CN106178596B - Solid Phase Extraction pressue device - Google Patents
Solid Phase Extraction pressue device Download PDFInfo
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- CN106178596B CN106178596B CN201610818644.0A CN201610818644A CN106178596B CN 106178596 B CN106178596 B CN 106178596B CN 201610818644 A CN201610818644 A CN 201610818644A CN 106178596 B CN106178596 B CN 106178596B
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- Prior art keywords
- solid phase
- phase extraction
- outlet sleeve
- leading screw
- mounting base
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
- B01D15/163—Pressure or speed conditioning
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- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a kind of Solid Phase Extraction pressue devices, including：Slide unit, piston there are one being respectively provided in each outlet sleeve on bearing on slide unit, a pressurizing chamber is each respectively formed between piston and the blind end of corresponding outlet sleeve, the outer end of piston rod on each piston is fixedly mounted in mounting base, the blind end of each outlet sleeve is respectively connected with a tracheae, one end of every tracheae is connected with corresponding pressurizing chamber, the other end is used to be connected with solid phase extraction column, sliding driving mechanism in mounting base can drive each outlet sleeve on bearing to move back and forth outside corresponding piston and piston rod, so as to drive the volume of pressurizing chamber in each outlet sleeve to be gradually reduced or gradually increase, when the volume of each pressurizing chamber is gradually reduced, gas in each pressurizing chamber can be extruded into solid phase extraction column.The advantage of the invention is that：It is easy to use, speed of experiment can be accelerated, and can improve experiment precision.
Description
Technical field
The present invention relates to solid phase extraction techniques fields in laboratory.
Background technology
Solid Phase Extraction is a Sample Pretreatment Technique, in the experiment of the multiple fields such as food inspection, environmental analysis, pharmacy
In be widely used.It needs to use solid phase extraction column, solid phase extraction column that there is upper port and lower end in solid phase extraction manipulations
Mouthful, it is provided with filler in solid phase extraction column.In solid phase extraction manipulations, it is small that sample solution is transferred to activated Solid Phase Extraction
In column, sample solution after filler from the lower port of solid phase extraction column by flowing out.
In sample pretreatment process, laboratory worker is frequently encountered following technical problem：One, sample solution exists
Mistake liquid speed degree in solid phase extraction column is slow；Two, mistake liquid speed of the sample solution in solid phase extraction column can not be accurately controlled
Degree；Three, when the multiple solid phase extraction columns of same sample solution point carry out Solid Phase Extraction, all solid phase extraction columns are unable to ensure
It is consistent to cross liquid speed degree.Above-mentioned technical problem not only influences the convenience of experimental implementation, and the essence of experimental result can be influenced toward contact
Parasexuality.
Invention content
The technical problem to be solved in the invention is：Liquid speed degree can be accelerated and can make multiple solid phases by providing one kind
The Solid Phase Extraction pressue device that the mistake liquid speed degree of extraction pillar is consistent.
To solve the above problems, the technical solution adopted by the present invention is：Solid Phase Extraction pressue device, including：Mounting base, peace
Be movably set with slide unit on dress seat, bearing be installed on slide unit, be equipped on bearing it is several horizontal and be mutually parallel plus
Pressing sleeve pipe, one end of each outlet sleeve is open, the other end is all closed, and is respectively provided in each outlet sleeve there are one piston,
It is each to be respectively formed a closed pressurizing chamber between piston and the blind end of corresponding outlet sleeve, each piston with a work
Stopper rod is fixedly connected, and the outer end of every piston rod is stretched out from the open end of corresponding outlet sleeve and is fixedly mounted on mounting base
On, the blind end of each outlet sleeve is respectively connected with a tracheae, one end of every tracheae is connected with corresponding pressurizing chamber,
The other end is used to be connected with a solid phase extraction column equipped with sample solution, and sliding driving machine is additionally provided in mounting base
Structure, sliding driving mechanism can drive slide unit to slidably reciprocate in mounting base, and then drive each outlet sleeve on bearing right
Move back and forth outside the piston and piston rod answered, so as to drive the volume of pressurizing chamber in each outlet sleeve to be gradually reduced or gradually
Increase, when the volume of each pressurizing chamber is gradually reduced, the gas in each pressurizing chamber can be extruded into corresponding with pressurizing chamber
In the solid phase extraction column of connection, to the sample solution pressurization in solid phase extraction column.
