CN106266448A - A kind of biologic enzyme preventing and treating alopecia agent - Google Patents

A kind of biologic enzyme preventing and treating alopecia agent Download PDF

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Publication number
CN106266448A
CN106266448A CN201610665579.2A CN201610665579A CN106266448A CN 106266448 A CN106266448 A CN 106266448A CN 201610665579 A CN201610665579 A CN 201610665579A CN 106266448 A CN106266448 A CN 106266448A
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ferment
enzyme
chinese medicine
medicine additive
alopecia
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黄剑忠
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Priority to CN201610665579.2A priority Critical patent/CN106266448A/en
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Priority to PCT/CN2017/085016 priority patent/WO2018032835A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535—Perilla (beefsteak plant)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732—Chaenomeles, e.g. flowering quince
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Inorganic Chemistry (AREA)
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  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

One biologic enzyme of the present invention preventing and treating alopecia agent, relates to a kind of alopecia control agent, particularly relates to enzyme preventing and treating alopecia agent, and its feature exists: include enzyme ferment and Chinese medicine additive two composition；Described enzyme ferment uses following material to ferment by weight proportion and forms, after enzyme ferment completes, through decontamination → clear liquor → natural stabiliser → eluting filtrate, being eventually adding Chinese medicine additive, enzyme ferment is 9:1 with the part by weight of Chinese medicine additive.The present invention has a significant preventive and therapeutic effect to seborrheic alopecia and psychogenic alopecia syndrome, concrete Anti-hair loss and help effect of hair growth promoting, and has no side effect.

Description

A kind of biologic enzyme preventing and treating alopecia agent
Technical field
The present invention relates to a kind of alopecia control agent, particularly relate to enzyme preventing and treating alopecia agent.
Background technology
The type of alopecia is divided into two big classes: (1) psychogenic alopecia, (2) seborrheic alopecia, seborrheic alopecia is also known as seborrheica Alopecia, man's androgen source property alopecia or hereditary alopecia are a kind of permanent alopecias, along with present rhythm of life is accelerated, pressed Power anxiety excessive, long-term, anxiety, tired problem, the problem of seborrheic alopecia rejuvenation is day by day serious, and seborrheic alopecia with Psychogenic alopecia syndrome, more difficult with preventing and treating in treatment, except traditional treatment by Chinese herbs, also Western medicine Drug therapy, but It is that the effect of both medicines often cannot be entirely satisfactory, along with the development of bioscience, hair grafting technology, technology also occurs Need cut flap at donor, so rear cranial nerve can be injured cause some postoperative sequela.
Summary of the invention
The present invention has a significant preventive and therapeutic effect to seborrheic alopecia and psychogenic alopecia syndrome, concrete Anti-hair loss and help life The effect sent out, and have no side effect.
For achieving the above object, the present invention is by the following technical solutions: include enzyme ferment and Chinese medicine additive two Portion forms；
Described enzyme ferment uses following material to ferment by weight proportion and forms:
Water 60-75 part, remelt sugar 6-8 part, Poria 1-3 part, Rohdea japonica Roth 2-5 part, Fructus Chaenomelis 1-5 part, Flos Lonicerae 2-6 part, camellia oleosa seed 3-8 part, Folium Perillae 2-3 part, Fructus Citri Sarcodactylis 1-6 part, Fructus Citri Limoniae 1-2 part；
Remelt sugar is first poured into water stirring melt, then surplus material is dipped among sucrose solution more than ferment half a year, period Note ventilated, avoid sunlight；
Described Chinese medicine additive uses following material the most formulated；
Radix Polygoni Multiflori 16-38 part, germanite 2-9 part, Fructus Schisandrae Chinensis 5-16 part, Rhizoma Polygoni Cuspidati 2-7 part, Endothelium Corneum Gigeriae Galli 3-8 part, Fructus Lycii 12-26 Part, Rhizoma Dioscoreae 5-11 part；
After enzyme ferment completes, through decontamination → clear liquor → natural stabiliser → eluting filtrate, finally Adding Chinese medicine additive, enzyme ferment is 9:1 with the part by weight of Chinese medicine additive.
Enzyme ferment is the necessary thing of human metabolism's process, has more than 5000 kind of enzyme ferment to participate among human body Metabolism could maintain healthy health, when certain part biological enzyme ferment is not enough or too much, will affect health part organ Function, either seborrheic alopecia or psychogenic alopecia are all that enzymes metabolism system goes wrong.
Rat is utilized to have a fiery temperament, it is easy to the feature enraged, according to enraging the method for stimulation by male for Wistar cleaning grade Rat sets up animal model, and its heart stomach function regulating motion frequency, amplitude are carried out testing inspection.Experimental result shows, its heart stomach function regulating Mechanical Contraction frequency, shrinkage amplitude aspect the most substantially reduces, thus illustrates that the present invention is to suppression anxiety, anxiety, fidgety etc. Unhealthy emotion has significantly effect
So supplementing or the enzyme ferment of balanced human, then add the nutrient of Chinese medicine to seborrheic alopecia and spirituality Alopecia syndrome has significant preventive and therapeutic effect, has Anti-hair loss and helps effect of hair growth promoting, and having no side effect.
Detailed description of the invention
A kind of biologic enzyme preventing and treating alopecia agent includes: described enzyme ferment uses following material to send out by weight proportion Ferment forms:
71 parts of water, remelt sugar 7 parts, 1.5 parts of Poria, Rohdea japonica Roth 3 parts, Fructus Chaenomelis 2 parts, Flos Lonicerae 3 parts, camellia oleosa seed 5 parts, Folium Perillae 2.3 parts, Fructus Citri Sarcodactylis 4 parts, 1.2 parts of Fructus Citri Limoniae；
Remelt sugar is first poured into water stirring melt, then surplus material is dipped among sucrose solution more than ferment half a year, period Note ventilated, avoid sunlight；
Described Chinese medicine additive uses following material the most formulated；
The Radix Polygoni Multiflori 36 parts, germanite 8 parts, Fructus Schisandrae Chinensis 13 parts, Rhizoma Polygoni Cuspidati 5 parts, Endothelium Corneum Gigeriae Galli 6 parts, Fructus Lycii 22 parts, Rhizoma Dioscoreae 10 parts；
After enzyme ferment completes, through decontamination → clear liquor → natural stabiliser → eluting filtrate, finally Adding Chinese medicine additive, enzyme ferment is 9:1 with the part by weight of Chinese medicine additive.
Enzyme ferment is the necessary thing of human metabolism's process, has more than 5000 kind of enzyme ferment to participate among human body Metabolism could maintain healthy health, when certain part biological enzyme ferment is not enough or too much, will affect health part organ Function, either seborrheic alopecia or psychogenic alopecia are all that enzymes metabolism system goes wrong, thus supplement or balance people The enzyme ferment of body adds Chinese medicine again, nutrient seborrheic alopecia and psychogenic alopecia syndrome had significantly prevent and treat work With, there is Anti-hair loss and help effect of hair growth promoting, and having no side effect.
Last it is noted that obviously, above-described embodiment is only for clearly demonstrating example of the present invention, and not Restriction to embodiment.For those of ordinary skill in the field, can also make on the basis of the above description The change of other multi-form or variation.Here without also cannot all of embodiment be given exhaustive.And thus amplified Go out obviously changes or changes among still in protection scope of the present invention.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all essences in the present invention Any amendment, equivalent and the improvement etc. made within god and principle, should be included within the scope of the present invention.

