CN106237164A

CN106237164A - A kind of compositions treating dental caries

Info

Publication number: CN106237164A
Application number: CN201610861412.3A
Authority: CN
Inventors: 母先俊
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-09-29
Filing date: 2016-09-29
Publication date: 2016-12-21

Abstract

The present invention relates to field of medicaments, be specifically related to a kind of compositions treating dental caries；It is made up of following raw material by weight: crow bubble tree root 20～30, Flos Lonicerae 8～13, Folium Allii tuberosi 5～9, Oryza glutinosa water 15～25；Medicinal liquid is instilled canthus, within one day, drips once, each 2～3, during dripping, after Medical cotton or medical napkin being soaked with medicinal liquid, clog nostril 5～8min；The present invention can cure dental caries quickly, thoroughly, without operation, in the case of human body not being caused damage, is directly forced out from internal by insect, and treatment time is short, and cure rate is high, has no side effect, and cost of material is low, and Therapeutic Method is simple.

Description

A kind of compositions treating dental caries

Technical field

The present invention relates to field of medicaments, be specifically related to a kind of compositions treating dental caries.

Background technology

Dental caries is commonly called as dental caries, decayed tooth, is bacterial disease, even can cause tooth with secondary pulpitis and periapical periodontitis Groove bone and inflammation of jaws, as treated not in time, pathological changes continues development, forms cavity, destroys disappearance eventually to corona completely, its development Final result be loss of tooth, dental caries feature is that sickness rate is high, and distribution is wide, is the main commonly encountered diseases in oral cavity, be also the mankind One of universal disease, it is listed as the big keypoint control disease of the mankind three with tumor and cardiovascular disease by World Health Organization (WHO) Sick.

In the prior art, treatment dental caries typically use 1, root canal method: with root canal special equipment by thoroughly Remove the dental pulp and the dentin of infection and toxic decomposition products infected, through root canal irrigation, sterilization, be filled with the most again Cavity, carries out infecting to prevent antibacterial from entering root pipe and cavity, the method complex operation, easily recurs, can only be temporary transient clear Except antibacterial and harmful substance；2, fissure blockade method: coat a kind of harmless and can self-solidifying in the cross nest ditch of tooth Synthetic organic polymer resin, during liquid, resin can penetrate in the nest ditch of dental surface, is then passed through after illumination solidifying, By the method smearing resin, solidify after illumination, it is impossible to removing the tooth worm in tooth, can only repair surface, index is not Effect a permanent cure.

Owing to the method for doctor trained in Western medicine is costly, and process is loaded down with trivial details, and easily recurrence has side effects, the most also can shadow Ringing the normal feed to patient, so increasing researcher has navigated to low cost, effect stability, in having no side effect Inside medicine field, it is little that tcm therapy has side effect, and anti-recurrence rate is effective, can stablize the state of an illness, indiffusible feature so that its Quick application and popularization has been obtained in dental caries field, but, owing to traditional Chinese medical science formula of the prior art is unreasonable, material composition Incorrect, Therapeutic Method lack of standardization, cause Chinese traditional treatment to be difficult to dental caries and thoroughly cure, and the most not yet find can be short The Chinese medicine formula thoroughly curing dental caries in time occurs.

Summary of the invention

The present invention solves above-mentioned technical problem, it is provided that a kind of compositions treating dental caries.

Realize particular by techniques below scheme:

A kind of compositions treating dental caries, is made up of following raw material by weight: crow bubble tree root 20～30, Flos Lonicerae 8～13, Folium Allii tuberosi 5～9, Oryza glutinosa water 15～25；

Medicinal liquid is instilled canthus, within one day, drips once, each 2～3, during dripping, with medicinal liquid by Medical cotton or After the medical napkin of person soaks, clog nostril 5～8min.

Preferably, it is made up of following raw material by weight: crow bubble tree root 25, Flos Lonicerae 11, Folium Allii tuberosi 7, Oryza glutinosa water 20.

