CN106265243A - A kind of crissum wet tissue annex solution and its preparation method and application - Google Patents
A kind of crissum wet tissue annex solution and its preparation method and application Download PDFInfo
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- CN106265243A CN106265243A CN201610694529.7A CN201610694529A CN106265243A CN 106265243 A CN106265243 A CN 106265243A CN 201610694529 A CN201610694529 A CN 201610694529A CN 106265243 A CN106265243 A CN 106265243A
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- solution
- crissum
- extracting solution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47K—SANITARY EQUIPMENT NOT OTHERWISE PROVIDED FOR; TOILET ACCESSORIES
- A47K10/00—Body-drying implements; Toilet paper; Holders therefor
- A47K10/16—Paper towels; Toilet paper; Holders therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
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Abstract
The invention provides a kind of crissum wet tissue annex solution and its preparation method and application, the raw material preparing described annex solution includes compounding fabric extracting solution, anti-sensitizer, emollient, pH adjusting agent, preservative and water, wherein, described compounding fabric extracting solution is the mixture of one or more in Radix Hamamelidis Mollis extracting solution, Aloe extraction solution, Radix Rhodiolae extracting solution, Flos Lonicerae extractive solution, Flos Chrysanthemi Indici extracting solution and Borneolum Syntheticum extracting solution.The described compound botanical extracting solution added has convergence, antiinflammatory, refrigerant, the effect of antiallergic of releiving, assist to skin.It addition, crissum wet tissue annex solution of the present invention with the addition of anti-sensitizer, contribute to alleviating the anaphylaxis of skin, the symptom such as such as skin rubescent, swollen rises, heating.
Description
Technical field
The invention belongs to cosmetics of everyday use field, with wet tissue annex solution and preparation method thereof and answer particularly to a kind of crissum
With.
Background technology
The wet tissue kind sold in the market is a lot, and wet tissue is divided into human body wet tissue and the big class of object wet tissue two.People
Body wet tissue is divided into common wet tissue, wet sanitary napkins according to sanitary standard, according to purposes be divided into baby's wet tissue special, adult's wet tissue,
Ms nurses wet tissue, impregnated wipe etc..The anus of people and be around body discharges organ, be also the most used organ it
One, suffer from the people of various anus, keep anus sanitation most important after an action of the bowels, if anus does not cleans totally after an action of the bowels, patient
Can feel sick, even cause to cure the disease and increase the weight of or recur, so needing quick, safe, comfortable cleaning, because human body crissum
Particularity, needs the particularly customized a impregnated wipe being specific to crissum.
Summary of the invention
It is an object of the invention to provide a kind of crissum wet tissue annex solution and its preparation method and application.Described crissum is with wet
The pH of towel annex solution is consistent with human body anal skin mucosa pH, and has convergence, antiinflammatory, antiallergic, skin of releiving, promotes blood vessel
The features such as contraction.
It is an object of the invention to be achieved through the following technical solutions:
A kind of crissum wet tissue annex solution, the raw material of described crissum wet tissue annex solution include compounding fabric extracting solution, anti-sensitizer,
Emollient, pH adjusting agent, preservative and water, the ratio of weight and number of each raw material is:
Compound botanical extracting solution 5-20
Anti-sensitizer 0.1-2
Emollient 2-5
PH adjusting agent 0.01-4
Preservative 0.02-1
Water 80-99.5.
Further, water wherein used is purified water.
Further, described compounding fabric extracting solution is Radix Hamamelidis Mollis extracting solution, Aloe extraction solution, Radix Rhodiolae extracting solution, gold
The mixture of one or more in Flos Lonicerae extracting solution, Flos Chrysanthemi Indici extracting solution and Borneolum Syntheticum extracting solution.
Further, described compounding fabric extracting solution is Radix Hamamelidis Mollis extracting solution, Aloe extraction solution, Radix Rhodiolae extracting solution, gold
Flos Lonicerae extracting solution, Flos Chrysanthemi Indici extracting solution and the mixture of Borneolum Syntheticum extracting solution, the weight fraction ratio of each raw material is:
Radix Hamamelidis Mollis extracting solution 20
Aloe extraction solution 5
Radix Rhodiolae extracting solution 5
Flos Lonicerae extractive solution 5
Flos Chrysanthemi Indici extracting solution 5
Borneolum Syntheticum extracting solution 5.
