CN106306423A - Oral iron supplement for livestock and preparation method thereof - Google Patents
Oral iron supplement for livestock and preparation method thereof Download PDFInfo
- Publication number
- CN106306423A CN106306423A CN201610688023.5A CN201610688023A CN106306423A CN 106306423 A CN106306423 A CN 106306423A CN 201610688023 A CN201610688023 A CN 201610688023A CN 106306423 A CN106306423 A CN 106306423A
- Authority
- CN
- China
- Prior art keywords
- iron
- poultry
- iron supplementary
- supplementary
- oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
Abstract
The invention provides an oral iron supplement for livestock and a preparation method. The oral iron supplement for the livestock adopts a dosage form of an oil-based suspension, and is prepared by mixing a compound iron supplement, liquid oil, a wetting agent, a flavoring agent, an antioxidant and a viscosity modifier according to a certain proportion and then grinding by using a bead mill. The oral iron supplement for the livestock is high in iron content and good in fluidity, uses the oil as a solvent, is good in palatability, is especially suitable for supplementing iron and zinc to newborn animals, and can effectively prevent iron deficiency anemia of piglets, cattle and sheep; the oral iron supplement for the livestock can be quantitatively administrated by using a hand-operated pump, with easy and convenient operation, and compared with an intramuscular iron supplementation, administration by using the hand-operated pump has the advantages as follows: animal stress can be reduced, the carcass quality is not affected, other nutrients needed by young livestock can be supplemented at the same time, the labor intensity of artificial injection can be reduced and the productivity is improved.
Description
Technical field
The present invention relates to animal feed additive field, be specifically related to a breeding stock oral iron supplementary and preparation method thereof.
Background technology
Ferrum element is one of indispensable trace element of young stock growth promoter.Ferrum storage in newborn young stock body is less, with
Time the ferrum that obtained by milk the most extremely limited, and young stock fast-growth during suckling, need substantial amounts of ferrum, therefore open young stock
Before beginning material feeding, need to additionally supplement ferrum, otherwise can hinder the early development of young stock because of iron deficiency, make young stock poor growth.With piglet
As a example by, mainly have following 3 kinds at present the mode of piglet iron supplement: the indirect supplementary feeding of sow, Piglet by Oral iron supplement and intramuscular injection are mended
Ferrum.
In three of the above ferrous supplement method, by the indirect supplementary feeding of sow feed, increasing chalybeate extremely has to piglet iron supplement effect
Limit；Piglet by Oral iron supplement is generally difficult to control iron supplement dosage, and existing oral iron-supplementing preparation on market, is generally molten with water
Agent or dispersant, complex manufacturing, need aseptic packaging, palatability is poor, and piglet easily spues and affects dosage, simultaneously because containing
Iron is relatively low, is limited by the reason of the amount of gavaging, and it is not enough that single gavages iron supplement amount, it is therefore desirable to repeatedly forces to gavage, increases work
Intensity.Therefore both the above method seldom uses, and the commonly used ferrous supplement method of current plant is intramuscular injection iron supplement, muscle
Injection iron dextran definite effect, can effectively prevent piglet anaemia, but there is also that Animal stress is big, increase employee works by force
Degree, the problem affecting ketone body quality.
Summary of the invention
It is an object of the invention to provide the oral iron supplementary of a breeding stock, iron content is high, good fluidity, and palatability is good, efficiently
Iron supplement, produces, easy to use, it is possible to for replacing the most commonly used injection iron supplement injection, thus avoid because of intramuscular injection
The untoward reaction such as swelling that chalybeate causes, anorexia, allergy, reduce poultry with stress, alleviate the labor intensity of manual injection.
For realizing above-mentioned technical purpose, the technical scheme is that the oral iron supplementary of a breeding stock, with percentage by weight
Meter, described poultry the ratio of each component is with oral iron supplementary: compound iron supplementary 30%～60%, and wetting agent 0.5%～10% is viscous
Degree regulator 0.05%～0.5%, oil antioxidant 0.01～0.05%, correctives 0.03～0.1%, surplus is liquid oil
Fat.
Described compound iron supplementary is iron dextran, ferrous sulfate, ferrous lactate, ferrous fumarate, ferrous methionine, sweet ammonia
At least one in acid ferrum, ferrous porphyrin, adds that trace element and/or vitamin conjugate form.
