CN106236089A - A kind of implanted multi-functional microneedle array brain electrode - Google Patents
A kind of implanted multi-functional microneedle array brain electrode Download PDFInfo
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- CN106236089A CN106236089A CN201610817579.XA CN201610817579A CN106236089A CN 106236089 A CN106236089 A CN 106236089A CN 201610817579 A CN201610817579 A CN 201610817579A CN 106236089 A CN106236089 A CN 106236089A
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- electrode
- detection electrode
- brain
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- pulse stimulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/685—Microneedles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6868—Brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0526—Head electrodes
- A61N1/0529—Electrodes for brain stimulation
- A61N1/0539—Anchoring of brain electrode systems, e.g. within burr hole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Physics & Mathematics (AREA)
- Surgery (AREA)
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- Neurology (AREA)
- Pathology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Optics & Photonics (AREA)
- Electrotherapy Devices (AREA)
Abstract
The invention discloses a kind of implanted multi-functional microneedle array brain electrode, including outside framework, pcb board, electrode loading plate, electric pulse stimulation electrode, brain electro-detection electrode and electrochemical detection electrode, the lower surface of described outside framework is installed with electrode loading plate, and the lower surface of electrode loading plate is provided with electric pulse stimulation electrode, brain electro-detection electrode and electrochemical detection electrode, it is configured to electrod-array;Wire connecting PCB board is passed through on the top of described electric pulse stimulation electrode, described brain electro-detection electrode and described electrochemical detection electrode, and pcb board uses the mode of gluing to be fixed on the upside of outside framework;The outside of described electric pulse stimulation electrode, described brain electro-detection electrode and described electrochemical detection electrode is all enclosed with up big and down small tapered oversheath, and to post thickness be 0.15mm 0.35mm plaster in the bottom of oversheath.The present invention is possible not only to reduce hair and impacts testing result, meanwhile, effectively carries out anti-inflammation to thrusting position, thus prevents from scalp is caused damage.
Description
Technical field
The present invention relates to brain wave acquisition, specifically a kind of implanted multi-functional microneedle array brain electrode.
Background technology
In recent years, continuous along with MEMS (MEMS:Micro-Electro-MechanicalSystems) technology
Development and maturation so that the microsystem range of application such as microelectronic device and microsensor constantly expands, and is widely used to the people
With fields such as, medical science, military affairs.The research of probe microelectrode based on micro fabrication is developed rapidly.Microelectrode structure
Mainly having planar microelectrode and different planar microelectrode and planar microelectrode is assembled into the microelectrode of array configuration, these are different
The microelectrode of structure all has respective feature.
Traditional electroencephalogramsignal signal collection equipment is based on wet electrode.User using before electroencephalogramsignal signal collection equipment,
Have to coating conductive paste, to reduce the impact of the horny layer EEG signals on collecting.Electrode is also easily used by hair simultaneously
Impact, for piercing electrode, scalp wound surface is the most preferably processed.
Summary of the invention
It is an object of the invention to provide a kind of implanted multi-functional microneedle array brain electrode, to solve above-mentioned background technology
The problem of middle proposition.
For achieving the above object, the present invention provides following technical scheme: a kind of implanted multi-functional microneedle array brain electrode,
Including outside framework, pcb board, electrode loading plate, electric pulse stimulation electrode, brain electro-detection electrode and electrochemical detection electrode, housing
The lower surface of frame is installed with electrode loading plate, and the lower surface of electrode loading plate is provided with electric pulse stimulation electrode, brain electricity
Detecting electrode and electrochemical detection electrode, be configured to electrod-array;Electric pulse stimulation electrode, brain electro-detection electrode and electrochemistry inspection
Wire connecting PCB board is passed through on the top surveying electrode, and pcb board uses the mode of gluing to be fixed on the upside of outside framework;
Preferably, the outside of electric pulse stimulation electrode, brain electro-detection electrode and electrochemical detection electrode is all enclosed with up big and down small
Tapered oversheath, and the bottom of oversheath posts the plaster that thickness is 0.15mm-0.35mm.
Preferably, the bottom of electric pulse stimulation electrode, brain electro-detection electrode and electrochemical detection electrode all extends to plaster
Bottom outside 0.05mm-0.15mm.
Compared with prior art, the invention has the beneficial effects as follows: the present invention is possible not only to reduce hair and makes testing result
Become impact, increase plaster formula structure simultaneously so that overall can effectively resist thrusting position in the process thrusting scalp
Bacterium antiinflammatory, thus prevent from scalp is caused damage.
Accompanying drawing explanation
Fig. 1 is the structural representation of a kind of implanted of the present invention multi-functional microneedle array brain electrode.
Detailed description of the invention
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Describe, it is clear that described embodiment is only a part of embodiment of the present invention rather than whole embodiments wholely.Based on
Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under not making creative work premise
Embodiment, broadly falls into the scope of protection of the invention.
Refer to Fig. 1, in the embodiment of the present invention, a kind of implanted multi-functional microneedle array brain electrode, including outside framework 1,
Pcb board 2, electrode loading plate 3, electric pulse stimulation electrode 4, brain electro-detection electrode 5 and electrochemical detection electrode 6, outside framework 1 time
Surface is installed with electrode loading plate 3, and the lower surface of electrode loading plate 3 is provided with electric pulse stimulation electrode 4, brain electro-detection
Electrode 5 and electrochemical detection electrode 6, be configured to electrod-array;Electric pulse stimulation electrode 4, brain electro-detection electrode 5 and electrochemistry inspection
Wire connecting PCB board 2 is passed through on the top surveying electrode 6, and pcb board 2 uses the mode of gluing to be fixed on the upside of outside framework 1;Electricity
The outside of impulse stimulation electrode 4, brain electro-detection electrode 5 and electrochemical detection electrode 6 be all enclosed with up big and down small tapered outside
Sheath 7, and the bottom of oversheath 7 posts the plaster 8 that thickness is 0.15mm-0.35mm;Electric pulse stimulation electrode 4, brain electro-detection
The bottom of electrode 5 and electrochemical detection electrode 6 all extends to plaster 8 bottom outside 0.05mm-0.15mm.
