CN106195331A - A kind of multichannel injection valve - Google Patents
A kind of multichannel injection valve Download PDFInfo
- Publication number
- CN106195331A CN106195331A CN201610587541.8A CN201610587541A CN106195331A CN 106195331 A CN106195331 A CN 106195331A CN 201610587541 A CN201610587541 A CN 201610587541A CN 106195331 A CN106195331 A CN 106195331A
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- China
- Prior art keywords
- connecting tube
- pipe
- switching
- shell
- injection valve
- Prior art date
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Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K11/00—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves
- F16K11/02—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit
- F16K11/06—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements
- F16K11/065—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements with linearly sliding closure members
- F16K11/0655—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements with linearly sliding closure members with flat slides
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K19/00—Arrangements of valves and flow lines specially adapted for mixing fluids
- F16K19/006—Specially adapted for faucets
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K27/00—Construction of housing; Use of materials therefor
- F16K27/04—Construction of housing; Use of materials therefor of sliding valves
- F16K27/044—Construction of housing; Use of materials therefor of sliding valves slide valves with flat obturating members
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K3/00—Gate valves or sliding valves, i.e. cut-off apparatus with closing members having a sliding movement along the seat for opening and closing
- F16K3/30—Details
- F16K3/314—Forms or constructions of slides; Attachment of the slide to the spindle
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K31/00—Actuating devices; Operating means; Releasing devices
- F16K31/02—Actuating devices; Operating means; Releasing devices electric; magnetic
- F16K31/04—Actuating devices; Operating means; Releasing devices electric; magnetic using a motor
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L39/00—Joints or fittings for double-walled or multi-channel pipes or pipe assemblies
- F16L39/04—Joints or fittings for double-walled or multi-channel pipes or pipe assemblies allowing adjustment or movement
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
- G01N35/085—Flow Injection Analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Multiple-Way Valves (AREA)
Abstract
One multichannel injection valve of the present invention includes shell (132), and its outer surface is provided with at least two outages (137), is internally provided with spool (127)；And motor (129), its output shaft is fixed with described spool (127) by shaft coupling (130)；Wherein, described shell (132) is arranged on shaft coupling (130) by bearing, described spool (127) is provided with at least two amount of being ranked lumen pores, and described spool (127) can be according to motor (129) the rotation direction switching quantitative lumen pore of odd row, the opening and closing of the quantitative lumen pore of even rows.When the present invention works shell and relative rotor displacement is less, repeatedly continuous sample introduction residual contamination little, the most accurate, functional, with low cost.
Description
Technical field
The present invention relates to the parts of a kind of analytical tool, particularly relate to a kind of valve.
Background technology
Flow Injection Analysis refers to use the spectrophotometer equipped with flow cell, fluorophotometer, atomic absorption spectrophotometry light
The detector analyses such as degree meter and ion meter measure the capacity (sample of the reagent flow (testing sample is included in reagent flow) with flow velocity
Product content) method, i.e. replace beaker and volumetric flask with polyfluortetraethylene pipe or PEEK pipe, be analyzed by flow injection
Method.Having an important link in Flow Injection Analysis System is exactly exactly by testing sample Injection Detector.Traditional
Way is, by six-way valve (the 7725i six-way valve as classical), sample injects analysis system, but along with the progress (high pass of technology
The appearance of amount detector) and the growth of actual demand, especially Flow injection immunoassay system in, production practices often need
Hundreds and thousands of samples will simultaneously accurately be injected high throughput analysis systems, six-way valve used in parallel is extremely complex by producing
Liquid line, the motor driven systems of huge number and high cost, this causes many difficulties to reality application.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of simple in construction, low cost, a kind of multichannel easy and simple to handle are entered
Sample valve.
One multichannel injection valve of the present invention, including shell, its outer surface is provided with at least two outages, is internally provided with valve
Core；And motor, its output shaft is fixed with described spool by shaft coupling；Wherein, described shell is arranged on shaft coupling by bearing
On, described spool is provided with at least two amount of being ranked lumen pores, and described spool can switch the quantitative of odd row according to direction of motor rotation
Lumen pore, the opening and closing of quantitative lumen pore of even rows.
One multichannel injection valve of the present invention, wherein, described motor is program control motor.
One multichannel injection valve of the present invention, wherein, the material of described spool be macromolecule inert matrix material PEEK, PS or
PDMS。
One multichannel injection valve of the present invention, wherein, it is macromolecule inert matrix material PEEK, PS that described shell makes material
And PDMS.
One multichannel injection valve of the present invention, wherein, described shell just the surface of the quantitative lumen pore of spool is provided with shell
Strap, described shell strap is provided with at least at least two outages.
One multichannel injection valve of the present invention, wherein, it is macromolecule inertia composite wood that described shell strap makes material
Material PEEK, PS and PDMS.
One multichannel injection valve of the present invention, wherein, on described spool the number of rated capacity lumen pore be-individual.