Described wetting agent is phospholipid.
Described viscosity modifier is aerosil or nanometer Montmorillonitum powder, or aerosil covers de-with nanometer
The mixture of stone powder.
Described liquid fat is at least one in Semen Lini oil, soybean oil, medium chain triglyceride.
Described poultry is oil system suspensoid with oral iron supplementary.
Described poultry can be gavaged to animal by hand pressure pump head with oral iron supplementary.
The present invention also provides for the breeding stock preparation method with oral iron supplementary, first compound iron supplementary, wetting agent, oils and fats is resisted
Oxidant, correctives, liquid fat are mixed by ratio requirement, are ground to required particle diameter by ball mill, add viscosity adjustment
Agent, stirs.
Being ground to particle diameter by ball mill is D90 ＜ 25 μm.
Described compound iron supplementary is iron dextran, ferrous sulfate, ferrous lactate, ferrous fumarate, ferrous methionine, sweet ammonia
At least one in acid ferrum, ferrous porphyrin, adds that trace element and/or vitamin conjugate form.
Described wetting agent is phospholipid.
Described viscosity modifier is aerosil or nanometer Montmorillonitum powder, or aerosil covers de-with nanometer
The mixture of stone powder.
Described liquid fat is at least one in Semen Lini oil, soybean oil, medium chain triglyceride.The present invention with oils and fats is
Solvent and dispersant, the suspensoid made is oil system suspensoid, when solid content is up to 30%～60%, still has very well
Mobility, available pressing pump bottle packaging, taken by hand pressure pump head pumping outlet, both overcome existing oral iron supplementary iron content low,
The defect that palatability is poor, young stock easily spues, overcomes again intramuscular injection and causes that Animal stress is big, affect ketone body quality, increase
The problem of staff labor intensity.
The invention have the advantage that
(1) can use the mode that gavages to animal iron supplement, compared with injection iron supplement, animal stress not, do not have swelling,
The untoward reaction such as anorexia, allergy, and prevent to a certain extent blood born diseases because of shared injection needle between animal phase
Propagate mutually.
(2) dosage form of the present invention is oil system suspensoid, and compared with the water system iron supplement product of normal oral, palatability is more preferable；Change
Learning good stability, be not suitable for growth of microorganism, therefore production, technology of the package simply, store the phase long.
(3) active constituent content is high, and perfusion amount is few, and single perfusion can meet the demand of animal iron supplement, is not susceptible to sink
Forming sediment and caking phenomenon, product mobility is preferable simultaneously, available pressing pump bottle packaging, is gavaged to animal by hand pressure pump head, perfusion side
Just, accurately.
There are some researches show, newborn young stock intestinal mucosa easily absorbs ferrum, and in the most several hours, heavy dose of oral iron supplementary, right
For hemoglobin synthesis, iron unilization is identical with injection.Iron content of the present invention is high, and good fluidity, using oils and fats as molten
Agent, palatability is good, at suckling efficient iron supplement in period, is particularly suited for the iron supplement of infant animal, zinc supplement, can effectively prevent pig, cattle,
The generation of the young stock iron deficiency anemias such as sheep；The present invention quantitatively can carry with handlance, simple to operation, with intramuscular injection iron supplement
Compare and can reduce Animal stress, do not interfere with ketone body quality, other nutrient needed for young stock can be supplemented simultaneously, also can alleviate
The labor intensity of manual injection, improves plant's production performance.
Detailed description of the invention
Below in conjunction with specific embodiment mode, the present invention is expanded on further.Should be understood that these embodiments are merely to illustrate this
Invention rather than restriction the scope of the present invention.Additionally, after having read present disclosure, those skilled in the art can be right
The present invention makes various changes or modifications, and these equivalent form of values fall within limited range of the present invention equally.
Embodiment 1,
Calculating in percentage by weight, a breeding stock consists of with oral iron supplementary:
Ferrum glycinate 10%
Ferrous porphyrin 8%
Zinc glycinate 8%
Vitamin C 4%
Phosphatidase 0 .5%
Aerosil 0.25%
Correctives (sucralose) 0.03%
Oil antioxidant (TBHQ) 0.01%
Decanoyl/octanoyl glycerides surplus.