Further, described anti-sensitizer be De Minshu, fragrant quick relax in one or both mixture.
Further, described pH adjusting agent is citric acid or sodium hydroxide.
Further, the mixture of one or more during described emollient is propylene glycol, glycerol, 1,3 butylene glycol.
Further, described preservative is chlorhexidine gluconate, double imidazolidinyl urea, Bronopol, IPBC, oxybenzene first
The mixture of one or more in ester, propyl hydroxybenzoate.
The preparation method of described crissum wet tissue annex solution, it is characterised in that described preparation method comprises the following steps:
1) by above-mentioned ratio of weight and number anti-sensitizer is dissolved in emollient and obtains mixed liquor A；
2) by above-mentioned ratio of weight and number, compounding fabric extracting solution, preservative are added to the water, dissolve and be uniformly mixing to obtain mixed
Close liquid B；
3) mixed liquor A is slowly added in mixed liquid B under stirring, mix homogeneously, and adjusts pH 6 by pH adjusting agent
~ 7, i.e. obtain described crissum wet tissue annex solution.
It is another object of the present invention to be achieved through the following technical solutions:
A kind of crissum wet tissue, described crissum wet tissue is prepared by above-mentioned crissum wet tissue annex solution infiltration base fabric, uses water
Prick nonwoven cloth, as base fabric, is cut into given size specification, sterilizing, sterilization；The most clipped, sterilizing, the spun lacing sterilized without
Spinning in the natural ocular wet tissue annex solution described in cloth infiltration, infiltration amount is 200-400g/m2；Finally fold routinely, seal nothing
After bacterium packaging, i.e. make described crissum wet tissue.
Further, described base fabric is 100-200g/m2Spun-laced nonwoven fabric.
The present invention having the beneficial effect that compared to existing technology
1, crissum wet tissue annex solution of the present invention, with the addition of compound botanical extracting solution, and compound botanical extracting solution is to skin
There are convergence, antiinflammatory, refrigerant, the effect of antiallergic of releiving, assist；
2, crissum wet tissue annex solution of the present invention, with the addition of anti-sensitizer, contributes to alleviating the anaphylaxis of skin, such as
The symptoms such as skin rubescent, swollen rises, heating；
3, crissum wet tissue of the present invention, preferably 100-200g/m2Spun-laced nonwoven fabric, as base fabric, is sent out in screening process
Now less than 100g/m2Spun-laced nonwoven fabric, because nonwoven thickness is thin, easily makes hand be stained with dirt；Higher than 200g/m2Spun-laced nonwoven fabric
Because non-woven fabrics sense of touch is solid, in using, anal skin excitement is increased.Therefore screening 100-200g/m2Spun-laced nonwoven fabric conduct
Base fabric；
4, crissum wet tissue of the present invention is personal nursing independent packaging product, and pH value, at neutral range, can directly contact
Perianal mucosa and skin, stingless excitation；
5, through on probation, crissum wet tissue of the present invention all reaches the Expected Results of product design requirement, by user's favorable comment.
Detailed description of the invention
Embodiment 1
A kind of crissum wet tissue annex solution, the raw material of described crissum wet tissue annex solution include compounding fabric extracting solution, anti-sensitizer,
Emollient, pH adjusting agent, preservative and water, the ratio of weight and number of each raw material is:
Compound botanical extracting solution 5-20
Anti-sensitizer 0.1-2
Emollient 2-5
PH adjusting agent 0.01-4
Preservative 0.02-1
Purified water 80-99.5.
Further, described compounding fabric extracting solution is Radix Hamamelidis Mollis extracting solution, Aloe extraction solution, Radix Rhodiolae extracting solution, gold
The mixture of one or more in Flos Lonicerae extracting solution, Flos Chrysanthemi Indici extracting solution and Borneolum Syntheticum extracting solution.
Further, described anti-sensitizer be De Minshu, fragrant quick relax in one or both mixture.
Further, described pH adjusting agent is citric acid or sodium hydroxide.
Further, the mixture of one or more during described emollient is propylene glycol, glycerol, 1,3 butylene glycol.
Further, described preservative is chlorhexidine gluconate, double imidazolidinyl urea, Bronopol, IPBC, oxybenzene first
The mixture of one or more in ester, propyl hydroxybenzoate.
