CN106178596A - Solid-Phase Extraction pressue device - Google Patents
Solid-Phase Extraction pressue device Download PDFInfo
- Publication number
- CN106178596A CN106178596A CN201610818644.0A CN201610818644A CN106178596A CN 106178596 A CN106178596 A CN 106178596A CN 201610818644 A CN201610818644 A CN 201610818644A CN 106178596 A CN106178596 A CN 106178596A
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- CN
- China
- Prior art keywords
- phase extraction
- outlet sleeve
- solid
- mounting seat
- leading screw
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
- B01D15/163—Pressure or speed conditioning
Abstract
nullThe invention discloses a kind of Solid-Phase Extraction pressue device，Including: slide unit，A piston it is provided with in each outlet sleeve on bearing on slide unit，A pressurizing chamber it is respectively formed between each piston with the blind end of corresponding outlet sleeve，The outer end of the piston rod on each piston is all fixedly mounted in mounting seat，The blind end of each outlet sleeve is respectively connected with a trachea，One end of every trachea is all connected with corresponding pressurizing chamber、The other end is used to be connected with solid phase extraction column，Each outlet sleeve that sliding drive mechanism in mounting seat can be ordered about on bearing moves back and forth outside corresponding piston and piston rod，It is gradually reduced it is thus possible to order about the volume of pressurizing chamber in each outlet sleeve or is gradually increased，When the volume of each pressurizing chamber is gradually reduced，Gas in each pressurizing chamber all can be extruded in solid phase extraction column.It is an advantage of the current invention that: easy to use, can accelerate speed of experiment, and experiment precision can be improved.
Description
Technical field
The present invention relates to solid phase extraction techniques field in laboratory.
Background technology
Solid-Phase Extraction is a Sample Pretreatment Technique, in the experiment in multiple fields such as food inspection, environmental analysis, pharmacy
In be widely used.Needing in solid phase extraction manipulations to use solid phase extraction column, solid phase extraction column has upper port and lower end
Mouthful, it is provided with filler in solid phase extraction column.In solid phase extraction manipulations, the Solid-Phase Extraction that sample solution is transferred to activate is little
In post, sample solution is by flowing out from the lower port of solid phase extraction column after filler.
In sample pretreatment process, laboratory worker is frequently encountered techniques below problem: one, sample solution exists
Liquid speed excessively in solid phase extraction column is slow；Two, the sample solution speed of liquid excessively in solid phase extraction column cannot accurately be controlled
Degree；Three, when same sample solution divides multiple solid phase extraction column to carry out Solid-Phase Extraction, it is impossible to guarantee all solid phase extraction columns
Cross liquid speed consistent.Above-mentioned technical problem not only affects the convenience of experimental implementation, can affect the essence of experimental result toward contact
Parasexuality.
Summary of the invention
The technical issues that need to address of the present invention are: provide one can accelerate liquid speed and can make multiple solid phase
Extract pillar crosses the Solid-Phase Extraction pressue device that liquid speed keeps consistent.
For solving the problems referred to above, the technical solution used in the present invention is: Solid-Phase Extraction pressue device, including: mounting seat, peace
It is movably set with slide unit on dress seat, slide unit is installed with bearing, bearing is provided with some levels and adding of being parallel to each other
Gland pipe, the equal opening in one end of each outlet sleeve, the other end are all closed, and are provided with a piston in each outlet sleeve,
Be respectively formed an airtight pressurizing chamber between each piston with the blind end of corresponding outlet sleeve, each piston all with a work
Stopper rod is fixing to be connected, and the outer end of every piston rod is all stretched out from the opening of corresponding outlet sleeve and is fixedly mounted on mounting seat
On, the blind end of each outlet sleeve is respectively connected with a trachea, one end of every trachea is all connected with corresponding pressurizing chamber,
The other end is used to be connected equipped with the solid phase extraction column of sample solution with one, mounting seat is additionally provided with sliding and drives machine
Structure, sliding drive mechanism can drive slide unit to slidably reciprocate in mounting seat, and then orders about each outlet sleeve on bearing right
Move back and forth outside the piston answered and piston rod, be gradually reduced or gradually it is thus possible to order about the volume of pressurizing chamber in each outlet sleeve
Increasing, when the volume of each pressurizing chamber is gradually reduced, the gas in each pressurizing chamber all can be extruded into corresponding with pressurizing chamber
In the solid phase extraction column of connection, thus give the sample solution pressurization in solid phase extraction column.