Further, described medicinal liquid, it is the mixed extract mixing that crow is steeped tree root extracting solution, Flos Lonicerae and Folium Allii tuberosi, stirs Mix uniformly, be heated to seething with excitement after 5～8min, be cooled to room temperature, then after mixing homogeneously with the Oryza glutinosa water of formula ratio, mix thoroughly, obtain Medicinal liquid.

Further, described crow bubble tree root extracting solution, after being harvesting fresh crow bubble tree root, retain root hair, wash with water The earth of epidermis, is cut into the section that thickness is 1～2cm, and the water of 2.5～3 times of addition section gross mass, at a simmer front very hot oven is decocted Boil, keep slight boiling condition 100～140min with little fire after boiling, filter, obtain filtrate for the first time, the filtering residue quality that addition is filtered The water of 1.5～1.8 times, at a simmer front very hot oven decocts, and keeps slight boiling condition 60～80min with little fire, filters, obtain filter for the second time after boiling Liquid, mixes the filtering residue of twice filtration, smashs 25～30min to pieces, adds water to just not have filtering residue, places 15～20h, filter the Three filtrates, by the mixing of three filtrates, obtain mixing filtrate, add the ethanol of 1～1.3 times of mixing filtrate volume, airtight put Put 44～46h, after decompression distillation, i.e. obtain crow bubble tree root extracting solution.

Further, described Flos Lonicerae and the mixed extract of Folium Allii tuberosi, be Flos Lonicerae and the Folium Allii tuberosi weighing formula ratio, mixed Close, add the water of its mixing 0.3～0.5 times of gross mass, pulverize 12～15min by juice extractor, filter, concentrate the filtrate to The 1/3 of filtrate volume,.

Further, described Oryza glutinosa water, is the water being initially charged and not having Oryza glutinosa, after stirring evenly, removes the floating thing on surface, mistake Filter, the water of 1.5～2 times of addition Oryza glutinosa quality, after soaking 25～35min, it is polished into slurry by beater, crosses 80～100 Mesh sieve, i.e. obtains Oryza glutinosa water.

Further, described decompression distillation, its force value is 0.035～0.04Mpa.

The formula material used the present invention below is described further:

Crow bubble tree root: tool heat-clearing and toxic substances removing, expelling wind and removing dampness, removing heat from blood, hemostasis, effect of synthetism, is used for treating caries pain, periodontal Inflammation, gingiva pain.

Flos Lonicerae: have antibacterial, antiviral, antipyretic, antiinflammatory, function of gallbladder promoting, protect the liver, antioxidation, blood fat reducing, hemostasis, immunity are adjusted The effects such as joint.

In sum, the beneficial effects of the present invention is: the present invention can cure dental caries quickly, thoroughly, without operation, In the case of human body not being caused damage, directly being forced out from internal by insect, treatment time is short, and cure rate is high, has no side effect, Cost of material is low, and Therapeutic Method is simple.

Detailed description of the invention

Below the detailed description of the invention of the present invention is described in further detail, but the invention is not limited in that these are real Execute mode, any improvement on the present embodiment essence spirit or replacement, still fall within the claims in the present invention required for protection Scope.

Embodiment 1

A kind of compositions treating dental caries, is made up of following raw material by weight: crow bubble tree root 20kg, Flos Lonicerae 8kg, Folium Allii tuberosi 5kg, Oryza glutinosa water 15kg.

Medicinal liquid is instilled canthus, within one day, drips once, each 2～3, during dripping, with medicinal liquid by Medical cotton or After the medical napkin of person soaks, clog nostril 5min.

Described medicinal liquid, is the mixed extract mixing that crow is steeped tree root extracting solution, Flos Lonicerae and Folium Allii tuberosi, stirs, It is heated to seething with excitement after 5min, is cooled to room temperature, then after mixing homogeneously with the Oryza glutinosa water of formula ratio, mix thoroughly, obtain medicinal liquid.

