CN106309696A - Traditional Chinese medicine composition for treating hepatitis and liver cirrhosis - Google Patents
Traditional Chinese medicine composition for treating hepatitis and liver cirrhosis Download PDFInfo
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- CN106309696A CN106309696A CN201610778803.9A CN201610778803A CN106309696A CN 106309696 A CN106309696 A CN 106309696A CN 201610778803 A CN201610778803 A CN 201610778803A CN 106309696 A CN106309696 A CN 106309696A
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- chinese medicine
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- hepatitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Abstract
The invention provides traditional Chinese medicine composition for treating hepatitis and liver cirrhosis. The composition is prepared from raw materials as follows: dried human placenta, medicated leaven, Chinese angelica, citrus medica, perilla stems, christina loosestrife herbs, fresh rehmannia roots and red peony roots in a certain ratio. The traditional Chinese medicine composition can treat different kinds of hepatitis and liver cirrhosis, has a quite high curative effect and takes effect quickly; the hepatitis and the liver cirrhosis are not prone to relapse.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition treating hepatitis and liver cirrhosis.
Background technology
Hepatitis is the general designation of inflammation.Typically refer to by multiple paathogenic factor--such as virus, antibacterial, parasite, chemistry
Poisonous substance, medicine, ethanol, role of autoimmune factors etc. make liver cell be destroyed, and the function of liver suffers damage, and causes health one
Series malaise symptoms, and the exception of liver function index.Owing to the cause of disease causing hepatitis is different, although there is similar clinical table
Existing, but nosetiology, serology, damage mechanisms, clinical through and prognosis, liver outside damage, diagnose and the aspect such as treatment often
There is obvious difference.It should be noted that hepatitis described in generally our life, majority refers to by A type, B-mode, the third type
The viral hepatitis caused etc. hepatitis virus.Viral, bacillary (such as ameba) Drug, ethanol can be divided into according to the cause of disease
Property, toxic, autoimmunity, nonalcoholic fatty liver etc..Acute hepatitis, chronic hepatitis can be divided into according to course of disease length
Deng.According to or without there is jaundice, acute hepatitis can be divided into acute icterohepatitis and acute anicteric hepatitis.Light according to the state of an illness
Weight degree, chronic hepatitis can be divided into slightly, moderate, severe etc..
The pathological changes of various hepatitis mainly at liver, has the clinical manifestation that some are similar, but at nosetiology, serum
, damage mechanisms, clinical through and prognosis, liver outside the aspect such as infringement often have obvious difference.
The early symptom of hepatitis and performance, such as: loss of appetite, digestive function is poor, enters abdominal distention after meal, does not has hunger sensation；Detest
Eat greasy food, if feed will cause Nausea and vomiting, susceptible tired after activity.
" hepatitis → hepatic fibrosis → liver cirrhosis → hepatocarcinoma " is the approach that hepatic disease develops, the existence shape to sufferer
Become sizable threat.Liver cirrhosis is clinical common chronic progressive external hepatopathy, one or more causes of disease make for a long time or repeatedly
With the diffusivity hepatic injury formed.Being posthepatitic cirrhosis at China's great majority, small part is alcoholic cirrhosis and schistosomicide
Property liver cirrhosis.Hepatic necrosis, remaining liver cell nodules regeneration, connective tissue proliferation widely is had with fine in histopathology
Dimension, every formation, causes lobules of liver structural deterioration and pseudolobuli to be formed, and liver gradually deforms, hardening and develop into liver cirrhosis.
In early days due to liver compensation more by force can non-evident sympton, stage is based on liver function injury and portal hypertension
Showing, and have multisystem to get involved, often there is upper gastrointestinal hemorrhage, hepatic encephalopathy, secondary infection, hypersplenism, abdomen in late period
The complication such as water, canceration.The cause of disease causing liver cirrhosis is a lot, can be divided into viral hepatitis liver cirrhosis, alcoholic cirrhosis, metabolism
Property liver cirrhosis, Cholestatic cirrhosis, hepatic vein backflow obstruction liver cirrhosis, autoimmune cirrhosis, poisonous substance and medicine
Property liver cirrhosis, nutritional cirrhosis, cryptogenic cirrhosis etc..