Further, aforesaid Solid-Phase Extraction pressue device, wherein, the structure of bearing includes: support body, support body
Two ends be respectively arranged with gripper shoe, the gripper shoe often held is respectively provided with some open-topped draw-in grooves, in the gripper shoe at two ends
Draw-in groove one_to_one corresponding, the two ends of every outlet sleeve are fastened in a pair corresponding draw-in groove respectively；Every outlet sleeve
The two ends of outer wall are respectively arranged with retainer, the retainer at the every outlet sleeve two ends block respectively gripper shoe at two ends
Outward.
Further, aforesaid Solid-Phase Extraction pressue device, wherein, the structure of sliding drive mechanism includes: in mounting seat
It is provided with leading screw, leading screw is provided with nut, in the expansion bearing bearing block in mounting seat respectively of the two ends of leading screw, leading screw
One end is connected with the output shaft of motor, and slide unit is connected with nut, motor can drive leading screw in bearing block forward or backwards
Rotate, it is thus possible to drive the nut on leading screw to drive slide unit to move back and forth in mounting seat.
Further, aforesaid Solid-Phase Extraction pressue device, wherein, the mounting seat of leading screw both sides is respectively arranged with one
Root directive slide track, every directive slide track is arranged each parallel to leading screw, the bottom of slide unit be provided with respectively with two directive slide track phases
The guide chute coordinated, screw turns can drive nut drive the guide chute bottom slide unit on corresponding directive slide track back and forth
Slide.
Yet further, aforesaid Solid-Phase Extraction pressue device, wherein, described leading screw is ball-screw.
Yet further, aforesaid Solid-Phase Extraction pressue device, wherein, described motor is servo deceleration motor, leading screw
One end stretch out correspondence bearing block after be connected by the output shaft of shaft coupling with servo deceleration motor.
The invention have the advantage that one, the sample solution in each solid phase extraction column can be pressurizeed so that each solid phase extracts
Take the sample solution in pillar to flow out quickly through the filler in solid phase extraction column, thus be greatly accelerated test into
Degree.Two, a solid phase extraction column can be pressurizeed, it is also possible to multiple solid phase extraction columns are pressurizeed simultaneously, makes
Use very convenient.Three, multiple solid phase extraction columns of same sample solution can be pressurizeed simultaneously so that multiple solid phases
The liquid speed of crossing of the sample solution in extraction pillar keeps consistent, thus substantially increases the precision of experiment.Four, structure letter
Single, with low cost, easy to operate.
Accompanying drawing explanation
Fig. 1 is the structural representation of Solid-Phase Extraction pressue device of the present invention.
Fig. 2 is the structural representation in A-A section view direction in Fig. 1.
Fig. 3 is the structural representation that Fig. 1 overlooks the support shown in direction.
Fig. 4 is the structural representation in Fig. 3 left view direction.
Detailed description of the invention
The present invention is described in further detail with preferred embodiment below in conjunction with the accompanying drawings.
As shown in Figure 1, Figure 2, Figure 3, Figure 4, Solid-Phase Extraction pressue device, including: mounting seat 1, movable setting in mounting seat 1
There is slide unit 2, slide unit 2 is installed with bearing 3, bearing 3 is provided with some levels and the outlet sleeve 4 being parallel to each other.Add
The quantity of gland pipe 4 can need concrete setting according to experiment.In the present embodiment, the structure of bearing 3 includes: support body 31,
The two ends of support body 31 are respectively arranged with gripper shoe 32, and the gripper shoe 32 often held is respectively provided with some open-topped draw-in grooves
321, draw-in groove 321 one_to_one corresponding in the gripper shoe 32 at two ends, the two ends of every outlet sleeve 4 are fastened on corresponding respectively
In a pair draw-in groove 321.The two ends of every outlet sleeve 4 outer wall are respectively provided with retainer 44, the block at every outlet sleeve 4 two ends
Portion 44 block respectively is outside the gripper shoe 32 at two ends.
