CN106188936A - A kind of high-barrier PVC pharmaceutical pack film and production technology thereof - Google Patents
A kind of high-barrier PVC pharmaceutical pack film and production technology thereof Download PDFInfo
- Publication number
- CN106188936A CN106188936A CN201610540146.4A CN201610540146A CN106188936A CN 106188936 A CN106188936 A CN 106188936A CN 201610540146 A CN201610540146 A CN 201610540146A CN 106188936 A CN106188936 A CN 106188936A
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- Prior art keywords
- pharmaceutical pack
- stabilizer
- pvc
- pack film
- barrier
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Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L27/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
- C08L27/02—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L27/04—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
- C08L27/06—Homopolymers or copolymers of vinyl chloride
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2201/00—Properties
- C08L2201/14—Gas barrier composition
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/16—Applications used for films
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/03—Polymer mixtures characterised by other features containing three or more polymers in a blend
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
A kind of high-barrier PVC pharmaceutical pack film and production technology thereof, relate to acceptable packaging material field.According to mass fraction ratio, it is made up of following raw material: PVC resin powder: 100 parts, stabilizer: 1.0 2.5, interior lubrication prescription: 0.5 1.5 parts, outer lubrication prescription: 0.2 1.0 parts, processing aid: 1.0 4.0 parts, MBS resin: 3.0 9.0 parts, Graphene: 0.1 3.0 parts.The PVC pharmaceutical pack film of the present invention has relative to prior art that thickness is uniform, surface gloss is high and has the advantage of high barrier；Steam penetrating capacity is from 1 2g/m2* about 24h is reduced to 0.5 1g/m2*24h；Oxygen transit dose is from 14 18g/m2* 24h*0.1mpa is reduced to 3g/m2* within 24h*0.1mpa.
Description
Technical field
The present invention relates to acceptable packaging material field, be specially a kind of high-barrier PVC pharmaceutical pack film and production technology thereof.
Background technology
The most the most frequently used PTP pharmaceutical pack film packaging is all the base material made of PVC, and PVC low cost, combination property is excellent
Different.
But in the middle of actually used, Some Drugs is very sensitive to humidity, oxygen, and the barrier property of existing PVC can not be expired
Foot needs.
Summary of the invention
It is an object of the invention to provide a kind of high-barrier PVC pharmaceutical pack film and production technology thereof, there is technique simple, resistance to
Corrode the advantages such as strong, lighter in weight and high obstructing performance.
The technical scheme realizing above-mentioned purpose is: a kind of high-barrier PVC pharmaceutical pack film, it is characterised in that: according to quality
Portion rate, is made up of following raw material: PVC resin powder: 100 parts, stabilizer: 1.0-2.5, interior lubrication prescription: 0.5-1.5 part, outer lubrication prescription:
0.2-1.0 part, processing aid: 1.0-4.0 part, MBS resin: 3.0-9.0 part, Graphene: 0.1-3.0 part.
Further, described stabilizer be Methyltin stabiliser, octyl tin stabilizer, rare-earth stabilizer, calcium zinc stabilizer,
One or more in barium zinc stabilizer.
Further, processing aid is methyl methacrylate-acrylate copolymer.
Further, the degree of polymerization of PVC resin powder is 700 or 800.
Further, the model of described interior lubrication prescription is G16.
The production technology of above-mentioned high-barrier PVC pharmaceutical pack film, it is characterised in that comprise the following steps:
A, material put in high-speed mixer by dosage and mix, make temperature of charge by the physical friction between raw material
Rising to 100-120 DEG C, the rotating speed of high-speed mixer is: 2000-3000 rev/min；
B, the material after mixed at high speed is sent in low speed mixer remix, make temperature of charge be down to 40-60 DEG C, low
The rotating speed of speed mixer is 50-500 rev/min；
Extruder extrusion plasticizing sent into by c, material after mixed on low speed, and extruder temperature is 140-200 DEG C；
Material after d, plasticizing is delivered to calender, is processed into thin film, calendering workshop section temperature by the calendering workshop section of calender
Degree 150-220, then it is cooled to 30-60 DEG C by the chill roll group of calender.
