CN1062765C - Jaundice diminishing medicine good for liver - Google Patents
Jaundice diminishing medicine good for liver Download PDFInfo
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- CN1062765C CN1062765C CN98113763A CN98113763A CN1062765C CN 1062765 C CN1062765 C CN 1062765C CN 98113763 A CN98113763 A CN 98113763A CN 98113763 A CN98113763 A CN 98113763A CN 1062765 C CN1062765 C CN 1062765C
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Abstract
The present invention belongs to a medicine for treating viral hepatitis, more specifically, various dosage forms of traditional Chinese medicines are made by that Chinese herbal medicines, such as oriental wormwood or isatis root, etc., are used as main medicines and other Chinese herbal medicines are matched. The present invention comprises the ingredients of (by weight proportion) 15 to 70 portions of oriental wormwood, 10 to 40 portions of red sage root, 15 to 50 portions of honeysuckle flower, 2 to 10 portions of Chinese caterpillar fungus, 15 to 50 portions of lalang grass rhizome and 5 to 20 portions of curcuma root. The present invention has the functions of heat heating, toxin removal, diuresis induction, jaundice removal, spleen strengthening, liver calming, blood cooling, depression removal and essential qi benefiting. Compared with the existing similar medicines, the present invention has the advantages of no hurt of the stomach intestine at the time of liver treatment and liver protection, benefit to patients' absorption to the medicine and convenient restoration of the patients' physical strength.
Description
The invention belongs to a kind of medicine for the treatment of viral hepatitis, be principal agent specifically and be furnished with the Chinese medicine that other Chinese herbal medicine are made multiple dosage form with Chinese herbal medicine such as Herba Artemisiae Scopariae or Radix Isatidiss.
No matter acute viral hepatitis patient is, chronic very big to mankind's harm, and infection velocity is fast, and is ill wide, treats the untimely serious symptom that easily becomes, as liver cirrhosis, ascites, hepatic coma.The serious symptom mortality rate is 70-90%.At present the traditional Chinese medical science adopts clearing away heat-damp and promoting diuresis antidote (as Herba Artemisiae Scopariae soup) to viral hepatitis, and western medical treatment is washed one's hair etc. with hypertonic glucose, VC, liver Thailand and carried out liver protecting therapy, and chronic hepatitis is lacked specific drug.Using the interferon and the effective percentage of vidarabine use in conjunction treatment is 42.8%, and these medicines are undesirable and can not effect a radical cure the price height of medicine to hepatitis disease therapeutic effect.Herba Artemisiae Scopariae Decoction all on the books in " gold doctor outline " treatise on Febrile Diseases, its medicine composition has Herba Artemisiae Scopariae, Radix Et Rhizoma Rhei, gives birth to Fructus Gardeniae, and the function of detoxification of medicine is poor.Radix Et Rhizoma Rhei, living Fructus Gardeniae character bitter cold, Radix Et Rhizoma Rhei has the effect of capturing.Viral hepatitis patient itself with regard to body constitution a little less than, make patient's healthy energy more empty after the medication, resistance descends greatly, the improvement of unfavorable patient's state of an illness.Itself has gastrointestinal reaction viral hepatitis patient, and Radix Et Rhizoma Rhei, living Fructus Gardeniae weaken gastrointestinal function, and gastrointestinal is drained the absorption that is not easy to active drug soon, is unfavorable for the therapeutical effect of active drug.Virus should not be got rid of and amass in liver and easily stay heresy, and just the easy obstinate of the patient of morbidity forms chronic hepatitis.Existing Chinese medicine detoxification ability is poor, and slow to the viral hepatitis curative effect, cure rate is lower.
The objective of the invention is to utilize motherland medicine theoretical, provide a kind of reduction jaundice fast, controlling, to be auxilliary with the guarantor, medicine that can rapid Cure Viruses hepatitis.
The present invention uses Herba Artemisiae Scopariae, Radix Salviae Miltiorrhizae, Flos Lonicerae, Cordyceps, Rhizoma Imperatae, Radix Curcumae to carry out prescription, and the weight proportion of prescription is Herba Artemisiae Scopariae: 15-70 part, Radix Salviae Miltiorrhizae: 10-40 part, Flos Lonicerae: 15-50 part, Cordyceps: 2-10 part, Rhizoma Imperatae: 15-50 part, Radix Curcumae: 5-20 part.
