CN106265325A - A kind of skin care compositions treating infant eczema - Google Patents
A kind of skin care compositions treating infant eczema Download PDFInfo
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Abstract
The invention discloses a kind of skin care compositions treating infant eczema, mainly include the component of following mass parts: Herba Portulacae (PORTULACA OLERACEA) extract 0.1 3 parts, oligofructose 0.1 2 parts, Radix Rehmanniae (REHMANINNIA CHINENSIS) root extract 0.1 3 parts.The present invention treats the skin care compositions of infant eczema and has the mechanism of action of all-dimensional multi-angle, can realize good going eczema effect.
Description
Technical field
The present invention relates to cosmetic technical field, be specifically related to a kind of skin care compositions treating infant eczema.
Background technology
Eczema (eczema) is a kind of common epidermis caused by multiple internal and external factor and the allergic inflammation of high dermis
Disease dermatoses, with erythra multiformity, pruritus symmetrical, violent, recurrent exerbation, easily develops into chronic being characterized.Relative to
Adult, infant is easier to suffer from eczema, and its liability is closely related with skin properties.Research shows, the skin of infant is not yet
Reach maturity, functionally or structurally go up and all have very big difference with the skin being grown up.The average surface of such as infant skin
Long-pending is 2500cm2, average weight is 5kg, and the ratio of the two is 1:500；The average area of adult skin is 18000cm2, average body
Being heavily 65kg, the ratio of the two is 1:270.Infant is more than adult for the absorption of the washing product of isodose, and meanwhile, he is right
The reaction of allergin is also the most much.Therefore, baby children should be taken into full account when exploitation is for the skin-protection product of infant eczema
Youngster's skin not yet fully-developed characteristic.
After the infant that the present inventor is previously mentioned goes the numerous studies work conducted in eczema field,
It has surprisingly been found that, gentle skin protection raw material the most known per se is with the ratio in the range of determining very much
Combination, due to its significant potentiation and maintainability, the skin care compositions obtained have be obviously improved go eczema effect,
Thus complete the present invention.
Summary of the invention
Based on this, it is an object of the invention to provide a kind of skin care compositions treating infant eczema, described skin protection
Compositions has good gentleness and goes eczema effect.
In order to solve above-mentioned technical problem, the present invention is achieved through the following technical solutions:
First aspect, embodiments provides a kind of skin care compositions treating infant eczema, including following mass parts
Component: Herba Portulacae (PORTULACA OLERACEA) extract 0.1-3 part, oligofructose 0.1-2 part, Radix Rehmanniae
(REHMANINNIA CHINENSIS) root extract 0.1-3 part.Wherein in some embodiments, described treatment infant is wet
The skin care compositions of rash includes the component of following mass parts: Herba Portulacae (PORTULACA OLERACEA) extract 1.5 parts, oligomeric
1 part of fructose, Radix Rehmanniae (REHMANINNIA CHINENSIS) root extract 1.5 parts.
Further, as preferably, the skin care compositions for the treatment of infant eczema of the present invention can also be containing such as
The component of lower mass parts: Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUM ERYTHRORHIZON) extract 0.1-3 part, shaggy-fruited dittany (DICTAMNUS
DESYCARPUS) root extract 0.1-3 part.Wherein in some embodiments, the skincare composition of described treatment infant eczema
Thing includes the component of following mass parts: Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUM ERYTHRORHIZON) extract 1.5 parts, shaggy-fruited dittany
(DICTAMNUS DESYCARPUS) root extract 1.5 parts.
Further, as preferably, the skin care compositions for the treatment of infant eczema of the present invention can also contain
The component of following mass parts: pantothenylol 0.1-3 part, Aloe vulgaris (ALOE BARBADENSIS) leaf extract 0.1-3 part.