Further, the outer wall of the hybrid chamber of described low speed mixer is provided with water-cooling jacket.
Preferably, above-mentioned steps a is initially charged PVC resin powder, treats that the temperature of high-speed mixer hybrid chamber rises to 45-50 DEG C
Time, add stabilizer and interior lubrication prescription, rise to add outer lubrication prescription, processing aid, MBS resin and Graphene when 75-80 DEG C.
Stabilizer is mainly used in maintaining the stability of product, and outer lubrication prescription, processing aid, MBS resin and Graphene are such as
Fruit and stabilizer are simultaneously introduced meeting Vapor recovery unit agent, cause the effectiveness of stabilizer normally not play, affect product quality.
Beneficial effects of the present invention:
1, the PVC pharmaceutical pack film of the present invention has relative to prior art that thickness is uniform, surface gloss is high and has
The advantage having high barrier；Steam penetrating capacity is from 1-2g/m2* about 24h is reduced to 0.5-1g/m2*24h；Oxygen transit dose from
14-18g/m2* 24h*0.1mpa is reduced to 3g/m2* within 24h*0.1mpa.
2, the preparation technology of the present invention is simple, low cost.
3, the PVC pharmaceutical pack film of the present invention is widely used, and can apply to the various occasion high to barrier requirement.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme clearer, below in conjunction with specific embodiment, the present invention is entered
Row further describes.
Below one high-barrier PVC pharmaceutical pack film of the present invention and production technology thereof are described in detail below.
Embodiment 1
A kind of high-barrier PVC pharmaceutical pack film, according to mass fraction ratio, is made up of following raw material: PVC resin powder: 100
Part, stabilizer: 1.0, interior lubrication prescription: 1.0 parts, outer lubrication prescription: 1.0 parts, processing aid: 1.0 parts, MBS resin: 6.0 parts, Graphene:
3.0 part.
Wherein, processing aid is methyl methacrylate-acrylate copolymer；The degree of polymerization of PVC resin powder is 700；
The model of interior lubrication prescription is G16.
The production technology of above-mentioned high-barrier PVC pharmaceutical pack film, it is characterised in that comprise the following steps:
A, first PVC resin powder is put into by dosage high-speed mixer stirring, treat the temperature of high-speed mixer hybrid chamber
When rising to 45 DEG C, add stabilizer and interior lubrication prescription, rise to add outer lubrication prescription, processing aid, MBS resin and graphite when 75 DEG C
Alkene, makes temperature of charge rise to 100 DEG C by the physical friction between raw material, and the rotating speed of high-speed mixer is: 2000 revs/min；
B, material after mixed at high speed is sent in low speed mixer and remixed, the outer wall of the hybrid chamber of low speed mixer
Being provided with water-cooling jacket, make temperature of charge be down to 40 DEG C, the rotating speed of low speed mixer is 50 revs/min；
Extruder extrusion plasticizing sent into by c, material after mixed on low speed, and extruder temperature is 140 DEG C；
Material after d, plasticizing is delivered to calender, is processed into thin film, calendering workshop section temperature by the calendering workshop section of calender
Degree 150, then it is cooled to 30 DEG C by the chill roll group of calender.
Embodiment 2
A kind of high-barrier PVC pharmaceutical pack film, according to mass fraction ratio, is made up of following raw material: PVC resin powder: 100
Part, stabilizer: 2.5, interior lubrication prescription: 0.5 part, outer lubrication prescription: 0.6 part, processing aid: 4.0 parts, MBS resin: 3.0 parts, Graphene:
1.5 part.
Wherein, processing aid is methyl methacrylate-acrylate copolymer；The degree of polymerization of PVC resin powder is 800；
The model of interior lubrication prescription is G16.