Its preparation method is: the dispensing beyond aerosil is mixed by proportioning, is ground to particle diameter D90 with ball mill
＜ 25 μm, is subsequently adding aerosil, continues to be ground to aerosil fully dispersed.
Embodiment 2
Calculating in percentage by weight, one embodiment of the present of invention becomes to be grouped into:
Iron dextran 18%
Ferrum glycinate 14%
Ferrous porphyrin 12%
Zinc glycinate 12%
Vitamin C 4%
Phosphatidase 1 0%
Aerosil 0.05%
Correctives (sucralose) 0.03%
Oil antioxidant (TBHQ) 0.01%
Decanoyl/octanoyl glycerides surplus
Its preparation method is with embodiment 1.
Embodiment 3
Calculating in percentage by weight, one embodiment of the present of invention becomes to be grouped into:
Iron dextran 10%
Ferrum glycinate 15%
Ferrous porphyrin 8%
Zinc glycinate 9%
Calcium lactate 5%
Vitamin C 4%
Phospholipid 7%
Nanometer Montmorillonitum 0.5%
Correctives (sucralose) 0.03%
Oil antioxidant (TBHQ) 0.01%
Semen Lini oil, soybean oil surplus
Its preparation method is with embodiment 1.
Embodiment 4
Calculating in percentage by weight, an embodiment of the technical program becomes to be grouped into:
Iron dextran 10%
Ferrum glycinate 24%
Zinc glycinate 10%
Calcium lactate 5%
Vitamin C 4%
Vitamin A (500,000 IU/ gram) 0.2%
Vitamin E (98%) 0.5%
Vitamin D3 (500,000 IU/ gram) 0.1%
Phospholipid 7%
Aerosil 0.18%
Correctives (button is sweet) 0.001%
Oil antioxidant (TBHQ) 0.01%
Decanoyl/octanoyl glycerides surplus.
Its preparation method is with embodiment 1.
Embodiment 5, present invention application excess syndrome on newborn piglet.
Select childbirth on the same day, parity is close, kind is consistent, body condition is healthy, 10 sow litters of a same column home,
Rejecting weak son, adjusting every nest piglet head number is 12, is equally divided into 3 process when piglet 3 age in days after being weighed by every nest piglet,
4 piglets of each process, the left ear of piglet of process 1 is cut 1 ear and is lacked, gavages the oral iron supplement prepared by the 2mL embodiment of the present invention 4
Agent, the piglet auris dextra of process 2 is cut 1 ear and is lacked, inject 1mL iron dextran injection (Fe content 1g/10mL), processes the son of 3
Pig is not cut ear and lacks, and the most additionally supplements ferrum, as a control group.Weightening finish according to piglet and iron supplement blood-hemoglobin content after 10 days
Contrast iron supplement effect.
The effect of table 3 piglet difference ferrous supplement method
| Group | Process 1 (being administered orally) | Process 2 (injections) | Process 3 (comparisons) |
| Average initial weight (kg/ head) | 1.87±0.18 | 1.88±0.17 | 1.88±0.19 |
| Average 18 ages in days weight (kg/ head) | 5.73±0.51 | 5.65±0.73 | 5.30±0.66 |
| 13 age in days hemoglobin (g/100mL) | 8.10±0.76 | 8.32±0.83 | 7.10±0.62 |
Result shows, the poultry of the present invention can improve the weightening finish of suckling pig with oral iron supplementary and blood-hemoglobin contains
Amount, reaches to inject the effect that iron supplement is identical.And compared with injection iron supplement, gavage iron supplementary to piglet simple to operation, than note
Penetrate ferrum pin and can reduce Animal stress, and other nutrient needed for piglet can be supplemented simultaneously, improve pig farm production performance.
The present embodiment is as a example by piglet, but present invention is equally applicable to other domestic animals such as cattle, sheep etc., can obtain relatively equally
Good iron supplement effect.
Iron content of the present invention is high, and good fluidity, using oils and fats as solvent, palatability is good, at suckling efficient iron supplement in period；This
The available handlance of invention quantitatively carries, simple to operation, compares with intramuscular injection iron supplement and can reduce Animal stress, does not interferes with
Ketone body quality, can supplement other nutrient needed for young stock simultaneously, also can alleviate the labor intensity of manual injection, improves pig farm
Production performance.
