CN106290945B - Sample adapter, sample positioning device and batch sample analysis method - Google Patents
Sample adapter, sample positioning device and batch sample analysis method Download PDFInfo
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- CN106290945B CN106290945B CN201510252132.8A CN201510252132A CN106290945B CN 106290945 B CN106290945 B CN 106290945B CN 201510252132 A CN201510252132 A CN 201510252132A CN 106290945 B CN106290945 B CN 106290945B
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- 238000012284 sample analysis method Methods 0.000 title abstract description 7
- 238000004458 analytical method Methods 0.000 claims description 7
- 230000006835 compression Effects 0.000 claims description 7
- 238000007906 compression Methods 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 4
- 238000005070 sampling Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 3
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 238000003908 quality control method Methods 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000003139 buffering effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010339 medical test Methods 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Abstract
The invention provides a sample adapter, which comprises a shell with an opening at one end, wherein the shell is provided with a hollow upper space, a sample cup pad is arranged in the lower space of the shell, a sample cup is accommodated in the upper space and is contacted with the sample cup pad, at least part of the outer wall of the sample cup is basically attached to the inner wall of the upper space, and a positioning structure is arranged on the outer wall of the shell. The invention also provides a sample positioning device with the carrier and the sample adapters, so that a plurality of sample adapters can be aligned and positioned, and a batch sample analysis method is provided.
Description
Technical Field
The present invention relates to the field of medical testing, and more particularly, to a sample adapter, a sample positioning device, and a batch sample analysis method using the same.
Background
Biological fluid samples, such as blood, saliva, urine, etc., are samples of a large number of tests per day in hospitals, social health centers, etc. These samples are sometimes collected in open sample cups or in flip-top sample cups, however, the sample cups must be open for testing and thus their positioning is important. These sample cups first require a vertical stable position to facilitate sample analysis by a sample analyzer, such as a blood analyzer sampling needle; secondly, if the sample cups are inspected by manually holding the sample cups, automation cannot be realized, and the efficiency is low.
Disclosure of Invention
In view of the foregoing, it is desirable to provide a sample adapter, sample positioning device, and batch sample analysis method.
A sample adapter comprises a shell with one end open, wherein the shell is provided with a hollow upper space, a sample cup pad is arranged in the lower space of the shell, a sample cup is accommodated in the upper space and is contacted with the sample cup pad, at least part of the outer wall of the sample cup is basically attached to the inner wall of the upper space, and a positioning structure is arranged on the outer wall of the shell.
Preferentially, the shell is provided with a notch downwards along the side wall from the end part where the opening is positioned, the sample cup is accommodated into the upper space from the opening, and the notch is partially exposed; the end of the sample cup pad facing the opening is provided with a groove for accommodating the bottom of the sample cup.
Preferably, the sample cup pad comprises a follow-up buffer seat and an elastic buffer device connected with the follow-up buffer seat, and the groove is arranged at the end part of the follow-up buffer seat facing the upper space.
Preferably, the housing is provided with a clamping groove, the sample cup comprises a cup body and a flip cover connected with the cup body, the cup body is accommodated in the upper space, and at least one part of the flip cover is suitable for being clamped in the clamping groove to open the cup body.
Preferentially, the lower edge of the notch is provided with a chute along the circumferential direction of the shell, the clamping groove is upwards arranged from the upper edge of the chute, the flip cover comprises a connecting arm connected with the cup body and a cover body positioned at the tail end of the connecting arm, and the sample cup pad enables the connecting arm to be clamped in the clamping groove.
Preferably, the side wall of the housing extends outwardly beyond the catch pin above the catch slot.
Preferably, the positioning structure is a pin protruding from an outer wall of the housing.
A sample positioning device for positioning a sample cup, comprising:
a sample adapter as described above; and
the sample adapter is loaded in the selected space bearing position, and the selected space bearing position is provided with a clamping structure matched with the positioning structure of the sample adapter.
Preferably, the detent structure is a vertical groove.
Preferably, a cutout is provided on one side of the carrier to partially open the plurality of spatial loading sites in an axial direction, the sample adapter is affixed with a barcode, and the barcode is aligned with the spatial loading site at the open position.
A batch sample analysis method, comprising:
providing a carrier having a plurality of spatial carrying locations;
receiving a plurality of sample adapters, wherein the sample adapters are provided with sample cups to be tested, the sample cups are filled with samples to be tested, and bar code information of the samples to be tested is attached to the sample adapters;
the carrier with the plurality of samples to be tested is moved to the sample analyzer so that the sample analyzer can perform continuous automatic sampling analysis on the plurality of samples to be tested.