Claims (1)

1. a biologic enzyme preventing and treating alopecia agent, its feature exists: include enzyme ferment and Chinese medicine additive two composition；
Described enzyme ferment uses following material to ferment by weight proportion and forms:
Water 60-75 part, remelt sugar 6-8 part, Poria 1-3 part, Rohdea japonica Roth 2-5 part, Fructus Chaenomelis 1-5 part, Flos Lonicerae 2-6 part, camellia oleosa seed 3-8 Part, Folium Perillae 2-3 part, Fructus Citri Sarcodactylis 1-6 part, Fructus Citri Limoniae 1-2 part；
Remelt sugar being first poured into water stirring melt, then surplus material is dipped among sucrose solution more than ferment half a year, period notes Ventilated, avoid sunlight；
Described Chinese medicine additive uses following material the most formulated；
Radix Polygoni Multiflori 16-38 part, germanite 2-9 part, Fructus Schisandrae Chinensis 5-16 part, Rhizoma Polygoni Cuspidati 2-7 part, Endothelium Corneum Gigeriae Galli 3-8 part, Fructus Lycii 12-26 part, mountain Medicine 5-11 part；
After enzyme ferment completes, through decontamination → clear liquor → natural stabiliser → eluting filtrate, it is eventually adding Chinese medicine additive, enzyme ferment is 9:1 with the part by weight of Chinese medicine additive.
CN201610665579.2A 2016-08-13 2016-08-13 A kind of biologic enzyme preventing and treating alopecia agent Withdrawn CN106266448A (en)

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CN201610665579.2A CN106266448A (en) 2016-08-13 2016-08-13 A kind of biologic enzyme preventing and treating alopecia agent
PCT/CN2017/085016 WO2018032835A1 (en) 2016-08-13 2017-05-19 Agent for preventing and treating alopecia by biological ferment

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Application Number Priority Date Filing Date Title
CN201610665579.2A CN106266448A (en) 2016-08-13 2016-08-13 A kind of biologic enzyme preventing and treating alopecia agent

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018032835A1 (en) * 2016-08-13 2018-02-22 谭华锋 Agent for preventing and treating alopecia by biological ferment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101254274B (en) * 2008-03-27 2012-11-07 李洪元 Nano Chinese medicinal composition for curing white hair alopecia
CN104013947A (en) * 2014-06-27 2014-09-03 喻朝阳 Hair-restorer spraying liquid of fresh medicine, fruit and vegetable ferments with effects of preventing hair loss and restoring hair and preparation method thereof
CN105380899A (en) * 2015-12-27 2016-03-09 泉州市简能环保科技有限公司 Traditional Chinese medicine enzyme shampoo and preparing method thereof
CN106110037A (en) * 2016-08-13 2016-11-16 黄剑忠 A kind of Chinese medicine ferment balancing male 5 alpha-reductase
CN106266448A (en) * 2016-08-13 2017-01-04 黄剑忠 A kind of biologic enzyme preventing and treating alopecia agent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018032835A1 (en) * 2016-08-13 2018-02-22 谭华锋 Agent for preventing and treating alopecia by biological ferment

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