One multichannel injection valve of the present invention, wherein, the fluid apertures of described shell is connected with switching pipe；The odd row of described spool
Quantitative lumen pore connect and have odd number connecting tube, the quantitative lumen pore of even rows connects even number connecting tube, and described switching pipe is by cutting
Changing device switching and odd number connecting tube, the connection of even number connecting tube, described switching device includes the first extension fixture, the second expansion
Device, described first extension fixture, the second mutually symmetrical setting of extension fixture, described first extension fixture include the first housing,
Permanent magnet sleeve, guide pin bushing, push rod, electric magnet sleeve, heading；Described one end of first housing is fixed with the inner surface of shell, the
It is fixed with permanent magnet sleeve in one housing, in described permanent magnet sleeve, is set with at least two electric magnet sleeve, described at least two
Individual electric magnet sleeve and permanent magnet sleeve matched in clearance, the electric magnet sleeve after described energising is suspended in permanent magnet by magnetic induction
On sleeve and relative displacement can be produced；Be fixed with guide pin bushing in described at least two electric magnet sleeve, one end of described guide pin bushing with
Two orthogonal hinge are passed through in one end away from opening of first housing, and described guide pin bushing is made up of aluminum alloy materials,
Being provided with push rod in described guide pin bushing, described push rod has ferrous material to make, and described push rod is solid near one end of the opening of the first housing
Surely having heading, described heading can contact with the inner surface of described expanding bar；Described first extension fixture, the second extension fixture
Heading respectively with switching pipe two sides contact, switching pipe and shell chain connection, described odd number connecting tube, even number connecting tube with
One end that switching pipe connects is equipped with flaring connection bucket, and the length near another connection bucket of said two connection bucket is less than
The length away from another connection bucket of two connection buckets.
One multichannel injection valve of the present invention, wherein, the fluid apertures of described shell is connected with switching pipe；The odd row of described spool
Quantitative lumen pore connect and have odd number connecting tube, the quantitative lumen pore of even rows connects even number connecting tube, and described switching pipe is by cutting
Changing device switching and odd number connecting tube, the connection of even number connecting tube；Described switching device includes fixing seat, the first inlet, strange
Number sensor, even number sensor, dustpan-shaped separatory groove；Described fixing seat is connected with described shaft coupling, and fixing seat is by dustpan-shaped
Separatory groove and the first inlet connect, and one end of described first inlet is connected with switching pipe, the other end of the first inlet and
Dustpan-shaped separatory groove connects, and one end of described dustpan-shaped separatory groove is connected with odd number connecting tube by funnel, dustpan-shaped separatory groove
The other end be connected with even number connecting tube by funnel；The side of described first inlet is provided with odd number sensor, the first feed liquor
The opposite side of mouth is provided with even number sensor；Described odd number sensor includes collecting tank, ball float, stay cord, odd-numbered switch, described ball float
Being positioned at collecting tank, described odd-numbered switch is for controlling the opening and closing of odd number connecting tube, and described ball float passes through stay cord and institute
State odd-numbered switch to connect；Described even number sensor includes that collecting tank, ball float, stay cord, even-numbered switch, described ball float are positioned at collecting tank
In, described even-numbered switch is for controlling the opening and closing of even number connecting tube, and described ball float is by stay cord and described even-numbered switch
Connect.
One multichannel injection valve of the present invention, wherein, the fluid apertures of described shell is connected with switching pipe；The odd row of described spool
Quantitative lumen pore connect and have odd number connecting tube, the quantitative lumen pore of even rows connects even number connecting tube, and described switching pipe is by cutting
Changing device switching and odd number connecting tube, the connection of even number connecting tube；Described switching device include with switching pipe be connected liquid-in pipe,
The left side being connected with odd number connecting tube goes out pipe and the right side being connected with even number connecting tube goes out pipe；Liquid-in pipe, a left side go out pipe and the right side goes out pipe and all hands over
It is compiled in base；Liquid-in pipe, a left side go out pipe and the right side goes out the outer wall of pipe and is all equidistantly laid with connector around axle center；Described connector includes
First rod, the second rod, the 3rd rod and the 4th rod；Described first rod radially extends from connecting tube outer wall；Described second rod axle
To setting, second rod the inner is perpendicularly fixed at the first rod top；4th rod radially inside extends from the second rod；Described base
Offer through hole；Through hole is equidistantly arranged around base axis；Base outer wall is arranged with water flowing ring；Water flowing ring and base enclose set out logical
Water cavity；Described water flowing ring covers through hole；Described water flowing chamber is by the inner space of through hole connection connector；Described water flowing ring connects
The right side is had to go out pipe；The described right side goes out pipe connection water flowing chamber；Base offers through hole；The right side goes out pipe and is connected to the through hole of base；Described base
Internal sleeve is provided with guiding piece；Described guiding piece includes guide sleeves, guided rings and guide ribs；Described guide sleeves is the cylinder of hollow
Body, guide sleeves one end is fixing connects guided rings, and the axial spaced set of outer wall of the other end has guide ribs；Described guide ribs inwall
It is fixed on guide sleeves, the inwall of outer wall laminating base；Described guide ribs two chamfer is arranged；Through hole is positioned at guide ribs and guided rings
Between；Base, guide sleeves and adjacent two guide ribs constitute a guidance cavity.