Second aspect, present invention also offers the preparation side of the skin care compositions of a kind of above-mentioned treatment infant eczema
Method, including:
1) pulverize: by Herba Portulacae, Radix Rehmanniae mixing, dry, pulverize, sieve to obtain mixed-powder；
2) extraction: being immersed in ethanol solution by mixed-powder, microwave digestion obtains lixiviating solution；
3) filter: lixiviating solution is filtered, it is thus achieved that filtrate, then filtrate is evaporated, it is thus achieved that residue；
4) dissolve: by residue water dissolution, be subsequently adding normal hexane and extract, abandon normal hexane layer, it is thus achieved that aqueous phase, centrifugal reject
Precipitation, adds oligofructose, stirring and dissolving, i.e. obtains and remove eczema Chinese medicine extract.
Wherein in some embodiments, the preparation method bag of the skin care compositions for the treatment of infant eczema of the present invention
Include:
1) pulverize: by Herba Portulacae, Radix Rehmanniae mixing, dry, pulverize, cross the screening of 50-100 eye mesh screen, prepare mixed-powder；
2) extraction: mixed-powder is immersed in (the mixed powder 6-7kg of 1kg in the ethanol solution that volume fraction is 71-75%
Ethanol solution), open frequency is microwave treatment 5-10 minute of 50KHZ, then stirring 1-2 hour, it is thus achieved that lixiviating solution；
3) filter: by lixiviating solution 400-500 mesh filter-cloth filtering, it is thus achieved that filtrate, then filtrate is evaporated, it is thus achieved that residue；
4) dissolve: by residue with water dissolution (water of the residue 20-30kg of 1kg), be subsequently adding normal hexane and carry out extracting (1kg
The normal hexane of residue 0.1-0.5kg), abandon normal hexane layer, it is thus achieved that aqueous phase, centrifugal reject precipitation, add oligofructose, stir
Mix dissolving, i.e. obtain and remove eczema Chinese medicine extract.
The third aspect, the skin care compositions for the treatment of infant eczema of the present invention has skin pruritus of releiving, redness
Deng allergic symptom, conditioning skin, enhancing skin barrier, bactericidal antiphlogistic, the all-dimensional multi-angle effect of adjustment skin Tiny ecosystem, add
Add the conventional substrate of skin care item or carrier, can be made into the cosmetics such as cream, emulsion, essence, talcum powder.
The embodiment of the present invention additionally provides a kind of baby cream, including each component of following weight/mass percentage composition: hydrogen
Change polyisobutylene 5-8%, Butyrospermum parkii (BUTYROSPERMUM PARKII) really fatty oil 1-5%, Flos Camelliae Japonicae (CAMELLIA
JAPONICA) seed oil 1-3%, Fructus oleae europaeae (OLEA EUROPAEA) fruit oil 1-2%, phytosterol 0.1-0.5%, tocopheryl acetate
Ester 0.1-1%, glyceryl stearate 0.1-0.5%, cetearyl alcohol 0.5-2%, stearic acid 0.1-0.5%, polydimethylsiloxane
1-2%, pentaerythritol stearic acid ester 2 1-2%, glycerol 5-10%, butanediol 5-10%, Sucrose Polystearic Acid Esters 0.1-0.5%, poly-second
Alkene pyrrolidone 0.1-0.5%, stearyl alcohol glycyrrhetin acid esters 0.1-0.2%, the above-mentioned skincare composition with treatment infant eczema
Thing 0.3-20%, water surplus.
Compared with prior art, the method have the advantages that
1, the skin care compositions for the treatment of infant eczema of the present invention, compounds through effective ratio science and forms, it is possible to removing heat from blood
Invigorate blood circulation, heat-clearing and toxic substances removing, skin pruritus, the redness etc. of releiving allergic symptom；The moisture needed for skin and nutrition can be supplemented, improve immunity
Power, conditioning, balance skin situation, strengthen skin barrier；The antibacterial that incidentally grows eczema, fungus etc. have the suppression of gentleness and kill
The effect of going out；Competitive inhibition pernicious bacteria, adjusts skin Tiny ecosystem.The present invention treats the skin care compositions of infant eczema to be had
The mechanism of action of all-dimensional multi-angle, can realize good going eczema effect.
