CN106110037A - A kind of Chinese medicine ferment balancing male 5 alpha-reductase - Google Patents

A kind of Chinese medicine ferment balancing male 5 alpha-reductase Download PDF

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CN106110037A
CN106110037A CN201610665049.8A CN201610665049A CN106110037A CN 106110037 A CN106110037 A CN 106110037A CN 201610665049 A CN201610665049 A CN 201610665049A CN 106110037 A CN106110037 A CN 106110037A
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parts
ferment
chinese medicine
radix
alopecia
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黄剑忠
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Priority to PCT/CN2017/085031 priority patent/WO2018032838A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533—Leonurus (motherwort)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998—Hordeum (barley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Abstract

A kind of Chinese medicine ferment balancing male 5 alpha-reductase of the present invention, relates to a kind of alopecia control agent, particularly relates to enzyme preventing and treating alopecia agent, and its feature exists: is added in the ratio of 2:8 by microbial enzyme ferment and is mixed and made into Chinese medicine ferment among Chinese medicine extract；Microbial enzyme ferment is formed by water, brown sugar, Poria, Rohdea japonica Roth, camellia oleosa seed, rice vinegar, Hericium erinaceus (Bull. Ex Fr.) Pers., Sargassum part, the fermentation of pinaster juice, and Chinese medicine extract is mixed by weight proportion by Semen Nelumbinis, Rhizoma Zingiberis Recens, Fructus Crataegi, Fructus Hordei Germinatus, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Herba Lycopi, Herba Leonuri, Radix Arnebiae (Radix Lithospermi), the water extract of Radix Angelicae Sinensis；The present invention is by Chinese medicine and ferment regulation taste hepatic and renal function and the androgen secretion of balanced human, thus 5 alpha-reductases are balanced, the problem basically solving seborrheic alopecia.