It is more than the description to the embodiment of the present invention, by the described above to the disclosed embodiments, makes this area special
Industry technical staff is capable of or uses the present invention.Those skilled in the art are come by the multiple amendment to these embodiments
Saying and will be apparent from, generic principles defined herein can be in the situation without departing from the spirit or scope of the present invention
Under, realize in other embodiments.Therefore, the present invention is not intended to be limited to the embodiments shown herein, and is intended to symbol
Close the widest scope consistent with principles disclosed herein and features of novelty.
Claims (8)
1. a breeding stock is with iron supplementary is administered orally, it is characterised in that by weight percentage, and described poultry is with iron supplementary each component is administered orally
Proportioning is: compound iron supplementary 30%～60%, wetting agent 0.5%～10%, viscosity modifier 0.05%～0.5%, and oils and fats resists
Oxidant 0.01～0.05%, correctives 0.03～0.1%, surplus is liquid fat.
2. poultry as claimed in claim 1 is with oral iron supplementary, it is characterised in that described compound iron supplementary be iron dextran,
At least one in ferrous sulfate, ferrous lactate, ferrous fumarate, ferrous methionine, ferrum glycinate, ferrous porphyrin, adds trace unit
Element and/or vitamin conjugate form.
3. poultry as claimed in claim 1 is with iron supplementary is administered orally, it is characterised in that described wetting agent is phospholipid.
4. poultry as claimed in claim 1 is with iron supplementary is administered orally, it is characterised in that described viscosity modifier is aerosil
Or nanometer Montmorillonitum powder, or the mixture of aerosil and nanometer Montmorillonitum powder.
5. poultry as claimed in claim 1 is with iron supplementary is administered orally, it is characterised in that described liquid fat is Semen Lini oil, Semen sojae atricolor
At least one in oil, medium chain triglyceride.
6. the poultry as described in Claims 1 to 5 is arbitrary is with iron supplementary is administered orally, it is characterised in that described poultry with oral iron supplementary is
Oil system suspensoid.
A breeding stock the most as claimed in claim 1 is with iron supplementary is administered orally, it is characterised in that: described poultry can pass through with oral iron supplementary
Hand pressure pump head gavages to animal.
The a breeding stock the most as claimed in claim 1 preparation method of oral iron supplementary, it is characterised in that: first by compound iron supplement
Agent, wetting agent, oil antioxidant, correctives, liquid fat are mixed by ratio requirement, are ground to required grain by ball mill
Footpath, adds viscosity modifier, stirs.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610688023.5A CN106306423A (en) | 2016-08-19 | 2016-08-19 | Oral iron supplement for livestock and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610688023.5A CN106306423A (en) | 2016-08-19 | 2016-08-19 | Oral iron supplement for livestock and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106306423A true CN106306423A (en) | 2017-01-11 |
Family
ID=57744131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610688023.5A Pending CN106306423A (en) | 2016-08-19 | 2016-08-19 | Oral iron supplement for livestock and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106306423A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107223784A (en) * | 2017-06-30 | 2017-10-03 | 云南农业大学 | A kind of newborn piglet is adjusted and its application method with iron |
| CN108853053A (en) * | 2018-09-11 | 2018-11-23 | 安徽万士生物制药有限公司 | The production method of the quickly disintegrated dextran ironwork in one boar oral cavity |
| CN110353104A (en) * | 2019-07-29 | 2019-10-22 | 江门市得宝集团有限公司 | A kind of Animal nutrition hardening agent of replenishing and activating blood |
| CN112167444A (en) * | 2020-09-30 | 2021-01-05 | 陆文雄 | Feed additive for improving vitality immunity and promoting metabolism |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904507A (en) * | 2009-06-04 | 2010-12-08 | 上海久健生物科技发展有限公司 | Ferrous bisglycinate chelate nutritional composition and application thereof |