Formula optimization weight proportion scope of the present invention is Herba Artemisiae Scopariae: 20-50 part, Radix Salviae Miltiorrhizae: 15-30 part, Flos Lonicerae: 20-40 part, Cordyceps: 4-8 part, Rhizoma Imperatae: 20-40, Radix Curcumae: 10-15 part.
Optimum weight proportioning of the present invention is Herba Artemisiae Scopariae: 30 parts, and Radix Salviae Miltiorrhizae: 25 parts, Flos Lonicerae: 20 parts, Cordyceps: 5 parts, Rhizoma Imperatae: 25 parts, Radix Curcumae: 15 parts.
In the above-mentioned prescription,, can replace with Radix Isatidis there not being the Herba Artemisiae Scopariae medical material; Radix Salviae Miltiorrhizae can replace with Radix Paeoniae Rubra, but preferably uses Radix Salviae Miltiorrhizae; Flos Lonicerae can replace with Hui Geye, but preferably uses Flos Lonicerae.On the basis of above-mentioned prescription, can also increase some accessory drugs components, as the Semen Coicis that can be added with 10-30 part (Job's tears), the Semen Coicis (Job's tears) that can be added with 15-25 part at the prescription of preferred weight proportioning can be added with 20 parts Semen Coicis (Job's tears) at the prescription of optimum weight proportioning.Drug dose of the present invention is to be the dose of oral secondary with the made dose of raw material 60-210g, sooner or later services once.General consumption is to be oral two or three times dose with the made dose of raw material 120g, as being the dose of oral secondary with the made dose of following raw materials according:
Herba Artemisiae Scopariae: 30g, Radix Salviae Miltiorrhizae: 25g, Flos Lonicerae: 20g, Cordyceps: 5g, Rhizoma Imperatae: 25g, Radix Curcumae: 15g.
Medicine of the present invention can be made into several formulations or dosage form.The fried one-tenth decoction of water, concrete manufacturing process can be earlier crude drug to be packed in the medicine pot, add half fried one-tenth medicinal liquid of Total Water, pour out medicinal liquid, 2/3rds fried one-tenth medicinal liquids of medicinal residues reuse surplus water are poured out medicinal liquid, the last decocting of medicinal residues reuse once, three times medicinal liquid mixes.The medical filtration sugaring of above-mentioned decoction can be concentrated into about the 5-25% of amount of water, make syrup preparation.This syrup preparation use amount is: every 500cc clothes six times, day clothes secondary.The medical filtration of above-mentioned decoction can be concentrated, make pill or make powdered electuary.
The present invention is nontoxic according to being slightly cold for the Herba Artemisiae Scopariae hardship is flat, and energy clearing away damp-heat, sharp jaundice have Detoxication, are the medicines that the traditional Chinese medical science is commonly used for treatment hepatitis; Radix Salviae Miltiorrhizae: bitter tepor, nontoxic, go into Liver Channel energy blood circulation promoting and blood stasis dispelling, analgesic effect is arranged; Flos Lonicerae: heat clearing and inflammation relieving; Cordyceps: sweet in the mouth is flat, tonifying deficiency is arranged, useful vital essence function of invigorating spleen; Rhizoma Imperatae: sweet in the mouth is cold, and clearing away heat and promoting diuresis, removing heat from blood, anastalsis are arranged; Radix Curcumae: the sweet-bitter flavor cold is gone into liver and gall through promoting QI circulation for relieving depression, the broken painful effect of removing heat from blood are arranged.The auxiliary Semen Coicis that adds then is the slightly sweet flavor cold, goes into the liver spleen channel, and the effect of spleen invigorating, clearing away heat-damp and promoting diuresis is arranged; The traditional Chinese medical science is thought: " disease is not understood in defending branch, and hinders to go into nutrient blood and be subjected to heresy, and its disease must be endangered ", so pathogenic factor can not be immediately from defending table, the urine discharge then certainly will be spread unchecked at internal organs.