In contrast to the prior art, the present invention provides a sample adapter having a sample cup pad in contact with a sample cup, at least a portion of the outer wall of which substantially conforms to the inner wall of the sample adapter, thereby stably positioning the sample cup. The sample positioning device is capable of loading sample adapters so that a plurality of sample adapters can be aligned and stably transported. Due to the adoption of the sample adapter and the sample positioning device, the sample analyzer can analyze batch samples, and is beneficial to realizing automation.
Drawings
Fig. 1 is a perspective view of a sample adapter provided in a first embodiment of the present invention.
Fig. 2 is another angular perspective view of the sample adapter of fig. 1.
Fig. 3 is a cross-sectional view of the sample adapter of fig. 1 housing a sample cup with a flip cap.
Fig. 4 is a perspective view of a sample adapter according to a second embodiment of the present invention with a sample cup having a flip cover.
Fig. 5 is a cross-sectional view of fig. 4.
Fig. 6 is a schematic perspective view of a carrier according to a third embodiment of the present invention.
Fig. 7 is a perspective view of the carrier of fig. 6 loaded with sample adapters.
Fig. 8 is a schematic view of a sample positioning device according to a fourth embodiment of the present invention.
Fig. 9 is a flowchart of a method for analyzing a batch sample according to a fifth embodiment of the present invention.
Description of the main reference signs
Sample adapter | 100,140 |
Sample cup | 10,14 |
Cup body | 11 |
Flip cover | 12 |
Connecting arm | 121 |
Cover body | 122 |
Shell body | 20,141 |
Sample cup pad | 30 |
An opening | 21,210 |
Notch | 22,220 |
Sliding chute | 23 |
Clamping groove | 24 |
Stop pin | 25 |
Follow-up buffer seat | 31 |
Elastic buffer device | 32 |
Groove | 35,351 |
Compression spring | 33 |
Pin pin | 26 |
Bar code | 27 |
Sample positioning device | 200,300 |
Bearing frame | 150 |
Space bearing position | 151,181 |
Incision | 152 |
Vertical groove | 153,183 |
Finger position | 155 |
The invention will be further described in the following detailed description in conjunction with the above-described figures.
Detailed Description
Referring to fig. 1 to 3, a sample adapter 100 according to a first embodiment of the present invention is provided for accommodating a sample cup 10. In this embodiment, the sample is a blood sample, the sample cup 10 includes a cup body 11 and a flip cover 12 connected to the cup body 11, and the flip cover 12 includes a connecting arm 121 and a cover 122 connected to the cup body 11. The sample adaptor 100 includes a housing 20 and a sample cup pad 30 disposed in the housing 20, wherein one end of the housing 20 is opened, an upper space is hollow for accommodating the sample cup 10, and the sample cup pad 30 is disposed in a lower space of the housing 20.
The casing 20 has a notch 22 formed downward from a part of the end of the opening 21, a chute 23 formed at the lower edge of the notch 22 along the circumferential direction of the casing 20, and a slot 24 formed at the upper edge of the chute 23. The side wall of the housing 20 extends outwardly above the catch 24 beyond the catch 25. The sample cup 10 can be placed into the housing 20 from the opening 21, the outer wall of the upper section of the sample cup 10 is substantially fitted to the inner wall of the upper space of the housing 20, and the lid 12 slides into the slide groove 23 from the lower edge of the notch 22 and the connecting arm 121 is finally caught in the catching groove 24, so that the lid 12 does not tilt at will, and the sample cup 10 can be kept open. The stopper pin 25 serves to further block the connection arm 121 and the cover 122.
It will be appreciated that in other embodiments, the slot 24 may be provided in other ways on the side wall of the housing 20, only a portion of the flip cover being required to be retained.
The sample cup pad 30 provides resiliency and cushioning to the sample cup 10 throughout the process of being placed into the housing 20 and retained in the catch slot 24, preventing damage to the sample cup 10. In this embodiment, the sample cup pad 30 includes a following buffer seat 31 and an elastic buffer device 32 connected to the following buffer seat 31, wherein the end of the following buffer seat 31 facing the opening 21 is used for contacting with the bottom of the cup 11 to provide an elastic buffer effect, and the end of the following buffer seat 31 may be provided with a groove 35 to partially accommodate the sharper bottom of the cup 11. The elastic buffer 32 is provided with a compression spring 33, one end of the compression spring 33 is fixed at the bottom of the housing 20, and the other end of the compression spring is abutted against the follow-up buffer seat 31 to provide follow-up property of the follow-up buffer seat 31 when being pressed by the sample cup 10.
