CN106178096A - A kind of wound fluid film and preparation method thereof - Google Patents
A kind of wound fluid film and preparation method thereof Download PDFInfo
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- CN106178096A CN106178096A CN201610788184.1A CN201610788184A CN106178096A CN 106178096 A CN106178096 A CN 106178096A CN 201610788184 A CN201610788184 A CN 201610788184A CN 106178096 A CN106178096 A CN 106178096A
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- Prior art keywords
- fluid film
- wound fluid
- wound
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- antibacterial
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/202—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with halogen atoms, e.g. triclosan, povidone-iodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/21—Acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Abstract
The present invention relates to a kind of wound fluid film and preparation method thereof, the composition of described wound fluid film is as follows: polyvinyl acetal 8 12 parts；Chitosan 49 parts；Triethyl citrate 5 15 parts；Antibacterial 15 parts, glycerol 8 20 parts, correctives 15 parts.The present invention has superpower water-proof function, can completely cut off the outside moisture contact to wound after smearing film forming；There is antibacterial, the function of sterilization, the intrusion of extraneous antibacterial after film forming, can be completely cut off, be beneficial to accelerate the healing of wound.
Description
Technical field
The invention belongs to medical supplies field, specifically, relate to a kind of wound fluid film and preparation method thereof.
Background technology
In routine work is lived, people the most often can run into the little wounds of body surface such as skin surface scratch, laceration, scuffing
Mouthful situation, this kind of wound tends to occur in body surface, though will not threat to life, but the pain that this kind of wound brings often carries
Carrying out the inconvenience of Working Life, if processing not in time, can easily cause the most expected consequence due to secondary infection.
The disinfectant such as process maneuver common for this kind of wound is to stop blooding initially with absorbent cotton, ethanol clean wound,
Then wrapped up by gauze or adhesive bandage.There is various bandage on the market, although have cheap, convenient to use etc. excellent
Point, but in use exist following not enough: (1) poor air permeability: conventional adhesive plaster poor air permeability used by bandage, body local is just
The steam of often secretion and perspiration can not penetrate this layer of adhesive plaster, then local skin produced action of soaking；(2) with wound docile
Difference: mostly bandage is to be fixed on wound upper surface by tack coat, and sealing is poor, bandage is easy with the gap of contact skin
Dust or water is had to penetrate into, so that wound infection；(3) bandage size is single: conventional bandage is respectively provided with fixing size,
Being used for slight minor cut or wound, specific to some or that surface is bigger wound site is inconvenient to use.Additionally, due to wound site
There is the existence of the wrapper materials such as bandage, have impact on the normal the most movable, for often needing the activity of accurate operation of human body
It is suppressed, nor attractive in appearance.
Summary of the invention
For overcoming the problem in background technology, the invention provides a kind of wound fluid film and preparation method thereof, described
Wound fluid film belongs to liniment, use just can be formed within the time that wound site is extremely short after smearing transparent, waterproof
Thin film, compared with traditional adhesive bandage, its have attractive in appearance, stealthy, use the advantages such as flexible, waterproof, antibacterial.
Technical scheme disclosed by the invention is as follows: a kind of wound fluid film, the composition of described wound fluid film is such as
Under: polyvinyl acetal 8-12 part；Chitosan 4-9 part；Triethyl citrate 5-15 part；Antibacterial 1-5 part, glycerol 8-20 part,
Correctives 1-5 part.
Preferably, described correctives is one or more in Borneolum Syntheticum, Mentholum, eucalyptus oil, Oleum Caryophylli, tea tree oil.
Preferably, described polyvinyl acetal is polyvinyl butyral.
Preferably, described antibacterial is in methyl hydroxybenzoate, ethyl hydroxybenzoate, chlorobutanol, benzoic acid, benzyl alcohol
One or more.
The invention also discloses the preparation method of a kind of wound fluid film, described preparation method is as follows:
Polyvinyl acetal, chitosan are heated while stirring with triethyl citrate in 30-60 DEG C of water-bath, treats all to dissolve
After Wan Quan, it is added thereto to antibacterial, glycerol and correctives；Mixing and stirring prepares film liquid.