Described crow bubble tree root extracting solution, after being harvesting fresh crow bubble tree root, retains root hair, washes the mud of epidermis with water Soil, is cut into the section that thickness is 1～2cm, and the water of 2.5 times of addition section gross mass, at a simmer front very hot oven decocts, and uses little fire after boiling Keep slight boiling condition 100min, filter, obtain for the first time filtrate, add the water of 1.5 times of the filtering residue quality filtered, at a simmer before anxious Fire decocts, and keeps slight boiling condition 60min with little fire, filters, obtain second time filtrate, mixed by the filtering residue of twice filtration, smash after boiling Broken 25min, adds water to just not have filtering residue, places 15h, filters to obtain third time filtrate, by three filtrate mixing, obtains mixing filter Liquid, adds the ethanol of 1 times that mixes filtrate volume, airtight placement 44h, after decompression distillation, i.e. obtains crow bubble tree root extracting solution.

Described Flos Lonicerae and the mixed extract of Folium Allii tuberosi, be Flos Lonicerae and the Folium Allii tuberosi weighing formula ratio, mixing, adds it The water of mixing 0.3 times of gross mass, pulverizes 12min by juice extractor, filters, and concentrates the filtrate to the 1/3 of filtrate volume, i.e. Can.

Described Oryza glutinosa water, is the water being initially charged and not having Oryza glutinosa, after stirring evenly, removes the floating thing on surface, filters, adds The water of 1.5 times of Oryza glutinosa quality, after soaking 25min, is polished into slurry by beater, crosses 80 mesh sieves, i.e. obtain Oryza glutinosa water.

Described decompression distillation, its force value is 0.035Mpa.

Embodiment 2

A kind of compositions treating dental caries, is made up of following raw material by weight: crow bubble tree root 30kg, Flos Lonicerae 13kg, Folium Allii tuberosi 9kg, Oryza glutinosa water 25kg；

Medicinal liquid is instilled canthus, within one day, drips once, each 2～3, during dripping, with medicinal liquid by Medical cotton or After the medical napkin of person soaks, clog nostril 8min.

Described medicinal liquid, is the mixed extract mixing that crow is steeped tree root extracting solution, Flos Lonicerae and Folium Allii tuberosi, stirs, It is heated to seething with excitement after 8min, is cooled to room temperature, then after mixing homogeneously with the Oryza glutinosa water of formula ratio, mix thoroughly, obtain medicinal liquid.

Described crow bubble tree root extracting solution, after being harvesting fresh crow bubble tree root, retains root hair, washes the mud of epidermis with water Soil, is cut into the section that thickness is 1～2cm, the water of 3 times of addition section gross mass, and at a simmer front very hot oven decocts, with little fire guarantor after boiling Hold slight boiling condition 140min, filter, obtain filtrate for the first time, the water of 1.8 times of the filtering residue quality that addition is filtered, at a simmer front very hot oven Decoct, keep slight boiling condition 80min with little fire after boiling, filter, obtain second time filtrate, the filtering residue of twice filtration is mixed, smashs to pieces 30min, adds water to just not have filtering residue, places 20h, filters to obtain third time filtrate, by three filtrate mixing, obtains mixing filter Liquid, adds the ethanol of .3 times that mixes filtrate volume, airtight placement 46h, after decompression distillation, i.e. obtains crow bubble tree root extracting solution.

Described Flos Lonicerae and the mixed extract of Folium Allii tuberosi, be Flos Lonicerae and the Folium Allii tuberosi weighing formula ratio, mixing, adds it The water of mixing 0.5 times of gross mass, pulverizes 15min by juice extractor, filters, and concentrates the filtrate to the 1/3 of filtrate volume, i.e. Can.

Described Oryza glutinosa water, is the water being initially charged and not having Oryza glutinosa, after stirring evenly, removes the floating thing on surface, filters, adds The water of 2 times of Oryza glutinosa quality, after soaking 35min, is polished into slurry by beater, crosses 100 mesh sieves, i.e. obtain Oryza glutinosa water.

Described decompression distillation, its force value is 0.04Mpa.

Embodiment 3

A kind of compositions treating dental caries, is made up of following raw material by weight: crow bubble tree root 25kg, Flos Lonicerae 11kg, Folium Allii tuberosi 7kg, Oryza glutinosa water 20kg；

Medicinal liquid is instilled canthus, within one day, drips once, each 2～3, during dripping, with medicinal liquid by Medical cotton or After the medical napkin of person soaks, clog nostril 6min.