2, the preparation method removing eczema Chinese medicine extract have employed extraction and method of purification, the obtained compositions of uniqueness
Middle active constituent content is high, and technique is simple, used simple equipments, it is easy to produce in enormous quantities.
3, the baby cream obtained by the present invention, has compounded Butyrospermum parkii (BUTYROSPERMUM PARKII) really fat
The vegetable oil such as oil, can form the reparation of one layer of uniform frivolous gentle oil film, beneficially skin barrier at skin surface；Have employed
The gentle emulsifying agent such as Sucrose Polystearic Acid Esters and glyceryl stearate, alleviates the emulsifying agent thorn to baby's skin to greatest extent
Swash.
Detailed description of the invention
For a more detailed description to the present invention below in conjunction with detailed description of the invention, but embodiments of the present invention are not limited to
This, for the technological parameter indicated the most especially or condition, can refer to routine techniques and carry out.
Herba Portulacae (PORTULACA OLERACEA) extract, is the extract of portulaca Herba Portulacae herb.Horse
Sativa extract has the effect of clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, antiinflammatory, can suppress il-1 (IL-1 α) inflammatory factor, has and sends out
Wave vasoconstriction effect, hypotension and reduce the function that tissue is hemorrhage, SLS(sodium lauryl sulphate can be reduced) thorn that causes
Swash and cytotoxicity.
Oligofructose, also known as fructooligosaccharide, is by β (2 1) glycosidic bond and the fruit in sucrose by 1～3 fructosyl
Glycosyl combines the mixture of ketose, C24H42 O21 and the Fructofuranosyl nystose etc. that generate.Oligofructose is a kind of wetting agent, can grow
Profit skin nutrition, is again a kind of prebiotics simultaneously, can realize the nutritive validity of competitive inhibition skin noxious bacteria, safeguard skin
Microecological environment is in health status.
Radix Rehmanniae (REHMANINNIA CHINENSIS) root extract, is the extraction of the root of Scrophulariaceae Radix Rehmanniae platymiscium Radix Rehmanniae
Thing.Radix Rehmanniae is cool in nature, sweet-bitter flavor, have enriching yin and nourishing kidney, nourish blood enrich blood, effect of removing heat from blood.
Shaggy-fruited dittany (DICTAMNUS DESYCARPUS) root extract, is the extract of Rutaceae shaggy-fruited dittany platymiscium dittany root.
Bitter in the mouth, cold in nature, there is expelling wind and removing dampness, effect of heat-clearing and toxic substances removing.
Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUM ERYTHRORHIZON) extract, is that the standard of Boraginaceae puccoon Radix Arnebiae (Radix Lithospermi) carries
Take thing.Radix Arnebiae (Radix Lithospermi) property bitter cold, removing heat from blood, invigorate blood circulation, heat clearing away, removing toxic substances, anti-inflammation, control warm macule, jaundice due to damp-heat.
Pantothenylol, the precursor of vitamin B5, wetting agent, stimulate the growth of epithelial cell, promote wound healing, play antiinflammatory and make
With.
Aloe vulgaris (ALOE BARBADENSIS) leaf extract, is the leaf of Aloeaceae aloe plant Aloe vulgaris
Standard extract.There is antipruritic, moisturizing, the skin effect of reparation.
Embodiment 1
Go the preparation of eczema Chinese medicine extract, including:
1) pulverize: by Herba Portulacae, Radix Rehmanniae (Herba Portulacae, weight ratio 0.1:3 of Radix Rehmanniae) mixing, dry, pulverize, cross 50 mesh sieves
Mesh screen divides, and prepares mixed-powder；
2) extraction: mixed-powder is immersed in the (ethanol of the mixed powder 6kg of 1kg in the ethanol solution that volume fraction is 75%
Solution), open frequency is the microwave treatment 10 minutes of 50KHZ, then stirring 1 hour, it is thus achieved that lixiviating solution；
3) filter: by lixiviating solution 500 mesh filter-cloth filterings, it is thus achieved that filtrate, then filtrate is evaporated, it is thus achieved that residue；
4) dissolve: by residue with water dissolution (water of the residue 20kg of 1kg), be subsequently adding normal hexane and carry out extracting that (1kg's is residual
The normal hexane of slag 0.5kg), abandon normal hexane layer, it is thus achieved that aqueous phase, centrifugal reject precipitation, add oligofructose, stirring and dissolving,
I.e. obtain and remove eczema Chinese medicine extract.
