CN1062478C - Medical extract for treating constipation - Google Patents

Medical extract for treating constipation Download PDF

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CN1062478C
CN1062478C CN98102653A CN98102653A CN1062478C CN 1062478 C CN1062478 C CN 1062478C CN 98102653 A CN98102653 A CN 98102653A CN 98102653 A CN98102653 A CN 98102653A CN 1062478 C CN1062478 C CN 1062478C
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parts
radix
semen
constipation
treating constipation
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CN1240652A (en
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邓景风
邓锦煌
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Abstract

The present invention relates to ointment for treating constipation, which is prepared from semen pruni, senna leaf, areca seed, black sesame, prepared rhizome of rehmannia, rehmannia dride rhizome, figwort root, angelica, tuckahoe, licorice root, honey and beeswax. Water is added to raw materials, liquid is decocted, and thus, ointment with the relative density of 1.30 to 1.40 is prepared through filtration and concentration. 12.15 g of crude medicines are contained in each 9 g of ointment. By observing the clinical curative effects of 100 cases, the present invention has the effects on nourishing Yin, moistening dryness and relaxing the bowel. The total effective rate is 91%, and the obvious effective rate is 58%.

Description

Medical extract for treating constipation
The present invention relates to a kind of medical extract for treating constipation, this relieving constipation cream is processed by plurality of Chinese.
Constipation is a common clinical symptoms, can cause by multiple reason, wherein see at most, the treatment of Chinese medicine with functional constipation, the normal cathartic that adopts, cathartic has the admittance stool, and it is stagnant to get rid of the intestines and stomach, cleanses excess-heat, attack by effects such as hydrops in the body, mainly be applicable to interior-excess syndrome, because the state of an illness difference of interior-excess syndrome, therefore be divided into purgation with drugs of cold nature, relaxing the bowels with purgatives of warm nature, relaxing the bowels with lubricant drugs, drastic purgation is relieved oedema or abdominal distension through diuresis or purgation and five kinds of reinforcement and elimination in combination.Relaxing the bowels with lubricant drugs method wherein has the laxation of moisturizing defecation, is applicable to the intestine-dryness due to consumption of fluid constipation, or constipation due to old, puerperal blood deficiency.Relaxing the bowels with lubricant drugs method patent medicine commonly used has Fructus Cannabis Bolus, wuren pills and pill for smoothing intestines.Fructus Cannabis Bolus is by Fructus Cannabis, Semen Armeniacae Amarum, Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus, Radix Paeoniae Alba prescription, making pellets by mixing medical powder with honey, function: intestine moistening purging heat to relax the bowels,<Treatise on Febrile Diseases 〉.Wuren pills cures mainly intestine-dryness due to consumption of fluid by Semen Persicae, Semen Armeniacae Amarum, Semen Pruni, Semen Platycladi, Semen pini koraiensis and Pericarpium Citri Reticulatae prescription, and it is unfavorable to defecate,<Shi Yi De Xiao Fang, Effective Formulae Handed Down for Generations 〉.Pill for smoothing intestines is by Radix Et Rhizoma Rhei, Radix Angelicae Sinensis, Rhizoma Et Radix Notopterygii, Semen Persicae and Fructus Cannabis prescription, and making pellets by mixing medical powder with honey cures mainly constipation, anorexia,<stomach spleen opinion 〉.Adopt cathartic drugs such as Radix Et Rhizoma Rhei more in the above-mentioned Chinese medicine, thereby following deficiency is arranged, the one, zest is arranged, the 2nd, side effect is big, and the 3rd, more serious constipation can appear after the drug withdrawal.
The object of the present invention is to provide a kind of medical extract for treating constipation, this relieving constipation cream improves intestinal peristalsis promoting by nourshing Yin and drynsessmoistening prescription, reconciles the body fluid balance, can fundamentally eliminate constipation.
The object of the present invention is achieved like this: a kind of medical extract for treating constipation, and it is the unguentum of being made by the following weight Chinese medicinal raw materials,
Semen Pruni 20-30 part Folium Sennae 20-30 part Semen Arecae 15-20 part
Semen Sesami Nigrum 20-30 part Radix Rehmanniae Preparata 15-20 part Radix Rehmanniae 20-30 part
