CN106262132A - A kind of antioxidant composition and preparation method thereof - Google Patents
A kind of antioxidant composition and preparation method thereof Download PDFInfo
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- CN106262132A CN106262132A CN201610905037.8A CN201610905037A CN106262132A CN 106262132 A CN106262132 A CN 106262132A CN 201610905037 A CN201610905037 A CN 201610905037A CN 106262132 A CN106262132 A CN 106262132A
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Abstract
The invention discloses a kind of antioxidant composition, it is made up of the component of following weight proportion: black Fructus Lycii powder 1000～1500 parts, vitamin A 0.5 part～15 parts, citric acid 0.1 part～1 part, malic acid 0.1 part～1 part, vitamin C 0.1 part～10 parts, vitamin E 0.005 part～0.05 part, lutein ester 1 part～50 parts.The antioxidant activity of antioxidant composition of the present invention is high, can effectively alleviate asthenopia, have good health value, and application prospect is good.
Description
Technical field
The present invention relates to a kind of antioxidant composition and preparation method thereof.
Background technology
Black Fructus Lycii (Lycium ruthenicum Murr.), for the mature fruit of Solanaceae Lycium, for perennial
Shrub, is distributed in the areas such as China Qinghai, Gansu, the Inner Mongol, Ningxia, Xinjiang, Tibet and North Shaanxi loess plateau；Belong to allusion quotation
The desert saline plant of type.Containing anthocyanidin, total polyphenols, polysaccharide, aminoacid, vitamin, flavone, biology in lycium ruthenicum fruit
The composition such as alkali, mineral element, has significant kidney tonifying, profit liver, improving eyesight, stomach invigorating, supplementing the brain, antioxidation, slow down aging and stimulates the menstrual flow
Deng biological activity.
But, current black Fructus Lycii product antioxidant effect needs to improve further.
Summary of the invention
Object of the present invention is to provide a kind of new antioxidant composition being mainly composed of black Fructus Lycii powder.
Antioxidant composition of the present invention, it is made up of the component of following weight proportion: black Fructus Lycii powder 1000～1500 parts,
Vitamin A 0.5 part～15 parts, citric acid 0.1 part～1 part, malic acid 0.1 part～1 part, vitamin C 0.1 part～10 parts, dimension
Raw element E 0.005 part～0.05 part, lutein ester 1 part～50 parts.
Preferably, described antioxidant composition is made up of the component of following weight proportion: 1200 parts of black Fructus Lycii powder, and dimension is raw
Element A 15 parts, citric acid 0.1 part, malic acid 1 part, vitamin C 0.1 part, vitamin E 0.005 part, lutein ester 1 part.
Wherein, described black Fructus Lycii powder is prepared as follows and forms: take black Fructus Lycii fresh fruit, and colloid mill grinds, and adjusts
PH, centrifugal, obtain supernatant, ceramic membrane filter, concentrate, obtain concentrated solution, be dried,.
Present invention also offers a kind of method preparing aforementioned antioxidant composition, step is as follows:
(1) take black Fructus Lycii fresh fruit, carry out colloid mill grinding, adjust pH, centrifugal, obtain supernatant；
(2) ceramic membrane filter, concentrates, obtains concentrated solution；
(3) vitamin A, citric acid, malic acid, vitamin C, vitamin E, lutein ester are added, mixing, it is dried,.
In step (1), the rotating speed that colloid mill grinds is 2000r/min～20000r/min, and the time is 10～5min.
In step (1), adjust pH value to 2～5；Adjusting pH is to use appointing in food stage citric acid, acetic acid, hydrochloric acid, malic acid
Meaning 1～3 kind of regulation.
In step (1), described centrifugal rotating speed is 2000r/min～20000r/min, and the time is 10～5min.
In step (2), ceramic membrane filter uses aperture to be 0.01 μm～the ceramic membrane filter of 0.5 μm, temperature 15 DEG C～
40 DEG C, pressure 1MPa～3MPa, filter under conditions of flow velocity 0.1～10 ton hour.
In step (2), concentration is to concentrate under the conditions of temperature≤50 DEG C, and the concentration being concentrated into concentrated solution is 1～1.5g/
ml。
In step (3), each liter of concentrated solution adds vitamin A 0.5g～15g, citric acid 0.1g～1g, malic acid
0.1g～1g, vitamin C 0.1g～10g, vitamin E 0.005g～0.05g, lutein ester 1g～50g.
In step (3), described being dried is to be dried under the conditions of temperature≤50 DEG C.
Present invention also offers aforementioned antioxidant composition use in preparing antioxidative food, health product or medicine
On the way.
Wherein, described antioxidative food, health product or medicine are to alleviate asthenopic food, health product or medicine
Product.