Beneficial effects of the present invention: wound fluid film of the present invention can be formed uniform, transparent, attractive in appearance, super in wound site
The thin film of strong water-proof function, protects wound, isolation wound to contact with extraneous；It is raw that antibacterial therein has suppression bacterial wound
Long, prevent the function of wound infection；；Correctives can improve smear after the abnormal smells from the patient left over, improve the compliance of user.And
When this product uses, owing to the pressure at wound location film exists, wound healing process should not form cicatrix protruding, therefore,
There is the function that suppression cicatrix generates；And whole film is partially formed airtight environment at wound, and extraneous dust or water are not
Easily penetrate into, be beneficial to accelerate the healing of wound, therefore, still there is the function of accelerating wound healing；And this wound fluid film makes
Used time arbitrary area is applied on wound, without fixed dimension, and convenient use, especially facilitate some adhesive bandages to be inconvenient to paste
The wound at place uses.
Detailed description of the invention
Below presently preferred embodiments of the present invention is described in detail so that advantages and features of the invention can be easier to by
It will be appreciated by those skilled in the art that thus protection scope of the present invention is made apparent clear and definite defining.
Embodiment 1: a kind of wound fluid film, the composition of described wound fluid film is as follows: polyvinyl acetal 8-12
Part；Chitosan 4-9 part；Triethyl citrate 5-15 part；Antibacterial 1-5 part, glycerol 8-20 part, correctives 1-5 part.
Embodiment 2: a kind of wound fluid film, the composition of described wound fluid film is as follows: polyvinyl butyral 8-
12 parts；Chitosan 4-9 part；Triethyl citrate 5-15 part；Chlorobutanol 1-5 part, glycerol 8-20 part, Oleum Caryophylli 1-5 part.
Embodiment 3: the preparation method of a kind of wound fluid film, specific as follows: by polyvinyl acetal, chitosan and Fructus Citri Limoniae
Triethylenetetraminehexaacetic acid ester heats while stirring in 30-60 DEG C of water-bath, until all dissolving after completely, be added thereto to antibacterial, glycerol and
Correctives；Mixing and stirring prepares film liquid.
Embodiment 4: a kind of wound fluid film, the composition of described wound fluid film is as follows: polyvinyl butyral 8
Part；Chitosan 4 parts；Triethyl citrate 5 parts；Antibacterial 1 part, glycerol 8 parts, correctives 1 part.
The preparation method of this wound fluid film is as follows: by polyvinyl butyral, chitosan with triethyl citrate in 30-
60 DEG C of water-baths heat while stirring, after all dissolving completely, is added thereto to antibacterial, glycerol and correctives；Mixing is stirred
Mix and uniformly prepare film liquid.
Embodiment 5: a kind of wound fluid film, the composition of described wound fluid film is as follows: polyvinyl butyral 12
Part；Chitosan 9 parts；Triethyl citrate 10 parts；Ethyl hydroxybenzoate 3 parts, glycerol 10 parts, Mentholum 2 parts.
The preparation method of this wound fluid film is as follows: by polyvinyl butyral, chitosan with triethyl citrate in 30-
50 DEG C of water-baths heat while stirring, after all dissolving completely, is added thereto to ethyl hydroxybenzoate, glycerol and Mentholum；Mixed
Conjunction stirs prepared film liquid.
Embodiment 6: a kind of wound fluid film, the composition of described wound fluid film is as follows: polyvinyl butyral 10
Part；Chitosan 5 parts；Triethyl citrate 5 parts；Antibacterial 2 parts, glycerol 10 parts, correctives 5 parts.
The preparation method of this wound fluid film is as follows: by polyvinyl butyral, chitosan with triethyl citrate in 60
DEG C water-bath heats while stirring, after all dissolving completely, is added thereto to antibacterial, glycerol and correctives；Mix and blend
Uniformly prepare film liquid.
Correctives described in the present embodiment is the one in Borneolum Syntheticum, Mentholum, eucalyptus oil, Oleum Caryophylli, tea tree oil.This enforcement
Antibacterial described in example is the one in methyl hydroxybenzoate, ethyl hydroxybenzoate, chlorobutanol, benzoic acid, benzyl alcohol.