Medicine of the present invention has heat-clearing and toxic substances removing dampness removing, jaundice eliminating, spleen invigorating, suppressing the hyperactive liver, removing heat from blood, resolving depression, beneficial vital essence function.Medicine of the present invention is compared with existing similar medicine, has at treating the liver, the intestinal that do not injure one's stomach when protecting the liver, and helps the absorption of patient to medicine, also is convenient to the recovery of patient's muscle power; Active drug enters detoxifcation in the human body, and virus is not only discharged from gastrointestinal and stool, and can discharge from urethra effectively, makes virus get rid of fast and effectively; The medicine no side effects, employed medicine raw material source is wide, cost is low; After patient takes, have the jaundice eliminating subcutaneous ulcer rapid, the sending down the abnormal ascending QI relieving distension is fast, energy appetite stimulator, short treating period, obvious effects such as cure rate height.This medical syrup has better curative effect to virus type hepatitis, and is also effective in cure to liver cirrhosis.With this medicine routine patient surplus ten thousand is treated, obvious curative effects is all arranged.
Characteristics of the present invention are that prescription is reasonable, according to the characteristics of hepatitis disease, reach to control with a little a few flavor Chinese medicine composition, and be the purpose of assisting with the guarantor, the medication uniqueness; Effect is peculiar, and a few days is just seen curative effect after patient's medication, and liver function indexes just can recover normally about one month, even also can reach the obvious treatment effect to the case of liver cirrhosis, the hepatic coma dispensing a few days.Use medicine of the present invention to take during the treatment, need not other drug.The method of utilization heat-clearing and toxic substances removing diuresis tonify deficiency makes heresy discharge from urine, does not promptly damage healthy energy, and virus is excreted very soon, and the patient is got well early.
In order to further specify the effect of medicine of the present invention, the viral hepatitis patient is compared treatment with medicine of the present invention.
One, clinical data: 160 examples are organized in treatment, male 96 examples, and women 64 examples at 18～76 years old age, have alcoholic 13 examples.Wherein, icteric index is at 6 more than the unit, 100 below the unit, and glutamate pyruvate transaminase is greater than 40 units, less than 500 units, and 80 examples are the hypopathia group; Icteric index is at 100 more than the unit, and glutamate pyruvate transaminase is greater than 500 units, and 80 examples are the severe disease group.Matched group provides clinical observation material 40 examples by infectious hospital, wherein male 21 examples, and women 19 examples, average 43 years old, there were alcoholic 2 examples at the age at 21～65 years old.Icteric index is at 6 more than the unit, 100 below the unit, and glutamate pyruvate transaminase is greater than 40 units, less than 500 units, and 20 examples are the hypopathia group; Icteric index is at 100 more than the unit, and glutamate pyruvate transaminase is greater than 500 units, and 20 examples are the severe disease group.The patient surface antigen HBsAg of treatment group and matched group is positive.
Two, Therapeutic Method:
The treatment group is formed with the decoction of the liver benefiting jaundice eliminating medicine of the present invention, its medicine: Herba Artemisiae Scopariae, Radix Salviae Miltiorrhizae, Flos Lonicerae, Cordyceps, Rhizoma Imperatae, Radix Curcumae; The matched group Herba Artemisiae Scopariae Decoction, its medicine is formed: Herba Artemisiae Scopariae, Radix Et Rhizoma Rhei, Fructus Gardeniae.All take by the general dose of decoction of Chinese patent medicine, service once every day sooner or later, and a week is the course of treatment that treatment detects.
Three, therapeutic outcome:
1, criterion of therapeutical effect
Cure: the clinical symptoms complete obiteration, liver function recovery is normal, and icteric index drops to 6 below the unit, and the transaminase is at 40 below the unit, and surface antigen HBsAg is negative.The study of patient's operate as normal.
Produce effects: liver function is normal, sx, and icteric index and transaminase descend to some extent, do not reach the healing index, and surface antigen HBsAg is negative, and chance feelings will causes change and can bring out, and the study of resuming work substantially can be cured if continue treatment.
Invalid: symptom is not improved, abnormal liver function, cisco unity malfunction, study.