Present invention also offers a kind of antioxidative food, health product or medicine, it is to be combined by aforesaid antioxidation
Thing, adds that on food, health product or medicine, acceptable adjuvant is prepared from.
The present invention adds vitamin A, citric acid, malic acid, vitamin C, vitamin E, phylloxanthin in black Fructus Lycii powder
Ester combines, and has antioxidative synergistic effects, adds the anti-oxidation function of product, it is possible to by the antioxidation value of product by Radix osteomelis schwerinais Chinese holly
The ORAC 300-600 μm ole TE/g of Qi dry fruit, increases to 8000～8500 μm ole TE/g, and compositions alleviation regards
Tired effect is better than the lutein ester under same dosage, vitamin A effect, it is possible to be applied to Medicines and Health Product field.
The antioxidant activity of antioxidant composition of the present invention is high, can effectively alleviate asthenopia, have good health care valency
Value, application prospect is good.
Below by detailed description of the invention, the present invention is described in further details, but is not the limit to the present invention
System, according to the foregoing of the present invention, according to ordinary technical knowledge and the customary means of this area, above-mentioned without departing from the present invention
Under basic fundamental thought premise, it is also possible to make the amendment of other various ways, replace or change.
Detailed description of the invention
Colloid mill equipment HYA240/2.4.6 Qidong City Hua Yu Machinery Manufacturing Co., Ltd.
Ceramic membrane separation device Hefei Shi Jiemo Engineering Co., Ltd
Embodiment 1: a kind of antioxidant composition and preparation method thereof
1, preparation method
(1) taking black Fructus Lycii fresh fruit, (rotating speed that colloid mill grinds is 2000r/min, and the time is to carry out colloid mill grinding
10min), adjusting pH to be 2 with citric acid, obtain colloid mill lapping liquid, centrifugal (centrifugal rotating speed is 2000r/min, and the time is
10min), supernatant is obtained；
(2) (ceramic membrane filter uses aperture to be the ceramic membrane filter of 0.01 μm to ceramic membrane filter, and flow velocity is 0.1 ton/little
Time, temperature be 40 DEG C, pressure is 1MPa), concentrate (under the conditions of temperature≤50 DEG C concentrate, the concentration being concentrated into concentrated solution is 1.5g/
Ml), concentrated solution is obtained；
(3) each liter of concentrated solution adds vitamin A 0.5g, citric acid 1g, malic acid 0.1g, vitamin C 10g, dimension
Raw element E 0.005g, lutein ester 50g, mixing, it is dried under the conditions of temperature≤50 DEG C, obtains aubergine powder-product.
2, antioxidation value detection
Detection method:
Peroxide radical (ROO-) is the analog of Both peroxyl radical (HOO-), is by the hydrogen atom in HOO-
Substituted by organic group and obtain.ROO-is typically generation in the oxidizing process of protein and lipid.Additionally, with
In the inflammatory reaction that oxidative stress is relevant, neutrophil cell also can produce ROO-after being activated.ROO-can destroy cell membrane
With the structure of protein, therefore it is many virulence factors inactivating relevant various diseases to lipid autooxidation and enzyme.At present, have
Research shows, ROO-has the biggest relation with the vascularization in Tumor Growth.
With reference to Huang D.J., Ou B., Hampsch-Woodill.M., Flanagan.J.A., and
Prior.R.high-throughput assay of oxygen radical absorbance capacity(ORAC)
using a multichannel liquid handing system coupled with a microplate
fluorescence reader in 96-well format.Journal of agricultural and food
The detection method of chemistry.2002,50:4437-4444, the method is to destroy fluorescent probe according to ROO-, makes fluorescence intensity
Produce the principle of change, the anti-ROO-ability of testing sample is detected.Using AAPH as the source of generation ROO-, fluorescein
For fluorescent probe, vitamin E water-soluble analogues Trolox is standard reference material, carries out In Vitro Anti ROO-ability and measures." time
M-fluorescence signal figure " in area under curve (AUC) the biggest, represent the anti-ROO-of testing sample ability the strongest.The method is suitable for
The activity rating of the antiperoxide free radical of the water-soluble substances in plant extract, food, cosmetics, medicine etc..
Testing result:
Result shows, the antioxidation value of black fruit matrimony vine oxidation resistant compositions of the present invention is 8000 μm ole TE/g.
3, organoleptic indicator
Black fruit matrimony vine oxidation resistant compositions of the present invention is aubergine, and taste is sour-sweet.
The inventive method has prepared a kind of antioxidant composition, and its antioxidant activity is excellent, and has good
Mouthfeel, color and luster, fragrance, and formed by the Combined food such as black Fructus Lycii, citric acid, avirulence, antioxidative food can be made
Product or health product.
