CN105295254A - Medical film material and preparation method thereof - Google Patents
Medical film material and preparation method thereof Download PDFInfo
- Publication number
- CN105295254A CN105295254A CN201510815494.3A CN201510815494A CN105295254A CN 105295254 A CN105295254 A CN 105295254A CN 201510815494 A CN201510815494 A CN 201510815494A CN 105295254 A CN105295254 A CN 105295254A
- Authority
- CN
- China
- Prior art keywords
- film material
- polyvinylpyrrolidone
- medical
- weight
- medical thin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses a medical film material. The medical film material consists of the following components by weight: 30-40% of polyvinyl chloride resin, 10%-25% of starch, 1%-5% of hydroxymethyl cellulose, 2%-5% of polyvinyl pyrrolidone, 1-5% of methyl 4-hydroxybenzoate, 1-5% of dibutyl phthalate, 1-5% of TPU, 3-5% of linoleic acid, and the balance epoxidized soybean oil. The invention also discloses a preparation method of the medical film material. According to the invention, PVC, a surfactant and an antibacterial agent are employed to prepare the novel medical film material, which has the advantages of green, low temperature resistance, high temperature resistance and good antibacterial effect, and can be used for manufacturing medical bedspreads, operation pads, disposable gloves and medical film bags, etc.
Description
Technical field
The present invention relates to a kind of medicinal preparation, particularly relate to a kind of medical thin-film material and preparation method thereof.
Background technology
Pvc material itself is comparatively hard, and after adding softening agent, pvc material will become soft and flexible, is convenient to forming process, can makes the medical product of different shape, be widely used in the manufacture of medical product at present.
But at present conventional medical thin-film material is mostly not low temperature resistant, poor air permeability, therefore, develop a kind ofly to fill a prescription rationally, stable performance, resistance to bending, the medical thin-film material with good ventilation property and lower temperature resistance be a problem urgently to be resolved hurrily.
Summary of the invention
In order to solve the problem, the invention provides and a kind ofly fill a prescription rationally, stable performance, resistance to bending, there is good ventilation property and the medical thin-film material of lower temperature resistance.
The technical solution used in the present invention is: a kind of medical thin-film material, calculate by weight and be made up of following component: polyvinyl chloride (PVC) RESINS 30-40%, starch 10-25%, Walocel MT 20.000PV 1-5%, polyvinylpyrrolidone 2-5%, methyl p-hydroxybenzoate 1-5%, dibutyl phthalate 1-5%, TPU1-5%, linolic acid 3-5%, surplus is epoxy soybean oil;
Further, described polyvinylpyrrolidone is polyvinylpyrrolidone-K30;
Again further, calculate by weight and be made up of following component: polyvinyl chloride (PVC) RESINS 35%, starch 25%, Walocel MT 20.000PV 5%, polyvinylpyrrolidone-K305%, methyl p-hydroxybenzoate 5%, dibutyl phthalate 5%, TPU5%, linolic acid 5%, surplus is epoxy soybean oil;
Or, calculate by weight and be made up of following component: polyvinyl chloride (PVC) RESINS 38%, starch 20%, Walocel MT 20.000PV 3%, polyvinylpyrrolidone-K305%, methyl p-hydroxybenzoate 3%, dibutyl phthalate 3%, TPU5%, linolic acid 5%, surplus is epoxy soybean oil.
Present invention also offers the preparation method of above-mentioned medical thin-film material, its concrete steps are as follows:
(1) parts by weight by formula are calculated the starch obtained to carry out milled processed and reach 200-300 order, add appropriate amount of deionized water, in mixing machine, mixed pre-gelatinized;
(2) parts by weight by formula being calculated the described polyvinyl chloride (PVC) RESINS, Walocel MT 20.000PV, polyvinylpyrrolidone, methyl p-hydroxybenzoate, dibutyl phthalate, TPU, linolic acid, the epoxy soybean oil that obtain adds in the above-mentioned mixing machine completing pre-gelatinized step, vibrating dispersion at 25-35 DEG C, rotating speed is 800-1200rpm, and jitter time is 0.5-1h;
(3) suspension obtained in step (2) is shaping and dry film forming by casting apparatus, and obtain product medical thin-film material through fixating shape step;
Further, being dried into film temperature described in is 65-75 DEG C;
Again further, fixating shape step described in step (3) is immersed by the film of flow casting molding by the solution of the ammoniacal liquor of mass concentration 15% and mass concentration 80% ethanol 2:3 mixed preparing by volume, and soak time is 5-25 minute.
