CN106195331B - A kind of multichannel sampling valve - Google Patents
A kind of multichannel sampling valve Download PDFInfo
- Publication number
- CN106195331B CN106195331B CN201610587541.8A CN201610587541A CN106195331B CN 106195331 B CN106195331 B CN 106195331B CN 201610587541 A CN201610587541 A CN 201610587541A CN 106195331 B CN106195331 B CN 106195331B
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- China
- Prior art keywords
- shell
- connecting tube
- spool
- pipe
- connection
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Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K11/00—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves
- F16K11/02—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit
- F16K11/06—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements
- F16K11/065—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements with linearly sliding closure members
- F16K11/0655—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements with linearly sliding closure members with flat slides
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K19/00—Arrangements of valves and flow lines specially adapted for mixing fluids
- F16K19/006—Specially adapted for faucets
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K27/00—Construction of housing; Use of materials therefor
- F16K27/04—Construction of housing; Use of materials therefor of sliding valves
- F16K27/044—Construction of housing; Use of materials therefor of sliding valves slide valves with flat obturating members
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K3/00—Gate valves or sliding valves, i.e. cut-off apparatus with closing members having a sliding movement along the seat for opening and closing
- F16K3/30—Details
- F16K3/314—Forms or constructions of slides; Attachment of the slide to the spindle
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K31/00—Actuating devices; Operating means; Releasing devices
- F16K31/02—Actuating devices; Operating means; Releasing devices electric; magnetic
- F16K31/04—Actuating devices; Operating means; Releasing devices electric; magnetic using a motor
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L39/00—Joints or fittings for double-walled or multi-channel pipes or pipe assemblies
- F16L39/04—Joints or fittings for double-walled or multi-channel pipes or pipe assemblies allowing adjustment or movement
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
- G01N35/085—Flow Injection Analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Multiple-Way Valves (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
A kind of multichannel sampling valve of the present invention includes shell (132), and outer surface is equipped at least two drainage holes (137), is internally provided with spool (127)；And motor (129), output shaft are fixed by shaft coupling (130) and the spool (127)；Wherein, the shell (132) is mounted on shaft coupling (130) by bearing, the spool (127) is equipped at least two rows of quantitative lumen pores, and the spool (127) can switch the opening and closing of the quantitative lumen pore of odd row, the quantitative lumen pore of even rows according to motor (129) rotation direction.Shell and relative rotor displacement is smaller, multiple continuous sample introduction residual contamination is small when the invention works, it is quantitative accurate, functional, it is low in cost.
Description
Technical field
The present invention relates to a kind of components of analysis instrument, more particularly to a kind of valve.
Background technique
Flow Injection Analysis refers to using spectrophotometer, fluophotometer, the atomic absorption spectrophotometry light that flow cell is housed
The detectors analysis measurement such as degree meter and ionometer has the capacity (sample of the reagent flow (sample to be tested is included in reagent flow) of flow velocity
Product content) method, i.e., replace beaker and volumetric flask with polyfluortetraethylene pipe or PEEK pipe, analyzed by flow injection
Method.Having an important link in Flow Injection Analysis System is exactly accurately by sample to be tested Injection Detector.Traditional
Way is that sample is injected analysis system by six-way valve (such as classical 7725i six-way valves), but (high pass with advances in technology
The appearance of amount detector) and actual demand growth, especially often needed in Flow injection immunoassay system, in production practices
Hundreds and thousands of a samples are simultaneously accurately injected into high throughput analysis systems, six-way valve used in parallel will generate extremely complex
Liquid line, the motor driven systems of huge number and high cost, this causes many difficulties to practical application.
Summary of the invention
That the technical problem to be solved in the present invention is to provide a kind of structures is simple, at low cost, easily to operate a kind of multichannel into
Sample valve.
A kind of multichannel sampling valve of the present invention, including shell, outer surface are equipped at least two drainage holes, are internally provided with valve
Core；And motor, output shaft are fixed by shaft coupling and the spool；Wherein, the shell is mounted on shaft coupling by bearing
On, the spool is equipped at least two rows of quantitative lumen pores, and the spool can switch quantifying for odd row according to direction of motor rotation
Lumen pore, even rows quantitative lumen pore opening and closing.
A kind of multichannel sampling valve of the present invention, wherein the motor is program-controlled motor.
A kind of multichannel sampling valve of the present invention, wherein the material of the spool be macromolecule inert matrix material PEEK, PS or
PDMS。
A kind of multichannel sampling valve of the present invention, wherein the shell making material is macromolecule inert matrix material PEEK, PS
And PDMS.
A kind of multichannel sampling valve of the present invention, wherein the surface of the quantitative lumen pore of the face spool of the shell is equipped with shell
Strap, the shell strap are equipped at least two drainage holes.
A kind of multichannel sampling valve of the present invention, wherein the shell strap making material is macromolecule inertia composite wood
Expect PEEK, PS and PDMS.