One multichannel injection valve difference from prior art of the present invention is that one multichannel injection valve of the present invention is by upper
State shell and drive valve core rotation, thus switch spool and different pipeline connections, in this manner it is possible to carry out sample introduction work and valve simultaneously
Cleaning, prepares for next group sample analysis, last consignment of sample analysis terminates just can carry out immediately next group sample introduction, with joint
Save analysis time.
Below in conjunction with the accompanying drawings a kind of multichannel injection valve of the present invention is described further.
Accompanying drawing explanation
Fig. 1 is the overall assembling design sketch of multichannel injection valve of the present invention；
Fig. 2 is the structural representation of the shell of multichannel injection valve of the present invention；
Fig. 3 is the structural representation of the spool of multichannel injection valve of the present invention；
Fig. 4 is the structural representation of the shell strap of multichannel injection valve of the present invention；
Fig. 5 is the structural representation of the motor of multichannel injection valve of the present invention；
Fig. 6 is the front view of the switching device of multichannel injection valve of the present invention；
Fig. 7 is the top view of another switching device of multichannel injection valve of the present invention.
Detailed description of the invention
Embodiment 1
As shown in Fig. 1～7, see Fig. 1,3, one multichannel injection valve of the present invention includes
Shell 132, its outer surface is provided with at least two outages 137, is internally provided with spool 127；And
Motor 129, its output shaft is fixed with described spool 127 by shaft coupling 130；
Wherein, described shell 132 is arranged on shaft coupling 130 by bearing, and described spool 127 is provided with at least two amounts of being ranked
Lumen pore, described spool 127 can switch the quantitative lumen pore of odd row, the quantitative lumen pore of even rows according to motor 129 rotation direction
Opening and closing.
The motor 129 of the present invention is rotated by above-mentioned shell 132 band movable valve plug 127, thus switches spool 127 and different pipes
Road connects, in this manner it is possible to carry out sample introduction work and valve cleaning simultaneously, prepares for next group sample analysis, last consignment of
Sample analysis terminates just can carry out next group sample introduction immediately, to save analysis time.
Wherein, the quantitative lumen pore of the odd row of spool 127 is that sample loads passage, the quantitative chamber of the odd row of spool 127
Two ends, hole connect with sample cell and waste-solution line respectively, and spool 127 carries out sample loading under the promotion of analysis Instrument equipment pump.
The quantitative lumen pore of the even rows of spool 127 is buffer or carrier fluid passage, the quantitative lumen pore of the even rows of spool 127
Two ends connect with the buffer of analytical tool or carrier fluid bottle/pond and high throughput testing device respectively.The main task of this state is
Quantitatively load testing sample, nor affect on i.e. this kind valve of collection of instrument detection signal simultaneously and can realize the continuous flowing of sample
Analyze；When it is in the i.e. sample analysis state of sample introduction duty, odd-numbered line lumen pore 101 on described spool 127,103,105,
107,109,111,113,115,117,119,121,123,125, be loaded with under previous state testing sample respectively with analysis
The buffer of instrument or carrier fluid bottle/pond and high throughput testing device UNICOM, even number line lumen pore 102,104,106,108,110,112,
114,116,118,120,122,124,126 be switched to respectively with pipeline-cleaning path and waste liquid path UNICOM, should be noted that
It is that sample introduction works and valve cleaning carries out i.e. system the most simultaneously and completes valve cleaning, for next while sample introduction works
Batch sample analysis is prepared, last consignment of sample analysis terminates just can carry out next group sample introduction immediately to save analysis time.
Preferably, described motor 129 is program control motor.
Preferably, the material of described spool 127 is macromolecule inert matrix material PEEK, PS or PDMS.
The material of spool 127 is preferably PPEK.
Preferably, described shell 132 makes material is macromolecule inert matrix material PEEK, PS and PDMS.
Shell 132 makes material and is preferably PDMS.
Preferably, the just surface to the quantitative lumen pore of spool 127 of described shell 132 is provided with shell strap 135, institute
State shell strap 135 and be provided with at least at least two outages 137.
Preferably, described shell strap 135 makes material is macromolecule inert matrix material PEEK, PS and PDMS.
Shell strap 135 makes material and is preferably macromolecule inert matrix material PEEK.
Preferably, on described spool 127, the number of rated capacity lumen pore is 2-1024.
The number of the quantitative lumen pore on spool 127 is preferably 96.