Description

A kind of Chinese medicine ferment balancing male's 5α-reductase
Technical field
The present invention relates to a kind of alopecia control agent, particularly relate to enzyme preventing and treating alopecia agent.
Background technology
Seborrheic alopecia (sebrrheic alopecia, S A), has another name called male pattern alopecia (male Patternalopecia, MPA), androgenetic alopecia (Androgenetic alopecia, AGA), multiple be born in, blue or green Year male, 25～the alopecia that there are about 1/3 generation in adult male in various degree in 40 years old.Although patient is without obvious subjective symptoms, but An urgent demand treatment because shadow is attractive in appearance.
Head hair is strictly affected by androgen, and androgen main in males is testosterone, can be at 5 α-also It is metabolized into dihydrotestosterone (Dihydrotestosterone, DHT) under the effect of protoenzyme (5 α-R).And DHT causes alopecia Main cause, it can be combined with intracellular receptor protein, transfer in nucleus, by specific gene activation, induction life Become specific protein, thus hinder the growth of hair, and then produce permanent alopecia or alopecia.Man's alopecia is plainly It is exactly that DHT secretion is excessive, causes skin to secrete oils and fats in a large number, containing a kind of material being 5α-reductase in oils and fats, this material Can swallow, block hair follicle, cause alopecia.DHT plays an important role in SA, by suppression 5α-reductase activity i.e. DHT can be suppressed to synthesize, thus reach the purpose of Anti-hair loss.The at present suppression to 5α-reductase activity mainly use finasteride, The western medicine compositions such as epristeride, epristeride, dutasteride, but western medicine composition zest is big, side effect big, as finasteride is secondary The meeting of effect causes the symptom that male's hyposexuality, sexual impotence, ejaculation amount reduce；Epristeride side effect causes feeling sick, has a sleepless night, head Dusk, the symptom of erection disturbance, do not enumerate.
China is also little about the article of the microbe species in ferment and quantity, and the production technology of ferment product is mostly Japan Patent, brings a high price the most at home, it is therefore desirable to active development has the Technology of independent intellectual property right, raw to reduce Produce cost.
Summary of the invention
The present invention by Chinese medicine and ferment regulation taste hepatic and renal function and the androgen secretion of balanced human, thus 5 α-also Protoenzyme is balanced, the problem basically solving seborrheic alopecia.
For achieving the above object, the present invention is by the following technical solutions: in being added in the ratio of 2:8 by microbial enzyme ferment Chinese medicine ferment it is mixed and made among medicament extract；
Described microbial enzyme ferment uses following material to ferment by weight proportion and forms:
Water 50～71 parts, brown sugar 7～11 parts, Poria 8～12 parts, Rohdea japonica Roth 5～6 parts, camellia oleosa seed 13～15 parts, rice vinegar 5～9 Part, Hericium erinaceus (Bull. Ex Fr.) Pers. 7～9 parts, Sargassum 2～6 parts, pinaster juice 3～5 parts；
Fermentation method: first brown sugar is poured into water stirring melt, then by Poria, Rohdea japonica Roth, camellia oleosa seed, rice vinegar, Hericium erinaceus (Bull. Ex Fr.) Pers., Sargassum is dipped among sucrose solution more than ferment half a year, puts down pinaster juice ferment in second time the most again more than two months, the temperature of fermentation Spend 32～38 DEG C, pH value 6.0, period note ventilated, avoid sunlight；
Described Chinese medicine extract uses the water extract of following material to mix by weight proportion:
Semen Nelumbinis 5～8 parts, Rhizoma Zingiberis Recens 8～12 parts, Fructus Crataegi 7～13 parts, Fructus Hordei Germinatus 3～6 parts, Radix Paeoniae Rubra 6～9 parts, Radix Achyranthis Bidentatae 9～15 parts, Herba Lycopi 1～2 parts, Herba Leonuri 4～8 parts, Radix Arnebiae (Radix Lithospermi) 3～8 parts, Radix Angelicae Sinensis 8～18 parts.
Enzyme ferment is the necessary thing of human metabolism's process, has more than 5000 kind of enzyme ferment to participate among human body Metabolism could maintain healthy health, when certain part biological enzyme ferment is not enough or too much, will affect human body to specific battalion Form part picked-up, help human body that the nutrition of Chinese medicine and food is absorbed by ferment, regulate taste hepatic and renal function, balance people The androgen secretion of body, thus 5α-reductase is balanced, the problem basically solving seborrheic alopecia.
Detailed description of the invention
The Chinese medicine ferment of a kind of male's of balance 5α-reductase includes: in being added in the ratio of 2:8 by microbial enzyme ferment Chinese medicine ferment it is mixed and made among medicament extract；
Described microbial enzyme ferment uses following material to ferment by weight proportion and forms:
63 parts of water, 9 parts of brown sugar, 9 parts of Poria, Rohdea japonica Roth 5 parts, camellia oleosa seed 14 parts, rice vinegar 7 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 8 parts, Sargassum 5 parts, Pinaster juice 4 parts；
Fermentation method: first brown sugar is poured into water stirring melt, then by Poria, Rohdea japonica Roth, camellia oleosa seed, rice vinegar, Hericium erinaceus (Bull. Ex Fr.) Pers., Sargassum is dipped among sucrose solution more than ferment half a year, puts down pinaster juice ferment in second time the most again more than two months, the temperature of fermentation Spend 37 DEG C, pH value 6.0, period note ventilated, avoid sunlight；
Described Chinese medicine extract uses the water extract of following material to mix by weight proportion:
6 parts of Semen Nelumbinis, 9 parts of Rhizoma Zingiberis Recens, Fructus Crataegi 9 parts, 4 parts of Fructus Hordei Germinatus, Radix Paeoniae Rubra 8 parts, Radix Achyranthis Bidentatae 11 parts, Herba Lycopi 2 parts, Herba Leonuri 6 parts, purple Grass 5 parts, Radix Angelicae Sinensis 12 parts.
Enzyme ferment is the necessary thing of human metabolism's process, has more than 5000 kind of enzyme ferment to participate among human body Metabolism could maintain healthy health, when certain part biological enzyme ferment is not enough or too much, will affect human body to specific battalion Form part picked-up, help human body that the nutrition of Chinese medicine and food is absorbed by ferment, regulate taste hepatic and renal function, balance people The androgen secretion of body, thus 5α-reductase is balanced, the problem basically solving seborrheic alopecia.
Last it is noted that obviously, above-described embodiment is only for clearly demonstrating example of the present invention, and not Restriction to embodiment.For those of ordinary skill in the field, can also make on the basis of the above description The change of other multi-form or variation.Here without also cannot all of embodiment be given exhaustive.And thus amplified Go out obviously changes or changes among still in protection scope of the present invention.

