CN106265243B - A kind of crissum wet tissue annex solution and its preparation method and application - Google Patents
A kind of crissum wet tissue annex solution and its preparation method and application Download PDFInfo
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- CN106265243B CN106265243B CN201610694529.7A CN201610694529A CN106265243B CN 106265243 B CN106265243 B CN 106265243B CN 201610694529 A CN201610694529 A CN 201610694529A CN 106265243 B CN106265243 B CN 106265243B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
- A47K10/00—Body-drying implements; Toilet paper; Holders therefor
- A47K10/16—Paper towels; Toilet paper; Holders therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
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Abstract
The present invention provides a kind of crissum wet tissue annex solutions and its preparation method and application, the raw material for preparing the annex solution includes compounding fabric extracting solution, anti-sensitizer, emollient, pH adjusting agent, preservative and water, wherein, the compounding fabric extracting solution is mixture one or more of in hazel extract, extract solution from aloe, rhodiola extract, Flos Lonicerae extractive solution, wild chrysanthemum extracting solution and borneol extracting solution.The compound botanical extracting solution of addition to skin play the role of convergence, it is anti-inflammatory, refrigerant, releive, assist antiallergic.In addition, crissum of the present invention is added to anti-sensitizer with wet tissue annex solution, facilitate the allergic reaction for alleviating skin, such as rubescent, the swollen symptoms such as rise, generate heat of skin.
Description
Technical field
The invention belongs to daily chemical product field, in particular to a kind of crissum wet tissue annex solution and preparation method thereof and answer
With.
Background technique
There are many current market sales of wet tissue type, and wet tissue is divided into human body wet tissue and object wet tissue two major classes.People
Body is divided into common wet tissue, wet sanitary napkins according to sanitary standard with wet tissue, according to purposes be divided into baby's wet tissue special, adult wet tissue,
Ms nurses wet tissue, impregnated wipe etc..The anus of people and surrounding be body discharges organ and the most used organ it
One, the people with various disease of anus keeps anus sanitation most important after an action of the bowels, if anus is not clean after an action of the bowels, patient
It can feel sick, or even cause cure the disease exacerbation or recurrence, so quick, safety, comfortable cleaning are needed, because human body crissum
Particularity needs the particularly customized a impregnated wipe for being specific to crissum.
Summary of the invention
The object of the present invention is to provide a kind of crissum wet tissue annex solutions and its preparation method and application.The crissum is with wet
The pH of towel annex solution is consistent with human body anal skin mucous membrane pH, and has convergence, anti-inflammatory, antiallergic, soothe the skin, promote blood vessel
The features such as contraction.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of crissum wet tissue annex solution, the raw material of crissum wet tissue annex solution include compounding fabric extracting solution, resist
Quick dose, emollient, pH adjusting agent, preservative and water, the weight fraction ratio of each raw material are as follows:
Compound botanical extracting solution 5-20
Anti-sensitizer 0.1-2
Emollient 2-5
PH adjusting agent 0.01-4
Preservative 0.02-1
Water 80-99.5.
Further, water used in is purified water.
Further, the compounding fabric extracting solution is hazel extract, extract solution from aloe, rhodiola extract, gold
One or more of mixture in honeysuckle flower extracting solution, wild chrysanthemum extracting solution and borneol extracting solution.
Further, the compounding fabric extracting solution is hazel extract, extract solution from aloe, rhodiola extract, gold
The mixture of honeysuckle flower extracting solution, wild chrysanthemum extracting solution and borneol extracting solution, the weight fraction ratio of each raw material are as follows:
Hazel extract 20
Extract solution from aloe 5
Rhodiola extract 5
Flos Lonicerae extractive solution 5
Wild chrysanthemum extracting solution 5
Borneol extracting solution 5.
Further, the anti-sensitizer be De Minshu, it is fragrant it is quick relax one or both of mixture.
Further, the pH adjusting agent is citric acid or sodium hydroxide.
Further, the emollient is the mixture of one or more of propylene glycol, glycerol, 1,3-BDO.
Further, the preservative is chlorhexidine gluconate, bi-imidazolidinyl urea, Bronopol, IPBC, oxybenzene first
The mixture of one or more of ester, Nipasol.
The preparation method of crissum wet tissue annex solution, which is characterized in that the preparation method comprises the following steps:
1) anti-sensitizer is dissolved in emollient by above-mentioned weight fraction ratio and obtains mixed liquor A；
2) it by above-mentioned weight fraction ratio will compound fabric extracting solution, preservative is added to the water, dissolves and stirs evenly
To mixed liquid B；
3) mixed liquor A is slowly added into mixed liquid B under stirring, is uniformly mixed, and adjusted with pH adjusting agent
PH 6 ~ 7 to get arrive crissum wet tissue annex solution.