Clinical manifestation: can there be hepatitis clinical manifestation the compensatory phase, also can hide onset.Can have the most weak, abdominal distention, liver spleen are light
Degree enlargement, slight jaundice, liver palm, spider angioma.
Decompensated stage, has liver damage and portal hypertension disease group, mainly shows themselves in that
1) General Symptoms: weak, become thin, dim complexion, oliguria, lower limbs edema.
2) symptom of digestive tract: loss of appetite, abdominal distention, gastrointestinal dysfunction even malabsorption syndrome, liver source property glycosuria
Disease, may occur in which the symptom such as polyuria, polyphagia.
3) bleeding tendency and anemia；Gingiva bleeding gingival hemorrhage, epistaxis, purpura, anemia.
4) dyshormonia: spider angioma, liver palm, cutaneous pigmentation, female menstrual disorder, gynaecomastia, the parotid gland
Enlargement.
5) hypoproteinemia: double lower limbs edema, oliguria, seroperitoneum, liver source property hydrothorax.
6) portal hypertension: seroperitoneum, hydrothorax, splenomegaly, hypersplenism, portal vein Doppler flow mapping are set up, esophageal-gastric
End varicosis, abdominal wall varicosis.
It is currently used for treating hepatitis and the conventional medicine of liver cirrhosis, has that drug effect is inconspicuous, drug effect is slow, there is certain recurrence
The defects such as rate, so that a lot of patient constantly increasing the weight of because of hepatic fibrosis, finally cause digestive tract hemorrhage, hepatic encephalopathy, canceration
Dead etc. complication, bring great misery to patient and family members.
Summary of the invention
The present invention is to solve the treatment problem of hepatitis and liver cirrhosis, it is provided that a kind of new Chinese medicine composition.
Therefore, in one embodiment of the invention, it is provided that a kind of Chinese medicine composition treating hepatitis and liver cirrhosis, bag
Include the Chinese medicines such as Placenta Hominis.
In further embodiment of the present invention, described treatment hepatitis and the Chinese medicine composition of liver cirrhosis, comprise and have
A certain proportion of Placenta Hominis, Massa Medicata Fermentata, Radix Angelicae Sinensis, Fructus Citri, Caulis Perillae, Herba Lysimachiae, the Radix Rehmanniae and Radix Paeoniae Rubra.
In a preferred embodiment of the present invention, it is provided that a kind of Chinese medicine composition treating hepatitis and liver cirrhosis, by as follows
The raw material of weight portion is made: Placenta Hominis 5-15 part, Massa Medicata Fermentata 5-15 part, Radix Angelicae Sinensis 5-15 part, Fructus Citri 5-15 part, Caulis Perillae 5-10 part, gold
Money grass 5-10 part, Radix Rehmanniae 5-10 part, Radix Paeoniae Rubra 2-6 part.
In one highly preferred embodiment of the present invention, the optimum ratio of described Chinese medicine composition is: Placenta Hominis 10
Part, Massa Medicata Fermentata 10 parts, Radix Angelicae Sinensis 10 parts, Fructus Citri 10 parts, Caulis Perillae 5 parts, Herba Lysimachiae 10 parts, 5 parts of the Radix Rehmanniae, Radix Paeoniae Rubra 5 parts.
The preparation method of described Chinese medicine composition is: take each raw material, mixing, pulverizes, and crosses 100 mesh sieves, and conventional method is made
Tablet, pill or capsule.
Also can be produced by decocting method.In one embodiment, described decocting method includes: put into by the raw material of Chinese medicine of prescription
In container, add cold water and cover medicine plane, soak 15～20 minutes, added water no about 5 centimetres of medicine plane, and decocted 20-40 minute,
Obtain.
The Chinese medicine composition of the present invention can be soothing the liver, and yang invigorating is warming spleen and stopping diarrha, promoting the circulation of QI to relieve pain, suppressing the hyperactive liver pain relieving, invigorating the spleen and replenishing QI,
Dampness diuretic, and energy clearing away damp-heat, eliminating fire and detoxication, clearing away heat-damp and promoting diuresis, cool the blood dissipate blood stasis.All medicines are played altogether, jointly reach to cure hepatitis regulating liver-QI
The effect of hardening.Compared with existing Chinese medicine, there is quick result, cure rate is high, the advantage that is difficult to recurrence.