Beneficial effect of the present invention:
The present invention adopts a kind of novel medical thin-film material of vegetables oil, tensio-active agent, anti-infective drugs, formula rationally, stable performance, resistance to bending, there is good ventilation property and lower temperature resistance, high thermal resistance, biocidal property, can be used for manufacturing pharmaceutical bedcover, operation pad, disposable glove, medical film bag etc.
Embodiment
Embodiment 1:
Calculate by weight and be made up of following component: polyvinyl chloride (PVC) RESINS 35%, starch 25%, Walocel MT 20.000PV 5%, polyvinylpyrrolidone-K305%, methyl p-hydroxybenzoate 5%, dibutyl phthalate 5%, TPU5%, linolic acid 5%, surplus is epoxy soybean oil
Its preparation process step:
(1) parts by weight by formula are calculated the starch obtained to carry out milled processed and reach 200-300 order, add appropriate amount of deionized water, in mixing machine, mixed pre-gelatinized;
(2) parts by weight by formula being calculated the described polyvinyl chloride (PVC) RESINS, Walocel MT 20.000PV, polyvinylpyrrolidone, methyl p-hydroxybenzoate, dibutyl phthalate, TPU, linolic acid, the epoxy soybean oil that obtain adds in the above-mentioned mixing machine completing pre-gelatinized step, vibrating dispersion at 25 DEG C, rotating speed is 800rpm, and jitter time is 1h;
(3) suspension that obtains in step (2) is shaping and dry film forming at 65 DEG C by casting apparatus, and the film of flow casting molding is immersed by the solution of the ammoniacal liquor of mass concentration 15% and mass concentration 80% ethanol 2:3 mixed preparing by volume, soak time is 20 minutes, obtains product medical thin-film material.
Embodiment 2:
Calculate by weight and be made up of following component: wheatgerm oil 15%, Walocel MT 20.000PV 5%, polyvinylpyrrolidone-K306%, tetracaine 2%, methyl p-hydroxybenzoate 5%, tween-80 3%, surplus is deionized water.
Its preparation process step:
(1) parts by weight by formula are calculated the starch obtained to carry out milled processed and reach 200-300 order, add appropriate amount of deionized water, in mixing machine, mixed pre-gelatinized;
(2) parts by weight by formula being calculated the described polyvinyl chloride (PVC) RESINS, Walocel MT 20.000PV, polyvinylpyrrolidone, methyl p-hydroxybenzoate, dibutyl phthalate, TPU, linolic acid, the epoxy soybean oil that obtain adds in the above-mentioned mixing machine completing pre-gelatinized step, vibrating dispersion at 35 DEG C, rotating speed is 1200rpm, and jitter time is 1h;
(3) suspension that obtains in step (2) is shaping and dry film forming at 65 DEG C by casting apparatus, and the film of flow casting molding is immersed by the solution of the ammoniacal liquor of mass concentration 15% and mass concentration 80% ethanol 2:3 mixed preparing by volume, soak time is 20 minutes, obtains product medical thin-film material.
Embodiment 3:
Embodiment 1-2 fill a prescription model that the medical thin-film material that obtains produces with Zhejiang vast sea macromolecular material company limited after making medical film bag be WY9050G1 medical film bag compared with its various aspects of performance see the following form:
Table 1 test-results
As seen from the above table, select appropriate in medical thin-film material formula of the present invention, there is high temperature resistant, low temperature resistant effect preferably, can be used in the purposes such as high-temperature sterilization and low temperature storage blood plasma.
Embodiment 4:
Fill a prescription model that the medical thin-film material that obtains produces with Zhejiang vast sea macromolecular material company limited after making medical film bag of embodiment 1-2 is the medical film bag of WY9050G1, carry out bacteriostasis rate experiment, intestinal bacteria+streptococcus aureus that wherein bacteriostasis rate adopts this area common is the object of observation, adopt normal condition to be padded in container with medical film bag and carry out microbial culture experiment, its bacteriostasis property of comparing sees the following form:
Table 2 bacteria inhibition assay result
| Bacteriostasis rate/% (incubation time is 48 hours) | |
| Embodiment 1 | 99.5 |
| Embodiment 2 | 99.8 |
| WY9050G1 | 15.2 |
As seen from the above table, medical thin-film material formula of the present invention is reasonable, has good fungistatic effect.
Above-described embodiment, just in order to technical conceive of the present invention and feature are described, its objective is and is one of ordinary skilled in the art can be understood content of the present invention and implement according to this, can not limit the scope of the invention with this.The change of every equivalence done by the essence of content of the present invention or modification, all should be encompassed in protection scope of the present invention.