Embodiment 2
Go the preparation of eczema Chinese medicine extract, including:
1) pulverize: by Herba Portulacae, Radix Rehmanniae (Herba Portulacae, weight ratio 3:0.1 of Radix Rehmanniae) mixing, dry, pulverize, cross 100 mesh
Sieved through sieve, prepares mixed-powder；
2) extraction: mixed-powder is immersed in the (ethanol of the mixed powder 7kg of 1kg in the ethanol solution that volume fraction is 71%
Solution), open frequency is the microwave treatment 5 minutes of 50KHZ, then stirring 2 hours, it is thus achieved that lixiviating solution；
3) filter: by lixiviating solution 400 mesh filter-cloth filterings, it is thus achieved that filtrate, then filtrate is evaporated, it is thus achieved that residue；
4) dissolve: by residue with water dissolution (water of the residue 30kg of 1kg), be subsequently adding normal hexane and carry out extracting that (1kg's is residual
The normal hexane of slag 0.1kg), abandon normal hexane layer, it is thus achieved that aqueous phase, centrifugal reject precipitation, add oligofructose, stirring and dissolving,
I.e. obtain and remove eczema Chinese medicine extract.
Embodiment 3
Go the preparation of eczema Chinese medicine extract, including:
1) pulverize: by Herba Portulacae, Radix Rehmanniae mixing (Herba Portulacae, weight ratio 1:1 of Radix Rehmanniae), dry, pulverize, cross 80 eye mesh screens
Screening, prepares mixed-powder；
2) extraction: mixed-powder is immersed in the (second of the mixed powder 6.5kg of 1kg in the ethanol solution that volume fraction is 73%
Alcoholic solution), open frequency is the microwave treatment 8 minutes of 50KHZ, then stirring 1.5 hours, it is thus achieved that lixiviating solution；
3) filter: by lixiviating solution 450 mesh filter-cloth filterings, it is thus achieved that filtrate, then filtrate is evaporated, it is thus achieved that residue；
4) dissolve: by residue with water dissolution (water of the residue 25kg of 1kg), be subsequently adding normal hexane and carry out extracting that (1kg's is residual
The normal hexane of slag 0.3kg), abandon normal hexane layer, it is thus achieved that aqueous phase, centrifugal reject precipitation, add oligofructose, stirring and dissolving,
I.e. obtain and remove eczema Chinese medicine extract.
Embodiment 4
A kind of baby cream, including each component of following weight/mass percentage composition: Parleam 5%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) really fatty oil 5%, Flos Camelliae Japonicae (CAMELLIA JAPONICA) seed oil 1%, Fructus oleae europaeae (OLEA
EUROPAEA) fruit oil 2%, phytosterol 0.1%, tocopherol acetas 1%, glyceryl stearate 0.1%, cetearyl alcohol 2%,
Stearic acid 0.1%, polydimethylsiloxane 2%, pentaerythritol stearic acid ester 2 1%, glycerol 10%, butanediol 5%, how stearic sucrose is
Acid esters 0.5%, polyvinylpyrrolidone 0.1%, stearyl alcohol glycyrrhetin acid esters 0.2%, oligofructose 0.1%, obtained by embodiment 1
Chinese medicine extract 8%, water surplus.