A kind of multichannel sampling valve of the present invention, wherein the number of the quantitative lumen pore on the spool is-it is a.
A kind of multichannel sampling valve of the present invention, wherein the fluid apertures of the shell is connect with switching pipe；The odd row of the spool
Quantitative lumen pore be connected with odd number connecting tube, the quantitative lumen pore of even rows is connected with even number connecting tube, and the switching pipe is by cutting
The connection of changing device switching and odd number connecting tube, even number connecting tube, the switching device include the first extension fixture, the second expansion
Device, first extension fixture, the mutually symmetrical setting of the second extension fixture, first extension fixture include first shell,
Permanent magnet sleeve, guide sleeve, mandril, electromagnet sleeve, heading；One end of the first shell and the inner surface of shell are fixed, the
It is fixed with permanent magnet sleeve in one shell, is set at least two electromagnet sleeves in the permanent magnet sleeve, described at least two
A electromagnet sleeve and permanent magnet sleeve clearance fit, the electromagnet sleeve after the energization are suspended in permanent magnet by magnetic induction
On sleeve and relative displacement can be generated；Be fixed with guide sleeve in at least two electromagnet sleeve, one end of the guide sleeve with
One end of the separate opening of first shell is hinged by two orthogonal hinges, and the guide sleeve is made of aluminum alloy materials,
Mandril is equipped in the guide sleeve, the mandril is made of ferrous material, and the mandril is solid close to one end of the opening of first shell
Surely there is heading, the heading can be contacted with the inner surface of the mandril；The top of first extension fixture, the second extension fixture
Ball respectively with switching pipe two face contacts, switching pipe connect with shell hinge, the odd number connecting tube, even number connecting tube with cut
The one end for changing pipe connection is equipped with tubaeform connection bucket, and the length close to another connection bucket of described two connection buckets is less than two
The length far from another connection bucket of a connection bucket.
A kind of multichannel sampling valve of the present invention, wherein the fluid apertures of the shell is connect with switching pipe；The odd row of the spool
Quantitative lumen pore be connected with odd number connecting tube, the quantitative lumen pore of even rows is connected with even number connecting tube, and the switching pipe is by cutting
The connection of changing device switching and odd number connecting tube, even number connecting tube；The switching device includes fixing seat, the first inlet, surprise
Number sensor, even number sensor, dustpan-shaped liquid separation slot；The fixing seat is connect with the shaft coupling, and fixing seat passes through dustpan-shaped
Liquid separation slot is connect with the first inlet, and one end of first inlet connect with switching pipe, the other end of the first inlet and
Dustpan-shaped liquid separation slot connection, one end of the dustpan-shaped liquid separation slot are connect by funnel with odd number connecting tube, dustpan-shaped liquid separation slot
The other end connect with even number connecting tube by funnel；The side of first inlet is equipped with odd number sensor, the first feed liquor
The other side of mouth is equipped with even number sensor；The odd number sensor includes collecting tank, floating ball, drawstring, odd-numbered switch, the floating ball
In collecting tank, the odd-numbered switch is used to control the opening and closing of odd number connecting tube, and the floating ball passes through drawstring and institute
State odd-numbered switch connection；The even number sensor includes collecting tank, floating ball, drawstring, even-numbered switch, and the floating ball is located at collecting tank
Interior, the even-numbered switch is used to control the opening and closing of even number connecting tube, and the floating ball passes through drawstring and the even-numbered switch
Connection.
A kind of multichannel sampling valve of the present invention, wherein the fluid apertures of the shell is connect with switching pipe；The odd row of the spool
Quantitative lumen pore be connected with odd number connecting tube, the quantitative lumen pore of even rows is connected with even number connecting tube, and the switching pipe is by cutting
The connection of changing device switching and odd number connecting tube, even number connecting tube；The switching device include with switching pipe connect liquid-in pipe,
The left outlet pipe being connect with odd number connecting tube and the right outlet pipe being connect with even number connecting tube；Liquid-in pipe, left outlet pipe and right outlet pipe are handed over
It is compiled in tube socket；The outer wall of liquid-in pipe, left outlet pipe and right outlet pipe is equidistantly laid with connector around axle center；The connector includes
First rod, the second rod, third rod and the 4th rod；First rod is radially extended from connection pipe outer wall；The second rod axis
To setting, the second rod inner end is perpendicularly fixed at the top of the first rod；4th rod radially inside extends from the second rod；The tube socket
Offer through-hole；Through-hole is equidistantly arranged around tube socket axis；Tube socket outer wall is arranged with water flowing ring；Water flowing ring and tube socket enclose set out it is logical
Water cavity；The water flowing ring covers through-hole；The water flowing chamber is connected to the inner space of connector by through-hole；The water flowing ring connection
There is right outlet pipe；The right outlet pipe is connected to water flowing chamber；Tube socket offers through-hole；Right outlet pipe is connected to the through-hole of tube socket；The tube socket
Internal sleeve is equipped with guiding piece；The guiding piece includes guide sleeves, guided rings and guide ribs；The guide sleeves are hollow cylinder
Body, guide sleeves one end are fixedly connected with guided rings, and the outer wall axial direction spaced set of the other end has guide ribs；The guide ribs inner wall
Guide sleeves are fixed on, outer wall is bonded the inner wall of tube socket；Two end chamfer of the guide ribs setting；Through-hole is located at guide ribs and guided rings
Between；Tube socket, guide sleeves and two adjacent guide ribs constitute a guidance cavity.