It is another object of the present invention to what is be achieved through the following technical solutions:
A kind of crissum wet tissue, the crissum infiltrate base fabric with wet tissue annex solution by above-mentioned crissum with wet tissue and are made, adopt
It uses spunlace non-woven cloth as base fabric, is cut into predetermined size specification, sterilizing, disinfection；Water that is clipped, sterilizing, sterilized
In the prick nonwoven cloth infiltration natural ophthalmically acceptable wet tissue annex solution, infiltration amount is 200-400g/m2；It finally routinely folds, is close
After sealing aseptic packaging, that is, the crissum wet tissue is made.
Further, the base fabric is 100-200g/m2Spunlace non-woven cloth.
The present invention having the beneficial effect that compared with prior art
1, crissum of the present invention wet tissue annex solution is added to compound botanical extracting solution, compound botanical extracting solution pair
Skin play the role of convergence, it is anti-inflammatory, refrigerant, releive, assist antiallergic；
2, crissum of the present invention wet tissue annex solution, is added to anti-sensitizer, facilitates the allergic reaction for alleviating skin,
Such as rubescent, the swollen symptoms such as rise, generate heat of skin；
3, crissum wet tissue of the present invention, preferably 100-200g/m2Spunlace non-woven cloth is as base fabric, in screening process
Middle discovery is lower than 100g/m2Spunlace non-woven cloth easily makes hand be stained with dirt because nonwoven thickness is thin；Higher than 200g/m2Spun lacing without
Woven fabric increases anal skin excitement in use because non-woven fabrics sense of touch is solid.Therefore screening 100-200g/m2Spunlace non-woven cloth
As base fabric；
4, crissum of the present invention is personal nursing independent packaging product with wet tissue, and pH value, can be direct in neutral range
Contact perianal mucous membrane and skin, stingless excitation；
5, through on probation, crissum wet tissue of the present invention reaches the desired effect of product design requirement, by user
Favorable comment.
Specific embodiment
Embodiment 1
A kind of crissum wet tissue annex solution, the raw material of crissum wet tissue annex solution include compounding fabric extracting solution, resist
Quick dose, emollient, pH adjusting agent, preservative and water, the weight fraction ratio of each raw material are as follows:
Compound botanical extracting solution 5-20
Anti-sensitizer 0.1-2
Emollient 2-5
PH adjusting agent 0.01-4
Preservative 0.02-1
Purified water 80-99.5.
Further, the compounding fabric extracting solution is hazel extract, extract solution from aloe, rhodiola extract, gold
One or more of mixture in honeysuckle flower extracting solution, wild chrysanthemum extracting solution and borneol extracting solution.
Further, the anti-sensitizer be De Minshu, it is fragrant it is quick relax one or both of mixture.
Further, the pH adjusting agent is citric acid or sodium hydroxide.
Further, the emollient is the mixture of one or more of propylene glycol, glycerol, 1,3-BDO.
Further, the preservative is chlorhexidine gluconate, bi-imidazolidinyl urea, Bronopol, IPBC, oxybenzene first
The mixture of one or more of ester, Nipasol.
The preparation method of crissum wet tissue annex solution, which is characterized in that the preparation method comprises the following steps:
1) anti-sensitizer is dissolved in emollient by above-mentioned weight fraction ratio and obtains mixed liquor A；
2) it by above-mentioned weight fraction ratio will compound fabric extracting solution, preservative is added to the water, dissolves and stirs evenly
To mixed liquid B；
3) mixed liquor A is slowly added into mixed liquid B under stirring, is uniformly mixed, and adjusted with pH adjusting agent
PH 6 ~ 7 to get arrive crissum wet tissue annex solution.
A kind of crissum wet tissue, the crissum infiltrate base fabric with wet tissue annex solution by above-mentioned crissum with wet tissue and are made, adopt
It uses spunlace non-woven cloth as base fabric, is cut into predetermined size specification, sterilizing, disinfection；Water that is clipped, sterilizing, sterilized
In the prick nonwoven cloth infiltration natural ophthalmically acceptable wet tissue annex solution, infiltration amount is 200-400g/m2；It finally routinely folds, is close
After sealing aseptic packaging, that is, the crissum wet tissue is made.
Further, the base fabric is 100-200g/m2Spunlace non-woven cloth.