Embodiment 5
A kind of baby cream, including each component of following weight/mass percentage composition: Parleam 8%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) really fatty oil 1%, Flos Camelliae Japonicae (CAMELLIA JAPONICA) seed oil 3%, Fructus oleae europaeae (OLEA
EUROPAEA) fruit oil 1%, phytosterol 0.5%, tocopherol acetas 0.1%, glyceryl stearate 0.5%, cetearyl alcohol
0.5%, stearic acid 0.5%, polydimethylsiloxane 1%, pentaerythritol stearic acid ester 2 2%, glycerol 5%, butanediol 10%, sucrose is many
Stearate 0.1%, polyvinylpyrrolidone 0.5%, stearyl alcohol glycyrrhetin acid esters 0.1%, oligofructose 2%, obtained by embodiment 2
Chinese medicine extract 0.3%, water surplus.
Embodiment 6
A kind of baby cream, including each component of following weight/mass percentage composition: Parleam 6%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) really fatty oil 3%, Flos Camelliae Japonicae (CAMELLIA JAPONICA) seed oil 2%, Fructus oleae europaeae (OLEA
EUROPAEA) fruit oil 1.5%, phytosterol 0.3%, tocopherol acetas 0.5%, glyceryl stearate 0.3%, cetearyl alcohol
1%, stearic acid 0.3%, polydimethylsiloxane 1.5%, pentaerythritol stearic acid ester 2 1.5%, glycerol 7%, butanediol 7%, sucrose
Many stearates 0.3%, polyvinylpyrrolidone 0.3%, stearyl alcohol glycyrrhetin acid esters 0.15%, oligofructose 1%, embodiment 3 institute
The Chinese medicine extract 4% prepared, water surplus.
Embodiment 7
A kind of baby cream, including each component of following weight/mass percentage composition: Parleam 6%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) really fatty oil 3%, Flos Camelliae Japonicae (CAMELLIA JAPONICA) seed oil 2%, Fructus oleae europaeae (OLEA
EUROPAEA) fruit oil 1.5%, phytosterol 0.3%, tocopherol acetas 0.5%, glyceryl stearate 0.3%, cetearyl alcohol
1%, stearic acid 0.3%, polydimethylsiloxane 1.5%, pentaerythritol stearic acid ester 2 1.5%, glycerol 7%, butanediol 7%, sucrose
Many stearates 0.3%, polyvinylpyrrolidone 0.3%, stearyl alcohol glycyrrhetin acid esters 0.15%, oligofructose 1%, Herba Portulacae
(PORTULACA OLERACEA) extract 2%, Radix Rehmanniae (REHMANINNIA CHINENSIS) root extract 2%, Radix Arnebiae (Radix Lithospermi)
(LITHOSPERMUM ERYTHRORHIZON) extract 0.1%, shaggy-fruited dittany (DICTAMNUS DESYCARPUS) root extract 3%,
Water surplus.
Embodiment 8
A kind of baby cream, including each component of following weight/mass percentage composition: Parleam 6%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) really fatty oil 3%, Flos Camelliae Japonicae (CAMELLIA JAPONICA) seed oil 2%, Fructus oleae europaeae (OLEA
EUROPAEA) fruit oil 1.5%, phytosterol 0.3%, tocopherol acetas 0.5%, glyceryl stearate 0.3%, cetearyl alcohol
1%, stearic acid 0.3%, polydimethylsiloxane 1.5%, pentaerythritol stearic acid ester 2 1.5%, glycerol 7%, butanediol 7%, sucrose
Many stearates 0.3%, polyvinylpyrrolidone 0.3%, stearyl alcohol glycyrrhetin acid esters 0.15%, oligofructose 1%, embodiment 3 institute
The Chinese medicine extract 4% prepared, Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUM ERYTHRORHIZON) extract 3%, shaggy-fruited dittany (DICTAMNUS
DESYCARPUS) root extract 0.1%, water surplus.