2, therapeutic outcome: see Table 1,2
Table 1
Glutamate pyruvate transaminase treatment back HBsAg in icteric index treatment back behind the GP TH
The hypopathia group after one week less than after one week of 6 units less than 40 units treatment group after three months
The severe disease group after one week less than after one week of 80 units less than 400 unit negative conversion rates 89%
After two weeks less than after two weeks of 6 units less than 40 units
Drop to one week of hypopathia group 10% and drop to 40 units treatment group one week of 6 units 10% after three months
The severe disease group after two weeks greater than after two weeks of 80 units greater than 400 unit negative conversion rates 0
Table 2
| Grouping | The example number | HBsAg cures the invalid total effective rate of produce effects before and after the treatment |
| The treatment group | 160 examples | 89% sun turns out cloudy 89% 100% 0 100% |
| Matched group | 40 examples | Negative conversion rate is 0 5% 12.5% 87.5% 12.5% |
Four, case
Case (1)
The Wang, woman, 32 years old, in early June, 1994, aversion to cold, heating, whole body appearance jaundice lasts three days, checks liver function glutamate pyruvate transaminase＞400 units, icteric index 120 units, be diagnosed as acute icterohepatitis income infectious hospital, the liver protecting therapy of being infused, the state of an illness is not seen and is alleviated, jaundice is deepened day by day, and refreshing fan is drowsiness.Change the decoction of taking the liver benefiting jaundice eliminating medicine of the present invention, after three doses, the gastral cavity abdomen is happy, and spirit is relaxed and comfortable, thinks hungry desire food after obeying three doses again.State of an illness trend is stable after taking a week, check liver function, icteric index 20 units, glutamate pyruvate transaminase 50 units, Moschus moschiferous turbidity 12 units, Moschus moschiferous wadding degree 12 units; Take icteric index 6 units after two weeks, glutamate pyruvate transaminase 40 units, Moschus moschiferous turbidity 6 units, Moschus moschiferous wadding degree 6 units continue to take the liver benefiting jaundice eliminating soup first quarter moon, and three checks of liver function are all normal, resume work after two months, follow up a case by regular visits to gun-ho 2 years.This jaundice diminishing medicine good for liver decoction is by Herba Artemisiae Scopariae 5Kg, and Radix Salviae Miltiorrhizae 2.5Kg, Flos Lonicerae 5Kg, Cordyceps 1Kg, Rhizoma Imperatae 3Kg, Radix Curcumae 1.5Kg add decocting system.Be divided into 100 doses altogether, take potion every day, divide sooner or later to take potion twice.
Case (2)
Grandson, man, 45 years old, certain government functionary, first visit mid-March nineteen ninety-five, readme before 2 years health check-up find to suffer from and to recall type hepatitis, usual fatigue and weak, distending pain in the hypochondrium does not relax, and emotion is emotional, obey the Chinese medicine and western medicine symptom and do not see improvement, this morbidity is got angry because of anger and is brought out, and the body icteric sclera dyes, and accompanies the superfluous breast side of body to produce full, abdominal distension and anorexia, fatigue and weakness.Be in hospital in local hospital before five days, oral liver Thailand washes one's hair, and vitamin also adds the Radix Salviae Miltiorrhizae Injection intravenous drip with 10% G/W, and jaundice is deepened gradually after five days, enlarged abdomen, and oliguria with reddish urine, stool closes knot, down in spirits.Seek medical advice, check liver function: Moschus moschiferous turbidity 10 units, Moschus moschiferous wadding degree 18 units, glutamate pyruvate transaminase＞500 units, icteric index 406 units, 11.2 milligrams of % of total bilirubin, alkali phosphatase 35 units, anti--HBC (+); HBsAg (+); Be diagnosed as serious symptom and recall type hepatitis, concurrent ascites, the state of an illness are very serious.After taking three doses of jaundice diminishing medicine good for liver decoctions, convenient to both passing unimpeded, pine subtracts abdominal distention.Behind the fortnight of taking medicine, ascites