Preferably, seeing Fig. 6, the fluid apertures 137 of described shell 132 is connected with switching pipe 230；
The quantitative lumen pore of the odd row of described spool 127 connects odd number connecting tube 231, and the quantitative lumen pore of even rows connects
Having an even number connecting tube 232, described switching pipe 230 is by switching device switching and odd number connecting tube 231, even number connecting tube 232
Connecting, described switching device includes first extension fixture the 210, second extension fixture 220, described first extension fixture 210, second
The mutually symmetrical setting of extension fixture 220,
Described first extension fixture 210 includes the first housing 211, permanent magnet sleeve 212, guide pin bushing 213, push rod 214, electromagnetism
Ferrum sleeve 215, heading 216；
Described one end of first housing 211 is fixed with the inner surface of shell 132, is fixed with permanent magnet in the first housing 211
Sleeve 212, is set with at least two electric magnet sleeve 215, described at least two electric magnet sleeve in described permanent magnet sleeve 212
215 with permanent magnet sleeve 212 matched in clearance, the electric magnet sleeve 215 after described energising is suspended in permanent magnet set by magnetic induction
Cylinder 212 on and relative displacement can be produced；It is fixed with guide pin bushing 213, described guide pin bushing in described at least two electric magnet sleeve 215
One end away from opening of one end of 213 and the first housing 211 is by two orthogonal hinge, described guide pin bushing 213
Being made up of aluminum alloy materials, be provided with push rod 214 in described guide pin bushing 213, described push rod 214 has ferrous material to make, described push rod
214 are fixed with heading 216 near one end of the opening of the first housing 211, and described heading can be with the interior table of described expanding bar 204
Face contacts；
The heading 216 of described first extension fixture the 210, second extension fixture 220 connects with the two sides switching pipe 230 respectively
Touch, switching pipe 230 and shell 132 chain connection, described odd number connecting tube 231, even number connecting tube 232 with switching pipe 230 even
The one end connect is equipped with flaring connection bucket 233, and the length near another connection bucket 233 of said two connection bucket 233 is little
The length away from another connection bucket 233 in two connection buckets 233.
The present invention pass through said structure, can make switching pipe 230 switch over more flexibly in odd number, even number connecting tube it
Between, thus the switching between switching pipe 230 and connection bucket 233 is more flexible so that between switching pipe 230 and connection bucket 233
Switching times more, service life is longer, weares and teares less, and sealing effectiveness is more preferable.Wherein, non-magnetic guide pin bushing 213 and first
Housing 211, by two orthogonal hinge, can make guide pin bushing 213 can produce any side relative to the first housing 211
To twisting, meanwhile, the electric magnet sleeve 216 attracted each other, push rod 214 can be guided by guide pin bushing 213, thus to heading
216 guide.Electric magnet guide pin bushing 213 1 aspect is suspended on permanent magnet sleeve 212 by magnetic suspension effect, the most logical
Cross magnetic suspension effect and move in permanent magnet sleeve 212, thus drive push rod 214 to move, cause heading 216 driving switching pipe
230 switch between odd number, even number connecting tube flexibly along the guiding of hinge.Further, switching pipe 230 is by motor 129
Driving direction and while switching odd number, even number connecting tube, current switching also can be finely adjusted by switching device, so that cutting
Better tightness after changing.
Preferably, seeing Fig. 7, the fluid apertures 137 of described shell 132 is connected with switching pipe 230；The odd number of described spool 127
The quantitative lumen pore of row connects odd number connecting tube 231, and the quantitative lumen pore of even rows connects even number connecting tube 232, described switching
Pipe 230 is by switching device switching and odd number connecting tube 231, the connection of even number connecting tube 232；
Described switching device include fixing seat the 301, first inlet 302, odd number sensor 303, even number sensor 304,
Dustpan-shaped separatory groove 305；
Described fixing seat 301 is connected with described shaft coupling 130, and fixing seat 301 is entered with first by dustpan-shaped separatory groove 305
Liquid mouth 302 connects, one end of described first inlet 302 with switching pipe 230 be connected, the other end of the first inlet 302 with winnow with a dustpan
Dustpan shape separatory groove 305 connects, and one end of described dustpan-shaped separatory groove 305 is connected with odd number connecting tube 231 by funnel, dustpan-shaped
The other end of separatory groove 305 is connected with even number connecting tube 232 by funnel；
The side of described first inlet 302 is provided with odd number sensor 303, and the opposite side of the first inlet 302 is provided with idol
Number sensor 304；
Described odd number sensor 303 includes that collecting tank, ball float, stay cord, odd-numbered switch, described ball float are positioned at collecting tank,
Described odd-numbered switch is for controlling the opening and closing of odd number connecting tube 231, and described ball float is by stay cord and described odd-numbered switch
Connect；
Described even number sensor 304 includes that collecting tank, ball float, stay cord, even-numbered switch, described ball float are positioned at collecting tank,
Described even-numbered switch is for controlling the opening and closing of even number connecting tube 232, and described ball float is by stay cord and described even-numbered switch
Connect.