Radix Scrophulariae 20-25 part Radix Angelicae Sinensis 15-20 part Poria 20-25 part
Radix Glycyrrhizae 10-15 part Mel 20-25 part Cera Flava 20-25 part.Above-mentioned raw materials is by adding decocting liquid, filtration, concentrating and make the mastic that relative density is 1.30-1.40.
Semen Pruni, Folium Sennae among the present invention are combined into monarch drug, the relieving constipation of intestine moistening cathartic; Semen Arecae, Semen Sesami Nigrum, Radix Rehmanniae Preparata, the Radix Rehmanniae, Radix Scrophulariae are ministerial drug altogether, and a large amount of YIN nourishing increase liquid, and the not only capable efficacy of a drug of principal drug assistance and healthy energy, and YIN nourishing liquid with purging heat to relax the bowels, have the effect of softening mass and moistening dryness eliminating stagnation simultaneously; Radix Angelicae Sinensis, Poria are strengthened invigorating qi and benefiting blood, and strengthening the spleen and stomach with the power of YIN nourishing loosening bowel to relieve constipation, is adjuvant drug; But Radix Glycyrrhizae, Mel, Cera Flava coordinating the actions of various ingredients in a prescription are moisturized laxation, are messenger drug altogether; All medicines share, and make just to be so incensed that fortune, and cloudy liquid must be answered, and the efficacy of a drug must be drawn, and stool can be led to, the pathogenic heat self-balancing.
The present invention cure mainly because of the gastrointestinal deficiency of YIN scorching, the constipation that deficiency of body fluid causes, the functional constipation that belongs to deficiency of YIN intestinal dryness type for differential diagnosis in tcm, can play the effect of " supplementing fluid to relax the bowels ", the present invention is through Beijing institute of traditional Chinese medicine, Dongzhimen Hospital, Beijing Univ of Traditional Chinese Medicine, 100 routine clinical observation on the therapeutic effect of Xuan Wu, Beijing institute of traditional Chinese medicine confirm, truly have YIN nourishing, moisturize, the effect of relieving constipation, total effective rate is 91%, obvious effective rate 58%.
Drug usage: obey 9 grams at every turn, obey every day 2 times, warm boiled water, per 2 weeks are a course of treatment.Clinical observation on the therapeutic effect the results are shown in Table 1, table 2.
Integration relatively before and after this group of table 1 patient constipation and the treatment of whole body situation
Integral mean value before treating Treat the back integral mean value Mean value standard error before and after the treatment T value p value
Total mark 9.83 2.73 7.66±0.36 21.28 <0.001
Infrequent defecation 1.95 0.36 1.59±0.15 10.60 <0.001
Just matter 2.15 0.43 1.72±0.12 14.33 <0.001
Constipation difficulty situation 1.99 0.47 1.52±0.11 13.82 <0.001
Each defecation time 2.11 0.64 1.47±0.12 12.25 <0.001
Dry mouth and throat 0.72 0.53 0.19±0.04 4.75 <0.001
Fidgety in the heart 0.31 0.07 0.24±0.03 8.00 <0.001
Abdominal distention 0.38 0.07 0.31±0.05 6.20 <0.001
Dizzy 0.26 0.08 0.18±0.14 1.29 >0.05
Cardiopalmus 0.16 0.04 0.12±0.05 2.40 <0.05
The clinical card marquis of this group of table 2 constipation patient curative effect
Add up to Produce effects Effectively Invalid Effective percentage %
Example number % 100 100 58 58 33 33 9 9 91 91
The present invention starts with from the cause of constipation, by nourshing Yin and drynsessmoistening prescription, reach and improve intestinal peristalsis promoting, in human body, form circulation smoothly and drain, get rid of toxin and refuse behind the metabolism rapidly, regulate human body body fluid balance, fundamentally eliminate constipation, therefore, the present invention has tonification and warm-dryness syndrome not, rushes down not hinder positive distinguishing feature down.
The invention will be further described below in conjunction with embodiment
Embodiment one: the weight proportion by raw material of Chinese medicine is got it filled,
Semen Pruni 20 gram Folium Sennae 20 gram Semen Arecaes 15 grams
The Semen Sesami Nigrum 20 gram Radix Rehmanniaes Preparata 15 gram Radix Rehmanniae 20 grams
Radix Scrophulariae 20 gram Radix Angelicae Sinensis 15 gram Poria 20 grams