Further, Solid Phase Extraction pressue device above-mentioned, wherein the structure of bearing includes：Support body, support body
Both ends be respectively arranged with support plate, several open-topped card slots are respectively provided in the support plate often held, in the support plate at both ends
Card slot correspond, the both ends of every outlet sleeve are respectively fastened in corresponding a pair of of card slot；Every outlet sleeve
The both ends of outer wall are respectively arranged with retainer, the retainer at every outlet sleeve both ends respectively support plate of the block at both ends
Outside.
Further, Solid Phase Extraction pressue device above-mentioned, wherein the structure for sliding driving mechanism includes：In mounting base
It is provided with leading screw, nut is provided on leading screw, the both ends of leading screw are distinguished in bearing block of the expansion bearing in mounting base, leading screw
One end is connected with the output shaft of motor, and slide unit is connected with nut, motor can drive leading screw in bearing block forward or backwards
Rotation, so as to drive the nut on leading screw that slide unit is driven to move back and forth in mounting base.
Further, Solid Phase Extraction pressue device above-mentioned, wherein be respectively arranged with one in the mounting base of leading screw both sides
Root directive slide track, every directive slide track are arranged each parallel to leading screw, the bottom of slide unit be provided with respectively with two directive slide track phases
The guide chute of cooperation, leading screw rotation can drive nut drive the guide chute of slide unit bottom on corresponding directive slide track back and forth
Sliding.
Still further, Solid Phase Extraction pressue device above-mentioned, wherein the leading screw is ball-screw.
Still further, Solid Phase Extraction pressue device above-mentioned, wherein the motor is servo deceleration motor, leading screw
One end stretch out after corresponding bearing block and be connected with the output shaft of servo deceleration motor by shaft coupling.
It is an advantage of the invention that：One, it can pressurize to the sample solution in each solid phase extraction column so that each solid phase extraction
Take the sample solution in pillar that can be flowed out quickly through the filler in solid phase extraction column, to greatly accelerate test into
Degree.Two, it can pressurize to a solid phase extraction column, pressurization can also be carried out at the same time to multiple solid phase extraction columns, made
It uses very convenient.Three, pressurization can be carried out at the same time to multiple solid phase extraction columns of same sample solution so that multiple solid phases
The mistake liquid speed degree of sample solution in extraction pillar is consistent, to substantially increase the precision of experiment.Four, structure letter
It is single, of low cost, easy to operate.
Description of the drawings
Fig. 1 is the structural schematic diagram of Solid Phase Extraction pressue device of the present invention.
Fig. 2 is the structural schematic diagram of A-A section view directions in Fig. 1.
Fig. 3 is the structural schematic diagram of holder shown in Fig. 1 overlook directions.
Fig. 4 is the structural schematic diagram in Fig. 3 left views direction.
Specific implementation mode
The present invention is described in further detail with preferred embodiment below in conjunction with the accompanying drawings.
As shown in Figure 1, Figure 2, Figure 3, Figure 4, Solid Phase Extraction pressue device, including：Mounting base 1, activity setting in mounting base 1
There is slide unit 2, bearing 3 is installed on slide unit 2, outlet sleeve 4 that is several horizontal and being mutually parallel is installed on bearing 3.Add
The quantity of pressing sleeve pipe 4 can need specific setting according to experiment.In the present embodiment, the structure of bearing 3 includes：Support body 31,
The both ends of support body 31 are respectively arranged with support plate 32, and several open-topped card slots are respectively provided in the support plate 32 often held
321, the card slot 321 in the support plate 32 at both ends corresponds, and the both ends of every outlet sleeve 4 are respectively fastened on corresponding
In a pair of of card slot 321.Retainer 44, the block at every 4 both ends of outlet sleeve is respectively set in the both ends of every 4 outer wall of outlet sleeve
Portion 44 respectively block outside the support plate 32 at both ends.
One end of each outlet sleeve 4 is open, the other end is all closed.It is living there are one being respectively provided in each outlet sleeve 4
Plug 41, is respectively formed a closed pressurizing chamber 42, each piston between each piston 41 and the blind end of corresponding outlet sleeve 4
41 are fixedly connected with a piston rod 43, and the outer end of every piston rod 43 is stretched out from the open end of corresponding outlet sleeve 4
And it is fixedly mounted in mounting base 1.The blind end of each outlet sleeve 4 is respectively connected with a tracheae 5.One end of every tracheae 5
It is connected with corresponding pressurizing chamber 42, the other end is used to the closed company of solid phase extraction column that sample solution is housed with one
It is logical.Sliding driving mechanism is additionally provided in mounting base 1, sliding driving mechanism can drive slide unit 2 to slidably reciprocate in mounting base 1,
And then each outlet sleeve 4 on bearing 3 is driven to move back and forth outside corresponding piston 41 and piston rod 43, it is every so as to drive
The volume of pressurizing chamber 42 is gradually reduced or gradually increases in a outlet sleeve 4, when the volume of each pressurizing chamber 42 is gradually reduced,
Gas in each pressurizing chamber 42 can be extruded into the solid phase extraction column of connection corresponding with pressurizing chamber 42, to extract to solid phase
The sample solution in pillar is taken to pressurize.