The quality standard of various extracting solutions is as follows:
Hazel extract:
Appearance colorless transparency liquid, pH(10% aqueous solution) 5.0-6.5, index of refraction (20 DEG C) 1.416-1.420, relatively
Density (20 DEG C) 1.0300-1.0360；
Extract solution from aloe:
Using aloe extract (10:1), appearance is configured in brown-green powder, loss on drying≤3%, ash content≤3%
5% aqueous solution；
Rhodiola extract:
Using gadol extract (3%), appearance is configured to 5% in brownish-yellow powder, loss on drying≤5%, ash content≤5%
Aqueous solution；
Flos Lonicerae extractive solution:
Using Honegsukle flower P.E, appearance is in brownish-yellow powder or chocolate brown powder, content: chlorogenic acid (C16 H18 O9) contain
Amount >=20%, loss on drying≤6% is configured to 2% aqueous solution；
Wild chrysanthemum extracting solution:
Appearance (25 DEG C) brown transparency liquid, total content >=2.5%, pH value 4.5-6.5；
Borneol extracting solution:
Appearance is in colourless transparent liquid, total content >=2%, pH value 4.5-6.5.
Unit of weight used is kilogram in the present embodiment, or gram；
Each raw material described in the present embodiment is the conventional products sold in the market.
Embodiment 2
The present embodiment is preferred embodiment on that basis of example 1, and raw materials used quality is same as Example 1, described
The weight fraction ratio of crissum each raw material of wet tissue annex solution are as follows:
Compound botanical extracting solution 8
Anti-sensitizer: De Minshu 1
Emollient: propylene glycol 3
PH adjusting agent: citric acid 0.25
Preservative: chlorhexidine gluconate 1, Bronopol 0.02, IPBC 0.01
Water 87.72；
Commercially available hazel extract, extract solution from aloe, rhodiola extract, Flos Lonicerae extractive solution, wild chrysanthemum are extracted
Liquid and borneol extracting solution according to 20 parts by weight of hazel extract, 5 parts by weight of extract solution from aloe, 5 parts by weight of rhodiola extract,
5 parts by weight of Flos Lonicerae extractive solution, 5 parts by weight of wild chrysanthemum extracting solution, 5 parts by weight of borneol extracting solution, obtain compound botanical extracting solution.
Embodiment 3
The present embodiment is preferred embodiment on that basis of example 1, and raw materials used quality is same as Example 1, described
The weight fraction ratio of crissum each raw material of wet tissue annex solution are as follows:
Compound botanical extracting solution 5
Anti-sensitizer: De Minshu 0.8 fragrant quick easypro 0.1
Emollient: 2 glycerol 2 of propylene glycol
PH adjusting agent: sodium hydroxide 0.03
Preservative: bi-imidazolidinyl urea 0.7, IPBC0.004, methyl hydroxybenzoate 0.16, Nipasol 0.015
Water 89.391；
The compounding fabric extracting solution is same as Example 2.
Embodiment 4
The present embodiment is preferred embodiment on that basis of example 1, and raw materials used quality is same as Example 1, described
The weight fraction ratio of crissum each raw material of wet tissue annex solution are as follows:
Compound botanical extracting solution 13
Anti-sensitizer: De Minshu 0.6 fragrant quick easypro 0.2
Emollient: propylene glycol 3,1,3-BDO 1
PH adjusting agent: citric acid 0.25
Preservative: chlorhexidine gluconate 1, Bronopol 0.02, IPBC 0.01
Water 80.92；
The compounding fabric extracting solution is same as Example 2.
Related test results:
By above-mentioned formula and by the different components of implementation method preparation, according to GB15979-2002 wet sanitary napkins microorganism
Index detects product, including total number of bacterial colonies, coliform, pathogenic pyogenic baeceria, fungus colony sum project.Respectively
Embodiment testing result entirely reaches: total number of bacterial colonies (cfu/mL)≤20, coliform is not detected, and pathogenic pyogenic baeceria is not
Detection, fungus colony sum are not detected.Meet prescribed requirement.
By above-mentioned formula and by the different components of implementation method preparation, product is carried out according to GB/T 27728-2011
Detection, including deviation, liquid content, package encapsulation, pH, transportable property fluorescent whitening agent project.Each embodiment testing result is complete
Portion reaches following standard: deviation >=-10%, liquid content >=1.7 times, package encapsulation meets the requirements, pH6.5-7.8, transportable property
Fluorescent whitening agent is not detected.Meet prescribed requirement.
Crissum wet tissue uses test:
It selects 400 volunteers to participate in free trial activity, is divided into four groups, every group of 100 people, respectively to the embodiment of the present invention
2,3,4 crissum wet tissue is tested, and the famous brand human body that another set has selected a occupation rate of market high makes pair of wet tissue
Than test.The test method of crissum wet tissue of the present invention: wiping crissum with crissum wet tissue after an action of the bowels, remembers to the evaluation result of using effect
Record is as follows:
Alleviate crissum stimulation to compare
As can be seen from the above table, consumer to use ophthalmically acceptable wet tissue of the invention to alleviating crissum stimulation situation, it is satisfied
Rate can achieve 90% or more, significant effect.