Described medicinal liquid, is the mixed extract mixing that crow is steeped tree root extracting solution, Flos Lonicerae and Folium Allii tuberosi, stirs, It is heated to seething with excitement after 7min, is cooled to room temperature, then after mixing homogeneously with the Oryza glutinosa water of formula ratio, mix thoroughly, obtain medicinal liquid.

Described crow bubble tree root extracting solution, after being harvesting fresh crow bubble tree root, retains root hair, washes the mud of epidermis with water Soil, is cut into the section that thickness is 1～2cm, and the water of 2.8 times of addition section gross mass, at a simmer front very hot oven decocts, and uses little fire after boiling Keep slight boiling condition 120min, filter, obtain for the first time filtrate, add the water of 1.7 times of the filtering residue quality filtered, at a simmer before anxious Fire decocts, and keeps slight boiling condition 70min with little fire, filters, obtain second time filtrate, mixed by the filtering residue of twice filtration, smash after boiling Broken 28min, adds water to just not have filtering residue, places 18h, filters to obtain third time filtrate, by three filtrate mixing, obtains mixing filter Liquid, adds the ethanol of 1.1 times that mix filtrate volume, airtight placement 45h, after decompression distillation, i.e. obtains crow bubble tree root extracting solution.

Described Flos Lonicerae and the mixed extract of Folium Allii tuberosi, be Flos Lonicerae and the Folium Allii tuberosi weighing formula ratio, mixing, adds it The water of mixing 0.4 times of gross mass, pulverizes 13min by juice extractor, filters, and concentrates the filtrate to the 1/3 of filtrate volume, i.e. Can.

Described Oryza glutinosa water, is the water being initially charged and not having Oryza glutinosa, after stirring evenly, removes the floating thing on surface, filters, adds The water of 1.8 times of Oryza glutinosa quality, after soaking 30min, is polished into slurry by beater, crosses 90 mesh sieves, i.e. obtain Oryza glutinosa water.

Described decompression distillation, its force value is 0.038Mpa.

Embodiment 4

A kind of compositions treating dental caries, is made up of following raw material by weight: crow bubble tree root 30kg, Flos Lonicerae 8kg, Folium Allii tuberosi 9kg, Oryza glutinosa water 20kg；

Described crow bubble tree root extracting solution, after being harvesting fresh crow bubble tree root, retains root hair, washes the mud of epidermis with water Soil, is cut into the section that thickness is 1～2cm, the water of 3 times of addition section gross mass, and at a simmer front very hot oven decocts, with little fire guarantor after boiling Hold slight boiling condition 100min, filter, obtain filtrate for the first time, the water of 1.8 times of the filtering residue quality that addition is filtered, at a simmer front very hot oven Decoct, keep slight boiling condition 60min with little fire after boiling, filter, obtain second time filtrate, the filtering residue of twice filtration is mixed, smashs to pieces 30min, adds water to just not have filtering residue, places 20h, filters to obtain third time filtrate, by three filtrate mixing, obtains mixing filter Liquid, adds the ethanol of 1 times that mixes filtrate volume, airtight placement 46h, after decompression distillation, i.e. obtains crow bubble tree root extracting solution.

Described Flos Lonicerae and the mixed extract of Folium Allii tuberosi, be Flos Lonicerae and the Folium Allii tuberosi weighing formula ratio, mixing, adds it The water of mixing 0.3 times of gross mass, pulverizes 15min by juice extractor, filters, and concentrates the filtrate to the 1/3 of filtrate volume, i.e. Can.

Described Oryza glutinosa water, is the water being initially charged and not having Oryza glutinosa, after stirring evenly, removes the floating thing on surface, filters, adds The water of 2 times of Oryza glutinosa quality, after soaking 35min, is polished into slurry by beater, crosses 80 mesh sieves, i.e. obtain Oryza glutinosa water.

Described decompression distillation, its force value is 0.04Mpa.