Fixing seat 301 angle change that the present invention can be caused according to the rotation of motor 129 by said structure is come
Carry out odd number or the feed liquor of the quantitative lumen pore of even number, in other words, its by the inclination of dustpan-shaped separatory groove 305 carry out odd number or
The feed liquor of the quantitative lumen pore of even number, and control odd number connecting tube, even number even by odd number sensor 303, even number sensor 304
The opening and closing of adapter, thus at the suitable angle of inclination of dustpan-shaped paging groove, carry out feed liquor order more accurately
Control.
Preferably, the fluid apertures 137 of described shell 132 is connected with switching pipe 230；The odd row of described spool 127 quantitative
Lumen pore connects odd number connecting tube 231, and the quantitative lumen pore of even rows connects has even number connecting tube 232, described switching pipe 230 to pass through
Switching device switching and odd number connecting tube 231, the connection of even number connecting tube 232；
Described switching device include the left side being connected with odd number connecting tube 231 with the switching liquid-in pipe that is connected of pipe 230 go out to manage and
The right side being connected with even number connecting tube 232 goes out pipe；Liquid-in pipe, a left side go out pipe and the right side goes out Guan Jun and is intersected in base；Liquid-in pipe, a left side go out pipe and
The right side goes out the outer wall of pipe and is all equidistantly laid with connector around axle center；Described connector includes the first rod, the second rod, the 3rd rod and
Four rods；Described first rod radially extends from connecting tube outer wall；Described second rod is axially arranged, and the second rod is inner vertical fixing
In the first rod top；4th rod radially inside extends from the second rod；Described base offers through hole；Through hole is around base axis
Equidistantly arrangement；Base outer wall is arranged with water flowing ring；Water flowing ring and base enclose and set out water flowing chamber；Described water flowing ring covers through hole；
Described water flowing chamber is by the inner space of through hole connection connector；Described water flowing ring connects has the right side to go out pipe；The described right side goes out pipe connection
Water flowing chamber；
Base offers through hole；The right side goes out pipe and is connected to the through hole of base；
Described base internal sleeve is provided with guiding piece；Described guiding piece includes guide sleeves, guided rings and guide ribs；Described guiding
Set is the cylinder of hollow, and guide sleeves one end is fixing connects guided rings, and the axial spaced set of outer wall of the other end has guide ribs；
Described guide ribs inwall is fixed on guide sleeves, the inwall of outer wall laminating base；Described guide ribs two chamfer is arranged；Through hole is positioned at
Between guide ribs and guided rings；Base, guide sleeves and adjacent two guide ribs constitute a guidance cavity.
The present invention can be realized by said structure and switch what the liquid-in pipe that pipe 230 is connected was connected with odd number connecting tube 231
A left side goes out pipe and the right side that is connected with even number connecting tube 232 goes out pipe and can optionally control its connected mode, i.e. according to the rotation of motor
And the angle of inclination of the pipeline caused, switch described switching pipe and odd number connecting tube 231, the connection of even number connecting tube 232.
Embodiment 2
Multichannel injection valve of the present invention includes that spool 127, the shell of shell 132 and described shell 132 phase sliding contact is fixed
Clamping plate 135 and drive spool 127 to move in circles the motor 129 slided, it is characterised in that: described shell 132 and shell are solid
There is on clamp plate 135 fluid apertures 137 being connected with sample pump and high throughput analysis device detector and waste liquid pool pipeline, valve
Built-in quantitative function on core 127 is sliding by shaft coupling 130 and power transmission shaft 131 push-and-pull by motor when described spool 127 slides
Dynamic, with switched path.
Described injection valve has sampling duty, sample introduction duty and valve cleaning state, when it is in sampling
During duty, odd-numbered line lumen pore 101 on described spool 127,103,105,107,109,111,113,115,117,119,
121,123,125 load passage as sample, join with the sample cell on shell 132 and fixing shell 135 and waste liquid path respectively
Logical, under the promotion of analysis Instrument equipment pump, carry out sample loading, meanwhile, even number line lumen pore 102 on spool 127,104,
106,108,110,112,114,116,118,120,122,124,126 as buffer or carrier fluid passage, respectively with analyser
The buffer of device or carrier fluid bottle/pond and high throughput testing device UNICOM, the main task of this state be quantitatively load testing sample,
I.e. this kind valve of collection simultaneously nor affecting on instrument detection signal can realize the Continuous Flow Analysis of sample；When it is in sample introduction work
When making the i.e. sample analysis state of state, odd-numbered line lumen pore 101 on described spool 127,103,105,107,109,111,113,
115,117,119,121,123,125, be loaded with under previous state testing sample respectively with buffer or the load of analytical tool
Liquid bottle/pond and high throughput testing device UNICOM, even number line lumen pore 102,104,106,108,110,112,114,116,118,120,
122,124,126 be switched to respectively with pipeline-cleaning path and waste liquid path UNICOM, it should be noted that sample introduction work and valve are clear
Clean work carries out i.e. system the most simultaneously and completes valve cleaning while sample introduction works, and does standard for next group sample analysis
Standby, last consignment of sample analysis terminates just can carry out next group sample introduction immediately to save analysis time.