Embodiment 9
A kind of baby cream, including each component of following weight/mass percentage composition: Parleam 6%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) really fatty oil 3%, Flos Camelliae Japonicae (CAMELLIA JAPONICA) seed oil 2%, Fructus oleae europaeae (OLEA
EUROPAEA) fruit oil 1.5%, phytosterol 0.3%, tocopherol acetas 0.5%, glyceryl stearate 0.3%, cetearyl alcohol
1%, stearic acid 0.3%, polydimethylsiloxane 1.5%, pentaerythritol stearic acid ester 2 1.5%, glycerol 7%, butanediol 7%, sucrose
Many stearates 0.3%, polyvinylpyrrolidone 0.3%, stearyl alcohol glycyrrhetin acid esters 0.15%, oligofructose 1%, embodiment 3 institute
The Chinese medicine extract 4% prepared, Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUM ERYTHRORHIZON) extract 1.5%, shaggy-fruited dittany (DICTAMNUS
DESYCARPUS) root extract 1.5%, pantothenylol 0.1%, Aloe vulgaris (ALOE BARBADENSIS) leaf extract 3%, more than water
Amount.
Embodiment 10
A kind of baby cream, including each component of following weight/mass percentage composition: Parleam 6%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) really fatty oil 3%, Flos Camelliae Japonicae (CAMELLIA JAPONICA) seed oil 2%, Fructus oleae europaeae (OLEA
EUROPAEA) fruit oil 1.5%, phytosterol 0.3%, tocopherol acetas 0.5%, glyceryl stearate 0.3%, cetearyl alcohol
1%, stearic acid 0.3%, polydimethylsiloxane 1.5%, pentaerythritol stearic acid ester 2 1.5%, glycerol 7%, butanediol 7%, sucrose
Many stearates 0.3%, polyvinylpyrrolidone 0.3%, stearyl alcohol glycyrrhetin acid esters 0.15%, oligofructose 1%, embodiment 3 institute
The Chinese medicine extract 4% prepared, Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUM ERYTHRORHIZON) extract 1.5%, shaggy-fruited dittany (DICTAMNUS
DESYCARPUS) root extract 1.5%, pantothenylol 3%, Aloe vulgaris (ALOE BARBADENSIS) leaf extract 0.1%, more than water
Amount.
Comparative example 1
A kind of baby cream, including each component of following weight/mass percentage composition: Parleam 8%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) really fatty oil 1%, Flos Camelliae Japonicae (CAMELLIA JAPONICA) seed oil 3%, Fructus oleae europaeae (OLEA
EUROPAEA) fruit oil 1%, phytosterol 0.5%, tocopherol acetas 0.1%, glyceryl stearate 0.5%, cetearyl alcohol
0.5%, stearic acid 0.5%, polydimethylsiloxane 1%, pentaerythritol stearic acid ester 2 2%, glycerol 5%, butanediol 10%, sucrose is many
Stearate 0.1%, polyvinylpyrrolidone 0.5%, stearyl alcohol glycyrrhetin acid esters 0.1%, oligofructose 2%, water surplus.
Comparative example 2
A kind of baby cream, including each component of following weight/mass percentage composition: Parleam 8%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) really fatty oil 1%, Flos Camelliae Japonicae (CAMELLIA JAPONICA) seed oil 3%, Fructus oleae europaeae (OLEA
EUROPAEA) fruit oil 1%, phytosterol 0.5%, tocopherol acetas 0.1%, glyceryl stearate 0.5%, cetearyl alcohol
0.5%, stearic acid 0.5%, polydimethylsiloxane 1%, pentaerythritol stearic acid ester 2 2%, glycerol 5%, butanediol 10%, sucrose is many
Stearate 0.1%, polyvinylpyrrolidone 0.5%, stearyl alcohol glycyrrhetin acid esters 0.1%, the Chinese medicine extraction obtained by embodiment 2
Thing 4%, water surplus.
Comparative example 3
A kind of baby cream, including each component of following weight/mass percentage composition: Parleam 8%, Butyrospermum parkii
(BUTYROSPERMUM PARKII) really fatty oil 1%, Flos Camelliae Japonicae (CAMELLIA JAPONICA) seed oil 3%, Fructus oleae europaeae (OLEA
EUROPAEA) fruit oil 1%, phytosterol 0.5%, tocopherol acetas 0.1%, glyceryl stearate 0.5%, cetearyl alcohol
0.5%, stearic acid 0.5%, polydimethylsiloxane 1%, pentaerythritol stearic acid ester 2 2%, glycerol 5%, butanediol 10%, sucrose is many
Stearate 0.1%, polyvinylpyrrolidone 0.5%, stearyl alcohol glycyrrhetin acid esters 0.1%, water surplus.