The preparation method of described crissum wet tissue annex solution, it is characterised in that described preparation method comprises the following steps:
1) by above-mentioned ratio of weight and number anti-sensitizer is dissolved in emollient and obtains mixed liquor A；
2) by above-mentioned ratio of weight and number, compounding fabric extracting solution, preservative are added to the water, dissolve and be uniformly mixing to obtain mixed
Close liquid B；
3) mixed liquor A is slowly added in mixed liquid B under stirring, mix homogeneously, and adjusts pH 6 by pH adjusting agent
~ 7, i.e. obtain described crissum wet tissue annex solution.
A kind of crissum wet tissue, described crissum wet tissue is prepared by above-mentioned crissum wet tissue annex solution infiltration base fabric, adopts
With spun-laced nonwoven fabric as base fabric, it is cut into given size specification, sterilizing, sterilization；The most clipped, sterilizing, the water sterilized
Natural ocular described in prick nonwoven cloth infiltration is with in wet tissue annex solution, and infiltration amount is 200-400g/m2；Last fold the most routinely, close
After envelope aseptic packaging, i.e. make described crissum wet tissue.
Further, described base fabric is 100-200g/m2Spun-laced nonwoven fabric.
The quality standard of various extracting solution is as follows:
Radix Hamamelidis Mollis extracting solution:
Appearance colorless transparency liquid, pH(10% aqueous solution) 5.0-6.5, index of refraction (20 DEG C) 1.416-1.420, relative density
(20 DEG C) 1.0300-1.0360；
Aloe extraction solution:
Using Aloe extract (10:1), outward appearance is brown-green powder, loss on drying≤3%, and ash≤3% is configured to 5%
Aqueous solution；
Radix Rhodiolae extracting solution:
Using Radix Rhodiolae extract (3%), outward appearance is brownish-yellow powder, loss on drying≤5%, and ash≤5% is configured to the water of 5%
Solution；
Flos Lonicerae extractive solution:
Using Flos Lonicerae extract, outward appearance is brownish-yellow powder or chocolate brown powder, content: chlorogenic acid (C16 H18 O9) content >=
20%, loss on drying≤6%, it is configured to the aqueous solution of 2%；
Flos Chrysanthemi Indici extracting solution:
Outward appearance (25 DEG C) brown transparency liquid, total content >=2.5%, pH value 4.5-6.5；
Borneolum Syntheticum extracting solution:
Outward appearance is colourless transparent liquid, total content >=2%, pH value 4.5-6.5.
In the present embodiment, unit of weight used is kilogram, it is also possible to for gram；
Each raw material described in the present embodiment is on market the conventional products sold.
Embodiment 2
The present embodiment is the preferred version on the basis of embodiment 1, and raw materials used quality is same as in Example 1, described crissum
With the ratio of weight and number of each raw material of wet tissue annex solution it is:
Compound botanical extracting solution 8
Anti-sensitizer: De Minshu 1
Emollient: propylene glycol 3
PH adjusting agent: citric acid 0.25
Preservative: chlorhexidine gluconate 1, Bronopol 0.02, IPBC 0.01
Water 87.72；
By the Radix Hamamelidis Mollis extracting solution being purchased, Aloe extraction solution, Radix Rhodiolae extracting solution, Flos Lonicerae extractive solution, Flos Chrysanthemi Indici extracting solution and
Borneolum Syntheticum extracting solution is according to Radix Hamamelidis Mollis extracting solution 20 weight portion, Aloe extraction solution 5 weight portion, Radix Rhodiolae extracting solution 5 weight portion, gold silver
Flower extracting solution 5 weight portion, Flos Chrysanthemi Indici extracting solution 5 weight portion, Borneolum Syntheticum extracting solution 5 weight portion, obtain compound botanical extracting solution.
Embodiment 3
The present embodiment is the preferred version on the basis of embodiment 1, and raw materials used quality is same as in Example 1, described crissum
With the ratio of weight and number of each raw material of wet tissue annex solution it is:
Compound botanical extracting solution 5
Anti-sensitizer: De Minshu 0.8 fragrant quick easypro 0.1
Emollient: propylene glycol 2 glycerol 2
PH adjusting agent: sodium hydroxide 0.03
Preservative: double imidazolidinyl urea 0.7, IPBC0.004, methyl hydroxybenzoate 0.16, propyl hydroxybenzoate 0.015
Water 89.391；
Described compounding fabric extracting solution is same as in Example 2.