The quantitative lumen pore preferred 1mm of a diameter of 0.5-3mm on described spool 127, determined volume are that 5-500ul is preferred
100ul。
Described motor is commercially available common program control motor.
It is the one in macromolecule inert matrix material PEEK, PS and PDMS that described spool 127 makes material, preferably
PPEK。
It is the one in macromolecule inert matrix material PEEK, PS and PDMS that described shell 132 makes material, preferably
PDMS。
It is in macromolecule inert matrix material PEEK, PS and PDMS that described shell strap 135 makes material
Kind, preferably PEEK.
On described spool 127, quantitative lumen pore is 2-1024 path, preferably 96 paths.
Referring to Fig. 1-5, the multichannel injection valve assembly work of the present invention follows principle the most from top to bottom with side
Just practical operation, concrete operation method is:
The most first by spool 127 as shown in Figure 3 by motor coupler 130 motor transmission shaft 131 with motor 129 the most even
Receive together, form valve body slides parts；
S200. shell strap 135 the latter half is fixed on injection valve mounting platform, then by injection valve shell
Shell strap 135 is inserted by the hole, location of shell strap 135 in 132 the latter half, assembles the valve body obtained by 1 sliding
Dynamic component is loaded shell 132 by the spacing hole on shell 132, motor 129 is fixed to injection valve mounting platform simultaneously；
S300. injection valve shell 132 top half is anchored to spool 127 top half by position-limit mechanism, then outward
Shell strap 135 top half is anchored to shell 132 top half by position-limit mechanism, is fixed by shell with threaded spindle cap nut simultaneously
Clamping plate about 135 two parts are fixing tightly, attention can not affect the spool spool 127 driving lower slider at motor 129, extremely after fixing
This present invention multichannel injection valve assembling complete, remaining as the work such as connecting line can according to reality apply and analytical tool platform
From main modulation.
The present invention uses multichannel injection valve once 96 samples to be accurately injected into 96 hole ELISA Plate.
The multichannel injection valve present invention prepared is applied to detect the operational approach of content of melamine in milk, specifically walks
Rapid as follows:
The multichannel injection valve assembled from embodiment 3 chooses 96 paths for being noted by 96 testing samples the most simultaneously
Enter to 96 hole ELISA Plate, be embodied as step as follows:
Testing sample is that (PBS prepares clenobuterol hydrochloride solution, and concentration is respectively 0.5ng/ml, 1ng/ml, 1.5ng/
Ml, 2.0ng/ml, 3.0ng/ml), clenobuterol hydrochloride Elisa detection kit (Shenzhen security personnel's limited public affairs of health biotechnology
Department), capital equipment have microplate reader (Thermo Labsystems Multiskan MK3), all size Eppendorf move liquid
Rifle (10ul, 20ul, 200ul, 1000ul, 300ul volley of rifle fire), 96 hole ELISA Plate:
1. sample pre-treatments and the operation of sample detection methods reference reagent box shop instruction.
2. the sample (500ul) that pre-treatment is good proceeds to 96 hole ELISA Plate, puts into aforementioned by the sampling probe of injection valve front end
96 hole ELISA Plate of 500ul sample (noticing that sampling needle point is all the time below liquid level), open pump and control software design patterns parameter (sample introduction
Amount 50ul, sample introduction flow velocity 200ul/ml) it is sampled operation, control software by absorption again by injection valve after sampling
Sample joins another block and is coated with the ELISA Plate of clenobuterol hydrochloride antigen, and subsequent step reference reagent box description operates,
Injection valve sampling probe is put in cleanout fluid after completing after cleaning dries up and prepares to sample next time by sample feeding.
3. control experiment: the sample of control experiment is drawn and operated fully according to Elisa kit method.
Experimental result is as shown in table 1, whether can produce cross-contamination to test, enters in experiment between each passage of injection valve
Specially low concentration and enriched sample are randomly placed in 96 hole ELISA Plate during sample, do not hand between result display each sample
Fork pollutes, between big volume low-concentration (0.5ng/ml) is in high concentration (3ng/ml) sample test batch and batch in difference respectively less than
10%, illustrate that the multichannel injection valve that the present invention provides can be fully integrated into full-automatic microplate reader, washes trigger and full-automatic chemical
To save sample analysis time, to improve equipment work efficiency in the detecting systems such as luminescence immunoassay instrument.
Table 1 below is embodiment 2 experimental result
Chart is numbered: in C0, testing sample, clenobuterol hydrochloride adds concentration (ng/ml)；Hydrochloric acid in C, actual measurement sample
Clenbuterol concentration (ng/ml).
Table 1
Embodiment described above is only to be described the preferred embodiment of the present invention, the not model to the present invention
Enclose and be defined, on the premise of designing spirit without departing from the present invention, the those of ordinary skill in the art technical side to the present invention
Various deformation that case is made and improvement, all should fall in the protection domain that claims of the present invention determines.