Embodiment 7: a kind of wound fluid film, the composition of described wound fluid film is as follows: polyvinyl butyral 11
Part；Chitosan 8 parts；Triethyl citrate 12 parts；Chlorobutanol 3 parts, glycerol 10 parts, tea tree oil 3 parts.
The preparation method of this wound fluid film is as follows: by polyvinyl butyral, chitosan with triethyl citrate in 45
DEG C water-bath heats while stirring, after all dissolving completely, is added thereto to chlorobutanol, glycerol and tea tree oil；Mixing
Stir prepared film liquid.
The foregoing is only embodiments of the invention, not thereby limit the scope of the claims of the present invention, every utilize this
Equivalent structure or equivalence flow process that bright description is made convert, or are directly or indirectly used in other relevant technology necks
Territory, is the most in like manner included in the scope of patent protection of the present invention.
Claims (5)
1. a wound fluid film, it is characterised in that: the composition of described wound fluid film is as follows:
Polyvinyl acetal 8-12 part；Chitosan 4-9 part；Triethyl citrate 5-15 part；Antibacterial 1-5 part, glycerol 8-20 part,
Correctives 1-5 part.
Wound fluid film the most according to claim 1, it is characterised in that: described correctives is Borneolum Syntheticum, Mentholum, eucalyptus globulus
One or more in leaf oil, Oleum Caryophylli, tea tree oil.
Wound fluid film the most according to claim 1, it is characterised in that: described polyvinyl acetal is polyethylene contracting fourth
Aldehyde.
Wound fluid film the most according to claim 1, it is characterised in that: described antibacterial is methyl hydroxybenzoate, Buddhist nun
One or more in pool gold ethyl ester, chlorobutanol, benzoic acid, benzyl alcohol.
5. the preparation method of a wound fluid film, it is characterised in that: described preparation method is as follows:
Polyvinyl acetal, chitosan are heated while stirring with triethyl citrate in 30-60 DEG C of water-bath, treats all to dissolve completely
After, it is added thereto to antibacterial, glycerol and correctives；Mixing and stirring prepares film liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610788184.1A CN106178096A (en) | 2016-08-30 | 2016-08-30 | A kind of wound fluid film and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610788184.1A CN106178096A (en) | 2016-08-30 | 2016-08-30 | A kind of wound fluid film and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106178096A true CN106178096A (en) | 2016-12-07 |
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ID=58086356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610788184.1A Pending CN106178096A (en) | 2016-08-30 | 2016-08-30 | A kind of wound fluid film and preparation method thereof |
Country Status (1)
| Country | Link |
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| CN (1) | CN106178096A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102274542A (en) * | 2011-08-30 | 2011-12-14 | 夏敬民 | Film-forming type waterproof breathable wound protecting liquid and preparation method thereof |
| CN104257639A (en) * | 2014-10-15 | 2015-01-07 | 广东璞石医药科技有限公司 | Film coating agent for wound surface treatment and preparation method of film coating agent |
| CN104971377A (en) * | 2015-06-23 | 2015-10-14 | 潘秀娟 | Liquid wound glue and preparation method |
| CN105816908A (en) * | 2016-04-29 | 2016-08-03 | 哈尔滨乾佰纳生物药业有限公司 | Waterproof liquid wound protection film and preparation method thereof |
-
2016
- 2016-08-30 CN CN201610788184.1A patent/CN106178096A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102274542A (en) * | 2011-08-30 | 2011-12-14 | 夏敬民 | Film-forming type waterproof breathable wound protecting liquid and preparation method thereof |
| CN104257639A (en) * | 2014-10-15 | 2015-01-07 | 广东璞石医药科技有限公司 | Film coating agent for wound surface treatment and preparation method of film coating agent |
| CN104971377A (en) * | 2015-06-23 | 2015-10-14 | 潘秀娟 | Liquid wound glue and preparation method |
| CN105816908A (en) * | 2016-04-29 | 2016-08-03 | 哈尔滨乾佰纳生物药业有限公司 | Waterproof liquid wound protection film and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20161207 |