It is upper that a kind of multichannel sampling valve difference from prior art of the present invention is that a kind of multichannel sampling valve of the present invention passes through
It states shell and drives valve core rotation, to switch spool and different pipeline connections, in this manner it is possible to carry out sample introduction work and valve simultaneously
Cleaning, for next group sample analysis is prepared, last consignment of sample analysis terminates that next group sample introduction can be carried out immediately, with section
Save analysis time.
A kind of multichannel sampling valve of the invention is described further with reference to the accompanying drawing.
Detailed description of the invention
Fig. 1 is the whole assembly effect picture of multichannel sampling valve of the present invention；
Fig. 2 is the structural schematic diagram of the shell of multichannel sampling valve of the present invention；
Fig. 3 is the structural schematic diagram of the spool of multichannel sampling valve of the present invention；
Fig. 4 is the structural schematic diagram of the shell strap of multichannel sampling valve of the present invention；
Fig. 5 is the structural schematic diagram of the motor of multichannel sampling valve of the present invention；
Fig. 6 is the main view of the switching device of multichannel sampling valve of the present invention；
Fig. 7 is the top view of another switching device of multichannel sampling valve of the present invention.
Specific embodiment
Embodiment 1
As shown in Fig. 1~7, referring to Fig. 1,3, a kind of multichannel sampling valve of the present invention includes
Shell 132, outer surface are equipped at least two drainage holes 137, are internally provided with spool 127；And
Motor 129, output shaft are fixed by shaft coupling 130 and the spool 127；
Wherein, the shell 132 is mounted on shaft coupling 130 by bearing, and the spool 127 is equipped at least two rows of quantitative
Lumen pore, the spool 127 can switch the quantitative lumen pore of odd row, the quantitative lumen pore of even rows according to 129 rotation direction of motor
Opening and closing.
Motor 129 of the invention is rotated by above-mentioned shell 132 with movable valve plug 127, to switch spool 127 and different pipes
Road connection is prepared, last consignment of in this manner it is possible to carry out sample introduction work and valve cleaning simultaneously for next group sample analysis
Sample analysis terminates that next group sample introduction can be carried out immediately, to save analysis time.
Wherein, the quantitative lumen pore of the odd row of spool 127 is that sample loads channel, the quantitative chamber of the odd row of spool 127
Hole both ends are connected to sample cell and waste-solution line respectively, and spool 127 carries out sample load under the promotion that analysis Instrument equipment pumps.
The quantitative lumen pore of the even rows of spool 127 is buffer or carrier fluid channel, the quantitative lumen pore of the even rows of spool 127
Both ends are connected to the buffer of analysis instrument or carrier fluid bottle/pond and high pass amount detector respectively.The main task of this state is
It quantitatively loads sample to be tested while the continuous flowing of sample may be implemented in i.e. this kind of valve of acquisition for nor affecting on instrument detection signal
Analysis；When it is in sample introduction working condition, that is, sample analysis state, odd-numbered line lumen pore 101 on the spool 127,103,105,
107,109,111,113,115,117,119,121,123,125, be loaded under previous state sample to be tested respectively with analysis
Buffer or carrier fluid bottle/pond of instrument and high pass amount detector connection, even number line lumen pore 102,104,106,108,110,112,
114,116,118,120,122,124,126 be switched to respectively with pipeline-cleaning access and waste liquid access connection, it should be noted that
It is sample introduction work and valve cleaning almost while carries out i.e. system completion valve cleaning while sample introduction work, is next
Batch sample analysis is prepared, last consignment of sample analysis terminates to carry out next group sample introduction immediately to save analysis time.
Preferably, the motor 129 is program-controlled motor.
Preferably, the material of the spool 127 is macromolecule inert matrix material PEEK, PS or PDMS.
The material of spool 127 is preferably PPEK.
Preferably, 132 making material of shell is macromolecule inert matrix material PEEK, PS and PDMS.
132 making material of shell is preferably PDMS.
Preferably, the surface of the quantitative lumen pore of the face spool 127 of the shell 132 is equipped with shell strap 135, institute
Shell strap 135 is stated equipped at least two drainage holes 137.
Preferably, 135 making material of shell strap is macromolecule inert matrix material PEEK, PS and PDMS.
135 making material of shell strap is preferably macromolecule inert matrix material PEEK.
Preferably, the number of the quantitative lumen pore on the spool 127 is 2-1024.