The situation that described Chinese medicine is used for clinic by inventor is as follows: 2014 to 2016 years, treats hepatitis 600 example, wherein
Man's 336 examples, female 264 example.State of an illness packet is shown in Table 1.Patient is administered orally and medicine described in external embodiment 1 every day, bfore meals, every day
Twice, every day one pair, taken with boiled water.It was 1 course for the treatment of with 1 month, after the course for the treatment of, observes curative effect.
Table 1: the state of an illness is grouped
| The state of an illness | Icterohepatitis | Hepatitis B | Hepatitis A | Liver cirrhosis | Hepatic ascites | Hepatitis C |
| Number of cases | 200 examples | 175 examples | 110 examples | 50 examples | 25 examples | 40 examples |
Therapeutic Method: the Chinese medicine composition of Example 1, every day 1 pair, conventional decocting, taken with boiled water, bfore meals, every day two
Secondary, it was 1 course for the treatment of with 1 month, after 1 course for the treatment of, observes curative effect.
Therapeutic outcome is shown in Table 2, and total effective rate reaches more than 96%, follows up a case by regular visits to 1 year, recurs 16 examples, and relapse rate is 2.7%.
Table 2: therapeutic outcome
Model case
1. Wang, female, suffers from hepatitis B 4 years, does not heals, within 2015, go to a doctor, after taking 1 course for the treatment of of medicine described in the embodiment of the present invention 1
Face yellowing disappears, and appetite improves, and detects only two indexs and be positive after continuing to take 1 course for the treatment of, examines after continuing to take 1 month
Surveying and only remaining 1 index is the positive, and hepatitis B disappears, continues to take 1 month and consolidate curative effect, follow up a case by regular visits to not recur so far.
2. Xing, female, within 2015, to go to a doctor, readme is tired, loss of appetite, after testing hepatomegaly, abnormal liver function, Huang occurs
Subcutaneous ulcer, shows as acute hepatitis, examines as hepatitis A, takes tired disappearance after 1 course for the treatment of of medicine described in the embodiment of the present invention 1, detection
Jaundice disappears, and appetite strengthens, and after continuing to take 1 course for the treatment of, described symptom all disappears, and continues to take half course for the treatment of and consolidates curative effect,
Follow up a case by regular visits to not recur so far.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, it will be recognized to those skilled in the art that this
The embodiment of invention is not limited to that.
Embodiment 1
Placenta Hominis 10g, Massa Medicata Fermentata 10g, Radix Angelicae Sinensis 10g, Fructus Citri 10g, Caulis Perillae 5g, Herba Lysimachiae 10g, Radix Rehmanniae 5g, Radix Paeoniae Rubra 5g.
Described in the present embodiment, medicine routine is prepared as pill, bfore meals, every day twice, every day one pair, taken with boiled water.With
Within 1 month, it is 1 course for the treatment of, after the course for the treatment of, observes curative effect.
Embodiment 2
Placenta Hominis 15g, Massa Medicata Fermentata 15g, Radix Angelicae Sinensis 15g, Fructus Citri 5g, Caulis Perillae 10g, Herba Lysimachiae 5g, Radix Rehmanniae 8g, Radix Paeoniae Rubra 4g.
Every day 1 pair, conventional decocting, taken with boiled water, bfore meals, every day twice, was 1 course for the treatment of with 1 month, 1 course for the treatment of
Rear observation curative effect.
Embodiment 3
Placenta Hominis 15g, Massa Medicata Fermentata 15g, Radix Angelicae Sinensis 10g, Fructus Citri 10g, Caulis Perillae 5g, Herba Lysimachiae 5g, Radix Rehmanniae 5g, Radix Paeoniae Rubra 5g.
Every day 1 pair, conventional decocting, taken with boiled water, bfore meals, every day twice, was 1 course for the treatment of with 1 month, 1 course for the treatment of
Rear observation curative effect.