Embodiment 4
The present embodiment is the preferred version on the basis of embodiment 1, and raw materials used quality is same as in Example 1, described crissum
With the ratio of weight and number of each raw material of wet tissue annex solution it is:
Compound botanical extracting solution 13
Anti-sensitizer: De Minshu 0.6 fragrant quick easypro 0.2
Emollient: propylene glycol 3,1,3 butylene glycol 1
PH adjusting agent: citric acid 0.25
Preservative: chlorhexidine gluconate 1, Bronopol 0.02, IPBC 0.01
Water 80.92；
Described compounding fabric extracting solution is same as in Example 2.
Related test results:
By above-mentioned formula the different components prepared by implementation, according to GB15979-2002 wet sanitary napkins microbiological indicator
Product is detected, including total number of bacterial colonies, coliform, pathogenic pyogenic baeceria, fungus colony sum project.Each enforcement
Example testing result entirely reaches: total number of bacterial colonies (cfu/mL)≤20, and coliform does not detects, and pathogenic pyogenic baeceria is not examined
Going out, fungus colony sum does not detects.Meet regulation requirement.
By above-mentioned formula the different components prepared by implementation, according to GB/T 27728-2011, product is carried out
Detection, including deviation, liquid content, package encapsulation, pH, transportable property fluorescent whitening agent project.Each embodiment testing result is complete
Portion reaches following standard: deviation >=-10%, liquid content >=1.7 times, package encapsulation meets the requirements, pH6.5-7.8, transportable property
Fluorescent whitening agent does not detects.Meet regulation requirement.
Crissum wet tissue uses to be tested:
Select 400 volunteers to participate in free trial activity, be divided into four groups, often organize 100 people, respectively to the embodiment of the present invention 2,3,
The crissum wet tissue of 4 is tested, and the famous brand human body wet tissue that another set has selected a market share high does contrast and surveys
Examination.The method of testing of crissum wet tissue of the present invention: after an action of the bowels with crissum wet tissue wiping crissum, to the evaluation result record of using effect such as
Following table:
Alleviate crissum stimulation to compare
As can be seen from the above table, consumer to use the present invention ophthalmically acceptable wet tissue to alleviate crissum stimulate situation, satisfaction rate can
To reach more than 90%, effect is notable.
Claims (10)
1. a crissum wet tissue annex solution, it is characterised in that the raw material of described crissum wet tissue annex solution includes compounding fabric
Extracting solution, anti-sensitizer, emollient, pH adjusting agent, preservative and water, the ratio of weight and number of each raw material is:
Compound botanical extracting solution 5-20
Anti-sensitizer 0.1-2
Emollient 2-5
PH adjusting agent 0.01-4
Preservative 0.02-1
Water 80-99.5.
Crissum wet tissue annex solution the most according to claim 1, it is characterised in that described compounding fabric extracting solution is gold thread
One in prunus mume (sieb.) sieb.et zucc. extracting solution, Aloe extraction solution, Radix Rhodiolae extracting solution, Flos Lonicerae extractive solution, Flos Chrysanthemi Indici extracting solution and Borneolum Syntheticum extracting solution
Or several mixture.
Crissum wet tissue annex solution the most according to claim 2, it is characterised in that described compounding fabric extracting solution is gold thread
Prunus mume (sieb.) sieb.et zucc. extracting solution, Aloe extraction solution, Radix Rhodiolae extracting solution, Flos Lonicerae extractive solution, Flos Chrysanthemi Indici extracting solution and the mixing of Borneolum Syntheticum extracting solution
Thing, the weight fraction ratio of each raw material is:
Radix Hamamelidis Mollis extracting solution 20
Aloe extraction solution 5
Radix Rhodiolae extracting solution 5
Flos Lonicerae extractive solution 5
Flos Chrysanthemi Indici extracting solution 5
Borneolum Syntheticum extracting solution 5.
Crissum wet tissue annex solution the most according to claim 1, it is characterised in that described anti-sensitizer is De Minshu, fragrant quick
One or both mixture in Shuing.
Crissum wet tissue annex solution the most according to claim 1, it is characterised in that described pH adjusting agent is citric acid or hydrogen
Sodium oxide.
Crissum wet tissue annex solution the most according to claim 1, it is characterised in that described emollient be propylene glycol, glycerol,
The mixture of one or more in 1,3 butylene glycol.