The number of quantitative lumen pore on spool 127 is preferably 96.
Preferably, referring to Fig. 6, the fluid apertures 137 of the shell 132 is connect with switching pipe 230；
The quantitative lumen pore of the odd row of the spool 127 is connected with odd number connecting tube 231, the quantitative lumen pore connection of even rows
There is an even number connecting tube 232, the switching pipe 230 switches by switching device and odd number connecting tube 231, even number connecting tube 232
Connection, the switching device include the first extension fixture 210, the second extension fixture 220, first extension fixture 210, second
The mutually symmetrical setting of extension fixture 220,
First extension fixture 210 includes first shell 211, permanent magnet sleeve 212, guide sleeve 213, mandril 214, electromagnetism
Iron sleeve 215, heading 216；
One end of the first shell 211 and the inner surface of shell 132 are fixed, and are fixed with permanent magnet in first shell 211
Sleeve 212 is set at least two electromagnet sleeves 215, at least two electromagnet sleeve in the permanent magnet sleeve 212
215 with 212 clearance fit of permanent magnet sleeve, and the electromagnet sleeve 215 after the energization is suspended in permanent magnet set by magnetic induction
On cylinder 212 and relative displacement can be generated；Guide sleeve 213, the guide sleeve are fixed in at least two electromagnet sleeve 215
One end of 213 one end and the separate opening of first shell 211 is hinged by two orthogonal hinges, the guide sleeve 213
It is made of aluminum alloy materials, is equipped with mandril 214 in the guide sleeve 213, the mandril 214 is made of ferrous material, the mandril
214 are fixed with heading 216 close to one end of the opening of first shell 211, and the heading can be contacted with the inner surface of mandril；
Two sides of the heading 216 of first extension fixture 210, the second extension fixture 220 respectively with switching pipe 230 connects
Touching, switching pipe 230 connect with 132 hinge of shell, the odd number connecting tube 231, even number connecting tube 232 with switch pipe 230 company
The one end connect is equipped with tubaeform connection bucket 233, and the length close to another connection bucket 233 of described two connection buckets 233 is small
In the length far from another connection bucket 233 of two connection buckets 233.
The present invention by above structure, can make to switch pipe 230 more flexibly switch in odd number, even number connecting tube it
Between, so that the switching between switching pipe 230 and connection bucket 233 is more flexible, so that between switching pipe 230 and connection bucket 233
Switching times it is more, the service life is longer, wear it is smaller, sealing effect is more preferable.Wherein, non-magnetic guide sleeve 213 and first
Shell 211 is hinged by two orthogonal hinges, and guide sleeve 213 can be enable to generate any side relative to first shell 211
To twisting, meanwhile, guide sleeve 213 can be oriented to electromagnet sleeve 215, the mandril 214 to attract each other, thus to heading
216 are oriented to.213 one side of electromagnet guide sleeve is suspended on permanent magnet sleeve 212 by magnetic levitation effect, on the other hand logical
It crosses magnetic levitation effect and is moved in permanent magnet sleeve 212, to drive mandril 214 mobile, cause 216 driving switching pipe of heading
230 along hinge guiding and flexibly switch between odd number, even number connecting tube.Also, switch pipe 230 by motor 129
Driving direction and while switch odd number, even number connecting tube, switching device can also be finely adjusted current switching, to make to cut
Better tightness after changing.
Preferably, referring to Fig. 7, the fluid apertures 137 of the shell 132 is connect with switching pipe 230；The odd number of the spool 127
The quantitative lumen pore of row is connected with odd number connecting tube 231, and the quantitative lumen pore of even rows is connected with even number connecting tube 232, the switching
The connection that pipe 230 passes through switching device switching and odd number connecting tube 231, even number connecting tube 232；
The switching device include fixing seat 301, the first inlet 302, odd number sensor 303, even number sensor 304,
Dustpan-shaped liquid separation slot 305；
The fixing seat 301 is connect with the shaft coupling 130, fixing seat 301 by dustpan-shaped liquid separation slot 305 and first into
Liquid mouth 302 connects, and one end of first inlet 302 is connect with pipe 230 is switched, the other end of the first inlet 302 with winnow with a dustpan
Dustpan shape liquid separation slot 305 connects, and one end of the dustpan-shaped liquid separation slot 305 is connect by funnel with odd number connecting tube 231, dustpan-shaped
The other end of liquid separation slot 305 is connect by funnel with even number connecting tube 232；
The side of first inlet 302 is equipped with odd number sensor 303, and the other side of the first inlet 302 is equipped with even
Number sensor 304；
The odd number sensor 303 includes collecting tank, floating ball, drawstring, odd-numbered switch, and the floating ball is located in collecting tank,
The odd-numbered switch is used to control the opening and closing of odd number connecting tube 231, and the floating ball passes through drawstring and the odd-numbered switch
Connection；
The even number sensor 304 includes collecting tank, floating ball, drawstring, even-numbered switch, and the floating ball is located in collecting tank,
The even-numbered switch is used to control the opening and closing of even number connecting tube 232, and the floating ball passes through drawstring and the even-numbered switch
Connection.