Radix Glycyrrhizae 10 gram Mel 20 gram Cera Flavas 20 grams are earlier with Semen Pruni, Folium Sennae, Semen Arecae, Semen Sesami Nigrum, Radix Rehmanniae Preparata, the Radix Rehmanniae, Radix Scrophulariae, Radix Angelicae Sinensis, Poria, Radix Glycyrrhizae decocts with water twice, the water that adds for the first time 10 times of suitable doses, decocted 3 hours, the water that adds for the second time 8 times of suitable doses, decocted 2 hours, merge twice decoction liquor, filter, filtrate concentrates, and makes clear paste, when this clear paste is 50 ℃ in temperature, its relative density is 1.10, with Mel, Cera Flava heating refining back adds mixing in the clear paste, is condensed into mastic, when this mastic is 50 ℃ in temperature, its relative density is 1.30-1.40, with this mastic pack, every bag 9 gram contains crude drug amount 12.15 grams in per 9 gram mastic.
Embodiment two: the ratio of weight and number by raw material of Chinese medicine is got it filled,
Semen Pruni 30 gram Folium Sennae 30 gram Semen Arecaes 20 grams
Who ground of the Semen Sesami Nigrum 30 grams 20 gram Radix Rehmanniae, 30 grams
Radix Scrophulariae 25 gram Radix Angelicae Sinensis 20 gram Poria 25 grams
Radix Glycyrrhizae 15 gram Mel 25 gram Cera Flavas 25 grams are earlier with Semen Pruni, Folium Sennae, Semen Arecae, Semen Sesami Nigrum, Radix Rehmanniae Preparata, the Radix Rehmanniae, Radix Scrophulariae, Radix Angelicae Sinensis, Poria, Radix Glycyrrhizae decocts with water twice, the water that adds for the first time 10 times of suitable doses, decocted 3 hours, the water that adds for the second time 8 times of suitable doses, decocted 2 hours, and merged twice decoction liquor, filter, filtrate concentrates, make clear paste, when this clear paste was 50 ℃ in temperature, its relative density was 1.10, with Mel, Cera Flava heating refining back adds mixing in the clear paste, be condensed into mastic, when this mastic was 50 ℃ in temperature, its relative density was 1.30-1.40, with this mastic pack, every bag 9 gram.
Model case one:
Song * *: woman, 68 years old, medical record number 58079, consultation time nineteen ninety-five JIUYUE 11 days
Year surplus patient's difficult defecation 10, the 6-7 day delegation of defecating usually, dry and hard balling-up, exert during defecation and can not earn any more, each defecation time is half an hour approximately, accompanies weak, dry mouth and throat, dizziness, cardiopalmus, stool changes yellow loose stool again after taking TONGBIAN LING or Folium Sennae tea, and 5-6 days delegation have a medical check-up, blood pressure Bp22/11Kpa, refreshing clear, spirit can, two lungs (one), heart rate 80 times, rule is neat, noise (one), abdomen is soft, two knee joint edema () down.Internal rectum and swollen thing, the few Tianjin of red tongue with thin and yellow fur, thready pulse without strength.Blood, urine, just conventional normal, electrocardiogram, the hepatic and renal function inspection is normal.Clinical diagnosis: constipation.Differential diagnosis in tcm: deficiency of YIN dryness of the intestine.
It is oral that medical extract for treating constipation is used in treatment, each 9 grams, every day 2 times, stool transfers delegation on the 2nd to after three days, and the difficult defecation situation is clearly better, and treats after 14 days, stool is yellow soft stool once a day, and defecation is unobstructed, nothing is had blood in stool, weak, dry mouth and throat disappears white and thin fur, light red tongue, stringy and rolling pulse, physico-chemical examination are all normal.
Model case two:
Liu * *: man, 50 years old, consultation time nineteen ninety-five JIUYUE 25 days
Year surplus patient's difficult defecation 10, the delegation next day of the stool usually, big dry stool is how soft few, about 15 minutes of each defecation time, and defecation sense is not to the utmost arranged, companion's dry mouth and throat, the abdominal distention whole body situation of having a medical check-up is good, 36 ℃ of body temperature, blood pressure Bp19/11Kpa, heart rate 84 times, rule is neat, the heart, lung, abdomen examination no abnormality seen, internal rectum and swollen thing, red tongue with yellow fur, stringy pulse.Blood, urine, just conventional normal, electrocardiogram, the hepatic and renal function inspection is normal.The colonoscopy no abnormality seen, clinical diagnosis: constipation.Differential diagnosis in tcm: deficiency of YIN dryness of the intestine.
It is oral that medical extract for treating constipation is used in treatment, each 9 grams, and every day 2 times, stool is promptly discharged in medication after 6 hours, after two weeks of medication, stool is soft stool once a day, and each defecation time is within 5 minutes, and dry mouth and throat alleviates, abdominal distention disappears, white and thin fur, and stringy pulse, physico-chemical examination is all normal.