Specifically, the structure of the sliding driving mechanism described in the present embodiment includes：Leading screw 6, institute are provided in mounting base 1
The leading screw 6 stated is ball-screw, and nut 7 is provided on leading screw 6, and axis of the expansion bearing in mounting base 1 is distinguished at the both ends of leading screw 6
In bearing 11, one end of leading screw 6 is connected with the output shaft of motor 8, and slide unit 2 is connected with nut 7, and motor 8 can drive leading screw 6
It rotates in bearing block 11, is moved back so as to drive the nut 7 on leading screw 6 to drive slide unit 2 in mounting base 1 forward or backwards
It is dynamic.For the ease of automatically controlling, the motor 8 uses servo deceleration motor, one end of leading screw 6 to stretch out corresponding bearing block 11
It is connected afterwards with the output shaft of servo deceleration motor by shaft coupling 13.In order to improve the stabilization that slide unit 2 is run in mounting base 1
Property, a directive slide track 12 is respectively arranged in the present embodiment in the mounting base 1 of 6 both sides of leading screw, every directive slide track 12 is flat
Row is arranged in leading screw 6, the bottom of slide unit 2 be provided with respectively with two 12 matched guide chutes 21 of directive slide track, 6 turns of leading screw
Kinetic energy driving nut 7 drives the guide chute 21 of 2 bottom of slide unit to slidably reciprocate on corresponding directive slide track 12.
Operation principle is as follows：Motor 8 first drives slide unit 2 that the outlet sleeve 4 on bearing 3 is driven to move so that each pressurization
The volume of pressurizing chamber 42 in casing 4 gradually increases, and air is respectively enterd from every tracheae 5 to corresponding pressurizing chamber 42；
Then by the upper port of the solid phase extraction column equipped with sample solution by solid phase extraction column adapter respectively with a tracheae 5
It is tightly connected；Then motor drives slide unit 2 to drive 4 counter motion of outlet sleeve on bearing 3 again so that each pressurizing chamber 42
Volume is gradually reduced, and to be squeezed the air in pressurizing chamber 42 respectively into the corresponding solid phase extraction column being connected, that is, is given
Sample solution pressurization in each solid phase extraction column, sample solution in solid phase extraction column each in this way can be quickly through
Filler in solid phase extraction column and flow out, to greatly accelerate experiment progress.
In the above-mentioned course of work, the movement velocity of outlet sleeve 4 can be adjusted by adjusting the rotating speed of motor 8, from
And adjust the mistake liquid speed degree of sample solution in solid phase extraction column, the mistake liquid speed degree of sample solution in such solid phase extraction column
It can be precisely controlled.Different sample solutions can select adaptable mistake liquid speed degree, which greatly enhances experiment can
By property and precision.Above-mentioned Solid Phase Extraction pressue device can pressurize to a solid phase extraction column, can also be to more
A solid phase extraction column is carried out at the same time pressurization, very convenient to use.To multiple solid phase extraction columns of same sample solution
It is carried out at the same time pressurization, can be so that the mistake liquid speed degree of the sample solution in multiple solid phase extraction columns be consistent, this is also carried significantly
The high precision of experiment.
Claims (6)
1. Solid Phase Extraction pressue device, including：Mounting base is movably set with slide unit in mounting base, it is characterised in that：It is solid on slide unit
Dingan County is equipped with bearing, outlet sleeve that is several horizontal and being mutually parallel is equipped on bearing, one end of each outlet sleeve is opened
Mouthful, the other end be all closed, be respectively provided in each outlet sleeve there are one piston, the closing of each piston and corresponding outlet sleeve
A closed pressurizing chamber is respectively formed between end, each piston is fixedly connected with a piston rod, the outer end of every piston rod
It stretches out and is fixedly mounted in mounting base from the open end of corresponding outlet sleeve, the blind end of each outlet sleeve is all connected with
Have a tracheae, one end of every tracheae is connected with corresponding pressurizing chamber, the other end be used to one it is molten equipped with sample
The solid phase extraction column of liquid is connected, and sliding driving mechanism is additionally provided in mounting base, and sliding driving mechanism can drive slide unit to exist
It slidably reciprocates in mounting base, and then each outlet sleeve on bearing is driven to move back and forth outside corresponding piston and piston rod,
So as to drive the volume of pressurizing chamber in each outlet sleeve to be gradually reduced or gradually increase, when the volume of each pressurizing chamber is gradual
When reduction, the gas in each pressurizing chamber can be extruded into the solid phase extraction column of connection corresponding with pressurizing chamber, to give
Sample solution pressurization in solid phase extraction column.