The present invention by above structure can according to 301 angle change of fixing seat caused by the rotation of motor 129 come
Carry out the feed liquor that odd number or even number quantify lumen pore, in other words, carried out by the inclination of dustpan-shaped liquid separation slot 305 odd number or
Even number quantifies the feed liquor of lumen pore, and odd number connecting tube, even number company are controlled by odd number sensor 303, even number sensor 304
The opening and closing of adapter tube carry out feed liquor sequence more accurately thus in the tilt angle appropriate of dustpan-shaped liquid separation slot
Control.
Preferably, the fluid apertures 137 of the shell 132 is connect with switching pipe 230；The odd row of the spool 127 quantifies
Lumen pore is connected with odd number connecting tube 231, and the quantitative lumen pore of even rows is connected with even number connecting tube 232, and the switching pipe 230 passes through
The connection of switching device switching and odd number connecting tube 231, even number connecting tube 232；
The switching device include with switching pipe 230 liquid-in pipe connecting, the left outlet pipe that is connect with odd number connecting tube 231 and
The right outlet pipe being connect with even number connecting tube 232；Liquid-in pipe, left outlet pipe and right outlet pipe are intersected in tube socket；Liquid-in pipe, left outlet pipe and
The outer wall of right outlet pipe is equidistantly laid with connector around axle center；The connector includes the first rod, the second rod, third rod and the
Four rods；First rod is radially extended from connection pipe outer wall；Second rod is axially arranged, and the second rod inner end is vertically fixed
At the top of the first rod；4th rod radially inside extends from the second rod；The tube socket offers through-hole；Through-hole is around tube socket axis
Equidistant arrangement；Tube socket outer wall is arranged with water flowing ring；Water flowing ring and tube socket, which enclose, sets out water flowing chamber；The water flowing ring covers through-hole；
The water flowing chamber is connected to the inner space of connector by through-hole；The water flowing ring is connected with right outlet pipe；The right outlet pipe connection
Water flowing chamber；
Tube socket offers through-hole；Right outlet pipe is connected to the through-hole of tube socket；
The tube socket internal sleeve is equipped with guiding piece；The guiding piece includes guide sleeves, guided rings and guide ribs；The guidance
Set is hollow cylindrical body, and guide sleeves one end is fixedly connected with guided rings, and the outer wall axial direction spaced set of the other end has guide ribs；
The guide ribs inner wall is fixed on guide sleeves, and outer wall is bonded the inner wall of tube socket；Two end chamfer of the guide ribs setting；Through-hole is located at
Between guide ribs and guided rings；Tube socket, guide sleeves and two adjacent guide ribs constitute a guidance cavity.
The present invention can be realized and be switched the liquid-in pipe that pipe 230 connects by above structure, connect with odd number connecting tube 231
Left outlet pipe and the right outlet pipe connecting with even number connecting tube 232 can optionally control its connection type, that is, according to the rotation of motor
Caused by pipeline tilt angle, to switch the switching pipe and the connection of odd number connecting tube 231, even number connecting tube 232.
Embodiment 2
Multichannel sampling valve of the present invention includes shell 132, fixes with spool 127, the shell of the 132 phase sliding contact of shell
Clamping plate 135 and driving spool 127 move in circles the motor 129 of sliding, it is characterised in that: the shell 132 and shell are solid
There is the fluid apertures 137 being connected with sample pump and high throughput analysis device detector and waste liquid pool pipeline, valve on clamp plate 135
Built-in quantitative function on core 127 is slided by motor by shaft coupling 130 and the push-and-pull of transmission shaft 131 when the spool 127 slides
It moves, with switched path.
The sampling valve has sampling work state, sample introduction working condition and valve cleaning state, when it is being sampled
When working condition, odd-numbered line lumen pore 101 on the spool 127,103,105,107,109,111,113,115,117,119,
121,123,125 as sample load channel, respectively on shell 132 and fixing shell 135 sample cell and waste liquid access join
It is logical, sample load is carried out under the promotion of analysis Instrument equipment pump, at the same time, even number line lumen pore 102 on spool 127,104,
106,108,110,112,114,116,118,120,122,124,126 as buffers or carrier fluid channel, respectively with analyzer
Buffer or carrier fluid bottle/pond of device and high pass amount detector connection, the main task of this state be quantitative load sample to be tested,
The Continuous Flow Analysis of sample may be implemented in i.e. this kind of valve of acquisition for nor affecting on instrument detection signal simultaneously；When it is in sample introduction work
Make state i.e. sample analysis state when, odd-numbered line lumen pore 101 on the spool 127,103,105,107,109,111,113,
115,117,119,121,123,125, be loaded under previous state sample to be tested respectively with the buffer of analysis instrument or load
Liquid bottle/pond and high pass amount detector connection, even number line lumen pore 102,104,106,108,110,112,114,116,118,120,
122,124,126 be switched to respectively with pipeline-cleaning access and waste liquid access connection, it should be noted that sample introduction work and valve it is clear
Clean work almost carries out i.e. system simultaneously and completes valve cleaning while sample introduction work, does standard for next group sample analysis
Standby, last consignment of sample analysis terminates to carry out next group sample introduction immediately to save analysis time.