Claims (3)

1, a kind of medical extract for treating constipation is characterized in that, it is the unguentum of being made by the following weight Chinese medicinal raw materials,
Semen Pruni 20-30 part Folium Sennae 20-30 part Semen Arecae 15-20 part
Semen Sesami Nigrum 20-30 part Radix Rehmanniae Preparata 15-20 part Radix Rehmanniae 20-30 part
Radix Scrophulariae 20-25 part Radix Angelicae Sinensis 15-20 part Poria 20-25 part
Radix Glycyrrhizae 10-15 part Mel 20-25 part Cera Flava 20-25 part.
2, medical extract for treating constipation according to claim 1 is characterized in that, the weight proportion of described raw material of Chinese medicine is:
15 parts of 20 portions of Semen Arecaes of 20 portions of Folium Sennae of Semen Pruni
20 parts in 15 parts of Radix Rehmanniae of 20 parts of Radix Rehmanniaes Preparata of Semen Sesami Nigrum
20 parts in 15 parts of Poria of 20 parts of Radix Angelicae Sinensis of Radix Scrophulariae
20 parts in 20 parts of Cera Flavas of 10 parts of Mel of Radix Glycyrrhizae
3, medical extract for treating constipation according to claim 1 is characterized in that, the weight proportion of described raw material of Chinese medicine is:
20 parts of 30 portions of Semen Arecaes of 30 portions of Folium Sennae of Semen Pruni
30 parts in 20 parts of Radix Rehmanniae of 30 parts of Radix Rehmanniaes Preparata of Semen Sesami Nigrum
25 parts in 20 parts of Poria of 25 parts of Radix Angelicae Sinensis of Radix Scrophulariae
25 parts in 25 parts of Cera Flavas of 15 parts of Mel of Radix Glycyrrhizae.
CN98102653A 1998-06-26 1998-06-26 Medical extract for treating constipation Expired - Fee Related CN1062478C (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104042819A (en) * 2014-06-10 2014-09-17 南通德安化工有限公司 Traditional Chinese medicine formula with effect of relaxing bowels

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
吉林中医药1989/12 1989.1.1 李有田 当归补血汤加味治疗产后便秘19例 *

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