Claims (10)
1. a multichannel injection valve, it is characterised in that: include
Shell (132), its outer surface is provided with at least two outages (137), is internally provided with spool (127)；And
Motor (129), its output shaft is fixed with described spool (127) by shaft coupling (130)；
Wherein, described shell (132) is arranged on shaft coupling (130) by bearing, and described spool (127) is provided with at least two and is ranked
Amount lumen pore, described spool (127) can be according to motor (129) the rotation direction switching quantitative lumen pore of odd row, the determining of even rows
The opening and closing of amount lumen pore.
A kind of multichannel injection valve the most according to claim 1, it is characterised in that: described motor (129) is program control motor.
A kind of multichannel injection valve the most according to claim 1, it is characterised in that: the material of described spool (127) is high score
Sub-inert matrix material PEEK, PS or PDMS.
A kind of multichannel injection valve the most according to claim 1, it is characterised in that: it is high that described shell (132) makes material
Molecule inert matrix material PEEK, PS and PDMS.
A kind of multichannel injection valve the most according to claim 1, it is characterised in that: described shell (132) just to spool
(127) surface of quantitative lumen pore is provided with shell strap (135), and described shell strap (135) is provided with the most extremely
Few two outages (137).
A kind of multichannel injection valve the most according to claim 5, it is characterised in that: described shell strap (135) makes
Material is macromolecule inert matrix material PEEK, PS and PDMS.
A kind of multichannel injection valve the most according to claim 1, it is characterised in that: the upper rated capacity lumen pore of described spool (127)
Number be 2-1024.
A kind of multichannel injection valve the most according to claim 1, it is characterised in that: the fluid apertures (137) of described shell (132) with
Switching pipe (230) connects；
The quantitative lumen pore of the odd row of described spool (127) connects odd number connecting tube (231), and the quantitative lumen pore of even rows connects
Having even number connecting tube (232), described switching pipe (230) is by switching device switching and odd number connecting tube (231), even number connecting tube
(232) connection, described switching device includes the first extension fixture (210), the second extension fixture (220), described first expansion
Device (210), the second extension fixture (220) mutually symmetrical setting,
Described first extension fixture (210) includes the first housing (211), permanent magnet sleeve (212), guide pin bushing (213), push rod
(214), electric magnet sleeve (215), heading (216)；
One end of described first housing (211) is fixed with the inner surface of shell (132), and the first housing is fixed with permanent magnetism in (211)
Ferrum sleeve (212), is set with at least two electric magnet sleeve (215), described at least two electricity in described permanent magnet sleeve (212)
Magnet sleeve (215) and permanent magnet sleeve (212) matched in clearance, the electric magnet sleeve (215) after described energising passes through magnetic induction
It is suspended in permanent magnet sleeve (212) and above and relative displacement can be produced；It is fixed with in described at least two electric magnet sleeve (215)
Guide pin bushing (213), one end of described guide pin bushing (213) is mutually perpendicular to by two with one end away from opening of the first housing (211)
Hinge, described guide pin bushing (213) is made up of aluminum alloy materials, is provided with push rod (214), described top in described guide pin bushing (213)
Bar (214) has ferrous material to make, and described push rod (214) is fixed with heading near one end of the opening of the first housing (211)
(216), described heading can contact with the inner surface of described expanding bar (204)；
Described first extension fixture (210), the heading (216) of the second extension fixture (220) manage the two sides of (230) with switching respectively
Contact, switching pipe (230) and shell (132) chain connection, described odd number connecting tube (231), even number connecting tube (232) with cut
Change one end that pipe (230) connects and be equipped with flaring connection bucket (233), said two connection bucket (233) near another even
Connect the length length away from another connection bucket (233) less than two connection buckets (233) of bucket (233).
A kind of multichannel injection valve the most according to claim 1, it is characterised in that: the fluid apertures (137) of described shell (132) with
Switching pipe (230) connects；The quantitative lumen pore of the odd row of described spool (127) connects odd number connecting tube (231), even rows
Quantitatively lumen pore connects even number connecting tube (232), and described switching pipe (230) is by switching device switching and odd number connecting tube
(231), the connection of even number connecting tube (232)；
Described switching device includes fixing seat (301), the first inlet (302), odd number sensor (303), even number sensor
(304), dustpan-shaped separatory groove (305)；
Described fixing seat (301) is connected with described shaft coupling (130), and fixing seat (301) is by dustpan-shaped separatory groove (305) and the
One inlet (302) connects, and one end of described first inlet (302) is connected with switching pipe (230), the first inlet (302)
The other end be connected with dustpan-shaped separatory groove (305), one end of described dustpan-shaped separatory groove (305) is connected with odd number by funnel
Pipe (231) connects, and the other end of dustpan-shaped separatory groove (305) is connected with even number connecting tube (232) by funnel；
The side of described first inlet (302) is provided with odd number sensor (303), and the opposite side of the first inlet (302) is provided with
Even number sensor (304)；
Described odd number sensor (303) includes that collecting tank, ball float, stay cord, odd-numbered switch, described ball float are positioned at collecting tank, institute
Stating odd-numbered switch for controlling the opening and closing of odd number connecting tube (231), described ball float is by stay cord and described odd-numbered switch
Connect；
Described even number sensor (304) includes that collecting tank, ball float, stay cord, even-numbered switch, described ball float are positioned at collecting tank, institute
Stating even-numbered switch for controlling the opening and closing of even number connecting tube (232), described ball float is by stay cord and described even-numbered switch
Connect.