Embodiment 2: a kind of antioxidant composition and preparation method thereof
1, preparation method
(1) taking black Fructus Lycii fresh fruit, (rotating speed that colloid mill grinds is 20000r/min, and the time is to carry out colloid mill grinding
5min), adjust pH to be 5 with acetic acid, obtain colloid mill lapping liquid, centrifugal (centrifugal rotating speed is 20000r/min, and the time is 5min),
Supernatant；
(2) ceramic membrane filter (ceramic membrane filter uses aperture to be the ceramic membrane filter of 0.5 μm, flow velocity be 10 ton hour,
Temperature is 15 DEG C, and pressure is 1.2MPa), (concentrating under the conditions of temperature≤50 DEG C, the concentration being concentrated into concentrated solution is 1.2g/ in concentration
ml.), obtain concentrated solution；
(3) each liter of concentrated solution adds vitamin A 15g, citric acid 0.1g, malic acid 1g, vitamin C 0.1g, dimension
Raw element E 0.005g, lutein ester 1g, mixing, it is dried under the conditions of temperature≤50 DEG C, obtains aubergine powder-product.
2, antioxidation value detection
Detection method is with embodiment 1.
Testing result: the antioxidation value of black Fructus Lycii juice of the present invention is 8500 μm ole TE/g.
3, organoleptic indicator
Black fruit matrimony vine oxidation resistant compositions of the present invention is aubergine, and taste is sour-sweet.
The inventive method has prepared a kind of antioxidant composition, and its antioxidant activity is excellent, and has good
Mouthfeel, color and luster, fragrance, and formed by the Combined food such as black Fructus Lycii, citric acid, avirulence, antioxidative food can be made
Product or health product.
Embodiment 3: a kind of antioxidant composition and preparation method thereof
1, preparation method
(1) taking black Fructus Lycii fresh fruit, (rotating speed that colloid mill grinds is 10000r/min, and the time is to carry out colloid mill grinding
5min), adjust pH to be 4 with malic acid, obtain colloid mill lapping liquid, centrifugal (centrifugal rotating speed is 10000r/min, and the time is 5min),
Obtain supernatant；
(2) (ceramic membrane filter that ceramic membrane filter uses aperture to be 0.2 μm, flow velocity is 1 ton hour, temperature to ceramic membrane filter
Degree is 30 DEG C, and pressure is 3MPa), (concentrating under the conditions of temperature≤50 DEG C, the concentration being concentrated into concentrated solution is 1.0g/ml in concentration.),
Obtain concentrated solution；
(3) in each liter of concentrated solution add vitamin A 10g, citric acid 0.5g, malic acid 0.5g, vitamin C 0.5g,
Vitamin E 0.01g, lutein ester 5g, mixing, it is dried under the conditions of temperature≤50 DEG C, obtains aubergine powder-product.
2, antioxidation value detection
Detection method: with embodiment 1.
Testing result: the antioxidation value of black Fructus Lycii juice of the present invention is 8300 μm ole TE/g.
3, organoleptic indicator
Black fruit matrimony vine oxidation resistant compositions of the present invention is aubergine, and taste is sour-sweet.
The inventive method has prepared a kind of antioxidant composition, and its antioxidant activity is excellent, and has good
Mouthfeel, color and luster, fragrance, and formed by the Combined food such as black Fructus Lycii, citric acid, avirulence, antioxidative food can be made
Product or health product.
Embodiment 4 food of the present invention, health product or medicine
The antioxidant composition that Example 1～3 any one method prepares, adds food, health product or medicine
Acceptable adjuvant on product, mixing,.
Beneficial effects of the present invention is illustrated below by way of test example.
Test example 1 antioxidant composition of the present invention alleviates asthenopic effect
1, experimental technique
Participating in and selecting the age in the personnel of test is 19～35 years old, and for a long time with eye, vision fatiguability person is experimenter.Tested
This product, with reference to " health food inspection and assessment technique specification " (version in 2003), has been carried out scheduling to last 35d's by person's exclusion standard
The effect assessment of human feeding trial.
Experimental group eats the antioxidant composition of the embodiment of the present invention 1 preparation, every day 1 time, each 1g.Matched group is not for take
Using any medicine, every day 1 time, each 1g, lutein ester group eats lutein ester, every day 1 time, each 1g；Vitamin A group eats
Vitamin A, every day 1 time, each 1g.
2, experimental result
Result such as following table:
Result shows, antioxidant composition of the present invention can be obviously improved ophthalmic bloated, eye is puckery, eye aches, blurred vision, and
Effect is better than under same dose being used alone lutein ester or vitamin A.
Experimental result illustrates, antioxidant composition of the present invention can effectively alleviate asthenopia, excellent effect, and preparation technology
Simply, effect is substantially better than lutein ester or vitamin A, and cost is significantly lower than lutein ester and the Wei Sheng of Isodose simultaneously
Element A.