The production technology of above-mentioned high-barrier PVC pharmaceutical pack film, it is characterised in that comprise the following steps:
A, first PVC resin powder is put into by dosage high-speed mixer stirring, treat the temperature of high-speed mixer hybrid chamber
When rising to 50 DEG C, add stabilizer and interior lubrication prescription, rise to add outer lubrication prescription, processing aid, MBS resin and graphite when 80 DEG C
Alkene, makes temperature of charge rise to 120 DEG C by the physical friction between raw material, and the rotating speed of high-speed mixer is: 3000 revs/min；
B, material after mixed at high speed is sent in low speed mixer and remixed, the outer wall of the hybrid chamber of low speed mixer
Being provided with water-cooling jacket, make temperature of charge be down to 60 DEG C, the rotating speed of low speed mixer is 500 revs/min；
Extruder extrusion plasticizing sent into by c, material after mixed on low speed, and extruder temperature is 200 DEG C；
Material after d, plasticizing is delivered to calender, is processed into thin film, calendering workshop section temperature by the calendering workshop section of calender
Degree 185, then it is cooled to 60 DEG C by the chill roll group of calender.
Embodiment 3
A kind of high-barrier PVC pharmaceutical pack film, according to mass fraction ratio, is made up of following raw material: PVC resin powder: 100
Part, stabilizer: 1.8, interior lubrication prescription: 1.5 parts, outer lubrication prescription: 0.2 part, processing aid: 2.5 parts, MBS resin: 9.0 parts, Graphene:
0.1 part.
Wherein, processing aid is methyl methacrylate-acrylate copolymer；The degree of polymerization of PVC resin powder is 700；
The model of interior lubrication prescription is G16.
The production technology of above-mentioned high-barrier PVC pharmaceutical pack film, it is characterised in that comprise the following steps:
A, first PVC resin powder is put into by dosage high-speed mixer stirring, treat the temperature of high-speed mixer hybrid chamber
When rising to 47 DEG C, add stabilizer and interior lubrication prescription, rise to add outer lubrication prescription, processing aid, MBS resin and graphite when 78 DEG C
Alkene, makes temperature of charge rise to 110 DEG C by the physical friction between raw material, and the rotating speed of high-speed mixer is: 2500 revs/min；
B, material after mixed at high speed is sent in low speed mixer and remixed, the outer wall of the hybrid chamber of low speed mixer
Being provided with water-cooling jacket, make temperature of charge be down to 50 DEG C, the rotating speed of low speed mixer is 270 revs/min；
Extruder extrusion plasticizing sent into by c, material after mixed on low speed, and extruder temperature is 170 DEG C；
Material after d, plasticizing is delivered to calender, is processed into thin film, calendering workshop section temperature by the calendering workshop section of calender
Degree 220, then it is cooled to 45 DEG C by the chill roll group of calender.
Stabilizer in above-mentioned 3 embodiments can be Methyltin stabiliser, octyl tin stabilizer, rare-earth stabilizer, calcium
One or more in zinc stabilizer, barium zinc stabilizer.
The foregoing is only embodiments of the invention, not thereby limit the scope of the claims of the present invention, every utilize this
The equivalent transformation that bright description is made, or directly or indirectly it is used in other relevant technical fields, the most in like manner it is included in this
In bright scope of patent protection.
Claims (8)
1. a high-barrier PVC pharmaceutical pack film, it is characterised in that: according to mass fraction ratio, it is made up of following raw material: PVC tree
Cosmetics: 100 parts, stabilizer: 1.0-2.5, interior lubrication prescription: 0.5-1.5 part, outer lubrication prescription: 0.2-1.0 part, processing aid: 1.0-4.0
Part, MBS resin: 3.0-9.0 part, Graphene: 0.1-3.0 part.
A kind of high-barrier PVC pharmaceutical pack film the most according to claim 1, it is characterised in that: described stabilizer is methyl
One or more in stannum stabilizer, octyl tin stabilizer, rare-earth stabilizer, calcium zinc stabilizer, barium zinc stabilizer.
A kind of high-barrier PVC pharmaceutical pack film the most according to claim 1, it is characterised in that: processing aid is methyl-prop
E pioic acid methyl ester-acrylate copolymer.
A kind of high-barrier PVC pharmaceutical pack film the most according to claim 1, it is characterised in that: the degree of polymerization of PVC resin powder
It is 700 or 800.
A kind of high-barrier PVC pharmaceutical pack film the most according to claim 1, it is characterised in that: the model of described interior lubrication prescription
For G16.