A kind of multichannel injection valve the most according to claim 1, it is characterised in that: the fluid apertures (137) of described shell (132)
It is connected with switching pipe (230)；The quantitative lumen pore of the odd row of described spool (127) connects odd number connecting tube (231), even rows
Quantitative lumen pore connect and have an even number connecting tube (232), described switching pipe (230) is by switching device switching and odd number connecting tube
(231), the connection of even number connecting tube (232)；
Described switching device include the left side being connected with odd number connecting tube (231) with switching pipe (230) liquid-in pipe that is connected go out pipe and
The right side being connected with even number connecting tube (232) goes out pipe；Liquid-in pipe, a left side go out pipe and the right side goes out Guan Jun and is intersected in base；Liquid-in pipe, a left side go out pipe
The outer wall going out pipe with the right side is all equidistantly laid with connector around axle center；Described connector include the first rod, the second rod, the 3rd rod and
4th rod；Described first rod radially extends from connecting tube outer wall；Described second rod is axially arranged, and the second rod is inner vertical solid
Due to the first rod top；4th rod radially inside extends from the second rod；Described base offers through hole；Through hole is in base
Axle is equidistantly arranged；Base outer wall is arranged with water flowing ring；Water flowing ring and base enclose and set out water flowing chamber；Described water flowing ring covers logical
Hole；Described water flowing chamber is by the inner space of through hole connection connector；Described water flowing ring connects has the right side to go out pipe；The described right side goes out Guan Lian
Water cavity all；
Base offers through hole；The right side goes out pipe and is connected to the through hole of base；
Described base internal sleeve is provided with guiding piece；Described guiding piece includes guide sleeves, guided rings and guide ribs；Described guide sleeves is
The cylinder of hollow, guide sleeves one end is fixing connects guided rings, and the axial spaced set of outer wall of the other end has guide ribs；Described
Guide ribs inwall is fixed on guide sleeves, the inwall of outer wall laminating base；Described guide ribs two chamfer is arranged；Through hole is positioned at guiding
Between bar and guided rings；Base, guide sleeves and adjacent two guide ribs constitute a guidance cavity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610587541.8A CN106195331B (en) | 2016-07-22 | 2016-07-22 | A kind of multichannel sampling valve |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610587541.8A CN106195331B (en) | 2016-07-22 | 2016-07-22 | A kind of multichannel sampling valve |
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| CN106195331A true CN106195331A (en) | 2016-12-07 |
| CN106195331B CN106195331B (en) | 2019-04-26 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109374798A (en) * | 2018-10-16 | 2019-02-22 | 安徽皖仪科技股份有限公司 | Multi-tube composite sampling valve and its application method |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012067833A (en) * | 2010-09-22 | 2012-04-05 | Fuji Koki Corp | Multi-way selector valve |
| JP2013195370A (en) * | 2012-03-22 | 2013-09-30 | Saitama Univ | Liquid dividing method and liquid dividing kit |
| CN103574129A (en) * | 2012-07-20 | 2014-02-12 | 通用汽车环球科技运作有限责任公司 | Electronically controlled valve assembly |
| CN104373630A (en) * | 2013-08-17 | 2015-02-25 | 宋久林 | Rotary proportional reversing valve |
| CN105402441A (en) * | 2014-09-10 | 2016-03-16 | 株式会社丰田自动织机 | Rotary valve device |
-
2016
- 2016-07-22 CN CN201610587541.8A patent/CN106195331B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012067833A (en) * | 2010-09-22 | 2012-04-05 | Fuji Koki Corp | Multi-way selector valve |
| JP2013195370A (en) * | 2012-03-22 | 2013-09-30 | Saitama Univ | Liquid dividing method and liquid dividing kit |
| CN103574129A (en) * | 2012-07-20 | 2014-02-12 | 通用汽车环球科技运作有限责任公司 | Electronically controlled valve assembly |
| CN104373630A (en) * | 2013-08-17 | 2015-02-25 | 宋久林 | Rotary proportional reversing valve |
| CN105402441A (en) * | 2014-09-10 | 2016-03-16 | 株式会社丰田自动织机 | Rotary valve device |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109374798A (en) * | 2018-10-16 | 2019-02-22 | 安徽皖仪科技股份有限公司 | Multi-tube composite sampling valve and its application method |
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| CN106195331B (en) | 2019-04-26 |
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