The equal opening in one end of each outlet sleeve 4, the other end are all closed.A work it is provided with in each outlet sleeve 4
Plug 41, is respectively formed an airtight pressurizing chamber 42, each piston between each piston 41 with the blind end of corresponding outlet sleeve 4
41 all fixing with a piston rod 43 are connected, and the outer end of every piston rod 43 is all stretched out from the opening of the outlet sleeve 4 of correspondence
And be fixedly mounted in mounting seat 1.The blind end of each outlet sleeve 4 is respectively connected with a trachea 5.One end of every trachea 5
All be connected with corresponding pressurizing chamber 42, the other end is used to and an airtight company of the solid phase extraction column equipped with sample solution
Logical.Being additionally provided with sliding drive mechanism in mounting seat 1, sliding drive mechanism can drive slide unit 2 to slidably reciprocate in mounting seat 1,
And then each outlet sleeve 4 ordered about on bearing 3 moves back and forth outside corresponding piston 41 and piston rod 43, it is thus possible to order about every
In individual outlet sleeve 4, the volume of pressurizing chamber 42 is gradually reduced or is gradually increased, when the volume of each pressurizing chamber 42 is gradually reduced,
Gas in each pressurizing chamber 42 can be extruded in the solid phase extraction column of connection corresponding with pressurizing chamber 42, thus extracts to solid phase
Take the sample solution pressurization in pillar.
Specifically, the structure of the sliding drive mechanism described in the present embodiment includes: be provided with leading screw 6, institute in mounting seat 1
The leading screw 6 stated is ball-screw, and leading screw 6 is provided with nut 7, the two ends of leading screw 6 expansion bearing axle in mounting seat 1 respectively
In bearing 11, one end of leading screw 6 is connected with the output shaft of motor 8, and slide unit 2 is connected with nut 7, and motor 8 can drive leading screw 6
Bearing block 11 rotates forward or backwards, it is thus possible to drive the nut 7 on leading screw 6 to drive slide unit 2 to move back in mounting seat 1
Dynamic.For the ease of automatically controlling, described motor 8 uses servo deceleration motor, one end of leading screw 6 to stretch out the bearing block 11 of correspondence
It is connected by the output shaft of shaft coupling 13 with servo deceleration motor afterwards.For stablizing of improving that slide unit 2 runs in mounting seat 1
Property, the present embodiment is respectively arranged with in the mounting seat 1 of leading screw 6 both sides a directive slide track 12, every directive slide track 12 is the most flat
Row is arranged in leading screw 6, and the bottom of slide unit 2 is provided with the guide chute 21 matched respectively, leading screw 6 turns with two directive slide tracks 12
Kinetic energy drives nut 7 to drive the guide chute 21 bottom slide unit 2 to slidably reciprocate on corresponding directive slide track 12.
Operation principle is as follows: motor 8 first orders about slide unit 2 and drives the outlet sleeve 4 on bearing 3 to move so that each pressurization
The volume of the pressurizing chamber 42 in sleeve pipe 4 is gradually increased, and air respectively enters from every trachea 5 to corresponding pressurizing chamber 42；
Then will be equipped with sample solution solid phase extraction column upper port by solid phase extraction column adaptor respectively with a trachea 5
It is tightly connected；Then motor orders about slide unit 2 again and drives outlet sleeve 4 adverse movement on bearing 3 so that each pressurizing chamber 42
Volume is gradually reduced, thus is extruded respectively by the air in pressurizing chamber 42 to correspondence in the solid phase extraction column being connected, and i.e. gives
Sample solution pressurization in each solid phase extraction column, the sample solution in the most each solid phase extraction column just can be quickly through
Filler in solid phase extraction column and flow out, thus be greatly accelerated experiment progress.
In above-mentioned work process, the movement velocity of outlet sleeve 4 can be adjusted by adjusting the rotating speed of motor 8, from
And adjusting the liquid speed excessively of sample solution in solid phase extraction column, in such solid phase extraction column, sample solution crosses liquid speed
Can be precisely controlled.What different sample solutions can select to adapt crosses liquid speed, and which greatly enhances experiment can
By property and precision.One solid phase extraction column can be pressurizeed by above-mentioned Solid-Phase Extraction pressue device, it is also possible to many
Individual solid phase extraction column pressurizes simultaneously, very convenient to use.Multiple solid phase extraction columns to same sample solution
Pressurizeing simultaneously, the liquid speed of crossing of the sample solution in multiple solid phase extraction column can be made to keep consistent, this carries the most significantly
The high precision of experiment.