2. Solid Phase Extraction pressue device according to claim 1, it is characterised in that：The structure of bearing includes：Support body,
The both ends of support body are respectively arranged with support plate, and several open-topped card slots are respectively provided in the support plate often held, both ends
Card slot in support plate corresponds, and the both ends of every outlet sleeve are respectively fastened in corresponding a pair of of card slot；Every
The both ends of outlet sleeve outer wall are respectively arranged with retainer, the retainer at every outlet sleeve both ends respectively block at both ends
Outside support plate.
3. Solid Phase Extraction pressue device according to claim 1 or 2, it is characterised in that：Slide the structure packet of driving mechanism
It includes：It is provided with leading screw in mounting base, nut is provided on leading screw, bearing of the expansion bearing in mounting base is distinguished at the both ends of leading screw
In seat, one end of leading screw is connected with the output shaft of motor, and slide unit is connected with nut, and motor can drive leading screw in bearing block
It rotates forward or backwards, so as to drive the nut on leading screw that slide unit is driven to move back and forth in mounting base.
4. Solid Phase Extraction pressue device according to claim 3, it is characterised in that：It is set respectively in the mounting base of leading screw both sides
It is equipped with a directive slide track, every directive slide track is arranged each parallel to leading screw, and the bottom of slide unit is provided with to be oriented to two respectively
The matched guide chute of sliding rail, leading screw rotation can drive nut to drive the guide chute of slide unit bottom in corresponding directive slide track
On slidably reciprocate.
5. Solid Phase Extraction pressue device according to claim 3, it is characterised in that：The leading screw is ball-screw.
6. Solid Phase Extraction pressue device according to claim 3, it is characterised in that：The motor is servo deceleration electricity
Machine, one end of leading screw, which is stretched out after corresponding bearing block, to be connected by shaft coupling with the output shaft of servo deceleration motor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610818644.0A CN106178596B (en) | 2016-09-13 | 2016-09-13 | Solid Phase Extraction pressue device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610818644.0A CN106178596B (en) | 2016-09-13 | 2016-09-13 | Solid Phase Extraction pressue device |
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| Publication Number | Publication Date |
|---|---|
| CN106178596A CN106178596A (en) | 2016-12-07 |
| CN106178596B true CN106178596B (en) | 2018-08-17 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610818644.0A Active CN106178596B (en) | 2016-09-13 | 2016-09-13 | Solid Phase Extraction pressue device |
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| CN (1) | CN106178596B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109443875A (en) * | 2018-12-10 | 2019-03-08 | 华南农业大学 | A kind of Solid Phase Extraction pressure aid device and system |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012513373A (en) * | 2008-12-22 | 2012-06-14 | バイエル ファーマ アクチエンゲゼルシャフト | Method for synthesizing radionuclide-labeled compounds |
| CN101601938B (en) * | 2009-07-20 | 2011-06-22 | 中国检验检疫科学研究院 | Independent pressurizing and liquid feeding apparatus for solid phase chromatography |
| CN101947393A (en) * | 2010-08-23 | 2011-01-19 | 东南大学 | Split-type nanometer fibre solid-phase extraction column and application thereof |
| CN203220779U (en) * | 2013-04-13 | 2013-10-02 | 云南省烟草农业科学研究院 | Simple solid-phase extraction complete device facilitating closed connection fit |
| CN104707359A (en) * | 2013-12-11 | 2015-06-17 | 北京思践通科技发展有限公司 | Automatic solid phase extraction apparatus |
| CN203842349U (en) * | 2014-04-15 | 2014-09-24 | 东南大学 | Pressurizing device for nanofiber solid-phase extraction column |
| CN205307870U (en) * | 2016-01-19 | 2016-06-15 | 山东标准检测技术有限公司 | Pressurization solid phase extraction device |
| CN206152401U (en) * | 2016-09-13 | 2017-05-10 | 中华人民共和国张家港出入境检验检疫局 | Solid -phase extraction pressure device |
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| CN106178596A (en) | 2016-12-07 |
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