Claims (7)
1. a medical thin-film material, it is characterized in that, calculate by weight and be made up of following component: polyvinyl chloride (PVC) RESINS 30-40%, starch 10-25%, Walocel MT 20.000PV 1-5%, polyvinylpyrrolidone 2-5%, methyl p-hydroxybenzoate 1-5%, dibutyl phthalate 1-5%, TPU1-5%, linolic acid 3-5%, surplus is epoxy soybean oil.。
2. a kind of medical thin-film material as claimed in claim 1, is characterized in that, described polyvinylpyrrolidone is polyvinylpyrrolidone-K30.
3. a kind of medical thin-film material as described in any one of claim 1 or 2, it is characterized in that, calculate by weight and be made up of following component: polyvinyl chloride (PVC) RESINS 35%, starch 25%, Walocel MT 20.000PV 5%, polyvinylpyrrolidone-K305%, methyl p-hydroxybenzoate 5%, dibutyl phthalate 5%, TPU5%, linolic acid 5%, surplus is epoxy soybean oil.
4. a kind of medical thin-film material as described in any one of claim 1 or 2, it is characterized in that, calculate by weight and be made up of following component: polyvinyl chloride (PVC) RESINS 38%, starch 20%, Walocel MT 20.000PV 3%, polyvinylpyrrolidone-K305%, methyl p-hydroxybenzoate 3%, dibutyl phthalate 3%, TPU5%, linolic acid 5%, surplus is epoxy soybean oil.
5. the preparation method of a kind of medical thin-film material as described in any one of claim 1-2, is characterized in that:
(1) parts by weight by formula are calculated the starch obtained to carry out milled processed and reach 200-300 order, add appropriate amount of deionized water, in mixing machine, mixed pre-gelatinized;
(2) parts by weight by formula being calculated the described polyvinyl chloride (PVC) RESINS, Walocel MT 20.000PV, polyvinylpyrrolidone, methyl p-hydroxybenzoate, dibutyl phthalate, TPU, linolic acid, the epoxy soybean oil that obtain adds in the above-mentioned mixing machine completing pre-gelatinized step, vibrating dispersion at 25-35 DEG C, rotating speed is 800-1200rpm, and jitter time is 0.5-1h;
(3) suspension obtained in step (2) is shaping and dry film forming by casting apparatus, and obtain product medical thin-film material through fixating shape step.
6. the preparation method of a kind of medical thin-film material as claimed in claim 5, is characterized in that: described in be dried into film temperature be 65-75 DEG C.
7. the preparation method of a kind of medical thin-film material as claimed in claim 5, it is characterized in that: fixating shape step described in step (3) is immersed by the film of flow casting molding by the solution of the ammoniacal liquor of mass concentration 15% and mass concentration 80% ethanol 2:3 mixed preparing by volume, and soak time is 5-25 minute.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510815494.3A CN105295254A (en) | 2015-11-23 | 2015-11-23 | Medical film material and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510815494.3A CN105295254A (en) | 2015-11-23 | 2015-11-23 | Medical film material and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105295254A true CN105295254A (en) | 2016-02-03 |
Family
ID=55193140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510815494.3A Pending CN105295254A (en) | 2015-11-23 | 2015-11-23 | Medical film material and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105295254A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105885283A (en) * | 2016-04-28 | 2016-08-24 | 苏州市鼎立包装有限公司 | PVC (polyvinyl chloride) stretch film and method for preparing same |
| CN106188936A (en) * | 2016-07-08 | 2016-12-07 | 江苏金材科技有限公司 | A kind of high-barrier PVC pharmaceutical pack film and production technology thereof |
| CN106279780A (en) * | 2016-08-02 | 2017-01-04 | 安徽美翔塑业有限公司 | A kind of starch polyvinyl chloride resin is blended degradable patch bone bag and preparation method thereof |
| CN106366620A (en) * | 2016-08-30 | 2017-02-01 | 何仁英 | Transfusion bag material containing polyurethane and preparation method of material |
| CN109082036A (en) * | 2018-08-15 | 2018-12-25 | 方金婷 | A kind of preparation method and applications of compound antibacterial plastic film |
| CN109135252A (en) * | 2018-06-27 | 2019-01-04 | 安徽嘉明新材料科技有限公司 | A kind of degradable TPU membrane and its preparation process |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5009648A (en) * | 1989-03-22 | 1991-04-23 | E. R. Squibb & Sons, Inc. | Starch containing film ostomy pouches |
| CN101979434A (en) * | 2010-11-24 | 2011-02-23 | 成都市新津事丰医疗器械有限公司 | Low-temperature resistant medicinal PVC modified material |