Claims (6)
1. Solid-Phase Extraction pressue device, including: mounting seat, mounting seat is movably set with slide unit, it is characterised in that: solid on slide unit
Dingan County, equipped with bearing, bearing is provided with some levels and the outlet sleeve being parallel to each other, and one end of each outlet sleeve is all opened
Mouthful, the other end all close, be provided with a piston in each outlet sleeve, the closing of each piston and corresponding outlet sleeve
Being respectively formed an airtight pressurizing chamber between end, each piston is all fixing with a piston rod to be connected, the outer end of every piston rod
All openings from corresponding outlet sleeve stretch out and are fixedly mounted on mounting seat, and the blind end of each outlet sleeve is all connected with
Having a trachea, one end of every trachea is all connected with corresponding pressurizing chamber, the other end is used to molten equipped with sample with one
The solid phase extraction column of liquid is connected, and mounting seat is additionally provided with sliding drive mechanism, and sliding drive mechanism can drive slide unit to exist
Slidably reciprocate in mounting seat, and then each outlet sleeve ordered about on bearing move back and forth outside corresponding piston and piston rod,
Be gradually reduced it is thus possible to order about the volume of pressurizing chamber in each outlet sleeve or be gradually increased, when each pressurizing chamber volume gradually
During reduction, the gas in each pressurizing chamber all can be extruded in the solid phase extraction column of connection corresponding with pressurizing chamber, thus gives
Sample solution pressurization in solid phase extraction column.
Solid-Phase Extraction pressue device the most according to claim 1, it is characterised in that: the structure of bearing includes: support body,
The two ends of support body are respectively arranged with gripper shoe, and the gripper shoe often held is respectively provided with some open-topped draw-in grooves, two ends
Draw-in groove one_to_one corresponding in gripper shoe, the two ends of every outlet sleeve are fastened in a pair corresponding draw-in groove respectively；Every
The two ends of outlet sleeve outer wall are respectively arranged with retainer, and the retainer at every outlet sleeve two ends block respectively is at two ends
Outside gripper shoe.
Solid-Phase Extraction pressue device the most according to claim 1 and 2, it is characterised in that: the structure bag of sliding drive mechanism
Include: in mounting seat, be provided with leading screw, leading screw is provided with nut, the two ends of leading screw expansion bearing bearing in mounting seat respectively
In Zuo, one end of leading screw is connected with the output shaft of motor, and slide unit is connected with nut, and motor can drive leading screw in bearing block
Rotate forward or backwards, it is thus possible to drive the nut on leading screw to drive slide unit to move back and forth in mounting seat.
Solid-Phase Extraction pressue device the most according to claim 3, it is characterised in that: set respectively in the mounting seat of leading screw both sides
Being equipped with a directive slide track, every directive slide track is arranged each parallel to leading screw, the bottom of slide unit be provided with respectively with two guiding
The guide chute that slide rail matches, screw turns can drive nut to drive the guide chute bottom slide unit at corresponding directive slide track
On slidably reciprocate.
Solid-Phase Extraction pressue device the most according to claim 3, it is characterised in that: described leading screw is ball-screw.
Solid-Phase Extraction pressue device the most according to claim 3, it is characterised in that: described motor is servo deceleration electricity
Machine, one end of leading screw is connected by the output shaft of shaft coupling with servo deceleration motor after stretching out corresponding bearing block.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610818644.0A CN106178596B (en) | 2016-09-13 | 2016-09-13 | Solid Phase Extraction pressue device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610818644.0A CN106178596B (en) | 2016-09-13 | 2016-09-13 | Solid Phase Extraction pressue device |
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| Publication Number | Publication Date |
|---|---|
| CN106178596A true CN106178596A (en) | 2016-12-07 |
| CN106178596B CN106178596B (en) | 2018-08-17 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610818644.0A Active CN106178596B (en) | 2016-09-13 | 2016-09-13 | Solid Phase Extraction pressue device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109443875A (en) * | 2018-12-10 | 2019-03-08 | 华南农业大学 | A kind of Solid Phase Extraction pressure aid device and system |
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| WO2010072342A2 (en) * | 2008-12-22 | 2010-07-01 | Bayer Schering Pharma Aktiengesellschaft | A method for the synthesis of a radionuclide-labeled compound |
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| CN109443875A (en) * | 2018-12-10 | 2019-03-08 | 华南农业大学 | A kind of Solid Phase Extraction pressure aid device and system |
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| CN106178596B (en) | 2018-08-17 |
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