The outer wall of the housing 20 is provided with a locating formation for cooperation with other components, in this embodiment a pin 26 protruding from the outer wall. The surface of the housing 20 opposite to the positioning structure has a bar code 27 for attaching a bar code of a sample cup, wherein the bar code records sample information of a sample contained in the sample cup, such as time of the sample, name of a patient, sample number, etc., and if the sample cup is filled with a quality control product or a calibrator, the bar code information also contains a target value of the quality control product or the calibrator.
Referring to fig. 4 and 5, a sample adapter 140 according to a second embodiment of the present invention is shown for accommodating a flip-less sample cup 14. The outer walls of the upper and middle sections of the sample cup 14 are substantially adhered to the inner wall of the upper space of the housing 141 of the sample adapter 140, and the bottom of the sample cup 14 can be received in the groove 351 of the sample cup pad 301. The end of the housing 141 is also provided with an opening 210 and a notch 220 to facilitate the taking out of the sample cup 14, the outer wall of the housing 141 also has a positioning structure, and the sample cup pad 301 also has a buffering function.
Referring to fig. 6 and 7, a sample positioning device 200 according to a third embodiment of the present invention includes the sample adapter 100 and the carrier 150. The carrier 150 has a plurality of space-bearing locations 151, and a cutout 152 is formed on one side of the carrier 150, so that the plurality of space-bearing locations 151 are partially opened in an axial direction. A finger position 155 is provided adjacent the cutout 152 to facilitate removal of the sample adapter 100. In this embodiment, the space-bearing locations 151 spaced apart by one are provided with a detent structure for cooperating with the positioning structure of the sample adapter 100, i.e. one space-bearing location 151 is left between every two sample adapters 100, so that the flip-cover 12 of one sample cup 10 and the stop pin 25 of the corresponding sample adapter 100 do not interfere with the other sample cup 10 and sample adapter 100. In this embodiment, the space-bearing position 151 has a vertical groove 153 that cooperates with the pin 26, and when the sample adapter 100 is loaded into the carrier 150, the pin 26 slides into the vertical groove 153, and the cooperation of the pin 26 and the vertical groove 153 prevents the sample adapter 100 from rotating in the space-bearing position 151. The barcode 27 of the sample adapter 100 is aligned with the open position of the space-bearing bit so as not to be obscured when reading the barcode 27. The carrier 150 may be laid flat on a conveyor belt so that the sample cups 10 are transported to a predetermined position.
It will be appreciated that the positioning structure of the housing 20 and the detent structure of the carrier 150 may be interchanged or otherwise cooperatively formed.
Referring to fig. 8, a sample positioning device 300 according to a fourth embodiment of the present invention is different from the sample positioning device 200 described above in that each space-carrying position 181 of the carrier 180 is provided with a vertical groove 183, i.e. is provided with a clamping structure, so that the sample adapters 140 can be continuously loaded in each space-carrying position 181, or can be loaded in each space-carrying position 181 at intervals, i.e. the arrangement of the sample adapters 140 is not limited.
Referring to fig. 9, a batch sample analysis method according to a fifth embodiment of the present invention is as follows:
providing a carrier 150 or 180 having a plurality of spatial carrying locations;
receiving a plurality of sample adapters 100 or 140, wherein the sample adapters 100 or 140 are provided with sample cups 10 or 14 to be tested, the sample cups 10 or 14 are provided with samples to be tested, and bar code information of the samples to be tested is attached to the sample adapters 100 or 140;
the carrier 150 or 180 containing a plurality of samples to be measured is transferred to a sample analyzer (not shown) so that the sample analyzer performs continuous automatic sampling analysis on the plurality of samples to be measured.
In summary, the sample adapter provided by the invention has the sample cup pad contacting the sample cup, and at least part of the outer wall of the sample cup is basically jointed with the inner wall of the sample adapter, so that the sample cup is stably positioned. In the sample adapter 100 with the clamping groove 24, the flip 12 of the sample cup 10 can be clamped, so that the flip 12 cannot tilt to prevent automatic detection of an instrument, the stop pin 25 provides a further stopping effect, the arrangement of a plurality of sample adapters 100 is provided with a direction basis, and the adapter bar codes 27 are accurately arranged outwards; the sample cup pad 30 provides an elastic buffer effect for the sample cup 10, protects the sample cup 10, and enables the sample cup 10 to have a certain elasticity when clamped. The sample positioning device 200 can load the sample adapters 100 so that a plurality of sample adapters 100 can be aligned and stably transferred. The front end of the sample adapter is provided with a position for pasting a sample bar code, so that a user can conveniently paste the bar code. The carrier 150 has a cutout to facilitate the bar code reading device to read the bar code on the adapter. With the sample adapter 100 and the sample positioning device 200 described above, a sample analyzer, such as a blood analyzer, can perform batch analysis of samples to be tested that are contained in a sample cup, allowing for automated analysis of samples that are not contained in a whole blood collection tube, but that are also batch-wise, as are samples in a collection tube.