Embodiment 5

A kind of compositions treating dental caries, is made up of following raw material by weight: crow bubble tree root 30, Flos Lonicerae 10, Folium Allii tuberosi 9, Oryza glutinosa water 15；

Described medicinal liquid, is the mixed extract mixing that crow is steeped tree root extracting solution, Flos Lonicerae and Folium Allii tuberosi, stirs, It is heated to seething with excitement after 6min, is cooled to room temperature, then after mixing homogeneously with the Oryza glutinosa water of formula ratio, mix thoroughly, obtain medicinal liquid.

Described crow bubble tree root extracting solution, after being harvesting fresh crow bubble tree root, retains root hair, washes the mud of epidermis with water Soil, is cut into the section that thickness is 1～2cm, the water of 3 times of addition section gross mass, and at a simmer front very hot oven decocts, with little fire guarantor after boiling Hold slight boiling condition 100min, filter, obtain filtrate for the first time, the water of 1.8 times of the filtering residue quality that addition is filtered, at a simmer front very hot oven Decoct, keep slight boiling condition 60～80min with little fire after boiling, filter, obtain second time filtrate, the filtering residue of twice filtration is mixed, Smash 30min to pieces, add water to just not have filtering residue, place 15h, filter to obtain third time filtrate, by three filtrate mixing, mixed Filtrate, adds the ethanol of 1.3 times that mix filtrate volume, airtight placement 44h, after decompression distillation, i.e. obtains crow bubble tree root extraction Liquid.

Described Flos Lonicerae and the mixed extract of Folium Allii tuberosi, be Flos Lonicerae and the Folium Allii tuberosi weighing formula ratio, mixing, adds it The water of mixing 0.5 times of gross mass, pulverizes 12min by juice extractor, filters, and concentrates the filtrate to the 1/3 of filtrate volume, i.e. Can.

Described Oryza glutinosa water, is the water being initially charged and not having Oryza glutinosa, after stirring evenly, removes the floating thing on surface, filters, adds The water of 2 times of Oryza glutinosa quality, after soaking 25min, is polished into slurry by beater, crosses 100 mesh sieves, i.e. obtain Oryza glutinosa water.

Described decompression distillation, its force value is 0.038Mpa.

Experimental example

1, toxicity test:

1.1, medicine: use the Chinese medicine formula of embodiment 1～5.

1.2, subjects: choosing the white mice 120 that health is healthy, male and female half and half, body weight 10～15g, people Breeding observing 3d under work illumination 12h, ventilation condition good situations, is randomly divided into 6 groups, and one of which is blank examination group, gives Feed is forbidden in the front 12h of medicine and administration for latter 4 hours, but can't help water.

Other 5 groups of white mice are gavaged dosage except blank elements is other and are respectively 600ml/kg's by 1.3, method: after 3d The preparation of embodiment 1～5, observes 7d.

1.3, result: Continuous Observation 7d, whole white mice are all good for alive and the whole spirit of white mice, appetite, secretions, exhale The aspects such as suction, eye all do not observe exception, and by experiment mice and control group mice after analysing, each histoorgan is without obvious sense Difference, cores, liver, spleen, lung, kidney and intestinal make pathological section also without significantly different, and increased dosage amount, same method gavages embodiment The prescription drug of 1～5, whole mices are still strong to live, and compares without exception with matched group, illustrates that this Chinese medicine formula is to mice safety Nontoxic.

2, effect experimental: the present invention takes safety, easy and simple to handle, evident in efficacy, is the effective medicine that can thoroughly cure dental caries Thing, and proved by clinical data, the relevant clinical data of the present invention is as follows:

2.1, Lee so-and-so, man, 59 years old, have a toothache for a long time, with red swelling of gingiva, above employing eye drip angle and by Medical cotton or Person's medical napkin dip in liquid medicine, after clogging nostril, after a few minutes, insect runs out of from canthus, and continuous 1 week according to said method operates After, toothache, red swelling of gingiva symptom completely without, tooth is wiped up by worm.

