boil 15 ~ 23 minutes；
(6) being filtered by the solution in Decocting pot, filtrate is endo-medicine.
The preparation method of a kind of Chinese medicine composition for treating Acne conglobata the most according to claim 1, it is characterised in that:
Soaking container employed in described step (2) is open glass tank.
3., according to the preparation method of a kind of Chinese medicine composition for treating Acne conglobata of claim 1 or 2, its feature exists
In: the medicine decocting tank in described step (3) is marmite or pottery marmite.
4., according to the preparation method of a kind of Chinese medicine composition for treating Acne conglobata of claim 1 or 2, its feature exists
In: by Chinese herb and soak transfer process thereof in described step (3) method particularly includes: the Chinese medicine after soaking is former
Material and soak thereof are poured in the medicine decocting tank being inserted with funnel, and with clear water or pure water cleaning and dipping container, and by cleanout fluid
Pour in medicine decocting tank along funnel.
5., according to the preparation method of a kind of Chinese medicine composition for treating Acne conglobata of claim 1 or 2, its feature exists
In: described step (3) there also was not Chinese herb 3 ~ 6cm with clear water or pure water before adding a cover decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610995422.6A CN106309751A (en) | 2016-11-11 | 2016-11-11 | Preparation method for traditional Chinese medicine composition for treating conglobata acne |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610995422.6A CN106309751A (en) | 2016-11-11 | 2016-11-11 | Preparation method for traditional Chinese medicine composition for treating conglobata acne |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631413A (en) * | 2012-04-28 | 2012-08-15 | 董博 | Chinese medicinal composition for treating acne |
| CN103239678A (en) * | 2013-05-15 | 2013-08-14 | 胡殿宾 | External traditional Chinese medicine liniment for treating acnes |
-
2016
- 2016-11-11 CN CN201610995422.6A patent/CN106309751A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631413A (en) * | 2012-04-28 | 2012-08-15 | 董博 | Chinese medicinal composition for treating acne |
| CN103239678A (en) * | 2013-05-15 | 2013-08-14 | 胡殿宾 | External traditional Chinese medicine liniment for treating acnes |
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Application publication date: 20170111 |
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