The above examples are preferred embodiments of the present invention, but the embodiments of the present invention are not limited by the above examples, which are only for explaining the claims. The scope of the invention is not limited by the description. Any changes or substitutions that would be readily apparent to one skilled in the art within the scope of the present disclosure are intended to be included within the scope of the present invention.
Claims (10)
1. A sample adapter, characterized by: the device comprises a shell with an opening at one end, wherein the shell is provided with a hollow upper space, a sample cup pad is arranged in the lower space of the shell, a sample cup is accommodated in the upper space and is contacted with the sample cup pad, at least part of the outer wall of the sample cup is basically attached to the inner wall of the upper space, and a positioning structure is arranged on the outer wall of the shell;
the end of the sample cup pad, which faces the opening, is provided with a groove for accommodating the bottom of the sample cup; the sample cup pad comprises a follow-up buffer seat and an elastic buffer device connected with the follow-up buffer seat, wherein the groove is arranged at the end part of the follow-up buffer seat, which faces the upper space;
the end of the follow-up buffer seat facing the opening is used for contacting with the bottom of the sample cup to provide an elastic buffer effect; the elastic buffer device is provided with a compression spring, one end of the compression spring is fixed at the bottom of the shell, and the other end of the compression spring is abutted against the follow-up buffer seat so as to provide follow-up property of the follow-up buffer seat when the follow-up buffer seat is subjected to pressure of the sample cup.
2. The sample adapter of claim 1, wherein: the shell is provided with a notch downwards along the side wall from the end part where the opening is positioned, the sample cup is accommodated in the upper space from the opening, and the notch is partially exposed.
3. The sample adapter of claim 1, wherein: the shell is provided with a clamping groove, the sample cup comprises a cup body and a flip cover connected with the cup body, the cup body is accommodated in the upper space, and at least one part of the flip cover is suitable for being clamped in the clamping groove to enable the cup body to be opened.
4. A sample adapter as recited in claim 3, wherein: the shell is provided with a notch downwards along the side wall from the end part where the opening is located, the lower edge of the notch is provided with a chute along the circumferential direction of the shell, the chute is upwards arranged from the upper edge of the chute, the flip cover comprises a connecting arm connected with the cup body and a cover body positioned at the tail end of the connecting arm, and the sample cup pad enables the connecting arm to be clamped in the chute.
5. The sample adapter of claim 4, wherein: the side wall of the shell extends outwards beyond the stop pin above the clamping groove.
6. The sample adapter of claim 1, wherein: the positioning structure is a pin protruding out of the outer wall of the shell.
7. A sample positioning device for positioning a sample cup, comprising:
the sample adapter of any one of claims 1-6; and
the sample adapter is loaded in the selected space bearing position, and the selected space bearing position is provided with a clamping structure matched with the positioning structure of the sample adapter.
8. The sample positioning device of claim 7, wherein: the clamping structure is a vertical groove.
9. The sample positioning device of claim 7, wherein: one side of the bearing frame is provided with a notch, so that the plurality of space bearing positions are partially opened along the axial direction, the sample adapter is attached with a bar code, and the bar code is aligned to the opened position of the space bearing positions.
10. A method of batch sample analysis, comprising:
providing a carrier having a plurality of spatial carrying locations;
receiving a plurality of sample adapters, wherein the sample adapters are provided with sample cups to be tested, the sample cups are filled with samples to be tested, and bar code information of the samples to be tested is attached to the sample adapters; the sample adapter is the sample adapter of any one of claims 1 to 6;
the carrier with the plurality of samples to be tested is moved to the sample analyzer so that the sample analyzer can perform continuous automatic sampling analysis on the plurality of samples to be tested.
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CN201510252132.8A CN106290945B (en) | 2015-05-18 | 2015-05-18 | Sample adapter, sample positioning device and batch sample analysis method |
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CN201510252132.8A CN106290945B (en) | 2015-05-18 | 2015-05-18 | Sample adapter, sample positioning device and batch sample analysis method |
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CN106290945B true CN106290945B (en) | 2024-01-16 |
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