disappears, check liver function, Moschus moschiferous turbidity 8 units, Moschus moschiferous turbidity 10 units, glutamate pyruvate transaminase 128 units, icteric index 200 units, 2.1 milligrams of % of total bilirubin, alkali phosphatase 18 units.Continue to take one week of the liver benefiting jaundice eliminating decoction, Moschus moschiferous turbidity 6 units, Moschus moschiferous turbidity 6 units, glutamate pyruvate transaminase 80 units, icteric index 80 units.Continue to take one week of the liver benefiting jaundice eliminating decoction, Moschus moschiferous turbidity 6 units, Moschus moschiferous turbidity 6 units, glutamate pyruvate transaminase are less than 40 units, and icteric index is less than 6 units, and jaundice is moved back only, and the food of sleeping all can.After serveing on three months, liver function is normal, clinical symptom disappearance, and HBsAg (-), anti--HBC (-), recovery from illness working work is followed up a case by regular visits to so far, not recurrence again.This jaundice diminishing medicine good for liver decoction is by Herba Artemisiae Scopariae 7Kg, and Radix Salviae Miltiorrhizae 3.5Kg, Flos Lonicerae 1.5Kg, Cordyceps 0.2Kg, Rhizoma Imperatae 4Kg, Radix Curcumae 2Kg add decocting system.Be divided into 100 doses altogether, take potion every day, divide sooner or later to take potion twice.
Further specify the present invention below in conjunction with example.
Example 1, the liver benefiting jaundice eliminating syrup formula are:
Herba Artemisiae Scopariae 1500g, Radix Salviae Miltiorrhizae 1000g, Flos Lonicerae 1000g, Semen Coicis 1000g, Cordyceps 150g, Rhizoma Imperatae 1000g, Radix Curcumae 500g.
It is fried into about the 12.5kg medicinal liquid that above-mentioned Chinese medicine adding decocting medicine pot is added water 30kg post-heating.After leaching medicinal liquid, add 20kg water again and go into decocting medicine pot, fry in shallow oil medicinal liquid into about 10kg.After leaching medicinal liquid, leach into about the 5kg medicinal liquid with the 12.5kg decocting.Three times medicinal liquid merges about 27.5kg, adds white sugar 1.5kg and is concentrated into 15kg, bottling, every bottle of 500cc.
The Wang, the woman 26 years old, suffers from one week of acute icterohepatitis, liver function, Moschus moschiferous 14 units of wadding a quilt with cotton; Glutamate pyruvate transaminase 148 units; Icteric index 40 units, between the Fan Dengbaishi reaction +++, straight +++, surface antigen (+), clothes the liver benefiting jaundice eliminating syrup; Day obeys three times, each 35cc, and liver power checking is all normal after 15 days.
Example 2,
Use Herba Artemisiae Scopariae 4000g, Radix Salviae Miltiorrhizae 2500g, Flos Lonicerae 2000g, Cordyceps 500g, Rhizoma Imperatae 2500g, the raw material of Radix Curcumae 1500g make the liver benefiting jaundice eliminating syrup medicine.The fried one-tenth decoction of raw material water is concentrated into the medical filtration sugaring of decoction about the 5-25% of amount of water, makes syrup preparation.This syrup preparation use amount is: every 500cc clothes six times, day clothes three times.
In certain, the man, 34 years old, the intensification of carrying out property of jaundice was in hospital with hepatitis gravis in 1992.Yellowish body such as gold are accompanied superfluous ascites, the mind unconsciousness.The inspection liver function is extremely damaged, and gallbladder enzyme segregation phenomenon occurs, and the state of an illness is very serious, takes the liver benefiting jaundice eliminating syrup, and patient's mental status is good after 3 days, and icteric index descends greatly after 10 days, serve on ascites on the 30th and disappears, and liver function index is all normal.
Example 3, get Herba Artemisiae Scopariae 35Kg, Radix Salviae Miltiorrhizae 20Kg, Flos Lonicerae 15Kg, Cordyceps 5Kg, Semen Coicis 20Kg, Rhizoma Imperatae 20Kg, Radix Curcumae 20Kg, the fried one-tenth decoction of water concentrates decoction the pill medicine of making 1000 balls.As the medicine commonly used of viral hepatitis, half ball is oral amount once, according to the difference of sick weight, can be divided into day clothes once or secondary or three times.