Quantitative lumen pore diameter on the spool 127 is the preferred 1mm of 0.5-3mm, determined volume is 5-500ul preferred
100ul。
The motor is commercially available common program-controlled motor.
127 making material of spool is one of macromolecule inert matrix material PEEK, PS and PDMS, preferably
PPEK。
132 making material of shell is one of macromolecule inert matrix material PEEK, PS and PDMS, preferably
PDMS。
135 making material of shell strap is one in macromolecule inert matrix material PEEK, PS and PDMS
Kind, preferably PEEK.
Quantitative lumen pore is 2-1024 access, preferably 96 accesses on the spool 127.
Fig. 1-5 is please referred to, multichannel sampling valve assembly work of the invention follows principle from the inside to surface from top to bottom with side
Just practical operation, concrete operation method are as follows:
S100. first spool 127 as shown in Figure 3 is connected by 130 motor transmission shaft 131 of motor coupler with motor 129
It is connected to together, forms valve body slides component；
S200. 135 lower half portion of shell strap is fixed on sampling valve mounting platform, then by sample introduction valve shell
Shell strap 135 is inserted by the location hole of shell strap 135 in 132 lower half portion, and the valve body that 1 assembling is obtained is sliding
Dynamic component is packed into shell 132 by the limit hole on shell 132, simultaneously by motor 129 fixed to sampling valve mounting platform；
S300. 132 top half of sample introduction valve shell is anchored to 127 top half of spool by position-limit mechanism, then outer
135 top half of shell strap is anchored to 132 top half of shell by position-limit mechanism while being fixed shell with threaded spindle cap nut
The fixed tight, attention of about 135 two parts of clamping plate cannot influence spool 127 in the driving lower slider of motor 129, so far originally after fixing
The multichannel sampling valve assembly of invention finishes, remaining such as connecting line work can be autonomous according to practical application and analysis instrument platform
Adjustment.
96 samples are once accurately injected into 96 hole elisa Plates using multichannel sampling valve by the present invention.
Multichannel sampling valve prepared by the present invention is applied to the operating method of content of melamine in detection milk, it is specific to walk
It is rapid as follows:
The multichannel sampling valve that assembles from embodiment 3 chooses 96 accesses and is used for 96 samples to be tested once while infusing
Enter to 96 hole elisa Plates, specific implementation step is as follows:
Sample to be tested is that (PBS is prepared clenobuterol hydrochloride solution, and concentration is respectively 0.5ng/ml, 1ng/ml, 1.5ng/
Ml, 2.0ng/ml, 3.0ng/ml), clenobuterol hydrochloride Elisa detection kit (Shenzhen security personnel's limited public affairs of health biotechnology
Department), capital equipment have microplate reader (Thermo Labsystems Multiskan MK3), the Eppendorf liquid relief of various specifications
Rifle (10ul, 20ul, 200ul, 1000ul, 300ul volley of rifle fire), 96 hole elisa Plates:
1. sample pre-treatments and sample detection methods are operated referring to kit shop instruction.
2. the good sample of pre-treatment (500ul) is transferred to 96 hole elisa Plates, the sampling probe of sampling valve front end is put into aforementioned
Parameter (sample introduction is arranged in 96 hole elisa Plates (paying attention to sampling needle point always below liquid level) of 500ul sample, opening pump control software
Amount 50ul, sample introduction flow velocity 200ul/ml) it is sampled operation, software is equally controlled for absorption by sampling valve after sampling
Sample is added to another piece of ELISA Plate for being coated with clenobuterol hydrochloride antigen, and subsequent step is operated referring to kit specification,
Sampling valve sampling probe is put into cleaning solution after cleaning drying after the completion of sample feeding and prepares next sub-sampling.
3. control experiment: the sample of control experiment is drawn to be operated fully according to Elisa kit method.
Experimental result is as shown in table 1, in experiment in order to test between each channel of sampling valve whether can generate cross contamination, into
Specially low concentration and enriched sample are randomly placed in 96 hole elisa Plates when sample, there is no handing between each sample as the result is shown
Pollution is pitched, is respectively less than between big volume low-concentration (0.5ng/ml) is criticized into high concentration (3ng/ml) sample test with batch interior difference
10%, illustrate that multichannel sampling valve provided by the invention can be fully integrated into full-automatic microplate reader, board-washing machine and full-automatic chemical
To save sample analysis time, improve equipment work efficiency in the detection systems such as luminescence immunoassay instrument.