| CN104877182A (en) * | 2015-05-22 | 2015-09-02 | 苏州市贝克生物科技有限公司 | Method for preparing medical plastic |
| CN104877268A (en) * | 2015-05-22 | 2015-09-02 | 苏州市贝克生物科技有限公司 | Preparation method of environment-friendly bacteriostatic medical film |
-
2015
- 2015-11-23 CN CN201510815494.3A patent/CN105295254A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5009648A (en) * | 1989-03-22 | 1991-04-23 | E. R. Squibb & Sons, Inc. | Starch containing film ostomy pouches |
| CN101979434A (en) * | 2010-11-24 | 2011-02-23 | 成都市新津事丰医疗器械有限公司 | Low-temperature resistant medicinal PVC modified material |
| CN104877182A (en) * | 2015-05-22 | 2015-09-02 | 苏州市贝克生物科技有限公司 | Method for preparing medical plastic |
| CN104877268A (en) * | 2015-05-22 | 2015-09-02 | 苏州市贝克生物科技有限公司 | Preparation method of environment-friendly bacteriostatic medical film |
Non-Patent Citations (2)
| Title |
|---|
| 彭毓华: "微生物降解淀粉——聚氯乙烯（PVC）薄膜的试验研究", 《太原工业大学学报》 * |
| 马青兰等: "淀粉在塑料研制中的应用I 工物理混合法制备淀粉基塑料", 《太原工业大学学报》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105885283A (en) * | 2016-04-28 | 2016-08-24 | 苏州市鼎立包装有限公司 | PVC (polyvinyl chloride) stretch film and method for preparing same |
| CN106188936A (en) * | 2016-07-08 | 2016-12-07 | 江苏金材科技有限公司 | A kind of high-barrier PVC pharmaceutical pack film and production technology thereof |
| CN106279780A (en) * | 2016-08-02 | 2017-01-04 | 安徽美翔塑业有限公司 | A kind of starch polyvinyl chloride resin is blended degradable patch bone bag and preparation method thereof |
| CN106366620A (en) * | 2016-08-30 | 2017-02-01 | 何仁英 | Transfusion bag material containing polyurethane and preparation method of material |
| CN109135252A (en) * | 2018-06-27 | 2019-01-04 | 安徽嘉明新材料科技有限公司 | A kind of degradable TPU membrane and its preparation process |
| CN109135252B (en) * | 2018-06-27 | 2020-11-03 | 安徽嘉明新材料科技有限公司 | Degradable TPU film and preparation process thereof |
| CN109082036A (en) * | 2018-08-15 | 2018-12-25 | 方金婷 | A kind of preparation method and applications of compound antibacterial plastic film |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105295254A (en) | Medical film material and preparation method thereof | |
| CN104499094B (en) | A kind of ultra-fine rubber latex thread and manufacture method thereof | |
| CN102875936B (en) | DEHP (di-2-ethylhexyl phthalate)-free medical PVC (polyvinyl chloride) paste material | |
| EP3789411A3 (en) | Polymer resin | |
| CN103788544A (en) | Antibacterial polyvinyl chloride (PVC) composite material for baby swim ring and preparation method thereof | |
| CN105038017A (en) | Medical thin film material | |
| CN104650290A (en) | Polymer nano ZnO compound antibacterial agent for synthetic leathers based on in-situ polymerization process and preparation method of polymer nano ZnO compound antibacterial agent | |
| CN105037950A (en) | Modified polypropylene plastic | |
| CN103772866B (en) | A kind of high temperature resistant food package film and preparation method thereof | |
| CN107674644A (en) | A kind of antimicrobial sealing glue and preparation method thereof | |
| CN103589063A (en) | High-temperature resistant antibacterial plastic | |
| CN107216634A (en) | Nano silver grain string composite packaging box of degradable antibacterial and preparation method thereof | |
| CN103349197A (en) | Technology method for forming convenient bean jelly at one time | |
| CN103587016B (en) | A kind of antiseptic rubber gloves and preparation method thereof | |
| CN104403281B (en) | A kind of medical fibre based high molecular material and its preparation method | |
| CN103554279B (en) | The composite modified starch of alternative gelatin and application | |
| CN103756284B (en) | A kind of production technology of heat-insulation breathable fabric thin film | |
| CN105295252A (en) | Medical PVC infusion bag | |
| CN104403339A (en) | Blood transfusion latex pipe and preparation method thereof | |
| CN113881074A (en) | Preparation method of thin polyurethane medical gloves | |
| CN107057039A (en) | A kind of phosphorous, nitrogen epoxy resin flame retardant curing agent and preparation method thereof | |
| CN105153582A (en) | PVC (polyvinyl chloride) transparent hard sheet | |
| CN102366402A (en) | Scopolamine hydrobromide injection and production technology | |
| CN107903684A (en) | A kind of organic silicon water-proofing agent prescription | |
| CN204305985U (en) | The anti-chocolate sticky stick system of a kind of cooling fast |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160203 |
|
| RJ01 | Rejection of invention patent application after publication |