Claims (8)
1. a kind of crissum wet tissue annex solution, which is characterized in that the crissum is mentioned with the raw material of wet tissue annex solution by compound botanical
Take liquid, anti-sensitizer, emollient, pH adjusting agent, preservative and water composition, the weight fraction ratio of each raw material are as follows:
Compound botanical extracting solution 5-20
Anti-sensitizer 0.1-2
Emollient 2-5
PH adjusting agent 0.01-4
Preservative 0.02-1
Water 80-99.5；
The compound botanical extracting solution is hazel extract, extract solution from aloe, rhodiola extract, Flos Lonicerae extractive solution, open country
The mixture of chrysanthemum extract liquid and borneol extracting solution, the weight fraction ratio of each raw material are as follows:
Hazel extract 20
Extract solution from aloe 5
Rhodiola extract 5
Flos Lonicerae extractive solution 5
Wild chrysanthemum extracting solution 5
Borneol extracting solution 5；
The pH value of the crissum wet tissue annex solution is 6 ~ 7.
2. crissum according to claim 1 wet tissue annex solution, which is characterized in that the anti-sensitizer is De Minshu, fragrant quick
One or both of easypro mixture.
3. crissum according to claim 1 wet tissue annex solution, which is characterized in that the pH adjusting agent is citric acid or hydrogen
Sodium oxide molybdena.
4. crissum according to claim 1 wet tissue annex solution, which is characterized in that the emollient be propylene glycol, glycerol,
The mixture of one or more of 1,3-BDO.
5. crissum according to claim 1 wet tissue annex solution, which is characterized in that the preservative be gluconic acid chlorine oneself
The mixture of one or more of fixed, bi-imidazolidinyl urea, Bronopol, IPBC, methyl hydroxybenzoate, Nipasol.
6. a kind of preparation method of crissum as described in any one in claim 1-5 wet tissue annex solution, which is characterized in that described
Preparation method the following steps are included:
1) anti-sensitizer is dissolved in emollient by weight fraction ratio described in accordance with the claim 1 obtains mixed liquor A；
2) compound botanical extracting solution, preservative are added to the water by weight fraction ratio described in accordance with the claim 1, dissolve and stir
Uniformly obtain mixed liquid B；
3) mixed liquor A is slowly added into mixed liquid B under stirring, is uniformly mixed, and adjust pH 6 with pH adjusting agent
~ 7 to get arrive crissum wet tissue annex solution.
7. a kind of crissum wet tissue, which is characterized in that the crissum wet tissue is by crissum as described in any one in claim 1-5
It is made with wet tissue annex solution infiltration base fabric, using spunlace non-woven cloth as base fabric, is cut into predetermined size specification, sterilizing, disinfection；
Spunlace non-woven cloth that is clipped, sterilizing, the sterilized infiltration crissum in wet tissue annex solution, infiltration amount is 200-
400g/m2；It finally routinely folds, after sealed, sterile packaging, that is, the crissum wet tissue is made.
8. crissum wet tissue according to claim 7, which is characterized in that the base fabric is 100-200g/m2Spun lacing nonwoven
Cloth.
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| CN109833412A (en) * | 2019-03-15 | 2019-06-04 | 武汉马应龙大健康有限公司 | A kind of hemorrhoid wet tissue and preparation method thereof |
| CN115089648A (en) * | 2022-07-04 | 2022-09-23 | 马应龙大健康有限公司 | Sanitary wet tissue for preventing/treating haemorrhoids and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1673326A (en) * | 2005-04-20 | 2005-09-28 | 王浩贵 | Six-flower detergent |
| CN101953860A (en) * | 2010-04-19 | 2011-01-26 | 铜陵洁雅生物科技股份有限公司 | Wet tissue for relieving hemorrhoid symptom and production method thereof |
| CN105342864A (en) * | 2015-11-23 | 2016-02-24 | 上海银京医用卫生材料有限公司 | Cleaning wet wipe containing pharmaceutical grade witch hazel extract |
| CN105662961A (en) * | 2016-02-24 | 2016-06-15 | 浙江绿飞诗日用品有限公司 | Haemorrhoid wet tissue |
-
2016
- 2016-08-19 CN CN201610694529.7A patent/CN106265243B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1673326A (en) * | 2005-04-20 | 2005-09-28 | 王浩贵 | Six-flower detergent |
| CN101953860A (en) * | 2010-04-19 | 2011-01-26 | 铜陵洁雅生物科技股份有限公司 | Wet tissue for relieving hemorrhoid symptom and production method thereof |
| CN105342864A (en) * | 2015-11-23 | 2016-02-24 | 上海银京医用卫生材料有限公司 | Cleaning wet wipe containing pharmaceutical grade witch hazel extract |
| CN105662961A (en) * | 2016-02-24 | 2016-06-15 | 浙江绿飞诗日用品有限公司 | Haemorrhoid wet tissue |
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