Following table 1 is 2 experimental result of embodiment
Chart label are as follows: clenobuterol hydrochloride addition concentration (ng/ml) in C0, sample to be tested；C, hydrochloric acid in sample is surveyed
Clenbuterol concentration (ng/ml).
Table 1
Embodiment described above only describe the preferred embodiments of the invention, not to model of the invention
It encloses and is defined, without departing from the spirit of the design of the present invention, those of ordinary skill in the art are to technical side of the invention
The various changes and improvements that case is made should all be fallen into the protection scope that claims of the present invention determines.
Claims (9)
1. a kind of multichannel sampling valve, it is characterised in that: including
Shell (132), outer surface are equipped at least two drainage holes (137), are internally provided with spool (127)；And
Motor (129), output shaft are fixed by shaft coupling (130) and the spool (127)；
Wherein, the shell (132) is mounted on shaft coupling (130) by bearing, and the spool (127) is equipped at least two and is ranked
Measure lumen pore, the spool (127) can switch the quantitative lumen pore of odd row according to motor (129) rotation direction, even rows are determined
The opening and closing of lumen pore are measured, the fluid apertures (137) of the shell (132) is connect with switching pipe (230)；
The quantitative lumen pore of the odd row of the spool (127) is connected with odd number connecting tube (231), the quantitative lumen pore connection of even rows
Have even number connecting tube (232), the switching pipe (230) passes through switching device switching and odd number connecting tube (231), even number connecting tube
(232) connection, the switching device include the first extension fixture (210), the second extension fixture (220), first expansion
Device (210), the second extension fixture (220) mutually symmetrical setting,
First extension fixture (210) includes first shell (211), permanent magnet sleeve (212), guide sleeve (213), mandril
(214), electromagnet sleeve (215), heading (216)；
One end of the first shell (211) and the inner surface of shell (132) are fixed, and are fixed with permanent magnetism in first shell (211)
Iron sleeve (212), the permanent magnet sleeve (212) is interior to be set at least two electromagnet sleeves (215), at least two electricity
Magnet sleeve (215) and permanent magnet sleeve (212) clearance fit, the electromagnet sleeve (215) after the energization pass through magnetic induction
It is suspended on permanent magnet sleeve (212) and relative displacement can be generated；It is fixed in at least two electromagnet sleeve (215)
Guide sleeve (213), one end of the guide sleeve (213) are mutually perpendicular to one end of the separate opening of first shell (211) by two
Hinge it is hinged, the guide sleeve (213) is made of aluminum alloy materials, is equipped with mandril (214) in the guide sleeve (213), the top
Bar (214) is made of ferrous material, and the mandril (214) is fixed with heading close to one end of the opening of first shell (211)
(216), the heading can be contacted with the inner surface of mandril；
The two sides of (230) is managed in the heading (216) of first extension fixture (210), the second extension fixture (220) with switching respectively
Contact, switching pipe (230) connect with shell (132) hinge, the odd number connecting tube (231), even number connecting tube (232) with cut
The one end for changing pipe (230) connection is equipped with tubaeform connection bucket (233), close another company of described two connection buckets (233)
Connect the length far from another connection bucket (233) of less than two connection buckets (233) of length of bucket (233).
2. a kind of multichannel sampling valve according to claim 1, it is characterised in that: the motor (129) is program-controlled motor.
3. a kind of multichannel sampling valve according to claim 1, it is characterised in that: the material of the spool (127) is high score
Sub- inert matrix material PEEK, PS or PDMS.
4. a kind of multichannel sampling valve according to claim 1, it is characterised in that: shell (132) making material is height
Molecule inert matrix material PEEK, PS and PDMS.
5. a kind of multichannel sampling valve according to claim 1, it is characterised in that: the face spool of the shell (132)
(127) surface of quantitative lumen pore is equipped with shell strap (135), and the shell strap (135) is equipped at least two
Drainage hole (137).
6. a kind of multichannel sampling valve according to claim 5, it is characterised in that: shell strap (135) production
Material is macromolecule inert matrix material PEEK, PS and PDMS.
7. a kind of multichannel sampling valve according to claim 1, it is characterised in that: the quantitative lumen pore on the spool (127)
Number be 2-1024.