Claims (1)

1. balancing a Chinese medicine ferment for male's 5α-reductase, its feature exists: added in the ratio of 2:8 by microbial enzyme ferment Chinese medicine ferment it is mixed and made among Chinese medicine extract；
Described microbial enzyme ferment uses following material to ferment by weight proportion and forms:
Water 50～71 parts, brown sugar 7～11 parts, Poria 8～12 parts, Rohdea japonica Roth 5～6 parts, camellia oleosa seed 13～15 parts, rice vinegar 5～9 parts, Hericium erinaceus (Bull. Ex Fr.) Pers. 7～9 parts, Sargassum 2～6 parts, pinaster juice 3～5 parts；
The method of fermentation: first brown sugar is poured into water stirring and melts, then by Poria, Rohdea japonica Roth, camellia oleosa seed, rice vinegar, Hericium erinaceus (Bull. Ex Fr.) Pers., Sargassum It is dipped among sucrose solution more than ferment half a year, puts down pinaster juice ferment in second time the most again more than two months, the temperature 32 of fermentation ～38 DEG C, pH value 6.0, period note ventilated, avoid sunlight；
Described Chinese medicine extract uses the water extract of following material to mix by weight proportion:
Semen Nelumbinis 5～8 parts, Rhizoma Zingiberis Recens 8～12 parts, Fructus Crataegi 7～13 parts, Fructus Hordei Germinatus 3～6 parts, Radix Paeoniae Rubra 6～9 parts, Radix Achyranthis Bidentatae 9～15 parts, Herba Lycopi 1～2 part, Herba Leonuri 4～8 parts, Radix Arnebiae (Radix Lithospermi) 3～8 parts, Radix Angelicae Sinensis 8～18 parts.
CN201610665049.8A 2016-08-13 2016-08-13 A kind of Chinese medicine ferment balancing male 5 alpha-reductase Withdrawn CN106110037A (en)

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PCT/CN2017/085031 WO2018032838A1 (en) 2016-08-13 2017-05-19 Traditional chinese medicine enzyme for equilibrating male 5α-reductase

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018032835A1 (en) * 2016-08-13 2018-02-22 谭华锋 Agent for preventing and treating alopecia by biological ferment
WO2018032838A1 (en) * 2016-08-13 2018-02-22 谭华锋 Traditional chinese medicine enzyme for equilibrating male 5α-reductase
CN108186443A (en) * 2018-02-23 2018-06-22 广州市骄子日化有限公司 A kind of shampoo of blackening hair and preparation method thereof
CN110693016A (en) * 2019-11-08 2020-01-17 易大发 Tea seed shell enzyme and preparation method thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1087267A (en) * 1992-11-23 1994-06-01 梅晓春 A kind of prescription for the treatment of seborrheic alopecia
CN100522221C (en) * 2007-02-14 2009-08-05 田瑞琴 Traditional Chinese medicine pilatory
CN102755605A (en) * 2012-06-27 2012-10-31 张劲松 Hair-loss prevention traditional Chinese medicine
CN104784671A (en) * 2015-05-12 2015-07-22 刘庆芳 Formula for accelerating hair growth
CN105194607A (en) * 2015-09-22 2015-12-30 李碧红 Traditional Chinese medicine enzyme hair growth promoting liquid and preparation method thereof
CN105687520A (en) * 2016-02-22 2016-06-22 霸州市巨隆生物科技有限公司 Hair nurturing liquid for inhibiting hair loss and white hair and promoting hair growth and preparation method
CN106110037A (en) * 2016-08-13 2016-11-16 黄剑忠 A kind of Chinese medicine ferment balancing male 5 alpha-reductase

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018032835A1 (en) * 2016-08-13 2018-02-22 谭华锋 Agent for preventing and treating alopecia by biological ferment
WO2018032838A1 (en) * 2016-08-13 2018-02-22 谭华锋 Traditional chinese medicine enzyme for equilibrating male 5α-reductase
CN108186443A (en) * 2018-02-23 2018-06-22 广州市骄子日化有限公司 A kind of shampoo of blackening hair and preparation method thereof
CN110693016A (en) * 2019-11-08 2020-01-17 易大发 Tea seed shell enzyme and preparation method thereof

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