Claims (6)
1, a kind of jaundice diminishing medicine good for liver is to be the Chinese medicine of principal agent treatment viral hepatitis with the Herba Artemisiae Scopariae, it is characterized in that it is made by following component:
Herba Artemisiae Scopariae 15-70 part,
Radix Salviae Miltiorrhizae 10-40 part,
Flos Lonicerae 15-50 part,
Cordyceps 2-10 part,
Rhizoma Imperatae 15-50 part,
Radix Curcumae 5-20 part.
2,, it is characterized in that the weight portion of each component is as the said jaundice diminishing medicine good for liver of claim 1:
Herba Artemisiae Scopariae 20-50 part,
Radix Salviae Miltiorrhizae 15-30 part,
Flos Lonicerae 20-40 part,
Cordyceps 4-8 part,
Rhizoma Imperatae 20-40 part,
Radix Curcumae 10-15 part.
3,, it is characterized in that the weight portion of each component is as the said jaundice diminishing medicine good for liver of claim 2:
30 parts of Herba Artemisiae Scopariaes,
25 parts of Radix Salviae Miltiorrhizaes,
20 parts of Flos Loniceraes,
5 parts of Cordyceps,
25 parts of Rhizoma Imperataes,
15 parts of Radix Curcumaes.
4, as claim 1 or 2 or 3 said jaundice diminishing medicine good for liver, it is characterized in that: the Semen Coicis that is added with 10-30 part.
5, as the said jaundice diminishing medicine good for liver of claim 2, it is characterized in that: the Semen Coicis that is added with 15-25 part.
6, as the said jaundice diminishing medicine good for liver of claim 3, it is characterized in that: the Semen Coicis that is added with 20 parts.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98113763A CN1062765C (en) | 1998-02-12 | 1998-02-12 | Jaundice diminishing medicine good for liver |
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| Application Number | Priority Date | Filing Date | Title |
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| CN98113763A CN1062765C (en) | 1998-02-12 | 1998-02-12 | Jaundice diminishing medicine good for liver |
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| CN1225830A CN1225830A (en) | 1999-08-18 |
| CN1062765C true CN1062765C (en) | 2001-03-07 |
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| CN98113763A Expired - Fee Related CN1062765C (en) | 1998-02-12 | 1998-02-12 | Jaundice diminishing medicine good for liver |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1923264B (en) * | 2006-08-02 | 2010-05-12 | 福建广生堂药业有限公司 | Capsule comprising artemisia capillaries and rhizoma imperatae for treating hepatitis |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1100642A (en) * | 1993-09-22 | 1995-03-29 | 李彤 | Traditional Chinese medicine prepn. for curing B-hepatitis |
| CN1113779A (en) * | 1994-06-17 | 1995-12-27 | 殷广全 | Anti- hepatitis B preparation |
| CN1160562A (en) * | 1996-03-26 | 1997-10-01 | 雷东明 | Chinese herbal medicine for curing hepatitis |
| CN1166342A (en) * | 1996-05-27 | 1997-12-03 | 刘智华 | Chinese medicine preparation for hepatosis |
| CN1171257A (en) * | 1996-07-19 | 1998-01-28 | 郑先兵 | Chinese-herbal medicine for curing hepatitis B and its preparing process |
-
1998
- 1998-02-12 CN CN98113763A patent/CN1062765C/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1100642A (en) * | 1993-09-22 | 1995-03-29 | 李彤 | Traditional Chinese medicine prepn. for curing B-hepatitis |
| CN1113779A (en) * | 1994-06-17 | 1995-12-27 | 殷广全 | Anti- hepatitis B preparation |
| CN1160562A (en) * | 1996-03-26 | 1997-10-01 | 雷东明 | Chinese herbal medicine for curing hepatitis |
| CN1166342A (en) * | 1996-05-27 | 1997-12-03 | 刘智华 | Chinese medicine preparation for hepatosis |
| CN1171257A (en) * | 1996-07-19 | 1998-01-28 | 郑先兵 | Chinese-herbal medicine for curing hepatitis B and its preparing process |
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