8. a kind of multichannel sampling valve according to claim 1, it is characterised in that: the fluid apertures (137) of the shell (132) with
Switching pipe (230) connection；The quantitative lumen pore of the odd row of the spool (127) is connected with odd number connecting tube (231), even rows
Quantitative lumen pore is connected with even number connecting tube (232), and the switching pipe (230) passes through switching device switching and odd number connecting tube
(231), the connection of even number connecting tube (232)；
The switching device includes fixing seat (301), the first inlet (302), odd number sensor (303), even number sensor
(304), dustpan-shaped liquid separation slot (305)；
The fixing seat (301) connect with the shaft coupling (130), and fixing seat (301) passes through dustpan-shaped liquid separation slot (305) and the
One end of one inlet (302) connection, first inlet (302) is connect with switching pipe (230), the first inlet (302)
The other end connect with dustpan-shaped liquid separation slot (305), one end of the dustpan-shaped liquid separation slot (305) is connect by funnel with odd number
(231) connection is managed, the other end of dustpan-shaped liquid separation slot (305) is connect by funnel with even number connecting tube (232)；
The side of first inlet (302) is equipped with odd number sensor (303), and the other side of the first inlet (302) is equipped with
Even number sensor (304)；
The odd number sensor (303) includes collecting tank, floating ball, drawstring, odd-numbered switch, and the floating ball is located in collecting tank, institute
It states odd-numbered switch and passes through drawstring and the odd-numbered switch for controlling the opening and closing of odd number connecting tube (231), the floating ball
Connection；
The even number sensor (304) includes collecting tank, floating ball, drawstring, even-numbered switch, and the floating ball is located in collecting tank, institute
It states even-numbered switch and passes through drawstring and the even-numbered switch for controlling the opening and closing of even number connecting tube (232), the floating ball
Connection.
9. a kind of multichannel sampling valve according to claim 1, it is characterised in that: the fluid apertures (137) of the shell (132) with
Switching pipe (230) connection；The quantitative lumen pore of the odd row of the spool (127) is connected with odd number connecting tube (231), even rows
Quantitative lumen pore is connected with even number connecting tube (232), and the switching pipe (230) passes through switching device switching and odd number connecting tube
(231), the connection of even number connecting tube (232)；
The switching device include the liquid-in pipe being connect with switching pipe (230), the left outlet pipe that is connect with odd number connecting tube (231) and
The right outlet pipe being connect with even number connecting tube (232)；Liquid-in pipe, left outlet pipe and right outlet pipe are intersected in tube socket；Liquid-in pipe, left outlet pipe
Connector is equidistantly laid with around axle center with the outer wall of right outlet pipe；The connector include the first rod, the second rod, third rod and
4th rod；First rod is radially extended from connection pipe outer wall；Second rod is axially arranged, and the second rod inner end is vertically solid
At the top of the first rod；4th rod radially inside extends from the second rod；The tube socket offers through-hole；Through-hole is in tube socket
Axis is equidistantly arranged；Tube socket outer wall is arranged with water flowing ring；Water flowing ring and tube socket, which enclose, sets out water flowing chamber；The water flowing ring covers logical
Hole；The water flowing chamber is connected to the inner space of connector by through-hole；The water flowing ring is connected with right outlet pipe；The right outlet pipe connects
Water cavity all；
Tube socket offers through-hole；Right outlet pipe is connected to the through-hole of tube socket；
The tube socket internal sleeve is equipped with guiding piece；The guiding piece includes guide sleeves, guided rings and guide ribs；The guide sleeves are
Hollow cylindrical body, guide sleeves one end are fixedly connected with guided rings, and the outer wall axial direction spaced set of the other end has guide ribs；It is described
Guide ribs inner wall is fixed on guide sleeves, and outer wall is bonded the inner wall of tube socket；Two end chamfer of the guide ribs setting；Through-hole is located at guidance
Between item and guided rings；Tube socket, guide sleeves and two adjacent guide ribs constitute a guidance cavity.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610587541.8A CN106195331B (en) | 2016-07-22 | 2016-07-22 | A kind of multichannel sampling valve |
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| CN201610587541.8A CN106195331B (en) | 2016-07-22 | 2016-07-22 | A kind of multichannel sampling valve |
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| CN106195331B true CN106195331B (en) | 2019-04-26 |
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| CN109374798B (en) * | 2018-10-16 | 2020-11-03 | 安徽皖仪科技股份有限公司 | Multi-tube combined type sample injection valve and using method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103574129A (en) * | 2012-07-20 | 2014-02-12 | 通用汽车环球科技运作有限责任公司 | Electronically controlled valve assembly |
| CN104373630A (en) * | 2013-08-17 | 2015-02-25 | 宋久林 | Rotary proportional reversing valve |
| CN105402441A (en) * | 2014-09-10 | 2016-03-16 | 株式会社丰田自动织机 | Rotary valve device |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5707076B2 (en) * | 2010-09-22 | 2015-04-22 | 株式会社不二工機 | Multi-way selector valve |
| JP6014865B2 (en) * | 2012-03-22 | 2016-10-26 | 株式会社エンプラス | Liquid dividing method and liquid dividing kit |
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2016
- 2016-07-22 CN CN201610587541.8A patent/CN106195331B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103574129A (en) * | 2012-07-20 | 2014-02-12 | 通用汽车环球科技运作有限责任公司 | Electronically controlled valve assembly |
| CN104373630A (en) * | 2013-08-17 | 2015-02-25 | 宋久林 | Rotary proportional reversing valve |
| CN105402441A (en) * | 2014-09-10 | 2016-03-16 | 株式会社丰田自动织机 | Rotary valve device |
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