6., according to the production technology of the high-barrier PVC pharmaceutical pack film described in claim any one of claim 1-5, it is special
Levy and be, comprise the following steps:
A, material put in high-speed mixer by dosage and mix, make temperature of charge rise to by the physical friction between raw material
100-120 DEG C, the rotating speed of high-speed mixer is: 2000-3000 rev/min；
B, being sent in low speed mixer by the material after mixed at high speed and remix, make temperature of charge be down to 40-60 DEG C, low speed mixes
The rotating speed of conjunction machine is 50-500 rev/min；
Extruder extrusion plasticizing sent into by c, material after mixed on low speed, and extruder temperature is 140-200 DEG C；
Material after d, plasticizing is delivered to calender, is processed into thin film, calendering workshop section temperature by the calendering workshop section of calender
150-220, then it is cooled to 30-60 DEG C by the chill roll group of calender.
The production technology of high-barrier PVC pharmaceutical pack film the most according to claim 6, it is characterised in that described low speed mixes
The outer wall of the hybrid chamber of conjunction machine is provided with water-cooling jacket.
The production technology of high-barrier PVC pharmaceutical pack film the most according to claim 6, it is characterised in that first add in step a
Enter PVC resin powder, when the temperature of high-speed mixer hybrid chamber rises to 45-50 DEG C, add stabilizer and interior lubrication prescription, rise to 75-
Outer lubrication prescription, processing aid, MBS resin and Graphene is added when 80 DEG C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610540146.4A CN106188936A (en) | 2016-07-08 | 2016-07-08 | A kind of high-barrier PVC pharmaceutical pack film and production technology thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610540146.4A CN106188936A (en) | 2016-07-08 | 2016-07-08 | A kind of high-barrier PVC pharmaceutical pack film and production technology thereof |
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| CN106188936A true CN106188936A (en) | 2016-12-07 |
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| CN201610540146.4A Pending CN106188936A (en) | 2016-07-08 | 2016-07-08 | A kind of high-barrier PVC pharmaceutical pack film and production technology thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107226973A (en) * | 2017-06-20 | 2017-10-03 | 苏州奥宇包装科技有限公司 | A kind of preparation method of woodwork packaging film |
| CN107226978A (en) * | 2017-06-20 | 2017-10-03 | 苏州奥宇包装科技有限公司 | A kind of preparation method of woodwork packaging material |
| CN107353561A (en) * | 2017-06-20 | 2017-11-17 | 苏州奥宇包装科技有限公司 | A kind of preparation method of packaging film |
| CN110819028A (en) * | 2018-08-10 | 2020-02-21 | 江苏永润包装材料有限公司 | Cold stamping forming composite film for medicine packaging and preparation process thereof |
| CN111675868A (en) * | 2020-06-03 | 2020-09-18 | 无锡宏义高分子材料科技有限公司 | High-glossiness low-transmittance PVC (polyvinyl chloride) base material and preparation method thereof |
| CN114644771A (en) * | 2022-04-15 | 2022-06-21 | 山东金阳光医药包装有限公司 | Polyvinyl chloride medicine package sheet with anti-fouling and antibacterial functions and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107226973A (en) * | 2017-06-20 | 2017-10-03 | 苏州奥宇包装科技有限公司 | A kind of preparation method of woodwork packaging film |
| CN107226978A (en) * | 2017-06-20 | 2017-10-03 | 苏州奥宇包装科技有限公司 | A kind of preparation method of woodwork packaging material |
| CN107353561A (en) * | 2017-06-20 | 2017-11-17 | 苏州奥宇包装科技有限公司 | A kind of preparation method of packaging film |
| CN110819028A (en) * | 2018-08-10 | 2020-02-21 | 江苏永润包装材料有限公司 | Cold stamping forming composite film for medicine packaging and preparation process thereof |
| CN111675868A (en) * | 2020-06-03 | 2020-09-18 | 无锡宏义高分子材料科技有限公司 | High-glossiness low-transmittance PVC (polyvinyl chloride) base material and preparation method thereof |
| CN114644771A (en) * | 2022-04-15 | 2022-06-21 | 山东金阳光医药包装有限公司 | Polyvinyl chloride medicine package sheet with anti-fouling and antibacterial functions and preparation method thereof |
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Application publication date: 20161207 |