The operation principle of the present invention is: during work, and oversheath 7 uses isolation material to make, and utilizes oversheath 7 to prevent hair
Interfering electrode, plaster 8 is posted in the bottom of oversheath 7, and plaster 8 uses the ointment with bactericidal action to make, and utilizes medicine
Patch 8 is possible to prevent electrode to thrust the wound infection of position, thus avoids scalp damage occur.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of the spirit or essential attributes of the present invention, it is possible to realize the present invention in other specific forms.Therefore, no matter
From the point of view of which point, all should regard embodiment as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit requires rather than described above limits, it is intended that all by fall in the implication of equivalency and scope of claim
Change is included in the present invention.Should not be considered as limiting involved claim by any reference in claim.
Although moreover, it will be appreciated that this specification is been described by according to embodiment, but the most each embodiment only wraps
Containing an independent technical scheme, this narrating mode of description is only that for clarity sake those skilled in the art should
Description can also be formed those skilled in the art through appropriately combined as an entirety, the technical scheme in each embodiment
May be appreciated other embodiments.
Claims (3)
1. an implanted multi-functional microneedle array brain electrode, it is characterised in that include a kind of multi-functional microneedle array of implanted
Brain electrode, including outside framework, pcb board, electrode loading plate, electric pulse stimulation electrode, brain electro-detection electrode and Electrochemical Detection electricity
Pole, the lower surface of described outside framework is installed with electrode loading plate, and the lower surface of electrode loading plate is provided with electric pulse thorn
Swash electrode, brain electro-detection electrode and electrochemical detection electrode, be configured to electrod-array;Described electric pulse stimulation electrode, described brain
Wire connecting PCB board is passed through on the top of electro-detection electrode and described electrochemical detection electrode, and pcb board uses the mode of gluing admittedly
It is scheduled on the upside of outside framework.
Implanted the most according to claim 1 multi-functional microneedle array brain electrode, it is characterised in that: described electric pulse stimulation
The outside of electrode, described brain electro-detection electrode and described electrochemical detection electrode is all enclosed with up big and down small tapered outer protect
Overlap, and the plaster that thickness is 0.15mm-0.35mm is posted in the bottom of oversheath.
Implanted the most according to claim 1 multi-functional microneedle array brain electrode, it is characterised in that: described electric pulse stimulation
The bottom of electrode, described brain electro-detection electrode and described electrochemical detection electrode all extends to plaster bottom outside 0.05mm-
0.15mm。
Priority Applications (1)
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CN201610817579.XA CN106236089A (en) | 2016-09-13 | 2016-09-13 | A kind of implanted multi-functional microneedle array brain electrode |
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CN201610817579.XA CN106236089A (en) | 2016-09-13 | 2016-09-13 | A kind of implanted multi-functional microneedle array brain electrode |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111096742A (en) * | 2019-12-13 | 2020-05-05 | 开封市学国生物科技有限公司 | 3D chronic brain electrode adjusting device for experiments |
CN111631813A (en) * | 2020-05-27 | 2020-09-08 | 武汉联影智融医疗科技有限公司 | Automatic sequencing method, sequencing system, equipment and computer-readable storage medium for implantable electrodes |
CN117770822A (en) * | 2024-01-23 | 2024-03-29 | 中国科学院半导体研究所 | Patch device based on dry-wet combined microneedle electrode |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102334989A (en) * | 2011-07-29 | 2012-02-01 | 上海交通大学 | Different-plane microneedle array brain electrical dry electrode with controllable puncturing depth |
CN102755691A (en) * | 2012-06-19 | 2012-10-31 | 吉林大学 | Medical high-sensitivity micro needle array electrode |
CN105561469A (en) * | 2015-12-12 | 2016-05-11 | 西安交通大学 | Implanted multifunctional double-side micro brain electrode array chip |
CN105769182A (en) * | 2016-02-22 | 2016-07-20 | 武汉智普天创科技有限公司 | Electroencephalogram signal wireless collecting system |
-
2016
- 2016-09-13 CN CN201610817579.XA patent/CN106236089A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102334989A (en) * | 2011-07-29 | 2012-02-01 | 上海交通大学 | Different-plane microneedle array brain electrical dry electrode with controllable puncturing depth |
CN102755691A (en) * | 2012-06-19 | 2012-10-31 | 吉林大学 | Medical high-sensitivity micro needle array electrode |
CN105561469A (en) * | 2015-12-12 | 2016-05-11 | 西安交通大学 | Implanted multifunctional double-side micro brain electrode array chip |
CN105769182A (en) * | 2016-02-22 | 2016-07-20 | 武汉智普天创科技有限公司 | Electroencephalogram signal wireless collecting system |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111096742A (en) * | 2019-12-13 | 2020-05-05 | 开封市学国生物科技有限公司 | 3D chronic brain electrode adjusting device for experiments |
CN111631813A (en) * | 2020-05-27 | 2020-09-08 | 武汉联影智融医疗科技有限公司 | Automatic sequencing method, sequencing system, equipment and computer-readable storage medium for implantable electrodes |
CN117770822A (en) * | 2024-01-23 | 2024-03-29 | 中国科学院半导体研究所 | Patch device based on dry-wet combined microneedle electrode |
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