| CN101987113A (en) * | 2009-07-30 | 2011-03-23 | 天津瑞普生物技术股份有限公司 | Thickening and stable animal iron-supplement composition |
| CN103781497A (en) * | 2011-07-05 | 2014-05-07 | 莱茵霍尔德·维奇 | Iron supplement composition |
-
2016
- 2016-08-19 CN CN201610688023.5A patent/CN106306423A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101904507A (en) * | 2009-06-04 | 2010-12-08 | 上海久健生物科技发展有限公司 | Ferrous bisglycinate chelate nutritional composition and application thereof |
| CN101987113A (en) * | 2009-07-30 | 2011-03-23 | 天津瑞普生物技术股份有限公司 | Thickening and stable animal iron-supplement composition |
| CN103781497A (en) * | 2011-07-05 | 2014-05-07 | 莱茵霍尔德·维奇 | Iron supplement composition |
Non-Patent Citations (1)
| Title |
|---|
| 傅超美，等: "《中药药剂学》", 31 August 2014, 中国医药科技出版社 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107223784A (en) * | 2017-06-30 | 2017-10-03 | 云南农业大学 | A kind of newborn piglet is adjusted and its application method with iron |
| CN108853053A (en) * | 2018-09-11 | 2018-11-23 | 安徽万士生物制药有限公司 | The production method of the quickly disintegrated dextran ironwork in one boar oral cavity |
| CN108853053B (en) * | 2018-09-11 | 2021-03-30 | 安徽万士生物制药有限公司 | Production method of iron dextran product capable of being rapidly disintegrated in pig oral cavity |
| CN110353104A (en) * | 2019-07-29 | 2019-10-22 | 江门市得宝集团有限公司 | A kind of Animal nutrition hardening agent of replenishing and activating blood |
| CN112167444A (en) * | 2020-09-30 | 2021-01-05 | 陆文雄 | Feed additive for improving vitality immunity and promoting metabolism |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105053569B (en) | A kind of feed fat powder feed addictive and preparation method thereof | |
| CN106306423A (en) | Oral iron supplement for livestock and preparation method thereof | |
| CN103005177B (en) | Breeding boar feed additive | |
| US5686490A (en) | Method for breeding infant livestock and feed composition | |
| CN104222524B (en) | A kind of feeding water-solubility function fatty powder | |
| CN105076723B (en) | A kind of microencapsulation fat powder feed additive and preparation method thereof | |
| RU2405376C2 (en) | Premix for lactating cows | |
| Naik et al. | Lactation response of cross bred dairy cows fed on indigenously prepared rumen protected fat-A field trial | |
| KR101325566B1 (en) | Feed increasing CLA content in the goat milk and method for producing the same | |
| CN106538866A (en) | A kind of milking sow fatty powder and preparation method thereof | |
| CN104839498B (en) | A kind of DHA adjusting control agents and its chicken feed | |
| CN104222667A (en) | Ruminant rumen bypass stable -equilibrium fat powder and preparation method thereof | |
| CN103734518B (en) | Efficiently sheared, homogenized and emulsified oil powder | |
| Nawaz et al. | Effect of supplemental fat on dry matter intake, nutrient digestibility, milk yield and milk composition of ruminants. | |
| WO2012111277A1 (en) | Method for improving number of sows beginning to nurse or number of weaning sows | |
| CN104869842A (en) | Novel use of canthaxanthin and 25-hydroxy vitamin D3 | |
| CN104922064B (en) | A kind of nanoscale nutrient microemulsion and preparation method thereof for preventing and treating ketosis of dairy cows | |
| Nalęcz-Tarwacka et al. | The influence of carrot addition to cow's ration on the level of vitamins and fatty acids in cow milk. | |
| CN103844031A (en) | Nutritional feed additive capable of improving litter size of replacement gilt | |
| US9248155B2 (en) | Supplement composition and method of use | |
| CN108244361A (en) | A kind of replacement gilt mixed feed and preparation method thereof | |
| CN109892491A (en) | A kind of sow feed additive and preparation method thereof | |
| DE102006040425A1 (en) | Supplement, useful as additive to feed animals e.g. ruminants and beef cattle, comprises a homogeneous pulverulent composition of fat and starch | |
| Memiši et al. | The influence of presence of zinc in diet on production traits of goats. | |
| RU2523882C2 (en) | Vitamin-mineral premix "success" for highly productive cows |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170111 |