Claims (7)
1. treat a Chinese medicine composition for hepatitis and liver cirrhosis, the Chinese medicine such as including Placenta Hominis.
2. the Chinese medicine composition of claim 1, comprises and has a certain proportion of Placenta Hominis, Massa Medicata Fermentata, Radix Angelicae Sinensis, Fructus Citri, Caulis Perillae, money
Grass, the Radix Rehmanniae and Radix Paeoniae Rubra.
3. the Chinese medicine composition of claim 1-2, is made up of the raw material of following weight portion: Placenta Hominis 5-15 part, Massa Medicata Fermentata 5-15 part,
Radix Angelicae Sinensis 5-15 part, Fructus Citri 5-15 part, Caulis Perillae 5-10 part, Herba Lysimachiae 5-10 part, Radix Rehmanniae 5-10 part, Radix Paeoniae Rubra 2-6 part.
4. the Chinese medicine composition of claim 1-3, its optimum ratio is: Placenta Hominis 10 parts, Massa Medicata Fermentata 10 parts, Radix Angelicae Sinensis 10 parts, Fructus Citri
10 parts, Caulis Perillae 5 parts, Herba Lysimachiae 10 parts, 5 parts of the Radix Rehmanniae, Radix Paeoniae Rubra 5 parts.
5. the method for preparation Chinese medicine composition described in claim 1-4, including taking each raw material, mixing, pulverize, cross 100 mesh sieves,
Conventional method makes tablet, pill or capsule.
6. the method for preparation Chinese medicine composition described in claim 1-4, it is decocting method.
7. the method for claim 6, described decocting method includes: put in container by the raw material of Chinese medicine of prescription, adds cold water and covers medicine
Plane, soaks 15～20 minutes, added water no about 5 centimetres of medicine plane, and decocted 20-40 minute, to obtain final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610778803.9A CN106309696A (en) | 2016-08-31 | 2016-08-31 | Traditional Chinese medicine composition for treating hepatitis and liver cirrhosis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610778803.9A CN106309696A (en) | 2016-08-31 | 2016-08-31 | Traditional Chinese medicine composition for treating hepatitis and liver cirrhosis |
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| CN201610778803.9A Pending CN106309696A (en) | 2016-08-31 | 2016-08-31 | Traditional Chinese medicine composition for treating hepatitis and liver cirrhosis |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1481876A (en) * | 2003-07-25 | 2004-03-17 | 吕运一 | Medication for virus hepatitis and hepatocirrhosis |
| CN1569189A (en) * | 2004-04-23 | 2005-01-26 | 丁佐辉 | Medicine for treating hepatitis A and B |
| CN1616045A (en) * | 2004-09-27 | 2005-05-18 | 简光富 | Chinese medicine composition for treating icterus hepatitis |
| CN101612360A (en) * | 2009-07-17 | 2009-12-30 | 肖嘉惠 | The medicine of treatment hepatitis, liver cirrhosis, hepatocarcinoma |
| CN102526625A (en) * | 2012-02-14 | 2012-07-04 | 张秀兰 | Medicament for treating hepatitis B and preparation method for medicament |
-
2016
- 2016-08-31 CN CN201610778803.9A patent/CN106309696A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1481876A (en) * | 2003-07-25 | 2004-03-17 | 吕运一 | Medication for virus hepatitis and hepatocirrhosis |
| CN1569189A (en) * | 2004-04-23 | 2005-01-26 | 丁佐辉 | Medicine for treating hepatitis A and B |
| CN1616045A (en) * | 2004-09-27 | 2005-05-18 | 简光富 | Chinese medicine composition for treating icterus hepatitis |
| CN101612360A (en) * | 2009-07-17 | 2009-12-30 | 肖嘉惠 | The medicine of treatment hepatitis, liver cirrhosis, hepatocarcinoma |
| CN102526625A (en) * | 2012-02-14 | 2012-07-04 | 张秀兰 | Medicament for treating hepatitis B and preparation method for medicament |
Non-Patent Citations (1)
| Title |
|---|
| 陈其福: "肝炎在临床中的辩证论治", 《中医中药》 * |
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Application publication date: 20170111 |
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