Crissum wet tissue annex solution the most according to claim 1, it is characterised in that described preservative is that gluconic acid chlorine is own
Calmly, the mixture of one or more in double imidazolidinyl urea, Bronopol, IPBC, methyl hydroxybenzoate, propyl hydroxybenzoate.
8. the preparation method of wet tissue annex solution of the crissum as described in any one of claim 1-7, it is characterised in that described
Preparation method comprises the following steps:
1) according to the ratio of weight and number described in claim 1 anti-sensitizer is dissolved in emollient and obtains mixed liquor A；
2) according to the ratio of weight and number described in claim 1, compounding fabric extracting solution, preservative are added to the water, dissolve and stir
Uniformly obtain mixed liquid B；
3) mixed liquor A is slowly added in mixed liquid B under stirring, mix homogeneously, and adjusts pH 6 by pH adjusting agent
~ 7, i.e. obtain described crissum wet tissue annex solution.
9. a crissum wet tissue, it is characterised in that described crissum wet tissue is by the crissum as described in any one of claim 1-7
Prepare by wet tissue annex solution infiltration base fabric, use spun-laced nonwoven fabric as base fabric, be cut into given size specification, sterilizing, sterilization；
In the natural ocular wet tissue annex solution described in the most clipped, sterilizing, the spun-laced nonwoven fabric infiltration sterilized, infiltration amount is 200-
400g/m2；After last folding routinely, sealed, sterile packaging, i.e. make described crissum wet tissue.
Crissum wet tissue the most according to claim 9, it is characterised in that described base fabric is 100-200g/m2Spun lacing nonwoven
Cloth.
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| CN201610694529.7A CN106265243B (en) | 2016-08-19 | 2016-08-19 | A kind of crissum wet tissue annex solution and its preparation method and application |
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|---|---|---|---|
| CN201610694529.7A CN106265243B (en) | 2016-08-19 | 2016-08-19 | A kind of crissum wet tissue annex solution and its preparation method and application |
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| CN106265243B CN106265243B (en) | 2019-04-30 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109833412A (en) * | 2019-03-15 | 2019-06-04 | 武汉马应龙大健康有限公司 | A kind of hemorrhoid wet tissue and preparation method thereof |
| CN115089648A (en) * | 2022-07-04 | 2022-09-23 | 马应龙大健康有限公司 | Sanitary wet tissue for preventing/treating haemorrhoids and preparation method thereof |
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| CN1673326A (en) * | 2005-04-20 | 2005-09-28 | 王浩贵 | Six-flower detergent |
| CN101953860A (en) * | 2010-04-19 | 2011-01-26 | 铜陵洁雅生物科技股份有限公司 | Wet tissue for relieving hemorrhoid symptom and production method thereof |
| CN105342864A (en) * | 2015-11-23 | 2016-02-24 | 上海银京医用卫生材料有限公司 | Cleaning wet wipe containing pharmaceutical grade witch hazel extract |
| CN105662961A (en) * | 2016-02-24 | 2016-06-15 | 浙江绿飞诗日用品有限公司 | Haemorrhoid wet tissue |
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2016
- 2016-08-19 CN CN201610694529.7A patent/CN106265243B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1673326A (en) * | 2005-04-20 | 2005-09-28 | 王浩贵 | Six-flower detergent |
| CN101953860A (en) * | 2010-04-19 | 2011-01-26 | 铜陵洁雅生物科技股份有限公司 | Wet tissue for relieving hemorrhoid symptom and production method thereof |
| CN105342864A (en) * | 2015-11-23 | 2016-02-24 | 上海银京医用卫生材料有限公司 | Cleaning wet wipe containing pharmaceutical grade witch hazel extract |
| CN105662961A (en) * | 2016-02-24 | 2016-06-15 | 浙江绿飞诗日用品有限公司 | Haemorrhoid wet tissue |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109833412A (en) * | 2019-03-15 | 2019-06-04 | 武汉马应龙大健康有限公司 | A kind of hemorrhoid wet tissue and preparation method thereof |
| CN115089648A (en) * | 2022-07-04 | 2022-09-23 | 马应龙大健康有限公司 | Sanitary wet tissue for preventing/treating haemorrhoids and preparation method thereof |
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| CN106265243B (en) | 2019-04-30 |
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