Embodiment 11
The baby cream of embodiment 4-10 and comparative example 1-4 gained is carried out efficacy assessments, and wherein comparative example 4 is commercially available baby
Child's diaper ointment, concrete test is as follows:
Go eczema efficacy test method as follows: each experimental group all chooses 11 volunteers, in age 0-6 year, all there is eczema problem；
Using method: 2 weeks the most on probation, the most once, and mug；Contrasting the 0th day and the 2nd week photo, eczema symptom is complete
Being evaluated as of eliminating is effective, and what eczema symptom was eased is evaluated as effectively；What eczema symptom did not had a significant change is evaluated as nothing
Effect.Concrete test result such as table 1.
Table 1 removes eczema efficacy test log
| Effective | Effectively | Invalid | |
| Embodiment 4 | 4 | 6 | 1 |
| Embodiment 5 | 3 | 7 | 1 |
| Embodiment 6 | 4 | 7 | 0 |
| Embodiment 7 | 6 | 4 | 1 |
| Embodiment 8 | 7 | 4 | 0 |
| Embodiment 9 | 9 | 2 | 0 |
| Embodiment 10 | 10 | 1 | 0 |
| Comparative example 1 | 1 | 5 | 5 |
| Comparative example 2 | 1 | 6 | 4 |
| Comparative example 3 | 0 | 7 | 4 |
| Comparative example 4 | 1 | 7 | 3 |
Shown that by contrast experiment the result of table 1 is visible:
The contrast of embodiment 4-10 and comparative example 4 understands, and the baby cream obtained by the embodiment of the present invention has and preferably goes
Eczema effect；
The contrast of embodiment 4-6 and comparative example 1-3 understands, Herba Portulacae (PORTULACA OLERACEA) extract, oligofructose,
Yellow (REHMANINNIA CHINENSIS) root extract share to have and synergitic goes eczema effect；
Embodiment 7-8 understands with the contrast of embodiment 4-6, Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUM ERYTHRORHIZON) extract and shaggy-fruited dittany
(DICTAMNUS DESYCARPUS) root extract share, and can improve the skin care compositions of the treatment infant eczema of the present invention
Curative effect；
The contrast of embodiment 9-10 and embodiment 7-8 understands, and pantothenylol, leaf extract can for Aloe vulgaris (ALOE BARBADENSIS)
Promote the curative effect of the skin care compositions of the treatment infant eczema of the present invention further.
The above, be only presently preferred embodiments of the present invention, and the present invention not does any pro forma restriction, therefore
All contents without departing from technical solution of the present invention, any simply repair made for any of the above embodiments according to the technical spirit of the present invention
Change, equivalent variations and modification, all still fall within the range of technical solution of the present invention.
Claims (9)
1. the skin care compositions treating infant eczema, it is characterised in that include the component of following mass parts: Herba Portulacae
(PORTULACA OLERACEA) extract 0.1-3 part, oligofructose 0.1-2 part, Radix Rehmanniae (REHMANINNIA CHINENSIS)
Root extract 0.1-3 part.
The skin care compositions for the treatment of infant eczema the most according to claim 1, it is characterised in that described treatment baby children
The skin care compositions of youngster's eczema includes the component of following mass parts: Herba Portulacae (PORTULACA OLERACEA) extract 1.5 parts,
Oligofructose 1 part, Radix Rehmanniae (REHMANINNIA CHINENSIS) root extract 1.5 parts.
The skin care compositions for the treatment of infant eczema the most according to claim 1 and 2, it is characterised in that described treatment
The skin care compositions of infant eczema is possibly together with the component of following mass parts: Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUM ERYTHRORHIZON)
Extract 0.1-3 part, shaggy-fruited dittany (DICTAMNUS DESYCARPUS) root extract 0.1-3 part.