2.2, Zhang, female, 45 years old, toothache, hospital diagnosis for there being periodontitis, gingival hemorrhage, above employing eye drip angle with With Medical cotton or medical napkin dip in liquid medicine, after clogging nostril, after a few minutes, insect runs out of from canthus, and continuous 1 week presses The method operation after, symptom completely without, tooth is wiped up by worm.

2.3, Liu so-and-so, man, 32 years old, toothache, pulpitis, alveolar bone inflammation, a left side is blushed swollen, eye drip angle and use above employing Medical cotton or medical napkin dip in liquid medicine, after clogging nostril, after a few minutes, insect runs out of from canthus, and continuous 10d is according to said method After operation, symptom completely without, tooth is wiped up by worm.

2.4, blue so-and-so, man, 50 years old, dental caries, red swelling of gingiva, toothache, above employing eye drip angle and by Medical cotton or Medical napkin dip in liquid medicine, after clogging nostril, after a few minutes, insect runs out of from canthus, and after continuous 5d according to said method operates, symptom is complete Nothing, tooth is wiped up by worm.

Claims

1. the compositions treating dental caries, it is characterised in that be made up of following raw material by weight: crow bubble tree root 20～ 30, Flos Lonicerae 8～13, Folium Allii tuberosi 5～9, Oryza glutinosa water 15～25；

Medicinal liquid is instilled canthus, within one day, drips once, each 2～3, during dripping, with medicinal liquid by Medical cotton or doctor After soaking with napkin, clog nostril 5～8min.

2. the compositions treating dental caries as claimed in claim 1, it is characterised in that by following raw material group by weight Become: crow bubble tree root 25, Flos Lonicerae 11, Folium Allii tuberosi 7, Oryza glutinosa water 20.

3. the compositions treating dental caries as claimed in claim 1, it is characterised in that described medicinal liquid, is crow to be steeped tree root carry Take the mixed extract mixing of liquid, Flos Lonicerae and Folium Allii tuberosi, stir, be heated to seething with excitement after 5～8min, be cooled to room temperature, then After mixing homogeneously with the Oryza glutinosa water of formula ratio, mix thoroughly, obtain medicinal liquid.

4. the compositions treating dental caries as claimed in claim 3, it is characterised in that described crow bubble tree root extracting solution, is to adopt After plucking fresh crow bubble tree root, retaining root hair, wash the earth of epidermis with water, be cut into the section that thickness is 1～2cm, addition is cut The water of 2.5～3 times of sheet gross mass, at a simmer front very hot oven decocts, and keeps slight boiling condition 100～140min with little fire, filter after boiling, Obtaining first time filtrate, the water of 1.5～1.8 times of the filtering residue quality that addition is filtered, at a simmer front very hot oven decocts, with little fiery guarantor after boiling Hold slight boiling condition 60～80min, filter, obtain second time filtrate, the filtering residue of twice filtration is mixed, smashs 25～30min to pieces, add water To just not having filtering residue, place 15～20h, filter to obtain third time filtrate, by three filtrate mixing, obtain mixing filtrate, add The ethanol of 1～1.3 times of mixing filtrate volume, airtight placement 44～46h, after decompression distillation, i.e. obtain crow bubble tree root extracting solution.

5. the compositions treating dental caries as claimed in claim 3, it is characterised in that described Flos Lonicerae and the mixing of Folium Allii tuberosi carry Take liquid, be Flos Lonicerae and the Folium Allii tuberosi weighing formula ratio, mixing, add the water of its mixing 0.3～0.5 times of gross mass, by squeezing Juice machine pulverizes 12～15min, filters, concentrates the filtrate to the 1/3 of filtrate volume,.

6. the compositions of the treatment dental caries as described in claim 1 or 2 or 3, it is characterised in that described Oryza glutinosa water, is first to add Enter the water that can not have Oryza glutinosa, after stirring evenly, remove the floating thing on surface, filter, the water of 1.5～2 times of addition Oryza glutinosa quality, soaks After 25～35min, it is polished into slurry by beater, crosses 80～100 mesh sieves, i.e. obtain Oryza glutinosa water.

7. the compositions treating dental caries as claimed in claim 4, it is characterised in that described decompression distillation, its force value is 0.035～0.04Mpa.