To sum up, antioxidant composition antioxidant activity of the present invention is high, and mouthfeel is good, it is possible to be used for alleviating asthenopia, has good
Good health value, application prospect is good.
Claims (10)
1. an antioxidant composition, it is characterised in that: it is made up of the component of following weight proportion: black Fructus Lycii powder 1000～
1500 parts, vitamin A 0.5 part～15 parts, citric acid 0.1 part～1 part, malic acid 0.1 part～1 part, vitamin C 0.1 part～
10 parts, vitamin E 0.005 part～0.05 part, lutein ester 1 part～50 parts.
Antioxidant composition the most according to claim 1, it is characterised in that: it is made up of the component of following weight proportion:
1200 parts of black Fructus Lycii powder, vitamin A 15 parts, citric acid 0.1 part, malic acid 1 part, vitamin C 0.1 part, vitamin E
0.005 part, lutein ester 1 part.
Antioxidant composition the most according to claim 1 and 2, it is characterised in that: described black Fructus Lycii powder is according to such as lower section
Method is prepared from: take black Fructus Lycii fresh fruit, and colloid mill grinds, and adjusts pH, centrifugal, obtains supernatant, ceramic membrane filter, concentrates, obtain dense
Contracting liquid, is dried,.
4. prepare the method for antioxidant composition described in claims 1 to 3 any one for one kind, it is characterised in that: step is as follows:
(1) take black Fructus Lycii fresh fruit, carry out colloid mill grinding, adjust pH, centrifugal, obtain supernatant；
(2) ceramic membrane filter, concentrates, obtains concentrated solution；
(3) vitamin A, citric acid, malic acid, vitamin C, vitamin E, lutein ester are added, mixing, it is dried,.
Preparation method the most according to claim 4, it is characterised in that: in step (1), the rotating speed that colloid mill grinds is
2000r/min～20000r/min, the time is 10～5min；
And/or, in step (1), adjust pH value to 2～5；Adjusting pH is to use in food stage citric acid, acetic acid, hydrochloric acid, malic acid
Any 1～3 kind of regulation；
And/or, in step (1), described centrifugal rotating speed is 2000r/min～20000r/min, and the time is 10～5min.
Preparation method the most according to claim 4, it is characterised in that: in step (2), ceramic membrane filter employing aperture is
0.01 μm～the ceramic membrane filter of 0.5 μm, in temperature 15 DEG C～40 DEG C, pressure 1MPa～3MPa, flow velocity 0.1～10 ton hour
Under conditions of filter；
And/or, in step (2), concentration is to concentrate under the conditions of temperature≤50 DEG C, and the concentration being concentrated into concentrated solution is 1～1.5g/
ml。
Preparation method the most according to claim 4, it is characterised in that: in step (3), each liter of concentrated solution adds dimension raw
Element A 0.5g～15g, citric acid 0.1g～1g, malic acid 0.1g～1g, vitamin C 0.1g～10g, vitamin E 0.005g
～0.05g, lutein ester 1g～50g；
And/or, in step (3), described being dried is to be dried under the conditions of temperature≤50 DEG C.
8. the antioxidant composition described in claims 1 to 3 any one is preparing antioxidative food, health product or medicine
In purposes.
Purposes the most according to claim 8, it is characterised in that: described antioxidative food, health product or medicine are slow
Solve asthenopic food, health product or medicine.
10. an antioxidative food, health product or medicine, it is characterised in that: it is by claims 1 to 3 any one
Described antioxidant composition, adds that on food, health product or medicine, acceptable adjuvant is prepared from.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2016108887686 | 2016-10-12 | ||
| CN201610888768 | 2016-10-12 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115500509A (en) * | 2022-09-01 | 2022-12-23 | 澳美制药(苏州)有限公司 | Eye-protecting edible composition and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991709A (en) * | 2010-11-09 | 2011-03-30 | 中国科学院西北高原生物研究所 | Method for preparing antioxidant lycium ruthenicum extract |
| CN103431404A (en) * | 2013-06-27 | 2013-12-11 | 苟春虎 | Vision protection and eyesight improving capsules |
-
2016
- 2016-10-18 CN CN201610905037.8A patent/CN106262132A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991709A (en) * | 2010-11-09 | 2011-03-30 | 中国科学院西北高原生物研究所 | Method for preparing antioxidant lycium ruthenicum extract |
| CN103431404A (en) * | 2013-06-27 | 2013-12-11 | 苟春虎 | Vision protection and eyesight improving capsules |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115500509A (en) * | 2022-09-01 | 2022-12-23 | 澳美制药(苏州)有限公司 | Eye-protecting edible composition and preparation method thereof |
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Application publication date: 20170104 |