The skin care compositions for the treatment of infant eczema the most according to claim 3, it is characterised in that described treatment baby children
The skin care compositions of youngster's eczema is possibly together with the component of following mass parts: Radix Arnebiae (Radix Lithospermi) (LITHOSPERMUM ERYTHRORHIZON) is extracted
Thing 1.5 parts, shaggy-fruited dittany (DICTAMNUS DESYCARPUS) root extract 1.5 parts.
The skin care compositions for the treatment of infant eczema the most according to claim 1 and 2, it is characterised in that described treatment
The skin care compositions of infant eczema is possibly together with the component of following mass parts: pantothenylol 0.1-3 part, Aloe vulgaris (ALOE
BARBADENSIS) leaf extract 0.1-3 part.
6. the preparation method of the skin care compositions of the treatment infant eczema described in a claim 1 or 2, it is characterised in that
Comprise the following steps:
1) pulverize: by Herba Portulacae, Radix Rehmanniae mixing, dry, pulverize, sieve to obtain mixed-powder；
2) extraction: being immersed in ethanol solution by mixed-powder, microwave digestion obtains lixiviating solution；
3) filter: lixiviating solution is filtered, it is thus achieved that filtrate, then filtrate is evaporated, it is thus achieved that residue；
4) dissolve: by residue water dissolution, be subsequently adding normal hexane and extract, abandon normal hexane layer, it is thus achieved that aqueous phase, centrifugal reject
Precipitation, adds oligofructose, stirring and dissolving, i.e. obtains and remove eczema Chinese medicine extract.
The preparation method of the skin care compositions for the treatment of infant eczema the most according to claim 6, it is characterised in that include
Following steps:
1) pulverize: by Herba Portulacae, Radix Rehmanniae mixing, dry, pulverize, cross the screening of 50-100 eye mesh screen, prepare mixed-powder；
2) extraction: mixed-powder is immersed in (the mixed powder 6-7kg of 1kg in the ethanol solution that volume fraction is 71-75%
Ethanol solution), open frequency is microwave treatment 5-10 minute of 50KHZ, then stirring 1-2 hour, it is thus achieved that lixiviating solution；
3) filter: by lixiviating solution 400-500 mesh filter-cloth filtering, it is thus achieved that filtrate, then filtrate is evaporated, it is thus achieved that residue；
4) dissolve: by residue with water dissolution (water of the residue 20-30kg of 1kg), be subsequently adding normal hexane and carry out extracting (1kg
The normal hexane of residue 0.1-0.5kg), abandon normal hexane layer, it is thus achieved that aqueous phase, centrifugal reject precipitation, add oligofructose, stir
Mix dissolving, i.e. obtain and remove eczema Chinese medicine extract.
8. the skin care compositions of the treatment infant eczema described in any one of claim 1-5 application in skin care item.
9. a baby cream, it is characterised in that described baby cream comprises each of following weight/mass percentage composition
Component: Parleam 5-8%, Butyrospermum parkii (BUTYROSPERMUM PARKII) really fatty oil 1-5%, Flos Camelliae Japonicae (CAMELLIA
JAPONICA) seed oil 1-3%, Fructus oleae europaeae (OLEA EUROPAEA) fruit oil 1-2%, phytosterol 0.1-0.5%, tocopheryl acetate
Ester 0.1-1%, glyceryl stearate 0.1-0.5%, cetearyl alcohol 0.5-2%, stearic acid 0.1-0.5%, polydimethylsiloxane
1-2%, pentaerythritol stearic acid ester 2 1-2%, glycerol 5-10%, butanediol 5-10%, Sucrose Polystearic Acid Esters 0.1-0.5%, poly-second
Alkene pyrrolidone 0.1-0.5%, stearyl alcohol glycyrrhetin acid esters 0.1-0.2%, the treatment infant described in any one of claim 1-5
The skin care compositions 0.3-20% of eczema, water surplus.
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